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Cheap flights from Sioux Falls to Key West from $333

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Sioux Falls to Key West departing on 9/16. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Sioux Falls to Key West

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:00 am - 7:17 pm
FSD
-
EYW
12h 17m
2 stops
American Airlines Logo
1:47 pm - 12:29 am
EYW
-
FSD
11h 42m
2 stops
$333American Airlines
Wed, Sep 16 - Tue, Sep 22
American Airlines Logo
6:24 am - 4:18 pm
FSD
-
EYW
8h 54m
1 stop
American Airlines Logo
4:56 pm - 12:30 am
EYW
-
FSD
8h 34m
1 stop
$336American Airlines
Fri, Aug 28 - Wed, Sep 2
American Airlines Logo
6:24 am - 4:18 pm
FSD
-
EYW
8h 54m
1 stop
American Airlines Logo
1:49 pm - 12:30 am
EYW
-
FSD
11h 41m
2 stops
$341American Airlines
Fri, Aug 28 - Wed, Sep 2
American Airlines Logo
6:00 am - 7:17 pm
FSD
-
EYW
12h 17m
2 stops
American Airlines Logo
1:47 pm - 12:29 am
EYW
-
FSD
11h 42m
2 stops
$346American Airlines
Wed, Sep 16 - Tue, Sep 22
Delta Logo
6:15 am - 2:52 pm
FSD
-
EYW
7h 37m
2 stops
Delta Logo
2:00 pm - 7:49 pm
EYW
-
FSD
6h 49m
1 stop
$389Delta
Sat, Sep 5 - Thu, Sep 10
American Airlines Logo
6:00 am - 7:17 pm
FSD
-
EYW
12h 17m
2 stops
American Airlines Logo
2:15 pm - 12:29 am
EYW
-
FSD
11h 14m
2 stops
$399American Airlines
Fri, Sep 11 - Tue, Sep 15
Delta Logo
5:30 am - 12:21 pm
FSD
-
EYW
5h 51m
1 stop
Delta Logo
2:00 pm - 7:49 pm
EYW
-
FSD
6h 49m
1 stop
$401Delta
Sat, Sep 12 - Sat, Sep 19
Delta Logo
5:30 am - 2:52 pm
FSD
-
EYW
8h 22m
1 stop
Delta Logo
2:00 pm - 7:49 pm
EYW
-
FSD
6h 49m
1 stop
$414Delta
Sat, Sep 5 - Thu, Sep 10
American Airlines Logo
7:00 am - 5:55 pm
FSD
-
EYW
9h 55m
2 stops
American Airlines Logo
1:47 pm - 12:29 am
EYW
-
FSD
11h 42m
2 stops
$419American Airlines
Sat, Sep 26 - Tue, Sep 29
American Airlines Logo
7:30 am - 6:40 pm
FSD
-
EYW
10h 10m
2 stops
American Airlines Logo
1:47 pm - 12:29 am
EYW
-
FSD
11h 42m
2 stops
$432American Airlines
Sat, Sep 5 - Thu, Sep 10

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Delta flights from Sioux Falls to Key West

Our best Delta deals on Sioux Falls to Key West flight tickets
Delta
Sep 5
FSD6:15 amSioux Falls Joe Foss Field
7h 37m
2 stops
EYW2:52 pmKey West
Sep 10
EYW2:00 pmKey West
6h 49m
1 stop
FSD7:49 pmSioux Falls Joe Foss Field
$389
Delta
Sep 12
FSD5:30 amSioux Falls Joe Foss Field
5h 51m
1 stop
EYW12:21 pmKey West
Sep 19
EYW2:00 pmKey West
6h 49m
1 stop
FSD7:49 pmSioux Falls Joe Foss Field
$401
Delta
Sep 5
FSD5:30 amSioux Falls Joe Foss Field
8h 22m
1 stop
EYW2:52 pmKey West
Sep 10
EYW2:00 pmKey West
6h 49m
1 stop
FSD7:49 pmSioux Falls Joe Foss Field
$414

American Airlines flights from Sioux Falls to Key West

Our best American Airlines deals on Sioux Falls to Key West flight tickets
American Airlines
Sep 16
FSD6:00 amSioux Falls Joe Foss Field
12h 17m
2 stops
EYW7:17 pmKey West
Sep 22
EYW1:47 pmKey West
11h 42m
2 stops
FSD12:29 amSioux Falls Joe Foss Field
$333
American Airlines
Aug 28
FSD6:24 amSioux Falls Joe Foss Field
8h 54m
1 stop
EYW4:18 pmKey West
Sep 2
EYW4:56 pmKey West
8h 34m
1 stop
FSD12:30 amSioux Falls Joe Foss Field
$336
American Airlines
Aug 28
FSD6:24 amSioux Falls Joe Foss Field
8h 54m
1 stop
EYW4:18 pmKey West
Sep 2
EYW1:49 pmKey West
11h 41m
2 stops
FSD12:30 amSioux Falls Joe Foss Field
$341

momondo Fare Finder

 
Customize your flight search to find flights from Sioux Falls to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 16, 2026.
Use the filters below to find and compare flights from Sioux Falls to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Wed 9/16

6:00 am-7:17 pm

2 stops12h 17m

Key West

Tue 9/22

1:47 pm-12:29 am

2 stops11h 42m

$333

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Fri 8/28

6:24 am-4:18 pm

1 stop8h 54m

Key West

Wed 9/2

4:56 pm-12:30 am

1 stop8h 34m

$336

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Fri 8/28

6:24 am-4:18 pm

1 stop8h 54m

Key West

Wed 9/2

1:49 pm-12:30 am

2 stops11h 41m

$341

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Wed 9/16

6:00 am-7:17 pm

2 stops12h 17m

Key West

Tue 9/22

1:47 pm-12:29 am

2 stops11h 42m

$346

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Sat 9/5

6:15 am-2:52 pm

2 stops7h 37m

Key West

Thu 9/10

2:00 pm-7:49 pm

1 stop6h 49m

$389

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Fri 9/11

6:00 am-7:17 pm

2 stops12h 17m

Key West

Tue 9/15

2:15 pm-12:29 am

2 stops11h 14m

$399
Quickest round-trip

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Sat 9/12

5:30 am-12:21 pm

1 stop5h 51m

Key West

Sat 9/19

2:00 pm-7:49 pm

1 stop6h 49m

$401

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Sat 9/5

5:30 am-2:52 pm

1 stop8h 22m

Key West

Thu 9/10

2:00 pm-7:49 pm

1 stop6h 49m

$414

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Sat 9/26

7:00 am-5:55 pm

2 stops9h 55m

Key West

Tue 9/29

1:47 pm-12:29 am

2 stops11h 42m

$419

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Sat 9/5

7:30 am-6:40 pm

2 stops10h 10m

Key West

Thu 9/10

1:47 pm-12:29 am

2 stops11h 42m

$432

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Key West from

How to get the cheapest flight ticket from Sioux Falls to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Key West?

In general, April is the cheapest month to fly from Sioux Falls to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $408. If you are unable to visit Key West during the month of April, then departing from Sioux Falls during the month October is also very affordable. Most momondo users find prices during this month for around $425.

Can stopping save me money on Sioux Falls to Key West flights?

You could potentially save up to 17% on your flight if you consider stops on a Sioux Falls to Key West flight.

When to book flights from Sioux Falls to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from Sioux Falls to Key West according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Sioux Falls to Key West (FSD to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Sioux Falls to Key West

Fastest flight time

5h 28m

Direct flights

None
The fastest flight from Sioux Falls to Key West takes 5h 28m
There are no direct flights from Sioux Falls to Key West. There are no popular flight routes from Sioux Falls to Key West.
Search flight deals

Frequently asked questions about flying from Sioux Falls to Key West

  • How far is Sioux Falls Joe Foss Field to Key West by plane?

    Sioux Falls Joe Foss Field and Key West are 1559.3 mi apart from one another. A reasonable flight in good conditions will take 5h 28m.

  • When did momondo last update prices for flights from Sioux Falls Joe Foss Field Airport to Key West Airport?

    Prices for flights from Sioux Falls Joe Foss Field Airport to Key West Airport are updated daily.

  • How many operators does momondo search for flights from Sioux Falls Joe Foss Field Airport to Key West Airport?

  • How old do you have to be to fly from Sioux Falls Joe Foss Field Airport to Key West Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Sioux Falls Joe Foss Field Airport to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The required travel and health documents for your Key West Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Key West Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Sioux Falls to Key West?

Best airlines flying from Sioux Falls to Key West

Compare and see reviews for airlines that fly from Sioux Falls to Key West with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $310Free CancellationRating
7.1
11,814 reviews
Search American Airlines flights
DeltaPriceFrom $372Free CancellationRating
7.8
8,471 reviews
Search Delta flights
United AirlinesPriceFrom $456Free CancellationRating
7.4
9,993 reviews
Search United Airlines flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from Sioux Falls to Key West?

It is quick and easy to find Sioux Falls to Key West flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Key West that suits you.

Can I find flights from Sioux Falls to Key West with flexible booking policies on momondo?

Yes. All flights to Key West from Sioux Falls on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Sioux Falls to Key West?

Once you have performed a search for Sioux Falls to Key West flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Sioux Falls to Key West right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Key West, momondo offers a useful price alert feature which will track prices for flights to Key West from Sioux Falls and alert you when they change.

An easier way to manage your Key West trip

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