How many flights depart from South Carolina to Panama City, Florida on average per week?

As of September 2026, 6 flights take off from South Carolina and land in Panama City, Florida each week. The most common flight departure day for this route is Mon, with 50% of weekly flights taking off on this day.

What is the cheapest airline that flies from South Carolina to Panama City NW Florida Beaches?

Delta, Southwest, and American Airlines are the most popular carriers operating from South Carolina to Panama City NW Florida Beaches

What airlines fly to Panama City, Florida?

Delta, American Airlines and Southwest are the top three most popular airlines that fly to Panama City, Florida from South Carolina according to our data. Delta is the first choice among our users, with 73% of people opting to fly with this airline when traveling to Panama City, Florida. Keep in mind that there are 3 different airlines that fly to Panama City, Florida on a routine basis, so you have a few additional options to choose from.

How long does it take to fly to Panama City, Florida?

Flight times vary depending on what airport in South Carolina you fly out of and what airport in Panama City, Florida you fly into. For example, flying from Greenville to Pensacola takes 3h 21m on average. On the other hand, flying from Columbia to Pensacola takes 3h 39m on average. Keep in mind that it’s always quicker to opt for a non-stop flight, so be sure to check momondo if there are any available for your route.

When did momondo last update prices for flights from South Carolina to Panama City NW Florida Beaches Airport?

Prices for flights from South Carolina to Panama City NW Florida Beaches Airport refresh daily.

How many operators does momondo search for flights from South Carolina to Panama City NW Florida Beaches Airport?

There are 3 operators available for flights from South Carolina to Panama City NW Florida Beaches Airport as of September 2026.

How old do you have to be to fly from South Carolina to Panama City NW Florida Beaches Airport?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to Panama City NW Florida Beaches Airport.

What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

The necessary travel and health documents for your Panama City NW Florida Beaches Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$140 Cheap Flights from South Carolina to Panama City, Florida in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from South Carolina to Panama City

Round-trip

One-way

Last minute

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Cheap round-trip flights

Enter your travel dates to find the best prices.

5:40 am - 8:09 amGSP Greenville-ECP Panama City NW Florida Beaches

3h 29m1 stop Atlanta Hartsfield-Jackson

6:20 pm - 10:51 pmECP Panama City NW Florida Beaches-GSP Greenville

3h 31m1 stop Atlanta Hartsfield-Jackson

$312Delta

Fri, Oct 16 - Mon, Oct 19

7:25 pm - 10:40 pmGSP Greenville-ECP Panama City NW Florida Beaches

4h 15m1 stop Charlotte Douglas

6:42 pm - 11:21 pmECP Panama City NW Florida Beaches-GSP Greenville

3h 39m1 stop Charlotte Douglas

$312American Airlines

Tue, Oct 27 - Fri, Oct 30

7:00 am - 9:30 amGSP Greenville-ECP Panama City NW Florida Beaches

3h 30m1 stop Nashville Intl

1:50 pm - 10:50 pmECP Panama City NW Florida Beaches-GSP Greenville

8h 00m2 stops Austin Bergstrom Nashville Intl

$317Southwest

Tue, Oct 27 - Fri, Oct 30

8:35 pm - 11:48 pmGSP Greenville-ECP Panama City NW Florida Beaches

4h 13m1 stop Charlotte Douglas

7:01 pm - 11:27 pmECP Panama City NW Florida Beaches-GSP Greenville

3h 26m1 stop Charlotte Douglas

$318American Airlines

Thu, Nov 12 - Sun, Nov 15

8:30 am - 5:20 pmGSP Greenville-ECP Panama City NW Florida Beaches

9h 50m2 stops Baltimore/Washington Austin Bergstrom

3:10 pm - 10:50 pmECP Panama City NW Florida Beaches-GSP Greenville

6h 40m2 stops Houston Hobby Nashville Intl

$322Southwest

Tue, Oct 27 - Fri, Oct 30

5:45 am - 8:16 amGSP Greenville-ECP Panama City NW Florida Beaches

3h 31m1 stop Atlanta Hartsfield-Jackson

6:00 am - 1:00 pmECP Panama City NW Florida Beaches-GSP Greenville

6h 00m1 stop Atlanta Hartsfield-Jackson

$328Delta

Mon, Oct 5 - Sun, Oct 11

7:29 pm - 10:40 pmMYR Myrtle Beach Intl-ECP Panama City NW Florida Beaches

4h 11m1 stop Charlotte Douglas

8:05 am - 1:38 pmECP Panama City NW Florida Beaches-MYR Myrtle Beach Intl

4h 33m1 stop Charlotte Douglas

$339American Airlines

Tue, Oct 13 - Tue, Oct 20

5:12 pm - 9:36 pmGSP Greenville-ECP Panama City NW Florida Beaches

5h 24m1 stop Houston George Bush Intcntl

9:06 am - 3:14 pmECP Panama City NW Florida Beaches-GSP Greenville

5h 08m1 stop Houston George Bush Intcntl

$349United Airlines

Tue, Oct 27 - Sat, Oct 31

6:15 am - 1:17 pmCAE Columbia Metropolitan-ECP Panama City NW Florida Beaches

8h 02m1 stop Chicago O'Hare Intl

2:08 pm - 9:03 pmECP Panama City NW Florida Beaches-CAE Columbia Metropolitan

5h 55m1 stop Chicago O'Hare Intl

$369United Airlines

Sat, Jan 30 - Wed, Feb 3

7:14 pm - 11:18 pmGSP Greenville-ECP Panama City NW Florida Beaches

5h 04m1 stop Atlanta Hartsfield-Jackson

6:20 pm - 10:51 pmECP Panama City NW Florida Beaches-GSP Greenville

3h 31m1 stop Atlanta Hartsfield-Jackson

$377Delta

Mon, Oct 12 - Mon, Oct 19

Cheap last minute flights

Enter your travel dates to find the best prices.

10:45 am - 11:32 amCLT Charlotte Douglas-ECP Panama City NW Florida Beaches

1h 47mnonstop

1:32 pm - 4:16 pmECP Panama City NW Florida Beaches-CLT Charlotte Douglas

1h 44mnonstop

$495American Airlines

Tue, Sep 15 - Mon, Sep 28

5:02 pm - 7:08 pmCLT Charlotte Douglas-ECP Panama City NW Florida Beaches

3h 06m1 stop Atlanta Hartsfield-Jackson

7:35 am - 1:30 pmECP Panama City NW Florida Beaches-CLT Charlotte Douglas

4h 55m1 stop Atlanta Hartsfield-Jackson

$515Delta

Tue, Sep 15 - Mon, Sep 28

12:35 pm - 6:50 pmCLT Charlotte Douglas-ECP Panama City NW Florida Beaches

7h 15m1 stop Dallas Love Field

4:10 pm - 9:55 pmECP Panama City NW Florida Beaches-CLT Charlotte Douglas

4h 45m1 stop Nashville Intl

$515Southwest

Tue, Sep 15 - Thu, Sep 17

8:30 am - 6:15 pmCLT Charlotte Douglas-ECP Panama City NW Florida Beaches

10h 45m2 stops Baltimore/Washington Nashville Intl

1:30 pm - 6:40 pmECP Panama City NW Florida Beaches-CLT Charlotte Douglas

4h 10m1 stop Nashville Intl

$520Southwest

Tue, Sep 15 - Thu, Sep 17

2:25 pm - 7:08 pmCLT Charlotte Douglas-ECP Panama City NW Florida Beaches

5h 43m1 stop Atlanta Hartsfield-Jackson

6:00 am - 10:12 amECP Panama City NW Florida Beaches-CLT Charlotte Douglas

3h 12m1 stop Atlanta Hartsfield-Jackson

$535Delta

Fri, Sep 11 - Sat, Sep 12

6:00 am - 8:16 amCLT Charlotte Douglas-ECP Panama City NW Florida Beaches

3h 16m1 stop Atlanta Hartsfield-Jackson

7:35 am - 1:30 pmECP Panama City NW Florida Beaches-CLT Charlotte Douglas

4h 55m1 stop Atlanta Hartsfield-Jackson

$535Delta

Thu, Sep 10 - Sat, Sep 12

4:50 pm - 5:32 pmCLT Charlotte Douglas-ECP Panama City NW Florida Beaches

1h 42mnonstop

8:29 am - 11:20 amECP Panama City NW Florida Beaches-CLT Charlotte Douglas

1h 51mnonstop

$541American Airlines

Fri, Sep 11 - Mon, Sep 14

4:50 pm - 5:32 pmCLT Charlotte Douglas-ECP Panama City NW Florida Beaches

1h 42mnonstop

1:32 pm - 4:16 pmECP Panama City NW Florida Beaches-CLT Charlotte Douglas

1h 44mnonstop

$541American Airlines

Fri, Sep 11 - Mon, Sep 14

5:45 am - 1:13 pmCHS Charleston-ECP Panama City NW Florida Beaches

32h 28m3 stops Washington, D.C. Dulles Intl South Bend/Michiana Chicago O'Hare Intl

4:14 pm - 10:03 amECP Panama City NW Florida Beaches-CHS Charleston

16h 49m2 stops Chicago O'Hare Intl Washington, D.C. Reagan-National

$1,084United Airlines

Sun, Sep 13 - Fri, Sep 18

6:25 am - 1:13 pmCAE Columbia Metropolitan-ECP Panama City NW Florida Beaches

7h 48m1 stop Chicago O'Hare Intl

4:14 pm - 7:07 pmECP Panama City NW Florida Beaches-CAE Columbia Metropolitan

25h 53m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

$1,189United Airlines

Tue, Sep 15 - Thu, Sep 17

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United Airlines flights from South Carolina to Panama City, Florida

Our best United Airlines deals on South Carolina to Panama City, Florida flight tickets

United Airlines

Oct 27

GSP5:12 pmGreenville

5h 24m

1 stop

ECP9:36 pmPanama City NW Florida Beaches

Oct 31

ECP9:06 amPanama City NW Florida Beaches

5h 08m

1 stop

GSP3:14 pmGreenville

$349

United Airlines

Jan 30

CAE6:15 amColumbia Metropolitan

8h 02m

1 stop

ECP1:17 pmPanama City NW Florida Beaches

Feb 3

ECP2:08 pmPanama City NW Florida Beaches

5h 55m

1 stop

CAE9:03 pmColumbia Metropolitan

$369

United Airlines

Jan 30

CAE6:15 amColumbia Metropolitan

8h 02m

1 stop

ECP1:17 pmPanama City NW Florida Beaches

Feb 3

ECP2:08 pmPanama City NW Florida Beaches

5h 55m

1 stop

CAE9:03 pmColumbia Metropolitan

$389

American Airlines flights from South Carolina to Panama City, Florida

Our best American Airlines deals on South Carolina to Panama City, Florida flight tickets

American Airlines

Nov 12

GSP8:35 pmGreenville

4h 13m

1 stop

ECP11:48 pmPanama City NW Florida Beaches

Nov 15

ECP7:01 pmPanama City NW Florida Beaches

3h 26m

1 stop

GSP11:27 pmGreenville

$318

American Airlines

Oct 13

MYR7:29 pmMyrtle Beach Intl

4h 11m

1 stop

ECP10:40 pmPanama City NW Florida Beaches

Oct 20

ECP8:05 amPanama City NW Florida Beaches

4h 33m

1 stop

MYR1:38 pmMyrtle Beach Intl

$339

American Airlines

Oct 16

CHS8:08 pmCharleston

4h 45m

1 stop

ECP11:53 pmPanama City NW Florida Beaches

Oct 19

ECP6:42 pmPanama City NW Florida Beaches

4h 23m

1 stop

CHS12:05 amCharleston

$354

momondo Fare Finder

Use the filters below to find and compare flights from South Carolina to Panama City, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Quickest round-trip

GreenvillePanama City

GSP Greenville - ECP Panama City NW Florida Beaches

GSPECP

Greenville

Fri 10/16

5:40 am-8:09 am

1 stop3h 29m

Panama City NW Florida Beaches

Mon 10/19

6:20 pm-10:51 pm

1 stop3h 31m

$312

GreenvillePanama City

GSP Greenville - ECP Panama City NW Florida Beaches

GSPECP

Greenville

Tue 10/27

7:25 pm-10:40 pm

1 stop4h 15m

Panama City NW Florida Beaches

Fri 10/30

6:42 pm-11:21 pm

1 stop3h 39m

$312

GreenvillePanama City

GSP Greenville - ECP Panama City NW Florida Beaches

GSPECP

Greenville

Tue 10/27

7:00 am-9:30 am

1 stop3h 30m

Panama City NW Florida Beaches

Fri 10/30

1:50 pm-10:50 pm

2 stops8h 00m

$317

GreenvillePanama City

GSP Greenville - ECP Panama City NW Florida Beaches

GSPECP

Greenville

Thu 11/12

8:35 pm-11:48 pm

1 stop4h 13m

Panama City NW Florida Beaches

Sun 11/15

7:01 pm-11:27 pm

1 stop3h 26m

$318

GreenvillePanama City

GSP Greenville - ECP Panama City NW Florida Beaches

GSPECP

Greenville

Tue 10/27

8:30 am-5:20 pm

2 stops9h 50m

Panama City NW Florida Beaches

Fri 10/30

3:10 pm-10:50 pm

2 stops6h 40m

$322

GreenvillePanama City

GSP Greenville - ECP Panama City NW Florida Beaches

GSPECP

Greenville

Mon 10/5

5:45 am-8:16 am

1 stop3h 31m

Panama City NW Florida Beaches

Sun 10/11

6:00 am-1:00 pm

1 stop6h 00m

$328

Myrtle BeachPanama City

MYR Myrtle Beach Intl - ECP Panama City NW Florida Beaches

MYRECP

Myrtle Beach Intl

Tue 10/13

7:29 pm-10:40 pm

1 stop4h 11m

Panama City NW Florida Beaches

Tue 10/20

8:05 am-1:38 pm

1 stop4h 33m

$339

GreenvillePanama City

GSP Greenville - ECP Panama City NW Florida Beaches

GSPECP

Greenville

Tue 10/27

5:12 pm-9:36 pm

1 stop5h 24m

Panama City NW Florida Beaches

Sat 10/31

9:06 am-3:14 pm

1 stop5h 08m

$349

ColumbiaPanama City

CAE Columbia Metropolitan - ECP Panama City NW Florida Beaches

CAEECP

Columbia Metropolitan

Sat 1/30

6:15 am-1:17 pm

1 stop8h 02m

Panama City NW Florida Beaches

Wed 2/3

2:08 pm-9:03 pm

1 stop5h 55m

$369

GreenvillePanama City

GSP Greenville - ECP Panama City NW Florida Beaches

GSPECP

Greenville

Mon 10/12

7:14 pm-11:18 pm

1 stop5h 04m

Panama City NW Florida Beaches

Mon 10/19

6:20 pm-10:51 pm

1 stop3h 31m

$377

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from South Carolina to Panama City, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Panama City, Florida?

The cheapest month to fly to Panama City, Florida from South Carolina is in February. Flight prices, which tend to average around $328, are often lower during this time because this is during the off-season. The month of January is another great option to travel to Panama City, Florida, with average flight prices from South Carolina averaging around $361.

Cheap South Carolina to Panama City, Florida flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Panama City, Florida

Best Price Found	$140
Fastest flight time	3h 26m
Direct flights	Every day
Airports in Panama City, Florida	1 airport

The best one-way flight to Panama City, Florida from South Carolina in the past 72 hours is $140. The best round-trip flight deal from South Carolina to Panama City, Florida found on momondo in the last 72 hours is $312.

The fastest flight from South Carolina to Panama City, Florida takes 3h 26m

Direct flights go from South Carolina to Panama City, Florida every day.

There is 1 airport in Panama City, Florida. From South Carolina there are direct flights to Panama City NW Florida Beaches (ECP).

Search flight deals

Frequently asked questions about flying from South Carolina to Panama City, Florida

When did momondo last update prices for flights from South Carolina to Panama City NW Florida Beaches Airport?
Prices for flights from South Carolina to Panama City NW Florida Beaches Airport refresh daily.
How many operators does momondo search for flights from South Carolina to Panama City NW Florida Beaches Airport?
There are 3 operators available for flights from South Carolina to Panama City NW Florida Beaches Airport as of September 2026.
How old do you have to be to fly from South Carolina to Panama City NW Florida Beaches Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to Panama City NW Florida Beaches Airport.
What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?
The necessary travel and health documents for your Panama City NW Florida Beaches Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from South Carolina to Panama City, Florida

Compare and see reviews for airlines that fly from South Carolina to Panama City, Florida with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $264	Free Cancellation	Rating 7.1 12,046 reviews	Search American Airlines flights
Delta	PriceFrom $272	Free Cancellation	Rating 7.8 8,554 reviews	Search Delta flights
Southwest	PriceFrom $283	Free Cancellation	Rating 8.0 4,195 reviews	Search Southwest flights

Panama City Beach

Rosemary Beach

Port St. Joe

Seaside

Mexico Beach

Seagrove Beach

Freeport

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Panama City?

It is quick and easy to find South Carolina to Panama City flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Panama City that suits you.

Can I find flights from South Carolina to Panama City with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for South Carolina to Panama City flights to just show those with flexible booking policies.

How can momondo help me find flights from South Carolina to Panama City?

momondo helps you find the best flight between South Carolina and Panama City by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from South Carolina to Panama City right now. Can momondo alert me if prices change?

If you are not ready to book a flight from South Carolina to Panama City now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama City and let you know when they change.

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Cheap flights from South Carolina to Panama City from $140

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Panama City departing on 10/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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United Airlines flights from South Carolina to Panama City, Florida

Our best United Airlines deals on South Carolina to Panama City, Florida flight tickets

American Airlines flights from South Carolina to Panama City, Florida

Our best American Airlines deals on South Carolina to Panama City, Florida flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from South Carolina to Panama City, Florida that are best for you.

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How to get the cheapest flight ticket from South Carolina to Panama City, Florida

What is the cheapest month to fly to Panama City, Florida?

What is the cheapest airline that flies from South Carolina to Panama City NW Florida Beaches?

What airlines fly to Panama City, Florida?

How many flights depart from South Carolina to Panama City, Florida on average per week?

How long does it take to fly to Panama City, Florida?

Cheap South Carolina to Panama City, Florida flight deals and tips

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Airports in Panama City, Florida

Frequently asked questions about flying from South Carolina to Panama City, Florida

Best airlines flying from South Carolina to Panama City, Florida

Compare and see reviews for airlines that fly from South Carolina to Panama City, Florida with momondo

Traveling to a place near Panama City?

Why use momondo?

An easier way to manage your Panama City, Florida trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

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Airlines are sorted and displayed according to clicks in the past 7 days on momondo

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List of cabin classes available on flights landing in Panama City. Availability may vary depending on flight origin and airline.

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