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Cheap flights from South Carolina to Key West from $55

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from South Carolina to Key West

Cheap round-trip flights

Enter your travel dates to find the best prices.
Breeze Airways Logo
6:00 am - 9:24 amCHS  Charleston-EYW Key West
3h 24m1 stop Tampa
Breeze Airways Logo
10:04 am - 1:24 pmEYW  Key West-CHS Charleston
3h 20m1 stop Tampa
$104Breeze Airways
Sat, Nov 14 - Wed, Nov 18
Breeze Airways Logo
6:00 am - 9:24 amCHS  Charleston-EYW Key West
3h 24m1 stop Tampa
Breeze Airways Logo
10:04 am - 1:24 pmEYW  Key West-CHS Charleston
3h 20m1 stop Tampa
$105Breeze Airways
Sat, Nov 14 - Wed, Nov 18
Breeze Airways Logo
6:00 am - 9:24 amCHS  Charleston-EYW Key West
3h 24m1 stop Tampa
Breeze Airways Logo
10:04 am - 1:24 pmEYW  Key West-CHS Charleston
3h 20m1 stop Tampa
$110Breeze Airways
Sat, Nov 14 - Wed, Nov 18
Multiple Airlines Logo
7:30 am - 3:17 pmCHS  Charleston-EYW Key West
7h 47m1 stop Tampa
Multiple Airlines Logo
10:59 am - 8:38 amEYW  Key West-CHS Charleston
21h 39m1 stop Orlando
$217Multiple Airlines
Sat, Jan 23 - Tue, Jan 26
Multiple Airlines Logo
10:15 pm - 1:12 pmCHS  Charleston-EYW Key West
14h 57m2 stops Fort Lauderdale Knoxville McGhee Tyson
Multiple Airlines Logo
10:45 am - 2:05 pmEYW  Key West-CHS Charleston
3h 20m1 stop Tampa
$219Multiple Airlines
Sun, Dec 6 - Wed, Dec 9
Allegiant Air Logo
5:44 pm - 2:08 pmGSP  Greenville-EYW Key West
20h 24m1 stop Tampa St. Petersburg
Allegiant Air Logo
7:23 pm - 5:48 pmEYW  Key West-GSP Greenville
22h 25m1 stop Orlando Sanford Intl
$270Allegiant Air
Sun, Mar 7 - Thu, Mar 11
American Airlines Logo
5:30 am - 9:28 amGSP  Greenville-EYW Key West
3h 58m1 stop Miami
American Airlines Logo
11:32 am - 6:29 pmEYW  Key West-GSP Greenville
6h 57m1 stop Miami
$323American Airlines
Sat, Feb 6 - Tue, Feb 9
Delta Logo
5:38 am - 10:53 amGSP  Greenville-EYW Key West
5h 15m1 stop Atlanta Hartsfield-Jackson
Delta Logo
2:50 pm - 6:47 pmEYW  Key West-GSP Greenville
3h 57m1 stop Atlanta Hartsfield-Jackson
$331Delta
Fri, Jan 8 - Tue, Jan 12
Delta Logo
2:15 pm - 7:43 pmMYR  Myrtle Beach Intl-EYW Key West
5h 28m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:00 pm - 11:35 pmEYW  Key West-MYR Myrtle Beach Intl
5h 35m1 stop Atlanta Hartsfield-Jackson
$339Delta
Tue, Mar 9 - Tue, Mar 16
American Airlines Logo
9:35 am - 6:53 pmGSP  Greenville-EYW Key West
9h 18m2 stops Charlotte Douglas Miami
American Airlines Logo
1:52 pm - 7:00 pmEYW  Key West-GSP Greenville
5h 08m1 stop Charlotte Douglas
$397American Airlines
Wed, Nov 25 - Wed, Dec 2

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Delta flights from South Carolina to Key West

Our best Delta deals on South Carolina to Key West flight tickets
Delta
Jan 8
GSP5:38 amGreenville
5h 15m
1 stop
EYW10:53 amKey West
Jan 12
EYW2:50 pmKey West
3h 57m
1 stop
GSP6:47 pmGreenville
$331
Delta
Mar 9
MYR2:15 pmMyrtle Beach Intl
5h 28m
1 stop
EYW7:43 pmKey West
Mar 16
EYW6:00 pmKey West
5h 35m
1 stop
MYR11:35 pmMyrtle Beach Intl
$339
Delta
Feb 5
CAE10:49 amColumbia Metropolitan
5h 15m
1 stop
EYW4:04 pmKey West
Feb 8
EYW7:30 amKey West
6h 19m
1 stop
CAE1:49 pmColumbia Metropolitan
$353

American Airlines flights from South Carolina to Key West

Our best American Airlines deals on South Carolina to Key West flight tickets
American Airlines
Feb 6
GSP5:30 amGreenville
3h 58m
1 stop
EYW9:28 amKey West
Feb 9
EYW11:32 amKey West
6h 57m
1 stop
GSP6:29 pmGreenville
$323
American Airlines
Nov 25
GSP9:35 amGreenville
9h 18m
2 stops
EYW6:53 pmKey West
Dec 2
EYW1:52 pmKey West
5h 08m
1 stop
GSP7:00 pmGreenville
$397
American Airlines
Jan 8
GSP5:30 amGreenville
3h 58m
1 stop
EYW9:28 amKey West
Jan 12
EYW9:58 amKey West
6h 53m
2 stops
GSP4:51 pmGreenville
$405

momondo Fare Finder

 
Use the filters below to find and compare flights from South Carolina to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

CharlestonKey West

CHS Charleston - EYW Key West

CHSEYW

Charleston

Sat 11/14

6:00 am-9:24 am

1 stop3h 24m

Key West

Wed 11/18

10:04 am-1:24 pm

1 stop3h 20m

$104

CharlestonKey West

CHS Charleston - EYW Key West

CHSEYW

Charleston

Sat 11/14

6:00 am-9:24 am

1 stop3h 24m

Key West

Wed 11/18

10:04 am-1:24 pm

1 stop3h 20m

$105

CharlestonKey West

CHS Charleston - EYW Key West

CHSEYW

Charleston

Sat 11/14

6:00 am-9:24 am

1 stop3h 24m

Key West

Wed 11/18

10:04 am-1:24 pm

1 stop3h 20m

$110

CharlestonKey West

CHS Charleston - EYW Key West

CHSEYW

Charleston

Sat 1/23

7:30 am-3:17 pm

1 stop7h 47m

Key West

Tue 1/26

10:59 am-8:38 am

1 stop21h 39m

$217

CharlestonKey West

CHS Charleston - EYW Key West

CHSEYW

Charleston

Sun 12/6

10:15 pm-1:12 pm

2 stops14h 57m

Key West

Wed 12/9

10:45 am-2:05 pm

1 stop3h 20m

$219

GreenvilleKey West

GSP Greenville - EYW Key West

GSPEYW

Greenville

Sun 3/7

5:44 pm-2:08 pm

1 stop20h 24m

Key West

Thu 3/11

7:23 pm-5:48 pm

1 stop22h 25m

$270

GreenvilleKey West

GSP Greenville - EYW Key West

GSPEYW

Greenville

Sat 2/6

5:30 am-9:28 am

1 stop3h 58m

Key West

Tue 2/9

11:32 am-6:29 pm

1 stop6h 57m

$323

GreenvilleKey West

GSP Greenville - EYW Key West

GSPEYW

Greenville

Fri 1/8

5:38 am-10:53 am

1 stop5h 15m

Key West

Tue 1/12

2:50 pm-6:47 pm

1 stop3h 57m

$331

Myrtle BeachKey West

MYR Myrtle Beach Intl - EYW Key West

MYREYW

Myrtle Beach Intl

Tue 3/9

2:15 pm-7:43 pm

1 stop5h 28m

Key West

Tue 3/16

6:00 pm-11:35 pm

1 stop5h 35m

$339

GreenvilleKey West

GSP Greenville - EYW Key West

GSPEYW

Greenville

Wed 11/25

9:35 am-6:53 pm

2 stops9h 18m

Key West

Wed 12/2

1:52 pm-7:00 pm

1 stop5h 08m

$397

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
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See travel insights to Key West from

How to get the cheapest flight ticket from South Carolina to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Key West?

In general, August is the cheapest month to fly from South Carolina to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $366. If you are unable to visit Key West during the month of August, then departing from South Carolina during the month September is also very affordable. Most momondo users find prices during this month for around $377.

Cheap South Carolina to Key West flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Key West

Best Price Found

$55

Fastest flight time

2h 17m

Direct flights

None
The best one-way flight to Key West from South Carolina in the past 72 hours is $55. The best round-trip flight deal from South Carolina to Key West found on momondo in the last 72 hours is $104.
The fastest flight from South Carolina to Key West takes 2h 17m
There are no direct flights from South Carolina to Key West. There are no popular flight routes from South Carolina to Key West.
Search flight deals

Frequently asked questions about flying from South Carolina to Key West

  • When did momondo last update prices for flights from South Carolina to Key West Airport?

    Prices for flights from South Carolina to Key West Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from South Carolina to Key West Airport?

  • How old do you have to be to fly from South Carolina to Key West Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The required travel and health documents for your Key West Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Key West Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from South Carolina to Key West

Compare and see reviews for airlines that fly from South Carolina to Key West with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $76Free CancellationRating
7.3
680 reviews
Search Allegiant Air flights
Breeze AirwaysPriceFrom $101Free CancellationRating
8.2
324 reviews
Search Breeze Airways flights
DeltaPriceFrom $125Free CancellationRating
7.8
8,698 reviews
Search Delta flights
American AirlinesPriceFrom $268Free CancellationRating
7.0
12,223 reviews
Search American Airlines flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Key West?

It is quick and easy to find South Carolina to Key West flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Key West that suits you.

Can I find flights from South Carolina to Key West with flexible booking policies on momondo?

Yes. All flights to Key West from South Carolina on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from South Carolina to Key West?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Key West from South Carolina.

I’m not ready to book a flight from South Carolina to Key West right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Key West, momondo offers a useful price alert feature which will track prices for flights to Key West from South Carolina and alert you when they change.

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