Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Sioux Falls to Key West from $275

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Sioux Falls to Key West departing on 6/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Sioux Falls to Key West

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:00 am - 4:30 pm
FSD
-
EYW
9h 30m
2 stops
American Airlines Logo
2:29 pm - 9:54 pm
EYW
-
FSD
8h 25m
1 stop
$328American Airlines
Wed, May 6 - Tue, May 12
Multiple Airlines Logo
6:11 pm - 11:30 am
FSD
-
EYW
16h 19m
1 stop
Multiple Airlines Logo
4:22 pm - 5:21 pm
EYW
-
FSD
25h 59m
2 stops
$329Multiple Airlines
Mon, Apr 13 - Thu, Apr 16
Multiple Airlines Logo
6:11 pm - 11:30 am
FSD
-
EYW
16h 19m
1 stop
Multiple Airlines Logo
3:08 pm - 9:55 am
EYW
-
FSD
19h 47m
1 stop
$377Multiple Airlines
Mon, Apr 13 - Thu, Apr 16
Delta Logo
5:25 am - 1:09 pm
FSD
-
EYW
6h 44m
1 stop
Delta Logo
2:35 pm - 10:09 pm
EYW
-
FSD
8h 34m
1 stop
$378Delta
Sun, Sep 13 - Tue, Sep 22
American Airlines Logo
6:00 am - 4:30 pm
FSD
-
EYW
9h 30m
2 stops
American Airlines Logo
6:45 am - 4:58 pm
EYW
-
FSD
11h 13m
2 stops
$386American Airlines
Wed, May 6 - Tue, May 12
American Airlines Logo
1:41 pm - 10:58 pm
FSD
-
EYW
8h 17m
2 stops
American Airlines Logo
6:45 am - 2:47 pm
EYW
-
FSD
9h 02m
2 stops
$409American Airlines
Mon, May 11 - Sat, May 16
Delta Logo
5:25 am - 1:09 pm
FSD
-
EYW
6h 44m
1 stop
Delta Logo
2:35 pm - 10:09 pm
EYW
-
FSD
8h 34m
1 stop
$425Delta
Mon, Sep 14 - Tue, Sep 22
Delta Logo
1:20 pm - 1:09 pm
FSD
-
EYW
22h 49m
2 stops
Delta Logo
2:35 pm - 10:09 pm
EYW
-
FSD
8h 34m
1 stop
$455Delta
Mon, Sep 14 - Tue, Sep 22
American Airlines Logo
12:14 pm - 10:37 pm
FSD
-
EYW
9h 23m
2 stops
American Airlines Logo
2:25 pm - 9:40 pm
EYW
-
FSD
8h 15m
1 stop
$462American Airlines
Sat, Mar 28 - Wed, Apr 1
Delta Logo
5:15 am - 1:09 pm
FSD
-
EYW
6h 54m
2 stops
Delta Logo
2:35 pm - 10:09 pm
EYW
-
FSD
8h 34m
1 stop
$466Delta
Sun, Sep 13 - Tue, Sep 22

United Airlines flights from Sioux Falls to Key West

Our best United Airlines deals on Sioux Falls to Key West flight tickets
United Airlines
Apr 11
FSD6:10 amSioux Falls Joe Foss Field
7h 41m
1 stop
EYW2:51 pmKey West
Apr 15
EYW3:52 pmKey West
8h 52m
1 stop
FSD11:44 pmSioux Falls Joe Foss Field
$545
United Airlines
Apr 14
FSD6:10 amSioux Falls Joe Foss Field
10h 29m
2 stops
EYW5:39 pmKey West
Apr 18
EYW3:52 pmKey West
8h 52m
1 stop
FSD11:44 pmSioux Falls Joe Foss Field
$550
United Airlines
Apr 11
FSD6:10 amSioux Falls Joe Foss Field
7h 41m
1 stop
EYW2:51 pmKey West
Apr 17
EYW3:52 pmKey West
7h 02m
1 stop
FSD9:54 pmSioux Falls Joe Foss Field
$558

American Airlines flights from Sioux Falls to Key West

Our best American Airlines deals on Sioux Falls to Key West flight tickets
American Airlines
May 6
FSD6:00 amSioux Falls Joe Foss Field
9h 30m
2 stops
EYW4:30 pmKey West
May 12
EYW2:29 pmKey West
8h 25m
1 stop
FSD9:54 pmSioux Falls Joe Foss Field
$328
American Airlines
May 6
FSD6:00 amSioux Falls Joe Foss Field
9h 30m
2 stops
EYW4:30 pmKey West
May 12
EYW6:45 amKey West
11h 13m
2 stops
FSD4:58 pmSioux Falls Joe Foss Field
$386
American Airlines
May 11
FSD1:41 pmSioux Falls Joe Foss Field
8h 17m
2 stops
EYW10:58 pmKey West
May 16
EYW6:45 amKey West
9h 02m
2 stops
FSD2:47 pmSioux Falls Joe Foss Field
$409

momondo Fare Finder

 
Customize your flight search to find flights from Sioux Falls to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 18, 2026.
Use the filters below to find and compare flights from Sioux Falls to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Wed 5/6

6:00 am-4:30 pm

2 stops9h 30m

Key West

Tue 5/12

2:29 pm-9:54 pm

1 stop8h 25m

$328

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Mon 4/13

6:11 pm-11:30 am

1 stop16h 19m

Key West

Thu 4/16

4:22 pm-5:21 pm

2 stops25h 59m

$329

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Mon 4/13

6:11 pm-11:30 am

1 stop16h 19m

Key West

Thu 4/16

3:08 pm-9:55 am

1 stop19h 47m

$377
Quickest round-trip

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Sun 9/13

5:25 am-1:09 pm

1 stop6h 44m

Key West

Tue 9/22

2:35 pm-10:09 pm

1 stop8h 34m

$378

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Wed 5/6

6:00 am-4:30 pm

2 stops9h 30m

Key West

Tue 5/12

6:45 am-4:58 pm

2 stops11h 13m

$386

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Mon 5/11

1:41 pm-10:58 pm

2 stops8h 17m

Key West

Sat 5/16

6:45 am-2:47 pm

2 stops9h 02m

$409

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Mon 9/14

5:25 am-1:09 pm

1 stop6h 44m

Key West

Tue 9/22

2:35 pm-10:09 pm

1 stop8h 34m

$425

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Mon 9/14

1:20 pm-1:09 pm

2 stops22h 49m

Key West

Tue 9/22

2:35 pm-10:09 pm

1 stop8h 34m

$455

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Sat 3/28

12:14 pm-10:37 pm

2 stops9h 23m

Key West

Wed 4/1

2:25 pm-9:40 pm

1 stop8h 15m

$462

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Sun 9/13

5:15 am-1:09 pm

2 stops6h 54m

Key West

Tue 9/22

2:35 pm-10:09 pm

1 stop8h 34m

$466

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 15 resultsSorted by cheapest first
1
2

See travel insights to Key West from

How to get the cheapest flight ticket from Sioux Falls to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Sioux Falls to Key West flights?

You could potentially save up to 17% on your flight if you consider stops on a Sioux Falls to Key West flight.

When to book flights from Sioux Falls to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from Sioux Falls to Key West according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Sioux Falls to Key West (FSD to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Sioux Falls to Key West

Fastest flight time

6h 09m

Direct flights

None
The fastest flight from Sioux Falls to Key West takes 6h 09m
There are no direct flights from Sioux Falls to Key West. There are no popular flight routes from Sioux Falls to Key West.
Search flight deals

  • How far is Sioux Falls Joe Foss Field to Key West by plane?

    Sioux Falls Joe Foss Field and Key West are 1559.3 mi apart from one another. A reasonable flight in good conditions will take 6h 09m.

  • When did momondo last update prices for flights from Sioux Falls Joe Foss Field Airport to Key West Airport?

    Prices for flights from Sioux Falls Joe Foss Field Airport to Key West Airport are updated daily.

  • How many operators does momondo search for flights from Sioux Falls Joe Foss Field Airport to Key West Airport?

  • How old do you have to be to fly from Sioux Falls Joe Foss Field Airport to Key West Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Sioux Falls Joe Foss Field Airport to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The required travel and health documents for your Key West Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Key West Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Sioux Falls to Key West?

Best airlines flying from Sioux Falls to Key West

Compare and see reviews for airlines that fly from Sioux Falls to Key West with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $310Free CancellationRating
7.1
11,468 reviews
Search American Airlines flights
United AirlinesPriceFrom $490Free CancellationRating
7.4
9,435 reviews
Search United Airlines flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from Sioux Falls to Key West?

It is quick and easy to find Sioux Falls to Key West flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Key West that suits you.

Can I find flights from Sioux Falls to Key West with flexible booking policies on momondo?

Yes. All flights to Key West from Sioux Falls on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Sioux Falls to Key West?

Once you have performed a search for Sioux Falls to Key West flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Sioux Falls to Key West right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Key West, momondo offers a useful price alert feature which will track prices for flights to Key West from Sioux Falls and alert you when they change.

An easier way to manage your Key West trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Fri 4/17
Fri 4/24
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States