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Cheap flights from Des Moines to Louisville from $189

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Louisville departing on 9/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

American Airlines Logo
4:08 pm - 11:22 pmDSM-SDF
6h 14m1 stop
American Airlines Logo
10:00 am - 3:23 pmSDF-DSM
6h 23m1 stop
$189American Airlines
Find Deal
Tue, Sep 23 - Sat, Sep 27
American Airlines Logo
7:08 am - 4:48 pmDSM-SDF
8h 40m2 stops
American Airlines Logo
2:42 pm - 5:56 pmSDF-DSM
4h 14m1 stop
$194American Airlines
Find Deal
Tue, Sep 23 - Sat, Sep 27
Delta Logo
7:00 am - 12:01 pmDSM-SDF
4h 01m1 stop
Delta Logo
3:05 pm - 8:33 pmSDF-DSM
6h 28m1 stop
$223Delta
Find Deal
Tue, Jul 29 - Tue, Aug 5
Delta Logo
3:30 pm - 10:53 pmDSM-SDF
6h 23m1 stop
Delta Logo
6:36 am - 10:18 amSDF-DSM
4h 42m1 stop
$241Delta
Find Deal
Sat, Sep 13 - Sun, Sep 14
United Airlines Logo
3:38 pm - 10:14 pmDSM-SDF
5h 36m1 stop
United Airlines Logo
8:40 am - 2:41 pmSDF-DSM
7h 01m1 stop
$262United Airlines
Find Deal
Wed, Jul 30 - Wed, Aug 6
Southwest Logo
7:00 am - 5:40 pmDSM-SDF
9h 40m2 stops
Southwest Logo
2:05 pm - 11:50 pmSDF-DSM
10h 45m2 stops
$279Southwest
Find Deal
Fri, Sep 5 - Sun, Sep 7
 Logo
9:39 am - 7:08 pmDSM-SDF
8h 29m1 stop
 Logo
9:22 pm - 4:14 pmSDF-DSM
19h 52m1 stop
Fri, Aug 8 - Sun, Aug 10
 Logo
9:39 am - 7:08 pmDSM-SDF
8h 29m1 stop
 Logo
9:22 pm - 6:05 pmSDF-DSM
21h 43m2 stops
Fri, Aug 8 - Sun, Aug 10
Southwest Logo
8:35 am - 10:25 pmDSM-SDF
12h 50m2 stops
Southwest Logo
2:05 pm - 11:50 pmSDF-DSM
10h 45m2 stops
$360Southwest
Find Deal
Sat, Sep 13 - Sun, Sep 14
United Airlines Logo
6:50 pm - 1:33 pmDSM-SDF
17h 43m2 stops
United Airlines Logo
9:00 am - 12:14 pmSDF-DSM
4h 14m1 stop
$450United Airlines
Find Deal
Fri, Oct 31 - Sun, Nov 2

United Airlines flights from Des Moines to Louisville

Our best United Airlines deals on Des Moines to Louisville flight tickets
United Airlines
Jul 30
DSM3:38 pmDes Moines
5h 36m
1 stop
SDF10:14 pmLouisville Intl
Aug 6
SDF8:40 amLouisville Intl
7h 01m
1 stop
DSM2:41 pmDes Moines
United Airlines
Oct 31
DSM6:50 pmDes Moines
17h 43m
2 stops
SDF1:33 pmLouisville Intl
Nov 2
SDF9:00 amLouisville Intl
4h 14m
1 stop
DSM12:14 pmDes Moines
United Airlines
Sep 10
DSM3:25 pmDes Moines
5h 59m
1 stop
SDF10:24 pmLouisville Intl
Sep 15
SDF5:52 pmLouisville Intl
17h 54m
2 stops
DSM10:46 amDes Moines

American Airlines flights from Des Moines to Louisville

Our best American Airlines deals on Des Moines to Louisville flight tickets
American Airlines
Sep 23
DSM4:08 pmDes Moines
6h 14m
1 stop
SDF11:22 pmLouisville Intl
Sep 27
SDF10:00 amLouisville Intl
6h 23m
1 stop
DSM3:23 pmDes Moines
American Airlines
Sep 23
DSM7:08 amDes Moines
8h 40m
2 stops
SDF4:48 pmLouisville Intl
Sep 27
SDF2:42 pmLouisville Intl
4h 14m
1 stop
DSM5:56 pmDes Moines
American Airlines
Sep 23
DSM7:08 amDes Moines
8h 40m
2 stops
SDF4:48 pmLouisville Intl
Sep 27
SDF1:06 pmLouisville Intl
8h 14m
2 stops
DSM8:20 pmDes Moines

See travel insights to Louisville from

How to get the cheapest flight ticket from Des Moines to Louisville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Louisville?

If you are unable to visit Louisville during the month of February, then departing from Des Moines during the month June is also very affordable. Most momondo users find prices during this month for around $329.

What is the cheapest day to depart on your flight to Louisville?

On average, the least expensive day to fly to Louisville from Des Moines is on a Tuesday. momondo users have found tickets for Tuesday departures for as low as $333. However, this price may fluctuate depending on the airline, the season, and holidays. Flights from Des Moines to Louisville on a Sunday will generally be more expensive and average around $457. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Louisville?

Our data shows that the cheapest Des Moines to Louisville flights are usually those with departure times at noon. Our users have found flights to Louisville at noon for as low as $322. In the morning is when there is more demand to fly to Louisville, so prices are often more expensive at around $396 per ticket.

How have Des Moines to Louisville flight prices changed over time?

As of June 2025, prices for Des Moines to Louisville flights are approximately 73% more expensive when compared to flights at the same time last year.

When to book flights from Des Moines to Louisville

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Louisville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Louisville (DSM to SDF) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Louisville

Best Price Found

$189

Fastest flight time

4h 01m

Direct flights

None

Airports in Louisville

1 airport
The best flight deal from Des Moines to Louisville found on momondo in the last 72 hours is $189
The fastest flight from Des Moines to Louisville takes 4h 01m
There are no direct flights from Des Moines to Louisville. Popular non-direct route for this connection is Des Moines Airport - Louisville Intl Airport.
There is 1 airport near Louisville: Louisville Intl (SDF)

  • How far is Des Moines to Louisville Intl by plane?

    Louisville Intl is 476.1 mi away from Des Moines. By plane, this route typically takes 4h 01m.

  • When did momondo last update prices for flights from Des Moines Airport to Louisville Intl Airport?

    Prices for flights from Des Moines Airport to Louisville Intl Airport are updated daily.

  • How many operators does momondo search for flights from Des Moines Airport to Louisville Intl Airport?

  • How old do you have to be to fly from Des Moines Airport to Louisville Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Louisville Intl Airport.

  • What documentation or ID do you need to fly to Louisville Intl Airport?

    The necessary travel and health documents for your Louisville Intl Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to Louisville?


Best airlines flying from Des Moines to Louisville

Compare and see reviews for airlines that fly from Des Moines to Louisville with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $246Free CancellationRating
8.0
7,963 reviews
Search Delta flights
American AirlinesPriceFrom $264Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
United AirlinesPriceFrom $306Free CancellationRating
7.4
8,801 reviews
Search United Airlines flights

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
French Lick
Elizabethtown
West Baden Springs
Bardstown
Jeffersonville
Shepherdsville
New Albany
Elizabeth
Corydon
Charlestown
Georgetown
Springfield
Brandenburg

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Louisville?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Des Moines to Louisville. momondo saves you time and could save you money on your trip.

Can I find flights from Des Moines to Louisville with flexible booking policies on momondo?

Yes. All flights to Louisville from Des Moines on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Des Moines to Louisville?

momondo provides multiple filters to help you find the best flight to Louisville from Des Moines. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Des Moines to Louisville right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Des Moines to Louisville now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Louisville and let you know when they change.


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