What is the cheapest airline that flies from Columbus to Des Moines?

Delta, United Airlines, and American Airlines are the most popular carriers operating from Columbus to Des Moines

What airlines fly to Des Moines?

American Airlines, United Airlines and Delta are the top three most popular airlines that fly to Des Moines from Columbus according to our data. American Airlines is the first choice among our users, with 34% of people opting to fly with this airline when traveling to Des Moines. Keep in mind that there are 4 different airlines that fly to Des Moines on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Columbus to Des Moines Airport?

Prices for flights from Columbus to Des Moines Airport are updated daily.

How many operators does momondo search for flights from Columbus to Des Moines Airport?

As of November 2025, there are 4 operators available to choose from for flights from Columbus to Des Moines Airport.

How old do you have to be to fly from Columbus to Des Moines Airport?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Columbus to Des Moines Airport.

What documentation or ID do you need to fly to Des Moines Airport?

The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$129 Cheap Flights from Columbus to Des Moines in 2025/26

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Find the cheapest flights from Columbus to Des Moines

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

8:29 am - 12:48 pmCMH-DSM

5h 19m1 stop

6:40 am - 2:35 pmDSM-CMH

6h 55m1 stop

$312American Airlines

Find Deal

Sun, Dec 21 - Thu, Dec 25

6:05 am - 2:33 pmCMH-DSM

9h 28m2 stops

6:46 pm - 11:44 pmDSM-CMH

3h 58m1 stop

$317United Airlines

Find Deal

Thu, Dec 25 - Mon, Dec 29

4:17 pm - 11:58 pmCMH-DSM

8h 41m1 stop

11:15 am - 4:41 pmDSM-CMH

4h 26m1 stop

$327United Airlines

Find Deal

Wed, Dec 24 - Thu, Dec 25

9:55 am - 4:28 pmCMH-DSM

7h 33m1 stop

11:01 am - 6:24 pmDSM-CMH

6h 23m1 stop

$352Delta

Find Deal

Fri, Nov 28 - Tue, Dec 2

7:52 pm - 11:30 pmCMH-DSM

4h 38m1 stop

6:40 am - 2:35 pmDSM-CMH

6h 55m1 stop

$362American Airlines

Find Deal

Sun, Dec 28 - Tue, Dec 30

11:13 am - 4:29 pmCMH-DSM

6h 16m1 stop

4:00 pm - 11:17 pmDSM-CMH

6h 17m1 stop

$367Delta

Find Deal

Thu, Mar 5 - Mon, Mar 9

6:25 am - 11:00 amCMH-DSM

5h 35m2 stops

5:30 am - 10:15 amDSM-CMH

3h 45m1 stop

$372Southwest

Find Deal

Sun, Dec 14 - Sun, Dec 21

6:43 am - 10:21 amCMH-DSM

4h 38m1 stop

6:33 pm - 12:14 amDSM-CMH

4h 41m1 stop

$377Delta

Find Deal

Mon, Dec 8 - Mon, Dec 15

6:25 am - 11:00 amCMH-DSM

5h 35m2 stops

5:30 am - 4:05 pmDSM-CMH

9h 35m2 stops

$383Southwest

Find Deal

Sun, Dec 14 - Sun, Dec 21

6:43 am - 10:21 amCMH-DSM

4h 38m1 stop

5:34 am - 12:37 pmDSM-CMH

6h 03m1 stop

$387Delta

Find Deal

Thu, Dec 11 - Sun, Dec 14

American Airlines flights from Columbus to Des Moines

Our best American Airlines deals on Columbus to Des Moines flight tickets

American Airlines

Dec 21

CMH8:29 amColumbus

5h 19m

1 stop

DSM12:48 pmDes Moines

Dec 25

DSM6:40 amDes Moines

6h 55m

1 stop

CMH2:35 pmColumbus

$312

Find similar

American Airlines

Dec 28

CMH7:52 pmColumbus

4h 38m

1 stop

DSM11:30 pmDes Moines

Dec 30

DSM6:40 amDes Moines

6h 55m

1 stop

CMH2:35 pmColumbus

$362

Find similar

American Airlines

Nov 17

CMH5:08 pmColumbus

6h 51m

1 stop

DSM10:59 pmDes Moines

Nov 22

DSM8:51 amDes Moines

10h 30m

1 stop

CMH8:21 pmColumbus

$747

Find similar

United Airlines flights from Columbus to Des Moines

Our best United Airlines deals on Columbus to Des Moines flight tickets

United Airlines

Dec 24

CMH4:17 pmColumbus

8h 41m

1 stop

DSM11:58 pmDes Moines

Dec 25

DSM11:15 amDes Moines

4h 26m

1 stop

CMH4:41 pmColumbus

$327

Find similar

United Airlines

Nov 28

CMH7:52 amColumbus

10h 33m

2 stops

DSM5:25 pmDes Moines

Dec 2

DSM3:17 pmDes Moines

3h 54m

1 stop

CMH8:11 pmColumbus

$426

Find similar

United Airlines

Dec 21

CMH5:40 amColumbus

6h 10m

1 stop

DSM10:50 amDes Moines

Dec 25

DSM3:14 pmDes Moines

7h 30m

2 stops

CMH11:44 pmColumbus

$442

Find similar

Fly from

Fly to

Route

Depart

Return

Price

ColumbusDes Moines

CMH - DSM

CMHDSM

Columbus

Sun 12/21

8:29 am-12:48 pm

1 stop5h 19m

Des Moines

Thu 12/25

6:40 am-2:35 pm

1 stop6h 55m

$312

ColumbusDes Moines

CMH - DSM

CMHDSM

Columbus

Thu 12/25

6:05 am-2:33 pm

2 stops9h 28m

Des Moines

Mon 12/29

6:46 pm-11:44 pm

1 stop3h 58m

$317

ColumbusDes Moines

CMH - DSM

CMHDSM

Columbus

Wed 12/24

4:17 pm-11:58 pm

1 stop8h 41m

Des Moines

Thu 12/25

11:15 am-4:41 pm

1 stop4h 26m

$327

ColumbusDes Moines

CMH - DSM

CMHDSM

Columbus

Fri 11/28

9:55 am-4:28 pm

1 stop7h 33m

Des Moines

Tue 12/2

11:01 am-6:24 pm

1 stop6h 23m

$352

ColumbusDes Moines

CMH - DSM

CMHDSM

Columbus

Sun 12/28

7:52 pm-11:30 pm

1 stop4h 38m

Des Moines

Tue 12/30

6:40 am-2:35 pm

1 stop6h 55m

$362

ColumbusDes Moines

CMH - DSM

CMHDSM

Columbus

Thu 3/5

11:13 am-4:29 pm

1 stop6h 16m

Des Moines

Mon 3/9

4:00 pm-11:17 pm

1 stop6h 17m

$367

ColumbusDes Moines

CMH - DSM

CMHDSM

Columbus

Sun 12/14

6:25 am-11:00 am

2 stops5h 35m

Des Moines

Sun 12/21

5:30 am-10:15 am

1 stop3h 45m

$372

ColumbusDes Moines

CMH - DSM

CMHDSM

Columbus

Mon 12/8

6:43 am-10:21 am

1 stop4h 38m

Des Moines

Mon 12/15

6:33 pm-12:14 am

1 stop4h 41m

$377

ColumbusDes Moines

CMH - DSM

CMHDSM

Columbus

Sun 12/14

6:25 am-11:00 am

2 stops5h 35m

Des Moines

Sun 12/21

5:30 am-4:05 pm

2 stops9h 35m

$383

ColumbusDes Moines

CMH - DSM

CMHDSM

Columbus

Thu 12/11

6:43 am-10:21 am

1 stop4h 38m

Des Moines

Sun 12/14

5:34 am-12:37 pm

1 stop6h 03m

$387

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first

How to get the cheapest flight ticket from Columbus to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in November, then May is your next best option. Flight prices from Columbus to Des Moines during May average around $303.

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Columbus to Des Moines is on a Saturday. Travelers who choose to depart for Des Moines on a Saturday will often find tickets for as low as $340. Flights from Columbus to Des Moines on a Thursday will generally be more expensive and average around $509. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is at noon. momondo users have found flights departing from Columbus to Des Moines at noon for as low as $346. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the afternoon because they tend to be around $446. Of course, these prices can vary depending on the time of year and what airport you fly to.

Cheap Columbus to Des Moines flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Columbus to Des Moines

Direct flights	None

There are no direct flights from Columbus to Des Moines. There are no popular flight routes from Columbus to Des Moines.

Search flight deals

How far is Columbus to Des Moines by plane?
A flight from Columbus to Des Moines will travel around 566.8 mi. 3h 25m is a normal flight duration for this route.
When did momondo last update prices for flights from Columbus to Des Moines Airport?
Prices for flights from Columbus to Des Moines Airport are updated daily.
How many operators does momondo search for flights from Columbus to Des Moines Airport?
As of November 2025, there are 4 operators available to choose from for flights from Columbus to Des Moines Airport.
How old do you have to be to fly from Columbus to Des Moines Airport?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Columbus to Des Moines Airport.
What documentation or ID do you need to fly to Des Moines Airport?
The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Columbus to Des Moines

Compare and see reviews for airlines that fly from Columbus to Des Moines with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $216	Free Cancellation	Rating 7.9 8,007 reviews	Search Delta flights
American Airlines	PriceFrom $236	Free Cancellation	Rating 7.2 11,050 reviews	Search American Airlines flights
United Airlines	PriceFrom $243	Free Cancellation	Rating 7.4 9,015 reviews	Search United Airlines flights
Southwest	PriceFrom $286	Free Cancellation	Rating 8.0 4,244 reviews	Search Southwest flights

West Des Moines

Ames

Ankeny

Altoona

Urbandale

Clive

Newton

Pella

Johnston

Osceola

Boone

Norwalk

Grinnell

Oskaloosa

Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Columbus to Des Moines?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Columbus to Des Moines. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Columbus to Des Moines with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Des Moines from Columbus with this policy.

How can momondo help me find flights from Columbus to Des Moines?

momondo provides multiple filters to help you find the best flight to Des Moines from Columbus. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Columbus to Des Moines right now. Can momondo alert me if prices change?

Price alerts on flights to Des Moines from Columbus are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.