Cheap flights from Charlotte to Panama City from $149

The cheapest month to fly to Panama City, Florida from Charlotte is in January. Flight prices, which tend to average around $339, are often lower during this time because this is during the off-season. The month of February is another great option to travel to Panama City, Florida, with average flight prices from Charlotte averaging around $359.

Our data shows that Monday is the least expensive day to fly to Panama City, Florida. Tickets to fly out on this day can be as low as $381. On the other hand, Thursday is the most expensive day to depart from Charlotte because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $480.

Fly from Charlotte Douglas to Panama City NW Florida Beaches for the best Charlotte Douglas - Panama City NW Florida Beaches flight prices

You are more likely to see cheaper flights to Panama City, Florida from Charlotte when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City, Florida for around $430 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City, Florida from Charlotte for as low as $326 on momondo.

There are 3 cabin classes available to choose from on Charlotte to Panama City, Florida flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 56% on your flight if you consider stops on a Charlotte to Panama City, Florida flight.

Southwest is the most popular carrier operating from Charlotte Douglas to Panama City NW Florida Beaches

American Airlines, Delta and Southwest are the top three most popular airlines that fly to Panama City, Florida from Charlotte according to our data. American Airlines is the first choice among our users, with 75% of people opting to fly with this airline when traveling to Panama City, Florida. Keep in mind that there are 3 different airlines that fly to Panama City, Florida on a routine basis, so you have a few additional options to choose from.

As of August 2026, 2 flights take off from Charlotte and land in Panama City, Florida each day. The most common flight departure time for this route is 10:00AM, with 35% of daily flights taking off at noon.

The number of flights available between Charlotte and Panama City, Florida is 18 per week as of August 2026. The most frequent departure day is Mon, with 17% of weekly flights leaving on this day.