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Cheap flights from South Dakota to Key West from $282

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Dakota to Key West departing on 5/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from South Dakota to Key West

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
10:45 am - 11:04 am
FSD
-
EYW
23h 19m
1 stop
Multiple Airlines Logo
1:57 pm - 5:48 pm
EYW
-
FSD
28h 51m
2 stops
$303Multiple Airlines
Fri, May 8 - Thu, May 14
Multiple Airlines Logo
10:45 am - 11:04 am
FSD
-
EYW
23h 19m
1 stop
Multiple Airlines Logo
11:04 am - 9:55 am
EYW
-
FSD
23h 51m
1 stop
$318Multiple Airlines
Fri, May 8 - Thu, May 14
American Airlines Logo
12:29 pm - 10:36 pm
FSD
-
EYW
9h 07m
2 stops
American Airlines Logo
6:45 am - 2:47 pm
EYW
-
FSD
9h 02m
2 stops
$333American Airlines
Sat, May 2 - Wed, May 6
American Airlines Logo
12:29 pm - 10:36 pm
FSD
-
EYW
9h 07m
2 stops
American Airlines Logo
6:45 am - 2:47 pm
EYW
-
FSD
9h 02m
2 stops
$356American Airlines
Fri, May 1 - Wed, May 6
Multiple Airlines Logo
7:02 pm - 2:01 pm
FSD
-
EYW
17h 59m
1 stop
Multiple Airlines Logo
12:05 pm - 9:07 am
EYW
-
FSD
22h 02m
2 stops
$364Multiple Airlines
Sun, May 31 - Thu, Jun 4
American Airlines Logo
1:41 pm - 10:58 pm
FSD
-
EYW
8h 17m
2 stops
American Airlines Logo
11:56 am - 7:09 pm
EYW
-
FSD
8h 13m
2 stops
$379American Airlines
Fri, May 8 - Thu, May 14
Multiple Airlines Logo
10:45 am - 11:04 am
FSD
-
EYW
23h 19m
1 stop
Multiple Airlines Logo
5:48 pm - 10:45 am
EYW
-
FSD
41h 57m
2 stops
$390Multiple Airlines
Fri, May 1 - Fri, May 8
Multiple Airlines Logo
6:11 pm - 11:30 am
FSD
-
EYW
16h 19m
1 stop
Multiple Airlines Logo
11:01 am - 10:45 am
EYW
-
FSD
48h 44m
2 stops
$395Multiple Airlines
Mon, Apr 13 - Fri, Apr 17
American Airlines Logo
12:29 pm - 10:36 pm
FSD
-
EYW
9h 07m
2 stops
American Airlines Logo
11:56 am - 9:54 pm
EYW
-
FSD
10h 58m
2 stops
$411American Airlines
Fri, May 1 - Fri, May 8
American Airlines Logo
12:29 pm - 10:36 pm
FSD
-
EYW
9h 07m
2 stops
American Airlines Logo
2:29 pm - 9:54 pm
EYW
-
FSD
8h 25m
1 stop
$414American Airlines
Sat, May 2 - Wed, May 6

American Airlines flights from South Dakota to Key West

Our best American Airlines deals on South Dakota to Key West flight tickets
American Airlines
May 2
FSD12:29 pmSioux Falls Joe Foss Field
9h 07m
2 stops
EYW10:36 pmKey West
May 6
EYW6:45 amKey West
9h 02m
2 stops
FSD2:47 pmSioux Falls Joe Foss Field
$333
American Airlines
May 1
FSD12:29 pmSioux Falls Joe Foss Field
9h 07m
2 stops
EYW10:36 pmKey West
May 6
EYW6:45 amKey West
9h 02m
2 stops
FSD2:47 pmSioux Falls Joe Foss Field
$356
American Airlines
May 8
FSD1:41 pmSioux Falls Joe Foss Field
8h 17m
2 stops
EYW10:58 pmKey West
May 14
EYW11:56 amKey West
8h 13m
2 stops
FSD7:09 pmSioux Falls Joe Foss Field
$379

Delta flights from South Dakota to Key West

Our best Delta deals on South Dakota to Key West flight tickets
Delta
Apr 11
FSD9:50 amSioux Falls Joe Foss Field
8h 51m
2 stops
EYW7:41 pmKey West
Apr 15
EYW6:23 pmKey West
6h 17m
1 stop
FSD11:40 pmSioux Falls Joe Foss Field
$424
Delta
Jun 15
FSD5:15 amSioux Falls Joe Foss Field
7h 13m
1 stop
EYW1:28 pmKey West
Jun 20
EYW1:08 pmKey West
7h 51m
1 stop
FSD7:59 pmSioux Falls Joe Foss Field
$563
Delta
Sep 19
FSD5:25 amSioux Falls Joe Foss Field
6h 44m
1 stop
EYW1:09 pmKey West
Sep 22
EYW2:35 pmKey West
8h 34m
1 stop
FSD10:09 pmSioux Falls Joe Foss Field
$617

momondo Fare Finder

 
Customize your flight search to find flights from South Dakota to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 31, 2026.
Use the filters below to find and compare flights from South Dakota to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Fri 5/8

10:45 am-11:04 am

1 stop23h 19m

Key West

Thu 5/14

1:57 pm-5:48 pm

2 stops28h 51m

$303

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Fri 5/8

10:45 am-11:04 am

1 stop23h 19m

Key West

Thu 5/14

11:04 am-9:55 am

1 stop23h 51m

$318

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Sat 5/2

12:29 pm-10:36 pm

2 stops9h 07m

Key West

Wed 5/6

6:45 am-2:47 pm

2 stops9h 02m

$333

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Fri 5/1

12:29 pm-10:36 pm

2 stops9h 07m

Key West

Wed 5/6

6:45 am-2:47 pm

2 stops9h 02m

$356

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Sun 5/31

7:02 pm-2:01 pm

1 stop17h 59m

Key West

Thu 6/4

12:05 pm-9:07 am

2 stops22h 02m

$364
Quickest round-trip

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Fri 5/8

1:41 pm-10:58 pm

2 stops8h 17m

Key West

Thu 5/14

11:56 am-7:09 pm

2 stops8h 13m

$379

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Fri 5/1

10:45 am-11:04 am

1 stop23h 19m

Key West

Fri 5/8

5:48 pm-10:45 am

2 stops41h 57m

$390

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Mon 4/13

6:11 pm-11:30 am

1 stop16h 19m

Key West

Fri 4/17

11:01 am-10:45 am

2 stops48h 44m

$395

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Fri 5/1

12:29 pm-10:36 pm

2 stops9h 07m

Key West

Fri 5/8

11:56 am-9:54 pm

2 stops10h 58m

$411

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Sat 5/2

12:29 pm-10:36 pm

2 stops9h 07m

Key West

Wed 5/6

2:29 pm-9:54 pm

1 stop8h 25m

$414

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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See travel insights to Key West from

How to get the cheapest flight ticket from South Dakota to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on South Dakota to Key West flights?

You could potentially save up to 17% on your flight if you consider stops on a South Dakota to Key West flight.

Cheap South Dakota to Key West flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Dakota to Key West

Fastest flight time

6h 12m

Direct flights

None
The fastest flight from South Dakota to Key West takes 6h 12m
There are no direct flights from South Dakota to Key West. There are no popular flight routes from South Dakota to Key West.
Search flight deals

  • When did momondo last update prices for flights from South Dakota to Key West Airport?

    Prices for flights from South Dakota to Key West Airport are updated daily.

  • How many operators does momondo search for flights from South Dakota to Key West Airport?

  • How old do you have to be to fly from South Dakota to Key West Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Dakota to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The travel and health documents required for your trip to Key West Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Key West Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from South Dakota to Key West

Compare and see reviews for airlines that fly from South Dakota to Key West with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $288Free CancellationRating
7.1
11,543 reviews
Search American Airlines flights
United AirlinesPriceFrom $490Free CancellationRating
7.4
9,525 reviews
Search United Airlines flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from South Dakota to Key West?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from South Dakota to Key West. momondo saves you time and could save you money on your trip.

Can I find flights from South Dakota to Key West with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for South Dakota to Key West flights to just show those with flexible booking policies.

How can momondo help me find flights from South Dakota to Key West?

Once you have performed a search for South Dakota to Key West flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from South Dakota to Key West right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Key West from South Dakota. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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