Cheap flights from the United States to South America from $90

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from the United States to South America departing on 4/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from the United States to South America

Recent round-trip flight deals from the United States to South America

Enter your travel dates to find the best prices.
Spirit Airlines Logo
6:50 am - 12:52 pm
FLL
-
MDE
7h 02m
1 stop
Spirit Airlines Logo
2:17 pm - 6:50 pm
MDE
-
FLL
3h 33mnonstop
$189Spirit Airlines
Sat, Mar 28 - Mon, Apr 6
Spirit Airlines Logo
11:00 am - 1:22 pm
FLL
-
MDE
3h 22mnonstop
Spirit Airlines Logo
1:17 am - 5:50 am
MDE
-
FLL
3h 33mnonstop
$194Spirit Airlines
Fri, Mar 20 - Mon, Mar 30
Avianca Logo
7:50 pm - 10:15 pm
MIA
-
MDE
3h 25mnonstop
Avianca Logo
11:50 pm - 4:20 am
MDE
-
MIA
3h 30mnonstop
$236Avianca
Thu, Apr 16 - Tue, Apr 21
Avianca Logo
7:50 pm - 10:15 pm
MIA
-
MDE
3h 25mnonstop
Avianca Logo
11:50 pm - 4:20 am
MDE
-
MIA
3h 30mnonstop
$238Avianca
Tue, May 26 - Sat, May 30
American Airlines Logo
8:08 pm - 10:39 pm
MIA
-
MDE
3h 31mnonstop
American Airlines Logo
12:20 am - 4:53 am
MDE
-
MIA
3h 33mnonstop
$243American Airlines
Sun, Mar 8 - Fri, Mar 13
Copa Airlines Logo
6:00 am - 10:55 am
MIA
-
MDE
5h 55m
1 stop
Copa Airlines Logo
6:20 pm - 1:41 am
MDE
-
MIA
6h 21m
1 stop
$245Copa Airlines
Wed, Apr 1 - Wed, Apr 15
American Airlines Logo
11:35 pm - 4:10 am
MIA
-
LIM
5h 35mnonstop
American Airlines Logo
11:45 pm - 6:40 am
LIM
-
MIA
5h 55mnonstop
$282American Airlines
Mon, Apr 13 - Sat, Apr 25
LATAM Airlines Logo
12:15 am - 5:00 am
MIA
-
LIM
5h 45mnonstop
LATAM Airlines Logo
8:15 am - 3:20 pm
LIM
-
MIA
6h 05mnonstop
$283LATAM Airlines
Wed, Apr 8 - Thu, Apr 23
LATAM Airlines Logo
1:53 pm - 4:45 pm
MIA
-
BOG
3h 52mnonstop
LATAM Airlines Logo
7:00 am - 11:51 am
BOG
-
MIA
3h 51mnonstop
$288LATAM Airlines
Tue, Mar 10 - Sun, Mar 15
Copa Airlines Logo
6:01 am - 12:25 pm
MIA
-
LIM
7h 24m
1 stop
Copa Airlines Logo
1:20 pm - 10:23 pm
LIM
-
MIA
8h 03m
1 stop
$292Copa Airlines
Wed, Mar 11 - Sun, Apr 5

Delta flights from United States to South America

Our best Delta deals on United States to South America flight tickets
Delta
May 22
MIA5:30 pmMiami
3h 40m
BOG8:10 pmBogotá El Dorado
Jun 2
BOG8:40 amBogotá El Dorado
3h 55m
MIA1:35 pmMiami
$301
Delta
Mar 8
MIA5:37 pmMiami
3h 43m
BOG8:20 pmBogotá El Dorado
Apr 16
BOG11:00 amBogotá El Dorado
3h 55m
MIA3:55 pmMiami
$302
Delta
Mar 6
MIA12:53 pmMiami
3h 52m
BOG4:45 pmBogotá El Dorado
Mar 8
BOG7:00 amBogotá El Dorado
3h 51m
MIA11:51 amMiami
$303

LATAM Airlines flights from United States to South America

Our best LATAM Airlines deals on United States to South America flight tickets
LATAM Airlines
Apr 8
MIA12:15 amMiami
5h 45m
LIM5:00 amLima J Chavez Intl
Apr 23
LIM8:15 amLima J Chavez Intl
6h 05m
MIA3:20 pmMiami
$283
LATAM Airlines
Mar 5
MIA12:53 pmMiami
3h 52m
BOG4:45 pmBogotá El Dorado
Mar 18
BOG7:00 amBogotá El Dorado
3h 51m
MIA11:51 amMiami
$287
LATAM Airlines
Mar 10
MIA1:53 pmMiami
3h 52m
BOG4:45 pmBogotá El Dorado
Mar 15
BOG7:00 amBogotá El Dorado
3h 51m
MIA11:51 amMiami
$288

momondo Fare Finder

 
Customize your flight search to find flights from United States to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 26, 2026.
Use the filters below to find and compare flights from the United States to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Fort LauderdaleMedellín

FLL - MDE

FLLMDE

Fort Lauderdale

Sat 3/28

6:50 am-12:52 pm

1 stop7h 02m

Medellín Jose Maria Cordova Intl

Mon 4/6

2:17 pm-6:50 pm

Nonstop3h 33m

$189

Fort LauderdaleMedellín

FLL - MDE

FLLMDE

Fort Lauderdale

Fri 3/20

11:00 am-1:22 pm

Nonstop3h 22m

Medellín Jose Maria Cordova Intl

Mon 3/30

1:17 am-5:50 am

Nonstop3h 33m

$194

MiamiMedellín

MIA - MDE

MIAMDE

Miami

Thu 4/16

7:50 pm-10:15 pm

Nonstop3h 25m

Medellín Jose Maria Cordova Intl

Tue 4/21

11:50 pm-4:20 am

Nonstop3h 30m

$236

MiamiMedellín

MIA - MDE

MIAMDE

Miami

Tue 5/26

7:50 pm-10:15 pm

Nonstop3h 25m

Medellín Jose Maria Cordova Intl

Sat 5/30

11:50 pm-4:20 am

Nonstop3h 30m

$238

MiamiMedellín

MIA - MDE

MIAMDE

Miami

Sun 3/8

8:08 pm-10:39 pm

Nonstop3h 31m

Medellín Jose Maria Cordova Intl

Fri 3/13

12:20 am-4:53 am

Nonstop3h 33m

$243

MiamiMedellín

MIA - MDE

MIAMDE

Miami

Wed 4/1

6:00 am-10:55 am

1 stop5h 55m

Medellín Jose Maria Cordova Intl

Wed 4/15

6:20 pm-1:41 am

1 stop6h 21m

$245

MiamiLima

MIA - LIM

MIALIM

Miami

Mon 4/13

11:35 pm-4:10 am

Nonstop5h 35m

Lima J Chavez Intl

Sat 4/25

11:45 pm-6:40 am

Nonstop5h 55m

$282

MiamiLima

MIA - LIM

MIALIM

Miami

Wed 4/8

12:15 am-5:00 am

Nonstop5h 45m

Lima J Chavez Intl

Thu 4/23

8:15 am-3:20 pm

Nonstop6h 05m

$283

MiamiBogotá

MIA - BOG

MIABOG

Miami

Tue 3/10

1:53 pm-4:45 pm

Nonstop3h 52m

Bogotá El Dorado

Sun 3/15

7:00 am-11:51 am

Nonstop3h 51m

$288

MiamiLima

MIA - LIM

MIALIM

Miami

Wed 3/11

6:01 am-12:25 pm

1 stop7h 24m

Lima J Chavez Intl

Sun 4/5

1:20 pm-10:23 pm

1 stop8h 03m

$292

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from United States to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South America?

In general, January is the cheapest month to fly from United States to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $530. If you aren’t able to travel during the month of January, then book flights to South America from United States during September instead. Flights to South America in September, while not as cheap as those in January, still average around $573.

What is the cheapest day to depart on your flight to South America?

The cheapest day to depart from United States to South America is on a Wednesday when prices can be found for as low as $890. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from United States to South America for around $992.

What is the cheapest time of day to depart on your flight to South America?

Our data shows that the cheapest United States to South America flights are usually those with departure times in the morning. Our users have found flights to South America in the morning for as low as $904. If you have a flexible travel schedule, then try to avoid flying in the evening when prices are $980 on average. Flights to South America from United States in the evening are generally more expensive because this time of day is more convenient for travelers’ schedules.

What is the cheapest United States to South America flight route?

Fly from Orlando to Medellín Jose Maria Cordova Intl for the best United States - South America flight prices

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from United States when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $655 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from United States for as low as $601 on momondo.

What cabin class options are available on United States to South America flights?

There are 4 cabin classes available to choose from on United States to South America flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on United States to South America flights?

You could potentially save up to 13% on your flight if you consider stops on a United States to South America flight.

  • When did momondo last update prices for flights from United States to South America?

    Prices for flights from United States to South America were last updated today.

  • How many operators does momondo search for flights from United States to South America?

  • How old do you have to be to fly from United States to South America?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from United States to South America.

  • What documentation or ID do you need to fly to South America?

    The necessary travel and health documents for your South America trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from United States to South America?

Best airlines flying from United States to South America

Compare and see reviews for airlines that fly from United States to South America with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $54Free CancellationRating
5.7
3,041 reviews
Search Frontier flights
Spirit AirlinesPriceFrom $102Free CancellationRating
6.3
8,492 reviews
Search Spirit Airlines flights
ArajetPriceFrom $106Free CancellationRating
6.4
46 reviews
Search Arajet flights
DeltaPriceFrom $117Free CancellationRating
7.9
8,243 reviews
Search Delta flights
VolarisPriceFrom $143Free CancellationRating
6.6
1,171 reviews
Search Volaris flights
United AirlinesPriceFrom $150Free CancellationRating
7.4
9,350 reviews
Search United Airlines flights
JetBluePriceFrom $154Free CancellationRating
7.2
2,896 reviews
Search JetBlue flights
Copa AirlinesPriceFrom $154Free CancellationRating
7.5
1,557 reviews
Search Copa Airlines flights
AviancaPriceFrom $162Free CancellationRating
6.6
2,497 reviews
Search Avianca flights
LATAM AirlinesPriceFrom $162Free CancellationRating
7.5
1,921 reviews
Search LATAM Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from United States to South America?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from United States to South America. momondo saves you time and could save you money on your trip.

Can I find flights from United States to South America with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for United States to South America flights to just show those with flexible booking policies.

How can momondo help me find flights from United States to South America?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from United States to South America.

I’m not ready to book a flight from United States to South America right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of United States to South America flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your South America trip

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1 adult
Sat 3/28
Sat 4/4

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Popular flights according to clicks in the last 7 days on momondo