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Cheap flights from Santa Ana, California to Key West from $455

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Ana, California to Key West departing on 7/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Santa Ana, California to Key West

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:46 am - 4:54 pm
SNA
-
EYW
7h 08m
1 stop
American Airlines Logo
1:01 pm - 8:06 pm
EYW
-
SNA
10h 05m
1 stop
$455American Airlines
Fri, Jul 3 - Fri, Jul 10
Multiple Airlines Logo
1:10 pm - 11:25 am
SNA
-
EYW
19h 15m
1 stop
Multiple Airlines Logo
2:44 pm - 2:51 pm
EYW
-
SNA
27h 07m
2 stops
$493Multiple Airlines
Sat, Jul 4 - Sat, Jul 18
Delta Logo
7:05 pm - 10:50 am
SNA
-
EYW
12h 45m
2 stops
Delta Logo
7:40 am - 12:46 pm
EYW
-
SNA
8h 06m
1 stop
$531Delta
Thu, Aug 27 - Mon, Aug 31
Multiple Airlines Logo
1:10 pm - 11:25 am
SNA
-
EYW
19h 15m
1 stop
Multiple Airlines Logo
2:44 pm - 2:51 pm
EYW
-
SNA
27h 07m
2 stops
$536Multiple Airlines
Sat, Jul 4 - Sat, Jul 18
Multiple Airlines Logo
1:04 pm - 10:24 am
SNA
-
EYW
42h 20m
2 stops
Multiple Airlines Logo
3:27 pm - 12:25 pm
EYW
-
SNA
23h 58m
1 stop
$541Multiple Airlines
Fri, Jul 3 - Fri, Jul 10
Breeze Airways Logo
1:10 pm - 11:25 am
SNA
-
EYW
19h 15m
1 stop
Breeze Airways Logo
12:07 pm - 12:15 pm
EYW
-
SNA
27h 08m
1 stop
$567Breeze Airways
Sat, Jun 20 - Mon, Jun 22
Multiple Airlines Logo
3:32 pm - 12:34 pm
SNA
-
EYW
18h 02m
2 stops
Multiple Airlines Logo
12:07 pm - 12:25 pm
EYW
-
SNA
27h 18m
1 stop
$575Multiple Airlines
Mon, Jul 13 - Fri, Jul 31
American Airlines Logo
1:34 pm - 10:56 am
SNA
-
EYW
18h 22m
2 stops
American Airlines Logo
7:03 pm - 11:39 am
EYW
-
SNA
19h 36m
2 stops
$581American Airlines
Mon, Aug 31 - Tue, Sep 8
American Airlines Logo
6:45 am - 4:29 pm
SNA
-
EYW
6h 44m
1 stop
American Airlines Logo
2:39 pm - 8:03 pm
EYW
-
SNA
8h 24m
1 stop
$601American Airlines
Thu, Nov 19 - Thu, Nov 26
Multiple Airlines Logo
3:34 pm - 11:04 am
SNA
-
EYW
16h 30m
1 stop
Multiple Airlines Logo
9:16 pm - 12:34 pm
EYW
-
SNA
42h 18m
2 stops
$612Multiple Airlines
Thu, Jun 18 - Thu, Jun 25

Breeze Airways flights from Santa Ana, California to Key West

Our best Breeze Airways deals on Santa Ana, California to Key West flight tickets
Breeze Airways
Jun 20
SNA1:10 pmSanta Ana J. Wayne/Orange Cnty
19h 15m
1 stop
EYW11:25 amKey West
Jun 22
EYW12:07 pmKey West
27h 08m
1 stop
SNA12:15 pmSanta Ana J. Wayne/Orange Cnty
$567
Breeze Airways
Jun 17
SNA1:10 pmSanta Ana J. Wayne/Orange Cnty
19h 15m
1 stop
EYW11:25 amKey West
Jun 21
EYW12:05 pmKey West
27h 06m
2 stops
SNA12:11 pmSanta Ana J. Wayne/Orange Cnty
$631
Breeze Airways
Jun 20
SNA7:30 amSanta Ana J. Wayne/Orange Cnty
24h 55m
3 stops
EYW11:25 amKey West
Jun 22
EYW12:07 pmKey West
27h 08m
1 stop
SNA12:15 pmSanta Ana J. Wayne/Orange Cnty
$896

American Airlines flights from Santa Ana, California to Key West

Our best American Airlines deals on Santa Ana, California to Key West flight tickets
American Airlines
Jul 3
SNA6:46 amSanta Ana J. Wayne/Orange Cnty
7h 08m
1 stop
EYW4:54 pmKey West
Jul 10
EYW1:01 pmKey West
10h 05m
1 stop
SNA8:06 pmSanta Ana J. Wayne/Orange Cnty
$455
American Airlines
Aug 31
SNA1:34 pmSanta Ana J. Wayne/Orange Cnty
18h 22m
2 stops
EYW10:56 amKey West
Sep 8
EYW7:03 pmKey West
19h 36m
2 stops
SNA11:39 amSanta Ana J. Wayne/Orange Cnty
$581
American Airlines
Nov 19
SNA6:45 amSanta Ana J. Wayne/Orange Cnty
6h 44m
1 stop
EYW4:29 pmKey West
Nov 26
EYW2:39 pmKey West
8h 24m
1 stop
SNA8:03 pmSanta Ana J. Wayne/Orange Cnty
$601

momondo Fare Finder

 
Customize your flight search to find flights from Santa Ana, California to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 6, 2026.
Use the filters below to find and compare flights from Santa Ana, California to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Fri 7/3

6:46 am-4:54 pm

1 stop7h 08m

Key West

Fri 7/10

1:01 pm-8:06 pm

1 stop10h 05m

$455

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Sat 7/4

1:10 pm-11:25 am

1 stop19h 15m

Key West

Sat 7/18

2:44 pm-2:51 pm

2 stops27h 07m

$493

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Thu 8/27

7:05 pm-10:50 am

2 stops12h 45m

Key West

Mon 8/31

7:40 am-12:46 pm

1 stop8h 06m

$531

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Sat 7/4

1:10 pm-11:25 am

1 stop19h 15m

Key West

Sat 7/18

2:44 pm-2:51 pm

2 stops27h 07m

$536

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Fri 7/3

1:04 pm-10:24 am

2 stops42h 20m

Key West

Fri 7/10

3:27 pm-12:25 pm

1 stop23h 58m

$541

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Sat 6/20

1:10 pm-11:25 am

1 stop19h 15m

Key West

Mon 6/22

12:07 pm-12:15 pm

1 stop27h 08m

$567

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Mon 7/13

3:32 pm-12:34 pm

2 stops18h 02m

Key West

Fri 7/31

12:07 pm-12:25 pm

1 stop27h 18m

$575

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Mon 8/31

1:34 pm-10:56 am

2 stops18h 22m

Key West

Tue 9/8

7:03 pm-11:39 am

2 stops19h 36m

$581
Quickest round-trip

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Thu 11/19

6:45 am-4:29 pm

1 stop6h 44m

Key West

Thu 11/26

2:39 pm-8:03 pm

1 stop8h 24m

$601

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Thu 6/18

3:34 pm-11:04 am

1 stop16h 30m

Key West

Thu 6/25

9:16 pm-12:34 pm

2 stops42h 18m

$612

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Key West from

How to get the cheapest flight ticket from Santa Ana, California to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santa Ana, California and Key West?

What is the cheapest month to fly to Key West?

In general, May is the cheapest month to fly from Santa Ana, California to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $347. If you are unable to visit Key West during the month of May, then departing from Santa Ana, California during the month November is also very affordable. Most momondo users find prices during this month for around $348.

When to book flights from Santa Ana, California to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from Santa Ana, California to Key West according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santa Ana, California to Key West (SNA to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana, California to Key West

Fastest flight time

9h 08m

Direct flights

None
The fastest flight from Santa Ana, California to Key West takes 9h 08m
There are no direct flights from Santa Ana, California to Key West. There are no popular flight routes from Santa Ana, California to Key West.
Search flight deals

Frequently asked questions about flying from Santa Ana, California to Key West

  • How far is Santa Ana J. Wayne/Orange Cnty to Key West by plane?

    Key West is 2252.7 mi away from Santa Ana J. Wayne/Orange Cnty. By plane, this route typically takes 9h 08m.

  • When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Key West Airport?

    Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Key West Airport are updated daily.

  • How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to Key West Airport?

  • How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Key West Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santa Ana J. Wayne/Orange Cnty Airport to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The travel and health documents you'll need for your trip to Key West Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Key West Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Santa Ana, California to Key West?

Best airlines flying from Santa Ana, California to Key West

Compare and see reviews for airlines that fly from Santa Ana, California to Key West with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $348Free CancellationRating
7.1
11,651 reviews
Search American Airlines flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to Key West?

Finding the right flight to Key West from Santa Ana is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Key West quick and easy, saving you time and money.

Can I find flights from Santa Ana to Key West with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Santa Ana to Key West flights to just show those with flexible booking policies.

How can momondo help me find flights from Santa Ana to Key West?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Santa Ana to Key West.

I’m not ready to book a flight from Santa Ana to Key West right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Key West from Santa Ana. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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