What is the cheapest airline that flies from Columbus to Des Moines?

American Airlines, Southwest, and United Airlines are the most popular carriers operating from Columbus to Des Moines

What airlines fly to Des Moines?

American Airlines, United Airlines and Delta are the top three most popular airlines that fly to Des Moines from Columbus according to our data. American Airlines is the first choice among our users, with 35% of people opting to fly with this airline when traveling to Des Moines. Keep in mind that there are 4 different airlines that fly to Des Moines on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Columbus to Des Moines Airport?

Prices for flights from Columbus to Des Moines Airport are updated daily.

How many operators does momondo search for flights from Columbus to Des Moines Airport?

As of October 2025, there are 4 operators available to choose from for flights from Columbus to Des Moines Airport.

How old do you have to be to fly from Columbus to Des Moines Airport?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Columbus to Des Moines Airport.

What documentation or ID do you need to fly to Des Moines Airport?

The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$129 Cheap Flights from Columbus to Des Moines in 2025/26

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Find the cheapest flights from Columbus to Des Moines

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

2:34 pm - 6:26 pmCMH-DSM

4h 52m1 stop

4:07 pm - 10:31 pmDSM-CMH

5h 24m1 stop

$257American Airlines

Find Deal

Tue, Dec 2 - Thu, Dec 4

9:00 am - 11:25 amCMH-DSM

3h 25m1 stop

6:15 am - 4:05 pmDSM-CMH

8h 50m2 stops

$262Southwest

Find Deal

Mon, Dec 8 - Tue, Dec 9

4:25 pm - 9:37 pmCMH-DSM

6h 12m1 stop

3:17 pm - 10:09 pmDSM-CMH

5h 52m1 stop

$287United Airlines

Find Deal

Tue, Dec 2 - Thu, Dec 4

9:00 am - 11:25 amCMH-DSM

3h 25m1 stop

6:15 am - 4:05 pmDSM-CMH

8h 50m2 stops

$306Southwest

Find Deal

Tue, Dec 2 - Thu, Dec 4

9:00 am - 11:25 amCMH-DSM

3h 25m1 stop

4:15 pm - 8:30 pmDSM-CMH

3h 15m1 stop

$312Southwest

Find Deal

Wed, Dec 3 - Fri, Dec 5

1:46 pm - 5:03 pmCMH-DSM

4h 17m1 stop

11:23 am - 5:31 pmDSM-CMH

5h 08m1 stop

$321Delta

Find Deal

Tue, Dec 2 - Thu, Dec 4

4:25 pm - 9:37 pmCMH-DSM

6h 12m1 stop

8:00 am - 7:03 pmDSM-CMH

10h 03m2 stops

$332United Airlines

Find Deal

Tue, Dec 2 - Thu, Dec 4

6:00 am - 10:21 pmCMH-DSM

17h 21m2 stops

6:35 am - 7:38 pmDSM-CMH

36h 03m3 stops

$382Multiple Airlines

Find Deal

Sun, Dec 7 - Mon, Dec 8

6:00 am - 11:24 pmCMH-DSM

18h 24m1 stop

8:19 pm - 7:02 pmDSM-CMH

21h 43m2 stops

$391Multiple Airlines

Find Deal

Tue, Nov 25 - Sun, Nov 30

6:25 am - 9:30 amCMH-DSM

4h 05m1 stop

5:25 pm - 12:01 amDSM-CMH

5h 36m1 stop

$413Delta

Find Deal

Thu, Mar 5 - Mon, Mar 9

Southwest flights from Columbus to Des Moines

Our best Southwest deals on Columbus to Des Moines flight tickets

Southwest

Dec 8

CMH9:00 amColumbus

3h 25m

1 stop

DSM11:25 amDes Moines

Dec 9

DSM6:15 amDes Moines

8h 50m

2 stops

CMH4:05 pmColumbus

$262

Find similar

Southwest

Dec 2

CMH9:00 amColumbus

3h 25m

1 stop

DSM11:25 amDes Moines

Dec 4

DSM6:15 amDes Moines

8h 50m

2 stops

CMH4:05 pmColumbus

$306

Find similar

Southwest

Dec 3

CMH9:00 amColumbus

3h 25m

1 stop

DSM11:25 amDes Moines

Dec 5

DSM4:15 pmDes Moines

3h 15m

1 stop

CMH8:30 pmColumbus

$312

Find similar

Delta flights from Columbus to Des Moines

Our best Delta deals on Columbus to Des Moines flight tickets

Delta

Dec 2

CMH1:46 pmColumbus

4h 17m

1 stop

DSM5:03 pmDes Moines

Dec 4

DSM11:23 amDes Moines

5h 08m

1 stop

CMH5:31 pmColumbus

$321

Find similar

Delta

Mar 5

CMH6:25 amColumbus

4h 05m

1 stop

DSM9:30 amDes Moines

Mar 9

DSM5:25 pmDes Moines

5h 36m

1 stop

CMH12:01 amColumbus

$413

Find similar

Delta

Nov 13

CMH7:00 amColumbus

4h 42m

1 stop

DSM10:42 amDes Moines

Nov 17

DSM5:35 amDes Moines

5h 03m

1 stop

CMH11:38 amColumbus

$447

Find similar

Fly from

Fly to

Route

Depart

Return

Price

ColumbusDes Moines

CMH - DSM

CMHDSM

Columbus

Tue 12/2

2:34 pm-6:26 pm

1 stop4h 52m

Des Moines

Thu 12/4

4:07 pm-10:31 pm

1 stop5h 24m

$257

ColumbusDes Moines

CMH - DSM

CMHDSM

Columbus

Mon 12/8

9:00 am-11:25 am

1 stop3h 25m

Des Moines

Tue 12/9

6:15 am-4:05 pm

2 stops8h 50m

$262

ColumbusDes Moines

CMH - DSM

CMHDSM

Columbus

Tue 12/2

4:25 pm-9:37 pm

1 stop6h 12m

Des Moines

Thu 12/4

3:17 pm-10:09 pm

1 stop5h 52m

$287

ColumbusDes Moines

CMH - DSM

CMHDSM

Columbus

Tue 12/2

9:00 am-11:25 am

1 stop3h 25m

Des Moines

Thu 12/4

6:15 am-4:05 pm

2 stops8h 50m

$306

ColumbusDes Moines

CMH - DSM

CMHDSM

Columbus

Wed 12/3

9:00 am-11:25 am

1 stop3h 25m

Des Moines

Fri 12/5

4:15 pm-8:30 pm

1 stop3h 15m

$312

ColumbusDes Moines

CMH - DSM

CMHDSM

Columbus

Tue 12/2

1:46 pm-5:03 pm

1 stop4h 17m

Des Moines

Thu 12/4

11:23 am-5:31 pm

1 stop5h 08m

$321

ColumbusDes Moines

CMH - DSM

CMHDSM

Columbus

Tue 12/2

4:25 pm-9:37 pm

1 stop6h 12m

Des Moines

Thu 12/4

8:00 am-7:03 pm

2 stops10h 03m

$332

ColumbusDes Moines

CMH - DSM

CMHDSM

Columbus

Sun 12/7

6:00 am-10:21 pm

2 stops17h 21m

Des Moines

Mon 12/8

6:35 am-7:38 pm

3 stops36h 03m

$382

ColumbusDes Moines

CMH - DSM

CMHDSM

Columbus

Tue 11/25

6:00 am-11:24 pm

1 stop18h 24m

Des Moines

Sun 11/30

8:19 pm-7:02 pm

2 stops21h 43m

$391

ColumbusDes Moines

CMH - DSM

CMHDSM

Columbus

Thu 3/5

6:25 am-9:30 am

1 stop4h 05m

Des Moines

Mon 3/9

5:25 pm-12:01 am

1 stop5h 36m

$413

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Columbus to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Columbus to Des Moines is on a Saturday. Travelers who choose to depart for Des Moines on a Saturday will often find tickets for as low as $340. Flights from Columbus to Des Moines on a Thursday will generally be more expensive and average around $509. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is at noon. momondo users have found flights departing from Columbus to Des Moines at noon for as low as $346. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the afternoon because they tend to be around $446. Of course, these prices can vary depending on the time of year and what airport you fly to.

Cheap Columbus to Des Moines flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Columbus to Des Moines

Direct flights	None

There are no direct flights from Columbus to Des Moines. There are no popular flight routes from Columbus to Des Moines.

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How far is Columbus to Des Moines by plane?
A flight from Columbus to Des Moines will travel around 566.8 mi. 3h 25m is a normal flight duration for this route.
When did momondo last update prices for flights from Columbus to Des Moines Airport?
Prices for flights from Columbus to Des Moines Airport are updated daily.
How many operators does momondo search for flights from Columbus to Des Moines Airport?
As of October 2025, there are 4 operators available to choose from for flights from Columbus to Des Moines Airport.
How old do you have to be to fly from Columbus to Des Moines Airport?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Columbus to Des Moines Airport.
What documentation or ID do you need to fly to Des Moines Airport?
The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Columbus to Des Moines

Compare and see reviews for airlines that fly from Columbus to Des Moines with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $216	Free Cancellation	Rating 7.9 7,998 reviews	Search Delta flights
American Airlines	PriceFrom $236	Free Cancellation	Rating 7.2 11,035 reviews	Search American Airlines flights
United Airlines	PriceFrom $243	Free Cancellation	Rating 7.4 8,998 reviews	Search United Airlines flights
Southwest	PriceFrom $306	Free Cancellation	Rating 8.0 4,243 reviews	Search Southwest flights

West Des Moines

Ames

Ankeny

Altoona

Urbandale

Clive

Pella

Newton

Johnston

Osceola

Boone

Norwalk

Grinnell

Oskaloosa

Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Columbus to Des Moines?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Columbus to Des Moines. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Columbus to Des Moines with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Des Moines from Columbus with this policy.

How can momondo help me find flights from Columbus to Des Moines?

momondo provides multiple filters to help you find the best flight to Des Moines from Columbus. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Columbus to Des Moines right now. Can momondo alert me if prices change?

Price alerts on flights to Des Moines from Columbus are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.