Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Des Moines to Cleveland from $101

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Cleveland departing on 10/16. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Des Moines to Cleveland (DSM-CLE)

Cheap round-trip flights

Southwest Logo
4:35 pm - 9:10 pmDSM-CLE
3h 35m1 stop
Southwest Logo
9:00 am - 11:25 amCLE-DSM
3h 25m1 stop
$257Southwest
Find Deal
Tue, Sep 16 - Tue, Sep 23
Southwest Logo
4:35 pm - 9:10 pmDSM-CLE
3h 35m1 stop
Southwest Logo
5:35 am - 11:25 amCLE-DSM
6h 50m2 stops
$262Southwest
Find Deal
Tue, Sep 16 - Tue, Sep 23
American Airlines Logo
7:03 am - 3:39 pmDSM-CLE
7h 36m2 stops
American Airlines Logo
6:09 am - 10:45 amCLE-DSM
5h 36m1 stop
$263American Airlines
Find Deal
Tue, Sep 30 - Tue, Oct 7
Logo
10:41 am - 8:33 pmDSM-CLE
8h 52m1 stop
Logo
5:37 pm - 5:01 pmCLE-DSM
24h 24m1 stop
$265
Find Deal
Thu, Oct 16 - Sun, Oct 19
Logo
10:41 am - 6:24 pmDSM-CLE
30h 43m1 stop
Logo
5:37 pm - 5:14 pmCLE-DSM
24h 37m1 stop
$276
Find Deal
Thu, Oct 2 - Thu, Oct 9
American Airlines Logo
7:08 am - 3:39 pmDSM-CLE
7h 31m2 stops
American Airlines Logo
6:30 pm - 11:23 pmCLE-DSM
5h 53m1 stop
$280American Airlines
Find Deal
Sat, Oct 4 - Mon, Oct 6
United Airlines Logo
1:00 pm - 11:44 pmDSM-CLE
9h 44m2 stops
United Airlines Logo
6:00 am - 12:19 pmCLE-DSM
7h 19m2 stops
$337United Airlines
Find Deal
Tue, Sep 30 - Tue, Oct 7
United Airlines Logo
6:15 pm - 11:59 pmDSM-CLE
4h 44m1 stop
United Airlines Logo
6:00 am - 10:39 amCLE-DSM
5h 39m1 stop
$342United Airlines
Find Deal
Sun, Aug 31 - Thu, Sep 4
Delta Logo
3:30 pm - 10:57 pmDSM-CLE
6h 27m1 stop
Delta Logo
7:05 am - 10:07 amCLE-DSM
4h 02m1 stop
$347Delta
Find Deal
Sat, Aug 30 - Fri, Sep 5
Delta Logo
12:35 pm - 5:12 pmDSM-CLE
3h 37m1 stop
Delta Logo
5:30 am - 9:37 amCLE-DSM
5h 07m1 stop
$387Delta
Find Deal
Sat, Sep 6 - Sun, Sep 7

American Airlines flights from Des Moines to Cleveland

Our best American Airlines deals on Des Moines to Cleveland flight tickets
American Airlines
Sep 30
DSM7:03 amDes Moines
7h 36m
2 stops
CLE3:39 pmCleveland Hopkins Intl
Oct 7
CLE6:09 amCleveland Hopkins Intl
5h 36m
1 stop
DSM10:45 amDes Moines
$263
Find similar
American Airlines
Oct 4
DSM7:08 amDes Moines
7h 31m
2 stops
CLE3:39 pmCleveland Hopkins Intl
Oct 6
CLE6:30 pmCleveland Hopkins Intl
5h 53m
1 stop
DSM11:23 pmDes Moines
$280
Find similar
American Airlines
Sep 17
DSM4:09 pmDes Moines
6h 28m
1 stop
CLE11:37 pmCleveland Hopkins Intl
Sep 19
CLE6:00 amCleveland Hopkins Intl
8h 05m
1 stop
DSM1:05 pmDes Moines
$302
Find similar

Frontier flights from Des Moines to Cleveland

Our best Frontier deals on Des Moines to Cleveland flight tickets
Frontier
Oct 17
DSM2:37 pmDes Moines
10h 15m
1 stop
CLE1:52 amCleveland Hopkins Intl
Oct 19
CLE5:03 pmCleveland Hopkins Intl
21h 49m
2 stops
DSM1:52 pmDes Moines
$299
Find similar
Frontier
Oct 16
DSM2:37 pmDes Moines
20h 05m
2 stops
CLE11:42 amCleveland Hopkins Intl
Oct 19
CLE5:03 pmCleveland Hopkins Intl
21h 49m
2 stops
DSM1:52 pmDes Moines
$366
Find similar
Frontier
Aug 24
DSM3:23 pmDes Moines
26h 43m
1 stop
CLE7:06 pmCleveland Hopkins Intl
Aug 31
CLE8:11 pmCleveland Hopkins Intl
19h 12m
1 stop
DSM2:23 pmDes Moines
$470
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Cleveland that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 18, 2025.
Use the filters below to find and compare flights from Des Moines to Cleveland that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesCleveland

DSM - CLE

DSMCLE

Des Moines

Tue 9/16

4:35 pm-9:10 pm

1 stop3h 35m

Cleveland Hopkins Intl

Tue 9/23

9:00 am-11:25 am

1 stop3h 25m

$257

Des MoinesCleveland

DSM - CLE

DSMCLE

Des Moines

Tue 9/16

4:35 pm-9:10 pm

1 stop3h 35m

Cleveland Hopkins Intl

Tue 9/23

5:35 am-11:25 am

2 stops6h 50m

$262

Des MoinesCleveland

DSM - CLE

DSMCLE

Des Moines

Tue 9/30

7:03 am-3:39 pm

2 stops7h 36m

Cleveland Hopkins Intl

Tue 10/7

6:09 am-10:45 am

1 stop5h 36m

$263

Des MoinesCleveland

DSM - CLE

DSMCLE

Des Moines

Thu 10/16

10:41 am-8:33 pm

1 stop8h 52m

Cleveland Hopkins Intl

Sun 10/19

5:37 pm-5:01 pm

1 stop24h 24m

$265

Des MoinesCleveland

DSM - CLE

DSMCLE

Des Moines

Thu 10/2

10:41 am-6:24 pm

1 stop30h 43m

Cleveland Hopkins Intl

Thu 10/9

5:37 pm-5:14 pm

1 stop24h 37m

$276

Des MoinesCleveland

DSM - CLE

DSMCLE

Des Moines

Sat 10/4

7:08 am-3:39 pm

2 stops7h 31m

Cleveland Hopkins Intl

Mon 10/6

6:30 pm-11:23 pm

1 stop5h 53m

$280

Des MoinesCleveland

DSM - CLE

DSMCLE

Des Moines

Tue 9/30

1:00 pm-11:44 pm

2 stops9h 44m

Cleveland Hopkins Intl

Tue 10/7

6:00 am-12:19 pm

2 stops7h 19m

$337

Des MoinesCleveland

DSM - CLE

DSMCLE

Des Moines

Sun 8/31

6:15 pm-11:59 pm

1 stop4h 44m

Cleveland Hopkins Intl

Thu 9/4

6:00 am-10:39 am

1 stop5h 39m

$342

Des MoinesCleveland

DSM - CLE

DSMCLE

Des Moines

Sat 8/30

3:30 pm-10:57 pm

1 stop6h 27m

Cleveland Hopkins Intl

Fri 9/5

7:05 am-10:07 am

1 stop4h 02m

$347

Des MoinesCleveland

DSM - CLE

DSMCLE

Des Moines

Sat 9/6

12:35 pm-5:12 pm

1 stop3h 37m

Cleveland Hopkins Intl

Sun 9/7

5:30 am-9:37 am

1 stop5h 07m

$387

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 17 resultsSorted by cheapest first
1
2

See travel insights to Cleveland from

How to get the cheapest flight ticket from Des Moines to Cleveland

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Cleveland?

In general, April is the cheapest month to fly from Des Moines to Cleveland. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $341. If you’re not able to fly to Cleveland in April, then October is your next best option. Flight prices from Des Moines to Cleveland during October average around $356.

What is the cheapest day to depart on your flight to Cleveland?

The cheapest day to depart from Des Moines to Cleveland is on a Tuesday when prices can be found for as low as $325. Be sure to avoid booking your departure on a Monday as prices are generally higher than usual. According to our data, the average ticket price to Cleveland on Monday is $518.

What is the cheapest time of day to depart on your flight to Cleveland?

Our data shows that the cheapest Des Moines to Cleveland flights are usually those with departure times in the evening. Our users have found flights to Cleveland in the evening for as low as $192. In contrast, the most expensive time of day to depart to Cleveland is in the morning when prices are around $408.

When to book flights from Des Moines to Cleveland

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Cleveland according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Cleveland (DSM to CLE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Cleveland

Best Price Found

$101

Fastest flight time

3h 25m

Direct flights

None

Airports in Cleveland

1 airport
The best one-way flight to Cleveland from Des Moines in the past 72 hours is $101. The best round-trip flight deal from Des Moines to Cleveland found on momondo in the last 72 hours is $257.
The fastest flight from Des Moines to Cleveland takes 3h 25m
There are no direct flights from Des Moines to Cleveland. Popular non-direct route for this connection is Des Moines Airport - Cleveland Hopkins Intl Airport.
There is 1 airport near Cleveland: Cleveland Hopkins Intl (CLE)
Search flight deals

  • How far is Des Moines to Cleveland Hopkins Intl by plane?

    The distance between Des Moines and Cleveland Hopkins Intl is about 616.3 mi. Flights usually cover this in 3h 25m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Des Moines Airport to Cleveland Hopkins Intl Airport?

    Prices for flights from Des Moines Airport to Cleveland Hopkins Intl Airport were last updated today.

  • How many operators does momondo search for flights from Des Moines Airport to Cleveland Hopkins Intl Airport?

  • How old do you have to be to fly from Des Moines Airport to Cleveland Hopkins Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Cleveland Hopkins Intl Airport.

  • What documentation or ID do you need to fly to Cleveland Hopkins Intl Airport?

    The travel and health documents required for your trip to Cleveland Hopkins Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Cleveland Hopkins Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Des Moines to Cleveland?

Best airlines flying from Des Moines to Cleveland

Compare and see reviews for airlines that fly from Des Moines to Cleveland with momondo
Airline
Rating
Free Cancellation
Price
SouthwestPriceFrom $281Free CancellationRating
8.0
4,246 reviews
Search Southwest flights
American AirlinesPriceFrom $286Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
DeltaPriceFrom $316Free CancellationRating
8.0
7,981 reviews
Search Delta flights
United AirlinesPriceFrom $346Free CancellationRating
7.4
8,925 reviews
Search United Airlines flights

Traveling to a place near Cleveland?

Book flights to Cleveland if you plan to visit one of these locations
Sandusky
Beachwood
Mansfield
Geneva-on-the-Lake
Elyria
Mentor
Independence
Westlake
Wooster
Kent
Streetsboro
Willoughby
North Olmsted
Ashland
Cuyahoga Falls
Kelleys Island
Medina
Avon
Painesville
Lakewood

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Cleveland?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Des Moines to Cleveland. momondo saves you time and could save you money on your trip.

Can I find flights from Des Moines to Cleveland with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Des Moines to Cleveland flights to just show those with flexible booking policies.

How can momondo help me find flights from Des Moines to Cleveland?

momondo helps you find the best flight between Des Moines and Cleveland by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Des Moines to Cleveland right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Des Moines to Cleveland flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Cleveland trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Sat 8/23
Sat 8/30
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States