What airlines fly to South America?

American Airlines, Delta and Spirit Airlines are the top three most popular airlines that fly to South America from Wilmington according to our data. American Airlines is the first choice among our users, with 67% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 3 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Wilmington New Hanover County to South America?

American Airlines and United Airlines are the most popular carriers operating from Wilmington New Hanover County to South America

When did momondo last update prices for flights from Wilmington New Hanover County Airport to South America?

Prices for flights from Wilmington New Hanover County Airport to South America are refreshed on a daily basis.

How many operators does momondo search for flights from Wilmington New Hanover County Airport to South America?

As of April 2026, there are 2 operators available to choose from for flights from Wilmington New Hanover County Airport to South America.

How old do you have to be to fly from Wilmington New Hanover County Airport to South America?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Wilmington New Hanover County Airport to South America.

What documentation or ID do you need to fly to South America?

The travel and health documents you'll need for your trip to South America may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at South America. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$509 Cheap Flights from Wilmington to South America in 2026

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Find the cheapest flights from Wilmington to South America

Round-trip

One-way

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:00 am - 12:36 pm

ILM

MDE

7h 36m

1 stop

3:05 pm - 11:18 pm

MDE

ILM

7h 13m

1 stop

$561American Airlines

Sat, Sep 26 - Sat, Oct 3

6:17 am - 8:00 pm

ILM

MDE

14h 43m

2 stops

3:05 pm - 11:18 pm

MDE

ILM

7h 13m

1 stop

$566American Airlines

Sat, Sep 26 - Sat, Oct 3

7:18 am - 8:00 pm

ILM

MDE

13h 42m

2 stops

3:05 pm - 10:19 am

MDE

ILM

18h 14m

2 stops

$576American Airlines

Sat, Sep 26 - Sat, Oct 3

6:00 am - 4:43 am

ILM

UIO

23h 43m

2 stops

12:59 am - 11:06 am

UIO

ILM

9h 07m

1 stop

$810LATAM Airlines

Tue, May 19 - Fri, May 22

4:46 pm - 4:43 am

ILM

UIO

12h 57m

2 stops

12:59 am - 1:36 pm

UIO

ILM

11h 37m

1 stop

$850LATAM Airlines

Sat, May 16 - Mon, May 25

9:45 pm - 4:17 am

ILM

SCL

30h 32m

3 stops

1:11 am - 8:56 pm

SCL

ILM

43h 45m

3 stops

$1,064Multiple Airlines

Thu, May 21 - Fri, May 29

9:45 pm - 4:17 am

ILM

SCL

30h 32m

3 stops

6:40 am - 4:43 pm

SCL

ILM

34h 03m

3 stops

$1,086Multiple Airlines

Thu, May 21 - Sat, May 30

6:00 am - 6:25 am

ILM

SCL

24h 25m

2 stops

10:55 pm - 11:24 pm

SCL

ILM

24h 29m

2 stops

$1,190Delta

Sat, May 23 - Sun, May 31

4:05 pm - 2:30 am

ILM

MAO

34h 25m

2 stops

3:35 am - 3:24 pm

MAO

ILM

35h 49m

2 stops

$1,539United Airlines

Thu, May 28 - Sun, May 31

6:00 am - 11:25 pm

ILM

UIO

18h 25m

2 stops

7:25 am - 3:22 pm

UIO

ILM

30h 57m

2 stops

$2,925United Airlines

Tue, May 19 - Sat, May 23

LATAM Airlines flights from Wilmington to South America

Our best LATAM Airlines deals on Wilmington to South America flight tickets

LATAM Airlines

Sep 27

ILM6:00 amWilmington New Hanover County

23h 43m

2 stops

UIO4:43 amQuito Mariscal Sucr

Oct 1

UIO6:50 pmQuito Mariscal Sucr

27h 19m

2 stops

ILM11:09 pmWilmington New Hanover County

$728

LATAM Airlines

Sep 27

ILM6:00 amWilmington New Hanover County

13h 59m

1 stop

UIO6:59 pmQuito Mariscal Sucr

Oct 1

UIO6:50 pmQuito Mariscal Sucr

27h 19m

2 stops

ILM11:09 pmWilmington New Hanover County

$738

LATAM Airlines

Sep 27

ILM6:00 amWilmington New Hanover County

13h 59m

1 stop

UIO6:59 pmQuito Mariscal Sucr

Sep 30

UIO12:59 amQuito Mariscal Sucr

11h 39m

1 stop

ILM1:38 pmWilmington New Hanover County

$803

American Airlines flights from Wilmington to South America

Our best American Airlines deals on Wilmington to South America flight tickets

American Airlines

Sep 26

ILM6:00 amWilmington New Hanover County

7h 36m

1 stop

MDE12:36 pmMedellín Jose Maria Cordova Intl

Oct 3

MDE3:05 pmMedellín Jose Maria Cordova Intl

7h 13m

1 stop

ILM11:18 pmWilmington New Hanover County

$561

American Airlines

Sep 26

ILM6:17 amWilmington New Hanover County

14h 43m

2 stops

MDE8:00 pmMedellín Jose Maria Cordova Intl

Oct 3

MDE3:05 pmMedellín Jose Maria Cordova Intl

7h 13m

1 stop

ILM11:18 pmWilmington New Hanover County

$566

American Airlines

Sep 26

ILM7:18 amWilmington New Hanover County

13h 42m

2 stops

MDE8:00 pmMedellín Jose Maria Cordova Intl

Oct 3

MDE3:05 pmMedellín Jose Maria Cordova Intl

18h 14m

2 stops

ILM10:19 amWilmington New Hanover County

$576

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Quickest round-trip

WilmingtonMedellín

ILM - MDE

ILMMDE

Wilmington New Hanover County

Sat 9/26

6:00 am-12:36 pm

1 stop7h 36m

Medellín Jose Maria Cordova Intl

Sat 10/3

3:05 pm-11:18 pm

1 stop7h 13m

$561

WilmingtonMedellín

ILM - MDE

ILMMDE

Wilmington New Hanover County

Sat 9/26

6:17 am-8:00 pm

2 stops14h 43m

Medellín Jose Maria Cordova Intl

Sat 10/3

3:05 pm-11:18 pm

1 stop7h 13m

$566

WilmingtonMedellín

ILM - MDE

ILMMDE

Wilmington New Hanover County

Sat 9/26

7:18 am-8:00 pm

2 stops13h 42m

Medellín Jose Maria Cordova Intl

Sat 10/3

3:05 pm-10:19 am

2 stops18h 14m

$576

WilmingtonQuito

ILM - UIO

ILMUIO

Wilmington New Hanover County

Tue 5/19

6:00 am-4:43 am

2 stops23h 43m

Quito Mariscal Sucr

Fri 5/22

12:59 am-11:06 am

1 stop9h 07m

$810

WilmingtonQuito

ILM - UIO

ILMUIO

Wilmington New Hanover County

Sat 5/16

4:46 pm-4:43 am

2 stops12h 57m

Quito Mariscal Sucr

Mon 5/25

12:59 am-1:36 pm

1 stop11h 37m

$850

WilmingtonSantiago

ILM - SCL

ILMSCL

Wilmington New Hanover County

Thu 5/21

9:45 pm-4:17 am

3 stops30h 32m

Santiago Arturo Merino Benitez

Fri 5/29

1:11 am-8:56 pm

3 stops43h 45m

$1,064

WilmingtonSantiago

ILM - SCL

ILMSCL

Wilmington New Hanover County

Thu 5/21

9:45 pm-4:17 am

3 stops30h 32m

Santiago Arturo Merino Benitez

Sat 5/30

6:40 am-4:43 pm

3 stops34h 03m

$1,086

WilmingtonSantiago

ILM - SCL

ILMSCL

Wilmington New Hanover County

Sat 5/23

6:00 am-6:25 am

2 stops24h 25m

Santiago Arturo Merino Benitez

Sun 5/31

10:55 pm-11:24 pm

2 stops24h 29m

$1,190

WilmingtonManaus

ILM - MAO

ILMMAO

Wilmington New Hanover County

Thu 5/28

4:05 pm-2:30 am

2 stops34h 25m

Manaus Eduardo Gomes Intl

Sun 5/31

3:35 am-3:24 pm

2 stops35h 49m

$1,539

WilmingtonQuito

ILM - UIO

ILMUIO

Wilmington New Hanover County

Tue 5/19

6:00 am-11:25 pm

2 stops18h 25m

Quito Mariscal Sucr

Sat 5/23

7:25 am-3:22 pm

2 stops30h 57m

$2,925

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 17 resultsSorted by cheapest first

How to get the cheapest flight ticket from Wilmington to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Can stopping save me money on Wilmington to South America flights?

You could potentially save up to 27% on your flight if you consider stops on a Wilmington to South America flight.

Cheap Wilmington to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Wilmington to South America

Fastest flight time	14h 17m
Direct flights	None

The fastest flight from Wilmington to South America takes 14h 17m

There are no direct flights from Wilmington to South America. There are no popular flight routes from Wilmington to South America.

Search flight deals

Frequently asked questions about flying from Wilmington to South America

When did momondo last update prices for flights from Wilmington New Hanover County Airport to South America?
Prices for flights from Wilmington New Hanover County Airport to South America are refreshed on a daily basis.
How many operators does momondo search for flights from Wilmington New Hanover County Airport to South America?
As of April 2026, there are 2 operators available to choose from for flights from Wilmington New Hanover County Airport to South America.
How old do you have to be to fly from Wilmington New Hanover County Airport to South America?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Wilmington New Hanover County Airport to South America.
What documentation or ID do you need to fly to South America?
The travel and health documents you'll need for your trip to South America may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at South America. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Wilmington to South America

Compare and see reviews for airlines that fly from Wilmington to South America with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $531	Free Cancellation	Rating 7.9 8,386 reviews		Search Delta flights
American Airlines	PriceFrom $547	Free Cancellation	Rating 7.1 11,555 reviews		Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Wilmington to South America?

Finding the right flight to South America from Wilmington is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to South America quick and easy, saving you time and money.

Can I find flights from Wilmington to South America with flexible booking policies on momondo?

Yes. All flights to South America from Wilmington on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Wilmington to South America?

momondo provides multiple filters to help you find the best flight to South America from Wilmington. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Wilmington to South America right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Wilmington to South America flights. All you need is a valid email address and we will do the rest; it is that quick and easy.