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Cheap flights from Chicago to Missouri from $69

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago to Missouri departing on 6/16. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Chicago to Missouri

Cheap round-trip flights

Enter your travel dates to find the best prices.
Contour Logo
12:10 pm - 1:50 pm
ORD
-
CGI
1h 40mnonstop
Contour Logo
9:50 am - 11:35 am
CGI
-
ORD
1h 45mnonstop
$163Contour
Mon, Jun 8 - Fri, Jun 12
Contour Logo
3:55 pm - 5:35 pm
ORD
-
CGI
1h 40mnonstop
Contour Logo
1:30 pm - 3:15 pm
CGI
-
ORD
1h 45mnonstop
$164Contour
Sat, Jun 6 - Wed, Jun 10
United Airlines Logo
8:40 am - 10:13 am
ORD
-
COU
1h 33mnonstop
United Airlines Logo
10:49 am - 12:30 pm
COU
-
ORD
1h 41mnonstop
$239United Airlines
Thu, Jul 2 - Sat, Jul 4
American Airlines Logo
8:15 am - 10:04 am
ORD
-
SGF
1h 49mnonstop
American Airlines Logo
2:21 pm - 4:13 pm
SGF
-
ORD
1h 52mnonstop
$248American Airlines
Mon, Jun 22 - Mon, Jun 29
American Airlines Logo
5:45 pm - 10:46 pm
ORD
-
COU
5h 01m
1 stop
American Airlines Logo
6:32 pm - 8:23 pm
COU
-
ORD
1h 51mnonstop
$248American Airlines
Thu, Jul 2 - Sun, Jul 5
United Airlines Logo
8:40 am - 10:13 am
ORD
-
COU
1h 33mnonstop
United Airlines Logo
8:00 am - 9:40 am
COU
-
ORD
1h 40mnonstop
$254United Airlines
Fri, Jun 12 - Sun, Jun 14
Southwest Logo
3:15 pm - 8:20 pm
MDW
-
STL
5h 05m
1 stop
Southwest Logo
5:30 pm - 10:00 pm
STL
-
MDW
4h 30m
1 stop
$257Southwest
Wed, Jul 1 - Fri, Jul 3
Southwest Logo
4:40 pm - 9:00 pm
MDW
-
STL
4h 20m
1 stop
Southwest Logo
5:55 pm - 7:05 pm
STL
-
MDW
1h 10mnonstop
$258Southwest
Mon, Jun 15 - Wed, Jun 17
Frontier Logo
9:10 am - 6:18 pm
ORD
-
STL
9h 08m
1 stop
Frontier Logo
12:11 pm - 5:07 am
STL
-
ORD
16h 56m
1 stop
$259Frontier
Wed, Jul 1 - Thu, Jul 2
Frontier Logo
12:27 pm - 5:30 pm
MDW
-
STL
5h 03m
1 stop
Frontier Logo
5:06 pm - 10:11 pm
STL
-
MDW
5h 05m
1 stop
$263Frontier
Thu, Jul 2 - Sat, Jul 4

Southwest flights from Chicago to Missouri

Our best Southwest deals on Chicago to Missouri flight tickets
Southwest
Jul 16
MDW10:20 amChicago Midway
4h 30m
2 stops
STL2:50 pmLambert-St Louis
Jul 21
STL9:40 amLambert-St Louis
1h 05m
MDW10:45 amChicago Midway
$252
Southwest
Jul 1
MDW3:15 pmChicago Midway
5h 05m
1 stop
STL8:20 pmLambert-St Louis
Jul 3
STL5:30 pmLambert-St Louis
4h 30m
1 stop
MDW10:00 pmChicago Midway
$257
Southwest
Jun 16
MDW9:10 amChicago Midway
5h 40m
1 stop
STL2:50 pmLambert-St Louis
Jun 19
STL9:55 pmLambert-St Louis
1h 05m
MDW11:00 pmChicago Midway
$258

Frontier flights from Chicago to Missouri

Our best Frontier deals on Chicago to Missouri flight tickets
Frontier
Jul 1
ORD9:10 amChicago O'Hare Intl
9h 08m
1 stop
STL6:18 pmLambert-St Louis
Jul 2
STL12:11 pmLambert-St Louis
16h 56m
1 stop
ORD5:07 amChicago O'Hare Intl
$259
Frontier
Jul 2
MDW12:27 pmChicago Midway
5h 03m
1 stop
STL5:30 pmLambert-St Louis
Jul 4
STL5:06 pmLambert-St Louis
5h 05m
1 stop
MDW10:11 pmChicago Midway
$263
Frontier
Sep 13
ORD6:05 amChicago O'Hare Intl
11h 39m
1 stop
STL5:44 pmLambert-St Louis
Sep 17
STL10:35 amLambert-St Louis
9h 09m
1 stop
ORD7:44 pmChicago O'Hare Intl
$264

momondo Fare Finder

 
Customize your flight search to find flights from Chicago to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 26, 2026.
Use the filters below to find and compare flights from Chicago to Missouri that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ChicagoCape Girardeau

ORD - CGI

ORDCGI

Chicago O'Hare Intl

Mon 6/8

12:10 pm-1:50 pm

Nonstop1h 40m

Cape Girardeau

Fri 6/12

9:50 am-11:35 am

Nonstop1h 45m

$163

ChicagoCape Girardeau

ORD - CGI

ORDCGI

Chicago O'Hare Intl

Sat 6/6

3:55 pm-5:35 pm

Nonstop1h 40m

Cape Girardeau

Wed 6/10

1:30 pm-3:15 pm

Nonstop1h 45m

$164

ChicagoColumbia

ORD - COU

ORDCOU

Chicago O'Hare Intl

Thu 7/2

8:40 am-10:13 am

Nonstop1h 33m

Columbia Regional

Sat 7/4

10:49 am-12:30 pm

Nonstop1h 41m

$239

ChicagoSpringfield

ORD - SGF

ORDSGF

Chicago O'Hare Intl

Mon 6/22

8:15 am-10:04 am

Nonstop1h 49m

Springfield-Branson

Mon 6/29

2:21 pm-4:13 pm

Nonstop1h 52m

$248

ChicagoColumbia

ORD - COU

ORDCOU

Chicago O'Hare Intl

Thu 7/2

5:45 pm-10:46 pm

1 stop5h 01m

Columbia Regional

Sun 7/5

6:32 pm-8:23 pm

Nonstop1h 51m

$248
Quickest round-trip

ChicagoColumbia

ORD - COU

ORDCOU

Chicago O'Hare Intl

Fri 6/12

8:40 am-10:13 am

Nonstop1h 33m

Columbia Regional

Sun 6/14

8:00 am-9:40 am

Nonstop1h 40m

$254

ChicagoSt. Louis

MDW - STL

MDWSTL

Chicago Midway

Wed 7/1

3:15 pm-8:20 pm

1 stop5h 05m

Lambert-St Louis

Fri 7/3

5:30 pm-10:00 pm

1 stop4h 30m

$257

ChicagoSt. Louis

MDW - STL

MDWSTL

Chicago Midway

Mon 6/15

4:40 pm-9:00 pm

1 stop4h 20m

Lambert-St Louis

Wed 6/17

5:55 pm-7:05 pm

Nonstop1h 10m

$258

ChicagoSt. Louis

ORD - STL

ORDSTL

Chicago O'Hare Intl

Wed 7/1

9:10 am-6:18 pm

1 stop9h 08m

Lambert-St Louis

Thu 7/2

12:11 pm-5:07 am

1 stop16h 56m

$259

ChicagoSt. Louis

MDW - STL

MDWSTL

Chicago Midway

Thu 7/2

12:27 pm-5:30 pm

1 stop5h 03m

Lambert-St Louis

Sat 7/4

5:06 pm-10:11 pm

1 stop5h 05m

$263

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Missouri from

How to get the cheapest flight ticket from Chicago to Missouri

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Missouri?

In general, September is the cheapest month to fly from Chicago to Missouri. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $68. If you aren’t able to travel to Missouri during the month of September, then flying in October is also cheap. Prices for this month can be found on momondo for an average of $75.

What is the cheapest day to depart on your flight to Missouri?

The cheapest day to depart from Chicago to Missouri is on a Saturday when prices can be found for as low as $264. Flights from Chicago to Missouri on a Monday will generally be more expensive and average around $579. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Missouri?

According to our data, the cheapest time of day to fly to Missouri is at noon. momondo users have found flights departing from Chicago to Missouri at noon for as low as $336. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights to Missouri are more costly in the afternoon, with an average ticket price of $555. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest Chicago to Missouri flight route?

Fly from Chicago O'Hare Intl to Kirksville Cannon Memorial for the best Chicago - Missouri flight prices

How far in advance should I book a flight from Chicago to Missouri?

You are more likely to see cheaper flights to Missouri from Chicago when booking weeks ahead of your departure date. In general, you can expect to find flights to Missouri for around $379 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Missouri from Chicago for as low as $165 on momondo.

What cabin class options are available on Chicago to Missouri flights?

There are 4 cabin classes available to choose from on Chicago to Missouri flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Chicago to Missouri flights?

No. A direct flight is the cheapest option for a flight between Chicago to Missouri.

Cheap Chicago to Missouri flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago to Missouri

Best Price Found

$59

Fastest flight time

1h 10m

Direct flights

Every day

Airports in Missouri

55 airports
The best one-way flight to Missouri from Chicago in the past 72 hours is $59. The best round-trip flight deal from Chicago to Missouri found on momondo in the last 72 hours is $181.
The fastest flight from Chicago to Missouri takes 1h 10m
Direct flights go from Chicago to Missouri every day.
There are 55 airports in Missouri. From Chicago there are direct flights to Kansas City (MCI), Columbia Regional (COU), Lambert-St Louis (STL).
Search flight deals

Frequently asked questions about flying from Chicago to Missouri

  • When did momondo last update prices for flights from Chicago to Missouri?

    Prices for flights from Chicago to Missouri were last updated today.

  • How many operators does momondo search for flights from Chicago to Missouri?

  • How old do you have to be to fly from Chicago to Missouri?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Chicago to Missouri.

  • What documentation or ID do you need to fly to Missouri?

    The travel and health documents required for your trip to Missouri can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Missouri. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Chicago to Missouri?

Best airlines flying from Chicago to Missouri

Compare and see reviews for airlines that fly from Chicago to Missouri with momondo
Airline
Rating
Free Cancellation
Price
SouthwestPriceFrom $77Free CancellationRating
8.0
4,266 reviews
Search Southwest flights
ContourPriceFrom $92Free CancellationRating
7.7
41 reviews
Search Contour flights
American AirlinesPriceFrom $124Free CancellationRating
7.1
11,629 reviews
Search American Airlines flights
United AirlinesPriceFrom $155Free CancellationRating
7.4
9,748 reviews
Search United Airlines flights
Southern / MokulelePriceFrom $165Free CancellationRating
0.0
0 reviews
Search Southern / Mokulele flights

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Missouri?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Chicago to Missouri. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Chicago to Missouri with flexible booking policies on momondo?

Flights from Chicago to Missouri with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Chicago to Missouri?

momondo provides multiple filters to help you find the best flight to Missouri from Chicago. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Chicago to Missouri right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Chicago to Missouri now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Missouri and let you know when they change.

An easier way to manage your Missouri trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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