What airlines fly to Panama City, Florida?

American Airlines, United Airlines and Delta are the top three most popular airlines that fly to Panama City, Florida from South Dakota according to our data. American Airlines is the first choice among our users, with 68% of people opting to fly with this airline when traveling to Panama City, Florida. Keep in mind that there are 3 different airlines that fly to Panama City, Florida on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from South Dakota to Panama City NW Florida Beaches?

American Airlines, Delta, and United Airlines are the most popular carriers operating from South Dakota to Panama City NW Florida Beaches

How long does it take to fly to Panama City, Florida?

Flight times vary depending on what airport in South Dakota you fly out of and what airport in Panama City, Florida you fly into. For example, flying from Sioux Falls to Pensacola takes 4h 59m on average. On the other hand, flying from Rapid City to Pensacola takes 7h 09m on average. Keep in mind that it’s always quicker to opt for a non-stop flight, so be sure to check momondo if there are any available for your route.

When did momondo last update prices for flights from South Dakota to Panama City NW Florida Beaches Airport?

Prices for flights from South Dakota to Panama City NW Florida Beaches Airport were last updated today.

How many operators does momondo search for flights from South Dakota to Panama City NW Florida Beaches Airport?

There are 2 operators available for flights from South Dakota to Panama City NW Florida Beaches Airport as of September 2026.

How old do you have to be to fly from South Dakota to Panama City NW Florida Beaches Airport?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Dakota to Panama City NW Florida Beaches Airport.

What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

The required travel and health documents for your Panama City NW Florida Beaches Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City NW Florida Beaches Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$319 Cheap Flights from South Dakota to Panama City, Florida in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from South Dakota to Panama City

Round-trip

One-way

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Cheap round-trip flights

Enter your travel dates to find the best prices.

12:33 pm - 8:59 pmFSD Sioux Falls Joe Foss Field-ECP Panama City NW Florida Beaches

8h 26m1 stop Dallas/Fort Worth

1:06 pm - 7:05 pmECP Panama City NW Florida Beaches-FSD Sioux Falls Joe Foss Field

5h 59m1 stop Chicago O'Hare Intl

$321American Airlines

Tue, Feb 23 - Tue, Mar 2

12:33 pm - 8:59 pmFSD Sioux Falls Joe Foss Field-ECP Panama City NW Florida Beaches

8h 26m1 stop Dallas/Fort Worth

7:19 am - 7:05 pmECP Panama City NW Florida Beaches-FSD Sioux Falls Joe Foss Field

11h 46m2 stops Charlotte Douglas Chicago O'Hare Intl

$326American Airlines

Tue, Feb 23 - Tue, Mar 2

9:14 am - 9:43 pmFSD Sioux Falls Joe Foss Field-ECP Panama City NW Florida Beaches

12h 29m2 stops Denver Intl Houston George Bush Intcntl

2:08 pm - 10:23 pmECP Panama City NW Florida Beaches-FSD Sioux Falls Joe Foss Field

8h 15m1 stop Chicago O'Hare Intl

$326United Airlines

Wed, Jan 6 - Sat, Jan 9

10:00 am - 9:43 pmFSD Sioux Falls Joe Foss Field-ECP Panama City NW Florida Beaches

11h 43m2 stops Chicago O'Hare Intl Houston George Bush Intcntl

8:50 am - 8:46 pmECP Panama City NW Florida Beaches-FSD Sioux Falls Joe Foss Field

11h 56m2 stops Houston George Bush Intcntl Denver Intl

$331United Airlines

Wed, Jan 6 - Sat, Jan 9

6:00 am - 1:17 pmFSD Sioux Falls Joe Foss Field-ECP Panama City NW Florida Beaches

7h 17m1 stop Chicago O'Hare Intl

2:08 pm - 10:23 pmECP Panama City NW Florida Beaches-FSD Sioux Falls Joe Foss Field

8h 15m1 stop Chicago O'Hare Intl

$409United Airlines

Wed, Jan 6 - Sat, Jan 9

8:30 am - 4:37 pmFSD Sioux Falls Joe Foss Field-ECP Panama City NW Florida Beaches

8h 07m2 stops Minneapolis St Paul Atlanta Hartsfield-Jackson

12:30 pm - 7:55 pmECP Panama City NW Florida Beaches-FSD Sioux Falls Joe Foss Field

7h 25m1 stop Atlanta Hartsfield-Jackson

$482Delta

Wed, Oct 28 - Tue, Nov 3

8:30 am - 4:37 pmFSD Sioux Falls Joe Foss Field-ECP Panama City NW Florida Beaches

8h 07m2 stops Minneapolis St Paul Atlanta Hartsfield-Jackson

12:30 pm - 7:55 pmECP Panama City NW Florida Beaches-FSD Sioux Falls Joe Foss Field

7h 25m1 stop Atlanta Hartsfield-Jackson

$488Delta

Wed, Oct 28 - Sat, Oct 31

8:30 am - 11:18 pmFSD Sioux Falls Joe Foss Field-ECP Panama City NW Florida Beaches

14h 48m2 stops Minneapolis St Paul Atlanta Hartsfield-Jackson

12:30 pm - 7:55 pmECP Panama City NW Florida Beaches-FSD Sioux Falls Joe Foss Field

7h 25m1 stop Atlanta Hartsfield-Jackson

$545Delta

Tue, Oct 27 - Tue, Nov 3

12:51 pm - 9:17 pmRAP Rapid City-ECP Panama City NW Florida Beaches

7h 26m1 stop Dallas/Fort Worth

4:07 pm - 10:02 pmECP Panama City NW Florida Beaches-RAP Rapid City

6h 55m1 stop Dallas/Fort Worth

$641American Airlines

Fri, Oct 16 - Tue, Oct 20

12:51 pm - 9:17 pmRAP Rapid City-ECP Panama City NW Florida Beaches

7h 26m1 stop Dallas/Fort Worth

4:07 pm - 10:02 pmECP Panama City NW Florida Beaches-RAP Rapid City

6h 55m1 stop Dallas/Fort Worth

$666American Airlines

Fri, Oct 16 - Tue, Oct 20

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Delta flights from South Dakota to Panama City, Florida

Our best Delta deals on South Dakota to Panama City, Florida flight tickets

Delta

Oct 28

FSD8:30 amSioux Falls Joe Foss Field

8h 07m

2 stops

ECP4:37 pmPanama City NW Florida Beaches

Nov 3

ECP12:30 pmPanama City NW Florida Beaches

7h 25m

1 stop

FSD7:55 pmSioux Falls Joe Foss Field

$482

Delta

Oct 28

FSD8:30 amSioux Falls Joe Foss Field

8h 07m

2 stops

ECP4:37 pmPanama City NW Florida Beaches

Oct 31

ECP12:30 pmPanama City NW Florida Beaches

7h 25m

1 stop

FSD7:55 pmSioux Falls Joe Foss Field

$488

Delta

Oct 27

FSD8:30 amSioux Falls Joe Foss Field

14h 48m

2 stops

ECP11:18 pmPanama City NW Florida Beaches

Nov 3

ECP12:30 pmPanama City NW Florida Beaches

7h 25m

1 stop

FSD7:55 pmSioux Falls Joe Foss Field

$545

United Airlines flights from South Dakota to Panama City, Florida

Our best United Airlines deals on South Dakota to Panama City, Florida flight tickets

United Airlines

Jan 6

FSD6:00 amSioux Falls Joe Foss Field

7h 17m

1 stop

ECP1:17 pmPanama City NW Florida Beaches

Jan 9

ECP2:08 pmPanama City NW Florida Beaches

8h 15m

1 stop

FSD10:23 pmSioux Falls Joe Foss Field

$409

United Airlines

Jan 23

FSD6:00 amSioux Falls Joe Foss Field

7h 17m

1 stop

ECP1:17 pmPanama City NW Florida Beaches

Jan 27

ECP2:08 pmPanama City NW Florida Beaches

8h 15m

1 stop

FSD10:23 pmSioux Falls Joe Foss Field

$431

United Airlines

Jan 23

FSD6:00 amSioux Falls Joe Foss Field

7h 17m

1 stop

ECP1:17 pmPanama City NW Florida Beaches

Jan 27

ECP3:00 pmPanama City NW Florida Beaches

7h 56m

2 stops

FSD10:56 pmSioux Falls Joe Foss Field

$436

momondo Fare Finder

Use the filters below to find and compare flights from South Dakota to Panama City, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Sioux FallsPanama City

FSD Sioux Falls Joe Foss Field - ECP Panama City NW Florida Beaches

FSDECP

Sioux Falls Joe Foss Field

Tue 2/23

12:33 pm-8:59 pm

1 stop8h 26m

Panama City NW Florida Beaches

Tue 3/2

1:06 pm-7:05 pm

1 stop5h 59m

$321

Sioux FallsPanama City

FSD Sioux Falls Joe Foss Field - ECP Panama City NW Florida Beaches

FSDECP

Sioux Falls Joe Foss Field

Tue 2/23

12:33 pm-8:59 pm

1 stop8h 26m

Panama City NW Florida Beaches

Tue 3/2

7:19 am-7:05 pm

2 stops11h 46m

$326

Sioux FallsPanama City

FSD Sioux Falls Joe Foss Field - ECP Panama City NW Florida Beaches

FSDECP

Sioux Falls Joe Foss Field

Wed 1/6

9:14 am-9:43 pm

2 stops12h 29m

Panama City NW Florida Beaches

Sat 1/9

2:08 pm-10:23 pm

1 stop8h 15m

$326

Sioux FallsPanama City

FSD Sioux Falls Joe Foss Field - ECP Panama City NW Florida Beaches

FSDECP

Sioux Falls Joe Foss Field

Wed 1/6

10:00 am-9:43 pm

2 stops11h 43m

Panama City NW Florida Beaches

Sat 1/9

8:50 am-8:46 pm

2 stops11h 56m

$331

Sioux FallsPanama City

FSD Sioux Falls Joe Foss Field - ECP Panama City NW Florida Beaches

FSDECP

Sioux Falls Joe Foss Field

Wed 1/6

6:00 am-1:17 pm

1 stop7h 17m

Panama City NW Florida Beaches

Sat 1/9

2:08 pm-10:23 pm

1 stop8h 15m

$409

Sioux FallsPanama City

FSD Sioux Falls Joe Foss Field - ECP Panama City NW Florida Beaches

FSDECP

Sioux Falls Joe Foss Field

Wed 10/28

8:30 am-4:37 pm

2 stops8h 07m

Panama City NW Florida Beaches

Tue 11/3

12:30 pm-7:55 pm

1 stop7h 25m

$482

Sioux FallsPanama City

FSD Sioux Falls Joe Foss Field - ECP Panama City NW Florida Beaches

FSDECP

Sioux Falls Joe Foss Field

Wed 10/28

8:30 am-4:37 pm

2 stops8h 07m

Panama City NW Florida Beaches

Sat 10/31

12:30 pm-7:55 pm

1 stop7h 25m

$488

Sioux FallsPanama City

FSD Sioux Falls Joe Foss Field - ECP Panama City NW Florida Beaches

FSDECP

Sioux Falls Joe Foss Field

Tue 10/27

8:30 am-11:18 pm

2 stops14h 48m

Panama City NW Florida Beaches

Tue 11/3

12:30 pm-7:55 pm

1 stop7h 25m

$545

Quickest round-trip

Rapid CityPanama City

RAP Rapid City - ECP Panama City NW Florida Beaches

RAPECP

Rapid City

Fri 10/16

12:51 pm-9:17 pm

1 stop7h 26m

Panama City NW Florida Beaches

Tue 10/20

4:07 pm-10:02 pm

1 stop6h 55m

$641

Rapid CityPanama City

RAP Rapid City - ECP Panama City NW Florida Beaches

RAPECP

Rapid City

Fri 10/16

12:51 pm-9:17 pm

1 stop7h 26m

Panama City NW Florida Beaches

Tue 10/20

4:07 pm-10:02 pm

1 stop6h 55m

$666

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first

How to get the cheapest flight ticket from South Dakota to Panama City, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

Can stopping save me money on South Dakota to Panama City, Florida flights?

You could potentially save up to 3% on your flight if you consider stops on a South Dakota to Panama City, Florida flight.

Cheap South Dakota to Panama City, Florida flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Dakota to Panama City, Florida

Best Price Found	$319
Fastest flight time	5h 13m
Direct flights	None

The best one-way flight to Panama City, Florida from South Dakota in the past 72 hours is $319. The best round-trip flight deal from South Dakota to Panama City, Florida found on momondo in the last 72 hours is $321.

The fastest flight from South Dakota to Panama City, Florida takes 5h 13m

There are no direct flights from South Dakota to Panama City, Florida. There are no popular flight routes from South Dakota to Panama City, Florida.

Search flight deals

Frequently asked questions about flying from South Dakota to Panama City, Florida

When did momondo last update prices for flights from South Dakota to Panama City NW Florida Beaches Airport?
Prices for flights from South Dakota to Panama City NW Florida Beaches Airport were last updated today.
How many operators does momondo search for flights from South Dakota to Panama City NW Florida Beaches Airport?
There are 2 operators available for flights from South Dakota to Panama City NW Florida Beaches Airport as of September 2026.
How old do you have to be to fly from South Dakota to Panama City NW Florida Beaches Airport?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Dakota to Panama City NW Florida Beaches Airport.
What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?
The required travel and health documents for your Panama City NW Florida Beaches Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City NW Florida Beaches Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from South Dakota to Panama City, Florida

Compare and see reviews for airlines that fly from South Dakota to Panama City, Florida with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $279	Free Cancellation	Rating 7.0 12,097 reviews		Search American Airlines flights
Delta	PriceFrom $310	Free Cancellation	Rating 7.8 8,608 reviews		Search Delta flights

Panama City Beach

Rosemary Beach

Port St. Joe

Seaside

Mexico Beach

Seagrove Beach

Freeport

Why use momondo?

Why should I use momondo to find a flight deal from South Dakota to Panama City?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from South Dakota to Panama City for you.

Can I find flights from South Dakota to Panama City with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for South Dakota to Panama City flights to just show those with flexible booking policies.

How can momondo help me find flights from South Dakota to Panama City?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama City from South Dakota.

I’m not ready to book a flight from South Dakota to Panama City right now. Can momondo alert me if prices change?

Price alerts on flights to Panama City from South Dakota are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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Cheap flights from South Dakota to Panama City from $319

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Dakota to Panama City departing on 10/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Delta flights from South Dakota to Panama City, Florida

Our best Delta deals on South Dakota to Panama City, Florida flight tickets

United Airlines flights from South Dakota to Panama City, Florida

Our best United Airlines deals on South Dakota to Panama City, Florida flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from South Dakota to Panama City, Florida that are best for you.

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How to get the cheapest flight ticket from South Dakota to Panama City, Florida

Can stopping save me money on South Dakota to Panama City, Florida flights?

What is the cheapest airline that flies from South Dakota to Panama City NW Florida Beaches?

What airlines fly to Panama City, Florida?

How long does it take to fly to Panama City, Florida?

Cheap South Dakota to Panama City, Florida flight deals and tips

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Frequently asked questions about flying from South Dakota to Panama City, Florida

Best airlines flying from South Dakota to Panama City, Florida

Compare and see reviews for airlines that fly from South Dakota to Panama City, Florida with momondo

Traveling to a place near Panama City?

Why use momondo?

An easier way to manage your Panama City, Florida trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

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Find better results for your trip to the United States

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Airlines are sorted and displayed according to clicks in the past 7 days on momondo

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List of cabin classes available on flights landing in Panama City. Availability may vary depending on flight origin and airline.

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