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Cheap flights from Syracuse to South Carolina from $49

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Syracuse to South Carolina departing on 1/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Syracuse to South Carolina

Cheap round-trip flights

Enter your travel dates to find the best prices.
Breeze Airways Logo
8:55 pm - 11:14 pm
SYR
-
CHS
2h 19mnonstop
Breeze Airways Logo
6:05 am - 8:13 am
CHS
-
SYR
2h 08mnonstop
$98Breeze Airways
Fri, Jan 23 - Mon, Jan 26
Breeze Airways Logo
8:55 pm - 11:14 pm
SYR
-
CHS
2h 19mnonstop
Breeze Airways Logo
6:05 am - 8:13 am
CHS
-
SYR
2h 08mnonstop
$103Breeze Airways
Fri, Jan 23 - Mon, Jan 26
Allegiant Air Logo
2:47 pm - 4:42 pm
SYR
-
MYR
1h 55mnonstop
Allegiant Air Logo
5:46 pm - 7:42 pm
MYR
-
SYR
1h 56mnonstop
$174Allegiant Air
Sun, May 31 - Thu, Jun 4
Allegiant Air Logo
2:59 pm - 4:56 pm
SYR
-
MYR
1h 57mnonstop
Allegiant Air Logo
5:46 pm - 7:42 pm
MYR
-
SYR
1h 56mnonstop
$194Allegiant Air
Thu, Jun 4 - Sun, Jun 7
Delta Logo
6:26 pm - 11:55 pm
SYR
-
GSP
5h 29m1 stop
Delta Logo
5:40 am - 11:05 am
GSP
-
SYR
5h 25m1 stop
$203Delta
Thu, Jan 15 - Tue, Jan 20
American Airlines Logo
3:56 pm - 8:54 pm
SYR
-
MYR
4h 58m1 stop
American Airlines Logo
5:29 pm - 11:27 pm
MYR
-
SYR
5h 58m1 stop
$211American Airlines
Sat, Jan 31 - Wed, Feb 4
American Airlines Logo
3:03 pm - 11:38 pm
SYR
-
MYR
8h 35m2 stops
American Airlines Logo
12:05 pm - 5:38 pm
MYR
-
SYR
5h 33m1 stop
$216American Airlines
Sat, Jan 31 - Wed, Feb 4
Delta Logo
6:26 pm - 11:55 pm
SYR
-
GSP
5h 29m1 stop
Delta Logo
6:45 pm - 11:13 pm
GSP
-
SYR
4h 28m1 stop
$233Delta
Fri, Jan 16 - Tue, Jan 20
United Airlines Logo
7:03 am - 4:52 pm
SYR
-
GSP
9h 49m2 stops
United Airlines Logo
6:35 am - 2:07 pm
GSP
-
SYR
7h 32m2 stops
$242United Airlines
Thu, Jan 15 - Tue, Jan 20
United Airlines Logo
2:42 pm - 10:46 pm
SYR
-
SAV
8h 04m2 stops
United Airlines Logo
2:13 pm - 11:25 pm
SAV
-
SYR
9h 12m2 stops
$243United Airlines
Tue, Jan 13 - Tue, Jan 20

Frontier flights from Syracuse to South Carolina

Our best Frontier deals on Syracuse to South Carolina flight tickets
Frontier
Jan 5
SYR8:12 pmSyracuse Hancock Intl
20h 30m
1 stop
CLT4:42 pmCharlotte Douglas
Jan 11
CLT8:46 pmCharlotte Douglas
17h 39m
1 stop
SYR2:25 pmSyracuse Hancock Intl
$172
Find similar
Frontier
Jan 5
SYR8:12 pmSyracuse Hancock Intl
20h 30m
1 stop
CLT4:42 pmCharlotte Douglas
Jan 9
CLT8:46 pmCharlotte Douglas
17h 39m
1 stop
SYR2:25 pmSyracuse Hancock Intl
$184
Find similar
Frontier
Jan 10
SYR3:20 pmSyracuse Hancock Intl
18h 12m
1 stop
CLT9:32 amCharlotte Douglas
Jan 11
CLT8:46 pmCharlotte Douglas
17h 39m
1 stop
SYR2:25 pmSyracuse Hancock Intl
$195
Find similar

American Airlines flights from Syracuse to South Carolina

Our best American Airlines deals on Syracuse to South Carolina flight tickets
American Airlines
Jan 23
SYR5:09 amSyracuse Hancock Intl
5h 23m
1 stop
CHS10:32 amCharleston
Jan 26
CHS6:10 amCharleston
7h 40m
2 stops
SYR1:50 pmSyracuse Hancock Intl
$202
Find similar
American Airlines
Jan 6
SYR3:03 pmSyracuse Hancock Intl
8h 04m
2 stops
CHS11:07 pmCharleston
Jan 8
CHS6:10 amCharleston
7h 40m
2 stops
SYR1:50 pmSyracuse Hancock Intl
$207
Find similar
American Airlines
Jan 31
SYR3:56 pmSyracuse Hancock Intl
4h 58m
1 stop
MYR8:54 pmMyrtle Beach Intl
Feb 4
MYR5:29 pmMyrtle Beach Intl
5h 58m
1 stop
SYR11:27 pmSyracuse Hancock Intl
$211
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Syracuse to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Syracuse to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SyracuseCharleston

SYR - CHS

SYRCHS

Syracuse Hancock Intl

Fri 1/23

8:55 pm-11:14 pm

Nonstop2h 19m

Charleston

Mon 1/26

6:05 am-8:13 am

Nonstop2h 08m

$98

SyracuseCharleston

SYR - CHS

SYRCHS

Syracuse Hancock Intl

Fri 1/23

8:55 pm-11:14 pm

Nonstop2h 19m

Charleston

Mon 1/26

6:05 am-8:13 am

Nonstop2h 08m

$103

SyracuseMyrtle Beach

SYR - MYR

SYRMYR

Syracuse Hancock Intl

Sun 5/31

2:47 pm-4:42 pm

Nonstop1h 55m

Myrtle Beach Intl

Thu 6/4

5:46 pm-7:42 pm

Nonstop1h 56m

$174

SyracuseMyrtle Beach

SYR - MYR

SYRMYR

Syracuse Hancock Intl

Thu 6/4

2:59 pm-4:56 pm

Nonstop1h 57m

Myrtle Beach Intl

Sun 6/7

5:46 pm-7:42 pm

Nonstop1h 56m

$194

SyracuseGreenville

SYR - GSP

SYRGSP

Syracuse Hancock Intl

Thu 1/15

6:26 pm-11:55 pm

1 stop5h 29m

Greenville

Tue 1/20

5:40 am-11:05 am

1 stop5h 25m

$203

SyracuseMyrtle Beach

SYR - MYR

SYRMYR

Syracuse Hancock Intl

Sat 1/31

3:56 pm-8:54 pm

1 stop4h 58m

Myrtle Beach Intl

Wed 2/4

5:29 pm-11:27 pm

1 stop5h 58m

$211

SyracuseMyrtle Beach

SYR - MYR

SYRMYR

Syracuse Hancock Intl

Sat 1/31

3:03 pm-11:38 pm

2 stops8h 35m

Myrtle Beach Intl

Wed 2/4

12:05 pm-5:38 pm

1 stop5h 33m

$216

SyracuseGreenville

SYR - GSP

SYRGSP

Syracuse Hancock Intl

Fri 1/16

6:26 pm-11:55 pm

1 stop5h 29m

Greenville

Tue 1/20

6:45 pm-11:13 pm

1 stop4h 28m

$233

SyracuseGreenville

SYR - GSP

SYRGSP

Syracuse Hancock Intl

Thu 1/15

7:03 am-4:52 pm

2 stops9h 49m

Greenville

Tue 1/20

6:35 am-2:07 pm

2 stops7h 32m

$242

SyracuseSavannah

SYR - SAV

SYRSAV

Syracuse Hancock Intl

Tue 1/13

2:42 pm-10:46 pm

2 stops8h 04m

Savannah/Hilton Head

Tue 1/20

2:13 pm-11:25 pm

2 stops9h 12m

$243

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to South Carolina from

How to get the cheapest flight ticket from Syracuse to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Syracuse is in January. Flight prices, which tend to average around $168, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of January, then book flights to South Carolina from Syracuse during November instead. Flights to South Carolina in November, while not as cheap as those in January, still average around $168.

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Monday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $145. The most expensive day to fly to South Carolina is Thursday, with ticket prices averaging around $416.

What is the cheapest time of day to depart on your flight to South Carolina?

Our data shows that the cheapest Syracuse to South Carolina flights are usually those with departure times in the evening. Our users have found flights to South Carolina in the evening for as low as $148. Try not to purchase tickets at noon because they tend to be around $305. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Syracuse Hancock Intl to South Carolina flight route?

Fly from Syracuse Hancock Intl to Myrtle Beach Intl for the best Syracuse Hancock Intl - South Carolina flight prices

How far in advance should I book a flight to South Carolina?

You are more likely to see cheaper flights to South Carolina from Syracuse when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $249 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Syracuse for as low as $151 on momondo.

What cabin class options are available on Syracuse Hancock Intl to South Carolina flights?

There is only 1 cabin class available to choose from on Syracuse Hancock Intl to South Carolina flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Syracuse to South Carolina flights?

No. A direct flight is the cheapest option for a flight between Syracuse to South Carolina.

Cheap Syracuse to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Syracuse to South Carolina

Best Price Found

$119

Fastest flight time

1h 55m

Direct flights

Mon, Tue, Thu, Fri, Sat and Sun

Airports in South Carolina

57 airports
The best one-way flight to South Carolina from Syracuse in the past 72 hours is $119. The best round-trip flight deal from Syracuse to South Carolina found on momondo in the last 72 hours is $111.
The fastest flight from Syracuse to South Carolina takes 1h 55m
Direct flights go from Syracuse to South Carolina on Monday, Tuesday, Thursday, Friday, Saturday and Sunday. The only airline offering direct flights is Breeze Airways.
There are 57 airports in South Carolina. From Syracuse there are direct flights to Myrtle Beach Intl (MYR), Charlotte Douglas (CLT), Charleston (CHS).
Search flight deals

  • When did momondo last update prices for flights from Syracuse Hancock Intl Airport to South Carolina?

    Prices for flights from Syracuse Hancock Intl Airport to South Carolina are updated daily.

  • How many operators does momondo search for flights from Syracuse Hancock Intl Airport to South Carolina?

  • How old do you have to be to fly from Syracuse Hancock Intl Airport to South Carolina?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Syracuse Hancock Intl Airport to South Carolina.

  • What documentation or ID do you need to fly to South Carolina?

    The travel and health documents you'll need for your trip to South Carolina may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at South Carolina. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Syracuse to South Carolina?

Best airlines flying from Syracuse to South Carolina

Compare and see reviews for airlines that fly from Syracuse to South Carolina with momondo
Airline
Rating
Free Cancellation
Price
JetBluePriceFrom $91Free CancellationRating
7.2
2,897 reviews
Search JetBlue flights
Breeze AirwaysPriceFrom $95Free CancellationRating
8.2
248 reviews
Search Breeze Airways flights
Allegiant AirPriceFrom $96Free CancellationRating
7.2
700 reviews
Search Allegiant Air flights
United AirlinesPriceFrom $134Free CancellationRating
7.4
9,091 reviews
Search United Airlines flights
DeltaPriceFrom $143Free CancellationRating
7.9
8,005 reviews
Search Delta flights
American AirlinesPriceFrom $198Free CancellationRating
7.2
11,054 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Syracuse to South Carolina?

It is quick and easy to find Syracuse to South Carolina flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to South Carolina that suits you.

Can I find flights from Syracuse to South Carolina with flexible booking policies on momondo?

All flight searches from Syracuse to South Carolina on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Syracuse to South Carolina?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to South Carolina from Syracuse.

I’m not ready to book a flight from Syracuse to South Carolina right now. Can momondo alert me if prices change?

If you are simply researching potential flights to South Carolina, momondo offers a useful price alert feature which will track prices for flights to South Carolina from Syracuse and alert you when they change.

An easier way to manage your South Carolina trip

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