Cheap flights from Central America to Missouri from $146

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Central America to Missouri departing on 12/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
2:27 pm - 9:40 amGUA-STL
19h 13m1 stop
Frontier Logo
10:48 am - 1:22 pmSTL-GUA
26h 34m1 stop
$207Frontier
Find Deal
Mon, Dec 22 - Tue, Dec 30
Multiple Airlines Logo
12:20 pm - 10:33 pmGUA-STL
10h 13m1 stop
Multiple Airlines Logo
10:48 am - 1:22 pmSTL-GUA
26h 34m1 stop
$229Multiple Airlines
Find Deal
Sat, Dec 20 - Tue, Dec 30
Multiple Airlines Logo
3:00 pm - 7:42 pmGUA-STL
28h 42m1 stop
Multiple Airlines Logo
10:48 am - 1:22 pmSTL-GUA
26h 34m1 stop
$231Multiple Airlines
Find Deal
Thu, Dec 18 - Tue, Dec 30
United Airlines Logo
6:30 am - 10:58 pmSJO-STL
16h 28m2 stops
United Airlines Logo
6:00 am - 6:16 pmSTL-SJO
12h 16m1 stop
$303United Airlines
Find Deal
Tue, Feb 3 - Wed, Feb 11
Spirit Airlines Logo
1:39 pm - 5:10 pmGUA-MCI
27h 31m1 stop
Spirit Airlines Logo
6:15 pm - 12:34 pmMCI-GUA
18h 19m1 stop
$309Spirit Airlines
Find Deal
Wed, Dec 24 - Wed, Dec 31
United Airlines Logo
2:05 pm - 10:59 pmSJO-STL
8h 54m1 stop
United Airlines Logo
10:10 am - 8:39 pmSTL-SJO
10h 29m1 stop
$312United Airlines
Find Deal
Thu, Feb 26 - Mon, Mar 2
Spirit Airlines Logo
3:14 pm - 5:10 pmSAP-MCI
25h 56m1 stop
Spirit Airlines Logo
6:15 pm - 2:13 pmMCI-SAP
19h 58m1 stop
$319Spirit Airlines
Find Deal
Thu, Dec 18 - Mon, Jan 5
American Airlines Logo
2:35 pm - 10:39 amSJO-MCI
19h 04m1 stop
American Airlines Logo
8:02 pm - 1:09 pmMCI-SJO
18h 07m1 stop
$391American Airlines
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Tue, Apr 28 - Sat, May 9
American Airlines Logo
7:10 am - 9:44 pmSJO-MCI
13h 34m2 stops
American Airlines Logo
8:02 pm - 1:09 pmMCI-SJO
18h 07m1 stop
$395American Airlines
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Tue, Apr 28 - Sat, May 9
Delta Logo
2:20 pm - 8:07 amPTY-STL
17h 47m1 stop
Delta Logo
6:00 am - 12:55 pmSTL-PTY
6h 55m1 stop
$546Delta
Find Deal
Fri, May 1 - Tue, May 5

Delta flights from Central America to Missouri

Our best Delta deals on Central America to Missouri flight tickets
Delta
Feb 3
SJO7:00 amSan José Juan Santamaria Intl
13h 39m
1 stop
STL8:39 pmLambert-St Louis
Feb 9
STL9:59 amLambert-St Louis
12h 16m
1 stop
SJO10:15 pmSan José Juan Santamaria Intl
Delta
Nov 20
SJO7:00 amSan José Juan Santamaria Intl
10h 57m
1 stop
STL5:57 pmLambert-St Louis
Nov 30
STL9:33 amLambert-St Louis
12h 34m
1 stop
SJO10:07 pmSan José Juan Santamaria Intl
Delta
Nov 25
SJO7:00 amSan José Juan Santamaria Intl
11h 35m
1 stop
STL6:35 pmLambert-St Louis
Nov 29
STL6:00 amLambert-St Louis
16h 07m
1 stop
SJO10:07 pmSan José Juan Santamaria Intl

United Airlines flights from Central America to Missouri

Our best United Airlines deals on Central America to Missouri flight tickets
United Airlines
Feb 26
SJO2:05 pmSan José Juan Santamaria Intl
8h 54m
1 stop
STL10:59 pmLambert-St Louis
Mar 2
STL10:10 amLambert-St Louis
10h 29m
1 stop
SJO8:39 pmSan José Juan Santamaria Intl
United Airlines
Jan 31
SJO6:30 amSan José Juan Santamaria Intl
29h 59m
2 stops
STL12:29 pmLambert-St Louis
Feb 10
STL6:40 pmLambert-St Louis
23h 36m
2 stops
SJO6:16 pmSan José Juan Santamaria Intl
United Airlines
Feb 2
SJO6:30 amSan José Juan Santamaria Intl
32h 00m
2 stops
STL2:30 pmLambert-St Louis
Feb 10
STL6:40 pmLambert-St Louis
23h 36m
2 stops
SJO6:16 pmSan José Juan Santamaria Intl

momondo Fare Finder

 
Customize your flight search to find flights from Central America to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 13, 2025.
Use the filters below to find and compare flights from Central America to Missouri that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Guatemala CitySt. Louis

GUA - STL

GUASTL

Guatemala City La Aurora

Mon 12/22

2:27 pm-9:40 am

1 stop19h 13m

Lambert-St Louis

Tue 12/30

10:48 am-1:22 pm

1 stop26h 34m

$207

Guatemala CitySt. Louis

GUA - STL

GUASTL

Guatemala City La Aurora

Sat 12/20

12:20 pm-10:33 pm

1 stop10h 13m

Lambert-St Louis

Tue 12/30

10:48 am-1:22 pm

1 stop26h 34m

$229

Guatemala CitySt. Louis

GUA - STL

GUASTL

Guatemala City La Aurora

Thu 12/18

3:00 pm-7:42 pm

1 stop28h 42m

Lambert-St Louis

Tue 12/30

10:48 am-1:22 pm

1 stop26h 34m

$231

San JoséSt. Louis

SJO - STL

SJOSTL

San José Juan Santamaria Intl

Tue 2/3

6:30 am-10:58 pm

2 stops16h 28m

Lambert-St Louis

Wed 2/11

6:00 am-6:16 pm

1 stop12h 16m

$303

Guatemala CityKansas City

GUA - MCI

GUAMCI

Guatemala City La Aurora

Wed 12/24

1:39 pm-5:10 pm

1 stop27h 31m

Kansas City

Wed 12/31

6:15 pm-12:34 pm

1 stop18h 19m

$309

San JoséSt. Louis

SJO - STL

SJOSTL

San José Juan Santamaria Intl

Thu 2/26

2:05 pm-10:59 pm

1 stop8h 54m

Lambert-St Louis

Mon 3/2

10:10 am-8:39 pm

1 stop10h 29m

$312

San Pedro SulaKansas City

SAP - MCI

SAPMCI

San Pedro Sula Ramon Villeda

Thu 12/18

3:14 pm-5:10 pm

1 stop25h 56m

Kansas City

Mon 1/5

6:15 pm-2:13 pm

1 stop19h 58m

$319

San JoséKansas City

SJO - MCI

SJOMCI

San José Juan Santamaria Intl

Tue 4/28

2:35 pm-10:39 am

1 stop19h 04m

Kansas City

Sat 5/9

8:02 pm-1:09 pm

1 stop18h 07m

$391

San JoséKansas City

SJO - MCI

SJOMCI

San José Juan Santamaria Intl

Tue 4/28

7:10 am-9:44 pm

2 stops13h 34m

Kansas City

Sat 5/9

8:02 pm-1:09 pm

1 stop18h 07m

$395

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Fri 5/1

2:20 pm-8:07 am

1 stop17h 47m

Lambert-St Louis

Tue 5/5

6:00 am-12:55 pm

1 stop6h 55m

$546

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Missouri from

How to get the cheapest flight ticket from Central America to Missouri

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Missouri?

In general, October is the cheapest month to fly from Central America to Missouri. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $362. If you aren’t able to travel to Missouri during the month of October, then flying in August is also cheap. Prices for this month can be found on momondo for an average of $391.

What is the cheapest day to depart on your flight to Missouri?

The cheapest day to depart from Central America to Missouri is on a Tuesday when prices can be found for as low as $420. Flights from Central America to Missouri on a Monday will generally be more expensive and average around $690. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Missouri?

According to our data, the cheapest time of day to fly to Missouri is in the morning. momondo users have found flights departing from Central America to Missouri in the morning for as low as $479. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights to Missouri are more costly in the afternoon, with an average ticket price of $561. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

Can stopping save me money on Central America to Missouri flights?

You could potentially save up to 7% on your flight if you consider stops on a Central America to Missouri flight.

Cheap Central America to Missouri flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Central America to Missouri

Direct flights

None
There are no direct flights from Central America to Missouri. There are no popular flight routes from Central America to Missouri.
  • When did momondo last update prices for flights from Central America to Missouri?

    Prices for flights from Central America to Missouri were last updated today.

  • How many operators does momondo search for flights from Central America to Missouri?

  • How old do you have to be to fly from Central America to Missouri?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Central America to Missouri.

  • What documentation or ID do you need to fly to Missouri?

    The travel and health documents required for your trip to Missouri can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Missouri. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Central America to Missouri

Compare and see reviews for airlines that fly from Central America to Missouri with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $149Free CancellationRating
6.3
8,139 reviews
Search Spirit Airlines flights
United AirlinesPriceFrom $252Free CancellationRating
7.4
9,015 reviews
Search United Airlines flights
American AirlinesPriceFrom $274Free CancellationRating
7.2
11,049 reviews
Search American Airlines flights
DeltaPriceFrom $292Free CancellationRating
7.9
8,009 reviews
Search Delta flights
SouthwestPriceFrom $293Free CancellationRating
8.0
4,235 reviews
Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Central America to Missouri?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Central America to Missouri for you.

Can I find flights from Central America to Missouri with flexible booking policies on momondo?

All flight searches from Central America to Missouri on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Central America to Missouri?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Central America to Missouri.

I’m not ready to book a flight from Central America to Missouri right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Central America to Missouri flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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1 adult
Sat 12/13
Sat 12/20

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