Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Tampa to Knoxville from $77

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Tampa to Knoxville departing on 10/29. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Tampa to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
9:58 pm - 9:21 pm
TPA
-
TYS
23h 23m
1 stop
Multiple Airlines Logo
12:57 pm - 8:53 pm
TYS
-
TPA
7h 56m
1 stop
$188Multiple Airlines
Sun, Oct 18 - Fri, Oct 23
Multiple Airlines Logo
10:37 pm - 6:35 pm
TPA
-
TYS
19h 58m
1 stop
Multiple Airlines Logo
12:52 pm - 12:35 am
TYS
-
TPA
11h 43m
2 stops
$190Multiple Airlines
Thu, Aug 27 - Thu, Sep 3
Multiple Airlines Logo
10:37 pm - 6:35 pm
TPA
-
TYS
19h 58m
1 stop
Multiple Airlines Logo
10:54 am - 7:23 am
TYS
-
TPA
20h 29m
1 stop
$192Multiple Airlines
Thu, Aug 27 - Thu, Sep 3
American Airlines Logo
7:43 pm - 11:51 pm
TPA
-
TYS
4h 08m
1 stop
American Airlines Logo
5:15 am - 10:32 am
TYS
-
TPA
5h 17m
1 stop
$275American Airlines
Thu, Sep 3 - Tue, Sep 8
American Airlines Logo
2:57 pm - 8:59 pm
TPA
-
TYS
6h 02m
1 stop
American Airlines Logo
6:06 am - 1:12 pm
TYS
-
TPA
7h 06m
1 stop
$275American Airlines
Mon, Aug 17 - Mon, Aug 24
Southwest Logo
2:15 pm - 7:25 pm
TPA
-
TYS
5h 10m
1 stop
Southwest Logo
6:10 pm - 10:50 pm
TYS
-
TPA
4h 40m
1 stop
$275Southwest
Sat, Sep 5 - Sun, Sep 6
Southwest Logo
8:10 am - 12:00 pm
TPA
-
TYS
3h 50m
1 stop
Southwest Logo
2:40 pm - 9:35 pm
TYS
-
TPA
6h 55m
1 stop
$275Southwest
Sat, Jan 23 - Wed, Jan 27
Southwest Logo
12:10 pm - 7:50 pm
TPA
-
TYS
7h 40m
1 stop
Southwest Logo
8:05 am - 5:05 pm
TYS
-
TPA
9h 00m
2 stops
$280Southwest
Tue, Aug 25 - Tue, Sep 1
Delta Logo
12:20 pm - 5:24 pm
TPA
-
TYS
5h 04m
1 stop
Delta Logo
12:34 pm - 4:15 pm
TYS
-
TPA
3h 41m
1 stop
$299Delta
Sat, Dec 5 - Thu, Dec 10
Delta Logo
7:20 am - 11:29 am
TPA
-
TYS
4h 09m
1 stop
Delta Logo
6:00 am - 12:15 pm
TYS
-
TPA
6h 15m
1 stop
$299Delta
Tue, Dec 8 - Wed, Dec 9

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

American Airlines flights from Tampa to Knoxville

Our best American Airlines deals on Tampa to Knoxville flight tickets
American Airlines
Aug 14
TPA8:00 amTampa
5h 31m
1 stop
TYS1:31 pmKnoxville McGhee Tyson
Aug 19
TYS6:05 pmKnoxville McGhee Tyson
5h 16m
1 stop
TPA11:21 pmTampa
$367
American Airlines
Aug 8
TPA2:57 pmTampa
6h 01m
1 stop
TYS8:58 pmKnoxville McGhee Tyson
Aug 11
TYS1:56 pmKnoxville McGhee Tyson
6h 01m
1 stop
TPA7:57 pmTampa
$405
American Airlines
Aug 10
TPA1:52 pmTampa
5h 01m
1 stop
TYS6:53 pmKnoxville McGhee Tyson
Aug 13
TYS7:25 pmKnoxville McGhee Tyson
3h 56m
1 stop
TPA11:21 pmTampa
$459

Southwest flights from Tampa to Knoxville

Our best Southwest deals on Tampa to Knoxville flight tickets
Southwest
Aug 14
TPA10:35 amTampa
9h 20m
2 stops
TYS7:55 pmKnoxville McGhee Tyson
Aug 19
TYS8:05 amKnoxville McGhee Tyson
9h 00m
2 stops
TPA5:05 pmTampa
$377
Southwest
Aug 8
TPA6:20 amTampa
8h 20m
2 stops
TYS2:40 pmKnoxville McGhee Tyson
Aug 10
TYS5:45 pmKnoxville McGhee Tyson
5h 00m
1 stop
TPA10:45 pmTampa
$462
Southwest
Aug 13
TPA7:00 amTampa
10h 10m
2 stops
TYS5:10 pmKnoxville McGhee Tyson
Aug 16
TYS5:55 pmKnoxville McGhee Tyson
4h 55m
1 stop
TPA10:50 pmTampa
$464

momondo Fare Finder

 
Customize your flight search to find flights from Tampa to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 1, 2026.
Use the filters below to find and compare flights from Tampa to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

TampaKnoxville

TPA - TYS

TPATYS

Tampa

Sun 10/18

9:58 pm-9:21 pm

1 stop23h 23m

Knoxville McGhee Tyson

Fri 10/23

12:57 pm-8:53 pm

1 stop7h 56m

$188

TampaKnoxville

TPA - TYS

TPATYS

Tampa

Thu 8/27

10:37 pm-6:35 pm

1 stop19h 58m

Knoxville McGhee Tyson

Thu 9/3

12:52 pm-12:35 am

2 stops11h 43m

$190

TampaKnoxville

TPA - TYS

TPATYS

Tampa

Thu 8/27

10:37 pm-6:35 pm

1 stop19h 58m

Knoxville McGhee Tyson

Thu 9/3

10:54 am-7:23 am

1 stop20h 29m

$192

TampaKnoxville

TPA - TYS

TPATYS

Tampa

Thu 9/3

7:43 pm-11:51 pm

1 stop4h 08m

Knoxville McGhee Tyson

Tue 9/8

5:15 am-10:32 am

1 stop5h 17m

$275

TampaKnoxville

TPA - TYS

TPATYS

Tampa

Mon 8/17

2:57 pm-8:59 pm

1 stop6h 02m

Knoxville McGhee Tyson

Mon 8/24

6:06 am-1:12 pm

1 stop7h 06m

$275

TampaKnoxville

TPA - TYS

TPATYS

Tampa

Sat 9/5

2:15 pm-7:25 pm

1 stop5h 10m

Knoxville McGhee Tyson

Sun 9/6

6:10 pm-10:50 pm

1 stop4h 40m

$275

TampaKnoxville

TPA - TYS

TPATYS

Tampa

Sat 1/23

8:10 am-12:00 pm

1 stop3h 50m

Knoxville McGhee Tyson

Wed 1/27

2:40 pm-9:35 pm

1 stop6h 55m

$275

TampaKnoxville

TPA - TYS

TPATYS

Tampa

Tue 8/25

12:10 pm-7:50 pm

1 stop7h 40m

Knoxville McGhee Tyson

Tue 9/1

8:05 am-5:05 pm

2 stops9h 00m

$280
Quickest round-trip

TampaKnoxville

TPA - TYS

TPATYS

Tampa

Sat 12/5

12:20 pm-5:24 pm

1 stop5h 04m

Knoxville McGhee Tyson

Thu 12/10

12:34 pm-4:15 pm

1 stop3h 41m

$299

TampaKnoxville

TPA - TYS

TPATYS

Tampa

Tue 12/8

7:20 am-11:29 am

1 stop4h 09m

Knoxville McGhee Tyson

Wed 12/9

6:00 am-12:15 pm

1 stop6h 15m

$299

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Knoxville from

How to get the cheapest flight ticket from Tampa to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Tampa and Knoxville?

Prices are currently low for flights on this route.

Typical prices usually range from $248 to $338.
The lowest price recently found on this route was $188.

What is the cheapest month to fly to Knoxville?

The month of September is, on average, the cheapest month to fly to Knoxville from Tampa, with most prices found around $283. If you aren’t able to travel during the month of September, then book flights to Knoxville from Tampa during January instead. Flights to Knoxville in January, while not as cheap as those in September, still average around $285.

What is the cheapest Tampa to Knoxville McGhee Tyson flight route?

Fly from Tampa to Knoxville McGhee Tyson for the best Tampa - Knoxville McGhee Tyson flight prices

How far in advance should I book a flight from Tampa to Knoxville?

You are more likely to see cheaper flights to Knoxville from Tampa when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $325 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Tampa for as low as $200 on momondo.

What cabin class options are available on Tampa to Knoxville flights?

There is only 1 cabin class available to choose from on Tampa to Knoxville flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Tampa to Knoxville flights?

No. A direct flight is the cheapest option for a flight between Tampa to Knoxville.

How have Tampa to Knoxville flight prices changed over time?

As of August 2026, prices for Tampa to Knoxville flights are approximately 6% cheaper when compared to flights at the same time last year.

When to book flights from Tampa to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Tampa to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Tampa to Knoxville (TPA to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Tampa to Knoxville

Fastest flight time

4h 23m

Direct flights

None
The fastest flight from Tampa to Knoxville takes 4h 23m
There are no direct flights from Tampa to Knoxville. There are no popular flight routes from Tampa to Knoxville.
Search flight deals

Frequently asked questions about flying from Tampa to Knoxville

  • How far is Tampa to Knoxville McGhee Tyson by plane?

    Knoxville McGhee Tyson is 559.5 mi away from Tampa. By plane, this route typically takes 4h 23m.

  • When did momondo last update prices for flights from Tampa Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Tampa Airport to Knoxville McGhee Tyson Airport refresh daily.

  • How many operators does momondo search for flights from Tampa Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Tampa Airport to Knoxville McGhee Tyson Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Tampa Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Tampa to Knoxville?

  • What is the most popular airline from Tampa to Knoxville?

Best airlines flying from Tampa to Knoxville

Compare and see reviews for airlines that fly from Tampa to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $80Free CancellationRating
7.3
678 reviews
Search Allegiant Air flights
SouthwestPriceFrom $241Free CancellationRating
8.0
4,229 reviews
Search Southwest flights
American AirlinesPriceFrom $248Free CancellationRating
7.1
11,848 reviews
Search American Airlines flights
DeltaPriceFrom $271Free CancellationRating
7.8
8,497 reviews
Search Delta flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Alcoa
Maryville
Crossville
Murphy
Oak Ridge
Kodak
Newport
Lenoir City
Dandridge
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Tampa to Knoxville?

Finding the right flight to Knoxville from Tampa is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Knoxville quick and easy, saving you time and money.

Can I find flights from Tampa to Knoxville with flexible booking policies on momondo?

All flight searches from Tampa to Knoxville on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Tampa to Knoxville?

momondo provides multiple filters to help you find the best flight to Knoxville from Tampa. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Tampa to Knoxville right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Tampa to Knoxville flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Knoxville trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Mon 8/31
Mon 9/7
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States