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Cheap flights from Sioux Falls to Key West from $244

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Sioux Falls to Key West departing on 1/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:00 am - 7:10 pm
FSD
-
EYW
12h 10m2 stops
American Airlines Logo
1:06 pm - 9:35 pm
EYW
-
FSD
9h 29m1 stop
$244American Airlines
Tue, Jan 20 - Tue, Feb 3
American Airlines Logo
12:26 pm - 9:47 pm
FSD
-
EYW
8h 21m2 stops
American Airlines Logo
12:00 pm - 9:35 pm
EYW
-
FSD
10h 35m2 stops
$249American Airlines
Tue, Jan 20 - Tue, Feb 3
American Airlines Logo
6:00 am - 3:25 pm
FSD
-
EYW
8h 25m1 stop
American Airlines Logo
1:06 pm - 9:35 pm
EYW
-
FSD
9h 29m1 stop
$261American Airlines
Tue, Jan 20 - Tue, Feb 3
American Airlines Logo
12:19 pm - 10:49 pm
FSD
-
EYW
9h 30m2 stops
American Airlines Logo
2:40 pm - 9:39 pm
EYW
-
FSD
7h 59m1 stop
$266American Airlines
Wed, Feb 25 - Wed, Mar 4
American Airlines Logo
12:26 pm - 9:47 pm
FSD
-
EYW
8h 21m2 stops
American Airlines Logo
4:01 pm - 9:35 pm
EYW
-
FSD
6h 34m1 stop
$269American Airlines
Fri, Jan 9 - Tue, Jan 13
American Airlines Logo
12:19 pm - 10:23 pm
FSD
-
EYW
9h 04m2 stops
American Airlines Logo
2:40 pm - 9:39 pm
EYW
-
FSD
7h 59m1 stop
$288American Airlines
Wed, Feb 25 - Wed, Mar 4
Multiple Airlines Logo
7:26 pm - 12:11 pm
FSD
-
EYW
15h 45m1 stop
Multiple Airlines Logo
9:49 am - 6:36 pm
EYW
-
FSD
9h 47m1 stop
$289Multiple Airlines
Fri, Jan 23 - Mon, Jan 26
American Airlines Logo
12:26 pm - 9:47 pm
FSD
-
EYW
8h 21m2 stops
American Airlines Logo
1:22 pm - 9:35 pm
EYW
-
FSD
9h 13m2 stops
$296American Airlines
Fri, Jan 9 - Tue, Jan 13
American Airlines Logo
1:22 pm - 11:56 pm
FSD
-
EYW
9h 34m2 stops
American Airlines Logo
2:25 pm - 9:40 pm
EYW
-
FSD
8h 15m1 stop
$316American Airlines
Tue, Mar 24 - Wed, Apr 1
American Airlines Logo
7:00 am - 4:49 pm
FSD
-
EYW
8h 49m2 stops
American Airlines Logo
7:45 am - 4:49 pm
EYW
-
FSD
10h 04m2 stops
$321American Airlines
Tue, Mar 24 - Wed, Apr 1

United Airlines flights from Sioux Falls to Key West

Our best United Airlines deals on Sioux Falls to Key West flight tickets
United Airlines
Jan 21
FSD7:30 amSioux Falls Joe Foss Field
6h 47m
1 stop
EYW3:17 pmKey West
Jan 29
EYW4:15 pmKey West
6h 35m
1 stop
FSD9:50 pmSioux Falls Joe Foss Field
$389
Find similar
United Airlines
Apr 18
FSD5:50 amSioux Falls Joe Foss Field
9h 00m
2 stops
EYW3:50 pmKey West
Apr 23
EYW4:05 pmKey West
7h 09m
1 stop
FSD10:14 pmSioux Falls Joe Foss Field
$403
Find similar
United Airlines
Jan 22
FSD7:30 amSioux Falls Joe Foss Field
6h 47m
1 stop
EYW3:17 pmKey West
Jan 29
EYW4:15 pmKey West
6h 35m
1 stop
FSD9:50 pmSioux Falls Joe Foss Field
$429
Find similar

American Airlines flights from Sioux Falls to Key West

Our best American Airlines deals on Sioux Falls to Key West flight tickets
American Airlines
Jan 20
FSD6:00 amSioux Falls Joe Foss Field
12h 10m
2 stops
EYW7:10 pmKey West
Feb 3
EYW1:06 pmKey West
9h 29m
1 stop
FSD9:35 pmSioux Falls Joe Foss Field
$244
Find similar
American Airlines
Jan 20
FSD12:26 pmSioux Falls Joe Foss Field
8h 21m
2 stops
EYW9:47 pmKey West
Feb 3
EYW12:00 pmKey West
10h 35m
2 stops
FSD9:35 pmSioux Falls Joe Foss Field
$249
Find similar
American Airlines
Jan 20
FSD6:00 amSioux Falls Joe Foss Field
8h 25m
1 stop
EYW3:25 pmKey West
Feb 3
EYW1:06 pmKey West
9h 29m
1 stop
FSD9:35 pmSioux Falls Joe Foss Field
$261
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Sioux Falls to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 4, 2025.
Use the filters below to find and compare flights from Sioux Falls to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Tue 1/20

6:00 am-7:10 pm

2 stops12h 10m

Key West

Tue 2/3

1:06 pm-9:35 pm

1 stop9h 29m

$244

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Tue 1/20

12:26 pm-9:47 pm

2 stops8h 21m

Key West

Tue 2/3

12:00 pm-9:35 pm

2 stops10h 35m

$249

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Tue 1/20

6:00 am-3:25 pm

1 stop8h 25m

Key West

Tue 2/3

1:06 pm-9:35 pm

1 stop9h 29m

$261

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Wed 2/25

12:19 pm-10:49 pm

2 stops9h 30m

Key West

Wed 3/4

2:40 pm-9:39 pm

1 stop7h 59m

$266

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Fri 1/9

12:26 pm-9:47 pm

2 stops8h 21m

Key West

Tue 1/13

4:01 pm-9:35 pm

1 stop6h 34m

$269

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Wed 2/25

12:19 pm-10:23 pm

2 stops9h 04m

Key West

Wed 3/4

2:40 pm-9:39 pm

1 stop7h 59m

$288

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Fri 1/23

7:26 pm-12:11 pm

1 stop15h 45m

Key West

Mon 1/26

9:49 am-6:36 pm

1 stop9h 47m

$289

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Fri 1/9

12:26 pm-9:47 pm

2 stops8h 21m

Key West

Tue 1/13

1:22 pm-9:35 pm

2 stops9h 13m

$296

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Tue 3/24

1:22 pm-11:56 pm

2 stops9h 34m

Key West

Wed 4/1

2:25 pm-9:40 pm

1 stop8h 15m

$316

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Tue 3/24

7:00 am-4:49 pm

2 stops8h 49m

Key West

Wed 4/1

7:45 am-4:49 pm

2 stops10h 04m

$321

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Key West from

How to get the cheapest flight ticket from Sioux Falls to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Sioux Falls and Key West?

What is the cheapest month to fly to Key West?

In general, July is the cheapest month to fly from Sioux Falls to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $310. If you are unable to visit Key West during the month of July, then departing from Sioux Falls during the month September is also very affordable. Most momondo users find prices during this month for around $343.

What is the cheapest day to depart on your flight to Key West?

On average, the least expensive day to fly to Key West from Sioux Falls is on a Friday. momondo users have found tickets for Friday departures for as low as $302. However, this price may fluctuate depending on the airline, the season, and holidays. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Sioux Falls to Key West for around $660.

Can stopping save me money on Sioux Falls to Key West flights?

You could potentially save up to 47% on your flight if you consider stops on a Sioux Falls to Key West flight.

When to book flights from Sioux Falls to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from Sioux Falls to Key West according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Sioux Falls to Key West (FSD to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Sioux Falls to Key West

Fastest flight time

6h 44m

Direct flights

None
The fastest flight from Sioux Falls to Key West takes 6h 44m
There are no direct flights from Sioux Falls to Key West. There are no popular flight routes from Sioux Falls to Key West.
Search flight deals

  • How far is Sioux Falls Joe Foss Field to Key West by plane?

    Sioux Falls Joe Foss Field and Key West are 1559.3 mi apart from one another. A reasonable flight in good conditions will take 6h 47m.

  • When did momondo last update prices for flights from Sioux Falls Joe Foss Field Airport to Key West Airport?

    Prices for flights from Sioux Falls Joe Foss Field Airport to Key West Airport are updated daily.

  • How many operators does momondo search for flights from Sioux Falls Joe Foss Field Airport to Key West Airport?

  • How old do you have to be to fly from Sioux Falls Joe Foss Field Airport to Key West Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Sioux Falls Joe Foss Field Airport to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The required travel and health documents for your Key West Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Key West Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Sioux Falls to Key West?

Best airlines flying from Sioux Falls to Key West

Compare and see reviews for airlines that fly from Sioux Falls to Key West with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $310Free CancellationRating
7.2
11,047 reviews
Search American Airlines flights
DeltaPriceFrom $310Free CancellationRating
7.9
8,011 reviews
Search Delta flights
United AirlinesPriceFrom $353Free CancellationRating
7.4
9,066 reviews
Search United Airlines flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from Sioux Falls to Key West?

It is quick and easy to find Sioux Falls to Key West flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Key West that suits you.

Can I find flights from Sioux Falls to Key West with flexible booking policies on momondo?

Yes. All flights to Key West from Sioux Falls on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Sioux Falls to Key West?

Once you have performed a search for Sioux Falls to Key West flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Sioux Falls to Key West right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Key West, momondo offers a useful price alert feature which will track prices for flights to Key West from Sioux Falls and alert you when they change.

An easier way to manage your Key West trip

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