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Cheap flights from Denver to Florence from $334

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Denver to Florence departing on 6/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Find the cheapest flights from Denver to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
8:58 am - 10:00 pm
DEN
-
FLO
11h 02m
2 stops
American Airlines Logo
2:35 pm - 8:17 pm
FLO
-
DEN
7h 42m
1 stop
$334American Airlines
Tue, Jun 23 - Wed, Jul 8
American Airlines Logo
8:58 am - 10:00 pm
DEN
-
FLO
11h 02m
2 stops
American Airlines Logo
5:05 am - 5:20 pm
FLO
-
DEN
14h 15m
2 stops
$424American Airlines
Tue, Jun 23 - Tue, Jun 30
American Airlines Logo
1:57 pm - 10:00 pm
DEN
-
FLO
6h 03m
1 stop
American Airlines Logo
2:35 pm - 8:17 pm
FLO
-
DEN
7h 42m
1 stop
$474American Airlines
Tue, Jun 23 - Wed, Jul 8
American Airlines Logo
8:58 am - 10:00 pm
DEN
-
FLO
11h 02m
2 stops
American Airlines Logo
5:17 am - 9:10 am
FLO
-
DEN
5h 53m
1 stop
$479American Airlines
Tue, Jun 23 - Tue, Jul 7
American Airlines Logo
8:58 am - 10:00 pm
DEN
-
FLO
11h 02m
2 stops
American Airlines Logo
2:35 pm - 9:32 pm
FLO
-
DEN
8h 57m
2 stops
$484American Airlines
Tue, Jun 23 - Wed, Jul 8
American Airlines Logo
6:38 am - 2:10 pm
DEN
-
FLO
5h 32m
1 stop
American Airlines Logo
5:05 am - 4:45 pm
FLO
-
DEN
13h 40m
2 stops
$495American Airlines
Sat, May 23 - Mon, May 25
American Airlines Logo
6:38 am - 2:10 pm
DEN
-
FLO
5h 32m
1 stop
American Airlines Logo
2:35 pm - 8:13 pm
FLO
-
DEN
7h 38m
1 stop
$571American Airlines
Sat, May 23 - Mon, May 25
American Airlines Logo
6:38 am - 2:10 pm
DEN
-
FLO
5h 32m
1 stop
American Airlines Logo
2:35 pm - 11:55 pm
FLO
-
DEN
11h 20m
2 stops
$576American Airlines
Wed, Jun 3 - Thu, Jun 11
American Airlines Logo
6:55 am - 10:00 pm
DEN
-
FLO
13h 05m
2 stops
American Airlines Logo
5:05 am - 4:45 pm
FLO
-
DEN
13h 40m
2 stops
$592American Airlines
Sat, May 23 - Mon, May 25
American Airlines Logo
1:57 pm - 10:00 pm
DEN
-
FLO
6h 03m
1 stop
American Airlines Logo
5:17 am - 9:10 am
FLO
-
DEN
5h 53m
1 stop
$619American Airlines
Tue, Jun 23 - Tue, Jul 7

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American Airlines flights from Denver to Florence, South Carolina

Our best American Airlines deals on Denver to Florence, South Carolina flight tickets
American Airlines
Jun 23
DEN8:58 amDenver Intl
11h 02m
2 stops
FLO10:00 pmFlorence
Jul 8
FLO2:35 pmFlorence
7h 42m
1 stop
DEN8:17 pmDenver Intl
$334
American Airlines
Jun 23
DEN8:58 amDenver Intl
11h 02m
2 stops
FLO10:00 pmFlorence
Jun 30
FLO5:05 amFlorence
14h 15m
2 stops
DEN5:20 pmDenver Intl
$424
American Airlines
Jun 23
DEN1:57 pmDenver Intl
6h 03m
1 stop
FLO10:00 pmFlorence
Jul 8
FLO2:35 pmFlorence
7h 42m
1 stop
DEN8:17 pmDenver Intl
$474

momondo Fare Finder

 
Customize your flight search to find flights from Denver to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 21, 2026.
Use the filters below to find and compare flights from Denver to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DenverFlorence

DEN - FLO

DENFLO

Denver Intl

Tue 6/23

8:58 am-10:00 pm

2 stops11h 02m

Florence

Wed 7/8

2:35 pm-8:17 pm

1 stop7h 42m

$334

DenverFlorence

DEN - FLO

DENFLO

Denver Intl

Tue 6/23

8:58 am-10:00 pm

2 stops11h 02m

Florence

Tue 6/30

5:05 am-5:20 pm

2 stops14h 15m

$424

DenverFlorence

DEN - FLO

DENFLO

Denver Intl

Tue 6/23

1:57 pm-10:00 pm

1 stop6h 03m

Florence

Wed 7/8

2:35 pm-8:17 pm

1 stop7h 42m

$474

DenverFlorence

DEN - FLO

DENFLO

Denver Intl

Tue 6/23

8:58 am-10:00 pm

2 stops11h 02m

Florence

Tue 7/7

5:17 am-9:10 am

1 stop5h 53m

$479

DenverFlorence

DEN - FLO

DENFLO

Denver Intl

Tue 6/23

8:58 am-10:00 pm

2 stops11h 02m

Florence

Wed 7/8

2:35 pm-9:32 pm

2 stops8h 57m

$484

DenverFlorence

DEN - FLO

DENFLO

Denver Intl

Sat 5/23

6:38 am-2:10 pm

1 stop5h 32m

Florence

Mon 5/25

5:05 am-4:45 pm

2 stops13h 40m

$495

DenverFlorence

DEN - FLO

DENFLO

Denver Intl

Sat 5/23

6:38 am-2:10 pm

1 stop5h 32m

Florence

Mon 5/25

2:35 pm-8:13 pm

1 stop7h 38m

$571

DenverFlorence

DEN - FLO

DENFLO

Denver Intl

Wed 6/3

6:38 am-2:10 pm

1 stop5h 32m

Florence

Thu 6/11

2:35 pm-11:55 pm

2 stops11h 20m

$576

DenverFlorence

DEN - FLO

DENFLO

Denver Intl

Sat 5/23

6:55 am-10:00 pm

2 stops13h 05m

Florence

Mon 5/25

5:05 am-4:45 pm

2 stops13h 40m

$592
Quickest round-trip

DenverFlorence

DEN - FLO

DENFLO

Denver Intl

Tue 6/23

1:57 pm-10:00 pm

1 stop6h 03m

Florence

Tue 7/7

5:17 am-9:10 am

1 stop5h 53m

$619

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Florence from

How to get the cheapest flight ticket from Denver to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What airlines fly to Florence, South Carolina?

American Airlines, Frontier and United Airlines are the top three most popular airlines that fly to Florence, South Carolina from Denver according to our data. American Airlines is the first choice among our users, with 43% of people opting to fly with this airline when traveling to Florence, South Carolina. Keep in mind that there are 6 different airlines that fly to Florence, South Carolina on a routine basis, so you have a few additional options to choose from.

When to book flights from Denver to Florence, South Carolina

Are you open to changing your travel dates? Check out the ideal times to fly from Denver to Florence, South Carolina according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Denver to Florence, South Carolina (DEN to FLO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Denver to Florence, South Carolina

Fastest flight time

5h 32m

Direct flights

None
The fastest flight from Denver to Florence, South Carolina takes 5h 32m
There are no direct flights from Denver to Florence, South Carolina. There are no popular flight routes from Denver to Florence, South Carolina.
Search flight deals

Frequently asked questions about flying from Denver to Florence, South Carolina

  • How far is Denver Intl to Florence by plane?

    The straight-line distance from Denver Intl to Florence is 1437.7 mi. In terms of flight time, this usually takes a little over 5h 32m.

  • When did momondo last update prices for flights from Denver Intl Airport to Florence Airport?

    Prices for flights from Denver Intl Airport to Florence Airport refresh daily.

  • How old do you have to be to fly from Denver Intl Airport to Florence Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Denver Intl Airport to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The required travel and health documents for your Florence Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florence Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Lake City
Darlington
Bennettsville

Why use momondo?

Why should I use momondo to find a flight deal from Denver to Florence?

Finding the right flight to Florence from Denver is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Florence quick and easy, saving you time and money.

Can I find flights from Denver to Florence with flexible booking policies on momondo?

momondo does allow users to show only those flights to Florence from Denver which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Denver to Florence?

momondo helps you find the best flight between Denver and Florence by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Denver to Florence right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Denver to Florence flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Florence, South Carolina trip

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