Cheap flights from Santa Ana, California from $45

Our data suggests that currently, the cheapest flights from Santa Ana, California are being offered by Delta, Alaska Airlines, and American Airlines. For example, Delta flights from Santa Ana, California to Las Vegas, start at $46, Alaska Airlines flights from Santa Ana, California to San Jose, California cost around $46, and American Airlines flights from Santa Ana, California to Seattle are around $54.

Currently, the cheapest flight from Santa Ana, California found by our users is for $43 to Phoenix-Mesa Gateway Airport. Prices will vary according to several factors such as the departure date and time, but on average you can expect to pay around $74 to travel from Santa Ana, California to Phoenix-Mesa Gateway Airport.

San Francisco, Dallas/Fort Worth Airport and Chicago are currently the destinations served most frequently from Santa Ana, California, with 37, 27 and 21 flights per day on average, respectively.

Airlines including American Airlines, United Airlines and Alaska Airlines frequently fly from Santa Ana, California. You can view other airlines by performing a quick search in the form above.

If you are looking for a cheap first class flight, consider flights to San Francisco, for which the starting price of a first class seat can be as low as $437.

Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport were last updated today.

As of September 2026, there are 23 operators available to choose from for flights from Santa Ana J. Wayne/Orange Cnty Airport.

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santa Ana J. Wayne/Orange Cnty Airport.

The necessary travel and health documents for your Santa Ana J. Wayne/Orange Cnty Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.