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Cheap flights from Santa Ana, California to Key West from $200

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Ana, California to Key West departing on 4/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Santa Ana, California to Key West

Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
10:48 am - 11:30 am
SNA
-
EYW
21h 42m
2 stops
Spirit Airlines Logo
12:25 pm - 9:53 am
EYW
-
SNA
24h 28m
2 stops
$336Spirit Airlines
Tue, Mar 24 - Tue, Mar 31
Spirit Airlines Logo
10:48 am - 11:30 am
SNA
-
EYW
21h 42m
2 stops
Spirit Airlines Logo
12:25 pm - 9:53 am
EYW
-
SNA
24h 28m
2 stops
$353Spirit Airlines
Tue, Mar 24 - Thu, Apr 2
Spirit Airlines Logo
2:53 pm - 11:30 am
SNA
-
EYW
17h 37m
2 stops
Spirit Airlines Logo
12:25 pm - 1:58 pm
EYW
-
SNA
28h 33m
3 stops
$411Spirit Airlines
Tue, Mar 24 - Tue, Mar 31
American Airlines Logo
7:45 am - 10:58 pm
SNA
-
EYW
12h 13m
2 stops
American Airlines Logo
2:01 pm - 9:14 pm
EYW
-
SNA
10h 13m
1 stop
$434American Airlines
Wed, Apr 8 - Wed, Apr 15
Spirit Airlines Logo
6:45 am - 11:30 am
SNA
-
EYW
25h 45m
3 stops
Spirit Airlines Logo
12:25 pm - 9:53 am
EYW
-
SNA
24h 28m
2 stops
$460Spirit Airlines
Tue, Mar 24 - Thu, Apr 2
Spirit Airlines Logo
2:53 pm - 11:30 am
SNA
-
EYW
17h 37m
2 stops
Spirit Airlines Logo
2:35 pm - 1:58 pm
EYW
-
SNA
26h 23m
3 stops
$465Spirit Airlines
Tue, Mar 24 - Mon, Mar 30
Spirit Airlines Logo
10:48 am - 11:30 am
SNA
-
EYW
21h 42m
2 stops
Spirit Airlines Logo
12:25 pm - 9:53 am
EYW
-
SNA
24h 28m
3 stops
$479Spirit Airlines
Tue, Mar 24 - Sun, Mar 29
American Airlines Logo
9:30 am - 10:58 pm
SNA
-
EYW
10h 28m
2 stops
American Airlines Logo
2:29 pm - 8:56 pm
EYW
-
SNA
9h 27m
1 stop
$481American Airlines
Sat, May 9 - Sat, May 16
American Airlines Logo
8:17 am - 10:58 pm
SNA
-
EYW
11h 41m
2 stops
American Airlines Logo
2:29 pm - 10:05 pm
EYW
-
SNA
10h 36m
2 stops
$486American Airlines
Sat, May 9 - Sat, May 16
American Airlines Logo
7:45 am - 10:58 pm
SNA
-
EYW
12h 13m
2 stops
American Airlines Logo
11:24 am - 8:50 pm
EYW
-
SNA
12h 26m
2 stops
$497American Airlines
Wed, Apr 8 - Wed, Apr 15

Spirit Airlines flights from Santa Ana, California to Key West

Our best Spirit Airlines deals on Santa Ana, California to Key West flight tickets
Spirit Airlines
Mar 24
SNA10:48 amSanta Ana J. Wayne/Orange Cnty
21h 42m
2 stops
EYW11:30 amKey West
Mar 31
EYW12:25 pmKey West
24h 28m
2 stops
SNA9:53 amSanta Ana J. Wayne/Orange Cnty
$336
Spirit Airlines
Mar 24
SNA10:48 amSanta Ana J. Wayne/Orange Cnty
21h 42m
2 stops
EYW11:30 amKey West
Apr 2
EYW12:25 pmKey West
24h 28m
2 stops
SNA9:53 amSanta Ana J. Wayne/Orange Cnty
$353
Spirit Airlines
Mar 24
SNA2:53 pmSanta Ana J. Wayne/Orange Cnty
17h 37m
2 stops
EYW11:30 amKey West
Mar 31
EYW12:25 pmKey West
28h 33m
3 stops
SNA1:58 pmSanta Ana J. Wayne/Orange Cnty
$411

American Airlines flights from Santa Ana, California to Key West

Our best American Airlines deals on Santa Ana, California to Key West flight tickets
American Airlines
Apr 8
SNA7:45 amSanta Ana J. Wayne/Orange Cnty
12h 13m
2 stops
EYW10:58 pmKey West
Apr 15
EYW2:01 pmKey West
10h 13m
1 stop
SNA9:14 pmSanta Ana J. Wayne/Orange Cnty
$434
American Airlines
May 9
SNA9:30 amSanta Ana J. Wayne/Orange Cnty
10h 28m
2 stops
EYW10:58 pmKey West
May 16
EYW2:29 pmKey West
9h 27m
1 stop
SNA8:56 pmSanta Ana J. Wayne/Orange Cnty
$481
American Airlines
May 9
SNA8:17 amSanta Ana J. Wayne/Orange Cnty
11h 41m
2 stops
EYW10:58 pmKey West
May 16
EYW2:29 pmKey West
10h 36m
2 stops
SNA10:05 pmSanta Ana J. Wayne/Orange Cnty
$486

momondo Fare Finder

 
Customize your flight search to find flights from Santa Ana, California to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 3, 2026.
Use the filters below to find and compare flights from Santa Ana, California to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Tue 3/24

10:48 am-11:30 am

2 stops21h 42m

Key West

Tue 3/31

12:25 pm-9:53 am

2 stops24h 28m

$336

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Tue 3/24

10:48 am-11:30 am

2 stops21h 42m

Key West

Thu 4/2

12:25 pm-9:53 am

2 stops24h 28m

$353

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Tue 3/24

2:53 pm-11:30 am

2 stops17h 37m

Key West

Tue 3/31

12:25 pm-1:58 pm

3 stops28h 33m

$411

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Wed 4/8

7:45 am-10:58 pm

2 stops12h 13m

Key West

Wed 4/15

2:01 pm-9:14 pm

1 stop10h 13m

$434

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Tue 3/24

6:45 am-11:30 am

3 stops25h 45m

Key West

Thu 4/2

12:25 pm-9:53 am

2 stops24h 28m

$460

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Tue 3/24

2:53 pm-11:30 am

2 stops17h 37m

Key West

Mon 3/30

2:35 pm-1:58 pm

3 stops26h 23m

$465

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Tue 3/24

10:48 am-11:30 am

2 stops21h 42m

Key West

Sun 3/29

12:25 pm-9:53 am

3 stops24h 28m

$479

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Sat 5/9

9:30 am-10:58 pm

2 stops10h 28m

Key West

Sat 5/16

2:29 pm-8:56 pm

1 stop9h 27m

$481

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Sat 5/9

8:17 am-10:58 pm

2 stops11h 41m

Key West

Sat 5/16

2:29 pm-10:05 pm

2 stops10h 36m

$486

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Wed 4/8

7:45 am-10:58 pm

2 stops12h 13m

Key West

Wed 4/15

11:24 am-8:50 pm

2 stops12h 26m

$497

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Key West from

How to get the cheapest flight ticket from Santa Ana, California to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Santa Ana J. Wayne/Orange Cnty to Key West?

American Airlines is the most popular carrier operating from Santa Ana J. Wayne/Orange Cnty to Key West

When to book flights from Santa Ana, California to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from Santa Ana, California to Key West according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santa Ana, California to Key West (SNA to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana, California to Key West

Fastest flight time

9h 04m

Direct flights

None
The fastest flight from Santa Ana, California to Key West takes 9h 04m
There are no direct flights from Santa Ana, California to Key West. There are no popular flight routes from Santa Ana, California to Key West.
Search flight deals

  • How far is Santa Ana J. Wayne/Orange Cnty to Key West by plane?

    Key West is 2252.7 mi away from Santa Ana J. Wayne/Orange Cnty. By plane, this route typically takes 9h 04m.

  • When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Key West Airport?

    Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Key West Airport are updated daily.

  • How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to Key West Airport?

  • How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Key West Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santa Ana J. Wayne/Orange Cnty Airport to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The travel and health documents you'll need for your trip to Key West Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Key West Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Santa Ana, California to Key West?

Best airlines flying from Santa Ana, California to Key West

Compare and see reviews for airlines that fly from Santa Ana, California to Key West with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $353Free CancellationRating
7.1
11,375 reviews
Search American Airlines flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to Key West?

Finding the right flight to Key West from Santa Ana is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Key West quick and easy, saving you time and money.

Can I find flights from Santa Ana to Key West with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Santa Ana to Key West flights to just show those with flexible booking policies.

How can momondo help me find flights from Santa Ana to Key West?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Santa Ana to Key West.

I’m not ready to book a flight from Santa Ana to Key West right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Key West from Santa Ana. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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