Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Sioux Falls to Panama City from $259

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Sioux Falls to Panama City departing on 10/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Sioux Falls to Panama City

Cheap round-trip flights

American Airlines Logo
1:27 pm - 7:32 pmFSD-ECP
6h 05m1 stop
American Airlines Logo
6:31 am - 12:45 pmECP-FSD
6h 14m1 stop
$259American Airlines
Find Deal
sáb., oct. 25 - mar., oct. 28
Delta Logo
5:18 am - 12:47 pmFSD-ECP
7h 29m2 stops
Delta Logo
5:00 pm - 11:13 pmECP-FSD
6h 13m1 stop
$264Delta
Find Deal
sáb., dic. 6 - mar., dic. 9
American Airlines Logo
1:27 pm - 11:44 pmFSD-ECP
10h 17m2 stops
American Airlines Logo
6:49 am - 4:55 pmECP-FSD
10h 06m2 stops
$269American Airlines
Find Deal
sáb., oct. 25 - mar., oct. 28
United Airlines Logo
8:00 am - 1:10 pmFSD-ECP
5h 10m1 stop
United Airlines Logo
1:55 pm - 10:22 pmECP-FSD
8h 27m1 stop
$289United Airlines
Find Deal
mar., sep. 30 - sáb., oct. 4
Delta Logo
1:35 pm - 10:41 pmFSD-ECP
9h 06m2 stops
Delta Logo
5:00 pm - 10:56 pmECP-FSD
5h 56m1 stop
$304Delta
Find Deal
sáb., oct. 25 - mié., oct. 29
Delta Logo
5:18 am - 3:53 pmFSD-ECP
10h 35m2 stops
Delta Logo
1:45 pm - 12:48 pmECP-FSD
23h 03m2 stops
$318Delta
Find Deal
sáb., dic. 6 - mar., dic. 9
Delta Logo
5:30 am - 9:55 amFSD-ECP
4h 25m1 stop
Delta Logo
11:00 am - 10:44 pmECP-FSD
11h 44m2 stops
$324Delta
Find Deal
mar., sep. 30 - sáb., oct. 4
American Airlines Logo
6:04 pm - 12:54 pmFSD-ECP
18h 50m2 stops
American Airlines Logo
3:38 pm - 9:02 pmECP-FSD
5h 24m1 stop
$327American Airlines
Find Deal
lun., ene. 12 - sáb., ene. 17
United Airlines Logo
8:00 am - 4:16 pmFSD-ECP
8h 16m2 stops
United Airlines Logo
2:26 pm - 11:15 pmECP-FSD
8h 49m2 stops
$359United Airlines
Find Deal
mar., sep. 30 - sáb., oct. 4
United Airlines Logo
8:00 am - 9:48 pmFSD-ECP
13h 48m3 stops
United Airlines Logo
2:26 pm - 11:15 pmECP-FSD
8h 49m2 stops
$565United Airlines
Find Deal
mar., sep. 30 - sáb., oct. 4

Delta flights from Sioux Falls to Panama City, Florida

Our best Delta deals on Sioux Falls to Panama City, Florida flight tickets
Delta
Dec 6
FSD5:18 amSioux Falls Joe Foss Field
7h 29m
2 stops
ECP12:47 pmPanama City NW Florida Beaches
Dec 9
ECP5:00 pmPanama City NW Florida Beaches
6h 13m
1 stop
FSD11:13 pmSioux Falls Joe Foss Field
$264
Find similar
Delta
Oct 25
FSD1:35 pmSioux Falls Joe Foss Field
9h 06m
2 stops
ECP10:41 pmPanama City NW Florida Beaches
Oct 29
ECP5:00 pmPanama City NW Florida Beaches
5h 56m
1 stop
FSD10:56 pmSioux Falls Joe Foss Field
$304
Find similar
Delta
Dec 6
FSD5:18 amSioux Falls Joe Foss Field
10h 35m
2 stops
ECP3:53 pmPanama City NW Florida Beaches
Dec 9
ECP1:45 pmPanama City NW Florida Beaches
23h 03m
2 stops
FSD12:48 pmSioux Falls Joe Foss Field
$318
Find similar

American Airlines flights from Sioux Falls to Panama City, Florida

Our best American Airlines deals on Sioux Falls to Panama City, Florida flight tickets
American Airlines
Oct 25
FSD1:27 pmSioux Falls Joe Foss Field
6h 05m
1 stop
ECP7:32 pmPanama City NW Florida Beaches
Oct 28
ECP6:31 amPanama City NW Florida Beaches
6h 14m
1 stop
FSD12:45 pmSioux Falls Joe Foss Field
$259
Find similar
American Airlines
Oct 25
FSD1:27 pmSioux Falls Joe Foss Field
10h 17m
2 stops
ECP11:44 pmPanama City NW Florida Beaches
Oct 28
ECP6:49 amPanama City NW Florida Beaches
10h 06m
2 stops
FSD4:55 pmSioux Falls Joe Foss Field
$269
Find similar
American Airlines
Jan 12
FSD6:04 pmSioux Falls Joe Foss Field
18h 50m
2 stops
ECP12:54 pmPanama City NW Florida Beaches
Jan 17
ECP3:38 pmPanama City NW Florida Beaches
5h 24m
1 stop
FSD9:02 pmSioux Falls Joe Foss Field
$327
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Sioux Falls to Panama City, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated septiembre 17, 2025.
Use the filters below to find and compare flights from Sioux Falls to Panama City, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

sáb. 10/25

1:27 pm-7:32 pm

1 stop6h 05m

Panama City NW Florida Beaches

mar. 10/28

6:31 am-12:45 pm

1 stop6h 14m

$259

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

sáb. 12/6

5:18 am-12:47 pm

2 stops7h 29m

Panama City NW Florida Beaches

mar. 12/9

5:00 pm-11:13 pm

1 stop6h 13m

$264

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

sáb. 10/25

1:27 pm-11:44 pm

2 stops10h 17m

Panama City NW Florida Beaches

mar. 10/28

6:49 am-4:55 pm

2 stops10h 06m

$269

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

mar. 9/30

8:00 am-1:10 pm

1 stop5h 10m

Panama City NW Florida Beaches

sáb. 10/4

1:55 pm-10:22 pm

1 stop8h 27m

$289

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

sáb. 10/25

1:35 pm-10:41 pm

2 stops9h 06m

Panama City NW Florida Beaches

mié. 10/29

5:00 pm-10:56 pm

1 stop5h 56m

$304

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

sáb. 12/6

5:18 am-3:53 pm

2 stops10h 35m

Panama City NW Florida Beaches

mar. 12/9

1:45 pm-12:48 pm

2 stops23h 03m

$318

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

mar. 9/30

5:30 am-9:55 am

1 stop4h 25m

Panama City NW Florida Beaches

sáb. 10/4

11:00 am-10:44 pm

2 stops11h 44m

$324

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

lun. 1/12

6:04 pm-12:54 pm

2 stops18h 50m

Panama City NW Florida Beaches

sáb. 1/17

3:38 pm-9:02 pm

1 stop5h 24m

$327

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

mar. 9/30

8:00 am-4:16 pm

2 stops8h 16m

Panama City NW Florida Beaches

sáb. 10/4

2:26 pm-11:15 pm

2 stops8h 49m

$359

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

mar. 9/30

8:00 am-9:48 pm

3 stops13h 48m

Panama City NW Florida Beaches

sáb. 10/4

2:26 pm-11:15 pm

2 stops8h 49m

$565

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Panama City from

How to get the cheapest flight ticket from Sioux Falls to Panama City, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City, Florida?

The cheapest month to fly to Panama City, Florida from Sioux Falls is in January. Flight prices, which tend to average around $333, are often lower during this time because this is during the off-season. The month of July is another great option to travel to Panama City, Florida, with average flight prices from Sioux Falls averaging around $352.

What is the cheapest day to depart on your flight to Panama City, Florida?

Our data shows that Thursday is the least expensive day to fly to Panama City, Florida. Tickets to fly out on this day can be as low as $332. On the other hand, Wednesday is the most expensive day to depart from Sioux Falls because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $555.

When to book flights from Sioux Falls to Panama City, Florida

Are you open to changing your travel dates? Check out the ideal times to fly from Sioux Falls to Panama City, Florida according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Sioux Falls to Panama City, Florida (FSD to ECP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Sioux Falls to Panama City, Florida

Direct flights

None
There are no direct flights from Sioux Falls to Panama City, Florida. There are no popular flight routes from Sioux Falls to Panama City, Florida.
Search flight deals

  • How far is Sioux Falls Joe Foss Field to Panama City NW Florida Beaches by plane?

    The straight-line distance from Sioux Falls Joe Foss Field to Panama City NW Florida Beaches is 1106.0 mi. In terms of flight time, this usually takes a little over 4h 25m.

  • When did momondo last update prices for flights from Sioux Falls Joe Foss Field Airport to Panama City NW Florida Beaches Airport?

    Prices for flights from Sioux Falls Joe Foss Field Airport to Panama City NW Florida Beaches Airport are updated daily.

  • How many operators does momondo search for flights from Sioux Falls Joe Foss Field Airport to Panama City NW Florida Beaches Airport?

  • How old do you have to be to fly from Sioux Falls Joe Foss Field Airport to Panama City NW Florida Beaches Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Sioux Falls Joe Foss Field Airport to Panama City NW Florida Beaches Airport.

  • What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

    The required travel and health documents for your Panama City NW Florida Beaches Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City NW Florida Beaches Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Sioux Falls to Panama City, Florida?

Best airlines flying from Sioux Falls to Panama City, Florida

Compare and see reviews for airlines that fly from Sioux Falls to Panama City, Florida with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $254Free CancellationRating
7.4
8,926 reviews
Search United Airlines flights
DeltaPriceFrom $258Free CancellationRating
7.9
7,961 reviews
Search Delta flights
American AirlinesPriceFrom $258Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Panama City Beach
Rosemary Beach
Port St. Joe
Seaside
Mexico Beach
Seagrove Beach
Freeport

Why use momondo?

Why should I use momondo to find a flight deal from Sioux Falls to Panama City?

Finding the right flight to Panama City from Sioux Falls is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Panama City quick and easy, saving you time and money.

Can I find flights from Sioux Falls to Panama City with flexible booking policies on momondo?

momondo does allow users to show only those flights to Panama City from Sioux Falls which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Sioux Falls to Panama City?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Sioux Falls to Panama City.

I’m not ready to book a flight from Sioux Falls to Panama City right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Panama City, momondo offers a useful price alert feature which will track prices for flights to Panama City from Sioux Falls and alert you when they change.

An easier way to manage your Panama City, Florida trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
vie. 10/17
vie. 10/24
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States