What is the cheapest airline that flies from Buffalo to Missouri?

American Airlines, Frontier, and Southwest are the most popular carriers operating from Buffalo to Missouri

What airlines fly to Missouri?

American Airlines, Delta and Southwest are the top three most popular airlines that fly to Missouri from Buffalo according to our data. American Airlines is the first choice among our users, with 40% of people opting to fly with this airline when traveling to Missouri. Keep in mind that there are 4 different airlines that fly to Missouri on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Buffalo Airport to Missouri?

Prices for flights from Buffalo Airport to Missouri are updated daily.

How many operators does momondo search for flights from Buffalo Airport to Missouri?

As of February 2026, there are 4 operators available to choose from for flights from Buffalo Airport to Missouri.

How old do you have to be to fly from Buffalo Airport to Missouri?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Buffalo Airport to Missouri.

What documentation or ID do you need to fly to Missouri?

The travel and health documents required for your trip to Missouri can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Missouri. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$126 Cheap Flights from Buffalo to Missouri in 2026

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Find the cheapest flights from Buffalo to Missouri

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

1:56 pm - 6:50 am

BUF

STL

17h 54m

1 stop

4:59 pm - 12:42 pm

STL

BUF

18h 43m

2 stops

$228Frontier

Tue, Apr 14 - Tue, Apr 21

5:57 pm - 9:08 pm

BUF

STL

4h 11m

1 stop

9:10 am - 5:16 pm

STL

BUF

7h 06m

1 stop

$237United Airlines

Tue, Apr 14 - Wed, Apr 15

8:16 pm - 11:19 pm

BUF

STL

28h 03m

1 stop

4:59 pm - 10:49 am

STL

BUF

16h 50m

1 stop

$246Frontier

Mon, Apr 13 - Fri, Apr 17

4:59 pm - 11:36 pm

BUF

STL

7h 37m

1 stop

6:48 am - 11:39 am

STL

BUF

3h 51m

1 stop

$250Delta

Mon, Apr 13 - Wed, Apr 15

4:00 pm - 10:10 pm

BUF

STL

7h 10m

2 stops

5:35 am - 10:20 am

STL

BUF

3h 45m

1 stop

$252Southwest

Tue, Apr 14 - Wed, Apr 15

6:55 pm - 10:10 pm

BUF

STL

4h 15m

1 stop

10:25 am - 3:20 pm

STL

BUF

3h 55m

1 stop

$257Southwest

Tue, Apr 14 - Tue, Apr 21

11:31 am - 3:58 pm

BUF

COU

5h 27m

1 stop

4:28 pm - 9:36 pm

COU

BUF

4h 08m

1 stop

$258American Airlines

Fri, May 1 - Mon, May 4

6:00 am - 9:46 am

BUF

COU

4h 46m

1 stop

10:16 am - 10:04 pm

COU

BUF

10h 48m

2 stops

$264American Airlines

Fri, May 1 - Mon, May 4

11:37 am - 7:19 pm

BUF

MCI

8h 42m

1 stop

6:30 am - 1:54 pm

MCI

BUF

6h 24m

1 stop

$342Delta

Wed, Apr 8 - Mon, Apr 13

11:12 am - 11:53 pm

BUF

MCI

13h 41m

1 stop

12:24 pm - 12:42 pm

MCI

BUF

23h 18m

2 stops

$370Multiple Airlines

Wed, Apr 8 - Mon, Apr 13

Frontier flights from Buffalo to Missouri

Our best Frontier deals on Buffalo to Missouri flight tickets

Frontier

Apr 14

BUF1:56 pmBuffalo

17h 54m

1 stop

STL6:50 amLambert-St Louis

Apr 21

STL4:59 pmLambert-St Louis

18h 43m

2 stops

BUF12:42 pmBuffalo

$228

Frontier

Apr 13

BUF8:16 pmBuffalo

28h 03m

1 stop

STL11:19 pmLambert-St Louis

Apr 17

STL4:59 pmLambert-St Louis

16h 50m

1 stop

BUF10:49 amBuffalo

$246

Frontier

Apr 13

BUF12:42 pmBuffalo

11h 43m

2 stops

STL11:25 pmLambert-St Louis

Apr 15

STL8:23 pmLambert-St Louis

14h 17m

1 stop

BUF11:40 amBuffalo

$255

Southwest flights from Buffalo to Missouri

Our best Southwest deals on Buffalo to Missouri flight tickets

Southwest

Apr 14

BUF4:00 pmBuffalo

7h 10m

2 stops

STL10:10 pmLambert-St Louis

Apr 15

STL5:35 amLambert-St Louis

3h 45m

1 stop

BUF10:20 amBuffalo

$252

Southwest

Apr 14

BUF6:55 pmBuffalo

4h 15m

1 stop

STL10:10 pmLambert-St Louis

Apr 21

STL10:25 amLambert-St Louis

3h 55m

1 stop

BUF3:20 pmBuffalo

$257

Southwest

Apr 14

BUF9:45 amBuffalo

9h 15m

2 stops

STL6:00 pmLambert-St Louis

Apr 21

STL7:35 amLambert-St Louis

6h 00m

2 stops

BUF2:35 pmBuffalo

$267

Fly from

Fly to

Route

Depart

Return

Price

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Tue 4/14

1:56 pm-6:50 am

1 stop17h 54m

Lambert-St Louis

Tue 4/21

4:59 pm-12:42 pm

2 stops18h 43m

$228

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Tue 4/14

5:57 pm-9:08 pm

1 stop4h 11m

Lambert-St Louis

Wed 4/15

9:10 am-5:16 pm

1 stop7h 06m

$237

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Mon 4/13

8:16 pm-11:19 pm

1 stop28h 03m

Lambert-St Louis

Fri 4/17

4:59 pm-10:49 am

1 stop16h 50m

$246

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Mon 4/13

4:59 pm-11:36 pm

1 stop7h 37m

Lambert-St Louis

Wed 4/15

6:48 am-11:39 am

1 stop3h 51m

$250

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Tue 4/14

4:00 pm-10:10 pm

2 stops7h 10m

Lambert-St Louis

Wed 4/15

5:35 am-10:20 am

1 stop3h 45m

$252

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Tue 4/14

6:55 pm-10:10 pm

1 stop4h 15m

Lambert-St Louis

Tue 4/21

10:25 am-3:20 pm

1 stop3h 55m

$257

BuffaloColumbia

BUF - COU

BUFCOU

Buffalo

Fri 5/1

11:31 am-3:58 pm

1 stop5h 27m

Columbia Regional

Mon 5/4

4:28 pm-9:36 pm

1 stop4h 08m

$258

BuffaloColumbia

BUF - COU

BUFCOU

Buffalo

Fri 5/1

6:00 am-9:46 am

1 stop4h 46m

Columbia Regional

Mon 5/4

10:16 am-10:04 pm

2 stops10h 48m

$264

BuffaloKansas City

BUF - MCI

BUFMCI

Buffalo

Wed 4/8

11:37 am-7:19 pm

1 stop8h 42m

Kansas City

Mon 4/13

6:30 am-1:54 pm

1 stop6h 24m

$342

BuffaloKansas City

BUF - MCI

BUFMCI

Buffalo

Wed 4/8

11:12 am-11:53 pm

1 stop13h 41m

Kansas City

Mon 4/13

12:24 pm-12:42 pm

2 stops23h 18m

$370

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Buffalo to Missouri

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Missouri?

In general, September is the cheapest month to fly from Buffalo to Missouri. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $316. If you aren’t able to travel to Missouri during the month of September, then flying in December is also cheap. Prices for this month can be found on momondo for an average of $319.

Cheap Buffalo to Missouri flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Buffalo to Missouri

Fastest flight time	4h 00m
Direct flights	None

The fastest flight from Buffalo to Missouri takes 4h 00m

There are no direct flights from Buffalo to Missouri. There are no popular flight routes from Buffalo to Missouri.

Search flight deals

When did momondo last update prices for flights from Buffalo Airport to Missouri?
Prices for flights from Buffalo Airport to Missouri are updated daily.
How many operators does momondo search for flights from Buffalo Airport to Missouri?
As of February 2026, there are 4 operators available to choose from for flights from Buffalo Airport to Missouri.
How old do you have to be to fly from Buffalo Airport to Missouri?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Buffalo Airport to Missouri.
What documentation or ID do you need to fly to Missouri?
The travel and health documents required for your trip to Missouri can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Missouri. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Buffalo to Missouri

Compare and see reviews for airlines that fly from Buffalo to Missouri with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $164	Free Cancellation	Rating 7.9 8,244 reviews	Search Delta flights
American Airlines	PriceFrom $197	Free Cancellation	Rating 7.1 11,370 reviews	Search American Airlines flights
Southwest	PriceFrom $236	Free Cancellation	Rating 8.0 4,303 reviews	Search Southwest flights
United Airlines	PriceFrom $294	Free Cancellation	Rating 7.4 9,370 reviews	Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Buffalo to Missouri?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Missouri from Buffalo.

Can I find flights from Buffalo to Missouri with flexible booking policies on momondo?

Flights from Buffalo to Missouri with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Buffalo to Missouri?

Once all potential Buffalo to Missouri flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Buffalo to Missouri right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Buffalo to Missouri now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Missouri and let you know when they change.