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Cheap flights from Syracuse to Louisville from $259

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Syracuse to Louisville departing on 3/31. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Syracuse to Louisville

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:15 pm - 12:25 am
SYR
-
SDF
6h 10m
1 stop
American Airlines Logo
5:00 pm - 10:39 pm
SDF
-
SYR
5h 39m
1 stop
$289American Airlines
Sun, Apr 26 - Tue, May 5
American Airlines Logo
4:45 pm - 11:20 pm
SYR
-
SDF
6h 35m
1 stop
American Airlines Logo
8:00 pm - 12:48 am
SDF
-
SYR
4h 48m
1 stop
$299American Airlines
Tue, Mar 24 - Sat, Mar 28
Allegiant Air Logo
7:26 pm - 8:20 pm
SYR
-
SDF
24h 54m
1 stop
Allegiant Air Logo
12:20 pm - 6:36 pm
SDF
-
SYR
30h 16m
1 stop
$301Allegiant Air
Thu, May 28 - Wed, Jun 3
American Airlines Logo
4:45 pm - 11:48 pm
SYR
-
SDF
7h 03m
1 stop
American Airlines Logo
7:31 am - 2:27 pm
SDF
-
SYR
6h 56m
1 stop
$309American Airlines
Tue, May 5 - Sat, May 9
Delta Logo
5:13 pm - 9:20 pm
SYR
-
SDF
4h 07m
1 stop
Delta Logo
11:27 am - 4:50 pm
SDF
-
SYR
5h 23m
1 stop
$329Delta
Mon, Apr 27 - Wed, May 6
Allegiant Air Logo
10:21 am - 3:39 pm
SYR
-
SDF
29h 18m
1 stop
Allegiant Air Logo
12:20 pm - 6:36 pm
SDF
-
SYR
30h 16m
1 stop
$331Allegiant Air
Fri, May 29 - Wed, Jun 3
United Airlines Logo
6:00 am - 1:17 pm
SYR
-
SDF
7h 17m
2 stops
United Airlines Logo
5:35 am - 9:55 am
SDF
-
SYR
4h 20m
1 stop
$334United Airlines
Tue, Mar 24 - Sat, Mar 28
Multiple Airlines Logo
7:26 pm - 8:20 pm
SYR
-
SDF
24h 54m
1 stop
Multiple Airlines Logo
8:06 pm - 10:48 am
SDF
-
SYR
38h 42m
2 stops
$340Multiple Airlines
Thu, May 28 - Wed, Jun 3
United Airlines Logo
5:47 pm - 10:30 pm
SYR
-
SDF
4h 43m
1 stop
United Airlines Logo
5:54 am - 9:39 am
SDF
-
SYR
3h 45m
1 stop
$344United Airlines
Mon, Apr 27 - Mon, May 4
Delta Logo
6:18 am - 10:55 am
SYR
-
SDF
4h 37m
1 stop
Delta Logo
11:45 am - 4:21 pm
SDF
-
SYR
4h 36m
1 stop
$354Delta
Tue, Jun 23 - Tue, Jun 30

American Airlines flights from Syracuse to Louisville

Our best American Airlines deals on Syracuse to Louisville flight tickets
American Airlines
Apr 26
SYR6:15 pmSyracuse Hancock Intl
6h 10m
1 stop
SDF12:25 amLouisville Intl
May 5
SDF5:00 pmLouisville Intl
5h 39m
1 stop
SYR10:39 pmSyracuse Hancock Intl
$289
American Airlines
Mar 24
SYR4:45 pmSyracuse Hancock Intl
6h 35m
1 stop
SDF11:20 pmLouisville Intl
Mar 28
SDF8:00 pmLouisville Intl
4h 48m
1 stop
SYR12:48 amSyracuse Hancock Intl
$299
American Airlines
May 5
SYR4:45 pmSyracuse Hancock Intl
7h 03m
1 stop
SDF11:48 pmLouisville Intl
May 9
SDF7:31 amLouisville Intl
6h 56m
1 stop
SYR2:27 pmSyracuse Hancock Intl
$309

United Airlines flights from Syracuse to Louisville

Our best United Airlines deals on Syracuse to Louisville flight tickets
United Airlines
Mar 24
SYR6:00 amSyracuse Hancock Intl
7h 17m
2 stops
SDF1:17 pmLouisville Intl
Mar 28
SDF5:35 amLouisville Intl
4h 20m
1 stop
SYR9:55 amSyracuse Hancock Intl
$334
United Airlines
Apr 27
SYR5:47 pmSyracuse Hancock Intl
4h 43m
1 stop
SDF10:30 pmLouisville Intl
May 4
SDF5:54 amLouisville Intl
3h 45m
1 stop
SYR9:39 amSyracuse Hancock Intl
$344
United Airlines
Mar 26
SYR2:43 pmSyracuse Hancock Intl
4h 59m
1 stop
SDF7:42 pmLouisville Intl
Mar 30
SDF9:07 amLouisville Intl
11h 13m
2 stops
SYR8:20 pmSyracuse Hancock Intl
$354

momondo Fare Finder

 
Customize your flight search to find flights from Syracuse to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 14, 2026.
Use the filters below to find and compare flights from Syracuse to Louisville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Sun 4/26

6:15 pm-12:25 am

1 stop6h 10m

Louisville Intl

Tue 5/5

5:00 pm-10:39 pm

1 stop5h 39m

$289

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Tue 3/24

4:45 pm-11:20 pm

1 stop6h 35m

Louisville Intl

Sat 3/28

8:00 pm-12:48 am

1 stop4h 48m

$299

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Thu 5/28

7:26 pm-8:20 pm

1 stop24h 54m

Louisville Intl

Wed 6/3

12:20 pm-6:36 pm

1 stop30h 16m

$301

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Tue 5/5

4:45 pm-11:48 pm

1 stop7h 03m

Louisville Intl

Sat 5/9

7:31 am-2:27 pm

1 stop6h 56m

$309

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Mon 4/27

5:13 pm-9:20 pm

1 stop4h 07m

Louisville Intl

Wed 5/6

11:27 am-4:50 pm

1 stop5h 23m

$329

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Fri 5/29

10:21 am-3:39 pm

1 stop29h 18m

Louisville Intl

Wed 6/3

12:20 pm-6:36 pm

1 stop30h 16m

$331

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Tue 3/24

6:00 am-1:17 pm

2 stops7h 17m

Louisville Intl

Sat 3/28

5:35 am-9:55 am

1 stop4h 20m

$334

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Thu 5/28

7:26 pm-8:20 pm

1 stop24h 54m

Louisville Intl

Wed 6/3

8:06 pm-10:48 am

2 stops38h 42m

$340
Quickest round-trip

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Mon 4/27

5:47 pm-10:30 pm

1 stop4h 43m

Louisville Intl

Mon 5/4

5:54 am-9:39 am

1 stop3h 45m

$344

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Tue 6/23

6:18 am-10:55 am

1 stop4h 37m

Louisville Intl

Tue 6/30

11:45 am-4:21 pm

1 stop4h 36m

$354

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first
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See travel insights to Louisville from

How to get the cheapest flight ticket from Syracuse to Louisville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Louisville?

If you are unable to visit Louisville during the month of August, then departing from Syracuse during the month February is also very affordable. Most momondo users find prices during this month for around $288.

When to book flights from Syracuse to Louisville

Are you open to changing your travel dates? Check out the ideal times to fly from Syracuse to Louisville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Syracuse to Louisville (SYR to SDF) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Syracuse to Louisville

Fastest flight time

4h 08m

Direct flights

None
The fastest flight from Syracuse to Louisville takes 4h 08m
There are no direct flights from Syracuse to Louisville. There are no popular flight routes from Syracuse to Louisville.
Search flight deals

  • How far is Syracuse Hancock Intl to Louisville Intl by plane?

    Louisville Intl is 601.9 mi away from Syracuse Hancock Intl. Flights usually cover this in 4h 08m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Syracuse Hancock Intl Airport to Louisville Intl Airport?

    Prices for flights from Syracuse Hancock Intl Airport to Louisville Intl Airport are updated daily.

  • How many operators does momondo search for flights from Syracuse Hancock Intl Airport to Louisville Intl Airport?

  • How old do you have to be to fly from Syracuse Hancock Intl Airport to Louisville Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Syracuse Hancock Intl Airport to Louisville Intl Airport.

  • What documentation or ID do you need to fly to Louisville Intl Airport?

    The travel and health documents required for your trip to Louisville Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Louisville Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Syracuse to Louisville?

Best airlines flying from Syracuse to Louisville

Compare and see reviews for airlines that fly from Syracuse to Louisville with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $194Free CancellationRating
7.9
8,291 reviews
Search Delta flights
American AirlinesPriceFrom $248Free CancellationRating
7.1
11,464 reviews
Search American Airlines flights
United AirlinesPriceFrom $271Free CancellationRating
7.4
9,423 reviews
Search United Airlines flights

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
French Lick
Elizabethtown
Bardstown
West Baden Springs
Jeffersonville
New Albany
Shepherdsville
Corydon
Elizabeth
Brandenburg
Charlestown
Springfield
Georgetown

Why use momondo?

Why should I use momondo to find a flight deal from Syracuse to Louisville?

Finding the right flight to Louisville from Syracuse is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Louisville quick and easy, saving you time and money.

Can I find flights from Syracuse to Louisville with flexible booking policies on momondo?

All flight searches from Syracuse to Louisville on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Syracuse to Louisville?

momondo helps you find the best flight between Syracuse and Louisville by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Syracuse to Louisville right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Syracuse to Louisville now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Louisville and let you know when they change.

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