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Cheap flights from Santa Ana to Florida Keys from $43

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Ana to Florida Keys departing on 10/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Santa Ana to Florida Keys

Cheap round-trip flights

Frontier Logo
11:52 am - 12:44 amSNA-MIA
9h 52m1 stop
Frontier Logo
6:45 am - 12:13 pmMIA-SNA
8h 28m1 stop
$167Frontier
Find Deal
Thu, Sep 25 - Sat, Sep 27
Frontier Logo
11:52 am - 12:44 amSNA-MIA
9h 52m1 stop
Frontier Logo
6:45 am - 12:13 pmMIA-SNA
8h 28m1 stop
$177Frontier
Find Deal
Thu, Sep 25 - Sat, Sep 27
Spirit Airlines Logo
6:45 am - 6:42 pmSNA-MIA
8h 57m1 stop
Spirit Airlines Logo
3:47 pm - 8:59 pmMIA-SNA
8h 12m1 stop
$217Spirit Airlines
Find Deal
Mon, Nov 3 - Mon, Nov 10
Spirit Airlines Logo
1:00 pm - 10:40 pmSNA-MIA
30h 40m2 stops
Spirit Airlines Logo
7:23 pm - 1:15 pmMIA-SNA
20h 52m1 stop
$218Spirit Airlines
Find Deal
Thu, Sep 18 - Mon, Sep 22
American Airlines Logo
6:45 am - 4:18 pmSNA-EYW
6h 33m1 stop
American Airlines Logo
2:32 pm - 8:03 pmEYW-SNA
8h 31m1 stop
$389American Airlines
Find Deal
Sat, Oct 25 - Sat, Nov 1
American Airlines Logo
6:45 am - 7:22 pmSNA-EYW
9h 37m2 stops
American Airlines Logo
2:32 pm - 8:03 pmEYW-SNA
8h 31m1 stop
$432American Airlines
Find Deal
Sat, Oct 25 - Sat, Nov 1
Delta Logo
7:00 am - 8:06 pmSNA-EYW
10h 06m2 stops
Delta Logo
12:22 pm - 9:43 pmEYW-SNA
12h 21m2 stops
$528Delta
Find Deal
Sat, Oct 25 - Sat, Nov 1
United Airlines Logo
11:53 am - 1:52 pmSNA-EYW
22h 59m3 stops
United Airlines Logo
4:00 pm - 10:23 amEYW-SNA
21h 23m2 stops
$650United Airlines
Find Deal
Sat, Oct 25 - Sat, Nov 1
Delta Logo
6:45 am - 5:12 pmSNA-EYW
7h 27m1 stop
Delta Logo
7:00 am - 12:42 pmEYW-SNA
8h 42m1 stop
$652Delta
Find Deal
Sat, Sep 27 - Wed, Oct 1
United Airlines Logo
1:48 pm - 2:29 pmSNA-EYW
21h 41m2 stops
United Airlines Logo
3:12 pm - 9:17 amEYW-SNA
21h 05m3 stops
$693United Airlines
Find Deal
Sat, Sep 27 - Wed, Oct 1

Frontier flights from Santa Ana to Florida Keys

Our best Frontier deals on Santa Ana to Florida Keys flight tickets
Frontier
Sep 25
SNA11:52 amSanta Ana J. Wayne/Orange Cnty
9h 52m
1 stop
MIA12:44 amMiami
Sep 27
MIA6:45 amMiami
8h 28m
1 stop
SNA12:13 pmSanta Ana J. Wayne/Orange Cnty
$167
Find similar
Frontier
Sep 25
SNA11:52 amSanta Ana J. Wayne/Orange Cnty
9h 52m
1 stop
MIA12:44 amMiami
Sep 27
MIA6:45 amMiami
8h 28m
1 stop
SNA12:13 pmSanta Ana J. Wayne/Orange Cnty
$177
Find similar
Frontier
Oct 3
SNA11:52 amSanta Ana J. Wayne/Orange Cnty
9h 52m
1 stop
MIA12:44 amMiami
Oct 6
MIA6:00 amMiami
8h 07m
1 stop
SNA11:07 amSanta Ana J. Wayne/Orange Cnty
$192
Find similar

Alaska Airlines flights from Santa Ana to Florida Keys

Our best Alaska Airlines deals on Santa Ana to Florida Keys flight tickets
Alaska Airlines
Sep 9
SNA7:21 pmSanta Ana J. Wayne/Orange Cnty
19h 24m
1 stop
MIA5:45 pmMiami
Sep 16
MIA6:45 pmMiami
18h 04m
1 stop
SNA9:49 amSanta Ana J. Wayne/Orange Cnty
$758
Find similar
Alaska Airlines
Sep 10
SNA2:03 pmSanta Ana J. Wayne/Orange Cnty
24h 42m
2 stops
MIA5:45 pmMiami
Sep 17
MIA6:45 pmMiami
25h 26m
1 stop
SNA5:11 pmSanta Ana J. Wayne/Orange Cnty
$1,188
Find similar
Alaska Airlines
Sep 10
SNA6:45 amSanta Ana J. Wayne/Orange Cnty
10h 33m
1 stop
MIA8:18 pmMiami
Sep 14
MIA6:45 pmMiami
17h 47m
2 stops
SNA9:32 amSanta Ana J. Wayne/Orange Cnty
$11,971
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Santa Ana to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 4, 2025.
Use the filters below to find and compare flights from Santa Ana to Florida Keys that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santa AnaMiami

SNA - MIA

SNAMIA

Santa Ana J. Wayne/Orange Cnty

Thu 9/25

11:52 am-12:44 am

1 stop9h 52m

Miami

Sat 9/27

6:45 am-12:13 pm

1 stop8h 28m

$167

Santa AnaMiami

SNA - MIA

SNAMIA

Santa Ana J. Wayne/Orange Cnty

Thu 9/25

11:52 am-12:44 am

1 stop9h 52m

Miami

Sat 9/27

6:45 am-12:13 pm

1 stop8h 28m

$177

Santa AnaMiami

SNA - MIA

SNAMIA

Santa Ana J. Wayne/Orange Cnty

Mon 11/3

6:45 am-6:42 pm

1 stop8h 57m

Miami

Mon 11/10

3:47 pm-8:59 pm

1 stop8h 12m

$217

Santa AnaMiami

SNA - MIA

SNAMIA

Santa Ana J. Wayne/Orange Cnty

Thu 9/18

1:00 pm-10:40 pm

2 stops30h 40m

Miami

Mon 9/22

7:23 pm-1:15 pm

1 stop20h 52m

$218

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Sat 10/25

6:45 am-4:18 pm

1 stop6h 33m

Key West

Sat 11/1

2:32 pm-8:03 pm

1 stop8h 31m

$389

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Sat 10/25

6:45 am-7:22 pm

2 stops9h 37m

Key West

Sat 11/1

2:32 pm-8:03 pm

1 stop8h 31m

$432

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Sat 10/25

7:00 am-8:06 pm

2 stops10h 06m

Key West

Sat 11/1

12:22 pm-9:43 pm

2 stops12h 21m

$528

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Sat 10/25

11:53 am-1:52 pm

3 stops22h 59m

Key West

Sat 11/1

4:00 pm-10:23 am

2 stops21h 23m

$650

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Sat 9/27

6:45 am-5:12 pm

1 stop7h 27m

Key West

Wed 10/1

7:00 am-12:42 pm

1 stop8h 42m

$652

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Sat 9/27

1:48 pm-2:29 pm

2 stops21h 41m

Key West

Wed 10/1

3:12 pm-9:17 am

3 stops21h 05m

$693

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Florida Keys from

How to get the cheapest flight ticket from Santa Ana to Florida Keys

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Florida Keys?

The month of June is another great option to travel to Florida Keys, with average flight prices from Santa Ana averaging around $366.

What is the cheapest time of day to depart on your flight to Florida Keys?

According to our data, the cheapest time of day to fly to Florida Keys is in the afternoon. momondo users have found flights departing from Santa Ana to Florida Keys in the afternoon for as low as $379. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights in the morning are often more expensive with an average ticket price of $1,271.

How far in advance should I book a flight to Florida Keys?

You are more likely to see cheaper flights to Florida Keys from Santa Ana when booking weeks ahead of your departure date. In general, you can expect to find flights to Florida Keys for around $440 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Florida Keys from Santa Ana for as low as $308 on momondo.

Can stopping save me money on Santa Ana to Florida Keys flights?

No. A direct flight is the cheapest option for a flight between Santa Ana to Florida Keys.

Cheap Santa Ana to Florida Keys flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana to Florida Keys

Direct flights

None
There are no direct flights from Santa Ana to Florida Keys. There are no popular flight routes from Santa Ana to Florida Keys.
Search flight deals

  • When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Florida Keys?

    Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Florida Keys were last updated today.

  • How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to Florida Keys?

  • How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Florida Keys?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santa Ana J. Wayne/Orange Cnty Airport to Florida Keys.

  • What documentation or ID do you need to fly to Florida Keys?

    The necessary travel and health documents for your Florida Keys trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Santa Ana to Florida Keys?

Best airlines flying from Santa Ana to Florida Keys

Compare and see reviews for airlines that fly from Santa Ana to Florida Keys with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $308Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
DeltaPriceFrom $347Free CancellationRating
7.9
7,977 reviews
Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to Florida Keys?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Santa Ana to Florida Keys for you.

Can I find flights from Santa Ana to Florida Keys with flexible booking policies on momondo?

Flights from Santa Ana to Florida Keys with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Santa Ana to Florida Keys?

momondo provides multiple filters to help you find the best flight to Florida Keys from Santa Ana. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Santa Ana to Florida Keys right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Florida Keys, momondo offers a useful price alert feature which will track prices for flights to Florida Keys from Santa Ana and alert you when they change.

An easier way to manage your Florida Keys trip

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Find better results for your trip to Florida Keys

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