Latest deals
Insights
FAQs
Reviews
Price Alerts

Cheap flights from South Carolina to Key West from $89

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Key West departing on 4/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from South Carolina to Key West

Cheap round-trip flights

Enter your travel dates to find the best prices.
Breeze Airways Logo
8:59 pm - 9:09 am
CHS
-
EYW
12h 10m
1 stop
Breeze Airways Logo
11:51 am - 8:38 am
EYW
-
CHS
20h 47m
1 stop
$154Breeze Airways
Sun, Mar 8 - Wed, Mar 11
Breeze Airways Logo
8:59 pm - 9:09 am
CHS
-
EYW
12h 10m
1 stop
Breeze Airways Logo
11:01 am - 9:59 pm
EYW
-
CHS
10h 58m
1 stop
$164Breeze Airways
Sun, Mar 8 - Thu, Mar 12
Multiple Airlines Logo
1:59 pm - 9:06 am
CLT
-
EYW
19h 07m
1 stop
Multiple Airlines Logo
9:46 am - 12:36 am
EYW
-
CLT
14h 50m
1 stop
$171Multiple Airlines
Wed, Mar 18 - Thu, Apr 2
Multiple Airlines Logo
1:59 pm - 9:06 am
CLT
-
EYW
19h 07m
1 stop
Multiple Airlines Logo
11:51 am - 10:55 pm
EYW
-
CLT
11h 04m
1 stop
$172Multiple Airlines
Wed, Mar 25 - Wed, Apr 1
Delta Logo
6:51 am - 10:46 am
GSP
-
EYW
3h 55m
1 stop
Delta Logo
6:23 pm - 11:56 pm
EYW
-
GSP
5h 33m
1 stop
$251Delta
Tue, Apr 28 - Wed, Apr 29
American Airlines Logo
6:45 pm - 10:58 pm
GSP
-
EYW
4h 13m
1 stop
American Airlines Logo
11:24 am - 6:15 pm
EYW
-
GSP
6h 51m
1 stop
$260American Airlines
Thu, May 7 - Tue, May 12
American Airlines Logo
6:54 am - 12:01 pm
MYR
-
EYW
5h 07m
1 stop
American Airlines Logo
6:34 pm - 10:56 pm
EYW
-
MYR
4h 22m
1 stop
$260American Airlines
Tue, Mar 17 - Tue, Mar 24
Delta Logo
10:10 am - 2:24 pm
CAE
-
EYW
4h 14m
1 stop
Delta Logo
7:00 am - 11:17 am
EYW
-
CAE
4h 17m
1 stop
$269Delta
Sat, Aug 15 - Tue, Aug 18
Allegiant Air Logo
8:23 am - 1:24 pm
GSP
-
EYW
5h 01m
1 stop
Allegiant Air Logo
5:12 pm - 2:53 pm
EYW
-
GSP
21h 41m
1 stop
$276Allegiant Air
Thu, May 21 - Wed, May 27
Allegiant Air Logo
8:57 pm - 11:07 am
SAV
-
EYW
14h 10m
1 stop
Allegiant Air Logo
2:32 pm - 10:12 am
EYW
-
SAV
19h 40m
1 stop
$375Allegiant Air
Sun, Aug 2 - Sun, Aug 16

Breeze Airways flights from South Carolina to Key West

Our best Breeze Airways deals on South Carolina to Key West flight tickets
Breeze Airways
Mar 8
CHS8:59 pmCharleston
12h 10m
1 stop
EYW9:09 amKey West
Mar 11
EYW11:51 amKey West
20h 47m
1 stop
CHS8:38 amCharleston
$154
Breeze Airways
Mar 8
CHS8:59 pmCharleston
12h 10m
1 stop
EYW9:09 amKey West
Mar 12
EYW11:01 amKey West
10h 58m
1 stop
CHS9:59 pmCharleston
$164
Breeze Airways
Mar 25
CHS5:16 pmCharleston
17h 05m
1 stop
EYW10:21 amKey West
Apr 1
EYW11:51 amKey West
20h 47m
1 stop
CHS8:38 amCharleston
$168

Spirit Airlines flights from South Carolina to Key West

Our best Spirit Airlines deals on South Carolina to Key West flight tickets
Spirit Airlines
May 7
CLT6:00 amCharlotte Douglas
5h 11m
1 stop
EYW11:11 amKey West
May 10
EYW12:06 pmKey West
10h 27m
1 stop
CLT10:33 pmCharlotte Douglas
$219
Spirit Airlines
Mar 16
CLT6:00 amCharlotte Douglas
7h 37m
1 stop
EYW1:37 pmKey West
Mar 19
EYW12:25 pmKey West
7h 52m
1 stop
CLT8:17 pmCharlotte Douglas
$223
Spirit Airlines
Mar 30
CLT6:00 amCharlotte Douglas
7h 37m
1 stop
EYW1:37 pmKey West
Apr 3
EYW2:35 pmKey West
5h 42m
1 stop
CLT8:17 pmCharlotte Douglas
$251

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 25, 2026.
Use the filters below to find and compare flights from South Carolina to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlestonKey West

CHS - EYW

CHSEYW

Charleston

Sun 3/8

8:59 pm-9:09 am

1 stop12h 10m

Key West

Wed 3/11

11:51 am-8:38 am

1 stop20h 47m

$154

CharlestonKey West

CHS - EYW

CHSEYW

Charleston

Sun 3/8

8:59 pm-9:09 am

1 stop12h 10m

Key West

Thu 3/12

11:01 am-9:59 pm

1 stop10h 58m

$164

CharlotteKey West

CLT - EYW

CLTEYW

Charlotte Douglas

Wed 3/18

1:59 pm-9:06 am

1 stop19h 07m

Key West

Thu 4/2

9:46 am-12:36 am

1 stop14h 50m

$171

CharlotteKey West

CLT - EYW

CLTEYW

Charlotte Douglas

Wed 3/25

1:59 pm-9:06 am

1 stop19h 07m

Key West

Wed 4/1

11:51 am-10:55 pm

1 stop11h 04m

$172

GreenvilleKey West

GSP - EYW

GSPEYW

Greenville

Tue 4/28

6:51 am-10:46 am

1 stop3h 55m

Key West

Wed 4/29

6:23 pm-11:56 pm

1 stop5h 33m

$251

GreenvilleKey West

GSP - EYW

GSPEYW

Greenville

Thu 5/7

6:45 pm-10:58 pm

1 stop4h 13m

Key West

Tue 5/12

11:24 am-6:15 pm

1 stop6h 51m

$260

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Tue 3/17

6:54 am-12:01 pm

1 stop5h 07m

Key West

Tue 3/24

6:34 pm-10:56 pm

1 stop4h 22m

$260

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

Sat 8/15

10:10 am-2:24 pm

1 stop4h 14m

Key West

Tue 8/18

7:00 am-11:17 am

1 stop4h 17m

$269

GreenvilleKey West

GSP - EYW

GSPEYW

Greenville

Thu 5/21

8:23 am-1:24 pm

1 stop5h 01m

Key West

Wed 5/27

5:12 pm-2:53 pm

1 stop21h 41m

$276

SavannahKey West

SAV - EYW

SAVEYW

Savannah/Hilton Head

Sun 8/2

8:57 pm-11:07 am

1 stop14h 10m

Key West

Sun 8/16

2:32 pm-10:12 am

1 stop19h 40m

$375

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Key West from

How to get the cheapest flight ticket from South Carolina to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Key West?

In general, September is the cheapest month to fly from South Carolina to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $352. If you are unable to visit Key West during the month of September, then departing from South Carolina during the month August is also very affordable. Most momondo users find prices during this month for around $356.

How far in advance should I book a flight to Key West?

You are more likely to see cheaper flights to Key West from South Carolina when booking weeks ahead of your departure date. In general, you can expect to find flights to Key West for around $455 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Key West from South Carolina for as low as $338 on momondo.

Can stopping save me money on South Carolina to Key West flights?

You could potentially save up to 75% on your flight if you consider stops on a South Carolina to Key West flight.

Cheap South Carolina to Key West flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Key West

Fastest flight time

2h 14m

Direct flights

Every day

Airports in Key West

1 airport
The fastest flight from South Carolina to Key West takes 2h 14m
Direct flights go from South Carolina to Key West every day.
There is 1 airport in Key West. From South Carolina there are direct flights to Key West (EYW).
Search flight deals

  • When did momondo last update prices for flights from South Carolina to Key West Airport?

    Prices for flights from South Carolina to Key West Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from South Carolina to Key West Airport?

  • How old do you have to be to fly from South Carolina to Key West Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The required travel and health documents for your Key West Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Key West Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from South Carolina to Key West

Compare and see reviews for airlines that fly from South Carolina to Key West with momondo
Airline
Rating
Free Cancellation
Price
Breeze AirwaysPriceFrom $95Free CancellationRating
8.1
271 reviews
Search Breeze Airways flights
DeltaPriceFrom $125Free CancellationRating
7.9
8,237 reviews
Search Delta flights
American AirlinesPriceFrom $253Free CancellationRating
7.2
11,352 reviews
Search American Airlines flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Key West?

It is quick and easy to find South Carolina to Key West flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Key West that suits you.

Can I find flights from South Carolina to Key West with flexible booking policies on momondo?

Yes. All flights to Key West from South Carolina on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from South Carolina to Key West?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Key West from South Carolina.

I’m not ready to book a flight from South Carolina to Key West right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Key West, momondo offers a useful price alert feature which will track prices for flights to Key West from South Carolina and alert you when they change.

An easier way to manage your Key West trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Fri 3/27
Fri 4/3
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States