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Cheap flights from South Carolina to Columbia from $180

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Columbia departing on 9/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from South Carolina to Columbia

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
12:44 pm - 5:52 pm
CHS
-
COU
6h 08m
1 stop
American Airlines Logo
7:20 am - 2:41 pm
COU
-
CHS
6h 21m
1 stop
$328American Airlines
Sat, Jul 11 - Wed, Jul 15
American Airlines Logo
8:40 pm - 9:52 pm
CLT
-
COU
2h 12mnonstop
American Airlines Logo
7:30 am - 10:45 am
COU
-
CLT
2h 15mnonstop
$373American Airlines
Wed, Jul 29 - Wed, Aug 5
United Airlines Logo
6:30 am - 10:16 am
CHS
-
COU
4h 46m
1 stop
United Airlines Logo
3:11 pm - 9:34 pm
COU
-
CHS
5h 23m
1 stop
$378United Airlines
Sat, Aug 22 - Tue, Aug 25
American Airlines Logo
7:42 am - 12:13 pm
CLT
-
COU
5h 31m
1 stop
American Airlines Logo
7:30 am - 10:45 am
COU
-
CLT
2h 15mnonstop
$382American Airlines
Wed, Aug 5 - Wed, Aug 12
United Airlines Logo
6:30 am - 10:16 am
CHS
-
COU
4h 46m
1 stop
United Airlines Logo
10:55 am - 11:59 pm
COU
-
CHS
12h 04m
2 stops
$384United Airlines
Sat, Aug 22 - Tue, Aug 25
United Airlines Logo
10:14 am - 8:59 pm
CHS
-
COU
11h 45m
2 stops
United Airlines Logo
10:55 am - 11:59 pm
COU
-
CHS
12h 04m
2 stops
$389United Airlines
Sat, Aug 22 - Tue, Aug 25
American Airlines Logo
1:06 pm - 6:03 pm
CLT
-
COU
5h 57m
1 stop
American Airlines Logo
6:00 am - 12:03 pm
COU
-
CLT
5h 03m
1 stop
$392American Airlines
Wed, Aug 5 - Wed, Aug 12
United Airlines Logo
8:05 am - 2:50 pm
CLT
-
COU
7h 45m
1 stop
United Airlines Logo
6:15 am - 4:55 pm
COU
-
CLT
9h 40m
2 stops
$398United Airlines
Wed, Aug 5 - Wed, Aug 12
United Airlines Logo
6:00 am - 2:50 pm
CLT
-
COU
9h 50m
2 stops
United Airlines Logo
6:15 am - 3:18 pm
COU
-
CLT
8h 03m
2 stops
$403United Airlines
Wed, Aug 5 - Wed, Aug 12
American Airlines Logo
6:06 am - 10:01 am
CAE
-
COU
4h 55m
1 stop
American Airlines Logo
10:32 am - 7:08 pm
COU
-
CAE
7h 36m
2 stops
$405American Airlines
Tue, Jul 21 - Tue, Jul 28

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American Airlines flights from South Carolina to Columbia, Missouri

Our best American Airlines deals on South Carolina to Columbia, Missouri flight tickets
American Airlines
Jul 11
CHS12:44 pmCharleston
6h 08m
1 stop
COU5:52 pmColumbia Regional
Jul 15
COU7:20 amColumbia Regional
6h 21m
1 stop
CHS2:41 pmCharleston
$328
American Airlines
Jul 29
CLT8:40 pmCharlotte Douglas
2h 12m
COU9:52 pmColumbia Regional
Aug 5
COU7:30 amColumbia Regional
2h 15m
CLT10:45 amCharlotte Douglas
$373
American Airlines
Aug 5
CLT7:42 amCharlotte Douglas
5h 31m
1 stop
COU12:13 pmColumbia Regional
Aug 12
COU7:30 amColumbia Regional
2h 15m
CLT10:45 amCharlotte Douglas
$382

United Airlines flights from South Carolina to Columbia, Missouri

Our best United Airlines deals on South Carolina to Columbia, Missouri flight tickets
United Airlines
Aug 22
CHS4:28 pmCharleston
7h 27m
1 stop
COU10:55 pmColumbia Regional
Aug 25
COU3:11 pmColumbia Regional
5h 23m
1 stop
CHS9:34 pmCharleston
$378
United Airlines
Aug 22
CHS6:30 amCharleston
4h 46m
1 stop
COU10:16 amColumbia Regional
Aug 25
COU10:55 amColumbia Regional
12h 04m
2 stops
CHS11:59 pmCharleston
$384
United Airlines
Aug 22
CHS10:14 amCharleston
11h 45m
2 stops
COU8:59 pmColumbia Regional
Aug 25
COU10:55 amColumbia Regional
12h 04m
2 stops
CHS11:59 pmCharleston
$389

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Columbia, Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 27, 2026.
Use the filters below to find and compare flights from South Carolina to Columbia, Missouri that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlestonColumbia

CHS - COU

CHSCOU

Charleston

Sat 7/11

12:44 pm-5:52 pm

1 stop6h 08m

Columbia Regional

Wed 7/15

7:20 am-2:41 pm

1 stop6h 21m

$328
Quickest round-trip

CharlotteColumbia

CLT - COU

CLTCOU

Charlotte Douglas

Wed 7/29

8:40 pm-9:52 pm

Nonstop2h 12m

Columbia Regional

Wed 8/5

7:30 am-10:45 am

Nonstop2h 15m

$373

CharlestonColumbia

CHS - COU

CHSCOU

Charleston

Sat 8/22

6:30 am-10:16 am

1 stop4h 46m

Columbia Regional

Tue 8/25

3:11 pm-9:34 pm

1 stop5h 23m

$378

CharlotteColumbia

CLT - COU

CLTCOU

Charlotte Douglas

Wed 8/5

7:42 am-12:13 pm

1 stop5h 31m

Columbia Regional

Wed 8/12

7:30 am-10:45 am

Nonstop2h 15m

$382

CharlestonColumbia

CHS - COU

CHSCOU

Charleston

Sat 8/22

6:30 am-10:16 am

1 stop4h 46m

Columbia Regional

Tue 8/25

10:55 am-11:59 pm

2 stops12h 04m

$384

CharlestonColumbia

CHS - COU

CHSCOU

Charleston

Sat 8/22

10:14 am-8:59 pm

2 stops11h 45m

Columbia Regional

Tue 8/25

10:55 am-11:59 pm

2 stops12h 04m

$389

CharlotteColumbia

CLT - COU

CLTCOU

Charlotte Douglas

Wed 8/5

1:06 pm-6:03 pm

1 stop5h 57m

Columbia Regional

Wed 8/12

6:00 am-12:03 pm

1 stop5h 03m

$392

CharlotteColumbia

CLT - COU

CLTCOU

Charlotte Douglas

Wed 8/5

8:05 am-2:50 pm

1 stop7h 45m

Columbia Regional

Wed 8/12

6:15 am-4:55 pm

2 stops9h 40m

$398

CharlotteColumbia

CLT - COU

CLTCOU

Charlotte Douglas

Wed 8/5

6:00 am-2:50 pm

2 stops9h 50m

Columbia Regional

Wed 8/12

6:15 am-3:18 pm

2 stops8h 03m

$403

ColumbiaColumbia

CAE - COU

CAECOU

Columbia Metropolitan

Tue 7/21

6:06 am-10:01 am

1 stop4h 55m

Columbia Regional

Tue 7/28

10:32 am-7:08 pm

2 stops7h 36m

$405

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Columbia from

How to get the cheapest flight ticket from South Carolina to Columbia, Missouri

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on South Carolina to Columbia, Missouri flights?

You could potentially save up to 24% on your flight if you consider stops on a South Carolina to Columbia, Missouri flight.

Cheap South Carolina to Columbia, Missouri flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Columbia, Missouri

Fastest flight time

2h 14m

Direct flights

Mon, Wed, Thu, Fri and Sun

Airports in Columbia, Missouri

1 airport
The fastest flight from South Carolina to Columbia, Missouri takes 2h 14m
Direct flights go from South Carolina to Columbia, Missouri on Monday, Wednesday, Thursday, Friday and Sunday. There are no airlines offering direct flights.
There is 1 airport in Columbia, Missouri. From South Carolina there are direct flights to Columbia Regional (COU).
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Frequently asked questions about flying from South Carolina to Columbia, Missouri

  • When did momondo last update prices for flights from South Carolina to Columbia Regional Airport?

    Prices for flights from South Carolina to Columbia Regional Airport are updated daily.

  • How many operators does momondo search for flights from South Carolina to Columbia Regional Airport?

  • How old do you have to be to fly from South Carolina to Columbia Regional Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from South Carolina to Columbia Regional Airport.

  • What documentation or ID do you need to fly to Columbia Regional Airport?

    The travel and health documents you'll need for your trip to Columbia Regional Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Columbia Regional Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from South Carolina to Columbia, Missouri

Compare and see reviews for airlines that fly from South Carolina to Columbia, Missouri with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $308Free CancellationRating
7.1
11,777 reviews
Search American Airlines flights

Traveling to a place near Columbia?

Book flights to Columbia if you plan to visit one of these locations
Jefferson City
Sedalia
Moberly
Lincoln

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Columbia?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from South Carolina to Columbia. momondo saves you time and could save you money on your trip.

Can I find flights from South Carolina to Columbia with flexible booking policies on momondo?

All flight searches from South Carolina to Columbia on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from South Carolina to Columbia?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Columbia from South Carolina.

I’m not ready to book a flight from South Carolina to Columbia right now. Can momondo alert me if prices change?

Price alerts on flights to Columbia from South Carolina are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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