How many flights depart from Santa Ana, California to South Carolina on average per week?

As of April 2026, there are 7 flights per week flying from Santa Ana, California to South Carolina. The most common day of the week flights depart is Mon, with 14% of flights taking off on this day.

What is the cheapest airline that flies from Santa Ana J. Wayne/Orange Cnty to South Carolina?

Frontier, Breeze Airways, and Delta are the most popular carriers operating from Santa Ana J. Wayne/Orange Cnty to South Carolina

What airlines fly to South Carolina?

American Airlines, Delta and Breeze Airways are the top three most popular airlines that fly to South Carolina from Santa Ana, California according to our data. American Airlines is the first choice among our users, with 49% of people opting to fly with this airline when traveling to South Carolina. Keep in mind that there are 7 different airlines that fly to South Carolina on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to South Carolina?

Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to South Carolina refresh daily.

How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to South Carolina?

As of April 2026, there are 4 operators available to choose from for flights from Santa Ana J. Wayne/Orange Cnty Airport to South Carolina.

How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to South Carolina?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Santa Ana J. Wayne/Orange Cnty Airport to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$110 Cheap Flights from Santa Ana to South Carolina in 2026

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Find the cheapest flights from Santa Ana, California to South Carolina

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

8:10 pm - 7:15 am

SNA

CLT

8h 05m

1 stop

10:14 pm - 8:09 am

CLT

SNA

12h 55m

1 stop

$224Frontier

Sat, Jul 18 - Wed, Jul 22

8:10 pm - 6:59 am

SNA

CLT

7h 49m

1 stop

2:10 pm - 12:19 pm

CLT

SNA

25h 09m

1 stop

$246Frontier

Fri, May 29 - Thu, Jun 4

7:30 am - 6:20 pm

SNA

CHS

7h 50m

1 stop

1:15 pm - 8:55 pm

CHS

SNA

10h 40m

1 stop

$260Southwest

Tue, Sep 1 - Tue, Sep 8

6:45 am - 7:45 pm

SNA

CHS

10h 00m

2 stops

1:15 pm - 8:55 pm

CHS

SNA

10h 40m

1 stop

$266Southwest

Tue, Sep 1 - Tue, Sep 8

2:00 pm - 11:58 pm

SNA

MYR

6h 58m

1 stop

6:00 am - 12:40 pm

MYR

SNA

9h 40m

1 stop

$383Delta

Tue, May 19 - Tue, May 26

7:05 pm - 9:25 am

SNA

CAE

11h 20m

2 stops

1:20 pm - 6:20 pm

CAE

SNA

8h 00m

1 stop

$385Delta

Thu, Aug 27 - Wed, Sep 2

9:14 pm - 10:44 am

SNA

GSP

10h 30m

1 stop

4:15 pm - 9:50 pm

GSP

SNA

8h 35m

1 stop

$393United Airlines

Tue, Aug 11 - Wed, Aug 12

6:30 pm - 9:50 am

SNA

GSP

12h 20m

2 stops

4:15 pm - 9:50 pm

GSP

SNA

8h 35m

1 stop

$399United Airlines

Tue, Aug 11 - Wed, Aug 12

10:30 am - 10:57 pm

SNA

GSP

9h 27m

1 stop

6:29 am - 10:56 am

GSP

SNA

7h 27m

1 stop

$413American Airlines

Sat, May 30 - Sat, Jun 6

12:01 pm - 10:52 pm

SNA

CAE

7h 51m

1 stop

12:46 pm - 6:10 pm

CAE

SNA

8h 24m

1 stop

$420American Airlines

Thu, Aug 27 - Wed, Sep 2

Frontier flights from Santa Ana, California to South Carolina

Our best Frontier deals on Santa Ana, California to South Carolina flight tickets

Frontier

Jul 18

SNA8:10 pmSanta Ana J. Wayne/Orange Cnty

8h 05m

1 stop

CLT7:15 amCharlotte Douglas

Jul 22

CLT10:14 pmCharlotte Douglas

12h 55m

1 stop

SNA8:09 amSanta Ana J. Wayne/Orange Cnty

$224

Frontier

May 29

SNA8:10 pmSanta Ana J. Wayne/Orange Cnty

7h 49m

1 stop

CLT6:59 amCharlotte Douglas

Jun 4

CLT2:10 pmCharlotte Douglas

25h 09m

1 stop

SNA12:19 pmSanta Ana J. Wayne/Orange Cnty

$246

Frontier

Jul 20

SNA6:38 pmSanta Ana J. Wayne/Orange Cnty

13h 40m

1 stop

CLT11:18 amCharlotte Douglas

Jul 24

CLT12:13 pmCharlotte Douglas

8h 40m

1 stop

SNA5:53 pmSanta Ana J. Wayne/Orange Cnty

$250

Spirit Airlines flights from Santa Ana, California to South Carolina

Our best Spirit Airlines deals on Santa Ana, California to South Carolina flight tickets

Spirit Airlines

May 4

SNA4:33 pmSanta Ana J. Wayne/Orange Cnty

18h 38m

3 stops

CLT2:11 pmCharlotte Douglas

May 8

CLT12:48 pmCharlotte Douglas

29h 50m

3 stops

SNA3:38 pmSanta Ana J. Wayne/Orange Cnty

$408

Spirit Airlines

May 4

SNA4:33 pmSanta Ana J. Wayne/Orange Cnty

23h 19m

3 stops

CLT6:52 pmCharlotte Douglas

May 6

CLT6:49 pmCharlotte Douglas

30h 19m

3 stops

SNA10:08 pmSanta Ana J. Wayne/Orange Cnty

$419

Spirit Airlines

Apr 30

SNA3:23 pmSanta Ana J. Wayne/Orange Cnty

20h 13m

3 stops

CLT2:36 pmCharlotte Douglas

May 1

CLT9:54 pmCharlotte Douglas

26h 51m

3 stops

SNA9:45 pmSanta Ana J. Wayne/Orange Cnty

$472

momondo Fare Finder

Use the filters below to find and compare flights from Santa Ana, California to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santa AnaCharlotte

SNA - CLT

SNACLT

Santa Ana J. Wayne/Orange Cnty

Sat 7/18

8:10 pm-7:15 am

1 stop8h 05m

Charlotte Douglas

Wed 7/22

10:14 pm-8:09 am

1 stop12h 55m

$224

Santa AnaCharlotte

SNA - CLT

SNACLT

Santa Ana J. Wayne/Orange Cnty

Fri 5/29

8:10 pm-6:59 am

1 stop7h 49m

Charlotte Douglas

Thu 6/4

2:10 pm-12:19 pm

1 stop25h 09m

$246

Santa AnaCharleston

SNA - CHS

SNACHS

Santa Ana J. Wayne/Orange Cnty

Tue 9/1

7:30 am-6:20 pm

1 stop7h 50m

Charleston

Tue 9/8

1:15 pm-8:55 pm

1 stop10h 40m

$260

Santa AnaCharleston

SNA - CHS

SNACHS

Santa Ana J. Wayne/Orange Cnty

Tue 9/1

6:45 am-7:45 pm

2 stops10h 00m

Charleston

Tue 9/8

1:15 pm-8:55 pm

1 stop10h 40m

$266

Santa AnaMyrtle Beach

SNA - MYR

SNAMYR

Santa Ana J. Wayne/Orange Cnty

Tue 5/19

2:00 pm-11:58 pm

1 stop6h 58m

Myrtle Beach Intl

Tue 5/26

6:00 am-12:40 pm

1 stop9h 40m

$383

Santa AnaColumbia

SNA - CAE

SNACAE

Santa Ana J. Wayne/Orange Cnty

Thu 8/27

7:05 pm-9:25 am

2 stops11h 20m

Columbia Metropolitan

Wed 9/2

1:20 pm-6:20 pm

1 stop8h 00m

$385

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

Tue 8/11

9:14 pm-10:44 am

1 stop10h 30m

Greenville

Wed 8/12

4:15 pm-9:50 pm

1 stop8h 35m

$393

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

Tue 8/11

6:30 pm-9:50 am

2 stops12h 20m

Greenville

Wed 8/12

4:15 pm-9:50 pm

1 stop8h 35m

$399

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

Sat 5/30

10:30 am-10:57 pm

1 stop9h 27m

Greenville

Sat 6/6

6:29 am-10:56 am

1 stop7h 27m

$413

Quickest round-trip

Santa AnaColumbia

SNA - CAE

SNACAE

Santa Ana J. Wayne/Orange Cnty

Thu 8/27

12:01 pm-10:52 pm

1 stop7h 51m

Columbia Metropolitan

Wed 9/2

12:46 pm-6:10 pm

1 stop8h 24m

$420

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Santa Ana, California to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Santa Ana, California is in July. Flight prices, which tend to average around $416, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of July, then book flights to South Carolina from Santa Ana, California during June instead. Flights to South Carolina in June, while not as cheap as those in July, still average around $422.

Can stopping save me money on Santa Ana, California to South Carolina flights?

You could potentially save up to 35% on your flight if you consider stops on a Santa Ana, California to South Carolina flight.

Cheap Santa Ana, California to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana, California to South Carolina

Fastest flight time	4h 36m
Direct flights	Every day
Airports in South Carolina	57 airports

The fastest flight from Santa Ana, California to South Carolina takes 4h 36m

Direct flights go from Santa Ana, California to South Carolina every day.

There are 57 airports in South Carolina. From Santa Ana, California there are direct flights to Charlotte Douglas (CLT).

Search flight deals

Frequently asked questions about flying from Santa Ana, California to South Carolina

When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to South Carolina?
Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to South Carolina refresh daily.
How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to South Carolina?
As of April 2026, there are 4 operators available to choose from for flights from Santa Ana J. Wayne/Orange Cnty Airport to South Carolina.
How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to South Carolina?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Santa Ana J. Wayne/Orange Cnty Airport to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Santa Ana, California to South Carolina

Compare and see reviews for airlines that fly from Santa Ana, California to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $300	Free Cancellation	Rating 7.1 11,625 reviews	Search American Airlines flights
Delta	PriceFrom $313	Free Cancellation	Rating 7.9 8,422 reviews	Search Delta flights
Southwest	PriceFrom $327	Free Cancellation	Rating 8.0 4,330 reviews	Search Southwest flights
United Airlines	PriceFrom $330	Free Cancellation	Rating 7.4 9,607 reviews	Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to South Carolina?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Santa Ana to South Carolina. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Santa Ana to South Carolina with flexible booking policies on momondo?

Flights from Santa Ana to South Carolina with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Santa Ana to South Carolina?

momondo helps you find the best flight between Santa Ana and South Carolina by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Santa Ana to South Carolina right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Santa Ana to South Carolina flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.