What is the cheapest airline that flies from Buffalo to Greenville?

Delta, American Airlines, and Southwest are the most popular carriers operating from Buffalo to Greenville

What airlines fly to Greenville?

American Airlines, Delta and Frontier are the top three most popular airlines that fly to Greenville from Buffalo according to our data. American Airlines is the first choice among our users, with 81% of people opting to fly with this airline when traveling to Greenville. Keep in mind that there are 7 different airlines that fly to Greenville on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Buffalo Airport to Greenville Airport?

Prices for flights from Buffalo Airport to Greenville Airport are refreshed on a daily basis.

How many operators does momondo search for flights from Buffalo Airport to Greenville Airport?

As of August 2025, there are 4 operators available to choose from for flights from Buffalo Airport to Greenville Airport.

How old do you have to be to fly from Buffalo Airport to Greenville Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Buffalo Airport to Greenville Airport.

What documentation or ID do you need to fly to Greenville Airport?

The travel and health documents required for your trip to Greenville Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Greenville Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$119 Cheap Flights from Buffalo to Greenville in 2025

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Find the cheapest flights from Buffalo to Greenville

Round-trip

One-way

Last minute

Cheap round-trip flights

5:33 pm - 10:00 pmBUF-GSP

4h 27m1 stop

6:35 am - 1:03 pmGSP-BUF

6h 28m1 stop

$237American Airlines

Find Deal

Tue, Sep 23 - Thu, Oct 2

8:00 am - 12:28 pmBUF-GSP

4h 28m1 stop

6:00 am - 11:00 amGSP-BUF

5h 00m1 stop

$259American Airlines

Find Deal

Thu, Sep 11 - Sun, Sep 14

5:30 am - 10:52 amBUF-GSP

5h 22m1 stop

8:00 am - 1:07 pmGSP-BUF

5h 07m1 stop

$273American Airlines

Find Deal

Thu, Aug 28 - Mon, Sep 1

5:33 pm - 10:58 pmBUF-GSP

5h 25m2 stops

6:00 am - 11:00 amGSP-BUF

5h 00m1 stop

$284American Airlines

Find Deal

Tue, Sep 23 - Thu, Oct 2

6:00 am - 1:03 pmBUF-GSP

7h 03m1 stop

6:20 am - 10:26 amGSP-BUF

4h 06m1 stop

$288American Airlines

Find Deal

Thu, Oct 23 - Mon, Oct 27

3:40 pm - 9:35 pmBUF-GSP

5h 55m1 stop

10:35 am - 8:40 pmGSP-BUF

10h 05m2 stops

$293Southwest

Find Deal

Thu, Nov 13 - Mon, Nov 17

2:50 pm - 10:46 pmBUF-GSP

7h 56m2 stops

6:01 pm - 10:42 pmGSP-BUF

4h 41m1 stop

$312United Airlines

Find Deal

Tue, Sep 23 - Thu, Oct 2

10:15 am - 7:55 pmBUF-GSP

9h 40m2 stops

9:30 am - 3:10 pmGSP-BUF

5h 40m1 stop

$315Southwest

Find Deal

Wed, Sep 17 - Wed, Sep 24

2:50 pm - 10:46 pmBUF-GSP

7h 56m2 stops

9:35 am - 10:42 pmGSP-BUF

13h 07m2 stops

$398United Airlines

Find Deal

Tue, Sep 23 - Thu, Oct 2

6:20 am - 1:09 pmBUF-GSP

6h 49m2 stops

5:30 am - 11:39 amGSP-BUF

6h 09m2 stops

$1,544Delta

Find Deal

Thu, Aug 28 - Mon, Sep 1

Delta flights from Buffalo to Greenville

Our best Delta deals on Buffalo to Greenville flight tickets

Delta

Aug 7

BUF5:56 pmBuffalo

5h 57m

1 stop

GSP11:53 pmGreenville

Aug 9

GSP11:15 amGreenville

3h 57m

1 stop

BUF3:12 pmBuffalo

$596

Find similar

Delta

Aug 28

BUF6:20 amBuffalo

6h 49m

2 stops

GSP1:09 pmGreenville

Sep 1

GSP5:30 amGreenville

6h 09m

2 stops

BUF11:39 amBuffalo

$1,544

Find similar

Southwest flights from Buffalo to Greenville

Our best Southwest deals on Buffalo to Greenville flight tickets

Southwest

Nov 13

BUF3:40 pmBuffalo

5h 55m

1 stop

GSP9:35 pmGreenville

Nov 17

GSP10:35 amGreenville

10h 05m

2 stops

BUF8:40 pmBuffalo

$293

Find similar

Southwest

Sep 17

BUF10:15 amBuffalo

9h 40m

2 stops

GSP7:55 pmGreenville

Sep 24

GSP9:30 amGreenville

5h 40m

1 stop

BUF3:10 pmBuffalo

$315

Find similar

Southwest

Sep 11

BUF10:30 amBuffalo

7h 35m

2 stops

GSP6:05 pmGreenville

Sep 13

GSP8:20 amGreenville

4h 05m

1 stop

BUF12:25 pmBuffalo

$319

Find similar

Fly from

Fly to

Route

Depart

Return

Price

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Tue 9/23

5:33 pm-10:00 pm

1 stop4h 27m

Greenville

Thu 10/2

6:35 am-1:03 pm

1 stop6h 28m

$237

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Thu 9/11

8:00 am-12:28 pm

1 stop4h 28m

Greenville

Sun 9/14

6:00 am-11:00 am

1 stop5h 00m

$259

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Thu 8/28

5:30 am-10:52 am

1 stop5h 22m

Greenville

Mon 9/1

8:00 am-1:07 pm

1 stop5h 07m

$273

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Tue 9/23

5:33 pm-10:58 pm

2 stops5h 25m

Greenville

Thu 10/2

6:00 am-11:00 am

1 stop5h 00m

$284

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Thu 10/23

6:00 am-1:03 pm

1 stop7h 03m

Greenville

Mon 10/27

6:20 am-10:26 am

1 stop4h 06m

$288

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Thu 11/13

3:40 pm-9:35 pm

1 stop5h 55m

Greenville

Mon 11/17

10:35 am-8:40 pm

2 stops10h 05m

$293

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Tue 9/23

2:50 pm-10:46 pm

2 stops7h 56m

Greenville

Thu 10/2

6:01 pm-10:42 pm

1 stop4h 41m

$312

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Wed 9/17

10:15 am-7:55 pm

2 stops9h 40m

Greenville

Wed 9/24

9:30 am-3:10 pm

1 stop5h 40m

$315

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Tue 9/23

2:50 pm-10:46 pm

2 stops7h 56m

Greenville

Thu 10/2

9:35 am-10:42 pm

2 stops13h 07m

$398

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Thu 8/28

6:20 am-1:09 pm

2 stops6h 49m

Greenville

Mon 9/1

5:30 am-11:39 am

2 stops6h 09m

$1,544

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Buffalo to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Greenville?

The month of June is another great option to travel to Greenville, with average flight prices from Buffalo averaging around $311.

What is the cheapest day to depart on your flight to Greenville?

According to our data, Saturday is the cheapest day to fly to Greenville from Buffalo. The lowest ticket price found for a Saturday departure recently was $365. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $539. These prices are subject to change though, so be sure to set up a Price Alert for flights to Greenville.

What is the cheapest time of day to depart on your flight to Greenville?

Our most recent data shows that the best time of day to fly to Greenville is in the evening. Flights from Buffalo to Greenville during this time can be as low as $282. Flights to Greenville are more costly in the morning, with an average ticket price of $396. Departure times in the morning fall within the peak daily travel times, which is why tickets can be more expensive.

How have Buffalo to Greenville flight prices changed over time?

When to book flights from Buffalo to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from Buffalo to Greenville according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Buffalo to Greenville (BUF to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Buffalo to Greenville

Best Price Found	$119
Fastest flight time	3h 49m
Direct flights	None
Airports in Greenville	1 airport

The best one-way flight to Greenville from Buffalo in the past 72 hours is $119. The best round-trip flight deal from Buffalo to Greenville found on momondo in the last 72 hours is $237.

The fastest flight from Buffalo to Greenville takes 3h 49m

There are no direct flights from Buffalo to Greenville. Popular non-direct route for this connection is Buffalo Airport - Greenville Airport.

There is 1 airport near Greenville: Greenville (GSP)

Search flight deals

How far is Buffalo to Greenville by plane?
A flight from Buffalo to Greenville will travel around 585.9 mi. A reasonable flight in good conditions will take 3h 49m.
When did momondo last update prices for flights from Buffalo Airport to Greenville Airport?
Prices for flights from Buffalo Airport to Greenville Airport are refreshed on a daily basis.
How many operators does momondo search for flights from Buffalo Airport to Greenville Airport?
As of August 2025, there are 4 operators available to choose from for flights from Buffalo Airport to Greenville Airport.
How old do you have to be to fly from Buffalo Airport to Greenville Airport?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Buffalo Airport to Greenville Airport.
What documentation or ID do you need to fly to Greenville Airport?
The travel and health documents required for your trip to Greenville Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Greenville Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular airline from Buffalo to Greenville?
momondo data reveals that the most frequently booked airline on the route from Buffalo to Greenville is American Airlines, representing 58% of all bookings. The subsequent popular airlines are Southwest at 16%, Delta at 13%, and United Airlines at 12%.

Best airlines flying from Buffalo to Greenville

Compare and see reviews for airlines that fly from Buffalo to Greenville with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $198	Free Cancellation	Rating 7.2 10,000 reviews	Search American Airlines flights
Delta	PriceFrom $216	Free Cancellation	Rating 8.0 7,987 reviews	Search Delta flights
Southwest	PriceFrom $218	Free Cancellation	Rating 8.0 4,246 reviews	Search Southwest flights
United Airlines	PriceFrom $278	Free Cancellation	Rating 7.4 8,912 reviews	Search United Airlines flights

Anderson

Simpsonville

Greenwood

Seneca

Greer

Duncan

Why use momondo?

Why should I use momondo to find a flight deal from Buffalo to Greenville?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Buffalo to Greenville. momondo saves you time and could save you money on your trip.

Can I find flights from Buffalo to Greenville with flexible booking policies on momondo?

momondo does allow users to show only those flights to Greenville from Buffalo which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Buffalo to Greenville?

Once all potential Buffalo to Greenville flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Buffalo to Greenville right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Buffalo to Greenville now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Greenville and let you know when they change.