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Cheap flights from Syracuse to St. Louis from $249

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Syracuse to St. Louis departing on 2/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
6:15 am - 12:33 pm
SYR
-
STL
7h 18m1 stop
Delta Logo
6:35 am - 12:01 pm
STL
-
SYR
4h 26m1 stop
$249Delta
vie., feb. 6 - dom., feb. 8
American Airlines Logo
2:15 pm - 8:32 pm
SYR
-
STL
7h 17m2 stops
American Airlines Logo
6:00 am - 1:50 pm
STL
-
SYR
6h 50m1 stop
$254American Airlines
vie., feb. 6 - dom., feb. 8
American Airlines Logo
2:15 pm - 8:32 pm
SYR
-
STL
7h 17m2 stops
American Airlines Logo
6:00 am - 2:38 pm
STL
-
SYR
7h 38m2 stops
$294American Airlines
vie., feb. 6 - dom., feb. 8
American Airlines Logo
12:06 pm - 5:02 pm
SYR
-
STL
5h 56m1 stop
American Airlines Logo
6:00 am - 11:26 am
STL
-
SYR
4h 26m1 stop
$304American Airlines
sáb., ene. 10 - sáb., ene. 17
American Airlines Logo
7:25 am - 1:36 pm
SYR
-
STL
7h 11m1 stop
American Airlines Logo
4:53 pm - 11:38 pm
STL
-
SYR
5h 45m1 stop
$359American Airlines
vie., dic. 26 - mar., dic. 30
Delta Logo
6:05 am - 12:23 pm
SYR
-
STL
7h 18m1 stop
Delta Logo
3:47 pm - 11:51 pm
STL
-
SYR
7h 04m1 stop
$374Delta
vie., feb. 13 - lun., feb. 16
American Airlines Logo
5:02 pm - 9:41 pm
SYR
-
STL
5h 39m1 stop
American Airlines Logo
6:58 pm - 12:28 am
STL
-
SYR
4h 30m1 stop
$383American Airlines
vie., feb. 13 - dom., feb. 15
American Airlines Logo
5:02 pm - 9:41 pm
SYR
-
STL
5h 39m1 stop
American Airlines Logo
6:00 am - 3:46 pm
STL
-
SYR
8h 46m2 stops
$388American Airlines
vie., feb. 13 - dom., feb. 15
American Airlines Logo
3:26 pm - 11:28 pm
SYR
-
STL
9h 02m2 stops
American Airlines Logo
6:00 am - 3:46 pm
STL
-
SYR
8h 46m2 stops
$393American Airlines
jue., feb. 12 - dom., feb. 15
United Airlines Logo
5:48 am - 10:13 am
SYR
-
STL
5h 25m1 stop
United Airlines Logo
11:20 am - 11:25 pm
STL
-
SYR
11h 05m2 stops
$399United Airlines
sáb., ene. 10 - sáb., ene. 17

American Airlines flights from Syracuse to St. Louis

Our best American Airlines deals on Syracuse to St. Louis flight tickets
American Airlines
Feb 6
SYR2:15 pmSyracuse Hancock Intl
7h 17m
2 stops
STL8:32 pmLambert-St Louis
Feb 8
STL6:00 amLambert-St Louis
6h 50m
1 stop
SYR1:50 pmSyracuse Hancock Intl
$254
Find similar
American Airlines
Feb 6
SYR2:15 pmSyracuse Hancock Intl
7h 17m
2 stops
STL8:32 pmLambert-St Louis
Feb 8
STL6:00 amLambert-St Louis
7h 38m
2 stops
SYR2:38 pmSyracuse Hancock Intl
$294
Find similar
American Airlines
Jan 10
SYR12:06 pmSyracuse Hancock Intl
5h 56m
1 stop
STL5:02 pmLambert-St Louis
Jan 17
STL6:00 amLambert-St Louis
4h 26m
1 stop
SYR11:26 amSyracuse Hancock Intl
$304
Find similar

United Airlines flights from Syracuse to St. Louis

Our best United Airlines deals on Syracuse to St. Louis flight tickets
United Airlines
Dec 13
SYR5:45 amSyracuse Hancock Intl
5h 22m
1 stop
STL10:07 amLambert-St Louis
Dec 15
STL5:44 pmLambert-St Louis
4h 35m
1 stop
SYR11:19 pmSyracuse Hancock Intl
$369
Find similar
United Airlines
Dec 13
SYR1:05 pmSyracuse Hancock Intl
4h 58m
1 stop
STL5:03 pmLambert-St Louis
Dec 15
STL6:30 amLambert-St Louis
6h 44m
2 stops
SYR2:14 pmSyracuse Hancock Intl
$374
Find similar
United Airlines
Dec 13
SYR5:45 amSyracuse Hancock Intl
9h 40m
2 stops
STL2:25 pmLambert-St Louis
Dec 15
STL1:00 pmLambert-St Louis
9h 19m
2 stops
SYR11:19 pmSyracuse Hancock Intl
$379
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Syracuse to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated diciembre 11, 2025.
Use the filters below to find and compare flights from Syracuse to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

vie. 2/6

6:15 am-12:33 pm

1 stop7h 18m

Lambert-St Louis

dom. 2/8

6:35 am-12:01 pm

1 stop4h 26m

$249

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

vie. 2/6

2:15 pm-8:32 pm

2 stops7h 17m

Lambert-St Louis

dom. 2/8

6:00 am-1:50 pm

1 stop6h 50m

$254

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

vie. 2/6

2:15 pm-8:32 pm

2 stops7h 17m

Lambert-St Louis

dom. 2/8

6:00 am-2:38 pm

2 stops7h 38m

$294

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

sáb. 1/10

12:06 pm-5:02 pm

1 stop5h 56m

Lambert-St Louis

sáb. 1/17

6:00 am-11:26 am

1 stop4h 26m

$304

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

vie. 12/26

7:25 am-1:36 pm

1 stop7h 11m

Lambert-St Louis

mar. 12/30

4:53 pm-11:38 pm

1 stop5h 45m

$359

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

vie. 2/13

6:05 am-12:23 pm

1 stop7h 18m

Lambert-St Louis

lun. 2/16

3:47 pm-11:51 pm

1 stop7h 04m

$374

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

vie. 2/13

5:02 pm-9:41 pm

1 stop5h 39m

Lambert-St Louis

dom. 2/15

6:58 pm-12:28 am

1 stop4h 30m

$383

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

vie. 2/13

5:02 pm-9:41 pm

1 stop5h 39m

Lambert-St Louis

dom. 2/15

6:00 am-3:46 pm

2 stops8h 46m

$388

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

jue. 2/12

3:26 pm-11:28 pm

2 stops9h 02m

Lambert-St Louis

dom. 2/15

6:00 am-3:46 pm

2 stops8h 46m

$393

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

sáb. 1/10

5:48 am-10:13 am

1 stop5h 25m

Lambert-St Louis

sáb. 1/17

11:20 am-11:25 pm

2 stops11h 05m

$399

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to St. Louis from

How to get the cheapest flight ticket from Syracuse to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to St. Louis?

In general, February is the cheapest month to fly from Syracuse to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $291. The month of January is another great option to travel to St. Louis, with average flight prices from Syracuse averaging around $304.

What is the cheapest day to depart on your flight to St. Louis?

The cheapest day to depart on your flight to St. Louis is on a Friday when prices can be found for as low as $367. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $551. These prices are subject to change though, so be sure to set up a Price Alert for flights to St. Louis.

What is the cheapest time of day to depart on your flight to St. Louis?

Flying to St. Louis from Syracuse in the evening is the least expensive time of day to depart. momondo users have found prices as low as $299 when looking at flights departing in the evening. In the afternoon is when there is more demand to fly to St. Louis, so prices are often more expensive at around $439 per ticket.

How far in advance should I book a flight to St. Louis?

You are more likely to see cheaper flights to St. Louis from Syracuse when booking weeks ahead of your departure date. In general, you can expect to find flights to St. Louis for around $355 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to St. Louis from Syracuse for as low as $257 on momondo.

How have Syracuse to St. Louis flight prices changed over time?

As of December 2025, prices for Syracuse to St. Louis flights are approximately 140% more expensive when compared to flights at the same time last year.

When to book flights from Syracuse to St. Louis

Are you open to changing your travel dates? Check out the ideal times to fly from Syracuse to St. Louis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Syracuse to St. Louis (SYR to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Syracuse to St. Louis

Fastest flight time

4h 24m

Direct flights

None
The fastest flight from Syracuse to St. Louis takes 4h 24m
There are no direct flights from Syracuse to St. Louis. There are no popular flight routes from Syracuse to St. Louis.
Search flight deals

  • How far is Syracuse Hancock Intl to Lambert-St Louis by plane?

    The distance between Syracuse Hancock Intl and Lambert-St Louis is about 793.6 mi. By plane, this route typically takes 4h 24m.

  • When did momondo last update prices for flights from Syracuse Hancock Intl Airport to Lambert-St Louis Airport?

    Prices for flights from Syracuse Hancock Intl Airport to Lambert-St Louis Airport are updated daily.

  • How many operators does momondo search for flights from Syracuse Hancock Intl Airport to Lambert-St Louis Airport?

  • How old do you have to be to fly from Syracuse Hancock Intl Airport to Lambert-St Louis Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Syracuse Hancock Intl Airport to Lambert-St Louis Airport.

  • What documentation or ID do you need to fly to Lambert-St Louis Airport?

    The travel and health documents required for your trip to Lambert-St Louis Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Lambert-St Louis Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Syracuse to St. Louis?

Best airlines flying from Syracuse to St. Louis

Compare and see reviews for airlines that fly from Syracuse to St. Louis with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $248Free CancellationRating
7.4
9,095 reviews
Search United Airlines flights
American AirlinesPriceFrom $248Free CancellationRating
7.2
11,050 reviews
Search American Airlines flights
DeltaPriceFrom $248Free CancellationRating
7.9
8,008 reviews
Search Delta flights

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
St. Charles
Chesterfield
Hermann
Fairview Heights
Maryland Heights
O'Fallon
Florissant
Fenton
Wentzville
St. Peters
Collinsville
Alton
Farmington
Festus
Clayton
Glencoe
Edwardsville
Eureka
Litchfield
Shrewsbury

Why use momondo?

Why should I use momondo to find a flight deal from Syracuse to St. Louis?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Syracuse to St. Louis for you.

Can I find flights from Syracuse to St. Louis with flexible booking policies on momondo?

Flights from Syracuse to St. Louis with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Syracuse to St. Louis?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to St. Louis from Syracuse.

I’m not ready to book a flight from Syracuse to St. Louis right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to St. Louis from Syracuse. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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