Cheap flights from Knoxville (TYS) from $55

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Fly to

Route

Depart

Return

Price

Cheapest one-way

KnoxvilleWashington, D.C.

TYS - IAD

TYSIAD

Knoxville McGhee Tyson

Fri 7/10

12:53 pm-2:26 pm

Nonstop1h 33m

$35

KnoxvilleWashington, D.C.

TYS - IAD

TYSIAD

Knoxville McGhee Tyson

Mon 7/27

12:53 pm-2:26 pm

Nonstop1h 33m

$37

Quickest one-way

KnoxvilleWashington, D.C.

TYS - IAD

TYSIAD

Knoxville McGhee Tyson

Mon 6/29

12:49 pm-2:16 pm

Nonstop1h 27m

$38

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Wed 7/22

6:00 am-8:12 am

Nonstop2h 12m

$116

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Tue 7/14

6:00 am-8:12 am

Nonstop2h 12m

$117

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Tue 8/11

4:38 pm-9:34 pm

1 stop4h 56m

$126

KnoxvilleNew York

TYS - LGA

TYSLGA

Knoxville McGhee Tyson

Wed 8/12

1:55 pm-10:30 pm

1 stop8h 35m

$140

KnoxvilleNew York

TYS - LGA

TYSLGA

Knoxville McGhee Tyson

Wed 7/8

12:45 pm-11:00 pm

2 stops10h 15m

$145

KnoxvilleSeattle

TYS - SEA

TYSSEA

Knoxville McGhee Tyson

Tue 9/8

6:20 pm-11:55 pm

1 stop8h 35m

$178

KnoxvilleSeattle

TYS - SEA

TYSSEA

Knoxville McGhee Tyson

Sat 8/15

2:21 pm-9:36 pm

1 stop10h 15m

$199

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

Where can I directly fly to from Knoxville?

Currently, 14 destinations can be reached directly via flights from Knoxville.

Flights from Knoxville to

Atlanta

from$140

Flights from Knoxville to

Austin

from$43

Flights from Knoxville to

Baltimore

from$106

Flights from Knoxville to

Boston

from$71

Flights from Knoxville to

Denver

from$106

Flights from Knoxville to

Fort Lauderdale

from$74

Flights from Knoxville to

Jacksonville

from$47

Flights from Knoxville to

Key West

from$61

Flights from Knoxville to

Las Vegas

from$106

Flights from Knoxville to

Philadelphia

from$44

Flights from Knoxville to

Punta Gorda

from$115

Flights from Knoxville to

Sarasota

from$59

Flights from Knoxville to

Tampa

from$62

Flights from Knoxville to

Valparaiso, Florida

from$59

Find the cheapest flights from Knoxville

One-way

Last minute

International

Domestic

Cheap one-way flights from Knoxville

Enter your travel dates to find the best prices.

12:53 pm - 2:26 pm

TYS

IAD

1h 33mnonstop

$35Allegiant Air

Fri, Jul 10

12:53 pm - 2:26 pm

TYS

IAD

1h 33mnonstop

$37Allegiant Air

Mon, Jul 27

12:49 pm - 2:16 pm

TYS

IAD

1h 27mnonstop

$38Allegiant Air

Mon, Jun 29

6:00 am - 8:12 am

TYS

MIA

2h 12mnonstop

$116American Airlines

Wed, Jul 22

6:00 am - 8:12 am

TYS

MIA

2h 12mnonstop

$117American Airlines

Tue, Jul 14

4:38 pm - 9:34 pm

TYS

MIA

4h 56m

1 stop

$126Delta

Tue, Aug 11

1:55 pm - 10:30 pm

TYS

LGA

8h 35m

1 stop

$140Southwest

Wed, Aug 12

12:45 pm - 11:00 pm

TYS

LGA

10h 15m

2 stops

$145Southwest

Wed, Jul 8

6:20 pm - 11:55 pm

TYS

SEA

8h 35m

1 stop

$178Delta

Tue, Sep 8

2:21 pm - 9:36 pm

TYS

SEA

10h 15m

1 stop

$199United Airlines

Sat, Aug 15

Flights from Knoxville - Travel Insights & Trends

Get data-powered insights and trends into flights from Knoxville to help you craft the best travel plan.

Prices

Other information

What are the most popular domestic flights out of Knoxville McGhee Tyson?

From Knoxville McGhee Tyson, you can take domestic flights to many cities. Searches reveal that momondo users prefer flights to Jacksonville, Orlando, Fort Lauderdale, Washington, D.C., and Chicago the most.

What are the cheapest cities to fly to from Knoxville?

The cheapest city to fly to from Knoxville currently is Orlando at $32. The next cheapest destinations are Washington, D.C., Austin, Philadelphia, Jacksonville and Houston.

Frequently asked questions regarding flights from Knoxville

Which airlines are currently offering the cheapest flights from Knoxville?

Our data suggests that currently, the cheapest flights from Knoxville are being offered by Allegiant Air, American Airlines, and Delta. For example, Allegiant Air flights from Knoxville to South Bend, start at $31, American Airlines flights from Knoxville to Washington, D.C. cost around $50, and Delta flights from Knoxville to Valparaiso, Florida are around $69.

What is the cheapest flight available from Knoxville?

Currently, the cheapest flight from Knoxville found by our users is for $32 to Orlando Sanford Intl Airport. Prices will vary according to several factors such as the departure date and time, but on average you can expect to pay around $135 to travel from Knoxville to Orlando Sanford Intl Airport.

Which destinations have the most frequent flights from Knoxville?

Atlanta, Chicago and Chicago O'Hare Intl Airport are currently the destinations served most frequently from Knoxville, with 34, 32 and 32 flights per day on average, respectively.

Which airlines can you fly with from Knoxville?

Airlines including American Airlines, United Airlines and Delta frequently fly from Knoxville. You can view other airlines by performing a quick search in the form above.

What is the cheapest first class flight from Knoxville?

If you are looking for a cheap first class flight, consider flights to Atlanta, for which the starting price of a first class seat can be as low as $599.

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport?

Prices for flights from Knoxville McGhee Tyson Airport are refreshed on a daily basis.

How many operators does momondo search for flights from Knoxville McGhee Tyson Airport?

As of June 2026, there are 24 operators available to choose from for flights from Knoxville McGhee Tyson Airport.

How old do you have to be to fly from Knoxville McGhee Tyson Airport?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport.

What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.