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Cheap flights from Santo Domingo to Indianapolis from $221

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santo Domingo to Indianapolis departing on 5/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Santo Domingo to Indianapolis

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
2:35 pm - 9:49 am
SDQ
-
IND
19h 14m
2 stops
Multiple Airlines Logo
8:36 pm - 5:29 am
IND
-
SDQ
8h 53m
1 stop
$447Multiple Airlines
Fri, May 1 - Tue, May 12
Multiple Airlines Logo
2:35 pm - 11:59 pm
SDQ
-
IND
9h 24m
1 stop
Multiple Airlines Logo
12:14 pm - 9:45 pm
IND
-
SDQ
33h 31m
2 stops
$448Multiple Airlines
Thu, Apr 30 - Mon, May 11
Multiple Airlines Logo
2:35 pm - 10:27 am
SDQ
-
IND
19h 52m
2 stops
Multiple Airlines Logo
8:36 pm - 5:29 am
IND
-
SDQ
8h 53m
1 stop
$449Multiple Airlines
Thu, Apr 30 - Wed, May 13
Multiple Airlines Logo
12:41 pm - 11:21 am
SDQ
-
IND
22h 40m
2 stops
Multiple Airlines Logo
12:26 pm - 2:39 pm
IND
-
SDQ
26h 13m
1 stop
$452Multiple Airlines
Mon, May 4 - Fri, May 8
Multiple Airlines Logo
2:35 pm - 11:59 pm
SDQ
-
IND
9h 24m
1 stop
Multiple Airlines Logo
8:36 pm - 5:29 am
IND
-
SDQ
8h 53m
1 stop
$462Multiple Airlines
Fri, May 1 - Tue, May 12
Multiple Airlines Logo
2:35 pm - 11:59 pm
SDQ
-
IND
9h 24m
1 stop
Multiple Airlines Logo
8:36 pm - 5:29 am
IND
-
SDQ
8h 53m
1 stop
$464Multiple Airlines
Fri, May 1 - Tue, May 12
Multiple Airlines Logo
12:41 pm - 11:21 am
SDQ
-
IND
22h 40m
2 stops
Multiple Airlines Logo
12:26 pm - 7:18 pm
IND
-
SDQ
30h 52m
3 stops
$468Multiple Airlines
Mon, May 4 - Fri, May 8
Multiple Airlines Logo
7:10 pm - 7:41 pm
SDQ
-
IND
24h 31m
1 stop
Multiple Airlines Logo
8:36 pm - 5:29 am
IND
-
SDQ
8h 53m
1 stop
$477Multiple Airlines
Fri, May 29 - Mon, Jun 8
Multiple Airlines Logo
12:41 pm - 7:41 pm
SDQ
-
IND
31h 00m
3 stops
Multiple Airlines Logo
12:26 pm - 7:18 pm
IND
-
SDQ
30h 52m
3 stops
$481Multiple Airlines
Mon, May 4 - Fri, May 8
Multiple Airlines Logo
7:10 pm - 7:41 pm
SDQ
-
IND
24h 31m
1 stop
Multiple Airlines Logo
7:59 pm - 11:06 am
IND
-
SDQ
39h 07m
2 stops
$494Multiple Airlines
Fri, May 29 - Mon, Jun 8

Delta flights from Santo Domingo to Indianapolis

Our best Delta deals on Santo Domingo to Indianapolis flight tickets
Delta
Jul 3
SDQ6:06 amSanto Domingo Las Americas
16h 26m
1 stop
IND10:32 pmIndianapolis
Jul 6
IND6:51 amIndianapolis
17h 51m
1 stop
SDQ12:42 amSanto Domingo Las Americas
$637
Delta
May 7
SDQ6:05 amSanto Domingo Las Americas
12h 48m
2 stops
IND6:53 pmIndianapolis
Jun 16
IND6:51 amIndianapolis
11h 13m
1 stop
SDQ6:04 pmSanto Domingo Las Americas
$641
Delta
Jul 4
SDQ6:06 amSanto Domingo Las Americas
15h 14m
2 stops
IND9:20 pmIndianapolis
Jul 6
IND6:51 amIndianapolis
17h 51m
1 stop
SDQ12:42 amSanto Domingo Las Americas
$661

United Airlines flights from Santo Domingo to Indianapolis

Our best United Airlines deals on Santo Domingo to Indianapolis flight tickets
United Airlines
Apr 16
SDQ6:00 amSanto Domingo Las Americas
17h 39m
2 stops
IND11:39 pmIndianapolis
May 13
IND6:00 amIndianapolis
16h 46m
2 stops
SDQ10:46 pmSanto Domingo Las Americas
$722
United Airlines
Apr 16
SDQ6:00 amSanto Domingo Las Americas
17h 39m
2 stops
IND11:39 pmIndianapolis
May 15
IND9:28 amIndianapolis
28h 42m
2 stops
SDQ2:10 pmSanto Domingo Las Americas
$749
United Airlines
Apr 17
SDQ3:20 pmSanto Domingo Las Americas
25h 32m
2 stops
IND4:52 pmIndianapolis
Apr 20
IND11:05 amIndianapolis
11h 41m
2 stops
SDQ10:46 pmSanto Domingo Las Americas
$801

momondo Fare Finder

 
Customize your flight search to find flights from Santo Domingo to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 9, 2026.
Use the filters below to find and compare flights from Santo Domingo to Indianapolis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santo DomingoIndianapolis

SDQ - IND

SDQIND

Santo Domingo Las Americas

Fri 5/1

2:35 pm-9:49 am

2 stops19h 14m

Indianapolis

Tue 5/12

8:36 pm-5:29 am

1 stop8h 53m

$447

Santo DomingoIndianapolis

SDQ - IND

SDQIND

Santo Domingo Las Americas

Thu 4/30

2:35 pm-11:59 pm

1 stop9h 24m

Indianapolis

Mon 5/11

12:14 pm-9:45 pm

2 stops33h 31m

$448

Santo DomingoIndianapolis

SDQ - IND

SDQIND

Santo Domingo Las Americas

Thu 4/30

2:35 pm-10:27 am

2 stops19h 52m

Indianapolis

Wed 5/13

8:36 pm-5:29 am

1 stop8h 53m

$449

Santo DomingoIndianapolis

SDQ - IND

SDQIND

Santo Domingo Las Americas

Mon 5/4

12:41 pm-11:21 am

2 stops22h 40m

Indianapolis

Fri 5/8

12:26 pm-2:39 pm

1 stop26h 13m

$452
Quickest round-trip

Santo DomingoIndianapolis

SDQ - IND

SDQIND

Santo Domingo Las Americas

Fri 5/1

2:35 pm-11:59 pm

1 stop9h 24m

Indianapolis

Tue 5/12

8:36 pm-5:29 am

1 stop8h 53m

$462

Santo DomingoIndianapolis

SDQ - IND

SDQIND

Santo Domingo Las Americas

Fri 5/1

2:35 pm-11:59 pm

1 stop9h 24m

Indianapolis

Tue 5/12

8:36 pm-5:29 am

1 stop8h 53m

$464

Santo DomingoIndianapolis

SDQ - IND

SDQIND

Santo Domingo Las Americas

Mon 5/4

12:41 pm-11:21 am

2 stops22h 40m

Indianapolis

Fri 5/8

12:26 pm-7:18 pm

3 stops30h 52m

$468

Santo DomingoIndianapolis

SDQ - IND

SDQIND

Santo Domingo Las Americas

Fri 5/29

7:10 pm-7:41 pm

1 stop24h 31m

Indianapolis

Mon 6/8

8:36 pm-5:29 am

1 stop8h 53m

$477

Santo DomingoIndianapolis

SDQ - IND

SDQIND

Santo Domingo Las Americas

Mon 5/4

12:41 pm-7:41 pm

3 stops31h 00m

Indianapolis

Fri 5/8

12:26 pm-7:18 pm

3 stops30h 52m

$481

Santo DomingoIndianapolis

SDQ - IND

SDQIND

Santo Domingo Las Americas

Fri 5/29

7:10 pm-7:41 pm

1 stop24h 31m

Indianapolis

Mon 6/8

7:59 pm-11:06 am

2 stops39h 07m

$494

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Indianapolis from

How to get the cheapest flight ticket from Santo Domingo to Indianapolis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santo Domingo and Indianapolis?

What is the cheapest month to fly to Indianapolis?

In general, September is the cheapest month to fly from Santo Domingo to Indianapolis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $341. If you are unable to visit Indianapolis during the month of September, then departing from Santo Domingo during the month December is also very affordable. Most momondo users find prices during this month for around $449.

How have Santo Domingo to Indianapolis flight prices changed over time?

As of April 2026, prices for Santo Domingo to Indianapolis flights are approximately 8% cheaper when compared to flights at the same time last year.

When to book flights from Santo Domingo to Indianapolis

Are you open to changing your travel dates? Check out the ideal times to fly from Santo Domingo to Indianapolis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santo Domingo to Indianapolis (SDQ to IND) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santo Domingo to Indianapolis

Fastest flight time

9h 38m

Direct flights

None
The fastest flight from Santo Domingo to Indianapolis takes 9h 38m
There are no direct flights from Santo Domingo to Indianapolis. There are no popular flight routes from Santo Domingo to Indianapolis.
Search flight deals

Frequently asked questions about flying from Santo Domingo to Indianapolis

  • How far is Santo Domingo Las Americas to Indianapolis by plane?

    The straight-line distance from Santo Domingo Las Americas to Indianapolis is 1759.1 mi. 9h 38m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Santo Domingo Las Americas Airport to Indianapolis Airport?

    Prices for flights from Santo Domingo Las Americas Airport to Indianapolis Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Santo Domingo Las Americas Airport to Indianapolis Airport?

  • How old do you have to be to fly from Santo Domingo Las Americas Airport to Indianapolis Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santo Domingo Las Americas Airport to Indianapolis Airport.

  • What documentation or ID do you need to fly to Indianapolis Airport?

    The travel and health documents required for your trip to Indianapolis Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Indianapolis Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Santo Domingo to Indianapolis?

Best airlines flying from Santo Domingo to Indianapolis

Compare and see reviews for airlines that fly from Santo Domingo to Indianapolis with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $326Free CancellationRating
6.3
8,606 reviews
Search Spirit Airlines flights
DeltaPriceFrom $553Free CancellationRating
7.9
8,392 reviews
Search Delta flights

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Terre Haute
Bloomington
Kokomo
Muncie
Plainfield
Anderson
Greenwood
Noblesville
Carmel
Fishers
Shelbyville
Franklin
Speedway
Seymour
West Lafayette
Brownsburg
Crawfordsville
Westfield
Greenfield
Mooresville

Why use momondo?

Why should I use momondo to find a flight deal from Santo Domingo to Indianapolis?

It is quick and easy to find Santo Domingo to Indianapolis flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Indianapolis that suits you.

Can I find flights from Santo Domingo to Indianapolis with flexible booking policies on momondo?

All flight searches from Santo Domingo to Indianapolis on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Santo Domingo to Indianapolis?

momondo provides multiple filters to help you find the best flight to Indianapolis from Santo Domingo. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Santo Domingo to Indianapolis right now. Can momondo alert me if prices change?

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