What airlines fly to South America?

LATAM Airlines, Copa Airlines and Avianca are the top three most popular airlines that fly to South America from Santa Ana, California according to our data. LATAM Airlines is the first choice among our users, with 45% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 9 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Santa Ana J. Wayne/Orange Cnty to South America?

United Airlines, American Airlines, and Delta are the most popular carriers operating from Santa Ana J. Wayne/Orange Cnty to South America

When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to South America?

Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to South America are refreshed on a daily basis.

How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to South America?

The number of operators available for flights from Santa Ana J. Wayne/Orange Cnty Airport to South America is 3 as of September 2026.

How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to South America?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santa Ana J. Wayne/Orange Cnty Airport to South America.

What documentation or ID do you need to fly to South America?

The necessary travel and health documents for your South America trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$275 Cheap Flights from Santa Ana, California to South America in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Santa Ana, California to South America

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

8:00 am - 11:30 pmSNA Santa Ana J. Wayne/Orange Cnty-BOG Bogotá El Dorado

12h 30m1 stop Dallas/Fort Worth

11:55 pm - 8:28 amBOG Bogotá El Dorado-SNA Santa Ana J. Wayne/Orange Cnty

11h 33m1 stop Dallas/Fort Worth

$588American Airlines

Tue, Nov 3 - Sat, Nov 21

6:45 am - 11:30 pmSNA Santa Ana J. Wayne/Orange Cnty-BOG Bogotá El Dorado

13h 45m1 stop Dallas/Fort Worth

11:55 pm - 8:28 amBOG Bogotá El Dorado-SNA Santa Ana J. Wayne/Orange Cnty

11h 33m1 stop Dallas/Fort Worth

$588American Airlines

Tue, Nov 3 - Sat, Nov 21

6:36 pm - 10:35 pmSNA Santa Ana J. Wayne/Orange Cnty-BOG Bogotá El Dorado

24h 59m2 stops San Francisco Houston George Bush Intcntl

8:15 am - 8:46 amBOG Bogotá El Dorado-SNA Santa Ana J. Wayne/Orange Cnty

27h 31m2 stops Houston George Bush Intcntl San Francisco

$593United Airlines

Tue, Nov 3 - Sat, Nov 21

6:45 am - 11:30 pmSNA Santa Ana J. Wayne/Orange Cnty-BOG Bogotá El Dorado

13h 45m1 stop Dallas/Fort Worth

11:55 pm - 3:42 pmBOG Bogotá El Dorado-SNA Santa Ana J. Wayne/Orange Cnty

18h 47m2 stops Dallas/Fort Worth Phoenix Sky Harbor Intl

$593American Airlines

Tue, Nov 3 - Sat, Nov 21

8:05 am - 12:30 amSNA Santa Ana J. Wayne/Orange Cnty-UIO Quito Mariscal Sucr

13h 25m1 stop Houston George Bush Intcntl

1:35 am - 1:51 pmUIO Quito Mariscal Sucr-SNA Santa Ana J. Wayne/Orange Cnty

15h 16m1 stop Houston George Bush Intcntl

$633United Airlines

Sat, Nov 14 - Mon, Nov 23

12:08 pm - 12:30 amSNA Santa Ana J. Wayne/Orange Cnty-UIO Quito Mariscal Sucr

9h 22m1 stop Houston George Bush Intcntl

1:35 am - 1:51 pmUIO Quito Mariscal Sucr-SNA Santa Ana J. Wayne/Orange Cnty

15h 16m1 stop Houston George Bush Intcntl

$633United Airlines

Tue, Nov 17 - Mon, Nov 23

7:50 pm - 1:10 pmSNA Santa Ana J. Wayne/Orange Cnty-MDE Medellín Jose Maria Cordova Intl

14h 20m2 stops San Francisco San Salvador El Salvador Intl

2:10 pm - 8:42 amMDE Medellín Jose Maria Cordova Intl-SNA Santa Ana J. Wayne/Orange Cnty

21h 32m2 stops San Salvador El Salvador Intl San Francisco

$648Multiple Airlines

Mon, Nov 23 - Mon, Dec 14

7:59 pm - 1:10 pmSNA Santa Ana J. Wayne/Orange Cnty-MDE Medellín Jose Maria Cordova Intl

14h 11m2 stops San Francisco San Salvador El Salvador Intl

2:10 pm - 8:42 amMDE Medellín Jose Maria Cordova Intl-SNA Santa Ana J. Wayne/Orange Cnty

21h 32m2 stops San Salvador El Salvador Intl San Francisco

$648Multiple Airlines

Tue, Nov 17 - Thu, Dec 10

11:38 am - 11:35 pmSNA Santa Ana J. Wayne/Orange Cnty-CTG Cartagena Rafael Nunez

33h 57m2 stops Atlanta Hartsfield-Jackson Bogotá El Dorado

2:30 pm - 12:44 pmCTG Cartagena Rafael Nunez-SNA Santa Ana J. Wayne/Orange Cnty

24h 14m1 stop Atlanta Hartsfield-Jackson

$781Delta

Sun, Oct 18 - Thu, Oct 29

12:20 pm - 2:10 pmSNA Santa Ana J. Wayne/Orange Cnty-CTG Cartagena Rafael Nunez

22h 50m1 stop Atlanta Hartsfield-Jackson

3:25 pm - 12:56 pmCTG Cartagena Rafael Nunez-SNA Santa Ana J. Wayne/Orange Cnty

24h 31m1 stop Atlanta Hartsfield-Jackson

$808Delta

Sat, Jan 30 - Sat, Feb 6

Cheap last minute flights

Enter your travel dates to find the best prices.

3:10 pm - 11:25 pmSNA Santa Ana J. Wayne/Orange Cnty-UIO Quito Mariscal Sucr

30h 15m1 stop Houston George Bush Intcntl

12:35 am - 8:51 pmUIO Quito Mariscal Sucr-SNA Santa Ana J. Wayne/Orange Cnty

22h 16m1 stop Houston George Bush Intcntl

$727Multiple Airlines

Wed, Sep 2 - Fri, Sep 4

8:13 am - 7:20 pmSNA Santa Ana J. Wayne/Orange Cnty-BOG Bogotá El Dorado

9h 07m1 stop Houston George Bush Intcntl

12:14 am - 2:02 pmBOG Bogotá El Dorado-SNA Santa Ana J. Wayne/Orange Cnty

15h 48m1 stop Houston George Bush Intcntl

$800Multiple Airlines

Sat, Sep 5 - Fri, Sep 11

3:10 pm - 11:25 pmSNA Santa Ana J. Wayne/Orange Cnty-UIO Quito Mariscal Sucr

30h 15m1 stop Houston George Bush Intcntl

12:35 am - 2:02 pmUIO Quito Mariscal Sucr-SNA Santa Ana J. Wayne/Orange Cnty

15h 27m1 stop Houston George Bush Intcntl

$821Multiple Airlines

Wed, Sep 2 - Sat, Sep 5

3:10 pm - 11:25 pmSNA Santa Ana J. Wayne/Orange Cnty-UIO Quito Mariscal Sucr

30h 15m1 stop Houston George Bush Intcntl

12:35 am - 2:02 pmUIO Quito Mariscal Sucr-SNA Santa Ana J. Wayne/Orange Cnty

15h 27m1 stop Houston George Bush Intcntl

$847Multiple Airlines

Wed, Sep 2 - Sat, Sep 5

7:05 pm - 1:40 pmSNA Santa Ana J. Wayne/Orange Cnty-BOG Bogotá El Dorado

16h 35m2 stops Salt Lake City Atlanta Hartsfield-Jackson

2:55 pm - 10:26 amBOG Bogotá El Dorado-SNA Santa Ana J. Wayne/Orange Cnty

21h 31m2 stops Atlanta Hartsfield-Jackson Detroit Metropolitan Wayne County

$968Delta

Tue, Sep 1 - Tue, Sep 8

6:45 am - 7:15 pmSNA Santa Ana J. Wayne/Orange Cnty-BOG Bogotá El Dorado

10h 30m1 stop Atlanta Hartsfield-Jackson

2:55 pm - 10:26 amBOG Bogotá El Dorado-SNA Santa Ana J. Wayne/Orange Cnty

21h 31m2 stops Atlanta Hartsfield-Jackson Detroit Metropolitan Wayne County

$968Delta

Tue, Sep 1 - Tue, Sep 8

8:13 am - 7:20 pmSNA Santa Ana J. Wayne/Orange Cnty-BOG Bogotá El Dorado

9h 07m1 stop Houston George Bush Intcntl

12:14 am - 2:02 pmBOG Bogotá El Dorado-SNA Santa Ana J. Wayne/Orange Cnty

15h 48m1 stop Houston George Bush Intcntl

$1,047United Airlines

Tue, Sep 1 - Mon, Sep 7

12:03 pm - 4:54 amSNA Santa Ana J. Wayne/Orange Cnty-BOG Bogotá El Dorado

14h 51m1 stop Houston George Bush Intcntl

12:14 am - 8:51 pmBOG Bogotá El Dorado-SNA Santa Ana J. Wayne/Orange Cnty

22h 37m2 stops Houston George Bush Intcntl San Francisco

$1,047United Airlines

Tue, Sep 1 - Mon, Sep 7

8:13 am - 11:00 pmSNA Santa Ana J. Wayne/Orange Cnty-LIM Lima J Chavez Intl

12h 47m1 stop Houston George Bush Intcntl

12:55 am - 8:51 pmLIM Lima J Chavez Intl-SNA Santa Ana J. Wayne/Orange Cnty

21h 56m2 stops Houston George Bush Intcntl San Francisco

$1,119United Airlines

Sat, Sep 5 - Fri, Sep 18

2:00 pm - 8:55 pmSNA Santa Ana J. Wayne/Orange Cnty-SCL Santiago Arturo Merino Benitez

27h 55m2 stops Atlanta Hartsfield-Jackson Lima J Chavez Intl

8:55 pm - 6:29 pmSCL Santiago Arturo Merino Benitez-SNA Santa Ana J. Wayne/Orange Cnty

25h 34m2 stops Lima J Chavez Intl Atlanta Hartsfield-Jackson

$1,157Delta

Wed, Sep 2 - Sun, Sep 20

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American Airlines flights from Santa Ana, California to South America

Our best American Airlines deals on Santa Ana, California to South America flight tickets

American Airlines

Nov 3

SNA8:00 amSanta Ana J. Wayne/Orange Cnty

12h 30m

1 stop

BOG11:30 pmBogotá El Dorado

Nov 21

BOG11:55 pmBogotá El Dorado

11h 33m

1 stop

SNA8:28 amSanta Ana J. Wayne/Orange Cnty

$588

American Airlines

Sep 27

SNA8:45 amSanta Ana J. Wayne/Orange Cnty

11h 45m

1 stop

BOG10:30 pmBogotá El Dorado

Oct 3

BOG12:25 amBogotá El Dorado

11h 20m

1 stop

SNA9:45 amSanta Ana J. Wayne/Orange Cnty

$710

American Airlines

Sep 27

SNA7:30 pmSanta Ana J. Wayne/Orange Cnty

15h 35m

2 stops

BOG1:05 pmBogotá El Dorado

Oct 3

BOG12:25 amBogotá El Dorado

11h 20m

1 stop

SNA9:45 amSanta Ana J. Wayne/Orange Cnty

$715

United Airlines flights from Santa Ana, California to South America

Our best United Airlines deals on Santa Ana, California to South America flight tickets

United Airlines

Nov 3

SNA6:36 pmSanta Ana J. Wayne/Orange Cnty

24h 59m

2 stops

BOG10:35 pmBogotá El Dorado

Nov 21

BOG8:15 amBogotá El Dorado

27h 31m

2 stops

SNA8:46 amSanta Ana J. Wayne/Orange Cnty

$593

United Airlines

Nov 14

SNA8:05 amSanta Ana J. Wayne/Orange Cnty

13h 25m

1 stop

UIO12:30 amQuito Mariscal Sucr

Nov 23

UIO1:35 amQuito Mariscal Sucr

15h 16m

1 stop

SNA1:51 pmSanta Ana J. Wayne/Orange Cnty

$633

United Airlines

Nov 16

SNA4:05 pmSanta Ana J. Wayne/Orange Cnty

29h 25m

2 stops

UIO12:30 amQuito Mariscal Sucr

Nov 23

UIO1:35 amQuito Mariscal Sucr

15h 16m

1 stop

SNA1:51 pmSanta Ana J. Wayne/Orange Cnty

$638

momondo Fare Finder

Use the filters below to find and compare flights from Santa Ana, California to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Quickest round-trip

Santa AnaBogotá

SNA Santa Ana J. Wayne/Orange Cnty - BOG Bogotá El Dorado

SNABOG

Santa Ana J. Wayne/Orange Cnty

Tue 11/3

8:00 am-11:30 pm

1 stop12h 30m

Bogotá El Dorado

Sat 11/21

11:55 pm-8:28 am

1 stop11h 33m

$588

Santa AnaBogotá

SNA Santa Ana J. Wayne/Orange Cnty - BOG Bogotá El Dorado

SNABOG

Santa Ana J. Wayne/Orange Cnty

Tue 11/3

6:45 am-11:30 pm

1 stop13h 45m

Bogotá El Dorado

Sat 11/21

11:55 pm-8:28 am

1 stop11h 33m

$588

Santa AnaBogotá

SNA Santa Ana J. Wayne/Orange Cnty - BOG Bogotá El Dorado

SNABOG

Santa Ana J. Wayne/Orange Cnty

Tue 11/3

6:36 pm-10:35 pm

2 stops24h 59m

Bogotá El Dorado

Sat 11/21

8:15 am-8:46 am

2 stops27h 31m

$593

Santa AnaBogotá

SNA Santa Ana J. Wayne/Orange Cnty - BOG Bogotá El Dorado

SNABOG

Santa Ana J. Wayne/Orange Cnty

Tue 11/3

6:45 am-11:30 pm

1 stop13h 45m

Bogotá El Dorado

Sat 11/21

11:55 pm-3:42 pm

2 stops18h 47m

$593

Santa AnaQuito

SNA Santa Ana J. Wayne/Orange Cnty - UIO Quito Mariscal Sucr

SNAUIO

Santa Ana J. Wayne/Orange Cnty

Sat 11/14

8:05 am-12:30 am

1 stop13h 25m

Quito Mariscal Sucr

Mon 11/23

1:35 am-1:51 pm

1 stop15h 16m

$633

Santa AnaQuito

SNA Santa Ana J. Wayne/Orange Cnty - UIO Quito Mariscal Sucr

SNAUIO

Santa Ana J. Wayne/Orange Cnty

Tue 11/17

12:08 pm-12:30 am

1 stop9h 22m

Quito Mariscal Sucr

Mon 11/23

1:35 am-1:51 pm

1 stop15h 16m

$633

Santa AnaMedellín

SNA Santa Ana J. Wayne/Orange Cnty - MDE Medellín Jose Maria Cordova Intl

SNAMDE

Santa Ana J. Wayne/Orange Cnty

Mon 11/23

7:50 pm-1:10 pm

2 stops14h 20m

Medellín Jose Maria Cordova Intl

Mon 12/14

2:10 pm-8:42 am

2 stops21h 32m

$648

Santa AnaMedellín

SNA Santa Ana J. Wayne/Orange Cnty - MDE Medellín Jose Maria Cordova Intl

SNAMDE

Santa Ana J. Wayne/Orange Cnty

Tue 11/17

7:59 pm-1:10 pm

2 stops14h 11m

Medellín Jose Maria Cordova Intl

Thu 12/10

2:10 pm-8:42 am

2 stops21h 32m

$648

Santa AnaCartagena

SNA Santa Ana J. Wayne/Orange Cnty - CTG Cartagena Rafael Nunez

SNACTG

Santa Ana J. Wayne/Orange Cnty

Sun 10/18

11:38 am-11:35 pm

2 stops33h 57m

Cartagena Rafael Nunez

Thu 10/29

2:30 pm-12:44 pm

1 stop24h 14m

$781

Santa AnaCartagena

SNA Santa Ana J. Wayne/Orange Cnty - CTG Cartagena Rafael Nunez

SNACTG

Santa Ana J. Wayne/Orange Cnty

Sat 1/30

12:20 pm-2:10 pm

1 stop22h 50m

Cartagena Rafael Nunez

Sat 2/6

3:25 pm-12:56 pm

1 stop24h 31m

$808

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Santa Ana, California to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South America?

In general, August is the cheapest month to fly from Santa Ana, California to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $0. If you aren’t able to travel during the month of August, then book flights to South America from Santa Ana, California during April instead. Flights to South America in April, while not as cheap as those in August, still average around $0.

Can stopping save me money on Santa Ana, California to South America flights?

You could potentially save up to 50% on your flight if you consider stops on a Santa Ana, California to South America flight.

Cheap Santa Ana, California to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana, California to South America

Best Price Found	$275
Fastest flight time	10h 30m
Direct flights	None

The best one-way flight to South America from Santa Ana, California in the past 72 hours is $275. The best round-trip flight deal from Santa Ana, California to South America found on momondo in the last 72 hours is $588.

The fastest flight from Santa Ana, California to South America takes 10h 30m

There are no direct flights from Santa Ana, California to South America. There are no popular flight routes from Santa Ana, California to South America.

Search flight deals

Frequently asked questions about flying from Santa Ana, California to South America

When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to South America?
Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to South America are refreshed on a daily basis.
How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to South America?
The number of operators available for flights from Santa Ana J. Wayne/Orange Cnty Airport to South America is 3 as of September 2026.
How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to South America?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santa Ana J. Wayne/Orange Cnty Airport to South America.
What documentation or ID do you need to fly to South America?
The necessary travel and health documents for your South America trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Santa Ana, California to South America

Compare and see reviews for airlines that fly from Santa Ana, California to South America with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $502	Free Cancellation	Rating 7.1 12,023 reviews	Search American Airlines flights
Delta	PriceFrom $903	Free Cancellation	Rating 7.8 8,538 reviews	Search Delta flights
United Airlines	PriceFrom $1,025	Free Cancellation	Rating 7.4 10,157 reviews	Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to South America?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Santa Ana to South America. momondo saves you time and could save you money on your trip.

Can I find flights from Santa Ana to South America with flexible booking policies on momondo?

Yes. All flights to South America from Santa Ana on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Santa Ana to South America?

Once you have performed a search for Santa Ana to South America flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Santa Ana to South America right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Santa Ana to South America flights. All you need is a valid email address and we will do the rest; it is that quick and easy.