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Cheap flights from South Dakota to Key West from $207

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Dakota to Key West departing on 5/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from South Dakota to Key West

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
12:14 pm - 10:22 pm
FSD
-
EYW
9h 08m
2 stops
American Airlines Logo
1:55 pm - 11:03 pm
EYW
-
FSD
10h 08m
2 stops
$319American Airlines
Wed, Feb 25 - Wed, Mar 4
American Airlines Logo
6:00 am - 4:30 pm
FSD
-
EYW
9h 30m
2 stops
American Airlines Logo
2:29 pm - 9:54 pm
EYW
-
FSD
8h 25m
1 stop
$341American Airlines
Tue, May 5 - Tue, May 12
American Airlines Logo
12:14 pm - 10:37 pm
FSD
-
EYW
9h 23m
2 stops
American Airlines Logo
1:55 pm - 11:03 pm
EYW
-
FSD
10h 08m
2 stops
$344American Airlines
Thu, Feb 19 - Wed, Feb 25
American Airlines Logo
12:14 pm - 10:22 pm
FSD
-
EYW
9h 08m
2 stops
American Airlines Logo
1:55 pm - 11:03 pm
EYW
-
FSD
10h 08m
2 stops
$346American Airlines
Wed, Feb 25 - Wed, Mar 4
American Airlines Logo
12:14 pm - 10:22 pm
FSD
-
EYW
9h 08m
2 stops
American Airlines Logo
1:55 pm - 11:03 pm
EYW
-
FSD
10h 08m
2 stops
$359American Airlines
Wed, Feb 25 - Wed, Mar 4
American Airlines Logo
12:14 pm - 10:18 pm
FSD
-
EYW
9h 04m
2 stops
American Airlines Logo
2:25 pm - 9:40 pm
EYW
-
FSD
8h 15m
1 stop
$374American Airlines
Tue, Mar 24 - Wed, Apr 1
Delta Logo
5:10 am - 1:44 pm
FSD
-
EYW
7h 34m
1 stop
Delta Logo
2:00 pm - 7:49 pm
EYW
-
FSD
6h 49m
1 stop
$375Delta
Tue, May 5 - Tue, May 12
American Airlines Logo
12:14 pm - 10:22 pm
FSD
-
EYW
9h 08m
2 stops
American Airlines Logo
1:55 pm - 11:03 pm
EYW
-
FSD
10h 08m
2 stops
$385American Airlines
Wed, Feb 18 - Tue, Feb 24
American Airlines Logo
12:14 pm - 10:22 pm
FSD
-
EYW
9h 08m
2 stops
American Airlines Logo
2:45 pm - 9:40 pm
EYW
-
FSD
7h 55m
1 stop
$387American Airlines
Wed, Feb 25 - Wed, Mar 4
Delta Logo
6:30 am - 5:30 pm
ABR
-
EYW
10h 00m
2 stops
Delta Logo
11:43 am - 9:34 pm
EYW
-
ABR
10h 51m
2 stops
$1,915Delta
Wed, Mar 11 - Sun, Mar 15

United Airlines flights from South Dakota to Key West

Our best United Airlines deals on South Dakota to Key West flight tickets
United Airlines
Mar 4
FSD7:40 amSioux Falls Joe Foss Field
6h 20m
1 stop
EYW3:00 pmKey West
Mar 11
EYW4:05 pmKey West
6h 57m
1 stop
FSD10:02 pmSioux Falls Joe Foss Field
$395
United Airlines
Mar 3
FSD7:40 amSioux Falls Joe Foss Field
6h 20m
1 stop
EYW3:00 pmKey West
Mar 10
EYW4:05 pmKey West
6h 57m
1 stop
FSD10:02 pmSioux Falls Joe Foss Field
$423
United Airlines
May 12
FSD7:30 amSioux Falls Joe Foss Field
6h 37m
1 stop
EYW3:07 pmKey West
May 16
EYW4:47 pmKey West
18h 57m
2 stops
FSD10:44 amSioux Falls Joe Foss Field
$461

American Airlines flights from South Dakota to Key West

Our best American Airlines deals on South Dakota to Key West flight tickets
American Airlines
Feb 25
FSD12:14 pmSioux Falls Joe Foss Field
9h 08m
2 stops
EYW10:22 pmKey West
Mar 4
EYW1:55 pmKey West
10h 08m
2 stops
FSD11:03 pmSioux Falls Joe Foss Field
$319
American Airlines
May 5
FSD6:00 amSioux Falls Joe Foss Field
9h 30m
2 stops
EYW4:30 pmKey West
May 12
EYW2:29 pmKey West
8h 25m
1 stop
FSD9:54 pmSioux Falls Joe Foss Field
$341
American Airlines
Feb 19
FSD12:14 pmSioux Falls Joe Foss Field
9h 23m
2 stops
EYW10:37 pmKey West
Feb 25
EYW1:55 pmKey West
10h 08m
2 stops
FSD11:03 pmSioux Falls Joe Foss Field
$344

momondo Fare Finder

 
Customize your flight search to find flights from South Dakota to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 5, 2026.
Use the filters below to find and compare flights from South Dakota to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Wed 2/25

12:14 pm-10:22 pm

2 stops9h 08m

Key West

Wed 3/4

1:55 pm-11:03 pm

2 stops10h 08m

$319

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Tue 5/5

6:00 am-4:30 pm

2 stops9h 30m

Key West

Tue 5/12

2:29 pm-9:54 pm

1 stop8h 25m

$341

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Thu 2/19

12:14 pm-10:37 pm

2 stops9h 23m

Key West

Wed 2/25

1:55 pm-11:03 pm

2 stops10h 08m

$344

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Wed 2/25

12:14 pm-10:22 pm

2 stops9h 08m

Key West

Wed 3/4

1:55 pm-11:03 pm

2 stops10h 08m

$346

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Wed 2/25

12:14 pm-10:22 pm

2 stops9h 08m

Key West

Wed 3/4

1:55 pm-11:03 pm

2 stops10h 08m

$359

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Tue 3/24

12:14 pm-10:18 pm

2 stops9h 04m

Key West

Wed 4/1

2:25 pm-9:40 pm

1 stop8h 15m

$374

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Tue 5/5

5:10 am-1:44 pm

1 stop7h 34m

Key West

Tue 5/12

2:00 pm-7:49 pm

1 stop6h 49m

$375

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Wed 2/18

12:14 pm-10:22 pm

2 stops9h 08m

Key West

Tue 2/24

1:55 pm-11:03 pm

2 stops10h 08m

$385

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Wed 2/25

12:14 pm-10:22 pm

2 stops9h 08m

Key West

Wed 3/4

2:45 pm-9:40 pm

1 stop7h 55m

$387

AberdeenKey West

ABR - EYW

ABREYW

Aberdeen

Wed 3/11

6:30 am-5:30 pm

2 stops10h 00m

Key West

Sun 3/15

11:43 am-9:34 pm

2 stops10h 51m

$1,915

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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See travel insights to Key West from

How to get the cheapest flight ticket from South Dakota to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on South Dakota to Key West flights?

You could potentially save up to 25% on your flight if you consider stops on a South Dakota to Key West flight.

Cheap South Dakota to Key West flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Dakota to Key West

Fastest flight time

5h 54m

Direct flights

None
The fastest flight from South Dakota to Key West takes 5h 54m
There are no direct flights from South Dakota to Key West. There are no popular flight routes from South Dakota to Key West.
Search flight deals

  • When did momondo last update prices for flights from South Dakota to Key West Airport?

    Prices for flights from South Dakota to Key West Airport are updated daily.

  • How many operators does momondo search for flights from South Dakota to Key West Airport?

  • How old do you have to be to fly from South Dakota to Key West Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Dakota to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The travel and health documents required for your trip to Key West Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Key West Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from South Dakota to Key West

Compare and see reviews for airlines that fly from South Dakota to Key West with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $288Free CancellationRating
7.2
11,237 reviews
Search American Airlines flights
United AirlinesPriceFrom $381Free CancellationRating
7.4
9,240 reviews
Search United Airlines flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from South Dakota to Key West?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from South Dakota to Key West. momondo saves you time and could save you money on your trip.

Can I find flights from South Dakota to Key West with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for South Dakota to Key West flights to just show those with flexible booking policies.

How can momondo help me find flights from South Dakota to Key West?

Once you have performed a search for South Dakota to Key West flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from South Dakota to Key West right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Key West from South Dakota. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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