Cheap flights from Sioux Falls to Key West from $293

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Sioux Falls to Key West departing on 11/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

American Airlines Logo
10:59 am - 9:49 pmFSD-EYW
9h 50m2 stops
American Airlines Logo
1:23 pm - 10:27 pmEYW-FSD
10h 04m2 stops
$293American Airlines
Find Deal
Sat, Nov 8 - Wed, Nov 12
American Airlines Logo
12:37 pm - 11:59 pmFSD-EYW
10h 22m2 stops
American Airlines Logo
4:00 pm - 10:15 pmEYW-FSD
7h 15m1 stop
$321American Airlines
Find Deal
Wed, Feb 25 - Wed, Mar 4
American Airlines Logo
12:37 pm - 11:59 pmFSD-EYW
10h 22m2 stops
American Airlines Logo
6:31 am - 4:42 pmEYW-FSD
11h 11m2 stops
$326American Airlines
Find Deal
Wed, Feb 25 - Wed, Mar 4
American Airlines Logo
6:45 am - 4:04 pmFSD-EYW
8h 19m1 stop
American Airlines Logo
4:00 pm - 10:15 pmEYW-FSD
7h 15m1 stop
$349American Airlines
Find Deal
Wed, Feb 25 - Wed, Mar 4
United Airlines Logo
8:00 am - 3:19 pmFSD-EYW
6h 19m1 stop
United Airlines Logo
4:00 pm - 9:46 pmEYW-FSD
6h 46m1 stop
$373United Airlines
Find Deal
Tue, Oct 28 - Sat, Nov 1
Delta Logo
5:30 am - 1:02 pmFSD-EYW
6h 32m1 stop
Delta Logo
7:40 am - 7:19 pmEYW-FSD
12h 39m2 stops
$375Delta
Find Deal
Tue, Oct 28 - Sat, Nov 1
Delta Logo
5:30 am - 11:27 amFSD-EYW
4h 57m1 stop
Delta Logo
7:40 am - 3:44 pmEYW-FSD
9h 04m2 stops
$376Delta
Find Deal
Tue, Oct 28 - Sat, Nov 1
American Airlines Logo
10:59 am - 9:49 pmFSD-EYW
9h 50m2 stops
American Airlines Logo
2:01 pm - 10:27 pmEYW-FSD
9h 26m1 stop
$385American Airlines
Find Deal
Sat, Nov 8 - Wed, Nov 12
United Airlines Logo
8:50 am - 1:02 pmFSD-EYW
27h 12m2 stops
United Airlines Logo
1:30 pm - 9:50 pmEYW-FSD
33h 20m2 stops
$585United Airlines
Find Deal
Mon, Jan 5 - Fri, Jan 9
Allegiant Air Logo
10:35 am - 2:52 pmFSD-EYW
27h 17m2 stops
Allegiant Air Logo
3:30 pm - 10:03 amEYW-FSD
19h 33m1 stop
$696Allegiant Air
Find Deal
Mon, Nov 24 - Sun, Nov 30

United Airlines flights from Sioux Falls to Key West

Our best United Airlines deals on Sioux Falls to Key West flight tickets
United Airlines
Oct 28
FSD8:00 amSioux Falls Joe Foss Field
6h 19m
1 stop
EYW3:19 pmKey West
Nov 1
EYW4:00 pmKey West
6h 46m
1 stop
FSD9:46 pmSioux Falls Joe Foss Field
United Airlines
Jan 5
FSD8:50 amSioux Falls Joe Foss Field
27h 12m
2 stops
EYW1:02 pmKey West
Jan 9
EYW1:30 pmKey West
33h 20m
2 stops
FSD9:50 pmSioux Falls Joe Foss Field
United Airlines
Jan 5
FSD8:50 amSioux Falls Joe Foss Field
27h 12m
2 stops
EYW1:02 pmKey West
Jan 9
EYW4:15 pmKey West
19h 32m
1 stop
FSD10:47 amSioux Falls Joe Foss Field

American Airlines flights from Sioux Falls to Key West

Our best American Airlines deals on Sioux Falls to Key West flight tickets
American Airlines
Nov 8
FSD10:59 amSioux Falls Joe Foss Field
9h 50m
2 stops
EYW9:49 pmKey West
Nov 12
EYW1:23 pmKey West
10h 04m
2 stops
FSD10:27 pmSioux Falls Joe Foss Field
American Airlines
Feb 25
FSD12:37 pmSioux Falls Joe Foss Field
10h 22m
2 stops
EYW11:59 pmKey West
Mar 4
EYW4:00 pmKey West
7h 15m
1 stop
FSD10:15 pmSioux Falls Joe Foss Field
American Airlines
Feb 25
FSD12:37 pmSioux Falls Joe Foss Field
10h 22m
2 stops
EYW11:59 pmKey West
Mar 4
EYW6:31 amKey West
11h 11m
2 stops
FSD4:42 pmSioux Falls Joe Foss Field

momondo Fare Finder

 
Customize your flight search to find flights from Sioux Falls to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Sioux Falls to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Sat 11/8

10:59 am-9:49 pm

2 stops9h 50m

Key West

Wed 11/12

1:23 pm-10:27 pm

2 stops10h 04m

$293

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Wed 2/25

12:37 pm-11:59 pm

2 stops10h 22m

Key West

Wed 3/4

4:00 pm-10:15 pm

1 stop7h 15m

$321

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Wed 2/25

12:37 pm-11:59 pm

2 stops10h 22m

Key West

Wed 3/4

6:31 am-4:42 pm

2 stops11h 11m

$326

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Wed 2/25

6:45 am-4:04 pm

1 stop8h 19m

Key West

Wed 3/4

4:00 pm-10:15 pm

1 stop7h 15m

$349

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Tue 10/28

8:00 am-3:19 pm

1 stop6h 19m

Key West

Sat 11/1

4:00 pm-9:46 pm

1 stop6h 46m

$373

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Tue 10/28

5:30 am-1:02 pm

1 stop6h 32m

Key West

Sat 11/1

7:40 am-7:19 pm

2 stops12h 39m

$375

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Tue 10/28

5:30 am-11:27 am

1 stop4h 57m

Key West

Sat 11/1

7:40 am-3:44 pm

2 stops9h 04m

$376

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Sat 11/8

10:59 am-9:49 pm

2 stops9h 50m

Key West

Wed 11/12

2:01 pm-10:27 pm

1 stop9h 26m

$385

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Mon 1/5

8:50 am-1:02 pm

2 stops27h 12m

Key West

Fri 1/9

1:30 pm-9:50 pm

2 stops33h 20m

$585

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Mon 11/24

10:35 am-2:52 pm

2 stops27h 17m

Key West

Sun 11/30

3:30 pm-10:03 am

1 stop19h 33m

$696

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 15 resultsSorted by cheapest first
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See travel insights to Key West from

How to get the cheapest flight ticket from Sioux Falls to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Key West?

In general, July is the cheapest month to fly from Sioux Falls to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $310. If you are unable to visit Key West during the month of July, then departing from Sioux Falls during the month September is also very affordable. Most momondo users find prices during this month for around $343.

What is the cheapest day to depart on your flight to Key West?

On average, the least expensive day to fly to Key West from Sioux Falls is on a Friday. momondo users have found tickets for Friday departures for as low as $302. However, this price may fluctuate depending on the airline, the season, and holidays. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Sioux Falls to Key West for around $660.

Can stopping save me money on Sioux Falls to Key West flights?

You could potentially save up to 58% on your flight if you consider stops on a Sioux Falls to Key West flight.

When to book flights from Sioux Falls to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from Sioux Falls to Key West according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Sioux Falls to Key West (FSD to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Sioux Falls to Key West

Direct flights

None
There are no direct flights from Sioux Falls to Key West. There are no popular flight routes from Sioux Falls to Key West.
  • How far is Sioux Falls Joe Foss Field to Key West by plane?

    Sioux Falls Joe Foss Field and Key West are 1559.3 mi apart from one another. A reasonable flight in good conditions will take 4h 57m.

  • When did momondo last update prices for flights from Sioux Falls Joe Foss Field Airport to Key West Airport?

    Prices for flights from Sioux Falls Joe Foss Field Airport to Key West Airport are updated daily.

  • How many operators does momondo search for flights from Sioux Falls Joe Foss Field Airport to Key West Airport?

  • How old do you have to be to fly from Sioux Falls Joe Foss Field Airport to Key West Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Sioux Falls Joe Foss Field Airport to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The required travel and health documents for your Key West Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Key West Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Sioux Falls to Key West?

Best airlines flying from Sioux Falls to Key West

Compare and see reviews for airlines that fly from Sioux Falls to Key West with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $310Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
DeltaPriceFrom $310Free CancellationRating
7.9
7,961 reviews
Search Delta flights
United AirlinesPriceFrom $378Free CancellationRating
7.4
8,926 reviews
Search United Airlines flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from Sioux Falls to Key West?

It is quick and easy to find Sioux Falls to Key West flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Key West that suits you.

Can I find flights from Sioux Falls to Key West with flexible booking policies on momondo?

Yes. All flights to Key West from Sioux Falls on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Sioux Falls to Key West?

Once you have performed a search for Sioux Falls to Key West flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Sioux Falls to Key West right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Key West, momondo offers a useful price alert feature which will track prices for flights to Key West from Sioux Falls and alert you when they change.

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1 adult
Fri 10/17
Fri 10/24

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