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Cheap flights from South Carolina to Columbia from $223

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Columbia departing on 3/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
6:00 am - 10:33 am
CLT
-
COU
5h 33m
1 stop
United Airlines Logo
11:15 am - 5:24 pm
COU
-
CLT
5h 09m
1 stop
$268United Airlines
Sat, Feb 21 - Wed, Feb 25
United Airlines Logo
5:25 pm - 9:33 pm
CLT
-
COU
5h 08m
1 stop
United Airlines Logo
11:15 am - 9:09 pm
COU
-
CLT
8h 54m
2 stops
$274United Airlines
Sat, Feb 21 - Wed, Feb 25
United Airlines Logo
5:05 pm - 9:33 pm
CHS
-
COU
5h 28m
1 stop
United Airlines Logo
8:00 am - 1:52 pm
COU
-
CHS
4h 52m
1 stop
$298United Airlines
Tue, Feb 24 - Sat, Feb 28
United Airlines Logo
6:00 am - 2:28 pm
CHS
-
COU
9h 28m
2 stops
United Airlines Logo
8:00 am - 1:52 pm
COU
-
CHS
4h 52m
1 stop
$304United Airlines
Tue, Feb 24 - Sat, Feb 28
United Airlines Logo
6:00 am - 2:28 pm
CHS
-
COU
9h 28m
2 stops
United Airlines Logo
11:15 am - 11:44 pm
COU
-
CHS
11h 29m
2 stops
$309United Airlines
Tue, Feb 24 - Sat, Feb 28
United Airlines Logo
11:07 am - 9:33 pm
CLT
-
COU
11h 26m
2 stops
United Airlines Logo
11:15 am - 9:09 pm
COU
-
CLT
8h 54m
2 stops
$309United Airlines
Sat, Feb 21 - Wed, Feb 25
United Airlines Logo
3:32 pm - 9:33 pm
CAE
-
COU
7h 01m
1 stop
United Airlines Logo
3:10 pm - 11:44 pm
COU
-
CAE
7h 34m
2 stops
$325United Airlines
Tue, Feb 24 - Sat, Feb 28
United Airlines Logo
3:32 pm - 9:33 pm
CAE
-
COU
7h 01m
1 stop
United Airlines Logo
3:10 pm - 8:57 pm
COU
-
CAE
4h 47m
1 stop
$350United Airlines
Tue, Feb 24 - Sat, Feb 28
American Airlines Logo
9:22 pm - 10:37 pm
CLT
-
COU
2h 15mnonstop
American Airlines Logo
7:00 am - 10:15 am
COU
-
CLT
2h 15mnonstop
$403American Airlines
Thu, Jun 11 - Fri, Jun 19
American Airlines Logo
4:38 pm - 8:19 pm
CLT
-
COU
4h 41m
1 stop
American Airlines Logo
6:00 am - 11:15 am
COU
-
CLT
4h 15m
1 stop
$406American Airlines
Wed, Mar 25 - Wed, Apr 1

United Airlines flights from South Carolina to Columbia, Missouri

Our best United Airlines deals on South Carolina to Columbia, Missouri flight tickets
United Airlines
Feb 21
CLT6:00 amCharlotte Douglas
5h 33m
1 stop
COU10:33 amColumbia Regional
Feb 25
COU11:15 amColumbia Regional
5h 09m
1 stop
CLT5:24 pmCharlotte Douglas
$268
United Airlines
Feb 21
CLT5:25 pmCharlotte Douglas
5h 08m
1 stop
COU9:33 pmColumbia Regional
Feb 25
COU11:15 amColumbia Regional
8h 54m
2 stops
CLT9:09 pmCharlotte Douglas
$274
United Airlines
Feb 24
CHS5:05 pmCharleston
5h 28m
1 stop
COU9:33 pmColumbia Regional
Feb 28
COU8:00 amColumbia Regional
4h 52m
1 stop
CHS1:52 pmCharleston
$298

American Airlines flights from South Carolina to Columbia, Missouri

Our best American Airlines deals on South Carolina to Columbia, Missouri flight tickets
American Airlines
Jun 11
CLT9:22 pmCharlotte Douglas
2h 15m
COU10:37 pmColumbia Regional
Jun 19
COU7:00 amColumbia Regional
2h 15m
CLT10:15 amCharlotte Douglas
$403
American Airlines
Mar 25
CLT4:38 pmCharlotte Douglas
4h 41m
1 stop
COU8:19 pmColumbia Regional
Apr 1
COU6:00 amColumbia Regional
4h 15m
1 stop
CLT11:15 amCharlotte Douglas
$406
American Airlines
Mar 13
CLT2:05 pmCharlotte Douglas
4h 55m
1 stop
COU6:00 pmColumbia Regional
Mar 15
COU5:39 pmColumbia Regional
5h 46m
1 stop
CLT12:25 amCharlotte Douglas
$422

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Columbia, Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 9, 2026.
Use the filters below to find and compare flights from South Carolina to Columbia, Missouri that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlotteColumbia

CLT - COU

CLTCOU

Charlotte Douglas

Sat 2/21

6:00 am-10:33 am

1 stop5h 33m

Columbia Regional

Wed 2/25

11:15 am-5:24 pm

1 stop5h 09m

$268

CharlotteColumbia

CLT - COU

CLTCOU

Charlotte Douglas

Sat 2/21

5:25 pm-9:33 pm

1 stop5h 08m

Columbia Regional

Wed 2/25

11:15 am-9:09 pm

2 stops8h 54m

$274

CharlestonColumbia

CHS - COU

CHSCOU

Charleston

Tue 2/24

5:05 pm-9:33 pm

1 stop5h 28m

Columbia Regional

Sat 2/28

8:00 am-1:52 pm

1 stop4h 52m

$298

CharlestonColumbia

CHS - COU

CHSCOU

Charleston

Tue 2/24

6:00 am-2:28 pm

2 stops9h 28m

Columbia Regional

Sat 2/28

8:00 am-1:52 pm

1 stop4h 52m

$304

CharlestonColumbia

CHS - COU

CHSCOU

Charleston

Tue 2/24

6:00 am-2:28 pm

2 stops9h 28m

Columbia Regional

Sat 2/28

11:15 am-11:44 pm

2 stops11h 29m

$309

CharlotteColumbia

CLT - COU

CLTCOU

Charlotte Douglas

Sat 2/21

11:07 am-9:33 pm

2 stops11h 26m

Columbia Regional

Wed 2/25

11:15 am-9:09 pm

2 stops8h 54m

$309

ColumbiaColumbia

CAE - COU

CAECOU

Columbia Metropolitan

Tue 2/24

3:32 pm-9:33 pm

1 stop7h 01m

Columbia Regional

Sat 2/28

3:10 pm-11:44 pm

2 stops7h 34m

$325

ColumbiaColumbia

CAE - COU

CAECOU

Columbia Metropolitan

Tue 2/24

3:32 pm-9:33 pm

1 stop7h 01m

Columbia Regional

Sat 2/28

3:10 pm-8:57 pm

1 stop4h 47m

$350

CharlotteColumbia

CLT - COU

CLTCOU

Charlotte Douglas

Thu 6/11

9:22 pm-10:37 pm

Nonstop2h 15m

Columbia Regional

Fri 6/19

7:00 am-10:15 am

Nonstop2h 15m

$403

CharlotteColumbia

CLT - COU

CLTCOU

Charlotte Douglas

Wed 3/25

4:38 pm-8:19 pm

1 stop4h 41m

Columbia Regional

Wed 4/1

6:00 am-11:15 am

1 stop4h 15m

$406

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Columbia from

How to get the cheapest flight ticket from South Carolina to Columbia, Missouri

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on South Carolina to Columbia, Missouri flights?

You could potentially save up to 4% on your flight if you consider stops on a South Carolina to Columbia, Missouri flight.

Cheap South Carolina to Columbia, Missouri flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Columbia, Missouri

Fastest flight time

4h 47m

Direct flights

Mon, Tue, Wed and Fri

Airports in Columbia, Missouri

1 airport
The fastest flight from South Carolina to Columbia, Missouri takes 4h 47m
Direct flights go from South Carolina to Columbia, Missouri on Monday, Tuesday, Wednesday and Friday. There are no airlines offering direct flights.
There is 1 airport in Columbia, Missouri. From South Carolina there are direct flights to Columbia Regional (COU).
Search flight deals

  • When did momondo last update prices for flights from South Carolina to Columbia Regional Airport?

    Prices for flights from South Carolina to Columbia Regional Airport are updated daily.

  • How old do you have to be to fly from South Carolina to Columbia Regional Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from South Carolina to Columbia Regional Airport.

  • What documentation or ID do you need to fly to Columbia Regional Airport?

    The travel and health documents you'll need for your trip to Columbia Regional Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Columbia Regional Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Columbia?

Book flights to Columbia if you plan to visit one of these locations
Jefferson City
Sedalia
Moberly
Lincoln

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Columbia?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from South Carolina to Columbia. momondo saves you time and could save you money on your trip.

Can I find flights from South Carolina to Columbia with flexible booking policies on momondo?

All flight searches from South Carolina to Columbia on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from South Carolina to Columbia?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Columbia from South Carolina.

I’m not ready to book a flight from South Carolina to Columbia right now. Can momondo alert me if prices change?

Price alerts on flights to Columbia from South Carolina are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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