What is the cheapest airline that flies from Buffalo to Missouri?

Frontier, Delta, and Southwest are the most popular carriers operating from Buffalo to Missouri

How many flights depart from Buffalo to Missouri on average per week?

As of November 2026, 8 flights take off from Buffalo and land in Missouri each week. The most common flight departure day for this route is Mon, with 25% of weekly flights taking off on this day.

What airlines fly to Missouri?

Delta, American Airlines and Southwest are the top three most popular airlines that fly to Missouri from Buffalo according to our data. Delta is the first choice among our users, with 31% of people opting to fly with this airline when traveling to Missouri. Keep in mind that there are 4 different airlines that fly to Missouri on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Buffalo Airport to Missouri?

Prices for flights from Buffalo Airport to Missouri are updated daily.

How many operators does momondo search for flights from Buffalo Airport to Missouri?

As of November 2026, there are 4 operators available to choose from for flights from Buffalo Airport to Missouri.

How old do you have to be to fly from Buffalo Airport to Missouri?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Buffalo Airport to Missouri.

What documentation or ID do you need to fly to Missouri?

The travel and health documents required for your trip to Missouri can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Missouri. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$125 Cheap Flights from Buffalo to Missouri in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Buffalo to Missouri

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

9:20 pm - 11:59 pmBUF Buffalo-STL Lambert-St Louis

27h 39m1 stop Orlando

1:20 pm - 8:24 pmSTL Lambert-St Louis-BUF Buffalo

6h 04m1 stop Orlando

$285Frontier

Fri, Nov 20 - Mon, Nov 23

9:20 pm - 10:16 amBUF Buffalo-MCI Kansas City

13h 56m1 stop Orlando

11:11 am - 8:24 pmMCI Kansas City-BUF Buffalo

8h 13m1 stop Orlando

$293Frontier

Fri, Nov 20 - Fri, Nov 27

2:50 pm - 7:58 pmBUF Buffalo-MCI Kansas City

6h 08m1 stop Washington, D.C. Dulles Intl

9:47 am - 4:51 pmMCI Kansas City-BUF Buffalo

6h 04m1 stop Chicago O'Hare Intl

$320United Airlines

Fri, Dec 25 - Tue, Jan 5

5:52 pm - 9:14 pmBUF Buffalo-MCI Kansas City

4h 22m1 stop Detroit Metropolitan Wayne County

3:50 pm - 11:55 pmMCI Kansas City-BUF Buffalo

7h 05m1 stop Atlanta Hartsfield-Jackson

$325Delta

Sat, Dec 19 - Wed, Dec 23

5:27 pm - 11:55 pmBUF Buffalo-MCI Kansas City

7h 28m1 stop Atlanta Hartsfield-Jackson

11:40 am - 9:06 pmMCI Kansas City-BUF Buffalo

8h 26m1 stop New York John F Kennedy Intl

$325Delta

Sat, Nov 21 - Fri, Nov 27

5:40 pm - 12:20 amBUF Buffalo-MCI Kansas City

7h 40m1 stop Baltimore/Washington

5:45 am - 2:25 pmMCI Kansas City-BUF Buffalo

7h 40m1 stop Dallas Love Field

$325Southwest

Sat, Dec 19 - Tue, Dec 22

3:55 pm - 10:30 pmBUF Buffalo-MCI Kansas City

7h 35m2 stops Baltimore/Washington Nashville Intl

8:15 am - 3:15 pmMCI Kansas City-BUF Buffalo

6h 00m2 stops Lambert-St Louis Nashville Intl

$335Southwest

Wed, Dec 2 - Wed, Dec 9

6:00 am - 10:45 amBUF Buffalo-COU Columbia Regional

5h 45m1 stop Chicago O'Hare Intl

3:00 pm - 8:36 pmCOU Columbia Regional-BUF Buffalo

4h 36m1 stop Chicago O'Hare Intl

$358United Airlines

Sat, Nov 14 - Wed, Nov 18

6:46 pm - 10:15 pmBUF Buffalo-COU Columbia Regional

4h 29m1 stop Chicago O'Hare Intl

6:15 am - 5:26 pmCOU Columbia Regional-BUF Buffalo

10h 11m2 stops Chicago O'Hare Intl New York LaGuardia

$364American Airlines

Sat, Nov 14 - Wed, Nov 18

10:20 am - 5:52 pmBUF Buffalo-COU Columbia Regional

8h 32m2 stops Boston Logan Intl Chicago O'Hare Intl

6:15 am - 5:26 pmCOU Columbia Regional-BUF Buffalo

10h 11m2 stops Chicago O'Hare Intl New York LaGuardia

$369American Airlines

Sat, Nov 14 - Wed, Nov 18

Cheap last minute flights

Enter your travel dates to find the best prices.

6:00 am - 10:36 amBUF Buffalo-SGF Springfield-Branson

5h 36m1 stop Chicago O'Hare Intl

6:40 pm - 2:47 amSGF Springfield-Branson-BUF Buffalo

7h 07m1 stop Chicago O'Hare Intl

$501United Airlines

Sat, Nov 7 - Sun, Nov 29

3:55 pm - 8:51 pmBUF Buffalo-MCI Kansas City

5h 56m1 stop Detroit Metropolitan Wayne County

11:40 am - 6:40 pmMCI Kansas City-BUF Buffalo

6h 00m1 stop New York John F Kennedy Intl

$583Delta

Tue, Nov 10 - Tue, Nov 17

1:53 pm - 7:43 pmBUF Buffalo-MCI Kansas City

6h 50m1 stop Chicago O'Hare Intl

6:00 am - 2:10 pmMCI Kansas City-BUF Buffalo

7h 10m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

$588United Airlines

Tue, Nov 10 - Tue, Nov 17

3:55 pm - 10:30 pmBUF Buffalo-MCI Kansas City

7h 35m2 stops Baltimore/Washington Nashville Intl

12:20 pm - 8:55 pmMCI Kansas City-BUF Buffalo

7h 35m2 stops Lambert-St Louis Chicago Midway

$593Southwest

Tue, Nov 10 - Tue, Nov 17

6:00 am - 4:21 pmBUF Buffalo-SGF Springfield-Branson

11h 21m2 stops Newark Denver Intl

6:40 pm - 2:47 amSGF Springfield-Branson-BUF Buffalo

7h 07m1 stop Chicago O'Hare Intl

$612United Airlines

Sat, Nov 7 - Sun, Nov 29

4:55 pm - 10:25 pmBUF Buffalo-STL Lambert-St Louis

6h 30m1 stop Denver Intl

3:05 pm - 11:25 pmSTL Lambert-St Louis-BUF Buffalo

7h 20m1 stop Orlando

$697Southwest

Fri, Nov 6 - Sun, Nov 8

6:15 am - 9:49 amBUF Buffalo-STL Lambert-St Louis

4h 34m1 stop Detroit Metropolitan Wayne County

7:39 am - 1:29 pmSTL Lambert-St Louis-BUF Buffalo

4h 50m1 stop New York LaGuardia

$697Delta

Fri, Nov 6 - Sun, Nov 8

11:00 am - 7:10 pmBUF Buffalo-STL Lambert-St Louis

9h 10m2 stops Baltimore/Washington Milwaukee-Mitchell

10:30 am - 3:25 pmSTL Lambert-St Louis-BUF Buffalo

3h 55m1 stop Chicago Midway

$702Southwest

Fri, Nov 6 - Sun, Nov 8

6:00 am - 11:30 amBUF Buffalo-MCI Kansas City

6h 30m1 stop Atlanta Hartsfield-Jackson

6:36 am - 11:18 amMCI Kansas City-BUF Buffalo

3h 42m1 stop Detroit Metropolitan Wayne County

$721Delta

Thu, Nov 5 - Thu, Nov 12

6:00 am - 12:10 pmBUF Buffalo-STL Lambert-St Louis

7h 10m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl

8:00 am - 2:10 pmSTL Lambert-St Louis-BUF Buffalo

5h 10m1 stop Washington, D.C. Dulles Intl

$785United Airlines

Fri, Nov 6 - Sun, Nov 8

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Southwest flights from Buffalo to Missouri

Our best Southwest deals on Buffalo to Missouri flight tickets

Southwest

Dec 2

BUF3:55 pmBuffalo

7h 35m

2 stops

MCI10:30 pmKansas City

Dec 9

MCI8:15 amKansas City

6h 00m

2 stops

BUF3:15 pmBuffalo

$335

Southwest

Dec 3

BUF5:55 amBuffalo

6h 40m

1 stop

MCI11:35 amKansas City

Dec 5

MCI7:45 amKansas City

6h 10m

2 stops

BUF2:55 pmBuffalo

$357

Southwest

Dec 20

BUF6:30 pmBuffalo

7h 40m

1 stop

MCI1:10 amKansas City

Dec 22

MCI5:45 amKansas City

7h 40m

1 stop

BUF2:25 pmBuffalo

$363

Frontier flights from Buffalo to Missouri

Our best Frontier deals on Buffalo to Missouri flight tickets

Frontier

Nov 20

BUF9:20 pmBuffalo

27h 39m

1 stop

STL11:59 pmLambert-St Louis

Nov 23

STL1:20 pmLambert-St Louis

6h 04m

1 stop

BUF8:24 pmBuffalo

$285

Frontier

Nov 20

BUF9:20 pmBuffalo

13h 56m

1 stop

MCI10:16 amKansas City

Nov 27

MCI11:11 amKansas City

8h 13m

1 stop

BUF8:24 pmBuffalo

$293

Frontier

Nov 20

BUF9:20 pmBuffalo

13h 56m

1 stop

MCI10:16 amKansas City

Nov 23

MCI11:11 amKansas City

8h 13m

1 stop

BUF8:24 pmBuffalo

$300

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

BuffaloSt. Louis

BUF Buffalo - STL Lambert-St Louis

BUFSTL

Buffalo

Fri 11/20

9:20 pm-11:59 pm

1 stop27h 39m

Lambert-St Louis

Mon 11/23

1:20 pm-8:24 pm

1 stop6h 04m

$285

BuffaloKansas City

BUF Buffalo - MCI Kansas City

BUFMCI

Buffalo

Fri 11/20

9:20 pm-10:16 am

1 stop13h 56m

Kansas City

Fri 11/27

11:11 am-8:24 pm

1 stop8h 13m

$293

BuffaloKansas City

BUF Buffalo - MCI Kansas City

BUFMCI

Buffalo

Fri 12/25

2:50 pm-7:58 pm

1 stop6h 08m

Kansas City

Tue 1/5

9:47 am-4:51 pm

1 stop6h 04m

$320

BuffaloKansas City

BUF Buffalo - MCI Kansas City

BUFMCI

Buffalo

Sat 12/19

5:52 pm-9:14 pm

1 stop4h 22m

Kansas City

Wed 12/23

3:50 pm-11:55 pm

1 stop7h 05m

$325

BuffaloKansas City

BUF Buffalo - MCI Kansas City

BUFMCI

Buffalo

Sat 11/21

5:27 pm-11:55 pm

1 stop7h 28m

Kansas City

Fri 11/27

11:40 am-9:06 pm

1 stop8h 26m

$325

BuffaloKansas City

BUF Buffalo - MCI Kansas City

BUFMCI

Buffalo

Sat 12/19

5:40 pm-12:20 am

1 stop7h 40m

Kansas City

Tue 12/22

5:45 am-2:25 pm

1 stop7h 40m

$325

BuffaloKansas City

BUF Buffalo - MCI Kansas City

BUFMCI

Buffalo

Wed 12/2

3:55 pm-10:30 pm

2 stops7h 35m

Kansas City

Wed 12/9

8:15 am-3:15 pm

2 stops6h 00m

$335

Quickest round-trip

BuffaloColumbia

BUF Buffalo - COU Columbia Regional

BUFCOU

Buffalo

Sat 11/14

6:00 am-10:45 am

1 stop5h 45m

Columbia Regional

Wed 11/18

3:00 pm-8:36 pm

1 stop4h 36m

$358

BuffaloColumbia

BUF Buffalo - COU Columbia Regional

BUFCOU

Buffalo

Sat 11/14

6:46 pm-10:15 pm

1 stop4h 29m

Columbia Regional

Wed 11/18

6:15 am-5:26 pm

2 stops10h 11m

$364

BuffaloColumbia

BUF Buffalo - COU Columbia Regional

BUFCOU

Buffalo

Sat 11/14

10:20 am-5:52 pm

2 stops8h 32m

Columbia Regional

Wed 11/18

6:15 am-5:26 pm

2 stops10h 11m

$369

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Buffalo to Missouri

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Missouri?

In general, September is the cheapest month to fly from Buffalo to Missouri. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $354. If you aren’t able to travel to Missouri during the month of September, then flying in January is also cheap. Prices for this month can be found on momondo for an average of $357.

Can stopping save me money on Buffalo to Missouri flights?

You could potentially save up to 78% on your flight if you consider stops on a Buffalo to Missouri flight.

Cheap Buffalo to Missouri flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Buffalo to Missouri

Best Price Found	$125
Fastest flight time	4h 28m
Direct flights	None

The best one-way flight to Missouri from Buffalo in the past 72 hours is $125. The best round-trip flight deal from Buffalo to Missouri found on momondo in the last 72 hours is $285.

The fastest flight from Buffalo to Missouri takes 4h 28m

There are no direct flights from Buffalo to Missouri. There are no popular flight routes from Buffalo to Missouri.

Search flight deals

Frequently asked questions about flying from Buffalo to Missouri

When did momondo last update prices for flights from Buffalo Airport to Missouri?
Prices for flights from Buffalo Airport to Missouri are updated daily.
How many operators does momondo search for flights from Buffalo Airport to Missouri?
As of November 2026, there are 4 operators available to choose from for flights from Buffalo Airport to Missouri.
How old do you have to be to fly from Buffalo Airport to Missouri?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Buffalo Airport to Missouri.
What documentation or ID do you need to fly to Missouri?
The travel and health documents required for your trip to Missouri can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Missouri. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Buffalo to Missouri

Compare and see reviews for airlines that fly from Buffalo to Missouri with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $238	Free Cancellation	Rating 7.3 10,461 reviews	Search United Airlines flights
American Airlines	PriceFrom $264	Free Cancellation	Rating 7.0 12,231 reviews	Search American Airlines flights
Delta	PriceFrom $271	Free Cancellation	Rating 7.8 8,698 reviews	Search Delta flights
Southwest	PriceFrom $317	Free Cancellation	Rating 8.0 4,212 reviews	Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Buffalo to Missouri?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Missouri from Buffalo.

Can I find flights from Buffalo to Missouri with flexible booking policies on momondo?

Flights from Buffalo to Missouri with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Buffalo to Missouri?

Once all potential Buffalo to Missouri flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Buffalo to Missouri right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Buffalo to Missouri now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Missouri and let you know when they change.