How many flights depart from South Carolina to Key West on average per week?

As of September 2026, 12 flights take off from South Carolina and land in Key West each week. The most common flight departure day for this route is Mon, with 17% of weekly flights taking off on this day.

What is the cheapest airline that flies from South Carolina to Key West?

Breeze Airways, Allegiant Air, and Delta are the most popular carriers operating from South Carolina to Key West

How long does it take to fly to Key West?

If you’re flying from a popular airport in South Carolina, such as Charleston or Greenville, and flying into Key West, then you can expect flight times to average 3h 24m and 4h 13m, respectively.

What airlines fly to Key West?

American Airlines, Delta and Breeze Airways are the top three most popular airlines that fly to Key West from South Carolina according to our data. American Airlines is the first choice among our users, with 55% of people opting to fly with this airline when traveling to Key West. Keep in mind that there are 4 different airlines that fly to Key West on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from South Carolina to Key West Airport?

Prices for flights from South Carolina to Key West Airport are refreshed on a daily basis.

How many operators does momondo search for flights from South Carolina to Key West Airport?

There are 4 operators available for flights from South Carolina to Key West Airport as of September 2026.

How old do you have to be to fly from South Carolina to Key West Airport?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to Key West Airport.

What documentation or ID do you need to fly to Key West Airport?

The required travel and health documents for your Key West Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Key West Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$60 Cheap Flights from South Carolina to Key West in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from South Carolina to Key West

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:00 am - 9:24 amCHS Charleston-EYW Key West

3h 24m1 stop Tampa

10:04 am - 1:24 pmEYW Key West-CHS Charleston

3h 20m1 stop Tampa

$105Breeze Airways

Sat, Sep 19 - Wed, Sep 23

6:00 am - 9:24 amCHS Charleston-EYW Key West

3h 24m1 stop Tampa

10:04 am - 1:24 pmEYW Key West-CHS Charleston

3h 20m1 stop Tampa

$144Breeze Airways

Sat, Sep 19 - Wed, Sep 23

6:05 am - 10:19 amCLT Charlotte Douglas-EYW Key West

28h 14m1 stop Orlando

10:59 am - 7:55 amEYW Key West-CLT Charlotte Douglas

20h 56m1 stop Orlando

$206Multiple Airlines

Wed, Nov 18 - Tue, Dec 15

6:05 am - 8:30 amCLT Charlotte Douglas-EYW Key West

26h 25m1 stop Orlando

8:25 am - 8:37 amEYW Key West-CLT Charlotte Douglas

24h 12m1 stop Orlando Sanford Intl

$226Multiple Airlines

Sun, Nov 8 - Fri, Nov 13

6:45 am - 10:58 amGSP Greenville-EYW Key West

4h 13m1 stop Atlanta Hartsfield-Jackson

6:00 pm - 11:37 pmEYW Key West-GSP Greenville

5h 37m1 stop Atlanta Hartsfield-Jackson

$323Delta

Wed, Jan 20 - Sat, Jan 23

3:42 pm - 7:43 pmGSP Greenville-EYW Key West

4h 01m1 stop Atlanta Hartsfield-Jackson

7:00 am - 10:58 amEYW Key West-GSP Greenville

3h 58m1 stop Atlanta Hartsfield-Jackson

$323Delta

Tue, Jan 19 - Wed, Jan 27

5:30 am - 9:22 amGSP Greenville-EYW Key West

3h 52m1 stop Miami

7:33 pm - 11:59 pmEYW Key West-GSP Greenville

4h 26m1 stop Miami

$326American Airlines

Wed, Jan 20 - Sat, Jan 23

10:50 am - 7:03 pmGSP Greenville-EYW Key West

8h 13m2 stops Charlotte Douglas Miami

7:33 pm - 11:59 pmEYW Key West-GSP Greenville

4h 26m1 stop Miami

$367American Airlines

Wed, Jan 20 - Sat, Jan 23

11:56 am - 5:47 pmSAV Savannah/Hilton Head-EYW Key West

5h 51m1 stop Pittsburgh

11:20 am - 4:02 pmEYW Key West-SAV Savannah/Hilton Head

28h 42m1 stop Cincinnati Cinci./N. Kentucky

$487Allegiant Air

Fri, Oct 16 - Fri, Oct 23

3:12 pm - 12:43 pmSAV Savannah/Hilton Head-EYW Key West

45h 31m2 stops Cincinnati Cinci./N. Kentucky Orlando Sanford Intl

11:20 am - 4:02 pmEYW Key West-SAV Savannah/Hilton Head

28h 42m1 stop Cincinnati Cinci./N. Kentucky

$518Allegiant Air

Fri, Oct 16 - Fri, Oct 23

Cheap last minute flights

Enter your travel dates to find the best prices.

3:42 pm - 10:19 amCHS Charleston-EYW Key West

18h 37m1 stop Orlando

10:59 am - 8:38 amEYW Key West-CHS Charleston

21h 39m1 stop Orlando

$165Breeze Airways

Wed, Sep 9 - Mon, Sep 14

8:24 pm - 11:21 amGSP Greenville-EYW Key West

14h 57m1 stop Tampa

12:59 pm - 5:23 pmEYW Key West-GSP Greenville

4h 24m1 stop Tampa

$239Breeze Airways

Wed, Sep 9 - Fri, Sep 11

3:42 pm - 10:19 amCHS Charleston-EYW Key West

18h 37m1 stop Orlando

12:59 pm - 12:41 pmEYW Key West-CHS Charleston

23h 42m2 stops Tampa Columbus

$283Breeze Airways

Wed, Sep 9 - Mon, Sep 14

9:40 pm - 10:19 amCLT Charlotte Douglas-EYW Key West

12h 39m1 stop Orlando

10:59 am - 8:35 amEYW Key West-CLT Charlotte Douglas

21h 36m1 stop Orlando

$372Multiple Airlines

Wed, Sep 9 - Fri, Sep 11

8:50 pm - 9:24 amCLT Charlotte Douglas-EYW Key West

36h 34m2 stops Philadelphia Tampa

10:59 am - 8:35 amEYW Key West-CLT Charlotte Douglas

21h 36m1 stop Orlando

$380Multiple Airlines

Thu, Sep 10 - Thu, Sep 17

3:15 pm - 9:24 amCLT Charlotte Douglas-EYW Key West

18h 09m2 stops Philadelphia Tampa

10:59 am - 8:35 amEYW Key West-CLT Charlotte Douglas

21h 36m1 stop Orlando

$380Multiple Airlines

Tue, Sep 8 - Thu, Sep 10

2:32 pm - 8:00 pmCHS Charleston-EYW Key West

5h 28m1 stop Atlanta Hartsfield-Jackson

7:40 am - 11:38 amEYW Key West-CHS Charleston

3h 58m1 stop Atlanta Hartsfield-Jackson

$393Delta

Fri, Sep 11 - Tue, Sep 15

6:00 am - 10:57 amCHS Charleston-EYW Key West

4h 57m1 stop Miami

1:47 pm - 9:06 pmEYW Key West-CHS Charleston

7h 19m2 stops Miami Charlotte Douglas

$422American Airlines

Fri, Sep 11 - Tue, Sep 15

6:00 am - 10:56 amSAV Savannah/Hilton Head-EYW Key West

4h 56m1 stop Miami

7:47 pm - 11:59 pmEYW Key West-SAV Savannah/Hilton Head

4h 12m1 stop Miami

$505American Airlines

Tue, Sep 8 - Sat, Sep 12

2:32 pm - 8:00 pmCHS Charleston-EYW Key West

5h 28m1 stop Atlanta Hartsfield-Jackson

7:40 am - 11:38 amEYW Key West-CHS Charleston

3h 58m1 stop Atlanta Hartsfield-Jackson

$544Delta

Fri, Sep 11 - Tue, Sep 15

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

Breeze Airways flights from South Carolina to Key West

Our best Breeze Airways deals on South Carolina to Key West flight tickets

Breeze Airways

Sep 19

CHS6:00 amCharleston

3h 24m

1 stop

EYW9:24 amKey West

Sep 23

EYW10:04 amKey West

3h 20m

1 stop

CHS1:24 pmCharleston

$105

Breeze Airways

Sep 19

CHS6:00 amCharleston

3h 24m

1 stop

EYW9:24 amKey West

Sep 23

EYW10:04 amKey West

3h 20m

1 stop

CHS1:24 pmCharleston

$144

Breeze Airways

Sep 26

CHS6:00 amCharleston

3h 24m

1 stop

EYW9:24 amKey West

Oct 1

EYW10:59 amKey West

21h 49m

1 stop

CHS8:48 amCharleston

$154

Delta flights from South Carolina to Key West

Our best Delta deals on South Carolina to Key West flight tickets

Delta

Jan 20

GSP6:45 amGreenville

4h 13m

1 stop

EYW10:58 amKey West

Jan 23

EYW6:00 pmKey West

5h 37m

1 stop

GSP11:37 pmGreenville

$323

Delta

Jan 18

GSP6:45 amGreenville

6h 23m

1 stop

EYW1:08 pmKey West

Jan 23

EYW6:00 pmKey West

5h 37m

1 stop

GSP11:37 pmGreenville

$331

Delta

Oct 24

CAE6:00 amColumbia Metropolitan

4h 47m

1 stop

EYW10:47 amKey West

Oct 28

EYW7:40 amKey West

5h 34m

1 stop

CAE1:14 pmColumbia Metropolitan

$333

momondo Fare Finder

Use the filters below to find and compare flights from South Carolina to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Quickest round-trip

CharlestonKey West

CHS Charleston - EYW Key West

CHSEYW

Charleston

Sat 9/19

6:00 am-9:24 am

1 stop3h 24m

Key West

Wed 9/23

10:04 am-1:24 pm

1 stop3h 20m

$105

CharlestonKey West

CHS Charleston - EYW Key West

CHSEYW

Charleston

Sat 9/19

6:00 am-9:24 am

1 stop3h 24m

Key West

Wed 9/23

10:04 am-1:24 pm

1 stop3h 20m

$144

CharlotteKey West

CLT Charlotte Douglas - EYW Key West

CLTEYW

Charlotte Douglas

Wed 11/18

6:05 am-10:19 am

1 stop28h 14m

Key West

Tue 12/15

10:59 am-7:55 am

1 stop20h 56m

$206

CharlotteKey West

CLT Charlotte Douglas - EYW Key West

CLTEYW

Charlotte Douglas

Sun 11/8

6:05 am-8:30 am

1 stop26h 25m

Key West

Fri 11/13

8:25 am-8:37 am

1 stop24h 12m

$226

GreenvilleKey West

GSP Greenville - EYW Key West

GSPEYW

Greenville

Wed 1/20

6:45 am-10:58 am

1 stop4h 13m

Key West

Sat 1/23

6:00 pm-11:37 pm

1 stop5h 37m

$323

GreenvilleKey West

GSP Greenville - EYW Key West

GSPEYW

Greenville

Tue 1/19

3:42 pm-7:43 pm

1 stop4h 01m

Key West

Wed 1/27

7:00 am-10:58 am

1 stop3h 58m

$323

GreenvilleKey West

GSP Greenville - EYW Key West

GSPEYW

Greenville

Wed 1/20

5:30 am-9:22 am

1 stop3h 52m

Key West

Sat 1/23

7:33 pm-11:59 pm

1 stop4h 26m

$326

GreenvilleKey West

GSP Greenville - EYW Key West

GSPEYW

Greenville

Wed 1/20

10:50 am-7:03 pm

2 stops8h 13m

Key West

Sat 1/23

7:33 pm-11:59 pm

1 stop4h 26m

$367

SavannahKey West

SAV Savannah/Hilton Head - EYW Key West

SAVEYW

Savannah/Hilton Head

Fri 10/16

11:56 am-5:47 pm

1 stop5h 51m

Key West

Fri 10/23

11:20 am-4:02 pm

1 stop28h 42m

$487

SavannahKey West

SAV Savannah/Hilton Head - EYW Key West

SAVEYW

Savannah/Hilton Head

Fri 10/16

3:12 pm-12:43 pm

2 stops45h 31m

Key West

Fri 10/23

11:20 am-4:02 pm

1 stop28h 42m

$518

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from South Carolina to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Key West?

In general, August is the cheapest month to fly from South Carolina to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $366. If you are unable to visit Key West during the month of August, then departing from South Carolina during the month September is also very affordable. Most momondo users find prices during this month for around $377.

Can stopping save me money on South Carolina to Key West flights?

You could potentially save up to 77% on your flight if you consider stops on a South Carolina to Key West flight.

Cheap South Carolina to Key West flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Key West

Best Price Found	$60
Fastest flight time	2h 18m
Direct flights	Every day
Airports in Key West	1 airport

The best one-way flight to Key West from South Carolina in the past 72 hours is $60. The best round-trip flight deal from South Carolina to Key West found on momondo in the last 72 hours is $105.

The fastest flight from South Carolina to Key West takes 2h 18m

Direct flights go from South Carolina to Key West every day.

There is 1 airport in Key West. From South Carolina there are direct flights to Key West (EYW).

Search flight deals

Frequently asked questions about flying from South Carolina to Key West

When did momondo last update prices for flights from South Carolina to Key West Airport?
Prices for flights from South Carolina to Key West Airport are refreshed on a daily basis.
How many operators does momondo search for flights from South Carolina to Key West Airport?
There are 4 operators available for flights from South Carolina to Key West Airport as of September 2026.
How old do you have to be to fly from South Carolina to Key West Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to Key West Airport.
What documentation or ID do you need to fly to Key West Airport?
The required travel and health documents for your Key West Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Key West Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from South Carolina to Key West

Compare and see reviews for airlines that fly from South Carolina to Key West with momondo

Airline	Rating	Free Cancellation	Price
Allegiant Air	PriceFrom $76	Free Cancellation	Rating 7.3 677 reviews	Search Allegiant Air flights
Breeze Airways	PriceFrom $104	Free Cancellation	Rating 8.2 320 reviews	Search Breeze Airways flights
Delta	PriceFrom $125	Free Cancellation	Rating 7.8 8,548 reviews	Search Delta flights
American Airlines	PriceFrom $268	Free Cancellation	Rating 7.1 12,042 reviews	Search American Airlines flights

Big Pine Key

Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Key West?

It is quick and easy to find South Carolina to Key West flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Key West that suits you.

Can I find flights from South Carolina to Key West with flexible booking policies on momondo?

Yes. All flights to Key West from South Carolina on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from South Carolina to Key West?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Key West from South Carolina.

I’m not ready to book a flight from South Carolina to Key West right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Key West, momondo offers a useful price alert feature which will track prices for flights to Key West from South Carolina and alert you when they change.

An easier way to manage your Key West trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Start using Trips

Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

1 adult

Wed 10/7

Wed 10/14

Email me momondo's favorite deals

By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States

Nearby airports

Airlines

Cabin classes

Other United States destinations

Other flights from South Carolina

Complete your trip

Feeling lucky

Cheap flights from South Carolina to Key West from $60

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Key West departing on 9/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

Find the cheapest flights from South Carolina to Key West

Cheap round-trip flights

Cheap one-way flights

Cheap last minute flights

Cheap direct flights

Big names and deals

Big names and deals

Filter for what you want

Filter for what you want

Trusted and free

Trusted and free

Price Alerts

Price Alerts

Breeze Airways flights from South Carolina to Key West

Our best Breeze Airways deals on South Carolina to Key West flight tickets

Delta flights from South Carolina to Key West

Our best Delta deals on South Carolina to Key West flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from South Carolina to Key West that are best for you.

See travel insights to Key West from

How to get the cheapest flight ticket from South Carolina to Key West

What is the cheapest month to fly to Key West?

Can stopping save me money on South Carolina to Key West flights?

What is the cheapest airline that flies from South Carolina to Key West?

What airlines fly to Key West?

How many flights depart from South Carolina to Key West on average per week?

How long does it take to fly to Key West?

Cheap South Carolina to Key West flight deals and tips

Best Price Found

Fastest flight time

Direct flights

Airports in Key West

Frequently asked questions about flying from South Carolina to Key West

Best airlines flying from South Carolina to Key West

Compare and see reviews for airlines that fly from South Carolina to Key West with momondo

Traveling to a place near Key West?

Why use momondo?

An easier way to manage your Key West trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing Florida

Fly your favorite airline to Key West

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Cabin classes currently available on flights to Key West

List of cabin classes available on flights landing in Key West. Availability may vary depending on flight origin and airline.

Popular cities in the United States

Popular flights according to clicks in the last 7 days on momondo

Fly to other destinations from South Carolina

According to popular flight searches on momondo this year

Complete your trip to Key West

Explore popular destinations other users love

According to popular flight searches on momondo this year