How many flights depart from Syracuse to South Carolina on average per week?

The number of flights available between Syracuse and South Carolina is 2 per week as of November 2026. The most frequent departure day is Mon, with 50% of weekly flights leaving on this day.

What airlines fly to South Carolina?

American Airlines, Allegiant Air and Delta are the top three most popular airlines that fly to South Carolina from Syracuse according to our data. American Airlines is the first choice among our users, with 36% of people opting to fly with this airline when traveling to South Carolina. Keep in mind that there are 6 different airlines that fly to South Carolina on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Syracuse Hancock Intl to South Carolina?

Breeze Airways, American Airlines, and United Airlines are the most popular carriers operating from Syracuse Hancock Intl to South Carolina

When did momondo last update prices for flights from Syracuse Hancock Intl Airport to South Carolina?

Prices for flights from Syracuse Hancock Intl Airport to South Carolina are updated daily.

How many operators does momondo search for flights from Syracuse Hancock Intl Airport to South Carolina?

As of November 2026, there are 6 operators available to choose from for flights from Syracuse Hancock Intl Airport to South Carolina.

How old do you have to be to fly from Syracuse Hancock Intl Airport to South Carolina?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Syracuse Hancock Intl Airport to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The travel and health documents you'll need for your trip to South Carolina may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at South Carolina. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$58 Cheap Flights from Syracuse to South Carolina in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Syracuse to South Carolina

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

9:21 pm - 11:42 pmSYR Syracuse Hancock Intl-CHS Charleston

2h 21mnonstop

6:30 am - 8:39 amCHS Charleston-SYR Syracuse Hancock Intl

2h 09mnonstop

$98Breeze Airways

Fri, Jan 15 - Mon, Jan 18

9:21 pm - 11:42 pmSYR Syracuse Hancock Intl-CHS Charleston

2h 21mnonstop

6:30 am - 8:39 amCHS Charleston-SYR Syracuse Hancock Intl

2h 09mnonstop

$98Breeze Airways

Fri, Jan 22 - Mon, Jan 25

6:18 pm - 8:20 pmSYR Syracuse Hancock Intl-MYR Myrtle Beach Intl

2h 02mnonstop

3:33 pm - 5:28 pmMYR Myrtle Beach Intl-SYR Syracuse Hancock Intl

1h 55mnonstop

$153Allegiant Air

Fri, Nov 20 - Mon, Nov 23

6:18 pm - 8:20 pmSYR Syracuse Hancock Intl-MYR Myrtle Beach Intl

2h 02mnonstop

3:33 pm - 5:28 pmMYR Myrtle Beach Intl-SYR Syracuse Hancock Intl

1h 55mnonstop

$164Allegiant Air

Fri, Nov 20 - Mon, Nov 23

7:07 pm - 9:01 pmSYR Syracuse Hancock Intl-CHS Charleston

25h 54m1 stop Fort Lauderdale

6:30 am - 8:39 amCHS Charleston-SYR Syracuse Hancock Intl

2h 09mnonstop

$214Multiple Airlines

Thu, Dec 3 - Mon, Dec 7

6:56 pm - 9:45 pmSYR Syracuse Hancock Intl-CHS Charleston

26h 49m1 stop Fort Lauderdale

6:30 am - 8:39 amCHS Charleston-SYR Syracuse Hancock Intl

2h 09mnonstop

$256Multiple Airlines

Mon, Dec 21 - Fri, Dec 25

4:26 pm - 10:58 pmSYR Syracuse Hancock Intl-MYR Myrtle Beach Intl

6h 32m1 stop Charlotte Douglas

11:41 am - 4:32 pmMYR Myrtle Beach Intl-SYR Syracuse Hancock Intl

4h 51m1 stop Washington, D.C. Reagan-National

$311American Airlines

Sat, Jan 23 - Wed, Jan 27

11:20 am - 6:22 pmSYR Syracuse Hancock Intl-MYR Myrtle Beach Intl

7h 02m1 stop Philadelphia

8:07 am - 12:12 pmMYR Myrtle Beach Intl-SYR Syracuse Hancock Intl

4h 05m1 stop Charlotte Douglas

$311American Airlines

Sat, Dec 12 - Tue, Dec 15

6:00 am - 1:33 pmSYR Syracuse Hancock Intl-MYR Myrtle Beach Intl

7h 33m1 stop Atlanta Hartsfield-Jackson

6:00 am - 11:15 amMYR Myrtle Beach Intl-SYR Syracuse Hancock Intl

5h 15m1 stop Atlanta Hartsfield-Jackson

$311Delta

Wed, Dec 9 - Wed, Dec 16

6:00 am - 10:41 amSYR Syracuse Hancock Intl-MYR Myrtle Beach Intl

4h 41m1 stop Detroit Metropolitan Wayne County

6:00 am - 11:15 amMYR Myrtle Beach Intl-SYR Syracuse Hancock Intl

5h 15m1 stop Atlanta Hartsfield-Jackson

$311Delta

Sat, Dec 12 - Wed, Dec 16

Cheap last minute flights

Enter your travel dates to find the best prices.

4:15 pm - 6:17 pmSYR Syracuse Hancock Intl-MYR Myrtle Beach Intl

2h 02mnonstop

3:33 pm - 5:28 pmMYR Myrtle Beach Intl-SYR Syracuse Hancock Intl

1h 55mnonstop

$110Allegiant Air

Sun, Nov 15 - Wed, Nov 25

4:15 pm - 6:17 pmSYR Syracuse Hancock Intl-MYR Myrtle Beach Intl

2h 02mnonstop

3:33 pm - 5:28 pmMYR Myrtle Beach Intl-SYR Syracuse Hancock Intl

1h 55mnonstop

$116Allegiant Air

Sun, Nov 15 - Wed, Nov 25

4:15 pm - 6:17 pmSYR Syracuse Hancock Intl-MYR Myrtle Beach Intl

2h 02mnonstop

8:10 pm - 11:17 amMYR Myrtle Beach Intl-SYR Syracuse Hancock Intl

15h 07m1 stop Fort Lauderdale

$250Multiple Airlines

Sun, Nov 15 - Wed, Nov 25

4:15 pm - 6:17 pmSYR Syracuse Hancock Intl-MYR Myrtle Beach Intl

2h 02mnonstop

8:10 pm - 11:17 amMYR Myrtle Beach Intl-SYR Syracuse Hancock Intl

15h 07m1 stop Fort Lauderdale

$261Multiple Airlines

Sun, Nov 15 - Wed, Nov 25

9:21 pm - 11:42 pmSYR Syracuse Hancock Intl-CHS Charleston

2h 21mnonstop

6:30 am - 8:39 amCHS Charleston-SYR Syracuse Hancock Intl

2h 09mnonstop

$272Breeze Airways

Fri, Nov 13 - Mon, Nov 16

3:20 pm - 8:38 amSYR Syracuse Hancock Intl-CHS Charleston

17h 18m2 stops Raleigh-Durham Orlando

6:30 am - 8:39 amCHS Charleston-SYR Syracuse Hancock Intl

2h 09mnonstop

$406Breeze Airways

Sat, Nov 14 - Mon, Nov 16

5:33 pm - 10:37 pmSYR Syracuse Hancock Intl-CHS Charleston

5h 04m1 stop Washington, D.C. Reagan-National

5:26 pm - 10:43 pmCHS Charleston-SYR Syracuse Hancock Intl

5h 17m1 stop Charlotte Douglas

$409American Airlines

Fri, Nov 13 - Sat, Nov 21

7:43 pm - 11:57 pmSYR Syracuse Hancock Intl-CHS Charleston

4h 14m1 stop Charlotte Douglas

6:00 am - 10:46 amCHS Charleston-SYR Syracuse Hancock Intl

4h 46m1 stop Philadelphia

$409American Airlines

Fri, Nov 13 - Sat, Nov 21

5:15 pm - 10:10 pmSYR Syracuse Hancock Intl-GSP Greenville

4h 55m1 stop New York LaGuardia

6:50 pm - 10:54 pmGSP Greenville-SYR Syracuse Hancock Intl

4h 04m1 stop Detroit Metropolitan Wayne County

$411Delta

Wed, Nov 11 - Tue, Nov 24

7:08 pm - 11:59 pmSYR Syracuse Hancock Intl-CHS Charleston

4h 51m1 stop Atlanta Hartsfield-Jackson

6:53 pm - 10:54 pmCHS Charleston-SYR Syracuse Hancock Intl

4h 01m1 stop Detroit Metropolitan Wayne County

$450Delta

Sun, Nov 15 - Sat, Nov 21

Cheap direct flights

Enter your travel dates to find the best prices.

9:21 pm - 11:42 pmSYR Syracuse Hancock Intl-CHS Charleston

2h 21mnonstop

6:30 am - 8:39 amCHS Charleston-SYR Syracuse Hancock Intl

2h 09mnonstop

$98Breeze Airways

Fri, Jan 15 - Mon, Jan 18

9:21 pm - 11:42 pmSYR Syracuse Hancock Intl-CHS Charleston

2h 21mnonstop

6:30 am - 8:39 amCHS Charleston-SYR Syracuse Hancock Intl

2h 09mnonstop

$98Breeze Airways

Fri, Jan 22 - Mon, Jan 25

9:21 pm - 11:42 pmSYR Syracuse Hancock Intl-CHS Charleston

2h 21mnonstop

6:30 am - 8:39 amCHS Charleston-SYR Syracuse Hancock Intl

2h 09mnonstop

$108Breeze Airways

Mon, Dec 7 - Mon, Dec 14

9:21 pm - 11:42 pmSYR Syracuse Hancock Intl-CHS Charleston

2h 21mnonstop

6:30 am - 8:39 amCHS Charleston-SYR Syracuse Hancock Intl

2h 09mnonstop

$118Breeze Airways

Mon, Dec 7 - Mon, Dec 14

9:21 pm - 11:42 pmSYR Syracuse Hancock Intl-CHS Charleston

2h 21mnonstop

6:30 am - 8:39 amCHS Charleston-SYR Syracuse Hancock Intl

2h 09mnonstop

$118Breeze Airways

Fri, Dec 11 - Fri, Jan 22

9:21 pm - 11:42 pmSYR Syracuse Hancock Intl-CHS Charleston

2h 21mnonstop

6:30 am - 8:39 amCHS Charleston-SYR Syracuse Hancock Intl

2h 09mnonstop

$123Breeze Airways

Fri, Dec 11 - Mon, Dec 14

9:21 pm - 11:42 pmSYR Syracuse Hancock Intl-CHS Charleston

2h 21mnonstop

6:30 am - 8:39 amCHS Charleston-SYR Syracuse Hancock Intl

2h 09mnonstop

$133Breeze Airways

Fri, Dec 11 - Mon, Dec 14

6:18 pm - 8:20 pmSYR Syracuse Hancock Intl-MYR Myrtle Beach Intl

2h 02mnonstop

3:33 pm - 5:28 pmMYR Myrtle Beach Intl-SYR Syracuse Hancock Intl

1h 55mnonstop

$153Allegiant Air

Fri, Nov 20 - Mon, Nov 23

6:18 pm - 8:20 pmSYR Syracuse Hancock Intl-MYR Myrtle Beach Intl

2h 02mnonstop

3:33 pm - 5:28 pmMYR Myrtle Beach Intl-SYR Syracuse Hancock Intl

1h 55mnonstop

$164Allegiant Air

Fri, Nov 20 - Mon, Nov 23

6:18 pm - 8:20 pmSYR Syracuse Hancock Intl-MYR Myrtle Beach Intl

2h 02mnonstop

3:33 pm - 5:28 pmMYR Myrtle Beach Intl-SYR Syracuse Hancock Intl

1h 55mnonstop

$170Allegiant Air

Fri, Nov 20 - Wed, Nov 25

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Breeze Airways flights from Syracuse to South Carolina

Our best Breeze Airways deals on Syracuse to South Carolina flight tickets

Breeze Airways

Jan 15

SYR9:21 pmSyracuse Hancock Intl

2h 21m

CHS11:42 pmCharleston

Jan 18

CHS6:30 amCharleston

2h 09m

SYR8:39 amSyracuse Hancock Intl

$98

Breeze Airways

Dec 7

SYR9:21 pmSyracuse Hancock Intl

2h 21m

CHS11:42 pmCharleston

Dec 14

CHS6:30 amCharleston

2h 09m

SYR8:39 amSyracuse Hancock Intl

$108

Breeze Airways

Dec 4

SYR9:21 pmSyracuse Hancock Intl

2h 21m

CHS11:42 pmCharleston

Dec 11

CHS6:30 amCharleston

2h 09m

SYR8:39 amSyracuse Hancock Intl

$113

Delta flights from Syracuse to South Carolina

Our best Delta deals on Syracuse to South Carolina flight tickets

Delta

Mar 1

SYR6:00 amSyracuse Hancock Intl

4h 55m

1 stop

CHS10:55 amCharleston

Mar 6

CHS6:39 pmCharleston

4h 28m

1 stop

SYR11:07 pmSyracuse Hancock Intl

$337

Delta

Nov 27

SYR6:00 amSyracuse Hancock Intl

6h 26m

1 stop

CHS12:26 pmCharleston

Dec 2

CHS11:30 amCharleston

5h 09m

1 stop

SYR4:39 pmSyracuse Hancock Intl

$349

Delta

Nov 22

SYR5:29 amSyracuse Hancock Intl

6h 13m

1 stop

CHS11:42 amCharleston

Dec 2

CHS5:34 pmCharleston

6h 18m

1 stop

SYR11:52 pmSyracuse Hancock Intl

$364

momondo Fare Finder

Use the filters below to find and compare flights from Syracuse to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

SyracuseCharleston

SYR Syracuse Hancock Intl - CHS Charleston

SYRCHS

Syracuse Hancock Intl

Fri 1/15

9:21 pm-11:42 pm

Nonstop2h 21m

Charleston

Mon 1/18

6:30 am-8:39 am

Nonstop2h 09m

$98

SyracuseCharleston

SYR Syracuse Hancock Intl - CHS Charleston

SYRCHS

Syracuse Hancock Intl

Fri 1/22

9:21 pm-11:42 pm

Nonstop2h 21m

Charleston

Mon 1/25

6:30 am-8:39 am

Nonstop2h 09m

$98

Quickest round-trip

SyracuseMyrtle Beach

SYR Syracuse Hancock Intl - MYR Myrtle Beach Intl

SYRMYR

Syracuse Hancock Intl

Fri 11/20

6:18 pm-8:20 pm

Nonstop2h 02m

Myrtle Beach Intl

Mon 11/23

3:33 pm-5:28 pm

Nonstop1h 55m

$153

SyracuseMyrtle Beach

SYR Syracuse Hancock Intl - MYR Myrtle Beach Intl

SYRMYR

Syracuse Hancock Intl

Fri 11/20

6:18 pm-8:20 pm

Nonstop2h 02m

Myrtle Beach Intl

Mon 11/23

3:33 pm-5:28 pm

Nonstop1h 55m

$164

SyracuseCharleston

SYR Syracuse Hancock Intl - CHS Charleston

SYRCHS

Syracuse Hancock Intl

Thu 12/3

7:07 pm-9:01 pm

1 stop25h 54m

Charleston

Mon 12/7

6:30 am-8:39 am

Nonstop2h 09m

$214

SyracuseCharleston

SYR Syracuse Hancock Intl - CHS Charleston

SYRCHS

Syracuse Hancock Intl

Mon 12/21

6:56 pm-9:45 pm

1 stop26h 49m

Charleston

Fri 12/25

6:30 am-8:39 am

Nonstop2h 09m

$256

SyracuseMyrtle Beach

SYR Syracuse Hancock Intl - MYR Myrtle Beach Intl

SYRMYR

Syracuse Hancock Intl

Sat 1/23

4:26 pm-10:58 pm

1 stop6h 32m

Myrtle Beach Intl

Wed 1/27

11:41 am-4:32 pm

1 stop4h 51m

$311

SyracuseMyrtle Beach

SYR Syracuse Hancock Intl - MYR Myrtle Beach Intl

SYRMYR

Syracuse Hancock Intl

Sat 12/12

11:20 am-6:22 pm

1 stop7h 02m

Myrtle Beach Intl

Tue 12/15

8:07 am-12:12 pm

1 stop4h 05m

$311

SyracuseMyrtle Beach

SYR Syracuse Hancock Intl - MYR Myrtle Beach Intl

SYRMYR

Syracuse Hancock Intl

Wed 12/9

6:00 am-1:33 pm

1 stop7h 33m

Myrtle Beach Intl

Wed 12/16

6:00 am-11:15 am

1 stop5h 15m

$311

SyracuseMyrtle Beach

SYR Syracuse Hancock Intl - MYR Myrtle Beach Intl

SYRMYR

Syracuse Hancock Intl

Sat 12/12

6:00 am-10:41 am

1 stop4h 41m

Myrtle Beach Intl

Wed 12/16

6:00 am-11:15 am

1 stop5h 15m

$311

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Syracuse to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Syracuse is in January. Flight prices, which tend to average around $278, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of January, then book flights to South Carolina from Syracuse during November instead. Flights to South Carolina in November, while not as cheap as those in January, still average around $295.

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Friday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $166. The most expensive day to fly to South Carolina is Monday, with ticket prices averaging around $203.

What is the cheapest Syracuse Hancock Intl to South Carolina flight route?

Fly from Syracuse Hancock Intl to Myrtle Beach Intl for the best Syracuse Hancock Intl - South Carolina flight prices

How far in advance should I book a flight from Syracuse to South Carolina?

You are more likely to see cheaper flights to South Carolina from Syracuse when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $294 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Syracuse for as low as $252 on momondo.

What cabin class options are available on Syracuse to South Carolina flights?

There is only 1 cabin class available to choose from on Syracuse to South Carolina flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Syracuse to South Carolina flights?

No. A direct flight is the cheapest option for a flight between Syracuse to South Carolina.

Cheap Syracuse to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Syracuse to South Carolina

Best Price Found	$58
Fastest flight time	2h 00m
Direct flights	Mon, Tue, Thu, Fri and Sat
Airports in South Carolina	57 airports

The best one-way flight to South Carolina from Syracuse in the past 72 hours is $58. The best round-trip flight deal from Syracuse to South Carolina found on momondo in the last 72 hours is $98.

The fastest flight from Syracuse to South Carolina takes 2h 00m

Direct flights go from Syracuse to South Carolina on Monday, Tuesday, Thursday, Friday and Saturday. Airlines offering direct flights are: Breeze Airways and Allegiant Air.

There are 57 airports in South Carolina. From Syracuse there are direct flights to Myrtle Beach Intl (MYR), Charleston (CHS).

Search flight deals

Frequently asked questions about flying from Syracuse to South Carolina

When did momondo last update prices for flights from Syracuse Hancock Intl Airport to South Carolina?
Prices for flights from Syracuse Hancock Intl Airport to South Carolina are updated daily.
How many operators does momondo search for flights from Syracuse Hancock Intl Airport to South Carolina?
As of November 2026, there are 6 operators available to choose from for flights from Syracuse Hancock Intl Airport to South Carolina.
How old do you have to be to fly from Syracuse Hancock Intl Airport to South Carolina?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Syracuse Hancock Intl Airport to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The travel and health documents you'll need for your trip to South Carolina may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at South Carolina. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from Syracuse to South Carolina?
Based on momondo bookings for this flight route, the most popular plane model on flight routes from Syracuse to South Carolina is Airbus A319 (43.96% of total bookings). The next most popular plane models are Airbus A220-300 (24.18%), Airbus A320-100/200 (24.18%), and Boeing 737 MAX 8 (7.69%).

Best airlines flying from Syracuse to South Carolina

Compare and see reviews for airlines that fly from Syracuse to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
Breeze Airways	PriceFrom $98	Free Cancellation	Rating 8.2 323 reviews	Search Breeze Airways flights
Allegiant Air	PriceFrom $107	Free Cancellation	Rating 7.3 676 reviews	Search Allegiant Air flights
Delta	PriceFrom $116	Free Cancellation	Rating 7.8 8,700 reviews	Search Delta flights
JetBlue	PriceFrom $131	Free Cancellation	Rating 7.1 3,067 reviews	Search JetBlue flights
United Airlines	PriceFrom $195	Free Cancellation	Rating 7.3 10,477 reviews	Search United Airlines flights
American Airlines	PriceFrom $230	Free Cancellation	Rating 7.0 12,226 reviews	Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Syracuse to South Carolina?

It is quick and easy to find Syracuse to South Carolina flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to South Carolina that suits you.

Can I find flights from Syracuse to South Carolina with flexible booking policies on momondo?

All flight searches from Syracuse to South Carolina on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Syracuse to South Carolina?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to South Carolina from Syracuse.

I’m not ready to book a flight from Syracuse to South Carolina right now. Can momondo alert me if prices change?

If you are simply researching potential flights to South Carolina, momondo offers a useful price alert feature which will track prices for flights to South Carolina from Syracuse and alert you when they change.