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Cheap flights from Columbus to Des Moines from $111

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Columbus to Des Moines departing on 9/16. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Columbus to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
6:25 am - 9:38 am
CMH
-
DSM
4h 13m
1 stop
Delta Logo
4:00 pm - 11:14 pm
DSM
-
CMH
6h 14m
1 stop
$221Delta
Wed, Oct 14 - Sat, Oct 17
American Airlines Logo
5:31 am - 9:56 am
CMH
-
DSM
5h 25m
1 stop
American Airlines Logo
6:55 am - 1:52 pm
DSM
-
CMH
5h 57m
1 stop
$222American Airlines
Thu, Aug 6 - Wed, Aug 12
United Airlines Logo
3:15 pm - 9:23 pm
CMH
-
DSM
7h 08m
2 stops
United Airlines Logo
6:29 am - 11:40 am
DSM
-
CMH
4h 11m
1 stop
$226United Airlines
Tue, Sep 1 - Thu, Sep 10
United Airlines Logo
11:05 am - 2:16 pm
CMH
-
DSM
4h 11m
1 stop
United Airlines Logo
3:20 pm - 11:44 pm
DSM
-
CMH
7h 24m
2 stops
$241United Airlines
Wed, Aug 12 - Mon, Aug 31
United Airlines Logo
7:17 am - 10:31 am
CMH
-
DSM
4h 14m
1 stop
United Airlines Logo
6:55 pm - 11:54 pm
DSM
-
CMH
3h 59m
1 stop
$245United Airlines
Fri, Sep 25 - Mon, Sep 28
United Airlines Logo
5:30 am - 10:17 am
CMH
-
DSM
5h 47m
1 stop
United Airlines Logo
6:00 am - 2:18 pm
DSM
-
CMH
7h 18m
2 stops
$247United Airlines
Thu, Aug 6 - Wed, Aug 12
Southwest Logo
12:05 pm - 9:00 pm
CMH
-
DSM
9h 55m
2 stops
Southwest Logo
5:40 am - 12:30 pm
DSM
-
CMH
5h 50m
2 stops
$248Southwest
Tue, Sep 1 - Thu, Sep 10
Delta Logo
1:44 pm - 4:48 pm
CMH
-
DSM
4h 04m
1 stop
Delta Logo
10:59 am - 6:27 pm
DSM
-
CMH
6h 28m
1 stop
$250Delta
Fri, Sep 25 - Mon, Sep 28
United Airlines Logo
11:03 am - 2:27 pm
CMH
-
DSM
4h 24m
1 stop
United Airlines Logo
6:00 am - 3:38 pm
DSM
-
CMH
8h 38m
2 stops
$262United Airlines
Thu, Aug 6 - Wed, Aug 12
Delta Logo
10:54 am - 4:50 pm
CMH
-
DSM
6h 56m
1 stop
Delta Logo
6:55 am - 12:53 pm
DSM
-
CMH
4h 58m
1 stop
$271Delta
Mon, Aug 17 - Thu, Aug 20

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Delta flights from Columbus to Des Moines

Our best Delta deals on Columbus to Des Moines flight tickets
Delta
Oct 14
CMH6:25 amColumbus
4h 13m
1 stop
DSM9:38 amDes Moines
Oct 17
DSM4:00 pmDes Moines
6h 14m
1 stop
CMH11:14 pmColumbus
$221
Delta
Sep 25
CMH1:44 pmColumbus
4h 04m
1 stop
DSM4:48 pmDes Moines
Sep 28
DSM10:59 amDes Moines
6h 28m
1 stop
CMH6:27 pmColumbus
$250
Delta
Aug 17
CMH10:54 amColumbus
6h 56m
1 stop
DSM4:50 pmDes Moines
Aug 20
DSM6:55 amDes Moines
4h 58m
1 stop
CMH12:53 pmColumbus
$271

United Airlines flights from Columbus to Des Moines

Our best United Airlines deals on Columbus to Des Moines flight tickets
United Airlines
Sep 1
CMH3:15 pmColumbus
7h 08m
2 stops
DSM9:23 pmDes Moines
Sep 10
DSM6:29 amDes Moines
4h 11m
1 stop
CMH11:40 amColumbus
$226
United Airlines
Aug 12
CMH11:05 amColumbus
4h 11m
1 stop
DSM2:16 pmDes Moines
Aug 31
DSM3:20 pmDes Moines
7h 24m
2 stops
CMH11:44 pmColumbus
$241
United Airlines
Sep 25
CMH7:17 amColumbus
4h 14m
1 stop
DSM10:31 amDes Moines
Sep 28
DSM6:55 pmDes Moines
3h 59m
1 stop
CMH11:54 pmColumbus
$245

momondo Fare Finder

 
Customize your flight search to find flights from Columbus to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 12, 2026.
Use the filters below to find and compare flights from Columbus to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ColumbusDes Moines

CMH - DSM

CMHDSM

Columbus

Wed 10/14

6:25 am-9:38 am

1 stop4h 13m

Des Moines

Sat 10/17

4:00 pm-11:14 pm

1 stop6h 14m

$221

ColumbusDes Moines

CMH - DSM

CMHDSM

Columbus

Thu 8/6

5:31 am-9:56 am

1 stop5h 25m

Des Moines

Wed 8/12

6:55 am-1:52 pm

1 stop5h 57m

$222

ColumbusDes Moines

CMH - DSM

CMHDSM

Columbus

Tue 9/1

3:15 pm-9:23 pm

2 stops7h 08m

Des Moines

Thu 9/10

6:29 am-11:40 am

1 stop4h 11m

$226

ColumbusDes Moines

CMH - DSM

CMHDSM

Columbus

Wed 8/12

11:05 am-2:16 pm

1 stop4h 11m

Des Moines

Mon 8/31

3:20 pm-11:44 pm

2 stops7h 24m

$241
Quickest round-trip

ColumbusDes Moines

CMH - DSM

CMHDSM

Columbus

Fri 9/25

7:17 am-10:31 am

1 stop4h 14m

Des Moines

Mon 9/28

6:55 pm-11:54 pm

1 stop3h 59m

$245

ColumbusDes Moines

CMH - DSM

CMHDSM

Columbus

Thu 8/6

5:30 am-10:17 am

1 stop5h 47m

Des Moines

Wed 8/12

6:00 am-2:18 pm

2 stops7h 18m

$247

ColumbusDes Moines

CMH - DSM

CMHDSM

Columbus

Tue 9/1

12:05 pm-9:00 pm

2 stops9h 55m

Des Moines

Thu 9/10

5:40 am-12:30 pm

2 stops5h 50m

$248

ColumbusDes Moines

CMH - DSM

CMHDSM

Columbus

Fri 9/25

1:44 pm-4:48 pm

1 stop4h 04m

Des Moines

Mon 9/28

10:59 am-6:27 pm

1 stop6h 28m

$250

ColumbusDes Moines

CMH - DSM

CMHDSM

Columbus

Thu 8/6

11:03 am-2:27 pm

1 stop4h 24m

Des Moines

Wed 8/12

6:00 am-3:38 pm

2 stops8h 38m

$262

ColumbusDes Moines

CMH - DSM

CMHDSM

Columbus

Mon 8/17

10:54 am-4:50 pm

1 stop6h 56m

Des Moines

Thu 8/20

6:55 am-12:53 pm

1 stop4h 58m

$271

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Columbus to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in October, then September is your next best option. Flight prices from Columbus to Des Moines during September average around $236.

Cheap Columbus to Des Moines flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Columbus to Des Moines

Fastest flight time

3h 35m

Direct flights

None
The fastest flight from Columbus to Des Moines takes 3h 35m
There are no direct flights from Columbus to Des Moines. There are no popular flight routes from Columbus to Des Moines.
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Frequently asked questions about flying from Columbus to Des Moines

  • How far is Columbus to Des Moines by plane?

    A flight from Columbus to Des Moines will travel around 566.8 mi. 3h 35m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Columbus to Des Moines Airport?

    Prices for flights from Columbus to Des Moines Airport are updated daily.

  • How many operators does momondo search for flights from Columbus to Des Moines Airport?

  • How old do you have to be to fly from Columbus to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Columbus to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Columbus to Des Moines

Compare and see reviews for airlines that fly from Columbus to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $228Free CancellationRating
7.1
11,804 reviews
Search American Airlines flights
DeltaPriceFrom $236Free CancellationRating
7.8
8,458 reviews
Search Delta flights
United AirlinesPriceFrom $249Free CancellationRating
7.4
9,980 reviews
Search United Airlines flights
SouthwestPriceFrom $367Free CancellationRating
7.9
4,251 reviews
Search Southwest flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Clive
Altoona
Pella
Osceola
Urbandale
Johnston
Newton
Boone
Oskaloosa
Grinnell
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Columbus to Des Moines?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Columbus to Des Moines. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Columbus to Des Moines with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Des Moines from Columbus with this policy.

How can momondo help me find flights from Columbus to Des Moines?

momondo provides multiple filters to help you find the best flight to Des Moines from Columbus. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Columbus to Des Moines right now. Can momondo alert me if prices change?

Price alerts on flights to Des Moines from Columbus are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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