Cheap flights from South Carolina to Ohio from $53

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Ohio departing on 3/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
10:13 am - 12:43 am
CLT
-
CLE
14h 30m
1 stop
Multiple Airlines Logo
8:25 pm - 7:14 pm
CLE
-
CLT
22h 49m
1 stop
$130Multiple Airlines
Tue, Apr 14 - Tue, Apr 21
Multiple Airlines Logo
10:13 am - 12:43 am
CLT
-
CLE
14h 30m
1 stop
Multiple Airlines Logo
8:25 pm - 7:14 pm
CLE
-
CLT
22h 49m
1 stop
$134Multiple Airlines
Tue, Apr 14 - Tue, Apr 21
Breeze Airways Logo
10:35 am - 12:03 pm
GSP
-
PIT
1h 28mnonstop
Breeze Airways Logo
5:44 pm - 7:11 pm
PIT
-
GSP
1h 27mnonstop
$208Breeze Airways
Thu, Jun 4 - Sun, Jun 7
Delta Logo
5:38 am - 11:37 am
CAE
-
CLE
5h 59m
1 stop
Delta Logo
6:00 am - 11:11 am
CLE
-
CAE
5h 11m
1 stop
$211Delta
Wed, May 20 - Wed, Jun 3
Delta Logo
7:00 am - 12:10 pm
CAE
-
CLE
5h 10m
1 stop
Delta Logo
6:00 am - 12:28 pm
CLE
-
CAE
6h 28m
1 stop
$240Delta
Wed, Aug 12 - Sun, Aug 16
Breeze Airways Logo
10:35 am - 12:03 pm
GSP
-
PIT
1h 28mnonstop
Breeze Airways Logo
5:44 pm - 7:11 pm
PIT
-
GSP
1h 27mnonstop
$248Breeze Airways
Thu, Jun 4 - Sun, Jun 7
American Airlines Logo
6:00 am - 1:11 pm
GSP
-
PIT
7h 11m
1 stop
American Airlines Logo
7:00 am - 12:14 pm
PIT
-
GSP
5h 14m
1 stop
$255American Airlines
Wed, Apr 22 - Sat, Apr 25
Southwest Logo
5:25 pm - 9:05 pm
GSP
-
PIT
3h 40m
1 stop
Southwest Logo
12:50 pm - 9:40 pm
PIT
-
GSP
8h 50m
2 stops
$260Southwest
Sat, Apr 25 - Wed, Apr 29
Southwest Logo
8:00 am - 11:35 am
GSP
-
PIT
3h 35m
1 stop
Southwest Logo
5:55 pm - 9:50 pm
PIT
-
GSP
3h 55m
1 stop
$262Southwest
Wed, Mar 25 - Mon, Mar 30
American Airlines Logo
6:00 am - 10:16 am
CAE
-
CLE
4h 16m
1 stop
American Airlines Logo
10:56 am - 4:55 pm
CLE
-
CAE
5h 59m
1 stop
$279American Airlines
Fri, Mar 13 - Tue, Mar 17

Spirit Airlines flights from South Carolina to Ohio

Our best Spirit Airlines deals on South Carolina to Ohio flight tickets
Spirit Airlines
Apr 21
MYR10:20 amMyrtle Beach Intl
12h 32m
1 stop
DTW10:52 pmDetroit Metropolitan Wayne County
Apr 25
DTW9:16 amDetroit Metropolitan Wayne County
5h 28m
1 stop
MYR2:44 pmMyrtle Beach Intl
$143
Spirit Airlines
May 13
MYR10:20 amMyrtle Beach Intl
12h 32m
1 stop
DTW10:52 pmDetroit Metropolitan Wayne County
May 19
DTW9:16 amDetroit Metropolitan Wayne County
5h 28m
1 stop
MYR2:44 pmMyrtle Beach Intl
$146
Spirit Airlines
Mar 21
CLT9:00 pmCharlotte Douglas
12h 23m
1 stop
DTW9:23 amDetroit Metropolitan Wayne County
Mar 24
DTW2:06 pmDetroit Metropolitan Wayne County
5h 55m
1 stop
CLT8:01 pmCharlotte Douglas
$148

Delta flights from South Carolina to Ohio

Our best Delta deals on South Carolina to Ohio flight tickets
Delta
Apr 14
CLT5:12 pmCharlotte Douglas
1h 51m
DTW7:03 pmDetroit Metropolitan Wayne County
Apr 18
DTW7:45 pmDetroit Metropolitan Wayne County
1h 43m
CLT9:28 pmCharlotte Douglas
$199
Delta
May 20
CAE5:38 amColumbia Metropolitan
5h 59m
1 stop
CLE11:37 amCleveland Hopkins Intl
Jun 3
CLE6:00 amCleveland Hopkins Intl
5h 11m
1 stop
CAE11:11 amColumbia Metropolitan
$211
Delta
Aug 12
CAE7:00 amColumbia Metropolitan
5h 10m
1 stop
CLE12:10 pmCleveland Hopkins Intl
Aug 16
CLE6:00 amCleveland Hopkins Intl
6h 28m
1 stop
CAE12:28 pmColumbia Metropolitan
$240

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Ohio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 3, 2026.
Use the filters below to find and compare flights from South Carolina to Ohio that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlotteCleveland

CLT - CLE

CLTCLE

Charlotte Douglas

Tue 4/14

10:13 am-12:43 am

1 stop14h 30m

Cleveland Hopkins Intl

Tue 4/21

8:25 pm-7:14 pm

1 stop22h 49m

$130

CharlotteCleveland

CLT - CLE

CLTCLE

Charlotte Douglas

Tue 4/14

10:13 am-12:43 am

1 stop14h 30m

Cleveland Hopkins Intl

Tue 4/21

8:25 pm-7:14 pm

1 stop22h 49m

$134

GreenvillePittsburgh

GSP - PIT

GSPPIT

Greenville

Thu 6/4

10:35 am-12:03 pm

Nonstop1h 28m

Pittsburgh

Sun 6/7

5:44 pm-7:11 pm

Nonstop1h 27m

$208

ColumbiaCleveland

CAE - CLE

CAECLE

Columbia Metropolitan

Wed 5/20

5:38 am-11:37 am

1 stop5h 59m

Cleveland Hopkins Intl

Wed 6/3

6:00 am-11:11 am

1 stop5h 11m

$211

ColumbiaCleveland

CAE - CLE

CAECLE

Columbia Metropolitan

Wed 8/12

7:00 am-12:10 pm

1 stop5h 10m

Cleveland Hopkins Intl

Sun 8/16

6:00 am-12:28 pm

1 stop6h 28m

$240

GreenvillePittsburgh

GSP - PIT

GSPPIT

Greenville

Thu 6/4

10:35 am-12:03 pm

Nonstop1h 28m

Pittsburgh

Sun 6/7

5:44 pm-7:11 pm

Nonstop1h 27m

$248

GreenvillePittsburgh

GSP - PIT

GSPPIT

Greenville

Wed 4/22

6:00 am-1:11 pm

1 stop7h 11m

Pittsburgh

Sat 4/25

7:00 am-12:14 pm

1 stop5h 14m

$255

GreenvillePittsburgh

GSP - PIT

GSPPIT

Greenville

Sat 4/25

5:25 pm-9:05 pm

1 stop3h 40m

Pittsburgh

Wed 4/29

12:50 pm-9:40 pm

2 stops8h 50m

$260

GreenvillePittsburgh

GSP - PIT

GSPPIT

Greenville

Wed 3/25

8:00 am-11:35 am

1 stop3h 35m

Pittsburgh

Mon 3/30

5:55 pm-9:50 pm

1 stop3h 55m

$262

ColumbiaCleveland

CAE - CLE

CAECLE

Columbia Metropolitan

Fri 3/13

6:00 am-10:16 am

1 stop4h 16m

Cleveland Hopkins Intl

Tue 3/17

10:56 am-4:55 pm

1 stop5h 59m

$279

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Ohio from

How to get the cheapest flight ticket from South Carolina to Ohio

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Ohio?

In general, October is the cheapest month to fly from South Carolina to Ohio. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $196. If you are unable to visit Ohio during the month of October, then departing from South Carolina during the month September is also very affordable. Most momondo users find prices during this month for around $266.

What is the cheapest South Carolina to Ohio flight route?

Fly from Charleston to Columbus for the best South Carolina - Ohio flight prices

What cabin class options are available on South Carolina to Ohio flights?

There are 2 cabin classes available to choose from on South Carolina to Ohio flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on South Carolina to Ohio flights?

No. A direct flight is the cheapest option for a flight between South Carolina to Ohio.

Cheap South Carolina to Ohio flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Ohio

Best Price Found

$54

Fastest flight time

1h 23m

Direct flights

Every day

Airports in Ohio

108 airports
The best one-way flight to Ohio from South Carolina in the past 72 hours is $54. The best round-trip flight deal from South Carolina to Ohio found on momondo in the last 72 hours is $80.
The fastest flight from South Carolina to Ohio takes 1h 23m
Direct flights go from South Carolina to Ohio every day.
There are 108 airports in Ohio. From South Carolina there are direct flights to Cincinnati Cinci./N. Kentucky (CVG), Detroit Metropolitan Wayne County (DTW), Pittsburgh (PIT), Cleveland Hopkins Intl (CLE) and 1 more.
  • When did momondo last update prices for flights from South Carolina to Ohio?

    Prices for flights from South Carolina to Ohio are updated daily.

  • How many operators does momondo search for flights from South Carolina to Ohio?

  • How old do you have to be to fly from South Carolina to Ohio?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to Ohio.

  • What documentation or ID do you need to fly to Ohio?

    The necessary travel and health documents for your Ohio trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from South Carolina to Ohio?

Best airlines flying from South Carolina to Ohio

Compare and see reviews for airlines that fly from South Carolina to Ohio with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $40Free CancellationRating
7.3
715 reviews
Search Allegiant Air flights
Breeze AirwaysPriceFrom $41Free CancellationRating
8.1
271 reviews
Search Breeze Airways flights
Spirit AirlinesPriceFrom $75Free CancellationRating
6.3
8,489 reviews
Search Spirit Airlines flights
DeltaPriceFrom $100Free CancellationRating
7.9
8,244 reviews
Search Delta flights
SouthwestPriceFrom $156Free CancellationRating
8.0
4,305 reviews
Search Southwest flights
American AirlinesPriceFrom $194Free CancellationRating
7.1
11,376 reviews
Search American Airlines flights
United AirlinesPriceFrom $198Free CancellationRating
7.4
9,381 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Ohio?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from South Carolina to Ohio. momondo saves you time and could save you money on your trip.

Can I find flights from South Carolina to Ohio with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Ohio from South Carolina with this policy.

How can momondo help me find flights from South Carolina to Ohio?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from South Carolina to Ohio.

I’m not ready to book a flight from South Carolina to Ohio right now. Can momondo alert me if prices change?

If you are not ready to book a flight from South Carolina to Ohio now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Ohio and let you know when they change.

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1 adult
Thu 4/2
Thu 4/9

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