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Cheap flights from Chicago to Missouri from $78

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago to Missouri departing on 8/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Chicago to Missouri

Cheap round-trip flights

Enter your travel dates to find the best prices.
Contour Logo
12:10 pm - 1:50 pm
ORD
-
CGI
1h 40mnonstop
Contour Logo
9:50 am - 11:45 am
CGI
-
ORD
1h 55mnonstop
$164Contour
Thu, Jul 30 - Tue, Aug 4
Contour Logo
11:15 am - 12:50 pm
ORD
-
CGI
1h 35mnonstop
Contour Logo
9:50 am - 11:45 am
CGI
-
ORD
1h 55mnonstop
$165Contour
Fri, Aug 28 - Mon, Aug 31
United Airlines Logo
9:20 pm - 10:55 pm
ORD
-
COU
1h 35mnonstop
United Airlines Logo
3:12 pm - 5:00 pm
COU
-
ORD
1h 48mnonstop
$239United Airlines
Fri, Aug 28 - Sat, Aug 29
American Airlines Logo
7:49 pm - 9:19 pm
ORD
-
COU
1h 30mnonstop
American Airlines Logo
6:00 am - 7:41 am
COU
-
ORD
1h 41mnonstop
$240American Airlines
Fri, Aug 7 - Sun, Aug 9
American Airlines Logo
8:57 pm - 10:43 pm
ORD
-
SGF
1h 46mnonstop
American Airlines Logo
8:04 pm - 10:00 pm
SGF
-
ORD
1h 56mnonstop
$249American Airlines
Fri, Aug 14 - Sun, Aug 16
Southwest Logo
11:45 am - 7:30 pm
MDW
-
MCI
7h 45m
2 stops
Southwest Logo
8:05 am - 1:55 pm
MCI
-
MDW
5h 50m
1 stop
$263Southwest
Sat, Aug 15 - Sat, Aug 22
Frontier Logo
2:41 pm - 12:53 pm
ORD
-
MCI
22h 12m
1 stop
Frontier Logo
11:26 am - 12:50 pm
MCI
-
ORD
25h 24m
2 stops
$264Frontier
Fri, Aug 21 - Mon, Aug 24
Southwest Logo
5:30 pm - 10:55 pm
MDW
-
MCI
5h 25m
1 stop
Southwest Logo
4:15 pm - 10:20 pm
MCI
-
MDW
6h 05m
1 stop
$265Southwest
Thu, Sep 17 - Mon, Sep 21
Frontier Logo
6:30 am - 5:16 pm
ORD
-
MCI
10h 46m
1 stop
Frontier Logo
2:17 pm - 9:35 pm
MCI
-
ORD
7h 18m
1 stop
$265Frontier
Fri, Sep 18 - Tue, Sep 22
United Airlines Logo
7:15 am - 9:07 am
ORD
-
MCI
1h 52mnonstop
United Airlines Logo
6:39 pm - 8:33 pm
MCI
-
ORD
1h 54mnonstop
$269United Airlines
Wed, Oct 7 - Mon, Oct 12

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Southwest flights from Chicago to Missouri

Our best Southwest deals on Chicago to Missouri flight tickets
Southwest
Aug 15
MDW11:45 amChicago Midway
7h 45m
2 stops
MCI7:30 pmKansas City
Aug 22
MCI8:05 amKansas City
5h 50m
1 stop
MDW1:55 pmChicago Midway
$263
Southwest
Sep 17
MDW5:30 pmChicago Midway
5h 25m
1 stop
MCI10:55 pmKansas City
Sep 21
MCI4:15 pmKansas City
6h 05m
1 stop
MDW10:20 pmChicago Midway
$265
Southwest
Aug 12
MDW6:00 amChicago Midway
4h 35m
1 stop
MCI10:35 amKansas City
Aug 19
MCI9:50 amKansas City
6h 10m
2 stops
MDW4:00 pmChicago Midway
$270

United Airlines flights from Chicago to Missouri

Our best United Airlines deals on Chicago to Missouri flight tickets
United Airlines
Aug 28
ORD9:20 pmChicago O'Hare Intl
1h 35m
COU10:55 pmColumbia Regional
Aug 29
COU3:12 pmColumbia Regional
1h 48m
ORD5:00 pmChicago O'Hare Intl
$239
United Airlines
Oct 7
ORD7:15 amChicago O'Hare Intl
1h 52m
MCI9:07 amKansas City
Oct 12
MCI6:39 pmKansas City
1h 54m
ORD8:33 pmChicago O'Hare Intl
$269
United Airlines
Sep 4
ORD7:59 pmChicago O'Hare Intl
1h 45m
MCI9:44 pmKansas City
Sep 7
MCI5:08 pmKansas City
1h 54m
ORD7:02 pmChicago O'Hare Intl
$283

momondo Fare Finder

 
Customize your flight search to find flights from Chicago to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 18, 2026.
Use the filters below to find and compare flights from Chicago to Missouri that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ChicagoCape Girardeau

ORD - CGI

ORDCGI

Chicago O'Hare Intl

Thu 7/30

12:10 pm-1:50 pm

Nonstop1h 40m

Cape Girardeau

Tue 8/4

9:50 am-11:45 am

Nonstop1h 55m

$164

ChicagoCape Girardeau

ORD - CGI

ORDCGI

Chicago O'Hare Intl

Fri 8/28

11:15 am-12:50 pm

Nonstop1h 35m

Cape Girardeau

Mon 8/31

9:50 am-11:45 am

Nonstop1h 55m

$165

ChicagoColumbia

ORD - COU

ORDCOU

Chicago O'Hare Intl

Fri 8/28

9:20 pm-10:55 pm

Nonstop1h 35m

Columbia Regional

Sat 8/29

3:12 pm-5:00 pm

Nonstop1h 48m

$239
Quickest round-trip

ChicagoColumbia

ORD - COU

ORDCOU

Chicago O'Hare Intl

Fri 8/7

7:49 pm-9:19 pm

Nonstop1h 30m

Columbia Regional

Sun 8/9

6:00 am-7:41 am

Nonstop1h 41m

$240

ChicagoSpringfield

ORD - SGF

ORDSGF

Chicago O'Hare Intl

Fri 8/14

8:57 pm-10:43 pm

Nonstop1h 46m

Springfield-Branson

Sun 8/16

8:04 pm-10:00 pm

Nonstop1h 56m

$249

ChicagoKansas City

MDW - MCI

MDWMCI

Chicago Midway

Sat 8/15

11:45 am-7:30 pm

2 stops7h 45m

Kansas City

Sat 8/22

8:05 am-1:55 pm

1 stop5h 50m

$263

ChicagoKansas City

ORD - MCI

ORDMCI

Chicago O'Hare Intl

Fri 8/21

2:41 pm-12:53 pm

1 stop22h 12m

Kansas City

Mon 8/24

11:26 am-12:50 pm

2 stops25h 24m

$264

ChicagoKansas City

MDW - MCI

MDWMCI

Chicago Midway

Thu 9/17

5:30 pm-10:55 pm

1 stop5h 25m

Kansas City

Mon 9/21

4:15 pm-10:20 pm

1 stop6h 05m

$265

ChicagoKansas City

ORD - MCI

ORDMCI

Chicago O'Hare Intl

Fri 9/18

6:30 am-5:16 pm

1 stop10h 46m

Kansas City

Tue 9/22

2:17 pm-9:35 pm

1 stop7h 18m

$265

ChicagoKansas City

ORD - MCI

ORDMCI

Chicago O'Hare Intl

Wed 10/7

7:15 am-9:07 am

Nonstop1h 52m

Kansas City

Mon 10/12

6:39 pm-8:33 pm

Nonstop1h 54m

$269

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Missouri from

How to get the cheapest flight ticket from Chicago to Missouri

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Missouri?

In general, October is the cheapest month to fly from Chicago to Missouri. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $299. If you aren’t able to travel to Missouri during the month of October, then flying in November is also cheap. Prices for this month can be found on momondo for an average of $317.

What is the cheapest day to depart on your flight to Missouri?

The cheapest day to depart from Chicago to Missouri is on a Saturday when prices can be found for as low as $294. Flights from Chicago to Missouri on a Monday will generally be more expensive and average around $545. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Missouri?

According to our data, the cheapest time of day to fly to Missouri is at noon. momondo users have found flights departing from Chicago to Missouri at noon for as low as $336. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights to Missouri are more costly in the afternoon, with an average ticket price of $517. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest Chicago to Missouri flight route?

Fly from Chicago O'Hare Intl to Kirksville Cannon Memorial for the best Chicago - Missouri flight prices

How far in advance should I book a flight from Chicago to Missouri?

You are more likely to see cheaper flights to Missouri from Chicago when booking weeks ahead of your departure date. In general, you can expect to find flights to Missouri for around $414 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Missouri from Chicago for as low as $171 on momondo.

What cabin class options are available on Chicago to Missouri flights?

There are 4 cabin classes available to choose from on Chicago to Missouri flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Chicago to Missouri flights?

No. A direct flight is the cheapest option for a flight between Chicago to Missouri.

Cheap Chicago to Missouri flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago to Missouri

Best Price Found

$66

Fastest flight time

1h 10m

Direct flights

Every day

Airports in Missouri

55 airports
The best one-way flight to Missouri from Chicago in the past 72 hours is $66. The best round-trip flight deal from Chicago to Missouri found on momondo in the last 72 hours is $138.
The fastest flight from Chicago to Missouri takes 1h 10m
Direct flights go from Chicago to Missouri every day.
There are 55 airports in Missouri. From Chicago there are direct flights to Kansas City (MCI), Columbia Regional (COU), Lambert-St Louis (STL).
Search flight deals

Frequently asked questions about flying from Chicago to Missouri

  • When did momondo last update prices for flights from Chicago to Missouri?

    Prices for flights from Chicago to Missouri were last updated today.

  • How many operators does momondo search for flights from Chicago to Missouri?

  • How old do you have to be to fly from Chicago to Missouri?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Chicago to Missouri.

  • What documentation or ID do you need to fly to Missouri?

    The travel and health documents required for your trip to Missouri can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Missouri. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Chicago to Missouri?

Best airlines flying from Chicago to Missouri

Compare and see reviews for airlines that fly from Chicago to Missouri with momondo
Airline
Rating
Free Cancellation
Price
SouthwestPriceFrom $77Free CancellationRating
8.0
4,242 reviews
Search Southwest flights
ContourPriceFrom $92Free CancellationRating
7.7
42 reviews
Search Contour flights
American AirlinesPriceFrom $151Free CancellationRating
7.1
11,829 reviews
Search American Airlines flights
United AirlinesPriceFrom $157Free CancellationRating
7.4
10,006 reviews
Search United Airlines flights
Southern / MokulelePriceFrom $165Free CancellationRating
0.0
0 reviews
Search Southern / Mokulele flights

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Missouri?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Chicago to Missouri. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Chicago to Missouri with flexible booking policies on momondo?

Flights from Chicago to Missouri with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Chicago to Missouri?

momondo provides multiple filters to help you find the best flight to Missouri from Chicago. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Chicago to Missouri right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Chicago to Missouri now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Missouri and let you know when they change.

An easier way to manage your Missouri trip

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Find better results for your trip to Missouri

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