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Cheap flights from Chicago to Missouri from $54

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago to Missouri departing on 12/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Contour Logo
11:50 am - 1:25 pm
ORD
-
CGI
1h 35mnonstop
Contour Logo
9:30 am - 11:10 am
CGI
-
ORD
1h 40mnonstop
$103Contour
Wed, Dec 31 - Sun, Jan 4
Contour Logo
11:50 am - 1:25 pm
ORD
-
CGI
1h 35mnonstop
Contour Logo
9:30 am - 11:10 am
CGI
-
ORD
1h 40mnonstop
$106Contour
Tue, Dec 30 - Sat, Jan 3
Multiple Airlines Logo
5:50 am - 2:48 pm
ORD
-
STL
8h 58m1 stop
Multiple Airlines Logo
5:11 pm - 1:13 pm
STL
-
ORD
20h 02m1 stop
$139Multiple Airlines
Thu, Jan 8 - Mon, Jan 12
Multiple Airlines Logo
1:20 pm - 6:51 am
ORD
-
STL
17h 31m1 stop
Multiple Airlines Logo
5:42 pm - 5:52 pm
STL
-
ORD
24h 10m1 stop
$141Multiple Airlines
Tue, Jan 13 - Tue, Jan 20
American Airlines Logo
8:50 am - 10:20 am
ORD
-
STL
1h 30mnonstop
American Airlines Logo
11:05 am - 12:34 pm
STL
-
ORD
1h 29mnonstop
$153American Airlines
Tue, Jan 13 - Tue, Jan 20
Southwest Logo
9:55 am - 11:15 am
MDW
-
STL
1h 20mnonstop
Southwest Logo
5:55 pm - 7:05 pm
STL
-
MDW
1h 10mnonstop
$171Southwest
Thu, Jan 8 - Mon, Jan 12
Southwest Logo
8:10 am - 12:45 pm
MDW
-
STL
4h 35m1 stop
Southwest Logo
1:10 pm - 2:15 pm
STL
-
MDW
1h 05mnonstop
$172Southwest
Tue, Jan 20 - Thu, Jan 22
American Airlines Logo
1:17 pm - 2:48 pm
ORD
-
COU
1h 31mnonstop
American Airlines Logo
11:56 am - 1:29 pm
COU
-
ORD
1h 33mnonstop
$179American Airlines
Fri, Jan 16 - Sun, Jan 18
United Airlines Logo
12:45 pm - 2:38 pm
ORD
-
SGF
1h 53mnonstop
United Airlines Logo
3:14 pm - 5:05 pm
SGF
-
ORD
1h 51mnonstop
$189United Airlines
Wed, Jan 14 - Wed, Jan 21
United Airlines Logo
12:45 pm - 2:38 pm
ORD
-
SGF
1h 53mnonstop
United Airlines Logo
7:45 am - 9:47 am
SGF
-
ORD
2h 02mnonstop
$190United Airlines
Thu, Jan 8 - Sun, Jan 11

Spirit Airlines flights from Chicago to Missouri

Our best Spirit Airlines deals on Chicago to Missouri flight tickets
Spirit Airlines
Jan 14
ORD6:05 amChicago O'Hare Intl
10h 04m
1 stop
MCI4:09 pmKansas City
Jan 21
MCI5:04 pmKansas City
25h 12m
3 stops
ORD6:16 pmChicago O'Hare Intl
$237
Find similar
Spirit Airlines
Jan 22
ORD8:43 pmChicago O'Hare Intl
19h 26m
2 stops
MCI4:09 pmKansas City
Jan 26
MCI11:26 amKansas City
30h 26m
3 stops
ORD5:52 pmChicago O'Hare Intl
$243
Find similar
Spirit Airlines
Dec 31
ORD7:20 amChicago O'Hare Intl
15h 39m
1 stop
MCI10:59 pmKansas City
Jan 6
MCI6:15 pmKansas City
21h 45m
2 stops
ORD4:00 pmChicago O'Hare Intl
$319
Find similar

Southwest flights from Chicago to Missouri

Our best Southwest deals on Chicago to Missouri flight tickets
Southwest
Jan 8
MDW7:45 pmChicago Midway
1h 15m
STL9:00 pmLambert-St Louis
Jan 12
STL5:55 pmLambert-St Louis
1h 10m
MDW7:05 pmChicago Midway
$171
Find similar
Southwest
Jan 8
MDW7:05 amChicago Midway
6h 30m
1 stop
STL1:35 pmLambert-St Louis
Jan 12
STL5:55 pmLambert-St Louis
1h 10m
MDW7:05 pmChicago Midway
$181
Find similar
Southwest
Jan 29
MDW6:10 amChicago Midway
1h 25m
STL7:35 amLambert-St Louis
Jan 31
STL1:40 pmLambert-St Louis
6h 05m
2 stops
MDW7:45 pmChicago Midway
$186
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Chicago to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Chicago to Missouri that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoCape Girardeau

ORD - CGI

ORDCGI

Chicago O'Hare Intl

Wed 12/31

11:50 am-1:25 pm

Nonstop1h 35m

Cape Girardeau

Sun 1/4

9:30 am-11:10 am

Nonstop1h 40m

$103

ChicagoCape Girardeau

ORD - CGI

ORDCGI

Chicago O'Hare Intl

Tue 12/30

11:50 am-1:25 pm

Nonstop1h 35m

Cape Girardeau

Sat 1/3

9:30 am-11:10 am

Nonstop1h 40m

$106

ChicagoSt. Louis

ORD - STL

ORDSTL

Chicago O'Hare Intl

Thu 1/8

5:50 am-2:48 pm

1 stop8h 58m

Lambert-St Louis

Mon 1/12

5:11 pm-1:13 pm

1 stop20h 02m

$139

ChicagoSt. Louis

ORD - STL

ORDSTL

Chicago O'Hare Intl

Tue 1/13

1:20 pm-6:51 am

1 stop17h 31m

Lambert-St Louis

Tue 1/20

5:42 pm-5:52 pm

1 stop24h 10m

$141

ChicagoSt. Louis

ORD - STL

ORDSTL

Chicago O'Hare Intl

Tue 1/13

8:50 am-10:20 am

Nonstop1h 30m

Lambert-St Louis

Tue 1/20

11:05 am-12:34 pm

Nonstop1h 29m

$153

ChicagoSt. Louis

MDW - STL

MDWSTL

Chicago Midway

Thu 1/8

9:55 am-11:15 am

Nonstop1h 20m

Lambert-St Louis

Mon 1/12

5:55 pm-7:05 pm

Nonstop1h 10m

$171

ChicagoSt. Louis

MDW - STL

MDWSTL

Chicago Midway

Tue 1/20

8:10 am-12:45 pm

1 stop4h 35m

Lambert-St Louis

Thu 1/22

1:10 pm-2:15 pm

Nonstop1h 05m

$172

ChicagoColumbia

ORD - COU

ORDCOU

Chicago O'Hare Intl

Fri 1/16

1:17 pm-2:48 pm

Nonstop1h 31m

Columbia Regional

Sun 1/18

11:56 am-1:29 pm

Nonstop1h 33m

$179

ChicagoSpringfield

ORD - SGF

ORDSGF

Chicago O'Hare Intl

Wed 1/14

12:45 pm-2:38 pm

Nonstop1h 53m

Springfield-Branson

Wed 1/21

3:14 pm-5:05 pm

Nonstop1h 51m

$189

ChicagoSpringfield

ORD - SGF

ORDSGF

Chicago O'Hare Intl

Thu 1/8

12:45 pm-2:38 pm

Nonstop1h 53m

Springfield-Branson

Sun 1/11

7:45 am-9:47 am

Nonstop2h 02m

$190

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Missouri from

How to get the cheapest flight ticket from Chicago to Missouri

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Missouri?

In general, November is the cheapest month to fly from Chicago to Missouri. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $240. If you aren’t able to travel to Missouri during the month of November, then flying in February is also cheap. Prices for this month can be found on momondo for an average of $257.

What is the cheapest day to depart on your flight to Missouri?

The cheapest day to depart from Chicago to Missouri is on a Wednesday when prices can be found for as low as $277. Flights from Chicago to Missouri on a Monday will generally be more expensive and average around $451. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Missouri?

According to our data, the cheapest time of day to fly to Missouri is in the evening. momondo users have found flights departing from Chicago to Missouri in the evening for as low as $265. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights to Missouri are more costly in the afternoon, with an average ticket price of $357. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest Chicago to Missouri flight route?

Fly from Chicago O'Hare Intl to Cape Girardeau for the best Chicago - Missouri flight prices

How far in advance should I book a flight to Missouri?

You are more likely to see cheaper flights to Missouri from Chicago when booking weeks ahead of your departure date. In general, you can expect to find flights to Missouri for around $287 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Missouri from Chicago for as low as $167 on momondo.

What cabin class options are available on Chicago to Missouri flights?

There are 4 cabin classes available to choose from on Chicago to Missouri flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Chicago to Missouri flights?

No. A direct flight is the cheapest option for a flight between Chicago to Missouri.

Cheap Chicago to Missouri flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago to Missouri

Best Price Found

$49

Fastest flight time

1h 10m

Direct flights

Every day

Airports in Missouri

55 airports
The best one-way flight to Missouri from Chicago in the past 72 hours is $49. The best round-trip flight deal from Chicago to Missouri found on momondo in the last 72 hours is $178.
The fastest flight from Chicago to Missouri takes 1h 10m
Direct flights go from Chicago to Missouri every day.
There are 55 airports in Missouri. From Chicago there are direct flights to Kansas City (MCI), Columbia Regional (COU), Lambert-St Louis (STL).
Search flight deals

  • When did momondo last update prices for flights from Chicago to Missouri?

    Prices for flights from Chicago to Missouri were last updated today.

  • How many operators does momondo search for flights from Chicago to Missouri?

  • How old do you have to be to fly from Chicago to Missouri?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Chicago to Missouri.

  • What documentation or ID do you need to fly to Missouri?

    The travel and health documents required for your trip to Missouri can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Missouri. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Chicago to Missouri?

Best airlines flying from Chicago to Missouri

Compare and see reviews for airlines that fly from Chicago to Missouri with momondo
Airline
Rating
Free Cancellation
Price
SouthwestPriceFrom $77Free CancellationRating
7.9
4,250 reviews
Search Southwest flights
ContourPriceFrom $105Free CancellationRating
7.6
43 reviews
Search Contour flights
American AirlinesPriceFrom $115Free CancellationRating
7.2
11,055 reviews
Search American Airlines flights
United AirlinesPriceFrom $144Free CancellationRating
7.4
9,092 reviews
Search United Airlines flights
Southern / MokulelePriceFrom $145Free CancellationRating
0.0
0 reviews
Search Southern / Mokulele flights

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Missouri?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Chicago to Missouri. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Chicago to Missouri with flexible booking policies on momondo?

Flights from Chicago to Missouri with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Chicago to Missouri?

momondo provides multiple filters to help you find the best flight to Missouri from Chicago. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Chicago to Missouri right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Chicago to Missouri now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Missouri and let you know when they change.

An easier way to manage your Missouri trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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Find better results for your trip to Missouri

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