Latest deals
Insights
FAQs
Reviews
Price Alerts

Cheap flights from St. Louis to Florida Keys from $64

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from St. Louis to Florida Keys departing on 1/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from St. Louis to Florida Keys

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
5:11 pm - 12:26 pm
STL
-
EYW
18h 15m1 stop
Multiple Airlines Logo
1:06 pm - 11:33 pm
EYW
-
STL
11h 27m1 stop
$185Multiple Airlines
Sun, Jan 18 - Fri, Jan 23
Multiple Airlines Logo
5:11 pm - 2:56 pm
STL
-
EYW
20h 45m1 stop
Multiple Airlines Logo
3:46 pm - 11:33 pm
EYW
-
STL
8h 47m1 stop
$186Multiple Airlines
Sat, Jan 17 - Thu, Jan 22
Multiple Airlines Logo
5:11 pm - 9:26 am
STL
-
EYW
15h 15m1 stop
Multiple Airlines Logo
10:06 am - 8:05 am
EYW
-
STL
22h 59m1 stop
$187Multiple Airlines
Wed, Jan 7 - Sun, Jan 11
Multiple Airlines Logo
5:11 pm - 9:26 am
STL
-
EYW
15h 15m1 stop
Multiple Airlines Logo
10:06 am - 9:21 am
EYW
-
STL
24h 15m1 stop
$199Multiple Airlines
Sat, Jan 17 - Sun, Jan 25
Multiple Airlines Logo
8:32 pm - 9:37 pm
STL
-
EYW
24h 05m2 stops
Multiple Airlines Logo
3:46 pm - 11:33 pm
EYW
-
STL
8h 47m1 stop
$206Multiple Airlines
Sat, Jan 17 - Thu, Jan 22
American Airlines Logo
6:00 am - 12:35 pm
STL
-
EYW
5h 35m1 stop
American Airlines Logo
2:04 pm - 10:44 pm
EYW
-
STL
9h 40m1 stop
$220American Airlines
Tue, Jan 20 - Sat, Jan 24
Frontier Logo
3:49 pm - 10:28 am
STL
-
MIA
17h 39m2 stops
Frontier Logo
7:09 pm - 6:51 am
MIA
-
STL
12h 42m1 stop
$238Frontier
Thu, Feb 19 - Sun, Mar 1
Frontier Logo
2:51 pm - 5:14 am
STL
-
MIA
13h 23m1 stop
Frontier Logo
6:25 am - 1:09 pm
MIA
-
STL
7h 44m1 stop
$240Frontier
Sat, Feb 21 - Fri, Feb 27
Frontier Logo
8:22 pm - 10:59 am
STL
-
MIA
13h 37m1 stop
Frontier Logo
3:09 pm - 6:51 am
MIA
-
STL
40h 42m2 stops
$242Frontier
Sat, Feb 7 - Sat, Feb 14
Frontier Logo
5:42 pm - 10:59 am
STL
-
MIA
16h 17m2 stops
Frontier Logo
7:09 pm - 6:51 am
MIA
-
STL
12h 42m1 stop
$247Frontier
Thu, Jan 22 - Sun, Jan 25

Frontier flights from St. Louis to Florida Keys

Our best Frontier deals on St. Louis to Florida Keys flight tickets
Frontier
Feb 28
STL3:49 pmLambert-St Louis
17h 34m
2 stops
MIA10:23 amMiami
Mar 8
MIA12:26 pmMiami
25h 53m
1 stop
STL1:19 pmLambert-St Louis
$235
Find similar
Frontier
Feb 21
STL2:51 pmLambert-St Louis
13h 23m
1 stop
MIA5:14 amMiami
Feb 27
MIA6:25 amMiami
7h 44m
1 stop
STL1:09 pmLambert-St Louis
$240
Find similar
Frontier
Feb 7
STL8:22 pmLambert-St Louis
13h 37m
1 stop
MIA10:59 amMiami
Feb 14
MIA3:09 pmMiami
40h 42m
2 stops
STL6:51 amLambert-St Louis
$242
Find similar

Southwest flights from St. Louis to Florida Keys

Our best Southwest deals on St. Louis to Florida Keys flight tickets
Southwest
Jan 24
STL5:45 pmLambert-St Louis
2h 40m
MIA9:25 pmMiami
Jan 31
MIA7:35 amMiami
3h 00m
STL9:35 amLambert-St Louis
$289
Find similar
Southwest
Jan 24
STL5:45 pmLambert-St Louis
2h 40m
MIA9:25 pmMiami
Jan 31
MIA7:00 amMiami
6h 50m
1 stop
STL12:50 pmLambert-St Louis
$299
Find similar
Southwest
Jan 7
STL8:15 amLambert-St Louis
2h 45m
MIA12:00 pmMiami
Jan 14
MIA4:55 pmMiami
3h 05m
STL7:00 pmLambert-St Louis
$301
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from St. Louis to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from St. Louis to Florida Keys that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Sun 1/18

5:11 pm-12:26 pm

1 stop18h 15m

Key West

Fri 1/23

1:06 pm-11:33 pm

1 stop11h 27m

$185

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Sat 1/17

5:11 pm-2:56 pm

1 stop20h 45m

Key West

Thu 1/22

3:46 pm-11:33 pm

1 stop8h 47m

$186

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Wed 1/7

5:11 pm-9:26 am

1 stop15h 15m

Key West

Sun 1/11

10:06 am-8:05 am

1 stop22h 59m

$187

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Sat 1/17

5:11 pm-9:26 am

1 stop15h 15m

Key West

Sun 1/25

10:06 am-9:21 am

1 stop24h 15m

$199

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Sat 1/17

8:32 pm-9:37 pm

2 stops24h 05m

Key West

Thu 1/22

3:46 pm-11:33 pm

1 stop8h 47m

$206

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Tue 1/20

6:00 am-12:35 pm

1 stop5h 35m

Key West

Sat 1/24

2:04 pm-10:44 pm

1 stop9h 40m

$220

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Thu 2/19

3:49 pm-10:28 am

2 stops17h 39m

Miami

Sun 3/1

7:09 pm-6:51 am

1 stop12h 42m

$238

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Sat 2/21

2:51 pm-5:14 am

1 stop13h 23m

Miami

Fri 2/27

6:25 am-1:09 pm

1 stop7h 44m

$240

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Sat 2/7

8:22 pm-10:59 am

1 stop13h 37m

Miami

Sat 2/14

3:09 pm-6:51 am

2 stops40h 42m

$242

St. LouisMiami

STL - MIA

STLMIA

Lambert-St Louis

Thu 1/22

5:42 pm-10:59 am

2 stops16h 17m

Miami

Sun 1/25

7:09 pm-6:51 am

1 stop12h 42m

$247

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Florida Keys from

How to get the cheapest flight ticket from St. Louis to Florida Keys

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Florida Keys?

The month of October is another great option to travel to Florida Keys, with average flight prices from St. Louis averaging around $329.

What is the cheapest day to depart on your flight to Florida Keys?

The cheapest day to depart from St. Louis to Florida Keys is on a Sunday when prices can be found for as low as $551. The most expensive day to fly to Florida Keys is Thursday, with ticket prices averaging around $591.

What is the cheapest time of day to depart on your flight to Florida Keys?

According to our data, the cheapest time of day to fly to Florida Keys is in the evening. momondo users have found flights departing from St. Louis to Florida Keys in the evening for as low as $440. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights in the morning are often more expensive with an average ticket price of $582.

How far in advance should I book a flight to Florida Keys?

You are more likely to see cheaper flights to Florida Keys from St. Louis when booking weeks ahead of your departure date. In general, you can expect to find flights to Florida Keys for around $401 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Florida Keys from St. Louis for as low as $319 on momondo.

Can stopping save me money on St. Louis to Florida Keys flights?

No. A direct flight is the cheapest option for a flight between St. Louis to Florida Keys.

Cheap St. Louis to Florida Keys flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from St. Louis to Florida Keys

Fastest flight time

2h 40m

Direct flights

Every day

Airports in Florida Keys

3 airports
The fastest flight from St. Louis to Florida Keys takes 2h 40m
Direct flights go from St. Louis to Florida Keys every day.
There are 3 airports in Florida Keys. From St. Louis there are direct flights to Miami (MIA).
Search flight deals

  • When did momondo last update prices for flights from Lambert-St Louis Airport to Florida Keys?

    Prices for flights from Lambert-St Louis Airport to Florida Keys were last updated today.

  • How many operators does momondo search for flights from Lambert-St Louis Airport to Florida Keys?

  • How old do you have to be to fly from Lambert-St Louis Airport to Florida Keys?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Lambert-St Louis Airport to Florida Keys.

  • What documentation or ID do you need to fly to Florida Keys?

    The required travel and health documents for your Florida Keys trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florida Keys. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from St. Louis to Florida Keys?

Best airlines flying from St. Louis to Florida Keys

Compare and see reviews for airlines that fly from St. Louis to Florida Keys with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $222Free CancellationRating
7.9
8,005 reviews
Search Delta flights
American AirlinesPriceFrom $227Free CancellationRating
7.2
11,054 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from St. Louis to Florida Keys?

Finding the right flight to Florida Keys from St. Louis is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Florida Keys quick and easy, saving you time and money.

Can I find flights from St. Louis to Florida Keys with flexible booking policies on momondo?

Flights from St. Louis to Florida Keys with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from St. Louis to Florida Keys?

Once all potential St. Louis to Florida Keys flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from St. Louis to Florida Keys right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of St. Louis to Florida Keys flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Florida Keys trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Sat 1/17
Sat 1/24
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Florida Keys

Popular cities in Florida Keys

Popular flights according to clicks in the last 7 days on momondo
Flights to New Yorkfrom $45
Flights to Los Angelesfrom $48
Flights to Miamifrom $49
Flights to Chicagofrom $58
Flights to Orlandofrom $40
Flights to San Franciscofrom $58
Flights to Las Vegasfrom $49
Flights to Washington, D.C.from $57
Flights to Bostonfrom $51
Flights to Atlantafrom $46
Flights to Dallasfrom $57
Flights to Seattlefrom $58