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Cheap flights from Des Moines to Santo Domingo from $670

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Santo Domingo departing on 11/17. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Des Moines to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:00 am - 11:32 pm
DSM
-
SDQ
15h 32m
1 stop
American Airlines Logo
1:12 pm - 11:16 pm
SDQ
-
DSM
12h 04m
1 stop
$670American Airlines
Tue, Nov 17 - Tue, Nov 24
American Airlines Logo
9:04 am - 11:32 pm
DSM
-
SDQ
12h 28m
2 stops
American Airlines Logo
6:00 am - 2:59 pm
SDQ
-
DSM
10h 59m
2 stops
$675American Airlines
Tue, Nov 17 - Tue, Nov 24
American Airlines Logo
6:00 am - 11:32 pm
DSM
-
SDQ
15h 32m
1 stop
American Airlines Logo
1:12 pm - 11:16 pm
SDQ
-
DSM
12h 04m
1 stop
$680American Airlines
Tue, Nov 17 - Tue, Nov 24
American Airlines Logo
9:04 am - 11:32 pm
DSM
-
SDQ
12h 28m
2 stops
American Airlines Logo
6:00 am - 2:59 pm
SDQ
-
DSM
10h 59m
2 stops
$685American Airlines
Tue, Nov 17 - Tue, Nov 24
United Airlines Logo
3:11 pm - 11:55 am
DSM
-
SDQ
19h 44m
2 stops
United Airlines Logo
3:20 pm - 10:31 am
SDQ
-
DSM
20h 11m
2 stops
$715United Airlines
Tue, Sep 29 - Tue, Oct 6
United Airlines Logo
9:37 am - 10:46 pm
DSM
-
SDQ
12h 09m
2 stops
United Airlines Logo
6:00 am - 9:35 pm
SDQ
-
DSM
17h 35m
2 stops
$755United Airlines
Sat, Oct 31 - Tue, Nov 3
American Airlines Logo
5:00 am - 9:25 pm
DSM
-
SDQ
15h 25m
2 stops
American Airlines Logo
1:57 pm - 10:04 pm
SDQ
-
DSM
9h 07m
1 stop
$765American Airlines
Mon, Jul 13 - Fri, Jul 17
Delta Logo
6:37 pm - 1:17 pm
DSM
-
SDQ
17h 40m
1 stop
Delta Logo
6:05 am - 10:29 pm
SDQ
-
DSM
17h 24m
2 stops
$845Delta
Tue, Jul 14 - Fri, Jul 17
American Airlines Logo
1:04 pm - 12:57 pm
DSM
-
SDQ
22h 53m
1 stop
American Airlines Logo
1:57 pm - 10:04 pm
SDQ
-
DSM
9h 07m
1 stop
$913American Airlines
Mon, Jul 13 - Fri, Jul 17
United Airlines Logo
6:15 am - 11:46 pm
DSM
-
SDQ
15h 31m
2 stops
United Airlines Logo
6:00 am - 11:01 pm
SDQ
-
DSM
19h 01m
2 stops
$990United Airlines
Mon, Dec 14 - Wed, Dec 16

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American Airlines flights from Des Moines to Santo Domingo

Our best American Airlines deals on Des Moines to Santo Domingo flight tickets
American Airlines
Nov 17
DSM6:00 amDes Moines
15h 32m
1 stop
SDQ11:32 pmSanto Domingo Las Americas
Nov 24
SDQ1:12 pmSanto Domingo Las Americas
12h 04m
1 stop
DSM11:16 pmDes Moines
$670
American Airlines
Nov 17
DSM6:39 amDes Moines
14h 53m
2 stops
SDQ11:32 pmSanto Domingo Las Americas
Nov 24
SDQ4:59 pmSanto Domingo Las Americas
8h 17m
1 stop
DSM11:16 pmDes Moines
$675
American Airlines
Nov 17
DSM6:00 amDes Moines
15h 32m
1 stop
SDQ11:32 pmSanto Domingo Las Americas
Nov 24
SDQ1:12 pmSanto Domingo Las Americas
12h 04m
1 stop
DSM11:16 pmDes Moines
$680

United Airlines flights from Des Moines to Santo Domingo

Our best United Airlines deals on Des Moines to Santo Domingo flight tickets
United Airlines
Sep 29
DSM3:11 pmDes Moines
19h 44m
2 stops
SDQ11:55 amSanto Domingo Las Americas
Oct 6
SDQ3:20 pmSanto Domingo Las Americas
20h 11m
2 stops
DSM10:31 amDes Moines
$715
United Airlines
Oct 31
DSM9:37 amDes Moines
12h 09m
2 stops
SDQ10:46 pmSanto Domingo Las Americas
Nov 3
SDQ6:00 amSanto Domingo Las Americas
17h 35m
2 stops
DSM9:35 pmDes Moines
$755
United Airlines
Dec 14
DSM6:15 amDes Moines
15h 31m
2 stops
SDQ11:46 pmSanto Domingo Las Americas
Dec 16
SDQ6:00 amSanto Domingo Las Americas
19h 01m
2 stops
DSM11:01 pmDes Moines
$990

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 28, 2026.
Use the filters below to find and compare flights from Des Moines to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesSanto Domingo

DSM - SDQ

DSMSDQ

Des Moines

Tue 11/17

6:00 am-11:32 pm

1 stop15h 32m

Santo Domingo Las Americas

Tue 11/24

1:12 pm-11:16 pm

1 stop12h 04m

$670
Quickest round-trip

Des MoinesSanto Domingo

DSM - SDQ

DSMSDQ

Des Moines

Tue 11/17

9:04 am-11:32 pm

2 stops12h 28m

Santo Domingo Las Americas

Tue 11/24

6:00 am-2:59 pm

2 stops10h 59m

$675

Des MoinesSanto Domingo

DSM - SDQ

DSMSDQ

Des Moines

Tue 11/17

6:00 am-11:32 pm

1 stop15h 32m

Santo Domingo Las Americas

Tue 11/24

1:12 pm-11:16 pm

1 stop12h 04m

$680

Des MoinesSanto Domingo

DSM - SDQ

DSMSDQ

Des Moines

Tue 11/17

9:04 am-11:32 pm

2 stops12h 28m

Santo Domingo Las Americas

Tue 11/24

6:00 am-2:59 pm

2 stops10h 59m

$685

Des MoinesSanto Domingo

DSM - SDQ

DSMSDQ

Des Moines

Tue 9/29

3:11 pm-11:55 am

2 stops19h 44m

Santo Domingo Las Americas

Tue 10/6

3:20 pm-10:31 am

2 stops20h 11m

$715

Des MoinesSanto Domingo

DSM - SDQ

DSMSDQ

Des Moines

Sat 10/31

9:37 am-10:46 pm

2 stops12h 09m

Santo Domingo Las Americas

Tue 11/3

6:00 am-9:35 pm

2 stops17h 35m

$755

Des MoinesSanto Domingo

DSM - SDQ

DSMSDQ

Des Moines

Mon 7/13

5:00 am-9:25 pm

2 stops15h 25m

Santo Domingo Las Americas

Fri 7/17

1:57 pm-10:04 pm

1 stop9h 07m

$765

Des MoinesSanto Domingo

DSM - SDQ

DSMSDQ

Des Moines

Tue 7/14

6:37 pm-1:17 pm

1 stop17h 40m

Santo Domingo Las Americas

Fri 7/17

6:05 am-10:29 pm

2 stops17h 24m

$845

Des MoinesSanto Domingo

DSM - SDQ

DSMSDQ

Des Moines

Mon 7/13

1:04 pm-12:57 pm

1 stop22h 53m

Santo Domingo Las Americas

Fri 7/17

1:57 pm-10:04 pm

1 stop9h 07m

$913

Des MoinesSanto Domingo

DSM - SDQ

DSMSDQ

Des Moines

Mon 12/14

6:15 am-11:46 pm

2 stops15h 31m

Santo Domingo Las Americas

Wed 12/16

6:00 am-11:01 pm

2 stops19h 01m

$990

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Santo Domingo from

How to get the cheapest flight ticket from Des Moines to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Des Moines to Santo Domingo flights?

You could potentially save up to 12% on your flight if you consider stops on a Des Moines to Santo Domingo flight.

When to book flights from Des Moines to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Santo Domingo (DSM to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Santo Domingo

Fastest flight time

6h 55m

Direct flights

None
The fastest flight from Des Moines to Santo Domingo takes 6h 55m
There are no direct flights from Des Moines to Santo Domingo. There are no popular flight routes from Des Moines to Santo Domingo.
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Frequently asked questions about flying from Des Moines to Santo Domingo

  • How far is Des Moines to Santo Domingo Las Americas by plane?

    There are 2118.5 mi between Des Moines and Santo Domingo Las Americas. By plane, this route typically takes 6h 55m.

  • When did momondo last update prices for flights from Des Moines Airport to Santo Domingo Las Americas Airport?

    Prices for flights from Des Moines Airport to Santo Domingo Las Americas Airport are updated daily.

  • How many operators does momondo search for flights from Des Moines Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from Des Moines Airport to Santo Domingo Las Americas Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The necessary travel and health documents for your Santo Domingo Las Americas Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to Santo Domingo?

Best airlines flying from Des Moines to Santo Domingo

Compare and see reviews for airlines that fly from Des Moines to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $514Free CancellationRating
7.8
8,455 reviews
Search Delta flights
American AirlinesPriceFrom $613Free CancellationRating
7.1
11,776 reviews
Search American Airlines flights

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

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Why should I use momondo to find a flight deal from Des Moines to Santo Domingo?

It is quick and easy to find Des Moines to Santo Domingo flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santo Domingo that suits you.

Can I find flights from Des Moines to Santo Domingo with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santo Domingo from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Santo Domingo?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Des Moines to Santo Domingo.

I’m not ready to book a flight from Des Moines to Santo Domingo right now. Can momondo alert me if prices change?

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