Latest deals
Insights
FAQs
Reviews
Price Alerts

Cheap flights from South Carolina to Key West from $94

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Key West departing on 4/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from South Carolina to Key West

Cheap round-trip flights

Enter your travel dates to find the best prices.
Breeze Airways Logo
10:17 am - 11:06 am
CHS
-
EYW
24h 49m
1 stop
Breeze Airways Logo
1:14 pm - 12:50 pm
EYW
-
CHS
23h 36m
1 stop
$146Breeze Airways
Tue, May 12 - Tue, May 19
Breeze Airways Logo
3:40 pm - 12:31 pm
GSP
-
EYW
20h 51m
1 stop
Breeze Airways Logo
11:04 am - 9:46 am
EYW
-
GSP
22h 42m
1 stop
$176Breeze Airways
Sun, Jun 14 - Thu, Jun 18
Multiple Airlines Logo
9:32 pm - 12:26 pm
CLT
-
EYW
14h 54m
1 stop
Multiple Airlines Logo
11:51 am - 1:44 pm
EYW
-
CLT
25h 53m
1 stop
$181Multiple Airlines
Sun, Apr 26 - Wed, Apr 29
Multiple Airlines Logo
3:22 pm - 1:58 pm
GSP
-
EYW
22h 36m
1 stop
Multiple Airlines Logo
11:04 am - 7:39 pm
EYW
-
GSP
8h 35m
1 stop
$198Multiple Airlines
Fri, May 22 - Thu, May 28
Delta Logo
5:35 am - 11:00 am
CAE
-
EYW
5h 25m
1 stop
Delta Logo
7:00 am - 11:17 am
EYW
-
CAE
4h 17m
1 stop
$323Delta
Wed, Aug 5 - Wed, Aug 12
Allegiant Air Logo
4:00 pm - 11:07 am
SAV
-
EYW
19h 07m
1 stop
Allegiant Air Logo
11:57 am - 11:24 pm
EYW
-
SAV
11h 27m
1 stop
$351Allegiant Air
Thu, Aug 6 - Mon, Aug 10
Allegiant Air Logo
1:36 pm - 11:11 am
SAV
-
EYW
21h 35m
1 stop
Allegiant Air Logo
12:34 pm - 12:55 pm
EYW
-
SAV
24h 21m
1 stop
$362Allegiant Air
Sun, May 10 - Sun, May 17
Delta Logo
1:47 pm - 7:51 pm
CAE
-
EYW
6h 04m
1 stop
Delta Logo
6:18 pm - 11:49 pm
EYW
-
CAE
5h 31m
1 stop
$374Delta
Sun, Jul 12 - Sat, Jul 18
American Airlines Logo
12:01 pm - 4:35 pm
CAE
-
EYW
4h 34m
1 stop
American Airlines Logo
11:35 am - 7:47 pm
EYW
-
CAE
8h 12m
2 stops
$389American Airlines
Tue, Apr 28 - Sat, May 2
American Airlines Logo
1:48 pm - 10:58 pm
CAE
-
EYW
9h 10m
2 stops
American Airlines Logo
11:35 am - 7:47 pm
EYW
-
CAE
8h 12m
2 stops
$394American Airlines
Tue, Apr 28 - Sat, May 2

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Breeze Airways flights from South Carolina to Key West

Our best Breeze Airways deals on South Carolina to Key West flight tickets
Breeze Airways
Apr 20
GSP4:07 pmGreenville
20h 14m
1 stop
EYW12:21 pmKey West
Apr 24
EYW1:06 pmKey West
6h 32m
1 stop
GSP7:38 pmGreenville
$141
Breeze Airways
May 12
CHS10:17 amCharleston
24h 49m
1 stop
EYW11:06 amKey West
May 19
EYW1:14 pmKey West
23h 36m
1 stop
CHS12:50 pmCharleston
$146
Breeze Airways
Jun 14
GSP3:40 pmGreenville
20h 51m
1 stop
EYW12:31 pmKey West
Jun 18
EYW11:04 amKey West
22h 42m
1 stop
GSP9:46 amGreenville
$176

American Airlines flights from South Carolina to Key West

Our best American Airlines deals on South Carolina to Key West flight tickets
American Airlines
May 7
GSP6:45 pmGreenville
4h 13m
1 stop
EYW10:58 pmKey West
May 12
EYW5:25 pmKey West
5h 37m
1 stop
GSP11:02 pmGreenville
$310
American Airlines
May 7
GSP6:45 pmGreenville
4h 13m
1 stop
EYW10:58 pmKey West
May 12
EYW3:58 pmKey West
7h 04m
2 stops
GSP11:02 pmGreenville
$315
American Airlines
May 4
MYR5:00 amMyrtle Beach Intl
6h 16m
1 stop
EYW11:16 amKey West
May 11
EYW4:20 pmKey West
6h 04m
1 stop
MYR10:24 pmMyrtle Beach Intl
$329

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 15, 2026.
Use the filters below to find and compare flights from South Carolina to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlestonKey West

CHS - EYW

CHSEYW

Charleston

Tue 5/12

10:17 am-11:06 am

1 stop24h 49m

Key West

Tue 5/19

1:14 pm-12:50 pm

1 stop23h 36m

$146

GreenvilleKey West

GSP - EYW

GSPEYW

Greenville

Sun 6/14

3:40 pm-12:31 pm

1 stop20h 51m

Key West

Thu 6/18

11:04 am-9:46 am

1 stop22h 42m

$176

CharlotteKey West

CLT - EYW

CLTEYW

Charlotte Douglas

Sun 4/26

9:32 pm-12:26 pm

1 stop14h 54m

Key West

Wed 4/29

11:51 am-1:44 pm

1 stop25h 53m

$181

GreenvilleKey West

GSP - EYW

GSPEYW

Greenville

Fri 5/22

3:22 pm-1:58 pm

1 stop22h 36m

Key West

Thu 5/28

11:04 am-7:39 pm

1 stop8h 35m

$198
Quickest round-trip

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

Wed 8/5

5:35 am-11:00 am

1 stop5h 25m

Key West

Wed 8/12

7:00 am-11:17 am

1 stop4h 17m

$323

SavannahKey West

SAV - EYW

SAVEYW

Savannah/Hilton Head

Thu 8/6

4:00 pm-11:07 am

1 stop19h 07m

Key West

Mon 8/10

11:57 am-11:24 pm

1 stop11h 27m

$351

SavannahKey West

SAV - EYW

SAVEYW

Savannah/Hilton Head

Sun 5/10

1:36 pm-11:11 am

1 stop21h 35m

Key West

Sun 5/17

12:34 pm-12:55 pm

1 stop24h 21m

$362

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

Sun 7/12

1:47 pm-7:51 pm

1 stop6h 04m

Key West

Sat 7/18

6:18 pm-11:49 pm

1 stop5h 31m

$374

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

Tue 4/28

12:01 pm-4:35 pm

1 stop4h 34m

Key West

Sat 5/2

11:35 am-7:47 pm

2 stops8h 12m

$389

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

Tue 4/28

1:48 pm-10:58 pm

2 stops9h 10m

Key West

Sat 5/2

11:35 am-7:47 pm

2 stops8h 12m

$394

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Key West from

How to get the cheapest flight ticket from South Carolina to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Key West?

In general, August is the cheapest month to fly from South Carolina to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $251. If you are unable to visit Key West during the month of August, then departing from South Carolina during the month September is also very affordable. Most momondo users find prices during this month for around $336.

How far in advance should I book a flight to Key West?

You are more likely to see cheaper flights to Key West from South Carolina when booking weeks ahead of your departure date. In general, you can expect to find flights to Key West for around $435 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Key West from South Carolina for as low as $329 on momondo.

Can stopping save me money on South Carolina to Key West flights?

You could potentially save up to 69% on your flight if you consider stops on a South Carolina to Key West flight.

Cheap South Carolina to Key West flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Key West

Fastest flight time

2h 15m

Direct flights

Every day

Airports in Key West

1 airport
The fastest flight from South Carolina to Key West takes 2h 15m
Direct flights go from South Carolina to Key West every day.
There is 1 airport in Key West. From South Carolina there are direct flights to Key West (EYW).
Search flight deals

Frequently asked questions about flying from South Carolina to Key West

  • When did momondo last update prices for flights from South Carolina to Key West Airport?

    Prices for flights from South Carolina to Key West Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from South Carolina to Key West Airport?

  • How old do you have to be to fly from South Carolina to Key West Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The required travel and health documents for your Key West Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Key West Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from South Carolina to Key West

Compare and see reviews for airlines that fly from South Carolina to Key West with momondo
Airline
Rating
Free Cancellation
Price
Breeze AirwaysPriceFrom $106Free CancellationRating
8.1
279 reviews
Search Breeze Airways flights
DeltaPriceFrom $125Free CancellationRating
7.9
8,407 reviews
Search Delta flights
American AirlinesPriceFrom $248Free CancellationRating
7.1
11,582 reviews
Search American Airlines flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Key West?

It is quick and easy to find South Carolina to Key West flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Key West that suits you.

Can I find flights from South Carolina to Key West with flexible booking policies on momondo?

Yes. All flights to Key West from South Carolina on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from South Carolina to Key West?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Key West from South Carolina.

I’m not ready to book a flight from South Carolina to Key West right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Key West, momondo offers a useful price alert feature which will track prices for flights to Key West from South Carolina and alert you when they change.

An easier way to manage your Key West trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Fri 5/15
Fri 5/22
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States