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Cheap flights from Denver to Florence from $500

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Denver to Florence departing on 3/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Denver to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
7:00 am - 11:57 pm
DEN
-
FLO
14h 57m
2 stops
American Airlines Logo
6:25 pm - 10:42 pm
FLO
-
DEN
6h 17m
1 stop
$657American Airlines
Sat, Mar 21 - Sat, Mar 28
American Airlines Logo
7:00 am - 11:57 pm
DEN
-
FLO
14h 57m
2 stops
American Airlines Logo
5:16 am - 11:36 am
FLO
-
DEN
8h 20m
2 stops
$662American Airlines
Sat, Mar 21 - Sat, Mar 28
American Airlines Logo
6:39 am - 5:50 pm
DEN
-
FLO
9h 11m
1 stop
American Airlines Logo
5:16 am - 1:24 pm
FLO
-
DEN
10h 08m
1 stop
$674American Airlines
Sat, Mar 21 - Sat, Mar 28
American Airlines Logo
8:07 am - 5:50 pm
DEN
-
FLO
7h 43m
1 stop
American Airlines Logo
5:16 am - 1:57 pm
FLO
-
DEN
10h 41m
2 stops
$692American Airlines
Sat, Mar 21 - Sat, Mar 28
American Airlines Logo
4:03 pm - 11:57 pm
DEN
-
FLO
5h 54m
1 stop
American Airlines Logo
6:25 pm - 10:42 pm
FLO
-
DEN
6h 17m
1 stop
$707American Airlines
Sat, Mar 21 - Sat, Mar 28
American Airlines Logo
7:00 am - 11:57 pm
DEN
-
FLO
14h 57m
2 stops
American Airlines Logo
5:16 am - 5:50 pm
FLO
-
DEN
14h 34m
2 stops
$751American Airlines
Sat, Mar 21 - Sat, Mar 28
American Airlines Logo
4:03 pm - 11:57 pm
DEN
-
FLO
5h 54m
1 stop
American Airlines Logo
6:20 pm - 8:47 am
FLO
-
DEN
16h 27m
2 stops
$811American Airlines
Mon, Mar 16 - Fri, Mar 20
American Airlines Logo
4:03 pm - 11:57 pm
DEN
-
FLO
5h 54m
1 stop
American Airlines Logo
6:20 pm - 10:51 am
FLO
-
DEN
18h 31m
1 stop
$819American Airlines
Mon, Mar 16 - Fri, Mar 20
American Airlines Logo
7:00 am - 11:57 pm
DEN
-
FLO
14h 57m
2 stops
American Airlines Logo
5:16 am - 5:17 pm
FLO
-
DEN
14h 01m
2 stops
$823American Airlines
Mon, Mar 16 - Fri, Mar 20

American Airlines flights from Denver to Florence, South Carolina

Our best American Airlines deals on Denver to Florence, South Carolina flight tickets
American Airlines
Mar 21
DEN7:00 amDenver Intl
14h 57m
2 stops
FLO11:57 pmFlorence
Mar 28
FLO6:25 pmFlorence
6h 17m
1 stop
DEN10:42 pmDenver Intl
$657
American Airlines
Mar 21
DEN7:00 amDenver Intl
14h 57m
2 stops
FLO11:57 pmFlorence
Mar 28
FLO5:16 amFlorence
8h 20m
2 stops
DEN11:36 amDenver Intl
$662
American Airlines
Mar 21
DEN6:39 amDenver Intl
9h 11m
1 stop
FLO5:50 pmFlorence
Mar 28
FLO5:16 amFlorence
10h 08m
1 stop
DEN1:24 pmDenver Intl
$674

momondo Fare Finder

 
Customize your flight search to find flights from Denver to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 5, 2026.
Use the filters below to find and compare flights from Denver to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DenverFlorence

DEN - FLO

DENFLO

Denver Intl

Sat 3/21

7:00 am-11:57 pm

2 stops14h 57m

Florence

Sat 3/28

6:25 pm-10:42 pm

1 stop6h 17m

$657

DenverFlorence

DEN - FLO

DENFLO

Denver Intl

Sat 3/21

7:00 am-11:57 pm

2 stops14h 57m

Florence

Sat 3/28

5:16 am-11:36 am

2 stops8h 20m

$662

DenverFlorence

DEN - FLO

DENFLO

Denver Intl

Sat 3/21

6:39 am-5:50 pm

1 stop9h 11m

Florence

Sat 3/28

5:16 am-1:24 pm

1 stop10h 08m

$674

DenverFlorence

DEN - FLO

DENFLO

Denver Intl

Sat 3/21

8:07 am-5:50 pm

1 stop7h 43m

Florence

Sat 3/28

5:16 am-1:57 pm

2 stops10h 41m

$692
Quickest round-trip

DenverFlorence

DEN - FLO

DENFLO

Denver Intl

Sat 3/21

4:03 pm-11:57 pm

1 stop5h 54m

Florence

Sat 3/28

6:25 pm-10:42 pm

1 stop6h 17m

$707

DenverFlorence

DEN - FLO

DENFLO

Denver Intl

Sat 3/21

7:00 am-11:57 pm

2 stops14h 57m

Florence

Sat 3/28

5:16 am-5:50 pm

2 stops14h 34m

$751

DenverFlorence

DEN - FLO

DENFLO

Denver Intl

Mon 3/16

4:03 pm-11:57 pm

1 stop5h 54m

Florence

Fri 3/20

6:20 pm-8:47 am

2 stops16h 27m

$811

DenverFlorence

DEN - FLO

DENFLO

Denver Intl

Mon 3/16

4:03 pm-11:57 pm

1 stop5h 54m

Florence

Fri 3/20

6:20 pm-10:51 am

1 stop18h 31m

$819

DenverFlorence

DEN - FLO

DENFLO

Denver Intl

Mon 3/16

7:00 am-11:57 pm

2 stops14h 57m

Florence

Fri 3/20

5:16 am-5:17 pm

2 stops14h 01m

$823
Cheapest one-way
Quickest one-way

DenverFlorence

DEN - FLO

DENFLO

Denver Intl

Tue 3/10

1:25 pm-11:08 pm

1 stop7h 43m

$500

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
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See travel insights to Florence from

How to get the cheapest flight ticket from Denver to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Denver Intl to Florence?

American Airlines is the most popular carrier operating from Denver Intl to Florence

What airlines fly to Florence, South Carolina?

American Airlines, Frontier and United Airlines are the top three most popular airlines that fly to Florence, South Carolina from Denver according to our data. American Airlines is the first choice among our users, with 43% of people opting to fly with this airline when traveling to Florence, South Carolina. Keep in mind that there are 6 different airlines that fly to Florence, South Carolina on a routine basis, so you have a few additional options to choose from.

When to book flights from Denver to Florence, South Carolina

Are you open to changing your travel dates? Check out the ideal times to fly from Denver to Florence, South Carolina according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Denver to Florence, South Carolina (DEN to FLO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Denver to Florence, South Carolina

Fastest flight time

14h 57m

Direct flights

None
The fastest flight from Denver to Florence, South Carolina takes 14h 57m
There are no direct flights from Denver to Florence, South Carolina. There are no popular flight routes from Denver to Florence, South Carolina.
Search flight deals

  • How far is Denver Intl to Florence by plane?

    The straight-line distance from Denver Intl to Florence is 1437.7 mi. In terms of flight time, this usually takes a little over 14h 57m.

  • When did momondo last update prices for flights from Denver Intl Airport to Florence Airport?

    Prices for flights from Denver Intl Airport to Florence Airport refresh daily.

  • How old do you have to be to fly from Denver Intl Airport to Florence Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Denver Intl Airport to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The required travel and health documents for your Florence Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florence Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Lake City
Bennettsville
Darlington

Why use momondo?

Why should I use momondo to find a flight deal from Denver to Florence?

Finding the right flight to Florence from Denver is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Florence quick and easy, saving you time and money.

Can I find flights from Denver to Florence with flexible booking policies on momondo?

momondo does allow users to show only those flights to Florence from Denver which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Denver to Florence?

momondo helps you find the best flight between Denver and Florence by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Denver to Florence right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Denver to Florence flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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