How many flights depart from Santa Ana, California to South Carolina on average per week?

As of July 2026, there are 6 flights per week flying from Santa Ana, California to South Carolina. The most common day of the week flights depart is Mon, with 17% of flights taking off on this day.

What is the cheapest airline that flies from Santa Ana J. Wayne/Orange Cnty to South Carolina?

Southwest, United Airlines, and Breeze Airways are the most popular carriers operating from Santa Ana J. Wayne/Orange Cnty to South Carolina

What airlines fly to South Carolina?

American Airlines, Delta and Breeze Airways are the top three most popular airlines that fly to South Carolina from Santa Ana, California according to our data. American Airlines is the first choice among our users, with 47% of people opting to fly with this airline when traveling to South Carolina. Keep in mind that there are 6 different airlines that fly to South Carolina on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to South Carolina?

Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to South Carolina refresh daily.

How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to South Carolina?

As of July 2026, there are 4 operators available to choose from for flights from Santa Ana J. Wayne/Orange Cnty Airport to South Carolina.

How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to South Carolina?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Santa Ana J. Wayne/Orange Cnty Airport to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$116 Cheap Flights from Santa Ana, California to South Carolina in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Santa Ana, California to South Carolina

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:39 pm - 10:59 am

SNA

CLT

13h 20m

1 stop

7:41 pm - 10:12 am

CLT

SNA

17h 31m

1 stop

$292Frontier

Thu, Aug 27 - Sat, Sep 19

7:03 pm - 11:15 am

SNA

CLT

13h 12m

1 stop

7:41 pm - 10:12 am

CLT

SNA

17h 31m

1 stop

$300Frontier

Thu, Sep 10 - Fri, Sep 11

7:10 am - 4:35 pm

SNA

CLT

6h 25m

1 stop

6:50 am - 1:35 pm

CLT

SNA

9h 45m

2 stops

$316Southwest

Sat, Aug 29 - Tue, Sep 1

6:45 am - 6:20 pm

SNA

CLT

8h 35m

2 stops

6:50 am - 1:35 pm

CLT

SNA

9h 45m

2 stops

$321Southwest

Sat, Aug 29 - Tue, Sep 1

11:10 am - 9:35 pm

SNA

CHS

7h 25m

1 stop

2:54 pm - 8:19 pm

CHS

SNA

8h 25m

1 stop

$323United Airlines

Wed, Aug 12 - Thu, Aug 13

7:05 am - 9:35 pm

SNA

CHS

11h 30m

2 stops

6:30 am - 11:33 am

CHS

SNA

8h 03m

1 stop

$328United Airlines

Wed, Sep 2 - Sat, Sep 5

12:20 pm - 9:46 pm

SNA

CHS

6h 26m

1 stop

12:15 pm - 6:38 pm

CHS

SNA

9h 23m

1 stop

$333Delta

Wed, Dec 2 - Sat, Dec 5

11:45 am - 11:59 pm

SNA

CHS

9h 14m

1 stop

3:14 pm - 8:07 pm

CHS

SNA

7h 53m

1 stop

$341Delta

Tue, Aug 18 - Sat, Sep 5

10:42 am - 10:44 pm

SNA

CAE

9h 02m

1 stop

5:18 pm - 10:29 pm

CAE

SNA

8h 11m

1 stop

$351American Airlines

Sat, Oct 17 - Wed, Oct 21

12:01 pm - 10:47 pm

SNA

SAV

7h 46m

1 stop

12:57 pm - 5:32 pm

SAV

SNA

7h 35m

1 stop

$362American Airlines

Sat, Sep 5 - Fri, Sep 11

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Southwest flights from Santa Ana, California to South Carolina

Our best Southwest deals on Santa Ana, California to South Carolina flight tickets

Southwest

Aug 29

SNA7:10 amSanta Ana J. Wayne/Orange Cnty

6h 25m

1 stop

CLT4:35 pmCharlotte Douglas

Sep 1

CLT6:50 amCharlotte Douglas

9h 45m

2 stops

SNA1:35 pmSanta Ana J. Wayne/Orange Cnty

$316

Southwest

Aug 29

SNA6:45 amSanta Ana J. Wayne/Orange Cnty

8h 35m

2 stops

CLT6:20 pmCharlotte Douglas

Sep 1

CLT6:50 amCharlotte Douglas

9h 45m

2 stops

SNA1:35 pmSanta Ana J. Wayne/Orange Cnty

$321

Southwest

Sep 26

SNA3:45 pmSanta Ana J. Wayne/Orange Cnty

15h 35m

2 stops

CLT10:20 amCharlotte Douglas

Oct 3

CLT10:35 amCharlotte Douglas

8h 40m

1 stop

SNA4:15 pmSanta Ana J. Wayne/Orange Cnty

$322

American Airlines flights from Santa Ana, California to South Carolina

Our best American Airlines deals on Santa Ana, California to South Carolina flight tickets

American Airlines

Oct 17

SNA10:42 amSanta Ana J. Wayne/Orange Cnty

9h 02m

1 stop

CAE10:44 pmColumbia Metropolitan

Oct 21

CAE5:18 pmColumbia Metropolitan

8h 11m

1 stop

SNA10:29 pmSanta Ana J. Wayne/Orange Cnty

$351

American Airlines

Sep 5

SNA12:01 pmSanta Ana J. Wayne/Orange Cnty

7h 46m

1 stop

SAV10:47 pmSavannah/Hilton Head

Sep 11

SAV12:57 pmSavannah/Hilton Head

7h 35m

1 stop

SNA5:32 pmSanta Ana J. Wayne/Orange Cnty

$362

American Airlines

Oct 27

SNA10:42 amSanta Ana J. Wayne/Orange Cnty

9h 10m

1 stop

MYR10:52 pmMyrtle Beach Intl

Nov 3

MYR7:20 amMyrtle Beach Intl

9h 43m

1 stop

SNA2:03 pmSanta Ana J. Wayne/Orange Cnty

$363

momondo Fare Finder

Use the filters below to find and compare flights from Santa Ana, California to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santa AnaCharlotte

SNA - CLT

SNACLT

Santa Ana J. Wayne/Orange Cnty

Thu 8/27

6:39 pm-10:59 am

1 stop13h 20m

Charlotte Douglas

Sat 9/19

7:41 pm-10:12 am

1 stop17h 31m

$292

Santa AnaCharlotte

SNA - CLT

SNACLT

Santa Ana J. Wayne/Orange Cnty

Thu 9/10

7:03 pm-11:15 am

1 stop13h 12m

Charlotte Douglas

Fri 9/11

7:41 pm-10:12 am

1 stop17h 31m

$300

Santa AnaCharlotte

SNA - CLT

SNACLT

Santa Ana J. Wayne/Orange Cnty

Sat 8/29

7:10 am-4:35 pm

1 stop6h 25m

Charlotte Douglas

Tue 9/1

6:50 am-1:35 pm

2 stops9h 45m

$316

Santa AnaCharlotte

SNA - CLT

SNACLT

Santa Ana J. Wayne/Orange Cnty

Sat 8/29

6:45 am-6:20 pm

2 stops8h 35m

Charlotte Douglas

Tue 9/1

6:50 am-1:35 pm

2 stops9h 45m

$321

Santa AnaCharleston

SNA - CHS

SNACHS

Santa Ana J. Wayne/Orange Cnty

Wed 8/12

11:10 am-9:35 pm

1 stop7h 25m

Charleston

Thu 8/13

2:54 pm-8:19 pm

1 stop8h 25m

$323

Santa AnaCharleston

SNA - CHS

SNACHS

Santa Ana J. Wayne/Orange Cnty

Wed 9/2

7:05 am-9:35 pm

2 stops11h 30m

Charleston

Sat 9/5

6:30 am-11:33 am

1 stop8h 03m

$328

Santa AnaCharleston

SNA - CHS

SNACHS

Santa Ana J. Wayne/Orange Cnty

Wed 12/2

12:20 pm-9:46 pm

1 stop6h 26m

Charleston

Sat 12/5

12:15 pm-6:38 pm

1 stop9h 23m

$333

Santa AnaCharleston

SNA - CHS

SNACHS

Santa Ana J. Wayne/Orange Cnty

Tue 8/18

11:45 am-11:59 pm

1 stop9h 14m

Charleston

Sat 9/5

3:14 pm-8:07 pm

1 stop7h 53m

$341

Santa AnaColumbia

SNA - CAE

SNACAE

Santa Ana J. Wayne/Orange Cnty

Sat 10/17

10:42 am-10:44 pm

1 stop9h 02m

Columbia Metropolitan

Wed 10/21

5:18 pm-10:29 pm

1 stop8h 11m

$351

Quickest round-trip

Santa AnaSavannah

SNA - SAV

SNASAV

Santa Ana J. Wayne/Orange Cnty

Sat 9/5

12:01 pm-10:47 pm

1 stop7h 46m

Savannah/Hilton Head

Fri 9/11

12:57 pm-5:32 pm

1 stop7h 35m

$362

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Santa Ana, California to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Santa Ana, California is in September. Flight prices, which tend to average around $437, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of September, then book flights to South Carolina from Santa Ana, California during January instead. Flights to South Carolina in January, while not as cheap as those in September, still average around $466.

Can stopping save me money on Santa Ana, California to South Carolina flights?

You could potentially save up to 29% on your flight if you consider stops on a Santa Ana, California to South Carolina flight.

Cheap Santa Ana, California to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana, California to South Carolina

Fastest flight time	4h 45m
Direct flights	Every day
Airports in South Carolina	57 airports

The fastest flight from Santa Ana, California to South Carolina takes 4h 45m

Direct flights go from Santa Ana, California to South Carolina every day.

There are 57 airports in South Carolina. From Santa Ana, California there are direct flights to Charlotte Douglas (CLT).

Search flight deals

Frequently asked questions about flying from Santa Ana, California to South Carolina

When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to South Carolina?
Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to South Carolina refresh daily.
How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to South Carolina?
As of July 2026, there are 4 operators available to choose from for flights from Santa Ana J. Wayne/Orange Cnty Airport to South Carolina.
How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to South Carolina?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Santa Ana J. Wayne/Orange Cnty Airport to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Santa Ana, California to South Carolina

Compare and see reviews for airlines that fly from Santa Ana, California to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $303	Free Cancellation	Rating 7.1 11,832 reviews	Search American Airlines flights
Southwest	PriceFrom $327	Free Cancellation	Rating 8.0 4,238 reviews	Search Southwest flights
Delta	PriceFrom $332	Free Cancellation	Rating 7.8 8,479 reviews	Search Delta flights
United Airlines	PriceFrom $336	Free Cancellation	Rating 7.4 10,024 reviews	Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to South Carolina?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Santa Ana to South Carolina. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Santa Ana to South Carolina with flexible booking policies on momondo?

Flights from Santa Ana to South Carolina with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Santa Ana to South Carolina?

momondo helps you find the best flight between Santa Ana and South Carolina by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Santa Ana to South Carolina right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Santa Ana to South Carolina flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.