Which layover airport offers the lowest fares from Syracuse to St. Louis?

Flights via New York (LGA) offer the lowest average round-trip price of $333.

What is the cheapest airline that flies from Syracuse Hancock Intl to Lambert-St Louis?

American Airlines and United Airlines are the most popular carriers operating from Syracuse Hancock Intl to Lambert-St Louis

Which layover airport has the shortest travel time from Syracuse to St. Louis?

Flights connecting via Detroit (DTW) have the shortest average one-way travel time: 4h 46m.

Which airport is the most popular layover for flights between Syracuse and St. Louis?

Detroit (DTW) was the most common stop: 80% of momondo users choosing 1-stop flights on this route connected there.

What airlines fly to St. Louis?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to St. Louis from Syracuse according to our data. American Airlines is the first choice among our users, with 45% of people opting to fly with this airline when traveling to St. Louis. Keep in mind that there are 4 different airlines that fly to St. Louis on a routine basis, so you have a few additional options to choose from.

Which layover airport has the shortest connection time from Syracuse to St. Louis?

Detroit (DTW) has the shortest average layover time for this route: 1h 12m.

When did momondo last update prices for flights from Syracuse Hancock Intl Airport to Lambert-St Louis Airport?

Prices for flights from Syracuse Hancock Intl Airport to Lambert-St Louis Airport are updated daily.

How many operators does momondo search for flights from Syracuse Hancock Intl Airport to Lambert-St Louis Airport?

There are 3 operators available for flights from Syracuse Hancock Intl Airport to Lambert-St Louis Airport as of September 2025.

How old do you have to be to fly from Syracuse Hancock Intl Airport to Lambert-St Louis Airport?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Syracuse Hancock Intl Airport to Lambert-St Louis Airport.

What documentation or ID do you need to fly to Lambert-St Louis Airport?

The travel and health documents required for your trip to Lambert-St Louis Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Lambert-St Louis Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$172 Cheap Flights from Syracuse to St. Louis in 2025/26

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Round-trip

One-way

Last minute

Cheap round-trip flights

7:54 pm - 3:57 pmSYR-STL

21h 03m2 stops

7:45 pm - 11:08 amSTL-SYR

14h 23m2 stops

$226Frontier

Find Deal

Thu, Oct 30 - Sun, Nov 2

8:06 pm - 11:56 pmSYR-STL

4h 50m1 stop

6:00 am - 11:40 amSTL-SYR

4h 40m1 stop

$249American Airlines

Find Deal

Thu, Nov 6 - Sun, Nov 9

6:00 am - 12:35 pmSYR-STL

7h 35m1 stop

6:00 am - 1:12 pmSTL-SYR

6h 12m1 stop

$259Delta

Find Deal

Tue, Oct 14 - Sat, Oct 18

6:00 am - 9:50 amSYR-STL

4h 50m1 stop

5:59 pm - 11:17 pmSTL-SYR

4h 18m1 stop

$284Delta

Find Deal

Thu, Dec 18 - Mon, Dec 29

6:15 am - 10:49 amSYR-STL

5h 34m1 stop

6:30 am - 2:14 pmSTL-SYR

6h 44m2 stops

$285United Airlines

Find Deal

Tue, Oct 14 - Sat, Oct 18

5:30 am - 5:10 pmSYR-STL

12h 40m2 stops

5:59 pm - 11:17 pmSTL-SYR

4h 18m1 stop

$309Delta

Find Deal

Tue, Dec 16 - Mon, Dec 29

4:46 pm - 9:44 pmSYR-STL

5h 58m1 stop

6:04 am - 10:48 amSTL-SYR

3h 44m1 stop

$319American Airlines

Find Deal

Thu, Feb 26 - Sun, Mar 1

6:00 am - 9:50 amSYR-STL

4h 50m1 stop

5:59 pm - 11:17 pmSTL-SYR

4h 18m1 stop

$323Delta

Find Deal

Tue, Dec 16 - Sun, Dec 28

5:30 am - 5:10 pmSYR-STL

12h 40m2 stops

3:41 pm - 11:46 pmSTL-SYR

7h 05m1 stop

$341Delta

Find Deal

Wed, Dec 17 - Tue, Dec 30

6:30 am - 12:20 pmSYR-STL

6h 50m1 stop

3:15 pm - 9:08 pmSTL-SYR

4h 53m1 stop

$363United Airlines

Find Deal

Sat, Mar 14 - Thu, Mar 19

Frontier flights from Syracuse to St. Louis

Our best Frontier deals on Syracuse to St. Louis flight tickets

Frontier

Oct 9

SYR12:16 pmSyracuse Hancock Intl

23h 21m

1 stop

STL10:37 amLambert-St Louis

Oct 11

STL4:33 pmLambert-St Louis

26h 37m

1 stop

SYR8:10 pmSyracuse Hancock Intl

$199

Find similar

Frontier

Oct 30

SYR7:54 pmSyracuse Hancock Intl

21h 03m

2 stops

STL3:57 pmLambert-St Louis

Nov 2

STL7:45 pmLambert-St Louis

14h 23m

2 stops

SYR11:08 amSyracuse Hancock Intl

$226

Find similar

American Airlines flights from Syracuse to St. Louis

Our best American Airlines deals on Syracuse to St. Louis flight tickets

American Airlines

Nov 6

SYR5:47 pmSyracuse Hancock Intl

7h 09m

1 stop

STL11:56 pmLambert-St Louis

Nov 9

STL6:00 amLambert-St Louis

4h 40m

1 stop

SYR11:40 amSyracuse Hancock Intl

$249

Find similar

American Airlines

Feb 26

SYR4:46 pmSyracuse Hancock Intl

5h 58m

1 stop

STL9:44 pmLambert-St Louis

Mar 1

STL6:04 amLambert-St Louis

3h 44m

1 stop

SYR10:48 amSyracuse Hancock Intl

$319

Find similar

American Airlines

Feb 14

SYR5:26 pmSyracuse Hancock Intl

6h 18m

1 stop

STL10:44 pmLambert-St Louis

Feb 17

STL6:04 amLambert-St Louis

6h 57m

2 stops

SYR2:01 pmSyracuse Hancock Intl

$378

Find similar

Fly from

Fly to

Route

Depart

Return

Price

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Thu 10/30

7:54 pm-3:57 pm

2 stops21h 03m

Lambert-St Louis

Sun 11/2

7:45 pm-11:08 am

2 stops14h 23m

$226

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Thu 11/6

8:06 pm-11:56 pm

1 stop4h 50m

Lambert-St Louis

Sun 11/9

6:00 am-11:40 am

1 stop4h 40m

$249

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Tue 10/14

6:00 am-12:35 pm

1 stop7h 35m

Lambert-St Louis

Sat 10/18

6:00 am-1:12 pm

1 stop6h 12m

$259

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Thu 12/18

6:00 am-9:50 am

1 stop4h 50m

Lambert-St Louis

Mon 12/29

5:59 pm-11:17 pm

1 stop4h 18m

$284

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Tue 10/14

6:15 am-10:49 am

1 stop5h 34m

Lambert-St Louis

Sat 10/18

6:30 am-2:14 pm

2 stops6h 44m

$285

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Tue 12/16

5:30 am-5:10 pm

2 stops12h 40m

Lambert-St Louis

Mon 12/29

5:59 pm-11:17 pm

1 stop4h 18m

$309

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Thu 2/26

4:46 pm-9:44 pm

1 stop5h 58m

Lambert-St Louis

Sun 3/1

6:04 am-10:48 am

1 stop3h 44m

$319

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Tue 12/16

6:00 am-9:50 am

1 stop4h 50m

Lambert-St Louis

Sun 12/28

5:59 pm-11:17 pm

1 stop4h 18m

$323

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Wed 12/17

5:30 am-5:10 pm

2 stops12h 40m

Lambert-St Louis

Tue 12/30

3:41 pm-11:46 pm

1 stop7h 05m

$341

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Sat 3/14

6:30 am-12:20 pm

1 stop6h 50m

Lambert-St Louis

Thu 3/19

3:15 pm-9:08 pm

1 stop4h 53m

$363

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How to get the cheapest flight ticket from Syracuse to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the cheapest month to fly to St. Louis?

In general, February is the cheapest month to fly from Syracuse to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $288. The month of May is another great option to travel to St. Louis, with average flight prices from Syracuse averaging around $332.

What is the cheapest day to depart on your flight to St. Louis?

The cheapest day to depart on your flight to St. Louis is on a Friday when prices can be found for as low as $367. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $551. These prices are subject to change though, so be sure to set up a Price Alert for flights to St. Louis.

What is the cheapest time of day to depart on your flight to St. Louis?

Flying to St. Louis from Syracuse in the evening is the least expensive time of day to depart. momondo users have found prices as low as $299 when looking at flights departing in the evening. In the afternoon is when there is more demand to fly to St. Louis, so prices are often more expensive at around $439 per ticket.

How far in advance should I book a flight to St. Louis?

You are more likely to see cheaper flights to St. Louis from Syracuse when booking weeks ahead of your departure date. In general, you can expect to find flights to St. Louis for around $371 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to St. Louis from Syracuse for as low as $272 on momondo.

How have Syracuse to St. Louis flight prices changed over time?

As of September 2025, prices for Syracuse to St. Louis flights are approximately 114% more expensive when compared to flights at the same time last year.

When to book flights from Syracuse to St. Louis

Are you open to changing your travel dates? Check out the ideal times to fly from Syracuse to St. Louis according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Syracuse to St. Louis (SYR to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Syracuse to St. Louis

Direct flights	None

There are no direct flights from Syracuse to St. Louis. There are no popular flight routes from Syracuse to St. Louis.

Search flight deals

How far is Syracuse Hancock Intl to Lambert-St Louis by plane?
The distance between Syracuse Hancock Intl and Lambert-St Louis is about 793.6 mi. By plane, this route typically takes 4h 24m.
When did momondo last update prices for flights from Syracuse Hancock Intl Airport to Lambert-St Louis Airport?
Prices for flights from Syracuse Hancock Intl Airport to Lambert-St Louis Airport are updated daily.
How many operators does momondo search for flights from Syracuse Hancock Intl Airport to Lambert-St Louis Airport?
There are 3 operators available for flights from Syracuse Hancock Intl Airport to Lambert-St Louis Airport as of September 2025.
How old do you have to be to fly from Syracuse Hancock Intl Airport to Lambert-St Louis Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Syracuse Hancock Intl Airport to Lambert-St Louis Airport.
What documentation or ID do you need to fly to Lambert-St Louis Airport?
The travel and health documents required for your trip to Lambert-St Louis Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Lambert-St Louis Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular airline from Syracuse to St. Louis?
Based on momondo bookings for flights between Syracuse and St. Louis, the leading airline is Delta, making up 48% of the total bookings. Other popular airlines include American Airlines with 44% and United Airlines with 8%.

Best airlines flying from Syracuse to St. Louis

Compare and see reviews for airlines that fly from Syracuse to St. Louis with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $248	Free Cancellation	Rating 7.2 10,000 reviews	Search American Airlines flights
Delta	PriceFrom $248	Free Cancellation	Rating 7.9 7,964 reviews	Search Delta flights
United Airlines	PriceFrom $306	Free Cancellation	Rating 7.4 8,931 reviews	Search United Airlines flights

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Chesterfield

Fairview Heights

Hermann

Florissant

Maryland Heights

O'Fallon

Fenton

Collinsville

Wentzville

Alton

St. Peters

Farmington

Festus

Glencoe

Clayton

Edwardsville

Eureka

Litchfield

Shrewsbury

Why use momondo?

Why should I use momondo to find a flight deal from Syracuse to St. Louis?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Syracuse to St. Louis for you.

Can I find flights from Syracuse to St. Louis with flexible booking policies on momondo?

Flights from Syracuse to St. Louis with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Syracuse to St. Louis?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to St. Louis from Syracuse.

I’m not ready to book a flight from Syracuse to St. Louis right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to St. Louis from Syracuse. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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Cheap flights from Syracuse to St. Louis from $172

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Syracuse to St. Louis departing on 12/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Frontier flights from Syracuse to St. Louis

Our best Frontier deals on Syracuse to St. Louis flight tickets

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Our best American Airlines deals on Syracuse to St. Louis flight tickets

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How to get the cheapest flight ticket from Syracuse to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to St. Louis?

What is the cheapest day to depart on your flight to St. Louis?

What is the cheapest time of day to depart on your flight to St. Louis?

How far in advance should I book a flight to St. Louis?

How have Syracuse to St. Louis flight prices changed over time?

As of September 2025, prices for Syracuse to St. Louis flights are approximately 114% more expensive when compared to flights at the same time last year.

What is the cheapest airline that flies from Syracuse Hancock Intl to Lambert-St Louis?

American Airlines and United Airlines are the most popular carriers operating from Syracuse Hancock Intl to Lambert-St Louis

What airlines fly to St. Louis?

Which airport is the most popular layover for flights between Syracuse and St. Louis?

Detroit (DTW) was the most common stop: 80% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport offers the lowest fares from Syracuse to St. Louis?

Flights via New York (LGA) offer the lowest average round-trip price of $333.

Which layover airport has the shortest travel time from Syracuse to St. Louis?

Flights connecting via Detroit (DTW) have the shortest average one-way travel time: 4h 46m.

Which layover airport has the shortest connection time from Syracuse to St. Louis?

Detroit (DTW) has the shortest average layover time for this route: 1h 12m.

When to book flights from Syracuse to St. Louis

Cheap Syracuse to St. Louis (SYR to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Syracuse to St. Louis

Direct flights

How far is Syracuse Hancock Intl to Lambert-St Louis by plane?

When did momondo last update prices for flights from Syracuse Hancock Intl Airport to Lambert-St Louis Airport?

How many operators does momondo search for flights from Syracuse Hancock Intl Airport to Lambert-St Louis Airport?

How old do you have to be to fly from Syracuse Hancock Intl Airport to Lambert-St Louis Airport?

What documentation or ID do you need to fly to Lambert-St Louis Airport?

What is the most popular airline from Syracuse to St. Louis?

Best airlines flying from Syracuse to St. Louis

Compare and see reviews for airlines that fly from Syracuse to St. Louis with momondo

Traveling to a place near St. Louis?

Why use momondo?

Why should I use momondo to find a flight deal from Syracuse to St. Louis?

Can I find flights from Syracuse to St. Louis with flexible booking policies on momondo?

How can momondo help me find flights from Syracuse to St. Louis?

I’m not ready to book a flight from Syracuse to St. Louis right now. Can momondo alert me if prices change?

An easier way to manage your St. Louis trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

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