Latest deals
Insights
FAQs
Reviews
Price Alerts

Cheap flights from Chicago to Missouri from $43

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago to Missouri departing on 3/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Chicago to Missouri

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:59 am - 8:24 am
ORD
-
STL
1h 25mnonstop
American Airlines Logo
7:05 am - 8:36 am
STL
-
ORD
1h 31mnonstop
$91American Airlines
Thu, Apr 9 - Sat, Apr 11
Southwest Logo
8:15 am - 9:35 am
MDW
-
STL
1h 20mnonstop
Southwest Logo
8:50 pm - 9:55 pm
STL
-
MDW
1h 05mnonstop
$97Southwest
Wed, Mar 11 - Wed, Mar 18
American Airlines Logo
10:30 pm - 11:46 pm
ORD
-
STL
1h 16mnonstop
American Airlines Logo
7:05 am - 8:36 am
STL
-
ORD
1h 31mnonstop
$97American Airlines
Sat, Apr 25 - Sun, Apr 26
Southwest Logo
3:20 pm - 8:00 pm
MDW
-
STL
4h 40m
1 stop
Southwest Logo
8:50 pm - 9:55 pm
STL
-
MDW
1h 05mnonstop
$107Southwest
Wed, Mar 11 - Wed, Mar 18
Contour Logo
11:50 am - 1:30 pm
ORD
-
CGI
1h 40mnonstop
Contour Logo
9:25 am - 11:10 am
CGI
-
ORD
1h 45mnonstop
$126Contour
Fri, Mar 6 - Sun, Mar 8
United Airlines Logo
9:33 pm - 10:59 pm
ORD
-
STL
1h 26mnonstop
United Airlines Logo
7:00 pm - 8:35 pm
STL
-
ORD
1h 35mnonstop
$128United Airlines
Sat, Mar 7 - Mon, Mar 9
Contour Logo
12:10 pm - 1:50 pm
ORD
-
CGI
1h 40mnonstop
Contour Logo
9:45 am - 11:30 am
CGI
-
ORD
1h 45mnonstop
$128Contour
Mon, Mar 30 - Thu, Apr 2
United Airlines Logo
9:30 pm - 10:56 pm
ORD
-
STL
1h 26mnonstop
United Airlines Logo
6:30 am - 7:59 am
STL
-
ORD
1h 29mnonstop
$134United Airlines
Wed, Apr 1 - Sat, Apr 4
Frontier Logo
2:13 pm - 9:05 am
ORD
-
MCI
18h 52m
1 stop
Frontier Logo
10:14 am - 10:39 pm
MCI
-
ORD
12h 25m
1 stop
$219Frontier
Fri, Feb 20 - Sun, Feb 22
Frontier Logo
5:05 am - 4:23 pm
ORD
-
MCI
11h 18m
1 stop
Frontier Logo
3:40 pm - 11:09 pm
MCI
-
ORD
7h 29m
1 stop
$224Frontier
Fri, Mar 6 - Sat, Mar 7

United Airlines flights from Chicago to Missouri

Our best United Airlines deals on Chicago to Missouri flight tickets
United Airlines
Mar 7
ORD9:33 pmChicago O'Hare Intl
1h 26m
STL10:59 pmLambert-St Louis
Mar 9
STL7:00 pmLambert-St Louis
1h 35m
ORD8:35 pmChicago O'Hare Intl
$128
United Airlines
Apr 1
ORD9:30 pmChicago O'Hare Intl
1h 26m
STL10:56 pmLambert-St Louis
Apr 4
STL6:30 amLambert-St Louis
1h 29m
ORD7:59 amChicago O'Hare Intl
$134
United Airlines
Mar 14
ORD4:35 pmChicago O'Hare Intl
1h 25m
STL6:00 pmLambert-St Louis
Mar 21
STL10:00 amLambert-St Louis
1h 33m
ORD11:33 amChicago O'Hare Intl
$145

Delta flights from Chicago to Missouri

Our best Delta deals on Chicago to Missouri flight tickets
Delta
Mar 10
MDW1:10 pmChicago Midway
3h 22m
1 stop
STL4:32 pmLambert-St Louis
Mar 11
STL12:28 pmLambert-St Louis
6h 12m
1 stop
MDW6:40 pmChicago Midway
$157
Delta
Apr 14
ORD8:52 amChicago O'Hare Intl
7h 58m
2 stops
STL4:50 pmLambert-St Louis
Apr 21
STL12:23 pmLambert-St Louis
5h 50m
1 stop
ORD6:13 pmChicago O'Hare Intl
$162
Delta
Mar 7
MDW6:00 amChicago Midway
5h 02m
1 stop
STL11:02 amLambert-St Louis
Mar 11
STL6:32 amLambert-St Louis
5h 57m
1 stop
MDW12:29 pmChicago Midway
$174

momondo Fare Finder

 
Customize your flight search to find flights from Chicago to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 15, 2026.
Use the filters below to find and compare flights from Chicago to Missouri that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoSt. Louis

ORD - STL

ORDSTL

Chicago O'Hare Intl

Thu 4/9

6:59 am-8:24 am

Nonstop1h 25m

Lambert-St Louis

Sat 4/11

7:05 am-8:36 am

Nonstop1h 31m

$91

ChicagoSt. Louis

MDW - STL

MDWSTL

Chicago Midway

Wed 3/11

8:15 am-9:35 am

Nonstop1h 20m

Lambert-St Louis

Wed 3/18

8:50 pm-9:55 pm

Nonstop1h 05m

$97

ChicagoSt. Louis

ORD - STL

ORDSTL

Chicago O'Hare Intl

Sat 4/25

10:30 pm-11:46 pm

Nonstop1h 16m

Lambert-St Louis

Sun 4/26

7:05 am-8:36 am

Nonstop1h 31m

$97

ChicagoSt. Louis

MDW - STL

MDWSTL

Chicago Midway

Wed 3/11

3:20 pm-8:00 pm

1 stop4h 40m

Lambert-St Louis

Wed 3/18

8:50 pm-9:55 pm

Nonstop1h 05m

$107

ChicagoCape Girardeau

ORD - CGI

ORDCGI

Chicago O'Hare Intl

Fri 3/6

11:50 am-1:30 pm

Nonstop1h 40m

Cape Girardeau

Sun 3/8

9:25 am-11:10 am

Nonstop1h 45m

$126

ChicagoSt. Louis

ORD - STL

ORDSTL

Chicago O'Hare Intl

Sat 3/7

9:33 pm-10:59 pm

Nonstop1h 26m

Lambert-St Louis

Mon 3/9

7:00 pm-8:35 pm

Nonstop1h 35m

$128

ChicagoCape Girardeau

ORD - CGI

ORDCGI

Chicago O'Hare Intl

Mon 3/30

12:10 pm-1:50 pm

Nonstop1h 40m

Cape Girardeau

Thu 4/2

9:45 am-11:30 am

Nonstop1h 45m

$128

ChicagoSt. Louis

ORD - STL

ORDSTL

Chicago O'Hare Intl

Wed 4/1

9:30 pm-10:56 pm

Nonstop1h 26m

Lambert-St Louis

Sat 4/4

6:30 am-7:59 am

Nonstop1h 29m

$134

ChicagoKansas City

ORD - MCI

ORDMCI

Chicago O'Hare Intl

Fri 2/20

2:13 pm-9:05 am

1 stop18h 52m

Kansas City

Sun 2/22

10:14 am-10:39 pm

1 stop12h 25m

$219

ChicagoKansas City

ORD - MCI

ORDMCI

Chicago O'Hare Intl

Fri 3/6

5:05 am-4:23 pm

1 stop11h 18m

Kansas City

Sat 3/7

3:40 pm-11:09 pm

1 stop7h 29m

$224

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Missouri from

How to get the cheapest flight ticket from Chicago to Missouri

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Missouri?

In general, December is the cheapest month to fly from Chicago to Missouri. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $217. If you aren’t able to travel to Missouri during the month of December, then flying in November is also cheap. Prices for this month can be found on momondo for an average of $240.

What is the cheapest day to depart on your flight to Missouri?

The cheapest day to depart from Chicago to Missouri is on a Wednesday when prices can be found for as low as $287. Flights from Chicago to Missouri on a Tuesday will generally be more expensive and average around $491. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Missouri?

According to our data, the cheapest time of day to fly to Missouri is at noon. momondo users have found flights departing from Chicago to Missouri at noon for as low as $317. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights to Missouri are more costly in the afternoon, with an average ticket price of $477. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest Chicago to Missouri flight route?

Fly from Chicago O'Hare Intl to Fort Leonard Wood Waynesville Regional for the best Chicago - Missouri flight prices

How far in advance should I book a flight to Missouri?

You are more likely to see cheaper flights to Missouri from Chicago when booking weeks ahead of your departure date. In general, you can expect to find flights to Missouri for around $308 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Missouri from Chicago for as low as $165 on momondo.

What cabin class options are available on Chicago to Missouri flights?

There are 4 cabin classes available to choose from on Chicago to Missouri flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Chicago to Missouri flights?

No. A direct flight is the cheapest option for a flight between Chicago to Missouri.

Cheap Chicago to Missouri flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago to Missouri

Best Price Found

$86

Fastest flight time

1h 10m

Direct flights

Every day

Airports in Missouri

55 airports
The best one-way flight to Missouri from Chicago in the past 72 hours is $86. The best round-trip flight deal from Chicago to Missouri found on momondo in the last 72 hours is $118.
The fastest flight from Chicago to Missouri takes 1h 10m
Direct flights go from Chicago to Missouri every day.
There are 55 airports in Missouri. From Chicago there are direct flights to Lambert-St Louis (STL).
Search flight deals

  • When did momondo last update prices for flights from Chicago to Missouri?

    Prices for flights from Chicago to Missouri were last updated today.

  • How many operators does momondo search for flights from Chicago to Missouri?

  • How old do you have to be to fly from Chicago to Missouri?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Chicago to Missouri.

  • What documentation or ID do you need to fly to Missouri?

    The travel and health documents required for your trip to Missouri can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Missouri. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Chicago to Missouri?

Best airlines flying from Chicago to Missouri

Compare and see reviews for airlines that fly from Chicago to Missouri with momondo
Airline
Rating
Free Cancellation
Price
SouthwestPriceFrom $77Free CancellationRating
8.0
4,285 reviews
Search Southwest flights
ContourPriceFrom $108Free CancellationRating
7.6
42 reviews
Search Contour flights
American AirlinesPriceFrom $121Free CancellationRating
7.2
11,294 reviews
Search American Airlines flights
United AirlinesPriceFrom $144Free CancellationRating
7.4
9,298 reviews
Search United Airlines flights
Southern / MokulelePriceFrom $156Free CancellationRating
0.0
0 reviews
Search Southern / Mokulele flights

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Missouri?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Chicago to Missouri. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Chicago to Missouri with flexible booking policies on momondo?

Flights from Chicago to Missouri with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Chicago to Missouri?

momondo provides multiple filters to help you find the best flight to Missouri from Chicago. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Chicago to Missouri right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Chicago to Missouri now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Missouri and let you know when they change.

An easier way to manage your Missouri trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Tue 3/17
Tue 3/24
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Missouri

Popular cities in Missouri

Popular flights according to clicks in the last 7 days on momondo
Flights to New Yorkfrom $52
Flights to Los Angelesfrom $52
Flights to Miamifrom $49
Flights to Chicagofrom $53
Flights to Orlandofrom $49
Flights to San Franciscofrom $56
Flights to Las Vegasfrom $50
Flights to Washington, D.C.from $25
Flights to Bostonfrom $69
Flights to Atlantafrom $49
Flights to Dallasfrom $49
Flights to Seattlefrom $51