Cheap flights from Columbia to Chicago from $269

The month of January is, on average, the cheapest month to fly to Chicago from Columbia, with most prices found around $279. If you’re not able to fly to Chicago in January, then August is your next best option. Flight prices from Columbia to Chicago during August average around $332.

The cheapest day to depart on your flight to Chicago is on a Thursday when prices can be found for as low as $416. This is often the case because there is less demand to fly during this day of the week. When flying out on a Monday, the most expensive travel day of the week, you can expect to see flight prices from Columbia to Chicago for around $699.

Our most recent data shows that the best time of day to fly to Chicago is in the afternoon. Flights from Columbia to Chicago during this time can be as low as $460. In contrast, the most expensive time of day to depart to Chicago is at noon when prices are around $500.

Fly from Columbia Metropolitan to Chicago O'Hare Intl for the best Columbia Metropolitan - Chicago flight prices

You are more likely to see cheaper flights to Chicago from Columbia when booking weeks ahead of your departure date. In general, you can expect to find flights to Chicago for around $386 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Chicago from Columbia for as low as $272 on momondo.

There are 4 cabin classes available to choose from on Columbia to Chicago flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 44% on your flight if you consider stops on a Columbia to Chicago flight.

As of September 2026, prices for Columbia to Chicago flights are approximately 89% more expensive when compared to flights at the same time last year.

American Airlines, Delta, and United Airlines are the most popular carriers operating from Columbia Metropolitan to Chicago

American Airlines, United Airlines and Frontier are the top three most popular airlines that fly to Chicago from Columbia according to our data. American Airlines is the first choice among our users, with 53% of people opting to fly with this airline when traveling to Chicago. Keep in mind that there are 6 different airlines that fly to Chicago on a routine basis, so you have a few additional options to choose from.

8 flights are operational daily from Columbia to Chicago as of September 2026. The most popular departure time for this route is 5:00PM, with 59% of flights per day taking off at noon.

61 flights are operational weekly from Columbia to Chicago as of September 2026. The most popular departure day for this route is Fri, with 16% of flights per week taking off on this day.