What is the cheapest airline that flies from Santa Ana J. Wayne/Orange Cnty to South Carolina?

Spirit Airlines, American Airlines, and United Airlines are the most popular carriers operating from Santa Ana J. Wayne/Orange Cnty to South Carolina

What airlines fly to South Carolina?

American Airlines, Delta and Breeze Airways are the top three most popular airlines that fly to South Carolina from Santa Ana, California according to our data. American Airlines is the first choice among our users, with 50% of people opting to fly with this airline when traveling to South Carolina. Keep in mind that there are 7 different airlines that fly to South Carolina on a routine basis, so you have a few additional options to choose from.

How many flights depart from Santa Ana, California to South Carolina on average per week?

As of March 2026, there are 3 flights per week flying from Santa Ana, California to South Carolina. The most common day of the week flights depart is Thu, with 33% of flights taking off on this day.

When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to South Carolina?

Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to South Carolina refresh daily.

How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to South Carolina?

As of March 2026, there are 4 operators available to choose from for flights from Santa Ana J. Wayne/Orange Cnty Airport to South Carolina.

How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to South Carolina?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Santa Ana J. Wayne/Orange Cnty Airport to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$83 Cheap Flights from Santa Ana to South Carolina in 2026

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Find the cheapest flights from Santa Ana, California to South Carolina

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

2:53 pm - 8:21 am

SNA

CLT

14h 28m

2 stops

1:20 pm - 9:53 am

CLT

SNA

23h 33m

2 stops

$242Spirit Airlines

Tue, Apr 7 - Mon, Apr 13

2:53 pm - 11:08 am

SNA

CHS

17h 15m

2 stops

12:05 pm - 9:45 pm

CHS

SNA

12h 40m

2 stops

$248Spirit Airlines

Tue, Apr 14 - Tue, May 5

2:35 pm - 12:45 am

SNA

CLT

7h 10m

1 stop

6:35 am - 11:11 am

CLT

SNA

7h 36m

1 stop

$259United Airlines

Wed, May 6 - Tue, May 12

12:15 pm - 9:59 pm

SNA

CHS

6h 44m

1 stop

4:01 pm - 8:44 pm

CHS

SNA

7h 43m

1 stop

$331United Airlines

Tue, Apr 14 - Tue, May 5

9:20 pm - 12:12 pm

SNA

CHS

11h 52m

1 stop

1:17 pm - 6:33 pm

CHS

SNA

8h 16m

1 stop

$341Delta

Sat, May 16 - Sat, May 23

12:52 pm - 10:45 pm

SNA

GSP

6h 53m

1 stop

7:00 am - 1:49 pm

GSP

SNA

9h 49m

1 stop

$367American Airlines

Tue, Mar 31 - Tue, Apr 14

10:38 am - 10:30 pm

SNA

CAE

8h 52m

1 stop

4:18 pm - 8:00 pm

CAE

SNA

6h 42m

1 stop

$369American Airlines

Wed, Aug 26 - Tue, Sep 1

10:35 am - 7:15 pm

SNA

SAV

5h 40m

1 stop

6:40 am - 1:55 pm

SAV

SNA

10h 15m

2 stops

$372Southwest

Wed, Apr 1 - Tue, Apr 7

10:35 am - 10:40 pm

SNA

GSP

9h 05m

2 stops

12:50 pm - 7:05 pm

GSP

SNA

9h 15m

2 stops

$377Southwest

Tue, Mar 31 - Tue, Apr 7

7:15 pm - 9:33 am

SNA

MYR

11h 18m

2 stops

12:50 pm - 10:28 pm

MYR

SNA

12h 38m

2 stops

$407Delta

Thu, Apr 9 - Wed, Apr 15

Spirit Airlines flights from Santa Ana, California to South Carolina

Our best Spirit Airlines deals on Santa Ana, California to South Carolina flight tickets

Spirit Airlines

Apr 7

SNA2:53 pmSanta Ana J. Wayne/Orange Cnty

14h 28m

2 stops

CLT8:21 amCharlotte Douglas

Apr 13

CLT1:20 pmCharlotte Douglas

23h 33m

2 stops

SNA9:53 amSanta Ana J. Wayne/Orange Cnty

$242

Spirit Airlines

Apr 14

SNA2:53 pmSanta Ana J. Wayne/Orange Cnty

17h 15m

2 stops

CHS11:08 amCharleston

May 5

CHS12:05 pmCharleston

12h 40m

2 stops

SNA9:45 pmSanta Ana J. Wayne/Orange Cnty

$248

Spirit Airlines

Apr 8

SNA2:53 pmSanta Ana J. Wayne/Orange Cnty

14h 28m

2 stops

CLT8:21 amCharlotte Douglas

Apr 10

CLT1:20 pmCharlotte Douglas

23h 33m

2 stops

SNA9:53 amSanta Ana J. Wayne/Orange Cnty

$258

American Airlines flights from Santa Ana, California to South Carolina

Our best American Airlines deals on Santa Ana, California to South Carolina flight tickets

American Airlines

Apr 18

SNA7:45 amSanta Ana J. Wayne/Orange Cnty

8h 44m

1 stop

CHS7:29 pmCharleston

Apr 23

CHS4:41 pmCharleston

9h 04m

1 stop

SNA10:45 pmSanta Ana J. Wayne/Orange Cnty

$365

American Airlines

Mar 31

SNA12:52 pmSanta Ana J. Wayne/Orange Cnty

6h 53m

1 stop

GSP10:45 pmGreenville

Apr 14

GSP7:00 amGreenville

9h 49m

1 stop

SNA1:49 pmSanta Ana J. Wayne/Orange Cnty

$367

American Airlines

Aug 26

SNA10:38 amSanta Ana J. Wayne/Orange Cnty

8h 52m

1 stop

CAE10:30 pmColumbia Metropolitan

Sep 1

CAE4:18 pmColumbia Metropolitan

6h 42m

1 stop

SNA8:00 pmSanta Ana J. Wayne/Orange Cnty

$369

momondo Fare Finder

Use the filters below to find and compare flights from Santa Ana, California to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santa AnaCharlotte

SNA - CLT

SNACLT

Santa Ana J. Wayne/Orange Cnty

Tue 4/7

2:53 pm-8:21 am

2 stops14h 28m

Charlotte Douglas

Mon 4/13

1:20 pm-9:53 am

2 stops23h 33m

$242

Santa AnaCharleston

SNA - CHS

SNACHS

Santa Ana J. Wayne/Orange Cnty

Tue 4/14

2:53 pm-11:08 am

2 stops17h 15m

Charleston

Tue 5/5

12:05 pm-9:45 pm

2 stops12h 40m

$248

Santa AnaCharlotte

SNA - CLT

SNACLT

Santa Ana J. Wayne/Orange Cnty

Wed 5/6

2:35 pm-12:45 am

1 stop7h 10m

Charlotte Douglas

Tue 5/12

6:35 am-11:11 am

1 stop7h 36m

$259

Quickest round-trip

Santa AnaCharleston

SNA - CHS

SNACHS

Santa Ana J. Wayne/Orange Cnty

Tue 4/14

12:15 pm-9:59 pm

1 stop6h 44m

Charleston

Tue 5/5

4:01 pm-8:44 pm

1 stop7h 43m

$331

Santa AnaCharleston

SNA - CHS

SNACHS

Santa Ana J. Wayne/Orange Cnty

Sat 5/16

9:20 pm-12:12 pm

1 stop11h 52m

Charleston

Sat 5/23

1:17 pm-6:33 pm

1 stop8h 16m

$341

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

Tue 3/31

12:52 pm-10:45 pm

1 stop6h 53m

Greenville

Tue 4/14

7:00 am-1:49 pm

1 stop9h 49m

$367

Santa AnaColumbia

SNA - CAE

SNACAE

Santa Ana J. Wayne/Orange Cnty

Wed 8/26

10:38 am-10:30 pm

1 stop8h 52m

Columbia Metropolitan

Tue 9/1

4:18 pm-8:00 pm

1 stop6h 42m

$369

Santa AnaSavannah

SNA - SAV

SNASAV

Santa Ana J. Wayne/Orange Cnty

Wed 4/1

10:35 am-7:15 pm

1 stop5h 40m

Savannah/Hilton Head

Tue 4/7

6:40 am-1:55 pm

2 stops10h 15m

$372

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

Tue 3/31

10:35 am-10:40 pm

2 stops9h 05m

Greenville

Tue 4/7

12:50 pm-7:05 pm

2 stops9h 15m

$377

Santa AnaMyrtle Beach

SNA - MYR

SNAMYR

Santa Ana J. Wayne/Orange Cnty

Thu 4/9

7:15 pm-9:33 am

2 stops11h 18m

Myrtle Beach Intl

Wed 4/15

12:50 pm-10:28 pm

2 stops12h 38m

$407

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Santa Ana, California to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Santa Ana, California is in July. Flight prices, which tend to average around $407, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of July, then book flights to South Carolina from Santa Ana, California during August instead. Flights to South Carolina in August, while not as cheap as those in July, still average around $419.

How far in advance should I book a flight to South Carolina?

You are more likely to see cheaper flights to South Carolina from Santa Ana, California when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $477 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Santa Ana, California for as low as $331 on momondo.

Can stopping save me money on Santa Ana, California to South Carolina flights?

You could potentially save up to 39% on your flight if you consider stops on a Santa Ana, California to South Carolina flight.

Cheap Santa Ana, California to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana, California to South Carolina

Fastest flight time	4h 37m
Direct flights	Every day
Airports in South Carolina	57 airports

The fastest flight from Santa Ana, California to South Carolina takes 4h 37m

Direct flights go from Santa Ana, California to South Carolina every day.

There are 57 airports in South Carolina. From Santa Ana, California there are direct flights to Charlotte Douglas (CLT).

Search flight deals

When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to South Carolina?
Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to South Carolina refresh daily.
How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to South Carolina?
As of March 2026, there are 4 operators available to choose from for flights from Santa Ana J. Wayne/Orange Cnty Airport to South Carolina.
How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to South Carolina?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Santa Ana J. Wayne/Orange Cnty Airport to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Santa Ana, California to South Carolina

Compare and see reviews for airlines that fly from Santa Ana, California to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $300	Free Cancellation	Rating 7.4 9,389 reviews	Search United Airlines flights
American Airlines	PriceFrom $300	Free Cancellation	Rating 7.1 11,381 reviews	Search American Airlines flights
Delta	PriceFrom $313	Free Cancellation	Rating 7.9 8,248 reviews	Search Delta flights
Southwest	PriceFrom $327	Free Cancellation	Rating 8.0 4,307 reviews	Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to South Carolina?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Santa Ana to South Carolina. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Santa Ana to South Carolina with flexible booking policies on momondo?

Flights from Santa Ana to South Carolina with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Santa Ana to South Carolina?

momondo helps you find the best flight between Santa Ana and South Carolina by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Santa Ana to South Carolina right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Santa Ana to South Carolina flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.