Cheap flights from Spain to Chicago from $358

The month of October is, on average, the cheapest month to fly to Chicago from Spain, with most prices found around $290. If you’re not able to fly to Chicago in October, then December is your next best option. Flight prices from Spain to Chicago during December average around $302.

The cheapest day to depart on your flight to Chicago is on a Friday when prices can be found for as low as $781. This is often the case because there is less demand to fly during this day of the week. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Spain to Chicago for around $1,188.

Our most recent data shows that the best time of day to fly to Chicago is in the morning. Flights from Spain to Chicago during this time can be as low as $734. In contrast, the most expensive time of day to depart to Chicago is in the afternoon when prices are around $918.

Fly from Madrid Barajas to Chicago O'Hare Intl for the best Spain - Chicago flight prices

You are more likely to see cheaper flights to Chicago from Spain when booking weeks ahead of your departure date. In general, you can expect to find flights to Chicago for around $703 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Chicago from Spain for as low as $599 on momondo.

There are 3 cabin classes available to choose from on Spain to Chicago flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Iberia, Aer Lingus, and American Airlines are the most popular carriers operating from Spain to Chicago

Iberia, British Airways and United Airlines are the top three most popular airlines that fly to Chicago from Spain according to our data. Iberia is the first choice among our users, with 51% of people opting to fly with this airline when traveling to Chicago. Keep in mind that there are 9 different airlines that fly to Chicago on a routine basis, so you have a few additional options to choose from.

Historically, on average around 14% of flights between Spain and Chicago have experienced a delay on any given week. The average delay length over the past 12 months has been 188 minutes.

Generally, flights departing in the morning tend to experience fewer delays. Flights in the early afternoon have, in the past, seen delays more frequently in comparison.

Saturday is statistically the day of the week which experiences the fewest number of delays on this flight route. Sunday has historically seen more delays on average compared to the rest of the week.

According to our data, American Airlines have had the least number of delays on this route over the last 12 months; with about 9% of their flights experiencing any sort of delay.

As of June 2026, 15 flights take off from Spain and land in Chicago each day. The most common flight departure time for this route is 10:00AM, with 53% of daily flights taking off at noon.

As of June 2026, 106 flights take off from Spain and land in Chicago each week. The most common flight departure day for this route is Fri, with 17% of weekly flights taking off on this day.