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Cheap flights from South Carolina to Columbia from $328

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Columbia departing on 11/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

American Airlines Logo
6:08 pm - 10:45 pmCLT-COU
5h 37m1 stop
American Airlines Logo
6:24 am - 1:04 pmCOU-CLT
5h 40m1 stop
$400American Airlines
Find Deal
Fri, Sep 26 - Wed, Oct 1
United Airlines Logo
7:46 pm - 9:27 pmCLT-COU
26h 41m2 stops
United Airlines Logo
8:00 am - 9:41 pmCOU-CLT
12h 41m1 stop
$443United Airlines
Find Deal
Fri, Sep 26 - Wed, Oct 1
United Airlines Logo
7:46 pm - 9:27 pmCLT-COU
26h 41m2 stops
United Airlines Logo
8:00 am - 2:10 pmCOU-CLT
29h 10m2 stops
$465United Airlines
Find Deal
Fri, Sep 26 - Wed, Oct 1
American Airlines Logo
7:06 am - 11:47 amCHS-COU
5h 41m1 stop
American Airlines Logo
6:15 am - 1:17 pmCOU-CHS
6h 02m1 stop
$469American Airlines
Find Deal
Wed, Aug 20 - Sun, Aug 24
American Airlines Logo
10:20 am - 4:44 pmCLT-COU
7h 24m1 stop
American Airlines Logo
5:16 pm - 11:55 pmCOU-CLT
5h 39m1 stop
$470American Airlines
Find Deal
Fri, Sep 19 - Sun, Sep 21
American Airlines Logo
3:23 pm - 10:49 pmCAE-COU
8h 26m1 stop
American Airlines Logo
6:15 am - 2:49 pmCOU-CAE
7h 34m2 stops
$475American Airlines
Find Deal
Fri, Aug 22 - Tue, Aug 26
American Airlines Logo
5:38 am - 4:38 pmCHS-COU
12h 00m2 stops
American Airlines Logo
7:27 am - 1:50 pmCOU-CHS
5h 23m1 stop
$475American Airlines
Find Deal
Wed, Aug 20 - Sun, Aug 24
American Airlines Logo
4:35 pm - 9:54 pmCLT-COU
6h 19m1 stop
American Airlines Logo
6:24 am - 3:04 pmCOU-CLT
7h 40m2 stops
$475American Airlines
Find Deal
Thu, Sep 25 - Wed, Oct 1
American Airlines Logo
10:20 am - 4:44 pmCLT-COU
7h 24m2 stops
American Airlines Logo
4:23 pm - 10:38 pmCOU-CLT
5h 15m1 stop
$476American Airlines
Find Deal
Fri, Sep 19 - Sun, Sep 21
American Airlines Logo
3:29 pm - 9:33 pmCAE-COU
7h 04m2 stops
American Airlines Logo
6:15 am - 2:49 pmCOU-CAE
7h 34m2 stops
$480American Airlines
Find Deal
Fri, Aug 22 - Tue, Aug 26

American Airlines flights from South Carolina to Columbia, Missouri

Our best American Airlines deals on South Carolina to Columbia, Missouri flight tickets
American Airlines
Sep 26
CLT6:08 pmCharlotte Douglas
5h 37m
1 stop
COU10:45 pmColumbia Regional
Oct 1
COU6:24 amColumbia Regional
5h 40m
1 stop
CLT1:04 pmCharlotte Douglas
$400
Find similar
American Airlines
Aug 20
CHS7:06 amCharleston
5h 41m
1 stop
COU11:47 amColumbia Regional
Aug 24
COU6:15 amColumbia Regional
6h 02m
1 stop
CHS1:17 pmCharleston
$469
Find similar
American Airlines
Sep 19
CLT10:20 amCharlotte Douglas
7h 24m
1 stop
COU4:44 pmColumbia Regional
Sep 21
COU5:16 pmColumbia Regional
5h 39m
1 stop
CLT11:55 pmCharlotte Douglas
$470
Find similar

United Airlines flights from South Carolina to Columbia, Missouri

Our best United Airlines deals on South Carolina to Columbia, Missouri flight tickets
United Airlines
Sep 26
CLT7:46 pmCharlotte Douglas
26h 41m
2 stops
COU9:27 pmColumbia Regional
Oct 1
COU8:00 amColumbia Regional
12h 41m
1 stop
CLT9:41 pmCharlotte Douglas
$443
Find similar
United Airlines
Sep 26
CLT7:46 pmCharlotte Douglas
26h 41m
2 stops
COU9:27 pmColumbia Regional
Oct 1
COU8:00 amColumbia Regional
29h 10m
2 stops
CLT2:10 pmCharlotte Douglas
$465
Find similar
United Airlines
Sep 26
CAE11:04 amColumbia Metropolitan
11h 23m
1 stop
COU9:27 pmColumbia Regional
Sep 30
COU2:52 pmColumbia Regional
22h 26m
2 stops
CAE2:18 pmColumbia Metropolitan
$592
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Columbia, Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 7, 2025.
Use the filters below to find and compare flights from South Carolina to Columbia, Missouri that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlotteColumbia

CLT - COU

CLTCOU

Charlotte Douglas

Fri 9/26

6:08 pm-10:45 pm

1 stop5h 37m

Columbia Regional

Wed 10/1

6:24 am-1:04 pm

1 stop5h 40m

$400

CharlotteColumbia

CLT - COU

CLTCOU

Charlotte Douglas

Fri 9/26

7:46 pm-9:27 pm

2 stops26h 41m

Columbia Regional

Wed 10/1

8:00 am-9:41 pm

1 stop12h 41m

$443

CharlotteColumbia

CLT - COU

CLTCOU

Charlotte Douglas

Fri 9/26

7:46 pm-9:27 pm

2 stops26h 41m

Columbia Regional

Wed 10/1

8:00 am-2:10 pm

2 stops29h 10m

$465

CharlestonColumbia

CHS - COU

CHSCOU

Charleston

Wed 8/20

7:06 am-11:47 am

1 stop5h 41m

Columbia Regional

Sun 8/24

6:15 am-1:17 pm

1 stop6h 02m

$469

CharlotteColumbia

CLT - COU

CLTCOU

Charlotte Douglas

Fri 9/19

10:20 am-4:44 pm

1 stop7h 24m

Columbia Regional

Sun 9/21

5:16 pm-11:55 pm

1 stop5h 39m

$470

ColumbiaColumbia

CAE - COU

CAECOU

Columbia Metropolitan

Fri 8/22

3:23 pm-10:49 pm

1 stop8h 26m

Columbia Regional

Tue 8/26

6:15 am-2:49 pm

2 stops7h 34m

$475

CharlestonColumbia

CHS - COU

CHSCOU

Charleston

Wed 8/20

5:38 am-4:38 pm

2 stops12h 00m

Columbia Regional

Sun 8/24

7:27 am-1:50 pm

1 stop5h 23m

$475

CharlotteColumbia

CLT - COU

CLTCOU

Charlotte Douglas

Thu 9/25

4:35 pm-9:54 pm

1 stop6h 19m

Columbia Regional

Wed 10/1

6:24 am-3:04 pm

2 stops7h 40m

$475

CharlotteColumbia

CLT - COU

CLTCOU

Charlotte Douglas

Fri 9/19

10:20 am-4:44 pm

2 stops7h 24m

Columbia Regional

Sun 9/21

4:23 pm-10:38 pm

1 stop5h 15m

$476

ColumbiaColumbia

CAE - COU

CAECOU

Columbia Metropolitan

Fri 8/22

3:29 pm-9:33 pm

2 stops7h 04m

Columbia Regional

Tue 8/26

6:15 am-2:49 pm

2 stops7h 34m

$480

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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See travel insights to Columbia from

How to get the cheapest flight ticket from South Carolina to Columbia, Missouri

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on South Carolina to Columbia, Missouri flights?

You could potentially save up to 35% on your flight if you consider stops on a South Carolina to Columbia, Missouri flight.

Cheap South Carolina to Columbia, Missouri flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Columbia, Missouri

Best Price Found

$328

Fastest flight time

5h 04m

Direct flights

None

Airports in Columbia, Missouri

1 airport
The best one-way flight to Columbia, Missouri from South Carolina in the past 72 hours is $328. The best round-trip flight deal from South Carolina to Columbia, Missouri found on momondo in the last 72 hours is $400.
The fastest flight from South Carolina to Columbia, Missouri takes 5h 04m
There are no direct flights from South Carolina to Columbia, Missouri. Popular non-direct routes for this connection are Charleston Airport - Columbia Regional Airport, Columbia Metropolitan Airport - Columbia Regional Airport and Charlotte Douglas Airport - Columbia Regional Airport.
There is 1 airport near Columbia, Missouri: Columbia Regional (COU)
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  • When did momondo last update prices for flights from South Carolina to Columbia Regional Airport?

    Prices for flights from South Carolina to Columbia Regional Airport are updated daily.

  • How many operators does momondo search for flights from South Carolina to Columbia Regional Airport?

  • How old do you have to be to fly from South Carolina to Columbia Regional Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from South Carolina to Columbia Regional Airport.

  • What documentation or ID do you need to fly to Columbia Regional Airport?

    The travel and health documents you'll need for your trip to Columbia Regional Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Columbia Regional Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Columbia?

Book flights to Columbia if you plan to visit one of these locations
Jefferson City
Sedalia
Moberly
Lincoln

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Columbia?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from South Carolina to Columbia. momondo saves you time and could save you money on your trip.

Can I find flights from South Carolina to Columbia with flexible booking policies on momondo?

All flight searches from South Carolina to Columbia on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from South Carolina to Columbia?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Columbia from South Carolina.

I’m not ready to book a flight from South Carolina to Columbia right now. Can momondo alert me if prices change?

Price alerts on flights to Columbia from South Carolina are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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