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Cheap flights from Des Moines to Hilton Head Island from $410

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Hilton Head Island departing on 4/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Des Moines to Hilton Head Island

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
8:04 am - 2:06 pm
DSM
-
HHH
5h 02m
1 stop
United Airlines Logo
3:00 pm - 9:27 pm
HHH
-
DSM
7h 27m
1 stop
$410United Airlines
Wed, Apr 22 - Tue, Apr 28
United Airlines Logo
8:04 am - 2:06 pm
DSM
-
HHH
5h 02m
1 stop
United Airlines Logo
3:00 pm - 9:27 pm
HHH
-
DSM
7h 27m
1 stop
$415United Airlines
Wed, Apr 22 - Tue, Apr 28
American Airlines Logo
5:54 am - 3:14 pm
DSM
-
HHH
8h 20m
1 stop
American Airlines Logo
5:51 pm - 11:28 am
HHH
-
DSM
18h 37m
2 stops
$440American Airlines
Wed, Apr 22 - Tue, Apr 28
American Airlines Logo
7:00 am - 6:09 pm
DSM
-
HHH
10h 09m
2 stops
American Airlines Logo
5:51 pm - 11:28 am
HHH
-
DSM
18h 37m
2 stops
$446American Airlines
Wed, Apr 22 - Tue, Apr 28
American Airlines Logo
6:26 am - 3:14 pm
DSM
-
HHH
7h 48m
1 stop
American Airlines Logo
5:04 pm - 9:06 pm
HHH
-
DSM
5h 02m
1 stop
$447American Airlines
Sun, Apr 26 - Sat, May 2
American Airlines Logo
6:00 am - 2:26 pm
DSM
-
HHH
7h 26m
2 stops
American Airlines Logo
5:04 pm - 9:06 pm
HHH
-
DSM
5h 02m
1 stop
$452American Airlines
Sun, Apr 26 - Sat, May 2
American Airlines Logo
6:00 am - 4:34 pm
DSM
-
HHH
9h 34m
2 stops
American Airlines Logo
5:04 pm - 12:11 am
HHH
-
DSM
8h 07m
2 stops
$458American Airlines
Sun, Apr 26 - Sat, May 2
American Airlines Logo
7:00 am - 2:22 pm
DSM
-
HHH
6h 22m
1 stop
American Airlines Logo
4:11 pm - 10:10 pm
HHH
-
DSM
6h 59m
1 stop
$474American Airlines
Sun, Mar 29 - Wed, Apr 1
American Airlines Logo
7:00 am - 2:22 pm
DSM
-
HHH
6h 22m
1 stop
American Airlines Logo
2:58 pm - 10:10 pm
HHH
-
DSM
8h 12m
2 stops
$479American Airlines
Sun, Mar 29 - Wed, Apr 1
American Airlines Logo
8:01 pm - 10:32 am
DSM
-
HHH
13h 31m
2 stops
American Airlines Logo
5:51 pm - 11:28 am
HHH
-
DSM
18h 37m
2 stops
$590American Airlines
Thu, Apr 23 - Tue, Apr 28

United Airlines flights from Des Moines to Hilton Head Island

Our best United Airlines deals on Des Moines to Hilton Head Island flight tickets
United Airlines
Apr 22
DSM8:04 amDes Moines
5h 02m
1 stop
HHH2:06 pmHilton Head Island
Apr 28
HHH3:00 pmHilton Head Island
7h 27m
1 stop
DSM9:27 pmDes Moines
$410
United Airlines
Apr 22
DSM8:04 amDes Moines
5h 02m
1 stop
HHH2:06 pmHilton Head Island
Apr 28
HHH3:00 pmHilton Head Island
7h 27m
1 stop
DSM9:27 pmDes Moines
$415
United Airlines
Apr 23
DSM8:04 amDes Moines
30h 26m
3 stops
HHH3:30 pmHilton Head Island
Apr 28
HHH4:11 pmHilton Head Island
23h 14m
2 stops
DSM2:25 pmDes Moines
$942

American Airlines flights from Des Moines to Hilton Head Island

Our best American Airlines deals on Des Moines to Hilton Head Island flight tickets
American Airlines
Apr 22
DSM5:54 amDes Moines
8h 20m
1 stop
HHH3:14 pmHilton Head Island
Apr 28
HHH5:51 pmHilton Head Island
18h 37m
2 stops
DSM11:28 amDes Moines
$440
American Airlines
Apr 22
DSM7:00 amDes Moines
10h 09m
2 stops
HHH6:09 pmHilton Head Island
Apr 28
HHH5:51 pmHilton Head Island
18h 37m
2 stops
DSM11:28 amDes Moines
$446
American Airlines
Apr 26
DSM6:26 amDes Moines
7h 48m
1 stop
HHH3:14 pmHilton Head Island
May 2
HHH5:04 pmHilton Head Island
5h 02m
1 stop
DSM9:06 pmDes Moines
$447

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Hilton Head Island that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 28, 2026.
Use the filters below to find and compare flights from Des Moines to Hilton Head Island that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesHilton Head Island

DSM - HHH

DSMHHH

Des Moines

Wed 4/22

8:04 am-2:06 pm

1 stop5h 02m

Hilton Head Island

Tue 4/28

3:00 pm-9:27 pm

1 stop7h 27m

$410

Des MoinesHilton Head Island

DSM - HHH

DSMHHH

Des Moines

Wed 4/22

8:04 am-2:06 pm

1 stop5h 02m

Hilton Head Island

Tue 4/28

3:00 pm-9:27 pm

1 stop7h 27m

$415

Des MoinesHilton Head Island

DSM - HHH

DSMHHH

Des Moines

Wed 4/22

5:54 am-3:14 pm

1 stop8h 20m

Hilton Head Island

Tue 4/28

5:51 pm-11:28 am

2 stops18h 37m

$440

Des MoinesHilton Head Island

DSM - HHH

DSMHHH

Des Moines

Wed 4/22

7:00 am-6:09 pm

2 stops10h 09m

Hilton Head Island

Tue 4/28

5:51 pm-11:28 am

2 stops18h 37m

$446

Des MoinesHilton Head Island

DSM - HHH

DSMHHH

Des Moines

Sun 4/26

6:26 am-3:14 pm

1 stop7h 48m

Hilton Head Island

Sat 5/2

5:04 pm-9:06 pm

1 stop5h 02m

$447

Des MoinesHilton Head Island

DSM - HHH

DSMHHH

Des Moines

Sun 4/26

6:00 am-2:26 pm

2 stops7h 26m

Hilton Head Island

Sat 5/2

5:04 pm-9:06 pm

1 stop5h 02m

$452

Des MoinesHilton Head Island

DSM - HHH

DSMHHH

Des Moines

Sun 4/26

6:00 am-4:34 pm

2 stops9h 34m

Hilton Head Island

Sat 5/2

5:04 pm-12:11 am

2 stops8h 07m

$458

Des MoinesHilton Head Island

DSM - HHH

DSMHHH

Des Moines

Sun 3/29

7:00 am-2:22 pm

1 stop6h 22m

Hilton Head Island

Wed 4/1

4:11 pm-10:10 pm

1 stop6h 59m

$474

Des MoinesHilton Head Island

DSM - HHH

DSMHHH

Des Moines

Sun 3/29

7:00 am-2:22 pm

1 stop6h 22m

Hilton Head Island

Wed 4/1

2:58 pm-10:10 pm

2 stops8h 12m

$479

Des MoinesHilton Head Island

DSM - HHH

DSMHHH

Des Moines

Thu 4/23

8:01 pm-10:32 am

2 stops13h 31m

Hilton Head Island

Tue 4/28

5:51 pm-11:28 am

2 stops18h 37m

$590

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Hilton Head Island from

How to get the cheapest flight ticket from Des Moines to Hilton Head Island

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What airlines fly to Hilton Head Island?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Hilton Head Island from Des Moines according to our data. American Airlines is the first choice among our users, with 62% of people opting to fly with this airline when traveling to Hilton Head Island. Keep in mind that there are 3 different airlines that fly to Hilton Head Island on a routine basis, so you have a few additional options to choose from.

When to book flights from Des Moines to Hilton Head Island

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Hilton Head Island according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Hilton Head Island (DSM to HHH) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Hilton Head Island

Fastest flight time

5h 02m

Direct flights

None
The fastest flight from Des Moines to Hilton Head Island takes 5h 02m
There are no direct flights from Des Moines to Hilton Head Island. There are no popular flight routes from Des Moines to Hilton Head Island.
Search flight deals

  • How far is Des Moines to Hilton Head Island by plane?

    Des Moines and Hilton Head Island are 959.2 mi apart from one another. By plane, this route typically takes 5h 02m.

  • When did momondo last update prices for flights from Des Moines Airport to Hilton Head Island Airport?

    Prices for flights from Des Moines Airport to Hilton Head Island Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Des Moines Airport to Hilton Head Island Airport?

  • How old do you have to be to fly from Des Moines Airport to Hilton Head Island Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Hilton Head Island Airport.

  • What documentation or ID do you need to fly to Hilton Head Island Airport?

    The required travel and health documents for your Hilton Head Island Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Hilton Head Island Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Des Moines to Hilton Head Island?

Best airlines flying from Des Moines to Hilton Head Island

Compare and see reviews for airlines that fly from Des Moines to Hilton Head Island with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $258Free CancellationRating
7.2
11,201 reviews
Search American Airlines flights

Traveling to a place near Hilton Head Island?

Book flights to Hilton Head Island if you plan to visit one of these locations
Beaufort
Bluffton
Daufuskie Island

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Hilton Head Island?

It is quick and easy to find Des Moines to Hilton Head Island flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Hilton Head Island that suits you.

Can I find flights from Des Moines to Hilton Head Island with flexible booking policies on momondo?

Flights from Des Moines to Hilton Head Island with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Des Moines to Hilton Head Island?

Once all potential Des Moines to Hilton Head Island flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Des Moines to Hilton Head Island right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Hilton Head Island, momondo offers a useful price alert feature which will track prices for flights to Hilton Head Island from Des Moines and alert you when they change.

An easier way to manage your Hilton Head Island trip

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