Cheap flights from Knoxville from $49

Our data suggests that currently, the cheapest flights from Knoxville are being offered by American Airlines, Delta, and Allegiant Air. For example, American Airlines flights from Knoxville to South Bend, start at $31, Delta flights from Knoxville to Washington, D.C. Dulles Intl Airport cost around $43, and Allegiant Air flights from Knoxville to Gulf Shores are around $72.

Currently, the cheapest flight from Knoxville found by our users is for $35 to Jacksonville. Prices will vary according to several factors such as the departure date and time, but on average you can expect to pay around $93 to travel from Knoxville to Jacksonville.

Atlanta, Chicago and Chicago O'Hare Intl Airport are currently the destinations served most frequently from Knoxville, with 38, 29 and 29 flights per day on average, respectively.

Airlines including American Airlines, Delta and United Airlines frequently fly from Knoxville. You can view other airlines by performing a quick search in the form above.

If you are looking for a cheap first class flight, consider flights to Washington, D.C. Reagan-National Airport, for which the starting price of a first class seat can be as low as $485.

Prices for flights from Knoxville McGhee Tyson Airport are refreshed on a daily basis.

As of September 2025, there are 26 operators available to choose from for flights from Knoxville McGhee Tyson Airport.

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport.

The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.