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Cheap flights from Santo Domingo to Indianapolis from $345

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Santo Domingo to Indianapolis departing on 11/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

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Spirit Airlines Logo
4:35 pm - 11:19 pmSDQ-IND
7h 44m1 stop
Spirit Airlines Logo
7:00 am - 3:30 pmIND-SDQ
7h 30m1 stop
$345Spirit Airlines
Find Deal
Thu, Nov 20 - Tue, Dec 2
Spirit Airlines Logo
4:35 pm - 11:19 pmSDQ-IND
7h 44m1 stop
Spirit Airlines Logo
6:07 pm - 3:30 pmIND-SDQ
20h 23m2 stops
$355Spirit Airlines
Find Deal
Thu, Nov 20 - Tue, Dec 2
Multiple Airlines Logo
4:35 pm - 11:19 pmSDQ-IND
7h 44m1 stop
Multiple Airlines Logo
4:10 pm - 11:51 amIND-SDQ
18h 41m2 stops
$377Multiple Airlines
Find Deal
Mon, Nov 24 - Fri, Dec 5
Multiple Airlines Logo
4:35 pm - 11:01 amSDQ-IND
19h 26m1 stop
Multiple Airlines Logo
12:03 pm - 3:23 pmIND-SDQ
26h 20m1 stop
$380Multiple Airlines
Find Deal
Wed, Nov 26 - Sat, Dec 6
Delta Logo
6:35 am - 8:56 pmSDQ-IND
15h 21m1 stop
Delta Logo
12:10 pm - 12:32 amIND-SDQ
11h 22m2 stops
$556Delta
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Thu, Dec 18 - Tue, Jan 6
Delta Logo
2:33 pm - 12:09 amSDQ-IND
10h 36m2 stops
Delta Logo
6:45 am - 6:35 pmIND-SDQ
10h 50m1 stop
$568Delta
Find Deal
Thu, Feb 5 - Fri, Feb 20
American Airlines Logo
6:29 pm - 8:38 amSDQ-IND
15h 09m2 stops
American Airlines Logo
10:23 am - 11:59 pmIND-SDQ
12h 36m2 stops
$589American Airlines
Find Deal
Thu, Feb 5 - Fri, Feb 20
American Airlines Logo
6:00 am - 6:21 pmSDQ-IND
13h 21m2 stops
American Airlines Logo
9:31 pm - 12:21 pmIND-SDQ
13h 50m2 stops
$590American Airlines
Find Deal
Thu, Dec 18 - Tue, Jan 6
United Airlines Logo
6:00 am - 4:49 pmSDQ-IND
11h 49m2 stops
United Airlines Logo
9:05 am - 11:46 pmIND-SDQ
13h 41m2 stops
$651United Airlines
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Thu, Feb 19 - Sun, Feb 22
United Airlines Logo
6:00 am - 2:01 pmSDQ-IND
9h 01m1 stop
United Airlines Logo
7:15 am - 11:46 pmIND-SDQ
15h 31m2 stops
$1,116United Airlines
Find Deal
Mon, Dec 15 - Thu, Dec 25

Spirit Airlines flights from Santo Domingo to Indianapolis

Our best Spirit Airlines deals on Santo Domingo to Indianapolis flight tickets
Spirit Airlines
Nov 20
SDQ4:35 pmSanto Domingo Las Americas
7h 44m
1 stop
IND11:19 pmIndianapolis
Dec 2
IND7:00 amIndianapolis
7h 30m
1 stop
SDQ3:30 pmSanto Domingo Las Americas
$345
Find similar
Spirit Airlines
Nov 20
SDQ4:35 pmSanto Domingo Las Americas
7h 44m
1 stop
IND11:19 pmIndianapolis
Dec 2
IND6:07 pmIndianapolis
20h 23m
2 stops
SDQ3:30 pmSanto Domingo Las Americas
$355
Find similar
Spirit Airlines
Feb 5
SDQ8:01 amSanto Domingo Las Americas
13h 59m
1 stop
IND9:00 pmIndianapolis
Feb 20
IND6:35 amIndianapolis
10h 15m
1 stop
SDQ5:50 pmSanto Domingo Las Americas
$376
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Copa Airlines flights from Santo Domingo to Indianapolis

Our best Copa Airlines deals on Santo Domingo to Indianapolis flight tickets
Copa Airlines
Dec 15
SDQ12:40 pmSanto Domingo Las Americas
22h 44m
2 stops
IND10:24 amIndianapolis
Dec 25
IND7:44 pmIndianapolis
19h 31m
2 stops
SDQ4:15 pmSanto Domingo Las Americas
$908
Find similar
Copa Airlines
Dec 15
SDQ6:39 pmSanto Domingo Las Americas
16h 45m
2 stops
IND10:24 amIndianapolis
Dec 25
IND11:20 amIndianapolis
23h 20m
2 stops
SDQ11:40 amSanto Domingo Las Americas
$1,057
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momondo Fare Finder

 
Customize your flight search to find flights from Santo Domingo to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from Santo Domingo to Indianapolis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santo DomingoIndianapolis

SDQ - IND

SDQIND

Santo Domingo Las Americas

Thu 11/20

4:35 pm-11:19 pm

1 stop7h 44m

Indianapolis

Tue 12/2

7:00 am-3:30 pm

1 stop7h 30m

$345

Santo DomingoIndianapolis

SDQ - IND

SDQIND

Santo Domingo Las Americas

Thu 11/20

4:35 pm-11:19 pm

1 stop7h 44m

Indianapolis

Tue 12/2

6:07 pm-3:30 pm

2 stops20h 23m

$355

Santo DomingoIndianapolis

SDQ - IND

SDQIND

Santo Domingo Las Americas

Mon 11/24

4:35 pm-11:19 pm

1 stop7h 44m

Indianapolis

Fri 12/5

4:10 pm-11:51 am

2 stops18h 41m

$377

Santo DomingoIndianapolis

SDQ - IND

SDQIND

Santo Domingo Las Americas

Wed 11/26

4:35 pm-11:01 am

1 stop19h 26m

Indianapolis

Sat 12/6

12:03 pm-3:23 pm

1 stop26h 20m

$380

Santo DomingoIndianapolis

SDQ - IND

SDQIND

Santo Domingo Las Americas

Thu 12/18

6:35 am-8:56 pm

1 stop15h 21m

Indianapolis

Tue 1/6

12:10 pm-12:32 am

2 stops11h 22m

$556

Santo DomingoIndianapolis

SDQ - IND

SDQIND

Santo Domingo Las Americas

Thu 2/5

2:33 pm-12:09 am

2 stops10h 36m

Indianapolis

Fri 2/20

6:45 am-6:35 pm

1 stop10h 50m

$568

Santo DomingoIndianapolis

SDQ - IND

SDQIND

Santo Domingo Las Americas

Thu 2/5

6:29 pm-8:38 am

2 stops15h 09m

Indianapolis

Fri 2/20

10:23 am-11:59 pm

2 stops12h 36m

$589

Santo DomingoIndianapolis

SDQ - IND

SDQIND

Santo Domingo Las Americas

Thu 12/18

6:00 am-6:21 pm

2 stops13h 21m

Indianapolis

Tue 1/6

9:31 pm-12:21 pm

2 stops13h 50m

$590

Santo DomingoIndianapolis

SDQ - IND

SDQIND

Santo Domingo Las Americas

Thu 2/19

6:00 am-4:49 pm

2 stops11h 49m

Indianapolis

Sun 2/22

9:05 am-11:46 pm

2 stops13h 41m

$651

Santo DomingoIndianapolis

SDQ - IND

SDQIND

Santo Domingo Las Americas

Mon 12/15

6:00 am-2:01 pm

1 stop9h 01m

Indianapolis

Thu 12/25

7:15 am-11:46 pm

2 stops15h 31m

$1,116

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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See travel insights to Indianapolis from

How to get the cheapest flight ticket from Santo Domingo to Indianapolis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santo Domingo and Indianapolis?

What is the cheapest month to fly to Indianapolis?

In general, September is the cheapest month to fly from Santo Domingo to Indianapolis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $341. If you are unable to visit Indianapolis during the month of September, then departing from Santo Domingo during the month November is also very affordable. Most momondo users find prices during this month for around $429.

What is the cheapest day to depart on your flight to Indianapolis?

Our data shows that Thursday is the least expensive day to fly to Indianapolis. Tickets to fly out on this day can be as low as $442. Be sure to avoid booking your departure on a Monday as prices are generally higher than usual. According to our data, the average ticket price to Indianapolis on Monday is $710.

What is the cheapest time of day to depart on your flight to Indianapolis?

Flying to Indianapolis from Santo Domingo in the afternoon is the least expensive time of day to depart. momondo users have found prices as low as $474 when looking at flights departing in the afternoon. If you have a flexible travel schedule, then try to avoid flying at noon when prices are $792 on average. Flights to Indianapolis from Santo Domingo at noon are generally more expensive because this time of day is more convenient for travelers’ schedules.

How have Santo Domingo to Indianapolis flight prices changed over time?

As of November 2025, prices for Santo Domingo to Indianapolis flights are approximately 83% more expensive when compared to flights at the same time last year.

When to book flights from Santo Domingo to Indianapolis

Are you open to changing your travel dates? Check out the ideal times to fly from Santo Domingo to Indianapolis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santo Domingo to Indianapolis (SDQ to IND) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santo Domingo to Indianapolis

Direct flights

None
There are no direct flights from Santo Domingo to Indianapolis. There are no popular flight routes from Santo Domingo to Indianapolis.
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  • How far is Santo Domingo Las Americas to Indianapolis by plane?

    The straight-line distance from Santo Domingo Las Americas to Indianapolis is 1759.1 mi. 7h 01m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Santo Domingo Las Americas Airport to Indianapolis Airport?

    Prices for flights from Santo Domingo Las Americas Airport to Indianapolis Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Santo Domingo Las Americas Airport to Indianapolis Airport?

  • How old do you have to be to fly from Santo Domingo Las Americas Airport to Indianapolis Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santo Domingo Las Americas Airport to Indianapolis Airport.

  • What documentation or ID do you need to fly to Indianapolis Airport?

    The travel and health documents required for your trip to Indianapolis Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Indianapolis Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Santo Domingo to Indianapolis?

Best airlines flying from Santo Domingo to Indianapolis

Compare and see reviews for airlines that fly from Santo Domingo to Indianapolis with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $348Free CancellationRating
6.3
8,115 reviews
Search Spirit Airlines flights
DeltaPriceFrom $552Free CancellationRating
7.9
8,004 reviews
Search Delta flights

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Terre Haute
Bloomington
Kokomo
Muncie
Anderson
Plainfield
Greenwood
Noblesville
Fishers
Carmel
Shelbyville
West Lafayette
Seymour
Franklin
Speedway
Crawfordsville
Brownsburg
Greenfield
Westfield
Mooresville

Why use momondo?

Why should I use momondo to find a flight deal from Santo Domingo to Indianapolis?

It is quick and easy to find Santo Domingo to Indianapolis flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Indianapolis that suits you.

Can I find flights from Santo Domingo to Indianapolis with flexible booking policies on momondo?

All flight searches from Santo Domingo to Indianapolis on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Santo Domingo to Indianapolis?

momondo provides multiple filters to help you find the best flight to Indianapolis from Santo Domingo. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Santo Domingo to Indianapolis right now. Can momondo alert me if prices change?

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