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Cheap flights from Des Moines to Columbia from $269

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Columbia departing on 7/9. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Des Moines to Columbia

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
5:00 pm - 11:46 pm
DSM
-
CAE
5h 46m
1 stop
Delta Logo
5:35 am - 10:45 am
CAE
-
DSM
6h 10m
1 stop
$297Delta
Fri, Jul 3 - Wed, Jul 8
United Airlines Logo
11:23 am - 5:05 pm
DSM
-
CAE
4h 42m
1 stop
United Airlines Logo
10:31 am - 9:22 pm
CAE
-
DSM
11h 51m
2 stops
$302United Airlines
Sat, Jul 4 - Thu, Jul 9
United Airlines Logo
9:14 am - 9:16 pm
DSM
-
CAE
11h 02m
2 stops
United Airlines Logo
10:31 am - 9:22 pm
CAE
-
DSM
11h 51m
2 stops
$307United Airlines
Sat, Jul 4 - Thu, Jul 9
American Airlines Logo
2:22 pm - 10:38 pm
DSM
-
CAE
7h 16m
1 stop
American Airlines Logo
5:13 pm - 12:01 am
CAE
-
DSM
7h 48m
1 stop
$309American Airlines
Thu, Jul 9 - Wed, Jul 15
United Airlines Logo
6:00 am - 2:16 pm
DSM
-
CAE
7h 16m
2 stops
United Airlines Logo
10:31 am - 9:22 pm
CAE
-
DSM
11h 51m
2 stops
$319United Airlines
Thu, Jul 9 - Wed, Jul 15
Delta Logo
5:00 pm - 11:46 pm
DSM
-
CAE
5h 46m
1 stop
Delta Logo
10:10 am - 1:34 pm
CAE
-
DSM
4h 24m
1 stop
$322Delta
Fri, Jul 3 - Wed, Jul 8
American Airlines Logo
1:41 pm - 10:03 pm
DSM
-
CAE
7h 22m
1 stop
American Airlines Logo
5:13 pm - 12:01 am
CAE
-
DSM
7h 48m
1 stop
$324American Airlines
Thu, Jul 2 - Wed, Jul 8
United Airlines Logo
8:00 am - 7:09 pm
DSM
-
CAE
10h 09m
2 stops
United Airlines Logo
6:25 am - 10:17 am
CAE
-
DSM
4h 52m
1 stop
$329United Airlines
Fri, Jul 3 - Thu, Jul 9
American Airlines Logo
7:12 am - 2:42 pm
DSM
-
CAE
6h 30m
1 stop
American Airlines Logo
6:00 am - 10:00 am
CAE
-
DSM
5h 00m
1 stop
$338American Airlines
Tue, Aug 4 - Sat, Aug 8
United Airlines Logo
6:00 am - 2:16 pm
DSM
-
CAE
7h 16m
2 stops
United Airlines Logo
10:31 am - 9:22 pm
CAE
-
DSM
11h 51m
2 stops
$340United Airlines
Thu, Jul 9 - Wed, Jul 15

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American Airlines flights from Des Moines to Columbia

Our best American Airlines deals on Des Moines to Columbia flight tickets
American Airlines
Jul 3
DSM3:41 pmDes Moines
6h 52m
1 stop
CAE11:33 pmColumbia Metropolitan
Jul 8
CAE8:49 amColumbia Metropolitan
5h 07m
1 stop
DSM12:56 pmDes Moines
$312
American Airlines
Jul 2
DSM1:41 pmDes Moines
7h 22m
1 stop
CAE10:03 pmColumbia Metropolitan
Jul 8
CAE5:13 pmColumbia Metropolitan
7h 48m
1 stop
DSM12:01 amDes Moines
$324
American Airlines
Jul 28
DSM7:12 amDes Moines
6h 30m
1 stop
CAE2:42 pmColumbia Metropolitan
Aug 12
CAE6:46 pmColumbia Metropolitan
5h 58m
1 stop
DSM11:44 pmDes Moines
$338

Delta flights from Des Moines to Columbia

Our best Delta deals on Des Moines to Columbia flight tickets
Delta
Jul 3
DSM5:00 pmDes Moines
5h 46m
1 stop
CAE11:46 pmColumbia Metropolitan
Jul 8
CAE5:35 amColumbia Metropolitan
6h 10m
1 stop
DSM10:45 amDes Moines
$297
Delta
Jul 10
DSM11:30 amDes Moines
6h 19m
1 stop
CAE6:49 pmColumbia Metropolitan
Jul 13
CAE5:35 amColumbia Metropolitan
6h 10m
1 stop
DSM10:45 amDes Moines
$309
Delta
Jul 3
DSM5:00 pmDes Moines
5h 46m
1 stop
CAE11:46 pmColumbia Metropolitan
Jul 8
CAE10:10 amColumbia Metropolitan
4h 24m
1 stop
DSM1:34 pmDes Moines
$322

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Columbia that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 19, 2026.
Use the filters below to find and compare flights from Des Moines to Columbia that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesColumbia

DSM - CAE

DSMCAE

Des Moines

Fri 7/3

5:00 pm-11:46 pm

1 stop5h 46m

Columbia Metropolitan

Wed 7/8

5:35 am-10:45 am

1 stop6h 10m

$297

Des MoinesColumbia

DSM - CAE

DSMCAE

Des Moines

Sat 7/4

11:23 am-5:05 pm

1 stop4h 42m

Columbia Metropolitan

Thu 7/9

10:31 am-9:22 pm

2 stops11h 51m

$302

Des MoinesColumbia

DSM - CAE

DSMCAE

Des Moines

Sat 7/4

9:14 am-9:16 pm

2 stops11h 02m

Columbia Metropolitan

Thu 7/9

10:31 am-9:22 pm

2 stops11h 51m

$307

Des MoinesColumbia

DSM - CAE

DSMCAE

Des Moines

Thu 7/9

2:22 pm-10:38 pm

1 stop7h 16m

Columbia Metropolitan

Wed 7/15

5:13 pm-12:01 am

1 stop7h 48m

$309

Des MoinesColumbia

DSM - CAE

DSMCAE

Des Moines

Thu 7/9

6:00 am-2:16 pm

2 stops7h 16m

Columbia Metropolitan

Wed 7/15

10:31 am-9:22 pm

2 stops11h 51m

$319
Quickest round-trip

Des MoinesColumbia

DSM - CAE

DSMCAE

Des Moines

Fri 7/3

5:00 pm-11:46 pm

1 stop5h 46m

Columbia Metropolitan

Wed 7/8

10:10 am-1:34 pm

1 stop4h 24m

$322

Des MoinesColumbia

DSM - CAE

DSMCAE

Des Moines

Thu 7/2

1:41 pm-10:03 pm

1 stop7h 22m

Columbia Metropolitan

Wed 7/8

5:13 pm-12:01 am

1 stop7h 48m

$324

Des MoinesColumbia

DSM - CAE

DSMCAE

Des Moines

Fri 7/3

8:00 am-7:09 pm

2 stops10h 09m

Columbia Metropolitan

Thu 7/9

6:25 am-10:17 am

1 stop4h 52m

$329

Des MoinesColumbia

DSM - CAE

DSMCAE

Des Moines

Tue 8/4

7:12 am-2:42 pm

1 stop6h 30m

Columbia Metropolitan

Sat 8/8

6:00 am-10:00 am

1 stop5h 00m

$338

Des MoinesColumbia

DSM - CAE

DSMCAE

Des Moines

Thu 7/9

6:00 am-2:16 pm

2 stops7h 16m

Columbia Metropolitan

Wed 7/15

10:31 am-9:22 pm

2 stops11h 51m

$340

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Columbia from

How to get the cheapest flight ticket from Des Moines to Columbia

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Des Moines to Columbia Metropolitan?

American Airlines, Delta, and United Airlines are the most popular carriers operating from Des Moines to Columbia Metropolitan

What airlines fly to Columbia?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Columbia from Des Moines according to our data. American Airlines is the first choice among our users, with 76% of people opting to fly with this airline when traveling to Columbia. Keep in mind that there are 4 different airlines that fly to Columbia on a routine basis, so you have a few additional options to choose from.

When to book flights from Des Moines to Columbia

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Columbia according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Columbia (DSM to CAE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Columbia

Fastest flight time

4h 07m

Direct flights

None
The fastest flight from Des Moines to Columbia takes 4h 07m
There are no direct flights from Des Moines to Columbia. There are no popular flight routes from Des Moines to Columbia.
Search flight deals

Frequently asked questions about flying from Des Moines to Columbia

  • How far is Des Moines to Columbia Metropolitan by plane?

    There are 862.4 mi between Des Moines and Columbia Metropolitan. By plane, this route typically takes 4h 07m.

  • When did momondo last update prices for flights from Des Moines Airport to Columbia Metropolitan Airport?

    Prices for flights from Des Moines Airport to Columbia Metropolitan Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Des Moines Airport to Columbia Metropolitan Airport?

  • How old do you have to be to fly from Des Moines Airport to Columbia Metropolitan Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Columbia Metropolitan Airport.

  • What documentation or ID do you need to fly to Columbia Metropolitan Airport?

    The travel and health documents required for your trip to Columbia Metropolitan Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Columbia Metropolitan Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Des Moines to Columbia?

Best airlines flying from Des Moines to Columbia

Compare and see reviews for airlines that fly from Des Moines to Columbia with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $248Free CancellationRating
7.8
8,418 reviews
Search Delta flights
American AirlinesPriceFrom $272Free CancellationRating
7.1
11,703 reviews
Search American Airlines flights

Traveling to a place near Columbia?

Book flights to Columbia if you plan to visit one of these locations
Orangeburg
Lexington
West Columbia
Irmo
Swansea

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Columbia?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Columbia from Des Moines.

Can I find flights from Des Moines to Columbia with flexible booking policies on momondo?

All flight searches from Des Moines to Columbia on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Des Moines to Columbia?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Columbia from Des Moines.

I’m not ready to book a flight from Des Moines to Columbia right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Columbia, momondo offers a useful price alert feature which will track prices for flights to Columbia from Des Moines and alert you when they change.

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