Cheap flights from Knoxville (TYS) from $49

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Route

Depart

Return

Price

Cheapest one-way

KnoxvilleFort Lauderdale

TYS Knoxville McGhee Tyson - FLL Fort Lauderdale

TYSFLL

Knoxville McGhee Tyson

Fri 10/23

9:28 pm-11:29 pm

Nonstop2h 01m

$49

KnoxvilleFort Lauderdale

TYS Knoxville McGhee Tyson - FLL Fort Lauderdale

TYSFLL

Knoxville McGhee Tyson

Wed 10/14

4:14 pm-6:15 pm

Nonstop2h 01m

$50

KnoxvilleOrlando

TYS Knoxville McGhee Tyson - MCO Orlando

TYSMCO

Knoxville McGhee Tyson

Sat 12/5

7:20 pm-11:49 pm

1 stop4h 29m

$79

KnoxvilleOrlando

TYS Knoxville McGhee Tyson - MCO Orlando

TYSMCO

Knoxville McGhee Tyson

Tue 11/10

2:13 pm-7:18 pm

1 stop5h 05m

$79

Quickest one-way

KnoxvilleOrlando

TYS Knoxville McGhee Tyson - MCO Orlando

TYSMCO

Knoxville McGhee Tyson

Tue 11/10

1:00 pm-2:50 pm

Nonstop1h 50m

$104

KnoxvilleOrlando

TYS Knoxville McGhee Tyson - MCO Orlando

TYSMCO

Knoxville McGhee Tyson

Tue 11/17

1:00 pm-2:50 pm

Nonstop1h 50m

$104

KnoxvilleOrlando

TYS Knoxville McGhee Tyson - MCO Orlando

TYSMCO

Knoxville McGhee Tyson

Thu 11/5

6:33 pm-8:10 am

2 stops37h 37m

$106

KnoxvilleOrlando

TYS Knoxville McGhee Tyson - MCO Orlando

TYSMCO

Knoxville McGhee Tyson

Mon 12/7

11:00 am-12:17 pm

1 stop25h 17m

$107

KnoxvilleOrlando

TYS Knoxville McGhee Tyson - MCO Orlando

TYSMCO

Knoxville McGhee Tyson

Thu 10/29

8:35 am-12:00 pm

1 stop3h 25m

$109

KnoxvilleOrlando

TYS Knoxville McGhee Tyson - MCO Orlando

TYSMCO

Knoxville McGhee Tyson

Thu 11/5

5:40 am-9:59 am

1 stop4h 19m

$109

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

Where can I directly fly to from Knoxville?

Currently, 13 destinations can be reached directly via flights from Knoxville.

Flights from Knoxville to

Austin

from$46

Flights from Knoxville to

Boston

from$60

Flights from Knoxville to

Fort Lauderdale

from$67

Flights from Knoxville to

Jacksonville

from$41

Flights from Knoxville to

Key West

from$82

Flights from Knoxville to

Las Vegas

from$113

Flights from Knoxville to

Memphis

from$42

Flights from Knoxville to

New Haven

from$69

Flights from Knoxville to

Philadelphia

from$78

Flights from Knoxville to

Punta Gorda

from$85

Flights from Knoxville to

Sarasota

from$74

Flights from Knoxville to

Tampa

from$46

Flights from Knoxville to

Valparaiso, Florida

from$108

Find the cheapest flights from Knoxville

One-way

Last minute

International

Domestic

Cheap one-way flights from Knoxville

Enter your travel dates to find the best prices.

9:28 pm - 11:29 pmTYS Knoxville McGhee Tyson-FLL Fort Lauderdale

2h 01mnonstop

$49Allegiant Air

Fri, Oct 23

4:14 pm - 6:15 pmTYS Knoxville McGhee Tyson-FLL Fort Lauderdale

2h 01mnonstop

$50Allegiant Air

Wed, Oct 14

7:20 pm - 11:49 pmTYS Knoxville McGhee Tyson-MCO Orlando

4h 29m1 stop Charlotte Douglas

$79American Airlines

Sat, Dec 5

2:13 pm - 7:18 pmTYS Knoxville McGhee Tyson-MCO Orlando

5h 05m1 stop Charlotte Douglas

$79American Airlines

Tue, Nov 10

1:00 pm - 2:50 pmTYS Knoxville McGhee Tyson-MCO Orlando

1h 50mnonstop

$104Southwest

Tue, Nov 10

1:00 pm - 2:50 pmTYS Knoxville McGhee Tyson-MCO Orlando

1h 50mnonstop

$104Southwest

Tue, Nov 17

6:33 pm - 8:10 amTYS Knoxville McGhee Tyson-MCO Orlando

37h 37m2 stops Jacksonville Atlanta Hartsfield-Jackson

$106Multiple Airlines

Thu, Nov 5

11:00 am - 12:17 pmTYS Knoxville McGhee Tyson-MCO Orlando

25h 17m1 stop Key West

$107Multiple Airlines

Mon, Dec 7

8:35 am - 12:00 pmTYS Knoxville McGhee Tyson-MCO Orlando

3h 25m1 stop Atlanta Hartsfield-Jackson

$109Delta

Thu, Oct 29

5:40 am - 9:59 amTYS Knoxville McGhee Tyson-MCO Orlando

4h 19m1 stop Atlanta Hartsfield-Jackson

$109Delta

Thu, Nov 5

Last-minute flight deals from Knoxville

Enter your travel dates to find the best prices.

10:28 am - 12:09 pmTYS Knoxville McGhee Tyson-MCO Orlando

1h 41mnonstop

9:01 am - 10:44 amMCO Orlando-TYS Knoxville McGhee Tyson

1h 43mnonstop

$160Allegiant Air

Wed, Sep 30 - Mon, Oct 5

9:36 pm - 11:37 pmTYS Knoxville McGhee Tyson-FLL Fort Lauderdale

2h 01mnonstop

8:30 am - 10:35 amFLL Fort Lauderdale-TYS Knoxville McGhee Tyson

2h 05mnonstop

$185Allegiant Air

Sat, Oct 3 - Mon, Oct 5

1:37 pm - 4:36 pmTYS Knoxville McGhee Tyson-FLL Fort Lauderdale

26h 59m1 stop Washington, D.C. Dulles Intl

6:00 am - 8:05 amFLL Fort Lauderdale-TYS Knoxville McGhee Tyson

2h 05mnonstop

$264Multiple Airlines

Thu, Oct 1 - Sun, Oct 4

1:37 pm - 8:59 pmTYS Knoxville McGhee Tyson-FLL Fort Lauderdale

7h 22m1 stop Washington, D.C. Dulles Intl

6:00 am - 8:05 amFLL Fort Lauderdale-TYS Knoxville McGhee Tyson

2h 05mnonstop

$265Multiple Airlines

Thu, Oct 1 - Sun, Oct 4

2:00 pm - 9:03 pmTYS Knoxville McGhee Tyson-MCO Orlando

7h 03m1 stop Charlotte Douglas

6:00 am - 12:01 pmMCO Orlando-TYS Knoxville McGhee Tyson

6h 01m1 stop Charlotte Douglas

$351American Airlines

Wed, Sep 30 - Sat, Oct 3

7:15 pm - 11:59 pmTYS Knoxville McGhee Tyson-MCO Orlando

4h 44m1 stop Miami

5:50 am - 9:38 amMCO Orlando-TYS Knoxville McGhee Tyson

3h 48m1 stop Charlotte Douglas

$351American Airlines

Sat, Oct 3 - Tue, Oct 6

10:42 am - 11:40 amTYS Knoxville McGhee Tyson-ORD Chicago O'Hare Intl

1h 58mnonstop

2:10 pm - 5:08 pmORD Chicago O'Hare Intl-TYS Knoxville McGhee Tyson

1h 58mnonstop

$389United Airlines

Thu, Oct 1 - Mon, Oct 5

10:42 am - 11:40 amTYS Knoxville McGhee Tyson-ORD Chicago O'Hare Intl

1h 58mnonstop

10:30 am - 1:14 pmORD Chicago O'Hare Intl-TYS Knoxville McGhee Tyson

1h 44mnonstop

$389United Airlines

Thu, Oct 1 - Mon, Oct 5

12:23 pm - 4:37 pmTYS Knoxville McGhee Tyson-ORD Chicago O'Hare Intl

5h 14m1 stop Atlanta Hartsfield-Jackson

8:05 am - 3:26 pmORD Chicago O'Hare Intl-TYS Knoxville McGhee Tyson

6h 21m1 stop Atlanta Hartsfield-Jackson

$424Delta

Wed, Sep 30 - Tue, Oct 6

8:55 am - 12:41 pmTYS Knoxville McGhee Tyson-ORD Chicago O'Hare Intl

4h 46m1 stop Atlanta Hartsfield-Jackson

11:19 am - 6:24 pmORD Chicago O'Hare Intl-TYS Knoxville McGhee Tyson

6h 05m1 stop Detroit Metropolitan Wayne County

$424Delta

Wed, Sep 30 - Tue, Oct 6

Cheapest international flights from Knoxville

Enter your travel dates to find the best prices.

7:00 am - 7:20 amAVL Asheville Regional-MAD Madrid Barajas

18h 20m1 stop New York LaGuardia

9:20 am - 8:19 pmMAD Madrid Barajas-AVL Asheville Regional

16h 59m1 stop New York John F Kennedy Intl

$560Delta

Sun, Nov 15 - Tue, Dec 15

6:05 am - 9:45 amAVL Asheville Regional-MAD Madrid Barajas

21h 40m1 stop Atlanta Hartsfield-Jackson

9:20 am - 9:20 amMAD Madrid Barajas-AVL Asheville Regional

30h 00m2 stops New York John F Kennedy Intl Atlanta Hartsfield-Jackson

$565Delta

Mon, Nov 23 - Tue, Dec 15

10:04 am - 9:45 amAVL Asheville Regional-MAD Madrid Barajas

17h 41m1 stop Atlanta Hartsfield-Jackson

12:20 pm - 1:19 pmMAD Madrid Barajas-AVL Asheville Regional

30h 59m1 stop Atlanta Hartsfield-Jackson

$566Delta

Mon, Nov 23 - Tue, Dec 15

1:40 pm - 10:20 amCHA Chattanooga Lovell Field-CPH Kastrup Copenhagen

38h 40m2 stops Houston George Bush Intcntl Toronto Pearson Intl

11:35 am - 10:41 pmCPH Kastrup Copenhagen-CHA Chattanooga Lovell Field

41h 06m2 stops Toronto Pearson Intl Chicago O'Hare Intl

$753United Airlines

Fri, Dec 4 - Sat, Dec 12

2:00 pm - 2:40 pmAVL Asheville Regional-CPH Kastrup Copenhagen

18h 40m2 stops Atlanta Hartsfield-Jackson Paris Charles de Gaulle

8:05 am - 9:22 amCPH Kastrup Copenhagen-AVL Asheville Regional

30h 17m2 stops London Heathrow Atlanta Hartsfield-Jackson

$764Delta

Sun, Feb 28 - Sun, Mar 14

6:45 am - 5:35 pmCHA Chattanooga Lovell Field-CPH Kastrup Copenhagen

28h 50m2 stops Chicago O'Hare Intl Munich Franz Josef Strauss

11:35 am - 5:58 pmCPH Kastrup Copenhagen-CHA Chattanooga Lovell Field

36h 23m2 stops Toronto Pearson Intl Newark

$765United Airlines

Mon, Feb 1 - Fri, Feb 5

6:45 am - 6:10 pmCHA Chattanooga Lovell Field-IST Istanbul

27h 25m2 stops Chicago O'Hare Intl Frankfurt am Main

6:30 am - 9:07 pmIST Istanbul-CHA Chattanooga Lovell Field

22h 37m2 stops Frankfurt am Main Chicago O'Hare Intl

$833United Airlines

Mon, Feb 1 - Fri, Feb 5

1:59 pm - 6:10 pmCHA Chattanooga Lovell Field-IST Istanbul

20h 11m2 stops Chicago O'Hare Intl Frankfurt am Main

6:30 am - 9:07 pmIST Istanbul-CHA Chattanooga Lovell Field

22h 37m2 stops Frankfurt am Main Chicago O'Hare Intl

$834United Airlines

Mon, Feb 1 - Fri, Feb 5

10:41 am - 6:10 pmCHA Chattanooga Lovell Field-IST Istanbul

23h 29m2 stops Chicago O'Hare Intl Frankfurt am Main

6:30 am - 9:07 pmIST Istanbul-CHA Chattanooga Lovell Field

22h 37m2 stops Frankfurt am Main Chicago O'Hare Intl

$835United Airlines

Mon, Feb 1 - Fri, Feb 5

5:35 am - 2:05 pmCHA Chattanooga Lovell Field-HND Tokyo Haneda

18h 30m1 stop Atlanta Hartsfield-Jackson

5:35 pm - 10:00 pmHND Tokyo Haneda-CHA Chattanooga Lovell Field

18h 25m1 stop Detroit Metropolitan Wayne County

$879Delta

Tue, Nov 10 - Tue, Nov 17

Cheapest domestic flights from Knoxville

Enter your travel dates to find the best prices.

7:04 pm - 9:05 pmTYS Knoxville McGhee Tyson-FLL Fort Lauderdale

2h 01mnonstop

8:00 am - 10:05 amFLL Fort Lauderdale-TYS Knoxville McGhee Tyson

2h 05mnonstop

$99Allegiant Air

Tue, Oct 13 - Sat, Oct 31

9:36 pm - 11:37 pmTYS Knoxville McGhee Tyson-FLL Fort Lauderdale

2h 01mnonstop

8:00 am - 10:05 amFLL Fort Lauderdale-TYS Knoxville McGhee Tyson

2h 05mnonstop

$100Allegiant Air

Sat, Oct 10 - Sat, Oct 31

9:28 pm - 11:29 pmTYS Knoxville McGhee Tyson-FLL Fort Lauderdale

2h 01mnonstop

6:20 am - 8:25 amFLL Fort Lauderdale-TYS Knoxville McGhee Tyson

2h 05mnonstop

$102Allegiant Air

Fri, Oct 23 - Sun, Oct 25

9:49 pm - 11:25 pmTYS Knoxville McGhee Tyson-SFB Orlando Sanford Intl

1h 36mnonstop

7:18 pm - 8:59 pmSFB Orlando Sanford Intl-TYS Knoxville McGhee Tyson

1h 41mnonstop

$108Allegiant Air

Mon, Dec 7 - Mon, Dec 14

9:10 am - 11:05 amTYS Knoxville McGhee Tyson-EWR Newark

1h 55mnonstop

11:55 am - 1:58 pmEWR Newark-TYS Knoxville McGhee Tyson

2h 03mnonstop

$108Allegiant Air

Wed, Oct 21 - Wed, Oct 28

7:04 pm - 9:05 pmTYS Knoxville McGhee Tyson-FLL Fort Lauderdale

2h 01mnonstop

3:09 pm - 5:14 pmFLL Fort Lauderdale-TYS Knoxville McGhee Tyson

2h 05mnonstop

$109Allegiant Air

Tue, Oct 20 - Tue, Oct 27

9:10 am - 11:05 amTYS Knoxville McGhee Tyson-EWR Newark

1h 55mnonstop

11:55 am - 1:58 pmEWR Newark-TYS Knoxville McGhee Tyson

2h 03mnonstop

$110Allegiant Air

Wed, Oct 21 - Wed, Oct 28

5:39 pm - 7:12 pmTYS Knoxville McGhee Tyson-SFB Orlando Sanford Intl

1h 33mnonstop

7:13 pm - 8:50 pmSFB Orlando Sanford Intl-TYS Knoxville McGhee Tyson

1h 37mnonstop

$111Allegiant Air

Mon, Oct 19 - Sat, Oct 24

9:10 am - 11:05 amTYS Knoxville McGhee Tyson-EWR Newark

1h 55mnonstop

11:55 am - 1:58 pmEWR Newark-TYS Knoxville McGhee Tyson

2h 03mnonstop

$111Allegiant Air

Wed, Oct 21 - Wed, Oct 28

8:30 am - 10:07 amTYS Knoxville McGhee Tyson-SFB Orlando Sanford Intl

1h 37mnonstop

7:57 pm - 9:35 pmSFB Orlando Sanford Intl-TYS Knoxville McGhee Tyson

1h 38mnonstop

$112Allegiant Air

Tue, Nov 10 - Thu, Nov 12

Flights from Knoxville - Travel Insights & Trends

Get data-powered insights and trends into flights from Knoxville to help you craft the best travel plan.

Prices

Other information

What are the most popular domestic flights out of Knoxville McGhee Tyson?

From Knoxville McGhee Tyson, you can take domestic flights to many cities. Searches reveal that momondo users prefer flights to Jacksonville, Sarasota, Orlando, Washington, D.C., and Fort Lauderdale the most.

What are the cheapest cities to fly to from Knoxville?

The cheapest city to fly to from Knoxville currently is Jacksonville at $41. The next cheapest destinations are Memphis, Tampa, Austin, Orlando and Boston.

Frequently asked questions regarding flights from Knoxville

Which airlines are currently offering the cheapest flights from Knoxville?

Our data suggests that currently, the cheapest flights from Knoxville are being offered by Delta, Allegiant Air, and American Airlines. For example, Delta flights from Knoxville to Memphis, start at $41, Allegiant Air flights from Knoxville to Washington, D.C. Dulles Intl Airport cost around $46, and American Airlines flights from Knoxville to Washington, D.C. are around $50.

What is the cheapest flight available from Knoxville?

Currently, the cheapest flight from Knoxville found by our users is for $41 to Jacksonville. Prices will vary according to several factors such as the departure date and time, but on average you can expect to pay around $104 to travel from Knoxville to Jacksonville.

Which destinations have the most frequent flights from Knoxville?

Atlanta, Washington, D.C. and Chicago O'Hare Intl Airport are currently the destinations served most frequently from Knoxville, with 28, 21 and 20 flights per day on average, respectively.

Which airlines can you fly with from Knoxville?

Airlines including American Airlines, Delta and United Airlines frequently fly from Knoxville. You can view other airlines by performing a quick search in the form above.

What is the cheapest first class flight from Knoxville?

If you are looking for a cheap first class flight, consider flights to Chicago O'Hare Intl Airport, for which the starting price of a first class seat can be as low as $680.

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport?

Prices for flights from Knoxville McGhee Tyson Airport are refreshed on a daily basis.

How many operators does momondo search for flights from Knoxville McGhee Tyson Airport?

As of September 2026, there are 25 operators available to choose from for flights from Knoxville McGhee Tyson Airport.

How old do you have to be to fly from Knoxville McGhee Tyson Airport?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport.

What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.