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Cheap flights from Santa Ana, California to Key West from $389

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Ana, California to Key West departing on 11/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Santa Ana, California to Key West

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
7:45 am - 6:45 pm
SNA
-
EYW
8h 00m
1 stop
American Airlines Logo
2:26 pm - 7:10 pm
EYW
-
SNA
7h 44m
1 stop
$389American Airlines
Sun, Nov 1 - Sat, Nov 7
Delta Logo
6:45 am - 7:57 pm
SNA
-
EYW
10h 12m
1 stop
Delta Logo
7:40 am - 12:33 pm
EYW
-
SNA
7h 53m
1 stop
$444Delta
Sat, Sep 5 - Wed, Sep 9
Breeze Airways Logo
1:10 pm - 11:25 am
SNA
-
EYW
19h 15m
1 stop
Breeze Airways Logo
11:46 am - 12:11 pm
EYW
-
SNA
51h 25m
2 stops
$470Breeze Airways
Sat, Aug 8 - Wed, Aug 12
American Airlines Logo
6:45 am - 4:55 pm
SNA
-
EYW
7h 10m
1 stop
American Airlines Logo
2:26 pm - 7:10 pm
EYW
-
SNA
7h 44m
1 stop
$472American Airlines
Sat, Nov 7 - Wed, Nov 11
American Airlines Logo
6:45 am - 4:55 pm
SNA
-
EYW
7h 10m
1 stop
American Airlines Logo
6:35 pm - 9:04 am
EYW
-
SNA
17h 29m
2 stops
$496American Airlines
Sat, Nov 7 - Wed, Nov 11
Delta Logo
7:00 am - 7:57 pm
SNA
-
EYW
9h 57m
2 stops
Delta Logo
7:40 am - 12:33 pm
EYW
-
SNA
7h 53m
1 stop
$504Delta
Sat, Sep 5 - Wed, Sep 9
Delta Logo
6:45 am - 7:57 pm
SNA
-
EYW
10h 12m
1 stop
Delta Logo
1:59 pm - 6:37 pm
EYW
-
SNA
7h 38m
1 stop
$527Delta
Sat, Aug 22 - Wed, Aug 26
American Airlines Logo
7:45 am - 6:45 pm
SNA
-
EYW
8h 00m
1 stop
American Airlines Logo
10:18 am - 5:42 pm
EYW
-
SNA
10h 24m
2 stops
$536American Airlines
Sun, Nov 1 - Sat, Nov 7
United Airlines Logo
6:30 pm - 3:29 pm
SNA
-
EYW
17h 59m
2 stops
United Airlines Logo
2:50 pm - 10:44 am
EYW
-
SNA
22h 54m
1 stop
$810United Airlines
Tue, Oct 27 - Sat, Oct 31
United Airlines Logo
11:10 am - 3:29 pm
SNA
-
EYW
25h 19m
2 stops
United Airlines Logo
2:50 pm - 3:59 pm
EYW
-
SNA
28h 09m
2 stops
$813United Airlines
Tue, Oct 27 - Sat, Oct 31

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American Airlines flights from Santa Ana, California to Key West

Our best American Airlines deals on Santa Ana, California to Key West flight tickets
American Airlines
Nov 1
SNA7:45 amSanta Ana J. Wayne/Orange Cnty
8h 00m
1 stop
EYW6:45 pmKey West
Nov 7
EYW2:26 pmKey West
7h 44m
1 stop
SNA7:10 pmSanta Ana J. Wayne/Orange Cnty
$389
American Airlines
Nov 7
SNA6:45 amSanta Ana J. Wayne/Orange Cnty
7h 10m
1 stop
EYW4:55 pmKey West
Nov 11
EYW2:26 pmKey West
7h 44m
1 stop
SNA7:10 pmSanta Ana J. Wayne/Orange Cnty
$472
American Airlines
Nov 7
SNA6:45 amSanta Ana J. Wayne/Orange Cnty
7h 10m
1 stop
EYW4:55 pmKey West
Nov 11
EYW6:35 pmKey West
17h 29m
2 stops
SNA9:04 amSanta Ana J. Wayne/Orange Cnty
$496

Delta flights from Santa Ana, California to Key West

Our best Delta deals on Santa Ana, California to Key West flight tickets
Delta
Sep 5
SNA6:45 amSanta Ana J. Wayne/Orange Cnty
10h 12m
1 stop
EYW7:57 pmKey West
Sep 9
EYW7:40 amKey West
7h 53m
1 stop
SNA12:33 pmSanta Ana J. Wayne/Orange Cnty
$444
Delta
Sep 5
SNA7:00 amSanta Ana J. Wayne/Orange Cnty
9h 57m
2 stops
EYW7:57 pmKey West
Sep 9
EYW7:40 amKey West
7h 53m
1 stop
SNA12:33 pmSanta Ana J. Wayne/Orange Cnty
$504
Delta
Aug 22
SNA6:45 amSanta Ana J. Wayne/Orange Cnty
10h 12m
1 stop
EYW7:57 pmKey West
Aug 26
EYW1:59 pmKey West
7h 38m
1 stop
SNA6:37 pmSanta Ana J. Wayne/Orange Cnty
$527

momondo Fare Finder

 
Customize your flight search to find flights from Santa Ana, California to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 28, 2026.
Use the filters below to find and compare flights from Santa Ana, California to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Sun 11/1

7:45 am-6:45 pm

1 stop8h 00m

Key West

Sat 11/7

2:26 pm-7:10 pm

1 stop7h 44m

$389

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Sat 9/5

6:45 am-7:57 pm

1 stop10h 12m

Key West

Wed 9/9

7:40 am-12:33 pm

1 stop7h 53m

$444

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Sat 8/8

1:10 pm-11:25 am

1 stop19h 15m

Key West

Wed 8/12

11:46 am-12:11 pm

2 stops51h 25m

$470
Quickest round-trip

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Sat 11/7

6:45 am-4:55 pm

1 stop7h 10m

Key West

Wed 11/11

2:26 pm-7:10 pm

1 stop7h 44m

$472

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Sat 11/7

6:45 am-4:55 pm

1 stop7h 10m

Key West

Wed 11/11

6:35 pm-9:04 am

2 stops17h 29m

$496

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Sat 9/5

7:00 am-7:57 pm

2 stops9h 57m

Key West

Wed 9/9

7:40 am-12:33 pm

1 stop7h 53m

$504

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Sat 8/22

6:45 am-7:57 pm

1 stop10h 12m

Key West

Wed 8/26

1:59 pm-6:37 pm

1 stop7h 38m

$527

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Sun 11/1

7:45 am-6:45 pm

1 stop8h 00m

Key West

Sat 11/7

10:18 am-5:42 pm

2 stops10h 24m

$536

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Tue 10/27

6:30 pm-3:29 pm

2 stops17h 59m

Key West

Sat 10/31

2:50 pm-10:44 am

1 stop22h 54m

$810

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Tue 10/27

11:10 am-3:29 pm

2 stops25h 19m

Key West

Sat 10/31

2:50 pm-3:59 pm

2 stops28h 09m

$813

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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See travel insights to Key West from

How to get the cheapest flight ticket from Santa Ana, California to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Key West?

In general, August is the cheapest month to fly from Santa Ana, California to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $0. If you are unable to visit Key West during the month of August, then departing from Santa Ana, California during the month May is also very affordable. Most momondo users find prices during this month for around $0.

When to book flights from Santa Ana, California to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from Santa Ana, California to Key West according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santa Ana, California to Key West (SNA to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana, California to Key West

Fastest flight time

9h 58m

Direct flights

None
The fastest flight from Santa Ana, California to Key West takes 9h 58m
There are no direct flights from Santa Ana, California to Key West. There are no popular flight routes from Santa Ana, California to Key West.
Search flight deals

Frequently asked questions about flying from Santa Ana, California to Key West

  • How far is Santa Ana J. Wayne/Orange Cnty to Key West by plane?

    Key West is 2252.7 mi away from Santa Ana J. Wayne/Orange Cnty. By plane, this route typically takes 9h 58m.

  • When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Key West Airport?

    Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Key West Airport are updated daily.

  • How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to Key West Airport?

  • How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Key West Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santa Ana J. Wayne/Orange Cnty Airport to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The travel and health documents you'll need for your trip to Key West Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Key West Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Santa Ana, California to Key West?

Best airlines flying from Santa Ana, California to Key West

Compare and see reviews for airlines that fly from Santa Ana, California to Key West with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $242Free CancellationRating
7.8
8,490 reviews
Search Delta flights
American AirlinesPriceFrom $353Free CancellationRating
7.1
11,845 reviews
Search American Airlines flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to Key West?

Finding the right flight to Key West from Santa Ana is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Key West quick and easy, saving you time and money.

Can I find flights from Santa Ana to Key West with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Santa Ana to Key West flights to just show those with flexible booking policies.

How can momondo help me find flights from Santa Ana to Key West?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Santa Ana to Key West.

I’m not ready to book a flight from Santa Ana to Key West right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Key West from Santa Ana. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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