Cheap flights from Syracuse to South Carolina from $55

The cheapest month to fly to South Carolina from Syracuse is in January. Flight prices, which tend to average around $163, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of January, then book flights to South Carolina from Syracuse during November instead. Flights to South Carolina in November, while not as cheap as those in January, still average around $168.

Our data shows that Friday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $158. The most expensive day to fly to South Carolina is Monday, with ticket prices averaging around $160.

Our data shows that the cheapest Syracuse to South Carolina flights are usually those with departure times in the evening. Our users have found flights to South Carolina in the evening for as low as $157. Try not to purchase tickets in the afternoon because they tend to be around $181. Of course, these prices can vary depending on the time of year and what airport you fly to.

Fly from Syracuse Hancock Intl to Charleston for the best Syracuse Hancock Intl - South Carolina flight prices

You are more likely to see cheaper flights to South Carolina from Syracuse when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $252 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Syracuse for as low as $185 on momondo.

There is only 1 cabin class available to choose from on Syracuse Hancock Intl to South Carolina flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Breeze Airways, Allegiant Air, and Frontier are the most popular carriers operating from Syracuse Hancock Intl to South Carolina

American Airlines, Breeze Airways and Delta are the top three most popular airlines that fly to South Carolina from Syracuse according to our data. American Airlines is the first choice among our users, with 38% of people opting to fly with this airline when traveling to South Carolina. Keep in mind that there are 8 different airlines that fly to South Carolina on a routine basis, so you have a few additional options to choose from.

2 flights are operational daily from Syracuse to South Carolina as of February 2026. The most popular departure time for this route is 8:00PM, with 100% of flights per day taking off in the evening.

The number of flights available between Syracuse and South Carolina is 18 per week as of February 2026. The most frequent departure day is Mon, with 17% of weekly flights leaving on this day.