What airlines fly to South America?

LATAM Airlines, Copa Airlines and Avianca are the top three most popular airlines that fly to South America from Santa Ana, California according to our data. LATAM Airlines is the first choice among our users, with 46% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 10 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Santa Ana J. Wayne/Orange Cnty to South America?

United Airlines, Delta, and Copa Airlines are the most popular carriers operating from Santa Ana J. Wayne/Orange Cnty to South America

When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to South America?

Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to South America are refreshed on a daily basis.

How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to South America?

The number of operators available for flights from Santa Ana J. Wayne/Orange Cnty Airport to South America is 2 as of September 2026.

How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to South America?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santa Ana J. Wayne/Orange Cnty Airport to South America.

What documentation or ID do you need to fly to South America?

The necessary travel and health documents for your South America trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$313 Cheap Flights from Santa Ana, California to South America in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Santa Ana, California to South America

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

8:05 am - 11:32 pmSNA Santa Ana J. Wayne/Orange Cnty-CLO Cali Alfonso B. Aragon Intl

12h 27m2 stops Houston George Bush Intcntl Panama City Tocumen Intl

12:05 pm - 8:45 pmCLO Cali Alfonso B. Aragon Intl-SNA Santa Ana J. Wayne/Orange Cnty

35h 40m3 stops Panama City Tocumen Intl Houston George Bush Intcntl San Francisco

$614United Airlines

Sat, Nov 14 - Sun, Nov 22

2:59 pm - 10:35 pmSNA Santa Ana J. Wayne/Orange Cnty-BOG Bogotá El Dorado

28h 36m1 stop Houston George Bush Intcntl

8:15 am - 6:44 pmBOG Bogotá El Dorado-SNA Santa Ana J. Wayne/Orange Cnty

37h 29m2 stops Houston George Bush Intcntl San Francisco

$626United Airlines

Fri, Nov 6 - Sun, Nov 15

8:00 pm - 5:10 amSNA Santa Ana J. Wayne/Orange Cnty-BOG Bogotá El Dorado

30h 10m2 stops San Francisco Houston George Bush Intcntl

8:15 am - 8:45 pmBOG Bogotá El Dorado-SNA Santa Ana J. Wayne/Orange Cnty

39h 30m2 stops Houston George Bush Intcntl San Francisco

$626United Airlines

Fri, Nov 6 - Sun, Nov 15

8:05 am - 10:35 pmSNA Santa Ana J. Wayne/Orange Cnty-BOG Bogotá El Dorado

11h 30m1 stop Houston George Bush Intcntl

8:15 am - 1:51 pmBOG Bogotá El Dorado-SNA Santa Ana J. Wayne/Orange Cnty

32h 36m1 stop Houston George Bush Intcntl

$626United Airlines

Fri, Nov 6 - Sun, Nov 15

6:37 pm - 10:30 pmSNA Santa Ana J. Wayne/Orange Cnty-BOG Bogotá El Dorado

25h 53m1 stop Dallas/Fort Worth

11:55 pm - 8:22 amBOG Bogotá El Dorado-SNA Santa Ana J. Wayne/Orange Cnty

11h 27m1 stop Dallas/Fort Worth

$653American Airlines

Sat, Oct 17 - Tue, Nov 17

4:34 pm - 10:30 pmSNA Santa Ana J. Wayne/Orange Cnty-BOG Bogotá El Dorado

27h 56m1 stop Dallas/Fort Worth

11:55 pm - 11:50 amBOG Bogotá El Dorado-SNA Santa Ana J. Wayne/Orange Cnty

14h 55m2 stops Dallas/Fort Worth Phoenix Sky Harbor Intl

$657American Airlines

Sat, Oct 17 - Tue, Nov 17

1:23 pm - 1:35 pmSNA Santa Ana J. Wayne/Orange Cnty-CTG Cartagena Rafael Nunez

21h 12m2 stops Phoenix Sky Harbor Intl Miami

4:37 pm - 11:03 amCTG Cartagena Rafael Nunez-SNA Santa Ana J. Wayne/Orange Cnty

21h 26m2 stops Miami Dallas/Fort Worth

$702American Airlines

Wed, Nov 4 - Wed, Nov 11

3:42 pm - 1:10 pmSNA Santa Ana J. Wayne/Orange Cnty-MDE Medellín Jose Maria Cordova Intl

18h 28m2 stops San Francisco San Salvador El Salvador Intl

2:10 pm - 8:41 amMDE Medellín Jose Maria Cordova Intl-SNA Santa Ana J. Wayne/Orange Cnty

21h 31m2 stops San Salvador El Salvador Intl San Francisco

$717Multiple Airlines

Mon, Nov 9 - Fri, Nov 13

7:31 pm - 1:10 pmSNA Santa Ana J. Wayne/Orange Cnty-MDE Medellín Jose Maria Cordova Intl

15h 39m2 stops San Francisco San Salvador El Salvador Intl

2:10 pm - 8:38 amMDE Medellín Jose Maria Cordova Intl-SNA Santa Ana J. Wayne/Orange Cnty

20h 28m2 stops San Salvador El Salvador Intl San Francisco

$720Multiple Airlines

Mon, Oct 19 - Mon, Oct 26

2:10 pm - 1:10 pmSNA Santa Ana J. Wayne/Orange Cnty-MDE Medellín Jose Maria Cordova Intl

20h 00m2 stops San Francisco San Salvador El Salvador Intl

2:10 pm - 8:50 amMDE Medellín Jose Maria Cordova Intl-SNA Santa Ana J. Wayne/Orange Cnty

21h 40m2 stops San Salvador El Salvador Intl San Francisco

$725Multiple Airlines

Tue, Jan 19 - Tue, Jan 26

Cheap last minute flights

Enter your travel dates to find the best prices.

3:14 pm - 4:54 amSNA Santa Ana J. Wayne/Orange Cnty-BOG Bogotá El Dorado

11h 40m1 stop Houston George Bush Intcntl

12:14 am - 2:03 pmBOG Bogotá El Dorado-SNA Santa Ana J. Wayne/Orange Cnty

15h 49m1 stop Houston George Bush Intcntl

$808Azul

Fri, Sep 25 - Sun, Sep 27

8:13 am - 7:20 pmSNA Santa Ana J. Wayne/Orange Cnty-BOG Bogotá El Dorado

9h 07m1 stop Houston George Bush Intcntl

8:30 am - 9:51 pmBOG Bogotá El Dorado-SNA Santa Ana J. Wayne/Orange Cnty

15h 21m1 stop Houston George Bush Intcntl

$818Multiple Airlines

Wed, Sep 23 - Fri, Sep 25

3:14 pm - 4:54 amSNA Santa Ana J. Wayne/Orange Cnty-BOG Bogotá El Dorado

11h 40m1 stop Houston George Bush Intcntl

8:30 am - 9:51 pmBOG Bogotá El Dorado-SNA Santa Ana J. Wayne/Orange Cnty

15h 21m1 stop Houston George Bush Intcntl

$818Azul

Thu, Sep 24 - Sat, Sep 26

3:14 pm - 4:54 amSNA Santa Ana J. Wayne/Orange Cnty-BOG Bogotá El Dorado

11h 40m1 stop Houston George Bush Intcntl

8:30 am - 9:51 pmBOG Bogotá El Dorado-SNA Santa Ana J. Wayne/Orange Cnty

15h 21m1 stop Houston George Bush Intcntl

$819Azul

Thu, Sep 24 - Sat, Sep 26

8:10 am - 7:20 pmSNA Santa Ana J. Wayne/Orange Cnty-BOG Bogotá El Dorado

9h 10m1 stop Houston George Bush Intcntl

8:30 am - 8:51 pmBOG Bogotá El Dorado-SNA Santa Ana J. Wayne/Orange Cnty

14h 21m2 stops Houston George Bush Intcntl San Francisco

$825Azul

Thu, Sep 24 - Sat, Sep 26

9:12 am - 10:30 pmSNA Santa Ana J. Wayne/Orange Cnty-BOG Bogotá El Dorado

11h 18m1 stop Dallas/Fort Worth

11:55 pm - 11:00 amBOG Bogotá El Dorado-SNA Santa Ana J. Wayne/Orange Cnty

13h 05m1 stop Dallas/Fort Worth

$839GOL

Mon, Sep 28 - Tue, Oct 27

3:14 pm - 4:54 amSNA Santa Ana J. Wayne/Orange Cnty-BOG Bogotá El Dorado

11h 40m1 stop Houston George Bush Intcntl

12:14 am - 2:03 pmBOG Bogotá El Dorado-SNA Santa Ana J. Wayne/Orange Cnty

15h 49m1 stop Houston George Bush Intcntl

$866Azul

Fri, Sep 25 - Sun, Sep 27

8:10 am - 7:20 pmSNA Santa Ana J. Wayne/Orange Cnty-BOG Bogotá El Dorado

9h 10m1 stop Houston George Bush Intcntl

12:14 am - 11:02 amBOG Bogotá El Dorado-SNA Santa Ana J. Wayne/Orange Cnty

12h 48m1 stop Houston George Bush Intcntl

$881Azul

Fri, Sep 25 - Sat, Sep 26

6:45 am - 9:30 amSNA Santa Ana J. Wayne/Orange Cnty-GRU Sao Paulo Guarulhos Intl

22h 45m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

9:45 pm - 8:14 pmGRU Sao Paulo Guarulhos Intl-SNA Santa Ana J. Wayne/Orange Cnty

27h 29m1 stop Newark

$1,403United Airlines

Fri, Sep 25 - Fri, Nov 20

9:42 am - 9:35 amSNA Santa Ana J. Wayne/Orange Cnty-GRU Sao Paulo Guarulhos Intl

19h 53m2 stops San Francisco Chicago O'Hare Intl

9:30 pm - 1:14 pmGRU Sao Paulo Guarulhos Intl-SNA Santa Ana J. Wayne/Orange Cnty

20h 44m2 stops Chicago O'Hare Intl Denver Intl

$1,407United Airlines

Fri, Sep 25 - Fri, Nov 20

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Avianca flights from Santa Ana, California to South America

Our best Avianca deals on Santa Ana, California to South America flight tickets

Avianca

Oct 21

SNA3:14 pmSanta Ana J. Wayne/Orange Cnty

11h 40m

1 stop

BOG4:54 amBogotá El Dorado

Oct 27

BOG8:15 amBogotá El Dorado

15h 35m

1 stop

SNA9:50 pmSanta Ana J. Wayne/Orange Cnty

$724

Avianca

Mar 4

SNA8:00 amSanta Ana J. Wayne/Orange Cnty

19h 50m

1 stop

SCL8:50 amSantiago Arturo Merino Benitez

Mar 11

SCL10:45 pmSantiago Arturo Merino Benitez

17h 32m

1 stop

SNA11:17 amSanta Ana J. Wayne/Orange Cnty

$1,044

Avianca

Sep 28

SNA8:10 amSanta Ana J. Wayne/Orange Cnty

12h 50m

1 stop

LIM11:00 pmLima J Chavez Intl

Oct 25

LIM12:50 amLima J Chavez Intl

12h 21m

1 stop

SNA11:11 amSanta Ana J. Wayne/Orange Cnty

$1,782

GOL flights from Santa Ana, California to South America

Our best GOL deals on Santa Ana, California to South America flight tickets

GOL

Feb 26

SNA10:40 amSanta Ana J. Wayne/Orange Cnty

9h 21m

1 stop

BOG11:01 pmBogotá El Dorado

Mar 4

BOG12:01 amBogotá El Dorado

11h 28m

1 stop

SNA8:29 amSanta Ana J. Wayne/Orange Cnty

$769

GOL

Nov 9

SNA10:45 amSanta Ana J. Wayne/Orange Cnty

9h 45m

1 stop

BOG11:30 pmBogotá El Dorado

Nov 16

BOG11:55 pmBogotá El Dorado

15h 40m

1 stop

SNA12:35 pmSanta Ana J. Wayne/Orange Cnty

$771

GOL

Oct 31

SNA12:01 pmSanta Ana J. Wayne/Orange Cnty

9h 29m

1 stop

BOG11:30 pmBogotá El Dorado

Nov 20

BOG11:55 pmBogotá El Dorado

11h 33m

1 stop

SNA8:28 amSanta Ana J. Wayne/Orange Cnty

$783

momondo Fare Finder

Use the filters below to find and compare flights from Santa Ana, California to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santa AnaCali

SNA Santa Ana J. Wayne/Orange Cnty - CLO Cali Alfonso B. Aragon Intl

SNACLO

Santa Ana J. Wayne/Orange Cnty

Sat 11/14

8:05 am-11:32 pm

2 stops12h 27m

Cali Alfonso B. Aragon Intl

Sun 11/22

12:05 pm-8:45 pm

3 stops35h 40m

$614

Santa AnaBogotá

SNA Santa Ana J. Wayne/Orange Cnty - BOG Bogotá El Dorado

SNABOG

Santa Ana J. Wayne/Orange Cnty

Fri 11/6

2:59 pm-10:35 pm

1 stop28h 36m

Bogotá El Dorado

Sun 11/15

8:15 am-6:44 pm

2 stops37h 29m

$626

Santa AnaBogotá

SNA Santa Ana J. Wayne/Orange Cnty - BOG Bogotá El Dorado

SNABOG

Santa Ana J. Wayne/Orange Cnty

Fri 11/6

8:00 pm-5:10 am

2 stops30h 10m

Bogotá El Dorado

Sun 11/15

8:15 am-8:45 pm

2 stops39h 30m

$626

Santa AnaBogotá

SNA Santa Ana J. Wayne/Orange Cnty - BOG Bogotá El Dorado

SNABOG

Santa Ana J. Wayne/Orange Cnty

Fri 11/6

8:05 am-10:35 pm

1 stop11h 30m

Bogotá El Dorado

Sun 11/15

8:15 am-1:51 pm

1 stop32h 36m

$626

Santa AnaBogotá

SNA Santa Ana J. Wayne/Orange Cnty - BOG Bogotá El Dorado

SNABOG

Santa Ana J. Wayne/Orange Cnty

Sat 10/17

6:37 pm-10:30 pm

1 stop25h 53m

Bogotá El Dorado

Tue 11/17

11:55 pm-8:22 am

1 stop11h 27m

$653

Santa AnaBogotá

SNA Santa Ana J. Wayne/Orange Cnty - BOG Bogotá El Dorado

SNABOG

Santa Ana J. Wayne/Orange Cnty

Sat 10/17

4:34 pm-10:30 pm

1 stop27h 56m

Bogotá El Dorado

Tue 11/17

11:55 pm-11:50 am

2 stops14h 55m

$657

Santa AnaCartagena

SNA Santa Ana J. Wayne/Orange Cnty - CTG Cartagena Rafael Nunez

SNACTG

Santa Ana J. Wayne/Orange Cnty

Wed 11/4

1:23 pm-1:35 pm

2 stops21h 12m

Cartagena Rafael Nunez

Wed 11/11

4:37 pm-11:03 am

2 stops21h 26m

$702

Santa AnaMedellín

SNA Santa Ana J. Wayne/Orange Cnty - MDE Medellín Jose Maria Cordova Intl

SNAMDE

Santa Ana J. Wayne/Orange Cnty

Mon 11/9

3:42 pm-1:10 pm

2 stops18h 28m

Medellín Jose Maria Cordova Intl

Fri 11/13

2:10 pm-8:41 am

2 stops21h 31m

$717

Quickest round-trip

Santa AnaMedellín

SNA Santa Ana J. Wayne/Orange Cnty - MDE Medellín Jose Maria Cordova Intl

SNAMDE

Santa Ana J. Wayne/Orange Cnty

Mon 10/19

7:31 pm-1:10 pm

2 stops15h 39m

Medellín Jose Maria Cordova Intl

Mon 10/26

2:10 pm-8:38 am

2 stops20h 28m

$720

Santa AnaMedellín

SNA Santa Ana J. Wayne/Orange Cnty - MDE Medellín Jose Maria Cordova Intl

SNAMDE

Santa Ana J. Wayne/Orange Cnty

Tue 1/19

2:10 pm-1:10 pm

2 stops20h 00m

Medellín Jose Maria Cordova Intl

Tue 1/26

2:10 pm-8:50 am

2 stops21h 40m

$725

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Santa Ana, California to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South America?

In general, August is the cheapest month to fly from Santa Ana, California to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $0. If you aren’t able to travel during the month of August, then book flights to South America from Santa Ana, California during April instead. Flights to South America in April, while not as cheap as those in August, still average around $0.

Can stopping save me money on Santa Ana, California to South America flights?

You could potentially save up to 17% on your flight if you consider stops on a Santa Ana, California to South America flight.

Cheap Santa Ana, California to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana, California to South America

Best Price Found	$313
Fastest flight time	9h 29m
Direct flights	None

The best one-way flight to South America from Santa Ana, California in the past 72 hours is $313. The best round-trip flight deal from Santa Ana, California to South America found on momondo in the last 72 hours is $614.

The fastest flight from Santa Ana, California to South America takes 9h 29m

There are no direct flights from Santa Ana, California to South America. There are no popular flight routes from Santa Ana, California to South America.

Search flight deals

Frequently asked questions about flying from Santa Ana, California to South America

When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to South America?
Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to South America are refreshed on a daily basis.
How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to South America?
The number of operators available for flights from Santa Ana J. Wayne/Orange Cnty Airport to South America is 2 as of September 2026.
How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to South America?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santa Ana J. Wayne/Orange Cnty Airport to South America.
What documentation or ID do you need to fly to South America?
The necessary travel and health documents for your South America trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Santa Ana, California to South America

Compare and see reviews for airlines that fly from Santa Ana, California to South America with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $579	Free Cancellation	Rating 7.0 12,072 reviews		Search American Airlines flights
United Airlines	PriceFrom $1,025	Free Cancellation	Rating 7.4 10,220 reviews		Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to South America?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Santa Ana to South America. momondo saves you time and could save you money on your trip.

Can I find flights from Santa Ana to South America with flexible booking policies on momondo?

Yes. All flights to South America from Santa Ana on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Santa Ana to South America?

Once you have performed a search for Santa Ana to South America flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Santa Ana to South America right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Santa Ana to South America flights. All you need is a valid email address and we will do the rest; it is that quick and easy.