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Cheap flights from Sioux Falls to Key West from $288

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Sioux Falls to Key West departing on 5/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Sioux Falls to Key West

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:00 am - 4:30 pm
FSD
-
EYW
9h 30m
2 stops
American Airlines Logo
2:29 pm - 9:54 pm
EYW
-
FSD
8h 25m
1 stop
$288American Airlines
Tue, May 5 - Tue, May 12
American Airlines Logo
12:14 pm - 10:18 pm
FSD
-
EYW
9h 04m
2 stops
American Airlines Logo
6:45 am - 2:47 pm
EYW
-
FSD
9h 02m
2 stops
$293American Airlines
Tue, Mar 31 - Wed, Apr 8
United Airlines Logo
7:40 am - 3:00 pm
FSD
-
EYW
6h 20m
1 stop
United Airlines Logo
4:05 pm - 10:02 pm
EYW
-
FSD
6h 57m
1 stop
$296United Airlines
Tue, Mar 3 - Wed, Mar 11
American Airlines Logo
12:29 pm - 10:58 pm
FSD
-
EYW
9h 29m
2 stops
American Airlines Logo
2:29 pm - 9:54 pm
EYW
-
FSD
8h 25m
1 stop
$301American Airlines
Sat, Apr 25 - Thu, Apr 30
American Airlines Logo
6:00 am - 4:30 pm
FSD
-
EYW
9h 30m
2 stops
American Airlines Logo
2:29 pm - 9:54 pm
EYW
-
FSD
8h 25m
1 stop
$341American Airlines
Tue, May 5 - Tue, May 12
American Airlines Logo
12:14 pm - 10:22 pm
FSD
-
EYW
9h 08m
2 stops
American Airlines Logo
8:04 am - 7:10 pm
EYW
-
FSD
12h 06m
2 stops
$344American Airlines
Wed, Feb 25 - Wed, Mar 4
American Airlines Logo
5:44 am - 4:49 pm
FSD
-
EYW
10h 05m
2 stops
American Airlines Logo
2:25 pm - 9:40 pm
EYW
-
FSD
8h 15m
1 stop
$354American Airlines
Tue, Mar 3 - Wed, Mar 11
American Airlines Logo
5:44 am - 4:49 pm
FSD
-
EYW
10h 05m
2 stops
American Airlines Logo
7:45 am - 7:10 pm
EYW
-
FSD
12h 25m
2 stops
$359American Airlines
Tue, Mar 3 - Wed, Mar 11
United Airlines Logo
6:00 am - 2:51 pm
FSD
-
EYW
7h 51m
1 stop
United Airlines Logo
3:47 pm - 9:49 pm
EYW
-
FSD
7h 02m
1 stop
$365United Airlines
Tue, Mar 31 - Wed, Apr 8
American Airlines Logo
12:14 pm - 10:18 pm
FSD
-
EYW
9h 04m
2 stops
American Airlines Logo
2:25 pm - 9:40 pm
EYW
-
FSD
8h 15m
1 stop
$374American Airlines
Tue, Mar 24 - Wed, Apr 1

Allegiant Air flights from Sioux Falls to Key West

Our best Allegiant Air deals on Sioux Falls to Key West flight tickets
Allegiant Air
Jun 17
FSD1:06 pmSioux Falls Joe Foss Field
25h 06m
1 stop
EYW3:12 pmKey West
Jun 22
EYW3:25 pmKey West
21h 59m
1 stop
FSD12:24 pmSioux Falls Joe Foss Field
$396
Allegiant Air
May 20
FSD1:13 pmSioux Falls Joe Foss Field
25h 07m
1 stop
EYW3:20 pmKey West
May 25
EYW2:51 pmKey West
22h 40m
1 stop
FSD12:31 pmSioux Falls Joe Foss Field
$430
Allegiant Air
May 15
FSD10:45 amSioux Falls Joe Foss Field
23h 19m
1 stop
EYW11:04 amKey West
May 25
EYW2:51 pmKey West
22h 40m
1 stop
FSD12:31 pmSioux Falls Joe Foss Field
$459

American Airlines flights from Sioux Falls to Key West

Our best American Airlines deals on Sioux Falls to Key West flight tickets
American Airlines
May 5
FSD6:00 amSioux Falls Joe Foss Field
9h 30m
2 stops
EYW4:30 pmKey West
May 12
EYW2:29 pmKey West
8h 25m
1 stop
FSD9:54 pmSioux Falls Joe Foss Field
$288
American Airlines
Mar 31
FSD12:14 pmSioux Falls Joe Foss Field
9h 04m
2 stops
EYW10:18 pmKey West
Apr 8
EYW6:45 amKey West
9h 02m
2 stops
FSD2:47 pmSioux Falls Joe Foss Field
$293
American Airlines
Apr 25
FSD12:29 pmSioux Falls Joe Foss Field
9h 29m
2 stops
EYW10:58 pmKey West
Apr 30
EYW2:29 pmKey West
8h 25m
1 stop
FSD9:54 pmSioux Falls Joe Foss Field
$301

momondo Fare Finder

 
Customize your flight search to find flights from Sioux Falls to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 9, 2026.
Use the filters below to find and compare flights from Sioux Falls to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Tue 5/5

6:00 am-4:30 pm

2 stops9h 30m

Key West

Tue 5/12

2:29 pm-9:54 pm

1 stop8h 25m

$288

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Tue 3/31

12:14 pm-10:18 pm

2 stops9h 04m

Key West

Wed 4/8

6:45 am-2:47 pm

2 stops9h 02m

$293

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Tue 3/3

7:40 am-3:00 pm

1 stop6h 20m

Key West

Wed 3/11

4:05 pm-10:02 pm

1 stop6h 57m

$296

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Sat 4/25

12:29 pm-10:58 pm

2 stops9h 29m

Key West

Thu 4/30

2:29 pm-9:54 pm

1 stop8h 25m

$301

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Tue 5/5

6:00 am-4:30 pm

2 stops9h 30m

Key West

Tue 5/12

2:29 pm-9:54 pm

1 stop8h 25m

$341

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Wed 2/25

12:14 pm-10:22 pm

2 stops9h 08m

Key West

Wed 3/4

8:04 am-7:10 pm

2 stops12h 06m

$344

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Tue 3/3

5:44 am-4:49 pm

2 stops10h 05m

Key West

Wed 3/11

2:25 pm-9:40 pm

1 stop8h 15m

$354

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Tue 3/3

5:44 am-4:49 pm

2 stops10h 05m

Key West

Wed 3/11

7:45 am-7:10 pm

2 stops12h 25m

$359

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Tue 3/31

6:00 am-2:51 pm

1 stop7h 51m

Key West

Wed 4/8

3:47 pm-9:49 pm

1 stop7h 02m

$365

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Tue 3/24

12:14 pm-10:18 pm

2 stops9h 04m

Key West

Wed 4/1

2:25 pm-9:40 pm

1 stop8h 15m

$374

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Key West from

How to get the cheapest flight ticket from Sioux Falls to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Sioux Falls to Key West flights?

You could potentially save up to 25% on your flight if you consider stops on a Sioux Falls to Key West flight.

When to book flights from Sioux Falls to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from Sioux Falls to Key West according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Sioux Falls to Key West (FSD to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Sioux Falls to Key West

Fastest flight time

5h 54m

Direct flights

None
The fastest flight from Sioux Falls to Key West takes 5h 54m
There are no direct flights from Sioux Falls to Key West. There are no popular flight routes from Sioux Falls to Key West.
Search flight deals

  • How far is Sioux Falls Joe Foss Field to Key West by plane?

    Sioux Falls Joe Foss Field and Key West are 1559.3 mi apart from one another. A reasonable flight in good conditions will take 5h 54m.

  • When did momondo last update prices for flights from Sioux Falls Joe Foss Field Airport to Key West Airport?

    Prices for flights from Sioux Falls Joe Foss Field Airport to Key West Airport are updated daily.

  • How many operators does momondo search for flights from Sioux Falls Joe Foss Field Airport to Key West Airport?

  • How old do you have to be to fly from Sioux Falls Joe Foss Field Airport to Key West Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Sioux Falls Joe Foss Field Airport to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The required travel and health documents for your Key West Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Key West Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Sioux Falls to Key West?

Best airlines flying from Sioux Falls to Key West

Compare and see reviews for airlines that fly from Sioux Falls to Key West with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $288Free CancellationRating
7.2
11,258 reviews
Search American Airlines flights
United AirlinesPriceFrom $490Free CancellationRating
7.4
9,262 reviews
Search United Airlines flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from Sioux Falls to Key West?

It is quick and easy to find Sioux Falls to Key West flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Key West that suits you.

Can I find flights from Sioux Falls to Key West with flexible booking policies on momondo?

Yes. All flights to Key West from Sioux Falls on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Sioux Falls to Key West?

Once you have performed a search for Sioux Falls to Key West flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Sioux Falls to Key West right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Key West, momondo offers a useful price alert feature which will track prices for flights to Key West from Sioux Falls and alert you when they change.

An easier way to manage your Key West trip

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