What airlines fly to Des Moines?

American Airlines, United Airlines and Delta are the top three most popular airlines that fly to Des Moines from Columbus according to our data. American Airlines is the first choice among our users, with 34% of people opting to fly with this airline when traveling to Des Moines. Keep in mind that there are 4 different airlines that fly to Des Moines on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Columbus to Des Moines Airport?

Prices for flights from Columbus to Des Moines Airport are updated daily.

How many operators does momondo search for flights from Columbus to Des Moines Airport?

As of September 2025, there are 4 operators available to choose from for flights from Columbus to Des Moines Airport.

How old do you have to be to fly from Columbus to Des Moines Airport?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Columbus to Des Moines Airport.

What documentation or ID do you need to fly to Des Moines Airport?

The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$174 Cheap Flights from Columbus to Des Moines in 2025/26

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Find the cheapest flights from Columbus to Des Moines

Round-trip

One-way

Last minute

Cheap round-trip flights

7:16 pm - 8:30 amCMH-DSM

14h 14m1 stop

10:41 am - 11:58 amDSM-CMH

24h 17m1 stop

$288Multiple Airlines

Find Deal

Thu, Oct 2 - Sun, Oct 5

12:31 pm - 8:29 amCMH-DSM

20h 58m1 stop

10:41 am - 11:58 amDSM-CMH

24h 17m1 stop

$289Multiple Airlines

Find Deal

Fri, Oct 3 - Sun, Oct 5

7:00 am - 10:26 amCMH-DSM

4h 26m1 stop

6:05 am - 11:11 amDSM-CMH

4h 06m1 stop

$292Delta

Find Deal

Fri, Oct 24 - Sat, Oct 25

8:55 pm - 11:30 pmCMH-DSM

3h 35m1 stop

6:15 pm - 10:35 pmDSM-CMH

3h 20m1 stop

$312Southwest

Find Deal

Mon, Oct 20 - Fri, Oct 24

7:00 am - 11:25 amCMH-DSM

5h 25m2 stops

5:45 am - 10:15 amDSM-CMH

3h 30m1 stop

$317Southwest

Find Deal

Tue, Nov 18 - Sun, Nov 23

7:00 am - 10:26 amCMH-DSM

4h 26m1 stop

5:15 pm - 10:47 pmDSM-CMH

4h 32m1 stop

$328Delta

Find Deal

Fri, Oct 24 - Sat, Oct 25

1:17 pm - 5:42 pmCMH-DSM

5h 25m1 stop

5:00 am - 9:35 amDSM-CMH

3h 35m1 stop

$332American Airlines

Find Deal

Thu, Oct 16 - Sun, Oct 19

5:05 pm - 10:56 pmCMH-DSM

6h 51m1 stop

5:00 am - 9:35 amDSM-CMH

3h 35m1 stop

$347American Airlines

Find Deal

Fri, Oct 17 - Sun, Oct 19

11:15 am - 2:23 pmCMH-DSM

4h 08m1 stop

11:31 am - 9:05 pmDSM-CMH

8h 34m2 stops

$367United Airlines

Find Deal

Fri, Oct 24 - Sat, Oct 25

7:00 am - 12:14 pmCMH-DSM

6h 14m1 stop

5:45 am - 3:22 pmDSM-CMH

8h 37m2 stops

$422United Airlines

Find Deal

Fri, Nov 7 - Sun, Nov 9

Delta flights from Columbus to Des Moines

Our best Delta deals on Columbus to Des Moines flight tickets

Delta

Oct 24

CMH7:00 amColumbus

4h 26m

1 stop

DSM10:26 amDes Moines

Oct 25

DSM6:05 amDes Moines

4h 06m

1 stop

CMH11:11 amColumbus

$292

Find similar

Delta

Oct 24

CMH7:00 amColumbus

4h 26m

1 stop

DSM10:26 amDes Moines

Oct 25

DSM5:15 pmDes Moines

4h 32m

1 stop

CMH10:47 pmColumbus

$328

Find similar

Delta

Sep 30

CMH6:08 amColumbus

4h 32m

1 stop

DSM9:40 amDes Moines

Oct 4

DSM6:00 amDes Moines

4h 24m

1 stop

CMH11:24 amColumbus

$427

Find similar

United Airlines flights from Columbus to Des Moines

Our best United Airlines deals on Columbus to Des Moines flight tickets

United Airlines

Oct 24

CMH11:15 amColumbus

4h 08m

1 stop

DSM2:23 pmDes Moines

Oct 25

DSM11:31 amDes Moines

8h 34m

2 stops

CMH9:05 pmColumbus

$367

Find similar

United Airlines

Nov 7

CMH7:00 amColumbus

6h 14m

1 stop

DSM12:14 pmDes Moines

Nov 9

DSM5:45 amDes Moines

8h 37m

2 stops

CMH3:22 pmColumbus

$422

Find similar

United Airlines

Sep 30

CMH2:17 pmColumbus

4h 07m

1 stop

DSM5:24 pmDes Moines

Oct 4

DSM3:25 pmDes Moines

7h 14m

2 stops

CMH11:39 pmColumbus

$502

Find similar

Fly from

Fly to

Route

Depart

Return

Price

ColumbusDes Moines

CMH - DSM

CMHDSM

Columbus

Thu 10/2

7:16 pm-8:30 am

1 stop14h 14m

Des Moines

Sun 10/5

10:41 am-11:58 am

1 stop24h 17m

$288

ColumbusDes Moines

CMH - DSM

CMHDSM

Columbus

Fri 10/3

12:31 pm-8:29 am

1 stop20h 58m

Des Moines

Sun 10/5

10:41 am-11:58 am

1 stop24h 17m

$289

ColumbusDes Moines

CMH - DSM

CMHDSM

Columbus

Fri 10/24

7:00 am-10:26 am

1 stop4h 26m

Des Moines

Sat 10/25

6:05 am-11:11 am

1 stop4h 06m

$292

ColumbusDes Moines

CMH - DSM

CMHDSM

Columbus

Mon 10/20

8:55 pm-11:30 pm

1 stop3h 35m

Des Moines

Fri 10/24

6:15 pm-10:35 pm

1 stop3h 20m

$312

ColumbusDes Moines

CMH - DSM

CMHDSM

Columbus

Tue 11/18

7:00 am-11:25 am

2 stops5h 25m

Des Moines

Sun 11/23

5:45 am-10:15 am

1 stop3h 30m

$317

ColumbusDes Moines

CMH - DSM

CMHDSM

Columbus

Fri 10/24

7:00 am-10:26 am

1 stop4h 26m

Des Moines

Sat 10/25

5:15 pm-10:47 pm

1 stop4h 32m

$328

ColumbusDes Moines

CMH - DSM

CMHDSM

Columbus

Thu 10/16

1:17 pm-5:42 pm

1 stop5h 25m

Des Moines

Sun 10/19

5:00 am-9:35 am

1 stop3h 35m

$332

ColumbusDes Moines

CMH - DSM

CMHDSM

Columbus

Fri 10/17

5:05 pm-10:56 pm

1 stop6h 51m

Des Moines

Sun 10/19

5:00 am-9:35 am

1 stop3h 35m

$347

ColumbusDes Moines

CMH - DSM

CMHDSM

Columbus

Fri 10/24

11:15 am-2:23 pm

1 stop4h 08m

Des Moines

Sat 10/25

11:31 am-9:05 pm

2 stops8h 34m

$367

ColumbusDes Moines

CMH - DSM

CMHDSM

Columbus

Fri 11/7

7:00 am-12:14 pm

1 stop6h 14m

Des Moines

Sun 11/9

5:45 am-3:22 pm

2 stops8h 37m

$422

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first

How to get the cheapest flight ticket from Columbus to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Columbus to Des Moines is on a Saturday. Travelers who choose to depart for Des Moines on a Saturday will often find tickets for as low as $340. Flights from Columbus to Des Moines on a Thursday will generally be more expensive and average around $509. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is at noon. momondo users have found flights departing from Columbus to Des Moines at noon for as low as $346. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the afternoon because they tend to be around $446. Of course, these prices can vary depending on the time of year and what airport you fly to.

Cheap Columbus to Des Moines flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Columbus to Des Moines

Direct flights	None

There are no direct flights from Columbus to Des Moines. There are no popular flight routes from Columbus to Des Moines.

Search flight deals

How far is Columbus to Des Moines by plane?
A flight from Columbus to Des Moines will travel around 566.8 mi. 3h 25m is a normal flight duration for this route.
When did momondo last update prices for flights from Columbus to Des Moines Airport?
Prices for flights from Columbus to Des Moines Airport are updated daily.
How many operators does momondo search for flights from Columbus to Des Moines Airport?
As of September 2025, there are 4 operators available to choose from for flights from Columbus to Des Moines Airport.
How old do you have to be to fly from Columbus to Des Moines Airport?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Columbus to Des Moines Airport.
What documentation or ID do you need to fly to Des Moines Airport?
The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Columbus to Des Moines

Compare and see reviews for airlines that fly from Columbus to Des Moines with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $216	Free Cancellation	Rating 7.9 7,961 reviews	Search Delta flights
American Airlines	PriceFrom $236	Free Cancellation	Rating 7.2 10,000 reviews	Search American Airlines flights
United Airlines	PriceFrom $243	Free Cancellation	Rating 7.4 8,926 reviews	Search United Airlines flights
Southwest	PriceFrom $286	Free Cancellation	Rating 8.0 4,242 reviews	Search Southwest flights

West Des Moines

Ames

Ankeny

Altoona

Clive

Urbandale

Pella

Newton

Osceola

Johnston

Boone

Norwalk

Grinnell

Oskaloosa

Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Columbus to Des Moines?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Columbus to Des Moines. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Columbus to Des Moines with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Des Moines from Columbus with this policy.

How can momondo help me find flights from Columbus to Des Moines?

momondo provides multiple filters to help you find the best flight to Des Moines from Columbus. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Columbus to Des Moines right now. Can momondo alert me if prices change?

Price alerts on flights to Des Moines from Columbus are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.