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Cheap flights from South Carolina to Columbia from $221

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Columbia departing on 6/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from South Carolina to Columbia

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
6:30 pm - 11:06 pm
CHS
-
COU
5h 36m
1 stop
United Airlines Logo
3:05 pm - 9:51 pm
COU
-
CHS
5h 46m
1 stop
$318United Airlines
Wed, May 27 - Sat, May 30
United Airlines Logo
6:00 am - 2:30 pm
CHS
-
COU
9h 30m
2 stops
United Airlines Logo
3:05 pm - 9:51 pm
COU
-
CHS
5h 46m
1 stop
$324United Airlines
Wed, May 27 - Sat, May 30
American Airlines Logo
7:00 am - 11:35 am
CAE
-
COU
5h 35m
1 stop
American Airlines Logo
10:16 am - 8:21 pm
COU
-
CAE
9h 05m
2 stops
$334American Airlines
Sat, Apr 11 - Wed, Apr 15
American Airlines Logo
2:43 pm - 9:30 pm
CAE
-
COU
7h 47m
2 stops
American Airlines Logo
6:00 am - 4:51 pm
COU
-
CAE
9h 51m
2 stops
$339American Airlines
Sat, Apr 11 - Wed, Apr 15
American Airlines Logo
5:18 pm - 9:29 pm
CAE
-
COU
5h 11m
1 stop
American Airlines Logo
7:16 am - 2:05 pm
COU
-
CAE
5h 49m
1 stop
$353American Airlines
Wed, Jun 3 - Wed, Jun 10
United Airlines Logo
6:25 am - 10:48 am
CAE
-
COU
5h 23m
1 stop
United Airlines Logo
5:00 am - 2:16 pm
COU
-
CAE
8h 16m
2 stops
$359United Airlines
Wed, Jun 3 - Wed, Jun 10
United Airlines Logo
2:51 pm - 9:59 pm
CAE
-
COU
8h 08m
2 stops
United Airlines Logo
5:00 am - 2:16 pm
COU
-
CAE
8h 16m
2 stops
$389United Airlines
Wed, Jun 3 - Wed, Jun 10
United Airlines Logo
6:00 am - 2:30 pm
CHS
-
COU
9h 30m
2 stops
United Airlines Logo
11:23 am - 11:56 pm
COU
-
CHS
11h 33m
2 stops
$399United Airlines
Wed, May 27 - Sat, May 30
United Airlines Logo
6:00 am - 10:55 am
CHS
-
COU
5h 55m
1 stop
United Airlines Logo
3:23 pm - 11:33 pm
COU
-
CHS
7h 10m
1 stop
$402United Airlines
Fri, Apr 10 - Sun, Apr 12
American Airlines Logo
5:18 pm - 9:29 pm
CAE
-
COU
5h 11m
1 stop
American Airlines Logo
10:30 am - 4:48 pm
COU
-
CAE
5h 18m
1 stop
$409American Airlines
Tue, Jun 9 - Tue, Jun 23

American Airlines flights from South Carolina to Columbia, Missouri

Our best American Airlines deals on South Carolina to Columbia, Missouri flight tickets
American Airlines
Apr 11
CAE7:00 amColumbia Metropolitan
5h 35m
1 stop
COU11:35 amColumbia Regional
Apr 15
COU10:16 amColumbia Regional
9h 05m
2 stops
CAE8:21 pmColumbia Metropolitan
$334
American Airlines
Apr 11
CAE2:43 pmColumbia Metropolitan
7h 47m
2 stops
COU9:30 pmColumbia Regional
Apr 15
COU6:00 amColumbia Regional
9h 51m
2 stops
CAE4:51 pmColumbia Metropolitan
$339
American Airlines
Jun 3
CAE5:18 pmColumbia Metropolitan
5h 11m
1 stop
COU9:29 pmColumbia Regional
Jun 10
COU7:16 amColumbia Regional
5h 49m
1 stop
CAE2:05 pmColumbia Metropolitan
$353

United Airlines flights from South Carolina to Columbia, Missouri

Our best United Airlines deals on South Carolina to Columbia, Missouri flight tickets
United Airlines
May 27
CHS6:30 pmCharleston
5h 36m
1 stop
COU11:06 pmColumbia Regional
May 30
COU3:05 pmColumbia Regional
5h 46m
1 stop
CHS9:51 pmCharleston
$318
United Airlines
May 27
CHS6:00 amCharleston
9h 30m
2 stops
COU2:30 pmColumbia Regional
May 30
COU3:05 pmColumbia Regional
5h 46m
1 stop
CHS9:51 pmCharleston
$324
United Airlines
Jun 3
CAE6:25 amColumbia Metropolitan
5h 23m
1 stop
COU10:48 amColumbia Regional
Jun 10
COU5:00 amColumbia Regional
8h 16m
2 stops
CAE2:16 pmColumbia Metropolitan
$359

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Columbia, Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 31, 2026.
Use the filters below to find and compare flights from South Carolina to Columbia, Missouri that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlestonColumbia

CHS - COU

CHSCOU

Charleston

Wed 5/27

6:30 pm-11:06 pm

1 stop5h 36m

Columbia Regional

Sat 5/30

3:05 pm-9:51 pm

1 stop5h 46m

$318

CharlestonColumbia

CHS - COU

CHSCOU

Charleston

Wed 5/27

6:00 am-2:30 pm

2 stops9h 30m

Columbia Regional

Sat 5/30

3:05 pm-9:51 pm

1 stop5h 46m

$324

ColumbiaColumbia

CAE - COU

CAECOU

Columbia Metropolitan

Sat 4/11

7:00 am-11:35 am

1 stop5h 35m

Columbia Regional

Wed 4/15

10:16 am-8:21 pm

2 stops9h 05m

$334

ColumbiaColumbia

CAE - COU

CAECOU

Columbia Metropolitan

Sat 4/11

2:43 pm-9:30 pm

2 stops7h 47m

Columbia Regional

Wed 4/15

6:00 am-4:51 pm

2 stops9h 51m

$339

ColumbiaColumbia

CAE - COU

CAECOU

Columbia Metropolitan

Wed 6/3

5:18 pm-9:29 pm

1 stop5h 11m

Columbia Regional

Wed 6/10

7:16 am-2:05 pm

1 stop5h 49m

$353

ColumbiaColumbia

CAE - COU

CAECOU

Columbia Metropolitan

Wed 6/3

6:25 am-10:48 am

1 stop5h 23m

Columbia Regional

Wed 6/10

5:00 am-2:16 pm

2 stops8h 16m

$359

ColumbiaColumbia

CAE - COU

CAECOU

Columbia Metropolitan

Wed 6/3

2:51 pm-9:59 pm

2 stops8h 08m

Columbia Regional

Wed 6/10

5:00 am-2:16 pm

2 stops8h 16m

$389

CharlestonColumbia

CHS - COU

CHSCOU

Charleston

Wed 5/27

6:00 am-2:30 pm

2 stops9h 30m

Columbia Regional

Sat 5/30

11:23 am-11:56 pm

2 stops11h 33m

$399

CharlestonColumbia

CHS - COU

CHSCOU

Charleston

Fri 4/10

6:00 am-10:55 am

1 stop5h 55m

Columbia Regional

Sun 4/12

3:23 pm-11:33 pm

1 stop7h 10m

$402
Quickest round-trip

ColumbiaColumbia

CAE - COU

CAECOU

Columbia Metropolitan

Tue 6/9

5:18 pm-9:29 pm

1 stop5h 11m

Columbia Regional

Tue 6/23

10:30 am-4:48 pm

1 stop5h 18m

$409

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Columbia from

How to get the cheapest flight ticket from South Carolina to Columbia, Missouri

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on South Carolina to Columbia, Missouri flights?

You could potentially save up to 41% on your flight if you consider stops on a South Carolina to Columbia, Missouri flight.

Cheap South Carolina to Columbia, Missouri flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Columbia, Missouri

Fastest flight time

5h 19m

Direct flights

Mon, Wed, Thu, Fri and Sat

Airports in Columbia, Missouri

1 airport
The fastest flight from South Carolina to Columbia, Missouri takes 5h 19m
Direct flights go from South Carolina to Columbia, Missouri on Monday, Wednesday, Thursday, Friday and Saturday. There are no airlines offering direct flights.
There is 1 airport in Columbia, Missouri. From South Carolina there are direct flights to Columbia Regional (COU).
Search flight deals

  • When did momondo last update prices for flights from South Carolina to Columbia Regional Airport?

    Prices for flights from South Carolina to Columbia Regional Airport are updated daily.

  • How old do you have to be to fly from South Carolina to Columbia Regional Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from South Carolina to Columbia Regional Airport.

  • What documentation or ID do you need to fly to Columbia Regional Airport?

    The travel and health documents you'll need for your trip to Columbia Regional Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Columbia Regional Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Columbia?

Book flights to Columbia if you plan to visit one of these locations
Jefferson City
Sedalia
Moberly
Lincoln

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Columbia?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from South Carolina to Columbia. momondo saves you time and could save you money on your trip.

Can I find flights from South Carolina to Columbia with flexible booking policies on momondo?

All flight searches from South Carolina to Columbia on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from South Carolina to Columbia?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Columbia from South Carolina.

I’m not ready to book a flight from South Carolina to Columbia right now. Can momondo alert me if prices change?

Price alerts on flights to Columbia from South Carolina are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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