What airlines fly to Knoxville?

Allegiant Air, American Airlines and Delta are the top three most popular airlines that fly to Knoxville from Tampa according to our data. Allegiant Air is the first choice among our users, with 73% of people opting to fly with this airline when traveling to Knoxville. Keep in mind that there are 4 different airlines that fly to Knoxville on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Tampa to Knoxville McGhee Tyson?

Delta and American Airlines are the most popular carriers operating from Tampa to Knoxville McGhee Tyson

When did momondo last update prices for flights from Tampa Airport to Knoxville McGhee Tyson Airport?

Prices for flights from Tampa Airport to Knoxville McGhee Tyson Airport refresh daily.

How many operators does momondo search for flights from Tampa Airport to Knoxville McGhee Tyson Airport?

As of January 2026, there are 3 operators available to choose from for flights from Tampa Airport to Knoxville McGhee Tyson Airport.

How old do you have to be to fly from Tampa Airport to Knoxville McGhee Tyson Airport?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Tampa Airport to Knoxville McGhee Tyson Airport.

What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$80 Cheap Flights from Tampa to Knoxville in 2026

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Cheap round-trip flights

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10:05 am - 3:57 pm

TPA

TYS

5h 52m1 stop

10:58 am - 5:33 pm

TYS

TPA

6h 35m1 stop

$168Multiple Airlines

Wed, Jan 28 - Wed, Feb 11

10:05 am - 3:57 pm

TPA

TYS

5h 52m1 stop

10:58 am - 5:33 pm

TYS

TPA

6h 35m1 stop

$176Multiple Airlines

Wed, Feb 4 - Wed, Feb 11

12:48 pm - 7:27 pm

TPA

TYS

30h 39m1 stop

8:13 pm - 4:41 pm

TYS

TPA

20h 28m1 stop

$182Frontier

Thu, Feb 19 - Mon, Feb 23

10:05 am - 3:57 pm

TPA

TYS

5h 52m1 stop

11:59 am - 8:49 pm

TYS

TPA

8h 50m1 stop

$184Multiple Airlines

Wed, Jan 28 - Sat, Feb 7

6:00 am - 9:45 am

TPA

TYS

3h 45m1 stop

5:17 pm - 9:09 pm

TYS

TPA

3h 52m1 stop

$185American Airlines

Tue, Feb 3 - Tue, Feb 10

8:20 am - 5:53 pm

TPA

TYS

9h 33m1 stop

1:39 pm - 12:26 am

TYS

TPA

10h 47m2 stops

$186Multiple Airlines

Thu, Jan 29 - Sun, Feb 1

9:47 pm - 5:53 pm

TPA

TYS

20h 06m2 stops

10:58 am - 5:33 pm

TYS

TPA

6h 35m1 stop

$188Multiple Airlines

Wed, Feb 4 - Wed, Feb 11

12:10 pm - 9:15 pm

TPA

TYS

9h 05m2 stops

2:25 pm - 10:50 pm

TYS

TPA

8h 25m1 stop

$190Southwest

Thu, Mar 5 - Tue, Mar 10

10:05 am - 3:57 pm

TPA

TYS

5h 52m1 stop

1:39 pm - 8:23 am

TYS

TPA

18h 44m2 stops

$191Multiple Airlines

Wed, Jan 28 - Sun, Feb 1

9:30 am - 3:20 pm

TPA

TYS

5h 50m1 stop

7:11 pm - 11:24 pm

TYS

TPA

4h 13m1 stop

$193American Airlines

Fri, Feb 6 - Mon, Feb 9

American Airlines flights from Tampa to Knoxville

Our best American Airlines deals on Tampa to Knoxville flight tickets

American Airlines

Feb 3

TPA6:00 amTampa

3h 45m

1 stop

TYS9:45 amKnoxville McGhee Tyson

Feb 10

TYS5:17 pmKnoxville McGhee Tyson

3h 52m

1 stop

TPA9:09 pmTampa

$185

American Airlines

Feb 6

TPA9:30 amTampa

5h 50m

1 stop

TYS3:20 pmKnoxville McGhee Tyson

Feb 9

TYS7:11 pmKnoxville McGhee Tyson

4h 13m

1 stop

TPA11:24 pmTampa

$193

American Airlines

Jan 26

TPA11:00 amTampa

5h 49m

1 stop

TYS4:49 pmKnoxville McGhee Tyson

Jan 28

TYS4:00 pmKnoxville McGhee Tyson

5h 09m

1 stop

TPA9:09 pmTampa

$282

Delta flights from Tampa to Knoxville

Our best Delta deals on Tampa to Knoxville flight tickets

Delta

Feb 11

TPA10:04 amTampa

5h 17m

1 stop

TYS3:21 pmKnoxville McGhee Tyson

Feb 15

TYS6:55 amKnoxville McGhee Tyson

5h 47m

1 stop

TPA12:42 pmTampa

$217

Delta

Feb 2

TPA5:30 amTampa

3h 54m

1 stop

TYS9:24 amKnoxville McGhee Tyson

Feb 6

TYS11:58 amKnoxville McGhee Tyson

4h 56m

1 stop

TPA4:54 pmTampa

$220

Delta

Feb 10

TPA5:30 amTampa

3h 54m

1 stop

TYS9:24 amKnoxville McGhee Tyson

Feb 15

TYS6:55 amKnoxville McGhee Tyson

4h 38m

1 stop

TPA11:33 amTampa

$242

Fly from

Fly to

Route

Depart

Return

Price

TampaKnoxville

TPA - TYS

TPATYS

Tampa

Wed 1/28

10:05 am-3:57 pm

1 stop5h 52m

Knoxville McGhee Tyson

Wed 2/11

10:58 am-5:33 pm

1 stop6h 35m

$168

TampaKnoxville

TPA - TYS

TPATYS

Tampa

Wed 2/4

10:05 am-3:57 pm

1 stop5h 52m

Knoxville McGhee Tyson

Wed 2/11

10:58 am-5:33 pm

1 stop6h 35m

$176

TampaKnoxville

TPA - TYS

TPATYS

Tampa

Thu 2/19

12:48 pm-7:27 pm

1 stop30h 39m

Knoxville McGhee Tyson

Mon 2/23

8:13 pm-4:41 pm

1 stop20h 28m

$182

TampaKnoxville

TPA - TYS

TPATYS

Tampa

Wed 1/28

10:05 am-3:57 pm

1 stop5h 52m

Knoxville McGhee Tyson

Sat 2/7

11:59 am-8:49 pm

1 stop8h 50m

$184

TampaKnoxville

TPA - TYS

TPATYS

Tampa

Tue 2/3

6:00 am-9:45 am

1 stop3h 45m

Knoxville McGhee Tyson

Tue 2/10

5:17 pm-9:09 pm

1 stop3h 52m

$185

TampaKnoxville

TPA - TYS

TPATYS

Tampa

Thu 1/29

8:20 am-5:53 pm

1 stop9h 33m

Knoxville McGhee Tyson

Sun 2/1

1:39 pm-12:26 am

2 stops10h 47m

$186

TampaKnoxville

TPA - TYS

TPATYS

Tampa

Wed 2/4

9:47 pm-5:53 pm

2 stops20h 06m

Knoxville McGhee Tyson

Wed 2/11

10:58 am-5:33 pm

1 stop6h 35m

$188

TampaKnoxville

TPA - TYS

TPATYS

Tampa

Thu 3/5

12:10 pm-9:15 pm

2 stops9h 05m

Knoxville McGhee Tyson

Tue 3/10

2:25 pm-10:50 pm

1 stop8h 25m

$190

TampaKnoxville

TPA - TYS

TPATYS

Tampa

Wed 1/28

10:05 am-3:57 pm

1 stop5h 52m

Knoxville McGhee Tyson

Sun 2/1

1:39 pm-8:23 am

2 stops18h 44m

$191

TampaKnoxville

TPA - TYS

TPATYS

Tampa

Fri 2/6

9:30 am-3:20 pm

1 stop5h 50m

Knoxville McGhee Tyson

Mon 2/9

7:11 pm-11:24 pm

1 stop4h 13m

$193

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Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Tampa to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Knoxville?

The month of August is, on average, the cheapest month to fly to Knoxville from Tampa, with most prices found around $281. If you aren’t able to travel during the month of August, then book flights to Knoxville from Tampa during September instead. Flights to Knoxville in September, while not as cheap as those in August, still average around $283.

How far in advance should I book a flight to Knoxville?

You are more likely to see cheaper flights to Knoxville from Tampa when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $317 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Tampa for as low as $152 on momondo.

How have Tampa to Knoxville flight prices changed over time?

As of January 2026, prices for Tampa to Knoxville flights are approximately 367% more expensive when compared to flights at the same time last year.

When to book flights from Tampa to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Tampa to Knoxville according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Tampa to Knoxville (TPA to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Tampa to Knoxville

Fastest flight time	1h 45m
Direct flights	None

The fastest flight from Tampa to Knoxville takes 1h 45m

There are no direct flights from Tampa to Knoxville. There are no popular flight routes from Tampa to Knoxville.

Search flight deals

How far is Tampa to Knoxville McGhee Tyson by plane?
Knoxville McGhee Tyson is 559.5 mi away from Tampa. By plane, this route typically takes 1h 45m.
When did momondo last update prices for flights from Tampa Airport to Knoxville McGhee Tyson Airport?
Prices for flights from Tampa Airport to Knoxville McGhee Tyson Airport refresh daily.
How many operators does momondo search for flights from Tampa Airport to Knoxville McGhee Tyson Airport?
As of January 2026, there are 3 operators available to choose from for flights from Tampa Airport to Knoxville McGhee Tyson Airport.
How old do you have to be to fly from Tampa Airport to Knoxville McGhee Tyson Airport?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Tampa Airport to Knoxville McGhee Tyson Airport.
What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?
The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular airline from Tampa to Knoxville?
momondo data reveals that the most frequently booked airline on the route from Tampa to Knoxville is American Airlines, representing 49% of all bookings. The subsequent popular airlines are Delta at 27% and Allegiant Air at 24%.

Best airlines flying from Tampa to Knoxville

Compare and see reviews for airlines that fly from Tampa to Knoxville with momondo

Airline	Rating	Free Cancellation	Price
Allegiant Air	PriceFrom $85	Free Cancellation	Rating 7.2 702 reviews	Search Allegiant Air flights
Delta	PriceFrom $223	Free Cancellation	Rating 7.9 8,027 reviews	Search Delta flights
American Airlines	PriceFrom $248	Free Cancellation	Rating 7.2 11,095 reviews	Search American Airlines flights

Pigeon Forge

Gatlinburg

Cherokee

Bryson City

Morristown

Corbin

Alcoa

Maryville

Murphy

Crossville

Oak Ridge

Newport

Lenoir City

Kodak

Dandridge

Jefferson City

Clinton

Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Tampa to Knoxville?

Finding the right flight to Knoxville from Tampa is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Knoxville quick and easy, saving you time and money.

Can I find flights from Tampa to Knoxville with flexible booking policies on momondo?

All flight searches from Tampa to Knoxville on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Tampa to Knoxville?

momondo provides multiple filters to help you find the best flight to Knoxville from Tampa. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Tampa to Knoxville right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Tampa to Knoxville flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.