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Cheap flights from Santa Ana, California to Key West from $202

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Ana, California to Key West departing on 12/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Santa Ana, California to Key West

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
6:45 am - 7:40 pmSNA-EYW
9h 55m1 stop
Delta Logo
2:45 pm - 8:04 pmEYW-SNA
8h 19m1 stop
$349Delta
Find Deal
Sat, Jan 10 - Wed, Jan 14
Delta Logo
6:45 am - 7:40 pmSNA-EYW
9h 55m1 stop
Delta Logo
12:24 pm - 8:04 pmEYW-SNA
10h 40m1 stop
$384Delta
Find Deal
Sat, Jan 10 - Wed, Jan 14
American Airlines Logo
7:50 am - 11:56 pmSNA-EYW
13h 06m2 stops
American Airlines Logo
1:16 pm - 10:01 pmEYW-SNA
11h 45m1 stop
$414American Airlines
Find Deal
Sat, Jan 10 - Wed, Jan 14
American Airlines Logo
7:50 am - 11:56 pmSNA-EYW
13h 06m2 stops
American Airlines Logo
1:33 pm - 10:01 pmEYW-SNA
11h 28m2 stops
$419American Airlines
Find Deal
Sat, Jan 10 - Wed, Jan 14
American Airlines Logo
6:45 am - 9:47 pmSNA-EYW
12h 02m2 stops
American Airlines Logo
1:33 pm - 10:01 pmEYW-SNA
11h 28m2 stops
$459American Airlines
Find Deal
Sat, Jan 10 - Wed, Jan 14
Multiple Airlines Logo
11:11 am - 1:30 pmSNA-EYW
23h 19m3 stops
Multiple Airlines Logo
10:37 pm - 7:08 pmEYW-SNA
23h 31m2 stops
$467Multiple Airlines
Find Deal
Tue, Dec 30 - Sun, Jan 4
Multiple Airlines Logo
11:11 am - 1:30 pmSNA-EYW
23h 19m2 stops
Multiple Airlines Logo
10:37 pm - 7:08 pmEYW-SNA
23h 31m2 stops
$489Multiple Airlines
Find Deal
Tue, Dec 30 - Sun, Jan 4
Spirit Airlines Logo
11:11 am - 1:30 pmSNA-EYW
23h 19m3 stops
Spirit Airlines Logo
12:20 pm - 10:16 amEYW-SNA
24h 56m3 stops
$563Spirit Airlines
Find Deal
Tue, Dec 30 - Sun, Jan 4
American Airlines Logo
7:51 am - 6:23 pmSNA-EYW
7h 32m1 stop
American Airlines Logo
3:06 pm - 8:22 pmEYW-SNA
8h 16m1 stop
$623American Airlines
Find Deal
Thu, Apr 30 - Mon, May 4
American Airlines Logo
7:51 am - 6:23 pmSNA-EYW
7h 32m1 stop
American Airlines Logo
3:06 pm - 9:47 pmEYW-SNA
9h 41m2 stops
$727American Airlines
Find Deal
Thu, Apr 30 - Mon, May 4

United Airlines flights from Santa Ana, California to Key West

Our best United Airlines deals on Santa Ana, California to Key West flight tickets
United Airlines
Apr 30
SNA2:03 pmSanta Ana J. Wayne/Orange Cnty
22h 03m
1 stop
EYW3:06 pmKey West
May 4
EYW4:05 pmKey West
32h 48m
2 stops
SNA9:53 pmSanta Ana J. Wayne/Orange Cnty
$801
Find similar
United Airlines
Apr 30
SNA2:03 pmSanta Ana J. Wayne/Orange Cnty
22h 03m
1 stop
EYW3:06 pmKey West
May 4
EYW4:05 pmKey West
31h 14m
3 stops
SNA8:19 pmSanta Ana J. Wayne/Orange Cnty
$807
Find similar
United Airlines
Apr 30
SNA7:00 pmSanta Ana J. Wayne/Orange Cnty
17h 06m
2 stops
EYW3:06 pmKey West
May 4
EYW4:05 pmKey West
31h 14m
3 stops
SNA8:19 pmSanta Ana J. Wayne/Orange Cnty
$891
Find similar

American Airlines flights from Santa Ana, California to Key West

Our best American Airlines deals on Santa Ana, California to Key West flight tickets
American Airlines
Jan 10
SNA7:50 amSanta Ana J. Wayne/Orange Cnty
13h 06m
2 stops
EYW11:56 pmKey West
Jan 14
EYW1:16 pmKey West
11h 45m
1 stop
SNA10:01 pmSanta Ana J. Wayne/Orange Cnty
$414
Find similar
American Airlines
Jan 10
SNA7:50 amSanta Ana J. Wayne/Orange Cnty
13h 06m
2 stops
EYW11:56 pmKey West
Jan 14
EYW1:33 pmKey West
11h 28m
2 stops
SNA10:01 pmSanta Ana J. Wayne/Orange Cnty
$419
Find similar
American Airlines
Jan 10
SNA6:45 amSanta Ana J. Wayne/Orange Cnty
12h 02m
2 stops
EYW9:47 pmKey West
Jan 14
EYW1:33 pmKey West
11h 28m
2 stops
SNA10:01 pmSanta Ana J. Wayne/Orange Cnty
$459
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Santa Ana, California to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 26, 2025.
Use the filters below to find and compare flights from Santa Ana, California to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Sat 1/10

6:45 am-7:40 pm

1 stop9h 55m

Key West

Wed 1/14

2:45 pm-8:04 pm

1 stop8h 19m

$349

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Sat 1/10

6:45 am-7:40 pm

1 stop9h 55m

Key West

Wed 1/14

12:24 pm-8:04 pm

1 stop10h 40m

$384

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Sat 1/10

7:50 am-11:56 pm

2 stops13h 06m

Key West

Wed 1/14

1:16 pm-10:01 pm

1 stop11h 45m

$414

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Sat 1/10

7:50 am-11:56 pm

2 stops13h 06m

Key West

Wed 1/14

1:33 pm-10:01 pm

2 stops11h 28m

$419

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Sat 1/10

6:45 am-9:47 pm

2 stops12h 02m

Key West

Wed 1/14

1:33 pm-10:01 pm

2 stops11h 28m

$459

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Tue 12/30

11:11 am-1:30 pm

3 stops23h 19m

Key West

Sun 1/4

10:37 pm-7:08 pm

2 stops23h 31m

$467

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Tue 12/30

11:11 am-1:30 pm

2 stops23h 19m

Key West

Sun 1/4

10:37 pm-7:08 pm

2 stops23h 31m

$489

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Tue 12/30

11:11 am-1:30 pm

3 stops23h 19m

Key West

Sun 1/4

12:20 pm-10:16 am

3 stops24h 56m

$563

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Thu 4/30

7:51 am-6:23 pm

1 stop7h 32m

Key West

Mon 5/4

3:06 pm-8:22 pm

1 stop8h 16m

$623

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Thu 4/30

7:51 am-6:23 pm

1 stop7h 32m

Key West

Mon 5/4

3:06 pm-9:47 pm

2 stops9h 41m

$727

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 15 resultsSorted by cheapest first
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See travel insights to Key West from

How to get the cheapest flight ticket from Santa Ana, California to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Key West?

On average, the least expensive day to fly to Key West from Santa Ana, California is on a Saturday. momondo users have found tickets for Saturday departures for as low as $447. However, this price may fluctuate depending on the airline, the season, and holidays. When flying out on a Thursday, the most expensive travel day of the week, you can expect to see flight prices from Santa Ana, California to Key West for around $597.

What is the cheapest time of day to depart on your flight to Key West?

According to our data, the cheapest time of day to fly to Key West is in the morning. momondo users have found flights departing from Santa Ana, California to Key West in the morning for as low as $496. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights to Key West are more costly in the evening, with an average ticket price of $594. Departure times in the evening fall within the peak daily travel times, which is why tickets can be more expensive.

When to book flights from Santa Ana, California to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from Santa Ana, California to Key West according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santa Ana, California to Key West (SNA to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana, California to Key West

Fastest flight time

7h 30m

Direct flights

None
The fastest flight from Santa Ana, California to Key West takes 7h 30m
There are no direct flights from Santa Ana, California to Key West. There are no popular flight routes from Santa Ana, California to Key West.
Search flight deals

  • How far is Santa Ana J. Wayne/Orange Cnty to Key West by plane?

    Key West is 2252.7 mi away from Santa Ana J. Wayne/Orange Cnty. By plane, this route typically takes 7h 30m.

  • When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Key West Airport?

    Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Key West Airport are updated daily.

  • How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to Key West Airport?

  • How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Key West Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santa Ana J. Wayne/Orange Cnty Airport to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The travel and health documents you'll need for your trip to Key West Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Key West Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Santa Ana, California to Key West?

Best airlines flying from Santa Ana, California to Key West

Compare and see reviews for airlines that fly from Santa Ana, California to Key West with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $344Free CancellationRating
7.2
11,038 reviews
Search American Airlines flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to Key West?

Finding the right flight to Key West from Santa Ana is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Key West quick and easy, saving you time and money.

Can I find flights from Santa Ana to Key West with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Santa Ana to Key West flights to just show those with flexible booking policies.

How can momondo help me find flights from Santa Ana to Key West?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Santa Ana to Key West.

I’m not ready to book a flight from Santa Ana to Key West right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Key West from Santa Ana. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your Key West trip

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