How many flights depart from Chicago to Knoxville on average per week?

The number of flights available between Chicago and Knoxville is 80 per week as of October 2025. The most frequent departure day is Thu, with 33% of weekly flights leaving on this day.

What is the cheapest airline that flies from Chicago to Knoxville McGhee Tyson?

Frontier, Allegiant Air, and American Airlines are the most popular carriers operating from Chicago to Knoxville McGhee Tyson

How many flights depart from Chicago to Knoxville on average per day?

11 flights are operational daily from Chicago to Knoxville as of October 2025. The most popular departure time for this route is 6:00PM, with 34% of flights per day taking off at noon.

What airlines fly to Knoxville?

American Airlines, United Airlines and Allegiant Air are the top three most popular airlines that fly to Knoxville from Chicago according to our data. American Airlines is the first choice among our users, with 51% of people opting to fly with this airline when traveling to Knoxville. Keep in mind that there are 4 different airlines that fly to Knoxville on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Chicago to Knoxville McGhee Tyson Airport?

Prices for flights from Chicago to Knoxville McGhee Tyson Airport are refreshed on a daily basis.

How many operators does momondo search for flights from Chicago to Knoxville McGhee Tyson Airport?

As of October 2025, there are 4 operators available to choose from for flights from Chicago to Knoxville McGhee Tyson Airport.

How old do you have to be to fly from Chicago to Knoxville McGhee Tyson Airport?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago to Knoxville McGhee Tyson Airport.

What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

The required travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$55 Cheap Flights from Chicago to Knoxville in 2025/26

Q: What is the typical price of a round-trip flight between Chicago and Knoxville?

Prices are currently low for flights on this route. Typical prices usually range from $198 to $338. The lowest price recently found on this route was $148.

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8:00 am - 11:14 pmMDW-TYS

14h 14m1 stop

2:02 pm - 2:37 pmTYS-MDW

1h 35mnonstop

$148Multiple Airlines

Find Deal

Mon, Nov 10 - Fri, Nov 14

4:12 pm - 6:37 pmMDW-TYS

1h 25mnonstop

6:42 pm - 9:35 pmTYS-MDW

27h 53m2 stops

$155Multiple Airlines

Find Deal

Mon, Nov 10 - Fri, Nov 14

2:11 pm - 4:36 pmMDW-TYS

1h 25mnonstop

6:18 pm - 6:54 pmTYS-MDW

1h 36mnonstop

$167Allegiant Air

Find Deal

Fri, Nov 21 - Wed, Nov 26

2:11 pm - 4:36 pmMDW-TYS

1h 25mnonstop

6:18 pm - 6:54 pmTYS-MDW

1h 36mnonstop

$174Allegiant Air

Find Deal

Mon, Nov 24 - Wed, Nov 26

8:04 pm - 10:55 pmORD-TYS

1h 51mnonstop

6:45 am - 7:46 amTYS-ORD

2h 01mnonstop

$189United Airlines

Find Deal

Fri, Nov 21 - Mon, Nov 24

7:29 pm - 10:09 pmORD-TYS

1h 40mnonstop

4:44 pm - 5:55 pmTYS-ORD

2h 11mnonstop

$194American Airlines

Find Deal

Sat, Jan 10 - Sat, Jan 31

5:50 pm - 8:33 pmORD-TYS

1h 43mnonstop

10:50 am - 11:53 amTYS-ORD

2h 03mnonstop

$204United Airlines

Find Deal

Sat, Nov 15 - Mon, Nov 24

7:10 am - 4:19 pmORD-TYS

8h 09m1 stop

5:30 am - 10:08 amTYS-ORD

5h 38m1 stop

$209Delta

Find Deal

Thu, Jan 22 - Tue, Jan 27

12:47 pm - 7:02 pmMDW-TYS

5h 15m1 stop

5:35 am - 9:52 amTYS-MDW

5h 17m1 stop

$209Delta

Find Deal

Wed, Nov 19 - Sun, Nov 23

3:08 pm - 5:58 pmORD-TYS

1h 50mnonstop

6:29 pm - 7:33 pmTYS-ORD

2h 04mnonstop

$223American Airlines

Find Deal

Thu, Dec 11 - Sun, Dec 14

United Airlines flights from Chicago to Knoxville

Our best United Airlines deals on Chicago to Knoxville flight tickets

United Airlines

Nov 21

ORD8:04 pmChicago O'Hare Intl

1h 51m

TYS10:55 pmKnoxville McGhee Tyson

Nov 24

TYS6:45 amKnoxville McGhee Tyson

2h 01m

ORD7:46 amChicago O'Hare Intl

$189

Find similar

United Airlines

Nov 15

ORD5:50 pmChicago O'Hare Intl

1h 43m

TYS8:33 pmKnoxville McGhee Tyson

Nov 24

TYS10:50 amKnoxville McGhee Tyson

2h 03m

ORD11:53 amChicago O'Hare Intl

$204

Find similar

United Airlines

Nov 12

ORD7:20 amChicago O'Hare Intl

1h 45m

TYS10:05 amKnoxville McGhee Tyson

Nov 15

TYS8:26 amKnoxville McGhee Tyson

2h 04m

ORD9:30 amChicago O'Hare Intl

$219

Find similar

Frontier flights from Chicago to Knoxville

Our best Frontier deals on Chicago to Knoxville flight tickets

Frontier

Dec 11

ORD7:00 amChicago O'Hare Intl

7h 57m

1 stop

TYS3:57 pmKnoxville McGhee Tyson

Dec 14

TYS4:52 pmKnoxville McGhee Tyson

8h 20m

1 stop

ORD12:12 amChicago O'Hare Intl

$163

Find similar

Frontier

Dec 4

ORD7:00 amChicago O'Hare Intl

7h 57m

1 stop

TYS3:57 pmKnoxville McGhee Tyson

Dec 7

TYS4:52 pmKnoxville McGhee Tyson

8h 20m

1 stop

ORD12:12 amChicago O'Hare Intl

$202

Find similar

Frontier

Nov 8

MDW1:37 pmChicago Midway

27h 45m

2 stops

TYS6:22 pmKnoxville McGhee Tyson

Nov 13

TYS7:17 pmKnoxville McGhee Tyson

17h 13m

1 stop

MDW11:30 amChicago Midway

$311

Find similar

Fly from

Fly to

Route

Depart

Return

Price

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Mon 11/10

8:00 am-11:14 pm

1 stop14h 14m

Knoxville McGhee Tyson

Fri 11/14

2:02 pm-2:37 pm

Nonstop1h 35m

$148

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Mon 11/10

4:12 pm-6:37 pm

Nonstop1h 25m

Knoxville McGhee Tyson

Fri 11/14

6:42 pm-9:35 pm

2 stops27h 53m

$155

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Fri 11/21

2:11 pm-4:36 pm

Nonstop1h 25m

Knoxville McGhee Tyson

Wed 11/26

6:18 pm-6:54 pm

Nonstop1h 36m

$167

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Mon 11/24

2:11 pm-4:36 pm

Nonstop1h 25m

Knoxville McGhee Tyson

Wed 11/26

6:18 pm-6:54 pm

Nonstop1h 36m

$174

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Fri 11/21

8:04 pm-10:55 pm

Nonstop1h 51m

Knoxville McGhee Tyson

Mon 11/24

6:45 am-7:46 am

Nonstop2h 01m

$189

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Sat 1/10

7:29 pm-10:09 pm

Nonstop1h 40m

Knoxville McGhee Tyson

Sat 1/31

4:44 pm-5:55 pm

Nonstop2h 11m

$194

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Sat 11/15

5:50 pm-8:33 pm

Nonstop1h 43m

Knoxville McGhee Tyson

Mon 11/24

10:50 am-11:53 am

Nonstop2h 03m

$204

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Thu 1/22

7:10 am-4:19 pm

1 stop8h 09m

Knoxville McGhee Tyson

Tue 1/27

5:30 am-10:08 am

1 stop5h 38m

$209

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Wed 11/19

12:47 pm-7:02 pm

1 stop5h 15m

Knoxville McGhee Tyson

Sun 11/23

5:35 am-9:52 am

1 stop5h 17m

$209

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Thu 12/11

3:08 pm-5:58 pm

Nonstop1h 50m

Knoxville McGhee Tyson

Sun 12/14

6:29 pm-7:33 pm

Nonstop2h 04m

$223

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How to get the cheapest flight ticket from Chicago to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the typical price of a round-trip flight between Chicago and Knoxville?

What is the cheapest month to fly to Knoxville?

The month of September is, on average, the cheapest month to fly to Knoxville from Chicago, with most prices found around $229. If you aren’t able to travel during the month of September, then book flights to Knoxville from Chicago during January instead. Flights to Knoxville in January, while not as cheap as those in September, still average around $244.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Chicago to Knoxville is on a Wednesday. Travelers who choose to depart for Knoxville on a Wednesday will often find tickets for as low as $264. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Chicago to Knoxville for around $321.

What is the cheapest time of day to depart on your flight to Knoxville?

At noon is the cheapest time of day to fly from Chicago to Knoxville when you can find flight prices for as low as $264. Flying to Knoxville at noon is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the morning when prices are around $292.

What is the cheapest Chicago to Knoxville McGhee Tyson flight route?

Fly from Chicago Midway to Knoxville McGhee Tyson for the best Chicago - Knoxville McGhee Tyson flight prices

How far in advance should I book a flight to Knoxville?

You are more likely to see cheaper flights to Knoxville from Chicago when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $306 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Chicago for as low as $224 on momondo.

What cabin class options are available on Chicago to Knoxville McGhee Tyson flights?

There are 4 cabin classes available to choose from on Chicago to Knoxville McGhee Tyson flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Chicago to Knoxville flights?

No. A direct flight is the cheapest option for a flight between Chicago to Knoxville.

How have Chicago to Knoxville flight prices changed over time?

As of October 2025, prices for Chicago to Knoxville flights are approximately 30% more expensive when compared to flights at the same time last year.

When to book flights from Chicago to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago to Knoxville according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Chicago to Knoxville (CHI to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago to Knoxville

Best Price Found	$58
Fastest flight time	1h 25m
Direct flights	Every day
Airports in Knoxville	1 airport

The best one-way flight to Knoxville from Chicago in the past 72 hours is $58. The best round-trip flight deal from Chicago to Knoxville found on momondo in the last 72 hours is $130.

The fastest flight from Chicago to Knoxville takes 1h 25m

Direct flights go from Chicago to Knoxville every day.

There is 1 airport near Knoxville: Knoxville McGhee Tyson (TYS)

Search flight deals

How far is Chicago to Knoxville McGhee Tyson by plane?
There are 454.2 mi between Chicago and Knoxville McGhee Tyson. 1h 25m is a normal flight duration for this route.
When did momondo last update prices for flights from Chicago to Knoxville McGhee Tyson Airport?
Prices for flights from Chicago to Knoxville McGhee Tyson Airport are refreshed on a daily basis.
How many operators does momondo search for flights from Chicago to Knoxville McGhee Tyson Airport?
As of October 2025, there are 4 operators available to choose from for flights from Chicago to Knoxville McGhee Tyson Airport.
How old do you have to be to fly from Chicago to Knoxville McGhee Tyson Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago to Knoxville McGhee Tyson Airport.
What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?
The required travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from Chicago to Knoxville?
Based on momondo bookings for flights between Chicago and Knoxville, the leading plane model is Canadair (Bombardier) Regional Jet CRJ-550, making up 18.57% of the total bookings. Other popular models include Canadair (Bombardier) Regional Jet 700 with 18.32%, Embraer 175 (Enhanced Winglets) with 16.11%, and Embraer 170 with 13.78%.
What is the most popular airline from Chicago to Knoxville?
Based on momondo bookings for flights between Chicago and Knoxville, the leading airline is American Airlines, making up 50% of the total bookings. Other popular airlines include United Airlines with 32%, Allegiant Air with 16%, and Delta with 1%.

Best airlines flying from Chicago to Knoxville

Compare and see reviews for airlines that fly from Chicago to Knoxville with momondo

Airline	Rating	Free Cancellation	Price
Allegiant Air	PriceFrom $80	Free Cancellation	Rating 7.2 694 reviews	Search Allegiant Air flights
American Airlines	PriceFrom $189	Free Cancellation	Rating 7.2 11,035 reviews	Search American Airlines flights
United Airlines	PriceFrom $189	Free Cancellation	Rating 7.4 8,998 reviews	Search United Airlines flights
Delta	PriceFrom $193	Free Cancellation	Rating 7.9 7,998 reviews	Search Delta flights

United Airlines Flights From Chicago to Knoxville
United Airlines flies from Chicago to Knoxville around 15 times per week, with 8,998 momondo users rating the airline 7.4/10. The cheapest United Airlines deal from Chicago to Knoxville in the last 72 hours was $189 (round-trip), much lower than the average airfare cost of $329 for United Airlines flights on this route.
American Airlines Flights From Chicago to Knoxville
The best American Airlines deal for Chicago to Knoxville flight tickets found on momondo in the last 72 hours was $189, round-trip. It should be noted that an average American Airlines flight deal for this route in this time was higher, at $301 round-trip. American Airlines operates 8 flights out of Chicago into Knoxville in an average week, so prices vary by time and availability. 11,035 American Airlines reviews by users on momondo have scored the airline at 7.2/10.

Pigeon Forge

Gatlinburg

Cherokee

Bryson City

Morristown

Corbin

Crossville

Maryville

Murphy

Alcoa

Oak Ridge

Lenoir City

Newport

Kodak

Dandridge

Clinton

Jefferson City

Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Knoxville?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Chicago to Knoxville. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Chicago to Knoxville with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Knoxville from Chicago with this policy.

How can momondo help me find flights from Chicago to Knoxville?

momondo provides multiple filters to help you find the best flight to Knoxville from Chicago. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Chicago to Knoxville right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Knoxville from Chicago. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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Cheap flights from Chicago to Knoxville from $55

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago to Knoxville departing on 12/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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How to get the cheapest flight ticket from Chicago to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Chicago and Knoxville?

What is the cheapest month to fly to Knoxville?

What is the cheapest day to depart on your flight to Knoxville?

What is the cheapest time of day to depart on your flight to Knoxville?

What is the cheapest Chicago to Knoxville McGhee Tyson flight route?

Fly from Chicago Midway to Knoxville McGhee Tyson for the best Chicago - Knoxville McGhee Tyson flight prices

How far in advance should I book a flight to Knoxville?

What cabin class options are available on Chicago to Knoxville McGhee Tyson flights?

There are 4 cabin classes available to choose from on Chicago to Knoxville McGhee Tyson flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Chicago to Knoxville flights?

No. A direct flight is the cheapest option for a flight between Chicago to Knoxville.

How have Chicago to Knoxville flight prices changed over time?

As of October 2025, prices for Chicago to Knoxville flights are approximately 30% more expensive when compared to flights at the same time last year.

What is the cheapest airline that flies from Chicago to Knoxville McGhee Tyson?

Frontier, Allegiant Air, and American Airlines are the most popular carriers operating from Chicago to Knoxville McGhee Tyson

What airlines fly to Knoxville?

How many flights depart from Chicago to Knoxville on average per day?

11 flights are operational daily from Chicago to Knoxville as of October 2025. The most popular departure time for this route is 6:00PM, with 34% of flights per day taking off at noon.

How many flights depart from Chicago to Knoxville on average per week?

The number of flights available between Chicago and Knoxville is 80 per week as of October 2025. The most frequent departure day is Thu, with 33% of weekly flights leaving on this day.

When to book flights from Chicago to Knoxville

Cheap Chicago to Knoxville (CHI to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago to Knoxville

Best Price Found

Fastest flight time

Direct flights

Airports in Knoxville

How far is Chicago to Knoxville McGhee Tyson by plane?

When did momondo last update prices for flights from Chicago to Knoxville McGhee Tyson Airport?

How many operators does momondo search for flights from Chicago to Knoxville McGhee Tyson Airport?

How old do you have to be to fly from Chicago to Knoxville McGhee Tyson Airport?

What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

What is the most popular plane model from Chicago to Knoxville?

What is the most popular airline from Chicago to Knoxville?

Best airlines flying from Chicago to Knoxville

Compare and see reviews for airlines that fly from Chicago to Knoxville with momondo

United Airlines Flights From Chicago to Knoxville

American Airlines Flights From Chicago to Knoxville

Traveling to a place near Knoxville?

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Knoxville?

Can I find flights from Chicago to Knoxville with flexible booking policies on momondo?

How can momondo help me find flights from Chicago to Knoxville?

I’m not ready to book a flight from Chicago to Knoxville right now. Can momondo alert me if prices change?

An easier way to manage your Knoxville trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing Tennessee