Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Sioux Falls to Panama City from $284

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Sioux Falls to Panama City departing on 1/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Sioux Falls to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:00 am - 5:33 pm
FSD
-
ECP
11h 33m2 stops
American Airlines Logo
3:27 pm - 10:04 pm
ECP
-
FSD
6h 37m1 stop
$284American Airlines
Wed, Jan 21 - Thu, Jan 29
United Airlines Logo
6:00 am - 4:12 pm
FSD
-
ECP
10h 12m2 stops
United Airlines Logo
1:10 pm - 11:44 pm
ECP
-
FSD
10h 34m2 stops
$319United Airlines
Fri, Jan 9 - Mon, Jan 12
American Airlines Logo
1:23 pm - 9:19 pm
FSD
-
ECP
7h 56m1 stop
American Airlines Logo
7:02 am - 12:53 pm
ECP
-
FSD
5h 51m1 stop
$334American Airlines
Wed, Jan 21 - Thu, Jan 29
American Airlines Logo
12:14 pm - 11:49 pm
FSD
-
ECP
11h 35m2 stops
American Airlines Logo
2:53 pm - 10:12 pm
ECP
-
FSD
7h 19m2 stops
$344American Airlines
Wed, Apr 1 - Wed, Apr 8
American Airlines Logo
1:23 pm - 9:19 pm
FSD
-
ECP
7h 56m1 stop
American Airlines Logo
3:27 pm - 10:04 pm
ECP
-
FSD
6h 37m1 stop
$401American Airlines
Fri, Jan 9 - Mon, Jan 12
American Airlines Logo
6:00 am - 5:33 pm
FSD
-
ECP
11h 33m2 stops
American Airlines Logo
3:27 pm - 10:04 pm
ECP
-
FSD
6h 37m1 stop
$406American Airlines
Fri, Jan 9 - Mon, Jan 12
American Airlines Logo
7:52 pm - 12:30 pm
FSD
-
ECP
16h 38m1 stop
American Airlines Logo
1:06 pm - 11:49 am
ECP
-
FSD
22h 43m1 stop
$407American Airlines
Thu, Feb 26 - Mon, Mar 2
American Airlines Logo
6:00 am - 5:33 pm
FSD
-
ECP
11h 33m2 stops
American Airlines Logo
12:03 pm - 10:04 pm
ECP
-
FSD
10h 01m2 stops
$411American Airlines
Wed, Jan 21 - Thu, Jan 29
American Airlines Logo
7:52 pm - 12:45 pm
FSD
-
ECP
16h 53m2 stops
American Airlines Logo
1:06 pm - 11:49 am
ECP
-
FSD
22h 43m1 stop
$412American Airlines
Thu, Feb 26 - Mon, Mar 2
United Airlines Logo
7:30 am - 4:12 pm
FSD
-
ECP
8h 42m2 stops
United Airlines Logo
6:30 am - 4:37 pm
ECP
-
FSD
10h 07m2 stops
$429United Airlines
Wed, Jan 28 - Sat, Jan 31

United Airlines flights from Sioux Falls to Panama City, Florida

Our best United Airlines deals on Sioux Falls to Panama City, Florida flight tickets
United Airlines
Jan 9
FSD6:00 amSioux Falls Joe Foss Field
10h 12m
2 stops
ECP4:12 pmPanama City NW Florida Beaches
Jan 12
ECP1:10 pmPanama City NW Florida Beaches
10h 34m
2 stops
FSD11:44 pmSioux Falls Joe Foss Field
$319
Find similar
United Airlines
Jan 28
FSD7:30 amSioux Falls Joe Foss Field
8h 42m
2 stops
ECP4:12 pmPanama City NW Florida Beaches
Jan 31
ECP6:30 amPanama City NW Florida Beaches
10h 07m
2 stops
FSD4:37 pmSioux Falls Joe Foss Field
$426
Find similar
United Airlines
Jan 28
FSD7:30 amSioux Falls Joe Foss Field
8h 42m
2 stops
ECP4:12 pmPanama City NW Florida Beaches
Jan 31
ECP6:30 amPanama City NW Florida Beaches
10h 07m
2 stops
FSD4:37 pmSioux Falls Joe Foss Field
$429
Find similar

American Airlines flights from Sioux Falls to Panama City, Florida

Our best American Airlines deals on Sioux Falls to Panama City, Florida flight tickets
American Airlines
Jan 21
FSD6:00 amSioux Falls Joe Foss Field
11h 33m
2 stops
ECP5:33 pmPanama City NW Florida Beaches
Jan 29
ECP3:27 pmPanama City NW Florida Beaches
6h 37m
1 stop
FSD10:04 pmSioux Falls Joe Foss Field
$284
Find similar
American Airlines
Jan 21
FSD1:23 pmSioux Falls Joe Foss Field
7h 56m
1 stop
ECP9:19 pmPanama City NW Florida Beaches
Jan 29
ECP7:02 amPanama City NW Florida Beaches
5h 51m
1 stop
FSD12:53 pmSioux Falls Joe Foss Field
$334
Find similar
American Airlines
Feb 20
FSD1:23 pmSioux Falls Joe Foss Field
10h 29m
2 stops
ECP11:52 pmPanama City NW Florida Beaches
Feb 25
ECP10:20 amPanama City NW Florida Beaches
12h 14m
2 stops
FSD10:34 pmSioux Falls Joe Foss Field
$344
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Sioux Falls to Panama City, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Sioux Falls to Panama City, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

Wed 1/21

6:00 am-5:33 pm

2 stops11h 33m

Panama City NW Florida Beaches

Thu 1/29

3:27 pm-10:04 pm

1 stop6h 37m

$284

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

Fri 1/9

6:00 am-4:12 pm

2 stops10h 12m

Panama City NW Florida Beaches

Mon 1/12

1:10 pm-11:44 pm

2 stops10h 34m

$319

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

Wed 1/21

1:23 pm-9:19 pm

1 stop7h 56m

Panama City NW Florida Beaches

Thu 1/29

7:02 am-12:53 pm

1 stop5h 51m

$334

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

Wed 4/1

12:14 pm-11:49 pm

2 stops11h 35m

Panama City NW Florida Beaches

Wed 4/8

2:53 pm-10:12 pm

2 stops7h 19m

$344

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

Fri 1/9

1:23 pm-9:19 pm

1 stop7h 56m

Panama City NW Florida Beaches

Mon 1/12

3:27 pm-10:04 pm

1 stop6h 37m

$401

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

Fri 1/9

6:00 am-5:33 pm

2 stops11h 33m

Panama City NW Florida Beaches

Mon 1/12

3:27 pm-10:04 pm

1 stop6h 37m

$406

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

Thu 2/26

7:52 pm-12:30 pm

1 stop16h 38m

Panama City NW Florida Beaches

Mon 3/2

1:06 pm-11:49 am

1 stop22h 43m

$407

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

Wed 1/21

6:00 am-5:33 pm

2 stops11h 33m

Panama City NW Florida Beaches

Thu 1/29

12:03 pm-10:04 pm

2 stops10h 01m

$411

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

Thu 2/26

7:52 pm-12:45 pm

2 stops16h 53m

Panama City NW Florida Beaches

Mon 3/2

1:06 pm-11:49 am

1 stop22h 43m

$412

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

Wed 1/28

7:30 am-4:12 pm

2 stops8h 42m

Panama City NW Florida Beaches

Sat 1/31

6:30 am-4:37 pm

2 stops10h 07m

$429

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Panama City from

How to get the cheapest flight ticket from Sioux Falls to Panama City, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Sioux Falls and Panama City, Florida?

What is the cheapest month to fly to Panama City, Florida?

The cheapest month to fly to Panama City, Florida from Sioux Falls is in January. Flight prices, which tend to average around $306, are often lower during this time because this is during the off-season. The month of July is another great option to travel to Panama City, Florida, with average flight prices from Sioux Falls averaging around $352.

What is the cheapest day to depart on your flight to Panama City, Florida?

Our data shows that Thursday is the least expensive day to fly to Panama City, Florida. Tickets to fly out on this day can be as low as $332. On the other hand, Wednesday is the most expensive day to depart from Sioux Falls because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $555.

When to book flights from Sioux Falls to Panama City, Florida

Are you open to changing your travel dates? Check out the ideal times to fly from Sioux Falls to Panama City, Florida according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Sioux Falls to Panama City, Florida (FSD to ECP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Sioux Falls to Panama City, Florida

Fastest flight time

9h 38m

Direct flights

None
The fastest flight from Sioux Falls to Panama City, Florida takes 9h 38m
There are no direct flights from Sioux Falls to Panama City, Florida. There are no popular flight routes from Sioux Falls to Panama City, Florida.
Search flight deals

  • How far is Sioux Falls Joe Foss Field to Panama City NW Florida Beaches by plane?

    The straight-line distance from Sioux Falls Joe Foss Field to Panama City NW Florida Beaches is 1106.0 mi. In terms of flight time, this usually takes a little over 9h 38m.

  • When did momondo last update prices for flights from Sioux Falls Joe Foss Field Airport to Panama City NW Florida Beaches Airport?

    Prices for flights from Sioux Falls Joe Foss Field Airport to Panama City NW Florida Beaches Airport are updated daily.

  • How many operators does momondo search for flights from Sioux Falls Joe Foss Field Airport to Panama City NW Florida Beaches Airport?

  • How old do you have to be to fly from Sioux Falls Joe Foss Field Airport to Panama City NW Florida Beaches Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Sioux Falls Joe Foss Field Airport to Panama City NW Florida Beaches Airport.

  • What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

    The required travel and health documents for your Panama City NW Florida Beaches Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City NW Florida Beaches Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Sioux Falls to Panama City, Florida?

Best airlines flying from Sioux Falls to Panama City, Florida

Compare and see reviews for airlines that fly from Sioux Falls to Panama City, Florida with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $254Free CancellationRating
7.4
9,091 reviews
Search United Airlines flights
DeltaPriceFrom $264Free CancellationRating
7.9
8,005 reviews
Search Delta flights
American AirlinesPriceFrom $274Free CancellationRating
7.2
11,054 reviews
Search American Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Panama City Beach
Rosemary Beach
Port St. Joe
Seaside
Mexico Beach
Seagrove Beach
Freeport

Why use momondo?

Why should I use momondo to find a flight deal from Sioux Falls to Panama City?

Finding the right flight to Panama City from Sioux Falls is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Panama City quick and easy, saving you time and money.

Can I find flights from Sioux Falls to Panama City with flexible booking policies on momondo?

momondo does allow users to show only those flights to Panama City from Sioux Falls which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Sioux Falls to Panama City?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Sioux Falls to Panama City.

I’m not ready to book a flight from Sioux Falls to Panama City right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Panama City, momondo offers a useful price alert feature which will track prices for flights to Panama City from Sioux Falls and alert you when they change.

An easier way to manage your Panama City, Florida trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Sat 1/17
Sat 1/24
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States