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Cheap flights from South Carolina to Columbia from $199

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Columbia departing on 10/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from South Carolina to Columbia

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
12:23 pm - 6:03 pmCHS  Charleston-COU Columbia Regional
6h 40m1 stop Chicago O'Hare Intl
American Airlines Logo
7:00 am - 2:42 pmCOU  Columbia Regional-CHS Charleston
6h 42m1 stop Dallas/Fort Worth
$323American Airlines
Thu, Aug 27 - Tue, Sep 1
American Airlines Logo
12:23 pm - 6:03 pmCHS  Charleston-COU Columbia Regional
6h 40m1 stop Chicago O'Hare Intl
American Airlines Logo
8:09 am - 1:16 pmCOU  Columbia Regional-CHS Charleston
4h 07m1 stop Charlotte Douglas
$338American Airlines
Thu, Aug 27 - Mon, Aug 31
United Airlines Logo
5:38 pm - 10:55 pmCAE  Columbia Metropolitan-COU Columbia Regional
6h 17m1 stop Chicago O'Hare Intl
United Airlines Logo
6:15 am - 2:21 pmCOU  Columbia Regional-CAE Columbia Metropolitan
7h 06m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl
$344United Airlines
Thu, Aug 27 - Mon, Aug 31
United Airlines Logo
11:10 am - 10:55 pmCHS  Charleston-COU Columbia Regional
12h 45m2 stops Newark Chicago O'Hare Intl
United Airlines Logo
6:15 am - 1:58 pmCOU  Columbia Regional-CHS Charleston
6h 43m1 stop Chicago O'Hare Intl
$344United Airlines
Thu, Aug 27 - Mon, Aug 31
United Airlines Logo
11:10 am - 10:55 pmCHS  Charleston-COU Columbia Regional
12h 45m2 stops Newark Chicago O'Hare Intl
United Airlines Logo
6:15 am - 7:10 pmCOU  Columbia Regional-CHS Charleston
11h 55m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl
$349United Airlines
Thu, Aug 27 - Mon, Aug 31
United Airlines Logo
6:30 am - 10:16 amCHS  Charleston-COU Columbia Regional
4h 46m1 stop Chicago O'Hare Intl
United Airlines Logo
10:55 am - 11:59 pmCOU  Columbia Regional-CHS Charleston
12h 04m2 stops Chicago O'Hare Intl Newark
$351United Airlines
Thu, Aug 27 - Tue, Sep 1
United Airlines Logo
2:54 pm - 10:55 pmCHS  Charleston-COU Columbia Regional
9h 01m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl
United Airlines Logo
10:55 am - 11:59 pmCOU  Columbia Regional-CHS Charleston
12h 04m2 stops Chicago O'Hare Intl Newark
$356United Airlines
Thu, Aug 27 - Tue, Sep 1
American Airlines Logo
8:34 pm - 9:53 pmCLT  Charlotte Douglas-COU Columbia Regional
2h 19mnonstop
American Airlines Logo
8:12 am - 11:25 amCOU  Columbia Regional-CLT Charlotte Douglas
2h 13mnonstop
$383American Airlines
Tue, Oct 27 - Tue, Nov 3
United Airlines Logo
5:38 pm - 10:55 pmCAE  Columbia Metropolitan-COU Columbia Regional
6h 17m1 stop Chicago O'Hare Intl
United Airlines Logo
3:11 pm - 9:13 pmCOU  Columbia Regional-CAE Columbia Metropolitan
5h 02m1 stop Chicago O'Hare Intl
$388United Airlines
Wed, Sep 9 - Sat, Sep 12
United Airlines Logo
5:25 pm - 9:33 pmCAE  Columbia Metropolitan-COU Columbia Regional
5h 08m1 stop Chicago O'Hare Intl
United Airlines Logo
3:16 pm - 9:16 pmCOU  Columbia Regional-CAE Columbia Metropolitan
5h 00m1 stop Chicago O'Hare Intl
$388United Airlines
Wed, Jan 13 - Sat, Jan 16

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American Airlines flights from South Carolina to Columbia, Missouri

Our best American Airlines deals on South Carolina to Columbia, Missouri flight tickets
American Airlines
Aug 27
CHS12:23 pmCharleston
6h 40m
1 stop
COU6:03 pmColumbia Regional
Sep 1
COU7:00 amColumbia Regional
6h 42m
1 stop
CHS2:42 pmCharleston
$323
American Airlines
Aug 27
CHS12:23 pmCharleston
6h 40m
1 stop
COU6:03 pmColumbia Regional
Aug 31
COU8:09 amColumbia Regional
4h 07m
1 stop
CHS1:16 pmCharleston
$338
American Airlines
Oct 27
CLT8:34 pmCharlotte Douglas
2h 19m
COU9:53 pmColumbia Regional
Nov 3
COU8:12 amColumbia Regional
2h 13m
CLT11:25 amCharlotte Douglas
$383

United Airlines flights from South Carolina to Columbia, Missouri

Our best United Airlines deals on South Carolina to Columbia, Missouri flight tickets
United Airlines
Aug 27
CAE5:38 pmColumbia Metropolitan
6h 17m
1 stop
COU10:55 pmColumbia Regional
Aug 31
COU6:15 amColumbia Regional
7h 06m
2 stops
CAE2:21 pmColumbia Metropolitan
$344
United Airlines
Aug 27
CHS11:10 amCharleston
12h 45m
2 stops
COU10:55 pmColumbia Regional
Aug 31
COU6:15 amColumbia Regional
11h 55m
2 stops
CHS7:10 pmCharleston
$349
United Airlines
Aug 27
CHS6:30 amCharleston
4h 46m
1 stop
COU10:16 amColumbia Regional
Sep 1
COU10:55 amColumbia Regional
12h 04m
2 stops
CHS11:59 pmCharleston
$351

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Columbia, Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 13, 2026.
Use the filters below to find and compare flights from South Carolina to Columbia, Missouri that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlestonColumbia

CHS Charleston - COU Columbia Regional

CHSCOU

Charleston

Thu 8/27

12:23 pm-6:03 pm

1 stop6h 40m

Columbia Regional

Tue 9/1

7:00 am-2:42 pm

1 stop6h 42m

$323

CharlestonColumbia

CHS Charleston - COU Columbia Regional

CHSCOU

Charleston

Thu 8/27

12:23 pm-6:03 pm

1 stop6h 40m

Columbia Regional

Mon 8/31

8:09 am-1:16 pm

1 stop4h 07m

$338

ColumbiaColumbia

CAE Columbia Metropolitan - COU Columbia Regional

CAECOU

Columbia Metropolitan

Thu 8/27

5:38 pm-10:55 pm

1 stop6h 17m

Columbia Regional

Mon 8/31

6:15 am-2:21 pm

2 stops7h 06m

$344

CharlestonColumbia

CHS Charleston - COU Columbia Regional

CHSCOU

Charleston

Thu 8/27

11:10 am-10:55 pm

2 stops12h 45m

Columbia Regional

Mon 8/31

6:15 am-1:58 pm

1 stop6h 43m

$344

CharlestonColumbia

CHS Charleston - COU Columbia Regional

CHSCOU

Charleston

Thu 8/27

11:10 am-10:55 pm

2 stops12h 45m

Columbia Regional

Mon 8/31

6:15 am-7:10 pm

2 stops11h 55m

$349

CharlestonColumbia

CHS Charleston - COU Columbia Regional

CHSCOU

Charleston

Thu 8/27

6:30 am-10:16 am

1 stop4h 46m

Columbia Regional

Tue 9/1

10:55 am-11:59 pm

2 stops12h 04m

$351

CharlestonColumbia

CHS Charleston - COU Columbia Regional

CHSCOU

Charleston

Thu 8/27

2:54 pm-10:55 pm

2 stops9h 01m

Columbia Regional

Tue 9/1

10:55 am-11:59 pm

2 stops12h 04m

$356
Quickest round-trip

CharlotteColumbia

CLT Charlotte Douglas - COU Columbia Regional

CLTCOU

Charlotte Douglas

Tue 10/27

8:34 pm-9:53 pm

Nonstop2h 19m

Columbia Regional

Tue 11/3

8:12 am-11:25 am

Nonstop2h 13m

$383

ColumbiaColumbia

CAE Columbia Metropolitan - COU Columbia Regional

CAECOU

Columbia Metropolitan

Wed 9/9

5:38 pm-10:55 pm

1 stop6h 17m

Columbia Regional

Sat 9/12

3:11 pm-9:13 pm

1 stop5h 02m

$388

ColumbiaColumbia

CAE Columbia Metropolitan - COU Columbia Regional

CAECOU

Columbia Metropolitan

Wed 1/13

5:25 pm-9:33 pm

1 stop5h 08m

Columbia Regional

Sat 1/16

3:16 pm-9:16 pm

1 stop5h 00m

$388

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from South Carolina to Columbia, Missouri

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on South Carolina to Columbia, Missouri flights?

You could potentially save up to 24% on your flight if you consider stops on a South Carolina to Columbia, Missouri flight.

Cheap South Carolina to Columbia, Missouri flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Columbia, Missouri

Fastest flight time

2h 11m

Direct flights

Mon, Wed, Thu, Fri, Sat and Sun

Airports in Columbia, Missouri

1 airport
The fastest flight from South Carolina to Columbia, Missouri takes 2h 11m
Direct flights go from South Carolina to Columbia, Missouri on Monday, Wednesday, Thursday, Friday, Saturday and Sunday. There are no airlines offering direct flights.
There is 1 airport in Columbia, Missouri. From South Carolina there are direct flights to Columbia Regional (COU).
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Frequently asked questions about flying from South Carolina to Columbia, Missouri

  • When did momondo last update prices for flights from South Carolina to Columbia Regional Airport?

    Prices for flights from South Carolina to Columbia Regional Airport are updated daily.

  • How many operators does momondo search for flights from South Carolina to Columbia Regional Airport?

  • How old do you have to be to fly from South Carolina to Columbia Regional Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from South Carolina to Columbia Regional Airport.

  • What documentation or ID do you need to fly to Columbia Regional Airport?

    The travel and health documents you'll need for your trip to Columbia Regional Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Columbia Regional Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from South Carolina to Columbia, Missouri

Compare and see reviews for airlines that fly from South Carolina to Columbia, Missouri with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $253Free CancellationRating
7.4
10,111 reviews
Search United Airlines flights
American AirlinesPriceFrom $308Free CancellationRating
7.1
11,911 reviews
Search American Airlines flights

Traveling to a place near Columbia?

Book flights to Columbia if you plan to visit one of these locations
Jefferson City
Sedalia
Moberly
Lincoln

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Columbia?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from South Carolina to Columbia. momondo saves you time and could save you money on your trip.

Can I find flights from South Carolina to Columbia with flexible booking policies on momondo?

All flight searches from South Carolina to Columbia on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from South Carolina to Columbia?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Columbia from South Carolina.

I’m not ready to book a flight from South Carolina to Columbia right now. Can momondo alert me if prices change?

Price alerts on flights to Columbia from South Carolina are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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