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Cheap flights from Chicago to Knoxville from $86

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago to Knoxville departing on 1/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Chicago to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
10:48 am - 10:28 pm
ORD
-
TYS
10h 40m1 stop
Multiple Airlines Logo
1:39 pm - 9:12 pm
TYS
-
ORD
8h 33m1 stop
$170Multiple Airlines
Mon, Jan 12 - Sun, Jan 18
Multiple Airlines Logo
8:27 pm - 10:10 am
ORD
-
TYS
12h 43m1 stop
Multiple Airlines Logo
1:39 pm - 9:12 pm
TYS
-
ORD
8h 33m1 stop
$178Multiple Airlines
Sun, Jan 11 - Sun, Jan 18
Multiple Airlines Logo
8:08 pm - 3:03 pm
ORD
-
TYS
17h 55m1 stop
Multiple Airlines Logo
1:39 pm - 9:12 pm
TYS
-
ORD
8h 33m1 stop
$179Multiple Airlines
Tue, Jan 13 - Sun, Jan 18
Multiple Airlines Logo
10:48 am - 10:28 pm
ORD
-
TYS
10h 40m1 stop
Multiple Airlines Logo
1:39 pm - 9:12 pm
TYS
-
ORD
8h 33m1 stop
$182Multiple Airlines
Mon, Jan 12 - Thu, Jan 15
Multiple Airlines Logo
8:27 pm - 1:10 pm
ORD
-
TYS
15h 43m1 stop
Multiple Airlines Logo
1:39 pm - 9:12 pm
TYS
-
ORD
8h 33m1 stop
$186Multiple Airlines
Sat, Jan 10 - Sun, Jan 18
United Airlines Logo
6:00 pm - 8:37 pm
ORD
-
TYS
1h 37mnonstop
United Airlines Logo
10:53 am - 12:00 pm
TYS
-
ORD
2h 07mnonstop
$189United Airlines
Tue, Feb 17 - Tue, Feb 24
Multiple Airlines Logo
8:27 pm - 10:10 am
ORD
-
TYS
12h 43m1 stop
Multiple Airlines Logo
1:39 pm - 9:12 pm
TYS
-
ORD
8h 33m1 stop
$190Multiple Airlines
Sun, Jan 11 - Thu, Jan 15
Delta Logo
1:26 pm - 8:47 pm
MDW
-
TYS
6h 21m1 stop
Delta Logo
5:40 am - 9:53 am
TYS
-
MDW
5h 13m1 stop
$209Delta
Thu, Jan 22 - Sun, Jan 25
Delta Logo
5:31 pm - 11:45 pm
MDW
-
TYS
5h 14m1 stop
Delta Logo
7:30 am - 12:48 pm
TYS
-
MDW
6h 18m1 stop
$224Delta
Mon, Jan 5 - Sun, Jan 11
Southwest Logo
5:00 pm - 10:10 pm
MDW
-
TYS
4h 10m1 stop
Southwest Logo
3:45 pm - 10:00 pm
TYS
-
MDW
7h 15m1 stop
$317Southwest
Thu, Mar 5 - Mon, Mar 9

United Airlines flights from Chicago to Knoxville

Our best United Airlines deals on Chicago to Knoxville flight tickets
United Airlines
Mar 5
ORD6:06 pmChicago O'Hare Intl
1h 41m
TYS8:47 pmKnoxville McGhee Tyson
Mar 9
TYS7:00 amKnoxville McGhee Tyson
2h 00m
ORD8:00 amChicago O'Hare Intl
$189
Find similar
United Airlines
Jan 5
ORD2:07 pmChicago O'Hare Intl
1h 53m
TYS5:00 pmKnoxville McGhee Tyson
Jan 10
TYS11:07 amKnoxville McGhee Tyson
1h 58m
ORD12:05 pmChicago O'Hare Intl
$219
Find similar
United Airlines
Jan 1
ORD7:48 pmChicago O'Hare Intl
1h 51m
TYS10:39 pmKnoxville McGhee Tyson
Jan 8
TYS11:07 amKnoxville McGhee Tyson
1h 58m
ORD12:05 pmChicago O'Hare Intl
$229
Find similar

American Airlines flights from Chicago to Knoxville

Our best American Airlines deals on Chicago to Knoxville flight tickets
American Airlines
Jan 5
ORD11:41 amChicago O'Hare Intl
1h 50m
TYS2:31 pmKnoxville McGhee Tyson
Jan 11
TYS5:15 pmKnoxville McGhee Tyson
2h 11m
ORD6:26 pmChicago O'Hare Intl
$204
Find similar
American Airlines
Jan 1
ORD7:11 amChicago O'Hare Intl
6h 10m
1 stop
TYS2:21 pmKnoxville McGhee Tyson
Jan 8
TYS7:54 amKnoxville McGhee Tyson
2h 08m
ORD9:02 amChicago O'Hare Intl
$239
Find similar
American Airlines
Feb 19
ORD6:40 pmChicago O'Hare Intl
1h 43m
TYS9:23 pmKnoxville McGhee Tyson
Feb 22
TYS6:00 amKnoxville McGhee Tyson
5h 40m
1 stop
ORD10:40 amChicago O'Hare Intl
$243
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Chicago to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 23, 2025.
Use the filters below to find and compare flights from Chicago to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Mon 1/12

10:48 am-10:28 pm

1 stop10h 40m

Knoxville McGhee Tyson

Sun 1/18

1:39 pm-9:12 pm

1 stop8h 33m

$170

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Sun 1/11

8:27 pm-10:10 am

1 stop12h 43m

Knoxville McGhee Tyson

Sun 1/18

1:39 pm-9:12 pm

1 stop8h 33m

$178

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Tue 1/13

8:08 pm-3:03 pm

1 stop17h 55m

Knoxville McGhee Tyson

Sun 1/18

1:39 pm-9:12 pm

1 stop8h 33m

$179

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Mon 1/12

10:48 am-10:28 pm

1 stop10h 40m

Knoxville McGhee Tyson

Thu 1/15

1:39 pm-9:12 pm

1 stop8h 33m

$182

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Sat 1/10

8:27 pm-1:10 pm

1 stop15h 43m

Knoxville McGhee Tyson

Sun 1/18

1:39 pm-9:12 pm

1 stop8h 33m

$186

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Tue 2/17

6:00 pm-8:37 pm

Nonstop1h 37m

Knoxville McGhee Tyson

Tue 2/24

10:53 am-12:00 pm

Nonstop2h 07m

$189

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Sun 1/11

8:27 pm-10:10 am

1 stop12h 43m

Knoxville McGhee Tyson

Thu 1/15

1:39 pm-9:12 pm

1 stop8h 33m

$190

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Thu 1/22

1:26 pm-8:47 pm

1 stop6h 21m

Knoxville McGhee Tyson

Sun 1/25

5:40 am-9:53 am

1 stop5h 13m

$209

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Mon 1/5

5:31 pm-11:45 pm

1 stop5h 14m

Knoxville McGhee Tyson

Sun 1/11

7:30 am-12:48 pm

1 stop6h 18m

$224

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Thu 3/5

5:00 pm-10:10 pm

1 stop4h 10m

Knoxville McGhee Tyson

Mon 3/9

3:45 pm-10:00 pm

1 stop7h 15m

$317

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Chicago to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Chicago and Knoxville?

What is the cheapest month to fly to Knoxville?

The month of September is, on average, the cheapest month to fly to Knoxville from Chicago, with most prices found around $229. If you aren’t able to travel during the month of September, then book flights to Knoxville from Chicago during June instead. Flights to Knoxville in June, while not as cheap as those in September, still average around $244.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Chicago to Knoxville is on a Saturday. Travelers who choose to depart for Knoxville on a Saturday will often find tickets for as low as $261. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Chicago to Knoxville for around $319.

What is the cheapest time of day to depart on your flight to Knoxville?

At noon is the cheapest time of day to fly from Chicago to Knoxville when you can find flight prices for as low as $262. Flying to Knoxville at noon is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the afternoon when prices are around $297.

What is the cheapest Chicago to Knoxville McGhee Tyson flight route?

Fly from Chicago Midway to Knoxville McGhee Tyson for the best Chicago - Knoxville McGhee Tyson flight prices

How far in advance should I book a flight to Knoxville?

You are more likely to see cheaper flights to Knoxville from Chicago when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $314 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Chicago for as low as $224 on momondo.

What cabin class options are available on Chicago to Knoxville McGhee Tyson flights?

There are 4 cabin classes available to choose from on Chicago to Knoxville McGhee Tyson flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Chicago to Knoxville flights?

You could potentially save up to 19% on your flight if you consider stops on a Chicago to Knoxville flight.

How have Chicago to Knoxville flight prices changed over time?

As of December 2025, prices for Chicago to Knoxville flights are approximately 11% more expensive when compared to flights at the same time last year.

When to book flights from Chicago to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago to Knoxville (CHI to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago to Knoxville

Best Price Found

$91

Fastest flight time

1h 26m

Direct flights

Every day

Airports in Knoxville

1 airport
The best one-way flight to Knoxville from Chicago in the past 72 hours is $91. The best round-trip flight deal from Chicago to Knoxville found on momondo in the last 72 hours is $138.
The fastest flight from Chicago to Knoxville takes 1h 26m
Direct flights go from Chicago to Knoxville every day.
There is 1 airport in Knoxville. From Chicago there are direct flights to Knoxville McGhee Tyson (TYS).
Search flight deals

  • How far is Chicago to Knoxville McGhee Tyson by plane?

    There are 454.2 mi between Chicago and Knoxville McGhee Tyson. 1h 26m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Chicago to Knoxville McGhee Tyson Airport?

    Prices for flights from Chicago to Knoxville McGhee Tyson Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Chicago to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Chicago to Knoxville McGhee Tyson Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The required travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Chicago to Knoxville?

  • What is the most popular airline from Chicago to Knoxville?

Best airlines flying from Chicago to Knoxville

Compare and see reviews for airlines that fly from Chicago to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $82Free CancellationRating
7.2
701 reviews
Search Allegiant Air flights
American AirlinesPriceFrom $189Free CancellationRating
7.2
11,054 reviews
Search American Airlines flights
United AirlinesPriceFrom $192Free CancellationRating
7.4
9,105 reviews
Search United Airlines flights
DeltaPriceFrom $208Free CancellationRating
7.9
8,014 reviews
Search Delta flights

  • United Airlines Flights From Chicago to Knoxville

    United Airlines flies from Chicago to Knoxville around 17 times per week, with 9,105 momondo users rating the airline 7.4/10. The cheapest United Airlines deal from Chicago to Knoxville in the last 72 hours was $192 (round-trip), much lower than the average airfare cost of $330 for United Airlines flights on this route.

  • American Airlines Flights From Chicago to Knoxville

    The best American Airlines deal for Chicago to Knoxville flight tickets found on momondo in the last 72 hours was $189, round-trip. It should be noted that an average American Airlines flight deal for this route in this time was higher, at $304 round-trip. American Airlines operates 10 flights out of Chicago into Knoxville in an average week, so prices vary by time and availability. 11,054 American Airlines reviews by users on momondo have scored the airline at 7.2/10.

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Maryville
Crossville
Murphy
Alcoa
Oak Ridge
Newport
Lenoir City
Kodak
Dandridge
Jefferson City
Clinton
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Knoxville?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Chicago to Knoxville. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Chicago to Knoxville with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Knoxville from Chicago with this policy.

How can momondo help me find flights from Chicago to Knoxville?

momondo provides multiple filters to help you find the best flight to Knoxville from Chicago. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Chicago to Knoxville right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Knoxville from Chicago. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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