What airlines fly to Florence, South Carolina?

American Airlines, Breeze Airways and Southwest are the top three most popular airlines that fly to Florence, South Carolina from Buffalo according to our data. American Airlines is the first choice among our users, with 66% of people opting to fly with this airline when traveling to Florence, South Carolina. Keep in mind that there are 9 different airlines that fly to Florence, South Carolina on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Buffalo Airport to Florence Airport?

Prices for flights from Buffalo Airport to Florence Airport were last updated today.

How old do you have to be to fly from Buffalo Airport to Florence Airport?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Buffalo Airport to Florence Airport.

What documentation or ID do you need to fly to Florence Airport?

The travel and health documents you'll need for your trip to Florence Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Florence Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$326 Cheap Flights from Buffalo to Florence in 2025/26

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Find the cheapest flights from Buffalo to Florence

Round-trip

One-way

Cheap round-trip flights

8:00 pm - 11:38 pmBUF-FLO

3h 38m1 stop

2:30 pm - 5:58 pmFLO-BUF

3h 28m1 stop

$503American Airlines

Find Deal

Wed, Mar 25 - Sat, Mar 28

5:35 am - 2:05 pmBUF-FLO

8h 30m2 stops

11:09 am - 5:58 pmFLO-BUF

6h 49m1 stop

$508American Airlines

Find Deal

Wed, Mar 25 - Sat, Mar 28

4:20 pm - 11:38 pmBUF-FLO

7h 18m2 stops

5:13 am - 3:00 pmFLO-BUF

9h 47m2 stops

$513American Airlines

Find Deal

Wed, Mar 25 - Sat, Mar 28

American Airlines flights from Buffalo to Florence, South Carolina

Our best American Airlines deals on Buffalo to Florence, South Carolina flight tickets

American Airlines

Mar 25

BUF8:00 pmBuffalo

3h 38m

1 stop

FLO11:38 pmFlorence

Mar 28

FLO2:30 pmFlorence

3h 28m

1 stop

BUF5:58 pmBuffalo

$503

Find similar

American Airlines

Mar 25

BUF5:35 amBuffalo

8h 30m

2 stops

FLO2:05 pmFlorence

Mar 28

FLO11:09 amFlorence

6h 49m

1 stop

BUF5:58 pmBuffalo

$508

Find similar

American Airlines

Mar 25

BUF4:20 pmBuffalo

7h 18m

2 stops

FLO11:38 pmFlorence

Mar 28

FLO5:13 amFlorence

9h 47m

2 stops

BUF3:00 pmBuffalo

$513

Find similar

momondo Fare Finder

Use the filters below to find and compare flights from Buffalo to Florence, South Carolina that are best for you.

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Route

Depart

Return

Price

BuffaloFlorence

BUF - FLO

BUFFLO

Buffalo

Wed 3/25

8:00 pm-11:38 pm

1 stop3h 38m

Florence

Sat 3/28

2:30 pm-5:58 pm

1 stop3h 28m

$503

BuffaloFlorence

BUF - FLO

BUFFLO

Buffalo

Wed 3/25

5:35 am-2:05 pm

2 stops8h 30m

Florence

Sat 3/28

11:09 am-5:58 pm

1 stop6h 49m

$508

BuffaloFlorence

BUF - FLO

BUFFLO

Buffalo

Wed 3/25

4:20 pm-11:38 pm

2 stops7h 18m

Florence

Sat 3/28

5:13 am-3:00 pm

2 stops9h 47m

$513

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

How to get the cheapest flight ticket from Buffalo to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest day to depart on your flight to Florence, South Carolina?

On average, the least expensive day to fly to Florence, South Carolina from Buffalo is on a Wednesday. momondo users have found tickets for Wednesday departures for as low as $373. However, this price may fluctuate depending on the airline, the season, and holidays. On the other hand, Monday is the most expensive day to depart from Buffalo because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $599.

What is the cheapest time of day to depart on your flight to Florence, South Carolina?

According to our data, the cheapest time of day to fly to Florence, South Carolina is in the afternoon. momondo users have found flights departing from Buffalo to Florence, South Carolina in the afternoon for as low as $437. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. In the morning is when there is more demand to fly to Florence, South Carolina, so prices are often more expensive at around $560 per ticket.

When to book flights from Buffalo to Florence, South Carolina

Are you open to changing your travel dates? Check out the ideal times to fly from Buffalo to Florence, South Carolina according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Buffalo to Florence, South Carolina (BUF to FLO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Buffalo to Florence, South Carolina

Direct flights	None

There are no direct flights from Buffalo to Florence, South Carolina. There are no popular flight routes from Buffalo to Florence, South Carolina.

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How far is Buffalo to Florence by plane?
Buffalo and Florence are 602.0 mi apart from one another. Flights usually cover this in 3h 38m, depending on flying conditions and air traffic around both airports.
When did momondo last update prices for flights from Buffalo Airport to Florence Airport?
Prices for flights from Buffalo Airport to Florence Airport were last updated today.
How old do you have to be to fly from Buffalo Airport to Florence Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Buffalo Airport to Florence Airport.
What documentation or ID do you need to fly to Florence Airport?
The travel and health documents you'll need for your trip to Florence Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Florence Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Sumter

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Hartsville

Bennettsville

Darlington

Why use momondo?

Why should I use momondo to find a flight deal from Buffalo to Florence?

It is quick and easy to find Buffalo to Florence flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Florence that suits you.

Can I find flights from Buffalo to Florence with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Florence from Buffalo with this policy.

How can momondo help me find flights from Buffalo to Florence?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Florence from Buffalo.

I’m not ready to book a flight from Buffalo to Florence right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Buffalo to Florence now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Florence and let you know when they change.