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Cheap flights from Syracuse to St. Louis from $221

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Syracuse to St. Louis departing on 3/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:19 pm - 11:55 pm
SYR
-
STL
7h 36m
1 stop
American Airlines Logo
6:06 am - 11:40 am
STL
-
SYR
4h 34m
1 stop
$291American Airlines
Sat, Aug 15 - Tue, Aug 18
American Airlines Logo
8:21 pm - 11:54 pm
SYR
-
STL
4h 33m
1 stop
American Airlines Logo
5:40 pm - 11:47 pm
STL
-
SYR
5h 07m
1 stop
$300American Airlines
Thu, May 28 - Tue, Jun 2
American Airlines Logo
5:40 am - 11:47 am
SYR
-
STL
7h 07m
1 stop
American Airlines Logo
3:24 pm - 10:39 pm
STL
-
SYR
6h 15m
1 stop
$309American Airlines
Thu, Apr 9 - Tue, Apr 14
Delta Logo
5:40 pm - 10:29 pm
SYR
-
STL
5h 49m
1 stop
Delta Logo
9:30 am - 4:58 pm
STL
-
SYR
6h 28m
1 stop
$310Delta
Wed, Apr 29 - Mon, May 11
Delta Logo
6:00 am - 12:23 pm
SYR
-
STL
7h 23m
1 stop
Delta Logo
6:04 pm - 11:49 pm
STL
-
SYR
4h 45m
1 stop
$311Delta
Tue, May 26 - Tue, Jun 2
Delta Logo
6:00 am - 12:23 pm
SYR
-
STL
7h 23m
1 stop
Delta Logo
6:04 pm - 11:49 pm
STL
-
SYR
4h 45m
1 stop
$320Delta
Thu, May 28 - Sat, May 30
United Airlines Logo
6:15 am - 12:07 pm
SYR
-
STL
6h 52m
1 stop
United Airlines Logo
9:23 am - 4:48 pm
STL
-
SYR
6h 25m
1 stop
$326United Airlines
Sat, Aug 1 - Wed, Aug 5
Delta Logo
5:50 am - 9:46 am
SYR
-
STL
4h 56m
1 stop
Delta Logo
5:59 pm - 11:10 pm
STL
-
SYR
4h 11m
1 stop
$329Delta
Thu, Apr 9 - Mon, Apr 13
United Airlines Logo
6:00 am - 12:22 pm
SYR
-
STL
7h 22m
2 stops
United Airlines Logo
8:21 am - 1:31 pm
STL
-
SYR
4h 10m
1 stop
$331United Airlines
Wed, Apr 29 - Wed, May 6
Delta Logo
5:50 am - 9:46 am
SYR
-
STL
4h 56m
1 stop
Delta Logo
5:15 pm - 10:38 pm
STL
-
SYR
4h 23m
1 stop
$334Delta
Thu, Apr 2 - Tue, Apr 7

United Airlines flights from Syracuse to St. Louis

Our best United Airlines deals on Syracuse to St. Louis flight tickets
United Airlines
May 27
SYR5:44 pmSyracuse Hancock Intl
4h 32m
1 stop
STL9:16 pmLambert-St Louis
Jun 3
STL6:00 amLambert-St Louis
7h 15m
2 stops
SYR2:15 pmSyracuse Hancock Intl
$296
United Airlines
Apr 29
SYR6:00 amSyracuse Hancock Intl
7h 22m
2 stops
STL12:22 pmLambert-St Louis
May 6
STL8:21 amLambert-St Louis
4h 10m
1 stop
SYR1:31 pmSyracuse Hancock Intl
$331
United Airlines
May 5
SYR10:35 amSyracuse Hancock Intl
7h 04m
2 stops
STL4:39 pmLambert-St Louis
May 12
STL7:45 amLambert-St Louis
4h 46m
1 stop
SYR1:31 pmSyracuse Hancock Intl
$337

Delta flights from Syracuse to St. Louis

Our best Delta deals on Syracuse to St. Louis flight tickets
Delta
May 26
SYR6:00 amSyracuse Hancock Intl
7h 23m
1 stop
STL12:23 pmLambert-St Louis
Jun 2
STL6:04 pmLambert-St Louis
4h 45m
1 stop
SYR11:49 pmSyracuse Hancock Intl
$311
Delta
May 28
SYR6:00 amSyracuse Hancock Intl
7h 23m
1 stop
STL12:23 pmLambert-St Louis
May 30
STL6:04 pmLambert-St Louis
4h 45m
1 stop
SYR11:49 pmSyracuse Hancock Intl
$320
Delta
Apr 9
SYR5:50 amSyracuse Hancock Intl
4h 56m
1 stop
STL9:46 amLambert-St Louis
Apr 13
STL5:59 pmLambert-St Louis
4h 11m
1 stop
SYR11:10 pmSyracuse Hancock Intl
$329

momondo Fare Finder

 
Customize your flight search to find flights from Syracuse to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 18, 2026.
Use the filters below to find and compare flights from Syracuse to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Sat 8/15

5:19 pm-11:55 pm

1 stop7h 36m

Lambert-St Louis

Tue 8/18

6:06 am-11:40 am

1 stop4h 34m

$291

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Thu 5/28

8:21 pm-11:54 pm

1 stop4h 33m

Lambert-St Louis

Tue 6/2

5:40 pm-11:47 pm

1 stop5h 07m

$300

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Thu 4/9

5:40 am-11:47 am

1 stop7h 07m

Lambert-St Louis

Tue 4/14

3:24 pm-10:39 pm

1 stop6h 15m

$309

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Wed 4/29

5:40 pm-10:29 pm

1 stop5h 49m

Lambert-St Louis

Mon 5/11

9:30 am-4:58 pm

1 stop6h 28m

$310

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Tue 5/26

6:00 am-12:23 pm

1 stop7h 23m

Lambert-St Louis

Tue 6/2

6:04 pm-11:49 pm

1 stop4h 45m

$311

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Thu 5/28

6:00 am-12:23 pm

1 stop7h 23m

Lambert-St Louis

Sat 5/30

6:04 pm-11:49 pm

1 stop4h 45m

$320

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Sat 8/1

6:15 am-12:07 pm

1 stop6h 52m

Lambert-St Louis

Wed 8/5

9:23 am-4:48 pm

1 stop6h 25m

$326
Quickest round-trip

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Thu 4/9

5:50 am-9:46 am

1 stop4h 56m

Lambert-St Louis

Mon 4/13

5:59 pm-11:10 pm

1 stop4h 11m

$329

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Wed 4/29

6:00 am-12:22 pm

2 stops7h 22m

Lambert-St Louis

Wed 5/6

8:21 am-1:31 pm

1 stop4h 10m

$331

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Thu 4/2

5:50 am-9:46 am

1 stop4h 56m

Lambert-St Louis

Tue 4/7

5:15 pm-10:38 pm

1 stop4h 23m

$334

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to St. Louis from

How to get the cheapest flight ticket from Syracuse to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to St. Louis?

In general, January is the cheapest month to fly from Syracuse to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $283. The month of February is another great option to travel to St. Louis, with average flight prices from Syracuse averaging around $309.

How far in advance should I book a flight to St. Louis?

You are more likely to see cheaper flights to St. Louis from Syracuse when booking weeks ahead of your departure date. In general, you can expect to find flights to St. Louis for around $345 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to St. Louis from Syracuse for as low as $248 on momondo.

How have Syracuse to St. Louis flight prices changed over time?

When to book flights from Syracuse to St. Louis

Are you open to changing your travel dates? Check out the ideal times to fly from Syracuse to St. Louis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Syracuse to St. Louis (SYR to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Syracuse to St. Louis

Fastest flight time

4h 28m

Direct flights

None
The fastest flight from Syracuse to St. Louis takes 4h 28m
There are no direct flights from Syracuse to St. Louis. There are no popular flight routes from Syracuse to St. Louis.
Search flight deals

  • How far is Syracuse Hancock Intl to Lambert-St Louis by plane?

    The distance between Syracuse Hancock Intl and Lambert-St Louis is about 793.6 mi. By plane, this route typically takes 4h 28m.

  • When did momondo last update prices for flights from Syracuse Hancock Intl Airport to Lambert-St Louis Airport?

    Prices for flights from Syracuse Hancock Intl Airport to Lambert-St Louis Airport are updated daily.

  • How many operators does momondo search for flights from Syracuse Hancock Intl Airport to Lambert-St Louis Airport?

  • How old do you have to be to fly from Syracuse Hancock Intl Airport to Lambert-St Louis Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Syracuse Hancock Intl Airport to Lambert-St Louis Airport.

  • What documentation or ID do you need to fly to Lambert-St Louis Airport?

    The travel and health documents required for your trip to Lambert-St Louis Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Lambert-St Louis Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Syracuse to St. Louis?

Best airlines flying from Syracuse to St. Louis

Compare and see reviews for airlines that fly from Syracuse to St. Louis with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $248Free CancellationRating
7.4
9,435 reviews
Search United Airlines flights
American AirlinesPriceFrom $248Free CancellationRating
7.1
11,468 reviews
Search American Airlines flights
DeltaPriceFrom $248Free CancellationRating
7.9
8,286 reviews
Search Delta flights

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
St. Charles
Chesterfield
Hermann
Fairview Heights
Florissant
Maryland Heights
O'Fallon
Collinsville
Alton
St. Peters
Wentzville
Fenton
Farmington
Clayton
Edwardsville
Festus
Eureka
Litchfield
Shrewsbury
Grafton

Why use momondo?

Why should I use momondo to find a flight deal from Syracuse to St. Louis?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Syracuse to St. Louis for you.

Can I find flights from Syracuse to St. Louis with flexible booking policies on momondo?

Flights from Syracuse to St. Louis with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Syracuse to St. Louis?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to St. Louis from Syracuse.

I’m not ready to book a flight from Syracuse to St. Louis right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to St. Louis from Syracuse. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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