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Cheap flights from Buffalo to Myrtle Beach from $125

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Buffalo to Myrtle Beach departing on 2/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Buffalo to Myrtle Beach

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
7:17 pm - 2:55 pm
BUF
-
MYR
19h 38m
2 stops
Multiple Airlines Logo
12:39 pm - 10:49 am
MYR
-
BUF
22h 10m
1 stop
$238Multiple Airlines
Tue, Feb 24 - Thu, Mar 5
Multiple Airlines Logo
4:37 pm - 9:50 am
BUF
-
MYR
17h 13m
1 stop
Multiple Airlines Logo
12:39 pm - 10:49 am
MYR
-
BUF
22h 10m
1 stop
$241Multiple Airlines
Sat, Feb 21 - Thu, Mar 5
Multiple Airlines Logo
4:37 pm - 9:50 am
BUF
-
MYR
17h 13m
1 stop
Multiple Airlines Logo
9:09 am - 11:05 am
MYR
-
BUF
25h 56m
2 stops
$247Multiple Airlines
Sat, Feb 21 - Fri, Feb 27
Multiple Airlines Logo
4:37 pm - 9:50 am
BUF
-
MYR
17h 13m
1 stop
Multiple Airlines Logo
11:57 am - 1:24 pm
MYR
-
BUF
25h 27m
2 stops
$249Multiple Airlines
Sat, Feb 21 - Sat, Feb 28
Multiple Airlines Logo
4:37 pm - 9:50 am
BUF
-
MYR
17h 13m
1 stop
Multiple Airlines Logo
9:09 am - 12:53 pm
MYR
-
BUF
27h 44m
2 stops
$252Multiple Airlines
Sat, Feb 21 - Sun, Mar 1
Multiple Airlines Logo
1:48 pm - 2:55 pm
BUF
-
MYR
25h 07m
2 stops
Multiple Airlines Logo
12:39 pm - 10:49 am
MYR
-
BUF
22h 10m
1 stop
$259Multiple Airlines
Mon, Feb 23 - Thu, Mar 5
Multiple Airlines Logo
4:37 pm - 9:50 am
BUF
-
MYR
17h 13m
1 stop
Multiple Airlines Logo
10:09 am - 12:53 pm
MYR
-
BUF
26h 44m
2 stops
$260Multiple Airlines
Sat, Feb 21 - Sun, Mar 1
Multiple Airlines Logo
9:47 pm - 10:00 am
BUF
-
MYR
12h 13m
1 stop
Multiple Airlines Logo
12:05 pm - 10:49 am
MYR
-
BUF
22h 44m
1 stop
$264Multiple Airlines
Sun, Mar 22 - Thu, Mar 26
Multiple Airlines Logo
4:37 pm - 9:50 am
BUF
-
MYR
17h 13m
1 stop
Multiple Airlines Logo
10:09 am - 11:39 am
MYR
-
BUF
25h 30m
2 stops
$265Multiple Airlines
Sat, Feb 21 - Wed, Mar 4
Multiple Airlines Logo
7:17 pm - 2:55 pm
BUF
-
MYR
19h 38m
2 stops
Multiple Airlines Logo
3:20 pm - 6:21 pm
MYR
-
BUF
27h 01m
1 stop
$267Multiple Airlines
Tue, Feb 24 - Mon, Mar 2

American Airlines flights from Buffalo to Myrtle Beach

Our best American Airlines deals on Buffalo to Myrtle Beach flight tickets
American Airlines
Feb 26
BUF7:41 pmBuffalo
4h 14m
1 stop
MYR11:55 pmMyrtle Beach Intl
Mar 7
MYR9:10 amMyrtle Beach Intl
6h 44m
2 stops
BUF3:54 pmBuffalo
$338
American Airlines
Jan 17
BUF5:16 amBuffalo
6h 34m
1 stop
MYR11:50 amMyrtle Beach Intl
Jan 19
MYR7:19 pmMyrtle Beach Intl
4h 22m
1 stop
BUF11:41 pmBuffalo
$988
American Airlines
Jan 17
BUF12:35 pmBuffalo
8h 19m
2 stops
MYR8:54 pmMyrtle Beach Intl
Jan 19
MYR7:19 pmMyrtle Beach Intl
4h 22m
1 stop
BUF11:41 pmBuffalo
$1,042

Southwest flights from Buffalo to Myrtle Beach

Our best Southwest deals on Buffalo to Myrtle Beach flight tickets
Southwest
Feb 10
BUF3:45 pmBuffalo
4h 00m
1 stop
MYR7:45 pmMyrtle Beach Intl
Feb 17
MYR8:20 amMyrtle Beach Intl
3h 35m
1 stop
BUF11:55 amBuffalo
$297
Southwest
Feb 10
BUF7:30 amBuffalo
12h 15m
2 stops
MYR7:45 pmMyrtle Beach Intl
Feb 17
MYR8:20 amMyrtle Beach Intl
6h 35m
1 stop
BUF2:55 pmBuffalo
$302
Southwest
Feb 10
BUF7:30 amBuffalo
12h 15m
2 stops
MYR7:45 pmMyrtle Beach Intl
Feb 17
MYR10:35 amMyrtle Beach Intl
8h 05m
2 stops
BUF6:40 pmBuffalo
$311

momondo Fare Finder

 
Customize your flight search to find flights from Buffalo to Myrtle Beach that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 15, 2026.
Use the filters below to find and compare flights from Buffalo to Myrtle Beach that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

BuffaloMyrtle Beach

BUF - MYR

BUFMYR

Buffalo

Tue 2/24

7:17 pm-2:55 pm

2 stops19h 38m

Myrtle Beach Intl

Thu 3/5

12:39 pm-10:49 am

1 stop22h 10m

$238

BuffaloMyrtle Beach

BUF - MYR

BUFMYR

Buffalo

Sat 2/21

4:37 pm-9:50 am

1 stop17h 13m

Myrtle Beach Intl

Thu 3/5

12:39 pm-10:49 am

1 stop22h 10m

$241

BuffaloMyrtle Beach

BUF - MYR

BUFMYR

Buffalo

Sat 2/21

4:37 pm-9:50 am

1 stop17h 13m

Myrtle Beach Intl

Fri 2/27

9:09 am-11:05 am

2 stops25h 56m

$247

BuffaloMyrtle Beach

BUF - MYR

BUFMYR

Buffalo

Sat 2/21

4:37 pm-9:50 am

1 stop17h 13m

Myrtle Beach Intl

Sat 2/28

11:57 am-1:24 pm

2 stops25h 27m

$249

BuffaloMyrtle Beach

BUF - MYR

BUFMYR

Buffalo

Sat 2/21

4:37 pm-9:50 am

1 stop17h 13m

Myrtle Beach Intl

Sun 3/1

9:09 am-12:53 pm

2 stops27h 44m

$252

BuffaloMyrtle Beach

BUF - MYR

BUFMYR

Buffalo

Mon 2/23

1:48 pm-2:55 pm

2 stops25h 07m

Myrtle Beach Intl

Thu 3/5

12:39 pm-10:49 am

1 stop22h 10m

$259

BuffaloMyrtle Beach

BUF - MYR

BUFMYR

Buffalo

Sat 2/21

4:37 pm-9:50 am

1 stop17h 13m

Myrtle Beach Intl

Sun 3/1

10:09 am-12:53 pm

2 stops26h 44m

$260

BuffaloMyrtle Beach

BUF - MYR

BUFMYR

Buffalo

Sun 3/22

9:47 pm-10:00 am

1 stop12h 13m

Myrtle Beach Intl

Thu 3/26

12:05 pm-10:49 am

1 stop22h 44m

$264

BuffaloMyrtle Beach

BUF - MYR

BUFMYR

Buffalo

Sat 2/21

4:37 pm-9:50 am

1 stop17h 13m

Myrtle Beach Intl

Wed 3/4

10:09 am-11:39 am

2 stops25h 30m

$265

BuffaloMyrtle Beach

BUF - MYR

BUFMYR

Buffalo

Tue 2/24

7:17 pm-2:55 pm

2 stops19h 38m

Myrtle Beach Intl

Mon 3/2

3:20 pm-6:21 pm

1 stop27h 01m

$267

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Myrtle Beach from

How to get the cheapest flight ticket from Buffalo to Myrtle Beach

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Myrtle Beach?

In general, September is the cheapest month to fly from Buffalo to Myrtle Beach. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $296. If you are unable to visit Myrtle Beach during the month of September, then departing from Buffalo during the month October is also very affordable. Most momondo users find prices during this month for around $301.

How far in advance should I book a flight to Myrtle Beach?

You are more likely to see cheaper flights to Myrtle Beach from Buffalo when booking weeks ahead of your departure date. In general, you can expect to find flights to Myrtle Beach for around $352 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Myrtle Beach from Buffalo for as low as $300 on momondo.

How have Buffalo to Myrtle Beach flight prices changed over time?

As of January 2026, prices for Buffalo to Myrtle Beach flights are approximately 31% cheaper when compared to flights at the same time last year.

When to book flights from Buffalo to Myrtle Beach

Are you open to changing your travel dates? Check out the ideal times to fly from Buffalo to Myrtle Beach according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Buffalo to Myrtle Beach (BUF to MYR) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Buffalo to Myrtle Beach

Fastest flight time

3h 30m

Direct flights

None
The fastest flight from Buffalo to Myrtle Beach takes 3h 30m
There are no direct flights from Buffalo to Myrtle Beach. There are no popular flight routes from Buffalo to Myrtle Beach.
Search flight deals

  • How far is Buffalo to Myrtle Beach Intl by plane?

    Buffalo and Myrtle Beach Intl are 635.0 mi apart from one another. Flights usually cover this in 3h 30m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Buffalo Airport to Myrtle Beach Intl Airport?

    Prices for flights from Buffalo Airport to Myrtle Beach Intl Airport are updated daily.

  • How many operators does momondo search for flights from Buffalo Airport to Myrtle Beach Intl Airport?

  • How old do you have to be to fly from Buffalo Airport to Myrtle Beach Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Buffalo Airport to Myrtle Beach Intl Airport.

  • What documentation or ID do you need to fly to Myrtle Beach Intl Airport?

    The travel and health documents required for your trip to Myrtle Beach Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Myrtle Beach Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Buffalo to Myrtle Beach?

Best airlines flying from Buffalo to Myrtle Beach

Compare and see reviews for airlines that fly from Buffalo to Myrtle Beach with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $191Free CancellationRating
7.9
8,051 reviews
Search Delta flights
American AirlinesPriceFrom $232Free CancellationRating
7.2
11,136 reviews
Search American Airlines flights
SouthwestPriceFrom $275Free CancellationRating
8.0
4,258 reviews
Search Southwest flights

Traveling to a place near Myrtle Beach?

Book flights to Myrtle Beach if you plan to visit one of these locations
North Myrtle Beach
Pawleys Island
Sunset Beach
Ocean Isle Beach
Murrells Inlet
Garden City Beach
Surfside Beach
Conway
Little River
Georgetown

Why use momondo?

Why should I use momondo to find a flight deal from Buffalo to Myrtle Beach?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Myrtle Beach from Buffalo.

Can I find flights from Buffalo to Myrtle Beach with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Myrtle Beach from Buffalo with this policy.

How can momondo help me find flights from Buffalo to Myrtle Beach?

Once all potential Buffalo to Myrtle Beach flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Buffalo to Myrtle Beach right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Buffalo to Myrtle Beach flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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