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Cheap flights from Syracuse to St. Louis from $178

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Syracuse to St. Louis departing on 7/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Syracuse to St. Louis

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
6:20 am - 9:37 am
SYR
-
STL
4h 17m
1 stop
Delta Logo
6:30 am - 1:01 pm
STL
-
SYR
5h 31m
1 stop
$291Delta
Sat, Aug 15 - Tue, Aug 18
American Airlines Logo
8:19 pm - 12:16 am
SYR
-
STL
4h 57m
1 stop
American Airlines Logo
5:02 pm - 12:20 am
STL
-
SYR
6h 18m
1 stop
$300American Airlines
Wed, Jul 15 - Mon, Jul 20
American Airlines Logo
8:19 pm - 12:16 am
SYR
-
STL
4h 57m
1 stop
American Airlines Logo
5:02 pm - 12:20 am
STL
-
SYR
6h 18m
1 stop
$309American Airlines
Wed, Jul 8 - Mon, Jul 13
United Airlines Logo
5:49 pm - 9:29 pm
SYR
-
STL
4h 40m
1 stop
United Airlines Logo
6:00 am - 2:15 pm
STL
-
SYR
7h 15m
2 stops
$312United Airlines
Wed, Jul 1 - Sat, Jul 4
American Airlines Logo
8:36 pm - 12:16 am
SYR
-
STL
4h 40m
1 stop
American Airlines Logo
5:58 pm - 11:59 pm
STL
-
SYR
5h 01m
1 stop
$315American Airlines
Fri, Jul 3 - Mon, Jul 6
Delta Logo
6:21 am - 9:31 am
SYR
-
STL
4h 10m
1 stop
Delta Logo
6:30 am - 1:01 pm
STL
-
SYR
5h 31m
1 stop
$334Delta
Sat, Jul 25 - Mon, Jul 27
United Airlines Logo
5:50 pm - 9:21 pm
SYR
-
STL
4h 31m
1 stop
United Airlines Logo
1:29 pm - 11:44 pm
STL
-
SYR
9h 15m
2 stops
$355United Airlines
Sat, Oct 3 - Mon, Oct 5
United Airlines Logo
5:49 pm - 9:26 pm
SYR
-
STL
4h 37m
1 stop
United Airlines Logo
1:13 pm - 11:59 pm
STL
-
SYR
9h 46m
2 stops
$357United Airlines
Wed, Jul 15 - Tue, Jul 21
United Airlines Logo
6:00 am - 12:13 pm
SYR
-
STL
7h 13m
2 stops
United Airlines Logo
10:27 am - 4:54 pm
STL
-
SYR
5h 27m
1 stop
$385United Airlines
Thu, Oct 22 - Sat, Oct 24
American Airlines Logo
8:19 pm - 12:16 am
SYR
-
STL
4h 57m
1 stop
American Airlines Logo
5:02 pm - 12:20 am
STL
-
SYR
6h 18m
1 stop
$388American Airlines
Fri, Jul 10 - Mon, Jul 13

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American Airlines flights from Syracuse to St. Louis

Our best American Airlines deals on Syracuse to St. Louis flight tickets
American Airlines
Jul 15
SYR8:19 pmSyracuse Hancock Intl
4h 57m
1 stop
STL12:16 amLambert-St Louis
Jul 20
STL5:02 pmLambert-St Louis
6h 18m
1 stop
SYR12:20 amSyracuse Hancock Intl
$300
American Airlines
Jul 8
SYR8:19 pmSyracuse Hancock Intl
4h 57m
1 stop
STL12:16 amLambert-St Louis
Jul 13
STL5:02 pmLambert-St Louis
6h 18m
1 stop
SYR12:20 amSyracuse Hancock Intl
$309
American Airlines
Jul 3
SYR8:36 pmSyracuse Hancock Intl
4h 40m
1 stop
STL12:16 amLambert-St Louis
Jul 6
STL5:58 pmLambert-St Louis
5h 01m
1 stop
SYR11:59 pmSyracuse Hancock Intl
$315

United Airlines flights from Syracuse to St. Louis

Our best United Airlines deals on Syracuse to St. Louis flight tickets
United Airlines
Jul 1
SYR6:15 amSyracuse Hancock Intl
6h 56m
1 stop
STL12:11 pmLambert-St Louis
Jul 4
STL6:00 amLambert-St Louis
6h 32m
1 stop
SYR1:32 pmSyracuse Hancock Intl
$291
United Airlines
Jul 1
SYR5:49 pmSyracuse Hancock Intl
4h 40m
1 stop
STL9:29 pmLambert-St Louis
Jul 4
STL6:00 amLambert-St Louis
7h 15m
2 stops
SYR2:15 pmSyracuse Hancock Intl
$312
United Airlines
Oct 3
SYR5:50 pmSyracuse Hancock Intl
4h 31m
1 stop
STL9:21 pmLambert-St Louis
Oct 5
STL1:29 pmLambert-St Louis
9h 15m
2 stops
SYR11:44 pmSyracuse Hancock Intl
$355

momondo Fare Finder

 
Customize your flight search to find flights from Syracuse to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 17, 2026.
Use the filters below to find and compare flights from Syracuse to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Sat 8/15

6:20 am-9:37 am

1 stop4h 17m

Lambert-St Louis

Tue 8/18

6:30 am-1:01 pm

1 stop5h 31m

$291

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Wed 7/15

8:19 pm-12:16 am

1 stop4h 57m

Lambert-St Louis

Mon 7/20

5:02 pm-12:20 am

1 stop6h 18m

$300

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Wed 7/8

8:19 pm-12:16 am

1 stop4h 57m

Lambert-St Louis

Mon 7/13

5:02 pm-12:20 am

1 stop6h 18m

$309

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Wed 7/1

5:49 pm-9:29 pm

1 stop4h 40m

Lambert-St Louis

Sat 7/4

6:00 am-2:15 pm

2 stops7h 15m

$312
Quickest round-trip

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Fri 7/3

8:36 pm-12:16 am

1 stop4h 40m

Lambert-St Louis

Mon 7/6

5:58 pm-11:59 pm

1 stop5h 01m

$315

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Sat 7/25

6:21 am-9:31 am

1 stop4h 10m

Lambert-St Louis

Mon 7/27

6:30 am-1:01 pm

1 stop5h 31m

$334

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Sat 10/3

5:50 pm-9:21 pm

1 stop4h 31m

Lambert-St Louis

Mon 10/5

1:29 pm-11:44 pm

2 stops9h 15m

$355

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Wed 7/15

5:49 pm-9:26 pm

1 stop4h 37m

Lambert-St Louis

Tue 7/21

1:13 pm-11:59 pm

2 stops9h 46m

$357

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Thu 10/22

6:00 am-12:13 pm

2 stops7h 13m

Lambert-St Louis

Sat 10/24

10:27 am-4:54 pm

1 stop5h 27m

$385

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Fri 7/10

8:19 pm-12:16 am

1 stop4h 57m

Lambert-St Louis

Mon 7/13

5:02 pm-12:20 am

1 stop6h 18m

$388

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to St. Louis from

How to get the cheapest flight ticket from Syracuse to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Syracuse and St. Louis?

What is the cheapest month to fly to St. Louis?

In general, January is the cheapest month to fly from Syracuse to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $298. The month of October is another great option to travel to St. Louis, with average flight prices from Syracuse averaging around $303.

How far in advance should I book a flight from Syracuse to St. Louis?

You are more likely to see cheaper flights to St. Louis from Syracuse when booking weeks ahead of your departure date. In general, you can expect to find flights to St. Louis for around $372 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to St. Louis from Syracuse for as low as $273 on momondo.

How have Syracuse to St. Louis flight prices changed over time?

When to book flights from Syracuse to St. Louis

Are you open to changing your travel dates? Check out the ideal times to fly from Syracuse to St. Louis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Syracuse to St. Louis (SYR to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Syracuse to St. Louis

Fastest flight time

4h 17m

Direct flights

None
The fastest flight from Syracuse to St. Louis takes 4h 17m
There are no direct flights from Syracuse to St. Louis. There are no popular flight routes from Syracuse to St. Louis.
Search flight deals

Frequently asked questions about flying from Syracuse to St. Louis

  • How far is Syracuse Hancock Intl to Lambert-St Louis by plane?

    The distance between Syracuse Hancock Intl and Lambert-St Louis is about 793.6 mi. By plane, this route typically takes 4h 17m.

  • When did momondo last update prices for flights from Syracuse Hancock Intl Airport to Lambert-St Louis Airport?

    Prices for flights from Syracuse Hancock Intl Airport to Lambert-St Louis Airport are updated daily.

  • How many operators does momondo search for flights from Syracuse Hancock Intl Airport to Lambert-St Louis Airport?

  • How old do you have to be to fly from Syracuse Hancock Intl Airport to Lambert-St Louis Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Syracuse Hancock Intl Airport to Lambert-St Louis Airport.

  • What documentation or ID do you need to fly to Lambert-St Louis Airport?

    The travel and health documents required for your trip to Lambert-St Louis Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Lambert-St Louis Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Syracuse to St. Louis?

Best airlines flying from Syracuse to St. Louis

Compare and see reviews for airlines that fly from Syracuse to St. Louis with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $218Free CancellationRating
7.4
9,845 reviews
Search United Airlines flights
American AirlinesPriceFrom $248Free CancellationRating
7.1
11,670 reviews
Search American Airlines flights
DeltaPriceFrom $248Free CancellationRating
7.8
8,406 reviews
Search Delta flights

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
St. Charles
Chesterfield
Fairview Heights
Hermann
Maryland Heights
Florissant
O'Fallon
St. Peters
Collinsville
Alton
Wentzville
Clayton
Fenton
Farmington
Festus
Eureka
Litchfield
Edwardsville
Grafton
Shrewsbury

Why use momondo?

Why should I use momondo to find a flight deal from Syracuse to St. Louis?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Syracuse to St. Louis for you.

Can I find flights from Syracuse to St. Louis with flexible booking policies on momondo?

Flights from Syracuse to St. Louis with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Syracuse to St. Louis?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to St. Louis from Syracuse.

I’m not ready to book a flight from Syracuse to St. Louis right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to St. Louis from Syracuse. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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