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Cheap flights from Sioux Falls to Key West from $278

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Sioux Falls to Key West departing on 1/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Sioux Falls to Key West

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:00 am - 3:25 pm
FSD
-
EYW
8h 25m1 stop
American Airlines Logo
6:06 am - 4:59 pm
EYW
-
FSD
11h 53m2 stops
$278American Airlines
Mon, Jan 12 - Sat, Jan 17
American Airlines Logo
12:26 pm - 9:47 pm
FSD
-
EYW
8h 21m2 stops
American Airlines Logo
6:06 am - 4:59 pm
EYW
-
FSD
11h 53m2 stops
$283American Airlines
Mon, Jan 12 - Sat, Jan 17
American Airlines Logo
1:23 pm - 10:54 pm
FSD
-
EYW
8h 31m2 stops
American Airlines Logo
2:40 pm - 9:39 pm
EYW
-
FSD
7h 59m1 stop
$288American Airlines
Wed, Feb 25 - Wed, Mar 4
United Airlines Logo
7:30 am - 3:17 pm
FSD
-
EYW
6h 47m1 stop
United Airlines Logo
4:15 pm - 9:50 pm
EYW
-
FSD
6h 35m1 stop
$290United Airlines
Mon, Jan 12 - Sat, Jan 17
American Airlines Logo
1:23 pm - 10:54 pm
FSD
-
EYW
8h 31m2 stops
American Airlines Logo
6:45 am - 4:47 pm
EYW
-
FSD
11h 02m2 stops
$293American Airlines
Wed, Feb 25 - Wed, Mar 4
American Airlines Logo
12:26 pm - 9:47 pm
FSD
-
EYW
8h 21m2 stops
American Airlines Logo
4:01 pm - 9:35 pm
EYW
-
FSD
6h 34m1 stop
$314American Airlines
Fri, Jan 30 - Fri, Feb 6
American Airlines Logo
12:26 pm - 9:47 pm
FSD
-
EYW
8h 21m2 stops
American Airlines Logo
12:00 pm - 9:35 pm
EYW
-
FSD
10h 35m2 stops
$319American Airlines
Fri, Jan 30 - Fri, Feb 6
Multiple Airlines Logo
6:11 pm - 11:17 am
FSD
-
EYW
16h 06m1 stop
Multiple Airlines Logo
3:08 pm - 9:55 am
EYW
-
FSD
19h 47m1 stop
$329Multiple Airlines
Mon, May 4 - Thu, May 14
American Airlines Logo
6:00 am - 4:19 pm
FSD
-
EYW
9h 19m1 stop
American Airlines Logo
2:40 pm - 9:39 pm
EYW
-
FSD
7h 59m1 stop
$336American Airlines
Wed, Feb 25 - Wed, Mar 4
Multiple Airlines Logo
6:02 pm - 12:26 pm
FSD
-
EYW
17h 24m1 stop
Multiple Airlines Logo
10:27 pm - 6:36 pm
EYW
-
FSD
21h 09m1 stop
$338Multiple Airlines
Sun, Feb 1 - Thu, Feb 5

Delta flights from Sioux Falls to Key West

Our best Delta deals on Sioux Falls to Key West flight tickets
Delta
May 3
FSD5:25 amSioux Falls Joe Foss Field
6h 45m
1 stop
EYW1:10 pmKey West
May 12
EYW2:35 pmKey West
8h 36m
1 stop
FSD10:11 pmSioux Falls Joe Foss Field
$359
Find similar
Delta
May 3
FSD5:25 amSioux Falls Joe Foss Field
6h 45m
1 stop
EYW1:10 pmKey West
May 13
EYW2:35 pmKey West
8h 36m
1 stop
FSD10:11 pmSioux Falls Joe Foss Field
$376
Find similar
Delta
May 6
FSD5:25 amSioux Falls Joe Foss Field
6h 45m
1 stop
EYW1:10 pmKey West
May 13
EYW2:35 pmKey West
8h 36m
1 stop
FSD10:11 pmSioux Falls Joe Foss Field
$393
Find similar

United Airlines flights from Sioux Falls to Key West

Our best United Airlines deals on Sioux Falls to Key West flight tickets
United Airlines
Jan 12
FSD7:30 amSioux Falls Joe Foss Field
6h 47m
1 stop
EYW3:17 pmKey West
Jan 17
EYW4:15 pmKey West
6h 35m
1 stop
FSD9:50 pmSioux Falls Joe Foss Field
$290
Find similar
United Airlines
May 5
FSD7:32 amSioux Falls Joe Foss Field
6h 27m
1 stop
EYW2:59 pmKey West
May 13
EYW3:52 pmKey West
7h 23m
1 stop
FSD10:15 pmSioux Falls Joe Foss Field
$373
Find similar
United Airlines
May 4
FSD7:32 amSioux Falls Joe Foss Field
6h 27m
1 stop
EYW2:59 pmKey West
May 13
EYW3:52 pmKey West
7h 23m
1 stop
FSD10:15 pmSioux Falls Joe Foss Field
$386
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Sioux Falls to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Sioux Falls to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Mon 1/12

6:00 am-3:25 pm

1 stop8h 25m

Key West

Sat 1/17

6:06 am-4:59 pm

2 stops11h 53m

$278

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Mon 1/12

12:26 pm-9:47 pm

2 stops8h 21m

Key West

Sat 1/17

6:06 am-4:59 pm

2 stops11h 53m

$283

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Wed 2/25

1:23 pm-10:54 pm

2 stops8h 31m

Key West

Wed 3/4

2:40 pm-9:39 pm

1 stop7h 59m

$288

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Mon 1/12

7:30 am-3:17 pm

1 stop6h 47m

Key West

Sat 1/17

4:15 pm-9:50 pm

1 stop6h 35m

$290

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Wed 2/25

1:23 pm-10:54 pm

2 stops8h 31m

Key West

Wed 3/4

6:45 am-4:47 pm

2 stops11h 02m

$293

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Fri 1/30

12:26 pm-9:47 pm

2 stops8h 21m

Key West

Fri 2/6

4:01 pm-9:35 pm

1 stop6h 34m

$314

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Fri 1/30

12:26 pm-9:47 pm

2 stops8h 21m

Key West

Fri 2/6

12:00 pm-9:35 pm

2 stops10h 35m

$319

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Mon 5/4

6:11 pm-11:17 am

1 stop16h 06m

Key West

Thu 5/14

3:08 pm-9:55 am

1 stop19h 47m

$329

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Wed 2/25

6:00 am-4:19 pm

1 stop9h 19m

Key West

Wed 3/4

2:40 pm-9:39 pm

1 stop7h 59m

$336

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Sun 2/1

6:02 pm-12:26 pm

1 stop17h 24m

Key West

Thu 2/5

10:27 pm-6:36 pm

1 stop21h 09m

$338

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 15 resultsSorted by cheapest first
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See travel insights to Key West from

How to get the cheapest flight ticket from Sioux Falls to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Sioux Falls and Key West?

What is the cheapest month to fly to Key West?

In general, July is the cheapest month to fly from Sioux Falls to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $310. If you are unable to visit Key West during the month of July, then departing from Sioux Falls during the month September is also very affordable. Most momondo users find prices during this month for around $343.

What is the cheapest day to depart on your flight to Key West?

On average, the least expensive day to fly to Key West from Sioux Falls is on a Friday. momondo users have found tickets for Friday departures for as low as $302. However, this price may fluctuate depending on the airline, the season, and holidays. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Sioux Falls to Key West for around $660.

Can stopping save me money on Sioux Falls to Key West flights?

You could potentially save up to 47% on your flight if you consider stops on a Sioux Falls to Key West flight.

When to book flights from Sioux Falls to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from Sioux Falls to Key West according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Sioux Falls to Key West (FSD to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Sioux Falls to Key West

Fastest flight time

6h 21m

Direct flights

None
The fastest flight from Sioux Falls to Key West takes 6h 21m
There are no direct flights from Sioux Falls to Key West. There are no popular flight routes from Sioux Falls to Key West.
Search flight deals

  • How far is Sioux Falls Joe Foss Field to Key West by plane?

    Sioux Falls Joe Foss Field and Key West are 1559.3 mi apart from one another. A reasonable flight in good conditions will take 6h 21m.

  • When did momondo last update prices for flights from Sioux Falls Joe Foss Field Airport to Key West Airport?

    Prices for flights from Sioux Falls Joe Foss Field Airport to Key West Airport are updated daily.

  • How many operators does momondo search for flights from Sioux Falls Joe Foss Field Airport to Key West Airport?

  • How old do you have to be to fly from Sioux Falls Joe Foss Field Airport to Key West Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Sioux Falls Joe Foss Field Airport to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The required travel and health documents for your Key West Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Key West Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Sioux Falls to Key West?

Best airlines flying from Sioux Falls to Key West

Compare and see reviews for airlines that fly from Sioux Falls to Key West with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $310Free CancellationRating
7.2
11,054 reviews
Search American Airlines flights
DeltaPriceFrom $310Free CancellationRating
7.9
8,005 reviews
Search Delta flights
United AirlinesPriceFrom $381Free CancellationRating
7.4
9,091 reviews
Search United Airlines flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from Sioux Falls to Key West?

It is quick and easy to find Sioux Falls to Key West flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Key West that suits you.

Can I find flights from Sioux Falls to Key West with flexible booking policies on momondo?

Yes. All flights to Key West from Sioux Falls on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Sioux Falls to Key West?

Once you have performed a search for Sioux Falls to Key West flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Sioux Falls to Key West right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Key West, momondo offers a useful price alert feature which will track prices for flights to Key West from Sioux Falls and alert you when they change.

An easier way to manage your Key West trip

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