What is the cheapest airline that flies from Sioux Falls Joe Foss Field to Knoxville McGhee Tyson?

Delta, United Airlines, and Allegiant Air are the most popular carriers operating from Sioux Falls Joe Foss Field to Knoxville McGhee Tyson

What airlines fly to Knoxville?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Knoxville from Sioux Falls according to our data. American Airlines is the first choice among our users, with 44% of people opting to fly with this airline when traveling to Knoxville. Keep in mind that there are 3 different airlines that fly to Knoxville on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Sioux Falls Joe Foss Field Airport to Knoxville McGhee Tyson Airport?

Prices for flights from Sioux Falls Joe Foss Field Airport to Knoxville McGhee Tyson Airport are refreshed on a daily basis.

How many operators does momondo search for flights from Sioux Falls Joe Foss Field Airport to Knoxville McGhee Tyson Airport?

The number of operators available for flights from Sioux Falls Joe Foss Field Airport to Knoxville McGhee Tyson Airport is 3 as of October 2026.

How old do you have to be to fly from Sioux Falls Joe Foss Field Airport to Knoxville McGhee Tyson Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Sioux Falls Joe Foss Field Airport to Knoxville McGhee Tyson Airport.

What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

The travel and health documents you'll need for your trip to Knoxville McGhee Tyson Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$284 Cheap Flights from Sioux Falls to Knoxville in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Sioux Falls to Knoxville

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12:07 pm - 6:20 pmFSD Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson

5h 13m1 stop Chicago O'Hare Intl

6:55 pm - 12:41 amTYS Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field

6h 46m1 stop Chicago O'Hare Intl

$369American Airlines

Tue, Oct 13 - Sat, Oct 17

12:04 pm - 9:27 pmFSD Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson

8h 23m1 stop Dallas/Fort Worth

5:30 am - 11:24 amTYS Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field

6h 54m1 stop Dallas/Fort Worth

$375American Airlines

Tue, Dec 29 - Tue, Jan 5

12:53 pm - 10:54 pmFSD Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson

9h 01m2 stops Dallas/Fort Worth Charlotte Douglas

6:55 pm - 12:41 amTYS Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field

6h 46m1 stop Chicago O'Hare Intl

$397American Airlines

Tue, Oct 13 - Sat, Oct 17

7:30 am - 1:20 pmFSD Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson

4h 50m1 stop Chicago O'Hare Intl

4:28 pm - 11:44 pmTYS Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field

8h 16m1 stop Denver Intl

$435United Airlines

Sat, Jan 9 - Wed, Jan 13

7:30 am - 1:20 pmFSD Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson

4h 50m1 stop Chicago O'Hare Intl

6:30 am - 10:44 amTYS Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field

5h 14m1 stop Chicago O'Hare Intl

$435United Airlines

Sat, Jan 9 - Wed, Jan 13

7:40 am - 1:20 pmFSD Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson

4h 40m1 stop Chicago O'Hare Intl

5:38 pm - 11:50 pmTYS Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field

7h 12m1 stop Chicago O'Hare Intl

$435United Airlines

Sat, Jan 9 - Wed, Jan 13

5:10 pm - 11:10 pmFSD Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson

5h 00m1 stop Minneapolis St Paul

7:55 am - 12:11 pmTYS Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field

5h 16m1 stop Minneapolis St Paul

$437Delta

Sun, Dec 20 - Tue, Jan 5

5:10 pm - 11:10 pmFSD Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson

5h 00m1 stop Minneapolis St Paul

7:55 am - 12:11 pmTYS Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field

5h 16m1 stop Minneapolis St Paul

$497Delta

Sun, Dec 20 - Tue, Jan 5

5:37 pm - 7:35 pmFSD Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson

24h 58m2 stops Fort Lauderdale Tampa

6:33 pm - 9:49 amTYS Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field

16h 16m1 stop Tampa St. Petersburg

$679Multiple Airlines

Fri, Dec 18 - Sun, Jan 3

5:37 pm - 7:41 pmFSD Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson

25h 04m1 stop Fort Lauderdale

6:33 pm - 9:49 amTYS Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field

16h 16m1 stop Tampa St. Petersburg

$700Allegiant Air

Fri, Dec 18 - Sun, Jan 3

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American Airlines flights from Sioux Falls to Knoxville

Our best American Airlines deals on Sioux Falls to Knoxville flight tickets

American Airlines

Oct 13

FSD12:07 pmSioux Falls Joe Foss Field

5h 13m

1 stop

TYS6:20 pmKnoxville McGhee Tyson

Oct 17

TYS6:55 pmKnoxville McGhee Tyson

6h 46m

1 stop

FSD12:41 amSioux Falls Joe Foss Field

$369

American Airlines

Dec 29

FSD12:04 pmSioux Falls Joe Foss Field

8h 23m

1 stop

TYS9:27 pmKnoxville McGhee Tyson

Jan 5

TYS5:30 amKnoxville McGhee Tyson

6h 54m

1 stop

FSD11:24 amSioux Falls Joe Foss Field

$375

American Airlines

Oct 13

FSD12:53 pmSioux Falls Joe Foss Field

9h 01m

2 stops

TYS10:54 pmKnoxville McGhee Tyson

Oct 17

TYS6:55 pmKnoxville McGhee Tyson

6h 46m

1 stop

FSD12:41 amSioux Falls Joe Foss Field

$397

United Airlines flights from Sioux Falls to Knoxville

Our best United Airlines deals on Sioux Falls to Knoxville flight tickets

United Airlines

Jan 9

FSD6:00 amSioux Falls Joe Foss Field

7h 36m

1 stop

TYS2:36 pmKnoxville McGhee Tyson

Jan 13

TYS4:25 pmKnoxville McGhee Tyson

7h 31m

1 stop

FSD10:56 pmSioux Falls Joe Foss Field

$435

United Airlines

Jan 9

FSD3:06 pmSioux Falls Joe Foss Field

4h 53m

1 stop

TYS8:59 pmKnoxville McGhee Tyson

Jan 13

TYS1:55 pmKnoxville McGhee Tyson

7h 51m

2 stops

FSD8:46 pmSioux Falls Joe Foss Field

$440

United Airlines

Jan 9

FSD10:00 amSioux Falls Joe Foss Field

11h 14m

2 stops

TYS10:14 pmKnoxville McGhee Tyson

Jan 13

TYS10:45 amKnoxville McGhee Tyson

11h 01m

2 stops

FSD8:46 pmSioux Falls Joe Foss Field

$445

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Sioux FallsKnoxville

FSD Sioux Falls Joe Foss Field - TYS Knoxville McGhee Tyson

FSDTYS

Sioux Falls Joe Foss Field

Tue 10/13

12:07 pm-6:20 pm

1 stop5h 13m

Knoxville McGhee Tyson

Sat 10/17

6:55 pm-12:41 am

1 stop6h 46m

$369

Sioux FallsKnoxville

FSD Sioux Falls Joe Foss Field - TYS Knoxville McGhee Tyson

FSDTYS

Sioux Falls Joe Foss Field

Tue 12/29

12:04 pm-9:27 pm

1 stop8h 23m

Knoxville McGhee Tyson

Tue 1/5

5:30 am-11:24 am

1 stop6h 54m

$375

Sioux FallsKnoxville

FSD Sioux Falls Joe Foss Field - TYS Knoxville McGhee Tyson

FSDTYS

Sioux Falls Joe Foss Field

Tue 10/13

12:53 pm-10:54 pm

2 stops9h 01m

Knoxville McGhee Tyson

Sat 10/17

6:55 pm-12:41 am

1 stop6h 46m

$397

Sioux FallsKnoxville

FSD Sioux Falls Joe Foss Field - TYS Knoxville McGhee Tyson

FSDTYS

Sioux Falls Joe Foss Field

Sat 1/9

7:30 am-1:20 pm

1 stop4h 50m

Knoxville McGhee Tyson

Wed 1/13

4:28 pm-11:44 pm

1 stop8h 16m

$435

Quickest round-trip

Sioux FallsKnoxville

FSD Sioux Falls Joe Foss Field - TYS Knoxville McGhee Tyson

FSDTYS

Sioux Falls Joe Foss Field

Sat 1/9

7:30 am-1:20 pm

1 stop4h 50m

Knoxville McGhee Tyson

Wed 1/13

6:30 am-10:44 am

1 stop5h 14m

$435

Sioux FallsKnoxville

FSD Sioux Falls Joe Foss Field - TYS Knoxville McGhee Tyson

FSDTYS

Sioux Falls Joe Foss Field

Sat 1/9

7:40 am-1:20 pm

1 stop4h 40m

Knoxville McGhee Tyson

Wed 1/13

5:38 pm-11:50 pm

1 stop7h 12m

$435

Sioux FallsKnoxville

FSD Sioux Falls Joe Foss Field - TYS Knoxville McGhee Tyson

FSDTYS

Sioux Falls Joe Foss Field

Sun 12/20

5:10 pm-11:10 pm

1 stop5h 00m

Knoxville McGhee Tyson

Tue 1/5

7:55 am-12:11 pm

1 stop5h 16m

$437

Sioux FallsKnoxville

FSD Sioux Falls Joe Foss Field - TYS Knoxville McGhee Tyson

FSDTYS

Sioux Falls Joe Foss Field

Sun 12/20

5:10 pm-11:10 pm

1 stop5h 00m

Knoxville McGhee Tyson

Tue 1/5

7:55 am-12:11 pm

1 stop5h 16m

$497

Sioux FallsKnoxville

FSD Sioux Falls Joe Foss Field - TYS Knoxville McGhee Tyson

FSDTYS

Sioux Falls Joe Foss Field

Fri 12/18

5:37 pm-7:35 pm

2 stops24h 58m

Knoxville McGhee Tyson

Sun 1/3

6:33 pm-9:49 am

1 stop16h 16m

$679

Sioux FallsKnoxville

FSD Sioux Falls Joe Foss Field - TYS Knoxville McGhee Tyson

FSDTYS

Sioux Falls Joe Foss Field

Fri 12/18

5:37 pm-7:41 pm

1 stop25h 04m

Knoxville McGhee Tyson

Sun 1/3

6:33 pm-9:49 am

1 stop16h 16m

$700

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first

How to get the cheapest flight ticket from Sioux Falls to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the typical price of a round-trip flight between Sioux Falls and Knoxville?

Prices are currently typical for flights on this route.

Typical prices usually range from $316 to $453.
The lowest price recently found on this route was $369.

What is the cheapest month to fly to Knoxville?

The month of March is, on average, the cheapest month to fly to Knoxville from Sioux Falls, with most prices found around $0. If you aren’t able to travel during the month of March, then book flights to Knoxville from Sioux Falls during April instead. Flights to Knoxville in April, while not as cheap as those in March, still average around $289.

Can stopping save me money on Sioux Falls to Knoxville flights?

You could potentially save up to 28% on your flight if you consider stops on a Sioux Falls to Knoxville flight.

When to book flights from Sioux Falls to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Sioux Falls to Knoxville according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Sioux Falls to Knoxville (FSD to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Sioux Falls to Knoxville

Best Price Found	$284
Fastest flight time	4h 41m
Direct flights	None

The best one-way flight to Knoxville from Sioux Falls in the past 72 hours is $284. The best round-trip flight deal from Sioux Falls to Knoxville found on momondo in the last 72 hours is $369.

The fastest flight from Sioux Falls to Knoxville takes 4h 41m

There are no direct flights from Sioux Falls to Knoxville. There are no popular flight routes from Sioux Falls to Knoxville.

Search flight deals

Frequently asked questions about flying from Sioux Falls to Knoxville

How far is Sioux Falls Joe Foss Field to Knoxville McGhee Tyson by plane?
The distance between Sioux Falls Joe Foss Field and Knoxville McGhee Tyson is about 856.6 mi. Flights usually cover this in 4h 41m, depending on flying conditions and air traffic around both airports.
When did momondo last update prices for flights from Sioux Falls Joe Foss Field Airport to Knoxville McGhee Tyson Airport?
Prices for flights from Sioux Falls Joe Foss Field Airport to Knoxville McGhee Tyson Airport are refreshed on a daily basis.
How many operators does momondo search for flights from Sioux Falls Joe Foss Field Airport to Knoxville McGhee Tyson Airport?
The number of operators available for flights from Sioux Falls Joe Foss Field Airport to Knoxville McGhee Tyson Airport is 3 as of October 2026.
How old do you have to be to fly from Sioux Falls Joe Foss Field Airport to Knoxville McGhee Tyson Airport?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Sioux Falls Joe Foss Field Airport to Knoxville McGhee Tyson Airport.
What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?
The travel and health documents you'll need for your trip to Knoxville McGhee Tyson Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from Sioux Falls to Knoxville?
momondo data reveals that the most frequently booked airline on the route from Sioux Falls to Knoxville is American Airlines, representing 45% of all bookings. The subsequent popular airlines are United Airlines at 29% and Delta at 27%.

Best airlines flying from Sioux Falls to Knoxville

Compare and see reviews for airlines that fly from Sioux Falls to Knoxville with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $268	Free Cancellation	Rating 7.0 12,129 reviews	Search American Airlines flights
Delta	PriceFrom $274	Free Cancellation	Rating 7.8 8,626 reviews	Search Delta flights
United Airlines	PriceFrom $304	Free Cancellation	Rating 7.4 10,283 reviews	Search United Airlines flights

Pigeon Forge

Gatlinburg

Cherokee

Bryson City

Morristown

Corbin

Alcoa

Crossville

Maryville

Murphy

Oak Ridge

Kodak

Newport

Lenoir City

Dandridge

Clinton

Rockford

Jefferson City

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Why should I use momondo to find a flight deal from Sioux Falls to Knoxville?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Sioux Falls to Knoxville. momondo saves you time and could save you money on your trip.

Can I find flights from Sioux Falls to Knoxville with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Sioux Falls to Knoxville flights to just show those with flexible booking policies.

How can momondo help me find flights from Sioux Falls to Knoxville?

momondo provides multiple filters to help you find the best flight to Knoxville from Sioux Falls. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Sioux Falls to Knoxville right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Knoxville, momondo offers a useful price alert feature which will track prices for flights to Knoxville from Sioux Falls and alert you when they change.

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Cheap flights from Sioux Falls to Knoxville from $284

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Sioux Falls to Knoxville departing on 10/31. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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American Airlines flights from Sioux Falls to Knoxville

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United Airlines flights from Sioux Falls to Knoxville

Our best United Airlines deals on Sioux Falls to Knoxville flight tickets

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How to get the cheapest flight ticket from Sioux Falls to Knoxville

What is the typical price of a round-trip flight between Sioux Falls and Knoxville?

What is the cheapest month to fly to Knoxville?

Can stopping save me money on Sioux Falls to Knoxville flights?

What is the cheapest airline that flies from Sioux Falls Joe Foss Field to Knoxville McGhee Tyson?

What airlines fly to Knoxville?

When to book flights from Sioux Falls to Knoxville

Cheap Sioux Falls to Knoxville (FSD to TYS) flight deals and tips

Best Price Found

Fastest flight time

Direct flights

Frequently asked questions about flying from Sioux Falls to Knoxville

Best airlines flying from Sioux Falls to Knoxville

Compare and see reviews for airlines that fly from Sioux Falls to Knoxville with momondo

Traveling to a place near Knoxville?

Why use momondo?

An easier way to manage your Knoxville trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing Tennessee

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List of cabin classes available on flights landing in Knoxville. Availability may vary depending on flight origin and airline.

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