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Cheap flights from Buffalo to Greenville from $136

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Buffalo to Greenville departing on 4/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Buffalo to Greenville

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:59 pm - 11:02 pm
BUF
-
GSP
4h 03m
1 stop
American Airlines Logo
6:00 am - 11:14 am
GSP
-
BUF
5h 14m
1 stop
$287American Airlines
Tue, Apr 7 - Thu, Apr 9
American Airlines Logo
11:29 am - 10:22 pm
BUF
-
GSP
10h 53m
1 stop
American Airlines Logo
6:00 am - 10:58 am
GSP
-
BUF
4h 58m
1 stop
$308American Airlines
Tue, Mar 24 - Wed, Apr 1
American Airlines Logo
5:29 pm - 11:12 pm
BUF
-
GSP
5h 43m
2 stops
American Airlines Logo
7:07 am - 12:14 pm
GSP
-
BUF
5h 07m
1 stop
$324American Airlines
Tue, Mar 24 - Wed, Apr 1
American Airlines Logo
7:23 am - 12:14 pm
BUF
-
GSP
4h 51m
1 stop
American Airlines Logo
12:35 pm - 4:42 pm
GSP
-
BUF
4h 07m
1 stop
$333American Airlines
Thu, Apr 2 - Wed, Apr 8
American Airlines Logo
7:23 am - 12:14 pm
BUF
-
GSP
4h 51m
1 stop
American Airlines Logo
12:35 pm - 4:42 pm
GSP
-
BUF
4h 07m
1 stop
$335American Airlines
Thu, Apr 2 - Wed, Apr 8
American Airlines Logo
7:23 am - 12:14 pm
BUF
-
GSP
4h 51m
1 stop
American Airlines Logo
6:00 am - 11:14 am
GSP
-
BUF
5h 14m
1 stop
$337American Airlines
Thu, Apr 2 - Wed, Apr 8
American Airlines Logo
7:23 am - 12:14 pm
BUF
-
GSP
4h 51m
1 stop
American Airlines Logo
5:20 am - 11:58 am
GSP
-
BUF
6h 38m
2 stops
$338American Airlines
Thu, Apr 2 - Wed, Apr 8
American Airlines Logo
7:23 am - 12:14 pm
BUF
-
GSP
4h 51m
1 stop
American Airlines Logo
5:20 am - 11:58 am
GSP
-
BUF
6h 38m
2 stops
$340American Airlines
Thu, Apr 2 - Wed, Apr 8
American Airlines Logo
7:23 am - 12:14 pm
BUF
-
GSP
4h 51m
1 stop
American Airlines Logo
5:20 am - 11:58 am
GSP
-
BUF
6h 38m
2 stops
$342American Airlines
Thu, Apr 2 - Wed, Apr 8
American Airlines Logo
11:28 am - 10:08 pm
BUF
-
GSP
10h 40m
1 stop
American Airlines Logo
6:00 am - 10:58 am
GSP
-
BUF
4h 58m
1 stop
$356American Airlines
Thu, Mar 5 - Sat, Mar 7

United Airlines flights from Buffalo to Greenville

Our best United Airlines deals on Buffalo to Greenville flight tickets
United Airlines
Feb 21
BUF10:00 amBuffalo
10h 41m
2 stops
GSP8:41 pmGreenville
Feb 25
GSP12:05 pmGreenville
7h 01m
2 stops
BUF7:06 pmBuffalo
$458
United Airlines
Feb 20
BUF6:25 pmBuffalo
5h 34m
1 stop
GSP11:59 pmGreenville
Feb 24
GSP6:30 amGreenville
6h 42m
1 stop
BUF1:12 pmBuffalo
$517
United Airlines
Feb 20
BUF6:25 pmBuffalo
5h 34m
1 stop
GSP11:59 pmGreenville
Feb 24
GSP12:05 pmGreenville
7h 01m
2 stops
BUF7:06 pmBuffalo
$522

American Airlines flights from Buffalo to Greenville

Our best American Airlines deals on Buffalo to Greenville flight tickets
American Airlines
Apr 7
BUF6:59 pmBuffalo
4h 03m
1 stop
GSP11:02 pmGreenville
Apr 9
GSP6:00 amGreenville
5h 14m
1 stop
BUF11:14 amBuffalo
$287
American Airlines
Mar 24
BUF11:29 amBuffalo
10h 53m
1 stop
GSP10:22 pmGreenville
Apr 1
GSP6:00 amGreenville
4h 58m
1 stop
BUF10:58 amBuffalo
$308
American Airlines
Mar 24
BUF5:29 pmBuffalo
5h 43m
2 stops
GSP11:12 pmGreenville
Apr 1
GSP7:07 amGreenville
5h 07m
1 stop
BUF12:14 pmBuffalo
$324

momondo Fare Finder

 
Customize your flight search to find flights from Buffalo to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 6, 2026.
Use the filters below to find and compare flights from Buffalo to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Tue 4/7

6:59 pm-11:02 pm

1 stop4h 03m

Greenville

Thu 4/9

6:00 am-11:14 am

1 stop5h 14m

$287

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Tue 3/24

11:29 am-10:22 pm

1 stop10h 53m

Greenville

Wed 4/1

6:00 am-10:58 am

1 stop4h 58m

$308

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Tue 3/24

5:29 pm-11:12 pm

2 stops5h 43m

Greenville

Wed 4/1

7:07 am-12:14 pm

1 stop5h 07m

$324

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Thu 4/2

7:23 am-12:14 pm

1 stop4h 51m

Greenville

Wed 4/8

12:35 pm-4:42 pm

1 stop4h 07m

$333

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Thu 4/2

7:23 am-12:14 pm

1 stop4h 51m

Greenville

Wed 4/8

12:35 pm-4:42 pm

1 stop4h 07m

$335

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Thu 4/2

7:23 am-12:14 pm

1 stop4h 51m

Greenville

Wed 4/8

6:00 am-11:14 am

1 stop5h 14m

$337

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Thu 4/2

7:23 am-12:14 pm

1 stop4h 51m

Greenville

Wed 4/8

5:20 am-11:58 am

2 stops6h 38m

$338

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Thu 4/2

7:23 am-12:14 pm

1 stop4h 51m

Greenville

Wed 4/8

5:20 am-11:58 am

2 stops6h 38m

$340

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Thu 4/2

7:23 am-12:14 pm

1 stop4h 51m

Greenville

Wed 4/8

5:20 am-11:58 am

2 stops6h 38m

$342

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Thu 3/5

11:28 am-10:08 pm

1 stop10h 40m

Greenville

Sat 3/7

6:00 am-10:58 am

1 stop4h 58m

$356

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Greenville from

How to get the cheapest flight ticket from Buffalo to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Greenville?

The month of March is another great option to travel to Greenville, with average flight prices from Buffalo averaging around $321.

How have Buffalo to Greenville flight prices changed over time?

When to book flights from Buffalo to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from Buffalo to Greenville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Buffalo to Greenville (BUF to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Buffalo to Greenville

Fastest flight time

3h 45m

Direct flights

None
The fastest flight from Buffalo to Greenville takes 3h 45m
There are no direct flights from Buffalo to Greenville. There are no popular flight routes from Buffalo to Greenville.
Search flight deals

  • How far is Buffalo to Greenville by plane?

    A flight from Buffalo to Greenville will travel around 585.9 mi. A reasonable flight in good conditions will take 3h 45m.

  • When did momondo last update prices for flights from Buffalo Airport to Greenville Airport?

    Prices for flights from Buffalo Airport to Greenville Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Buffalo Airport to Greenville Airport?

  • How old do you have to be to fly from Buffalo Airport to Greenville Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Buffalo Airport to Greenville Airport.

  • What documentation or ID do you need to fly to Greenville Airport?

    The travel and health documents required for your trip to Greenville Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Greenville Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Buffalo to Greenville?

Best airlines flying from Buffalo to Greenville

Compare and see reviews for airlines that fly from Buffalo to Greenville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $198Free CancellationRating
7.2
11,248 reviews
Search American Airlines flights
DeltaPriceFrom $236Free CancellationRating
7.9
8,162 reviews
Search Delta flights
SouthwestPriceFrom $277Free CancellationRating
8.0
4,280 reviews
Search Southwest flights

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Anderson
Simpsonville
Greenwood
Seneca
Greer
Duncan

Why use momondo?

Why should I use momondo to find a flight deal from Buffalo to Greenville?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Buffalo to Greenville. momondo saves you time and could save you money on your trip.

Can I find flights from Buffalo to Greenville with flexible booking policies on momondo?

momondo does allow users to show only those flights to Greenville from Buffalo which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Buffalo to Greenville?

Once all potential Buffalo to Greenville flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Buffalo to Greenville right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Buffalo to Greenville now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Greenville and let you know when they change.

An easier way to manage your Greenville trip

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