Latest deals
Insights
FAQs
Reviews
Price Alerts

Cheap flights from St. Louis to Florida Keys from $59

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from St. Louis to Florida Keys departing on 2/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from St. Louis to Florida Keys

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
3:49 pm - 12:26 pm
STL
-
EYW
19h 37m
1 stop
Multiple Airlines Logo
9:46 am - 7:02 am
EYW
-
STL
22h 16m
1 stop
$219Multiple Airlines
Sun, Feb 22 - Thu, Mar 5
American Airlines Logo
11:22 am - 7:12 pm
STL
-
EYW
6h 50m
1 stop
American Airlines Logo
7:42 pm - 11:58 pm
EYW
-
STL
5h 16m
1 stop
$223American Airlines
Wed, Mar 18 - Wed, Mar 25
American Airlines Logo
6:00 am - 4:30 pm
STL
-
EYW
9h 30m
2 stops
American Airlines Logo
2:01 pm - 7:30 pm
EYW
-
STL
6h 29m
1 stop
$228American Airlines
Wed, Apr 15 - Wed, Apr 22
Multiple Airlines Logo
3:49 pm - 12:26 pm
STL
-
EYW
19h 37m
1 stop
Multiple Airlines Logo
11:01 am - 6:51 am
EYW
-
STL
20h 50m
2 stops
$241Multiple Airlines
Sun, Feb 15 - Thu, Feb 19
American Airlines Logo
6:27 am - 1:49 pm
STL
-
EYW
6h 22m
1 stop
American Airlines Logo
6:45 am - 10:16 am
EYW
-
STL
4h 31m
1 stop
$251American Airlines
Mon, May 11 - Tue, May 19
United Airlines Logo
6:00 am - 3:57 pm
STL
-
EYW
8h 57m
1 stop
United Airlines Logo
3:47 pm - 9:57 pm
EYW
-
STL
7h 10m
1 stop
$259United Airlines
Sat, Apr 11 - Wed, Apr 15
Delta Logo
11:55 am - 7:42 pm
STL
-
EYW
6h 47m
1 stop
Delta Logo
6:25 pm - 11:58 pm
EYW
-
STL
6h 33m
1 stop
$266Delta
Wed, Mar 4 - Tue, Mar 10
Frontier Logo
1:09 pm - 12:47 am
STL
-
MIA
10h 38m
1 stop
Frontier Logo
7:04 pm - 1:19 pm
MIA
-
STL
19h 15m
1 stop
$290Frontier
Fri, Mar 6 - Sun, Mar 8
Southwest Logo
8:15 am - 12:00 pm
STL
-
MIA
2h 45mnonstop
Southwest Logo
6:55 am - 12:45 pm
MIA
-
STL
6h 50m
2 stops
$294Southwest
Tue, Feb 24 - Tue, Mar 3
Frontier Logo
1:59 pm - 5:14 am
STL
-
MIA
14h 15m
1 stop
Frontier Logo
6:45 am - 9:49 am
MIA
-
STL
28h 04m
1 stop
$295Frontier
Fri, Feb 27 - Thu, Mar 5

Southwest flights from St. Louis to Florida Keys

Our best Southwest deals on St. Louis to Florida Keys flight tickets
Southwest
Feb 24
STL8:15 amLambert-St Louis
2h 45m
MIA12:00 pmMiami
Mar 3
MIA6:55 amMiami
6h 50m
2 stops
STL12:45 pmLambert-St Louis
$294
Southwest
Feb 24
STL1:15 pmLambert-St Louis
7h 45m
2 stops
MIA10:00 pmMiami
Mar 3
MIA12:55 pmMiami
6h 50m
1 stop
STL6:45 pmLambert-St Louis
$304
Southwest
Mar 4
STL8:15 amLambert-St Louis
2h 45m
MIA12:00 pmMiami
Mar 9
MIA5:35 pmMiami
3h 05m
STL7:40 pmLambert-St Louis
$307

Delta flights from St. Louis to Florida Keys

Our best Delta deals on St. Louis to Florida Keys flight tickets
Delta
Mar 4
STL11:55 amLambert-St Louis
6h 47m
1 stop
EYW7:42 pmKey West
Mar 10
EYW6:25 pmKey West
6h 33m
1 stop
STL11:58 pmLambert-St Louis
$266
Delta
Feb 23
STL7:10 amLambert-St Louis
14h 37m
1 stop
MIA10:47 pmMiami
Mar 4
MIA7:15 amMiami
8h 32m
1 stop
STL2:47 pmLambert-St Louis
$321
Delta
Mar 1
STL6:00 amLambert-St Louis
7h 13m
1 stop
MIA2:13 pmMiami
Mar 4
MIA7:15 amMiami
8h 32m
1 stop
STL2:47 pmLambert-St Louis
$322

momondo Fare Finder

 
Customize your flight search to find flights from St. Louis to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from St. Louis to Florida Keys that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Sun 2/22

3:49 pm-12:26 pm

1 stop19h 37m

Key West

Thu 3/5

9:46 am-7:02 am

1 stop22h 16m

$219

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Wed 3/18

11:22 am-7:12 pm

1 stop6h 50m

Key West

Wed 3/25

7:42 pm-11:58 pm

1 stop5h 16m

$223

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Wed 4/15

6:00 am-4:30 pm

2 stops9h 30m

Key West

Wed 4/22

2:01 pm-7:30 pm

1 stop6h 29m

$228

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Sun 2/15

3:49 pm-12:26 pm

1 stop19h 37m

Key West

Thu 2/19

11:01 am-6:51 am

2 stops20h 50m

$241

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Mon 5/11

6:27 am-1:49 pm

1 stop6h 22m

Key West

Tue 5/19

6:45 am-10:16 am

1 stop4h 31m

$251

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Sat 4/11

6:00 am-3:57 pm

1 stop8h 57m

Key West

Wed 4/15

3:47 pm-9:57 pm

1 stop7h 10m

$259

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Wed 3/4

11:55 am-7:42 pm

1 stop6h 47m

Key West

Tue 3/10

6:25 pm-11:58 pm

1 stop6h 33m

$266

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Fri 3/6

1:09 pm-12:47 am

1 stop10h 38m

Miami

Sun 3/8

7:04 pm-1:19 pm

1 stop19h 15m

$290

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Tue 2/24

8:15 am-12:00 pm

Nonstop2h 45m

Miami

Tue 3/3

6:55 am-12:45 pm

2 stops6h 50m

$294

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Fri 2/27

1:59 pm-5:14 am

1 stop14h 15m

Miami

Thu 3/5

6:45 am-9:49 am

1 stop28h 04m

$295

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Florida Keys from

How to get the cheapest flight ticket from St. Louis to Florida Keys

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Florida Keys?

The month of October is another great option to travel to Florida Keys, with average flight prices from St. Louis averaging around $333.

What is the cheapest day to depart on your flight to Florida Keys?

The cheapest day to depart from St. Louis to Florida Keys is on a Sunday when prices can be found for as low as $520. The most expensive day to fly to Florida Keys is Saturday, with ticket prices averaging around $582.

What is the cheapest time of day to depart on your flight to Florida Keys?

According to our data, the cheapest time of day to fly to Florida Keys is in the evening. momondo users have found flights departing from St. Louis to Florida Keys in the evening for as low as $412. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights in the morning are often more expensive with an average ticket price of $569.

How far in advance should I book a flight to Florida Keys?

You are more likely to see cheaper flights to Florida Keys from St. Louis when booking weeks ahead of your departure date. In general, you can expect to find flights to Florida Keys for around $398 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Florida Keys from St. Louis for as low as $324 on momondo.

Can stopping save me money on St. Louis to Florida Keys flights?

No. A direct flight is the cheapest option for a flight between St. Louis to Florida Keys.

Cheap St. Louis to Florida Keys flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from St. Louis to Florida Keys

Fastest flight time

2h 40m

Direct flights

Every day

Airports in Florida Keys

3 airports
The fastest flight from St. Louis to Florida Keys takes 2h 40m
Direct flights go from St. Louis to Florida Keys every day.
There are 3 airports in Florida Keys. From St. Louis there are direct flights to Miami (MIA).
Search flight deals

  • When did momondo last update prices for flights from Lambert-St Louis Airport to Florida Keys?

    Prices for flights from Lambert-St Louis Airport to Florida Keys were last updated today.

  • How many operators does momondo search for flights from Lambert-St Louis Airport to Florida Keys?

  • How old do you have to be to fly from Lambert-St Louis Airport to Florida Keys?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Lambert-St Louis Airport to Florida Keys.

  • What documentation or ID do you need to fly to Florida Keys?

    The required travel and health documents for your Florida Keys trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florida Keys. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from St. Louis to Florida Keys?

Best airlines flying from St. Louis to Florida Keys

Compare and see reviews for airlines that fly from St. Louis to Florida Keys with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $216Free CancellationRating
7.9
8,128 reviews
Search Delta flights
American AirlinesPriceFrom $222Free CancellationRating
7.2
11,205 reviews
Search American Airlines flights
United AirlinesPriceFrom $245Free CancellationRating
7.4
9,215 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from St. Louis to Florida Keys?

Finding the right flight to Florida Keys from St. Louis is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Florida Keys quick and easy, saving you time and money.

Can I find flights from St. Louis to Florida Keys with flexible booking policies on momondo?

Flights from St. Louis to Florida Keys with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from St. Louis to Florida Keys?

Once all potential St. Louis to Florida Keys flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from St. Louis to Florida Keys right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of St. Louis to Florida Keys flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Florida Keys trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Sat 2/28
Sat 3/7
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Florida Keys

Popular cities in Florida Keys

Popular flights according to clicks in the last 7 days on momondo
Flights to New Yorkfrom $38
Flights to Los Angelesfrom $31
Flights to Miamifrom $49
Flights to Chicagofrom $49
Flights to Orlandofrom $44
Flights to San Franciscofrom $73
Flights to Las Vegasfrom $53
Flights to Washington, D.C.from $49
Flights to Bostonfrom $52
Flights to Atlantafrom $44
Flights to Dallasfrom $54
Flights to Seattlefrom $56