Cheap flights from Des Moines to Illinois from $115

The cheapest month to fly to Illinois from Des Moines is in February. Flight prices, which tend to average around $126, are often lower during this time because this is during the off-season. If you aren’t able to travel to Illinois during the month of February, then flying in July is also cheap. Prices for this month can be found on momondo for an average of $129.

The cheapest day to depart from Des Moines to Illinois is on a Thursday when prices can be found for as low as $510. Flights from Des Moines to Illinois on a Tuesday will generally be more expensive and average around $692. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

Our most recent data shows that the best time of day to fly to Illinois is in the morning. Flights from Des Moines to Illinois during this time can be as low as $503. Flights at noon are often more expensive with an average ticket price of $963.

Fly from Des Moines to Chicago Midway for the best Des Moines - Illinois flight prices

You are more likely to see cheaper flights to Illinois from Des Moines when booking weeks ahead of your departure date. In general, you can expect to find flights to Illinois for around $290 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Illinois from Des Moines for as low as $169 on momondo.

There are 4 cabin classes available to choose from on Des Moines to Illinois flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

As of May 2026, 40 flights take off from Des Moines and land in Illinois each day. The most common flight departure time for this route is 8:00AM, with 36% of daily flights taking off at noon.

285 flights are operational weekly from Des Moines to Illinois as of May 2026. The most popular departure day for this route is Mon, with 18% of flights per week taking off on this day.