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Cheap flights from Santa Ana, California to Florida Keys from $76

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Ana, California to Florida Keys departing on 3/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Santa Ana, California to Florida Keys

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
12:25 pm - 5:14 am
SNA
-
MIA
13h 49m
1 stop
Frontier Logo
6:25 am - 11:40 am
MIA
-
SNA
8h 15m
1 stop
$201Frontier
Sat, Feb 14 - Sat, Feb 21
Frontier Logo
12:25 pm - 5:14 am
SNA
-
MIA
13h 49m
1 stop
Frontier Logo
5:50 am - 9:47 am
MIA
-
SNA
30h 57m
1 stop
$217Frontier
Sat, Feb 28 - Sat, Mar 7
Frontier Logo
11:31 am - 5:14 am
SNA
-
MIA
14h 43m
1 stop
Frontier Logo
5:50 am - 10:47 am
MIA
-
SNA
7h 57m
1 stop
$220Frontier
Mon, Mar 2 - Mon, Mar 9
American Airlines Logo
6:45 am - 10:37 pm
SNA
-
EYW
12h 52m
2 stops
American Airlines Logo
2:06 pm - 9:17 pm
EYW
-
SNA
10h 11m
1 stop
$481American Airlines
Thu, Feb 19 - Thu, Feb 26
American Airlines Logo
7:50 am - 11:56 pm
SNA
-
EYW
13h 06m
2 stops
American Airlines Logo
2:45 pm - 8:23 pm
EYW
-
SNA
8h 38m
1 stop
$511American Airlines
Sun, Feb 8 - Fri, Feb 20
Spirit Airlines Logo
1:20 pm - 1:30 pm
SNA
-
EYW
21h 10m
3 stops
Spirit Airlines Logo
2:25 pm - 12:25 pm
EYW
-
SNA
25h 00m
3 stops
$519Spirit Airlines
Thu, Feb 5 - Mon, Feb 9
Spirit Airlines Logo
4:37 pm - 1:30 pm
SNA
-
EYW
17h 53m
3 stops
Spirit Airlines Logo
2:25 pm - 12:25 pm
EYW
-
SNA
25h 00m
2 stops
$540Spirit Airlines
Thu, Feb 5 - Mon, Feb 9
American Airlines Logo
8:45 am - 11:56 pm
SNA
-
EYW
12h 11m
2 stops
American Airlines Logo
2:45 pm - 9:56 pm
EYW
-
SNA
10h 11m
2 stops
$552American Airlines
Sun, Feb 8 - Fri, Feb 20
American Airlines Logo
5:01 pm - 11:11 am
SNA
-
EYW
15h 10m
2 stops
American Airlines Logo
7:45 am - 6:32 pm
EYW
-
SNA
13h 47m
2 stops
$569American Airlines
Sat, Feb 21 - Sat, Feb 28
Spirit Airlines Logo
1:20 pm - 1:30 pm
SNA
-
EYW
21h 10m
2 stops
Spirit Airlines Logo
2:25 pm - 12:25 pm
EYW
-
SNA
25h 00m
2 stops
$587Spirit Airlines
Thu, Feb 5 - Mon, Feb 9

Frontier flights from Santa Ana, California to Florida Keys

Our best Frontier deals on Santa Ana, California to Florida Keys flight tickets
Frontier
Feb 14
SNA12:25 pmSanta Ana J. Wayne/Orange Cnty
13h 49m
1 stop
MIA5:14 amMiami
Feb 21
MIA6:25 amMiami
8h 15m
1 stop
SNA11:40 amSanta Ana J. Wayne/Orange Cnty
$201
Frontier
Feb 28
SNA12:25 pmSanta Ana J. Wayne/Orange Cnty
13h 49m
1 stop
MIA5:14 amMiami
Mar 7
MIA5:50 amMiami
30h 57m
1 stop
SNA9:47 amSanta Ana J. Wayne/Orange Cnty
$217
Frontier
Mar 2
SNA11:31 amSanta Ana J. Wayne/Orange Cnty
14h 43m
1 stop
MIA5:14 amMiami
Mar 9
MIA5:50 amMiami
7h 57m
1 stop
SNA10:47 amSanta Ana J. Wayne/Orange Cnty
$220

Spirit Airlines flights from Santa Ana, California to Florida Keys

Our best Spirit Airlines deals on Santa Ana, California to Florida Keys flight tickets
Spirit Airlines
Feb 17
SNA1:20 pmSanta Ana J. Wayne/Orange Cnty
28h 31m
2 stops
MIA8:51 pmMiami
Feb 24
MIA9:18 pmMiami
26h 39m
3 stops
SNA8:57 pmSanta Ana J. Wayne/Orange Cnty
$259
Spirit Airlines
Feb 19
SNA4:37 pmSanta Ana J. Wayne/Orange Cnty
25h 14m
2 stops
MIA8:51 pmMiami
Feb 24
MIA9:53 pmMiami
20h 49m
2 stops
SNA3:42 pmSanta Ana J. Wayne/Orange Cnty
$261
Spirit Airlines
Feb 19
SNA6:45 amSanta Ana J. Wayne/Orange Cnty
11h 06m
2 stops
MIA8:51 pmMiami
Feb 24
MIA9:18 pmMiami
21h 24m
3 stops
SNA3:42 pmSanta Ana J. Wayne/Orange Cnty
$275

momondo Fare Finder

 
Customize your flight search to find flights from Santa Ana, California to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 21, 2026.
Use the filters below to find and compare flights from Santa Ana, California to Florida Keys that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santa AnaMiami

SNA - MIA

SNAMIA

Santa Ana J. Wayne/Orange Cnty

Sat 2/14

12:25 pm-5:14 am

1 stop13h 49m

Miami

Sat 2/21

6:25 am-11:40 am

1 stop8h 15m

$201

Santa AnaMiami

SNA - MIA

SNAMIA

Santa Ana J. Wayne/Orange Cnty

Sat 2/28

12:25 pm-5:14 am

1 stop13h 49m

Miami

Sat 3/7

5:50 am-9:47 am

1 stop30h 57m

$217

Santa AnaMiami

SNA - MIA

SNAMIA

Santa Ana J. Wayne/Orange Cnty

Mon 3/2

11:31 am-5:14 am

1 stop14h 43m

Miami

Mon 3/9

5:50 am-10:47 am

1 stop7h 57m

$220

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Thu 2/19

6:45 am-10:37 pm

2 stops12h 52m

Key West

Thu 2/26

2:06 pm-9:17 pm

1 stop10h 11m

$481

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Sun 2/8

7:50 am-11:56 pm

2 stops13h 06m

Key West

Fri 2/20

2:45 pm-8:23 pm

1 stop8h 38m

$511

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Thu 2/5

1:20 pm-1:30 pm

3 stops21h 10m

Key West

Mon 2/9

2:25 pm-12:25 pm

3 stops25h 00m

$519

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Thu 2/5

4:37 pm-1:30 pm

3 stops17h 53m

Key West

Mon 2/9

2:25 pm-12:25 pm

2 stops25h 00m

$540

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Sun 2/8

8:45 am-11:56 pm

2 stops12h 11m

Key West

Fri 2/20

2:45 pm-9:56 pm

2 stops10h 11m

$552

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Sat 2/21

5:01 pm-11:11 am

2 stops15h 10m

Key West

Sat 2/28

7:45 am-6:32 pm

2 stops13h 47m

$569

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Thu 2/5

1:20 pm-1:30 pm

2 stops21h 10m

Key West

Mon 2/9

2:25 pm-12:25 pm

2 stops25h 00m

$587

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Florida Keys from

How to get the cheapest flight ticket from Santa Ana, California to Florida Keys

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Florida Keys?

The month of August is another great option to travel to Florida Keys, with average flight prices from Santa Ana, California averaging around $366.

How far in advance should I book a flight to Florida Keys?

You are more likely to see cheaper flights to Florida Keys from Santa Ana, California when booking weeks ahead of your departure date. In general, you can expect to find flights to Florida Keys for around $430 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Florida Keys from Santa Ana, California for as low as $329 on momondo.

Can stopping save me money on Santa Ana, California to Florida Keys flights?

No. A direct flight is the cheapest option for a flight between Santa Ana, California to Florida Keys.

Cheap Santa Ana, California to Florida Keys flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana, California to Florida Keys

Fastest flight time

7h 00m

Direct flights

None
The fastest flight from Santa Ana, California to Florida Keys takes 7h 00m
There are no direct flights from Santa Ana, California to Florida Keys. There are no popular flight routes from Santa Ana, California to Florida Keys.
Search flight deals

  • When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Florida Keys?

    Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Florida Keys were last updated today.

  • How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to Florida Keys?

  • How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Florida Keys?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santa Ana J. Wayne/Orange Cnty Airport to Florida Keys.

  • What documentation or ID do you need to fly to Florida Keys?

    The necessary travel and health documents for your Florida Keys trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Santa Ana, California to Florida Keys?

Best airlines flying from Santa Ana, California to Florida Keys

Compare and see reviews for airlines that fly from Santa Ana, California to Florida Keys with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $348Free CancellationRating
7.2
11,169 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to Florida Keys?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Santa Ana to Florida Keys for you.

Can I find flights from Santa Ana to Florida Keys with flexible booking policies on momondo?

Flights from Santa Ana to Florida Keys with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Santa Ana to Florida Keys?

momondo provides multiple filters to help you find the best flight to Florida Keys from Santa Ana. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Santa Ana to Florida Keys right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Florida Keys, momondo offers a useful price alert feature which will track prices for flights to Florida Keys from Santa Ana and alert you when they change.

An easier way to manage your Florida Keys trip

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