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Cheap flights from Buffalo to Greenville from $147

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Buffalo to Greenville departing on 8/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Buffalo to Greenville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
7:39 pm - 11:43 pm
BUF
-
GSP
4h 04m
1 stop
Delta Logo
7:51 pm - 11:59 pm
GSP
-
BUF
4h 08m
1 stop
$321Delta
Mon, Jun 1 - Mon, Jun 8
American Airlines Logo
4:49 pm - 11:52 pm
BUF
-
GSP
7h 03m
2 stops
American Airlines Logo
6:31 pm - 11:54 pm
GSP
-
BUF
5h 23m
1 stop
$326American Airlines
Sat, Jun 20 - Mon, Jun 22
Multiple Airlines Logo
11:35 am - 9:46 am
BUF
-
GSP
22h 11m
2 stops
Multiple Airlines Logo
8:28 pm - 7:12 pm
GSP
-
BUF
22h 44m
1 stop
$328Multiple Airlines
Thu, Jun 18 - Mon, Jun 22
Delta Logo
5:12 pm - 11:59 pm
BUF
-
GSP
6h 47m
1 stop
Delta Logo
7:10 am - 11:22 am
GSP
-
BUF
4h 12m
1 stop
$337Delta
Thu, Jul 2 - Wed, Jul 8
American Airlines Logo
7:31 pm - 11:52 pm
BUF
-
GSP
4h 21m
1 stop
American Airlines Logo
7:14 pm - 11:56 pm
GSP
-
BUF
4h 42m
1 stop
$339American Airlines
Mon, Jun 1 - Sun, Jun 7
Delta Logo
5:12 pm - 9:31 pm
BUF
-
GSP
4h 19m
1 stop
Delta Logo
7:10 am - 11:22 am
GSP
-
BUF
4h 12m
1 stop
$354Delta
Thu, Jul 30 - Sun, Aug 2
Delta Logo
6:00 am - 10:40 am
BUF
-
GSP
4h 40m
1 stop
Delta Logo
7:10 am - 11:19 am
GSP
-
BUF
4h 09m
1 stop
$359Delta
Mon, Aug 3 - Sun, Aug 9
Delta Logo
7:39 pm - 11:43 pm
BUF
-
GSP
4h 04m
1 stop
Delta Logo
7:51 pm - 11:59 pm
GSP
-
BUF
4h 08m
1 stop
$364Delta
Mon, Jun 1 - Sun, Jun 7
United Airlines Logo
7:00 pm - 11:34 pm
BUF
-
GSP
4h 34m
1 stop
United Airlines Logo
7:40 pm - 11:59 pm
GSP
-
BUF
4h 19m
1 stop
$367United Airlines
Wed, Jul 1 - Wed, Jul 8
Southwest Logo
4:00 pm - 10:35 pm
BUF
-
GSP
6h 35m
2 stops
Southwest Logo
7:55 am - 2:25 pm
GSP
-
BUF
6h 30m
1 stop
$371Southwest
Mon, Jun 1 - Sun, Jun 7

American Airlines flights from Buffalo to Greenville

Our best American Airlines deals on Buffalo to Greenville flight tickets
American Airlines
Jun 20
BUF4:49 pmBuffalo
7h 03m
2 stops
GSP11:52 pmGreenville
Jun 22
GSP6:31 pmGreenville
5h 23m
1 stop
BUF11:54 pmBuffalo
$326
American Airlines
Jun 1
BUF7:31 pmBuffalo
4h 21m
1 stop
GSP11:52 pmGreenville
Jun 7
GSP7:14 pmGreenville
4h 42m
1 stop
BUF11:56 pmBuffalo
$339
American Airlines
May 30
BUF6:05 amBuffalo
4h 03m
1 stop
GSP10:08 amGreenville
Jun 2
GSP6:14 amGreenville
4h 19m
1 stop
BUF10:33 amBuffalo
$377

Delta flights from Buffalo to Greenville

Our best Delta deals on Buffalo to Greenville flight tickets
Delta
Jun 1
BUF7:39 pmBuffalo
4h 04m
1 stop
GSP11:43 pmGreenville
Jun 8
GSP7:51 pmGreenville
4h 08m
1 stop
BUF11:59 pmBuffalo
$321
Delta
Jul 2
BUF5:12 pmBuffalo
6h 47m
1 stop
GSP11:59 pmGreenville
Jul 8
GSP7:10 amGreenville
4h 12m
1 stop
BUF11:22 amBuffalo
$337
Delta
Jul 30
BUF5:12 pmBuffalo
4h 19m
1 stop
GSP9:31 pmGreenville
Aug 2
GSP7:10 amGreenville
4h 12m
1 stop
BUF11:22 amBuffalo
$354

momondo Fare Finder

 
Customize your flight search to find flights from Buffalo to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 13, 2026.
Use the filters below to find and compare flights from Buffalo to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Mon 6/1

7:39 pm-11:43 pm

1 stop4h 04m

Greenville

Mon 6/8

7:51 pm-11:59 pm

1 stop4h 08m

$321

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Sat 6/20

4:49 pm-11:52 pm

2 stops7h 03m

Greenville

Mon 6/22

6:31 pm-11:54 pm

1 stop5h 23m

$326

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Thu 6/18

11:35 am-9:46 am

2 stops22h 11m

Greenville

Mon 6/22

8:28 pm-7:12 pm

1 stop22h 44m

$328

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Thu 7/2

5:12 pm-11:59 pm

1 stop6h 47m

Greenville

Wed 7/8

7:10 am-11:22 am

1 stop4h 12m

$337

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Mon 6/1

7:31 pm-11:52 pm

1 stop4h 21m

Greenville

Sun 6/7

7:14 pm-11:56 pm

1 stop4h 42m

$339

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Thu 7/30

5:12 pm-9:31 pm

1 stop4h 19m

Greenville

Sun 8/2

7:10 am-11:22 am

1 stop4h 12m

$354

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Mon 8/3

6:00 am-10:40 am

1 stop4h 40m

Greenville

Sun 8/9

7:10 am-11:19 am

1 stop4h 09m

$359

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Mon 6/1

7:39 pm-11:43 pm

1 stop4h 04m

Greenville

Sun 6/7

7:51 pm-11:59 pm

1 stop4h 08m

$364

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Wed 7/1

7:00 pm-11:34 pm

1 stop4h 34m

Greenville

Wed 7/8

7:40 pm-11:59 pm

1 stop4h 19m

$367

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Mon 6/1

4:00 pm-10:35 pm

2 stops6h 35m

Greenville

Sun 6/7

7:55 am-2:25 pm

1 stop6h 30m

$371

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Greenville from

How to get the cheapest flight ticket from Buffalo to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Buffalo and Greenville?

What is the cheapest month to fly to Greenville?

The month of August is another great option to travel to Greenville, with average flight prices from Buffalo averaging around $329.

How have Buffalo to Greenville flight prices changed over time?

When to book flights from Buffalo to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from Buffalo to Greenville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Buffalo to Greenville (BUF to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Buffalo to Greenville

Fastest flight time

3h 40m

Direct flights

None
The fastest flight from Buffalo to Greenville takes 3h 40m
There are no direct flights from Buffalo to Greenville. There are no popular flight routes from Buffalo to Greenville.
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Frequently asked questions about flying from Buffalo to Greenville

  • How far is Buffalo to Greenville by plane?

    A flight from Buffalo to Greenville will travel around 585.9 mi. A reasonable flight in good conditions will take 3h 40m.

  • When did momondo last update prices for flights from Buffalo Airport to Greenville Airport?

    Prices for flights from Buffalo Airport to Greenville Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Buffalo Airport to Greenville Airport?

  • How old do you have to be to fly from Buffalo Airport to Greenville Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Buffalo Airport to Greenville Airport.

  • What documentation or ID do you need to fly to Greenville Airport?

    The travel and health documents required for your trip to Greenville Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Greenville Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Buffalo to Greenville?

Best airlines flying from Buffalo to Greenville

Compare and see reviews for airlines that fly from Buffalo to Greenville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $257Free CancellationRating
7.1
11,662 reviews
Search American Airlines flights
SouthwestPriceFrom $294Free CancellationRating
7.9
4,296 reviews
Search Southwest flights
DeltaPriceFrom $298Free CancellationRating
7.9
8,450 reviews
Search Delta flights

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Anderson
Simpsonville
Greenwood
Greer
Seneca
Duncan

Why use momondo?

Why should I use momondo to find a flight deal from Buffalo to Greenville?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Buffalo to Greenville. momondo saves you time and could save you money on your trip.

Can I find flights from Buffalo to Greenville with flexible booking policies on momondo?

momondo does allow users to show only those flights to Greenville from Buffalo which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Buffalo to Greenville?

Once all potential Buffalo to Greenville flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Buffalo to Greenville right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Buffalo to Greenville now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Greenville and let you know when they change.

An easier way to manage your Greenville trip

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