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Cheap flights from Santa Ana, California to Florida Keys from $58

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Ana, California to Florida Keys departing on 2/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Santa Ana, California to Florida Keys

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
12:17 pm - 11:59 pm
SNA
-
MIA
8h 42m1 stop
Multiple Airlines Logo
5:30 am - 12:25 pm
MIA
-
SNA
33h 55m2 stops
$152Multiple Airlines
Fri, Feb 6 - Mon, Feb 9
Multiple Airlines Logo
12:17 pm - 11:59 pm
SNA
-
MIA
8h 42m1 stop
Multiple Airlines Logo
9:26 pm - 8:57 pm
MIA
-
SNA
26h 31m2 stops
$161Multiple Airlines
Fri, Feb 6 - Sat, Feb 7
American Airlines Logo
10:55 am - 11:56 pm
SNA
-
EYW
10h 01m2 stops
American Airlines Logo
2:06 pm - 9:17 pm
EYW
-
SNA
10h 11m1 stop
$314American Airlines
Wed, Mar 11 - Wed, Mar 18
Delta Logo
6:45 am - 7:40 pm
SNA
-
EYW
9h 55m1 stop
Delta Logo
7:10 am - 4:13 pm
EYW
-
SNA
12h 03m2 stops
$354Delta
Fri, Jan 9 - Tue, Jan 13
American Airlines Logo
10:55 am - 11:56 pm
SNA
-
EYW
10h 01m2 stops
American Airlines Logo
1:38 pm - 9:17 pm
EYW
-
SNA
10h 39m2 stops
$359American Airlines
Wed, Mar 11 - Wed, Mar 18
United Airlines Logo
10:52 am - 10:19 pm
SNA
-
EYW
8h 27m1 stop
United Airlines Logo
4:45 pm - 9:45 pm
EYW
-
SNA
8h 00m1 stop
$400United Airlines
Wed, Mar 11 - Wed, Mar 18
Delta Logo
6:45 am - 7:40 pm
SNA
-
EYW
9h 55m1 stop
Delta Logo
2:45 pm - 8:04 pm
EYW
-
SNA
8h 19m1 stop
$408Delta
Fri, Jan 9 - Tue, Jan 13
Spirit Airlines Logo
11:11 am - 1:30 pm
SNA
-
EYW
23h 19m3 stops
Spirit Airlines Logo
12:20 pm - 10:16 am
EYW
-
SNA
24h 56m3 stops
$454Spirit Airlines
Sun, Dec 21 - Thu, Dec 25
United Airlines Logo
6:25 pm - 1:03 pm
SNA
-
EYW
39h 38m3 stops
United Airlines Logo
4:15 pm - 10:24 pm
EYW
-
SNA
9h 09m1 stop
$480United Airlines
Fri, Jan 9 - Tue, Jan 13
Spirit Airlines Logo
11:11 am - 1:30 pm
SNA
-
EYW
23h 19m3 stops
Spirit Airlines Logo
2:30 pm - 10:27 pm
EYW
-
SNA
10h 57m2 stops
$482Spirit Airlines
Thu, Dec 18 - Mon, Dec 22

Frontier flights from Santa Ana, California to Florida Keys

Our best Frontier deals on Santa Ana, California to Florida Keys flight tickets
Frontier
Feb 6
SNA12:17 pmSanta Ana J. Wayne/Orange Cnty
8h 42m
1 stop
MIA11:59 pmMiami
Feb 11
MIA8:10 amMiami
34h 50m
2 stops
SNA4:00 pmSanta Ana J. Wayne/Orange Cnty
$164
Find similar
Frontier
Jan 9
SNA12:17 pmSanta Ana J. Wayne/Orange Cnty
22h 54m
1 stop
MIA2:11 pmMiami
Jan 12
MIA5:21 pmMiami
24h 39m
2 stops
SNA3:00 pmSanta Ana J. Wayne/Orange Cnty
$192
Find similar
Frontier
Jan 17
SNA3:55 pmSanta Ana J. Wayne/Orange Cnty
30h 23m
2 stops
MIA1:18 amMiami
Jan 21
MIA6:18 pmMiami
19h 40m
1 stop
SNA10:58 amSanta Ana J. Wayne/Orange Cnty
$200
Find similar

American Airlines flights from Santa Ana, California to Florida Keys

Our best American Airlines deals on Santa Ana, California to Florida Keys flight tickets
American Airlines
Jan 14
SNA9:45 amSanta Ana J. Wayne/Orange Cnty
9h 48m
1 stop
MIA10:33 pmMiami
Jan 19
MIA5:15 amMiami
7h 48m
1 stop
SNA10:03 amSanta Ana J. Wayne/Orange Cnty
$215
Find similar
American Airlines
Jan 23
SNA9:45 amSanta Ana J. Wayne/Orange Cnty
9h 48m
1 stop
MIA10:33 pmMiami
Feb 7
MIA7:00 amMiami
11h 33m
1 stop
SNA3:33 pmSanta Ana J. Wayne/Orange Cnty
$223
Find similar
American Airlines
Jan 14
SNA12:38 pmSanta Ana J. Wayne/Orange Cnty
6h 55m
1 stop
MIA10:33 pmMiami
Jan 17
MIA7:00 amMiami
8h 34m
1 stop
SNA12:34 pmSanta Ana J. Wayne/Orange Cnty
$229
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Santa Ana, California to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 4, 2025.
Use the filters below to find and compare flights from Santa Ana, California to Florida Keys that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santa AnaMiami

SNA - MIA

SNAMIA

Santa Ana J. Wayne/Orange Cnty

Fri 2/6

12:17 pm-11:59 pm

1 stop8h 42m

Miami

Mon 2/9

5:30 am-12:25 pm

2 stops33h 55m

$152

Santa AnaMiami

SNA - MIA

SNAMIA

Santa Ana J. Wayne/Orange Cnty

Fri 2/6

12:17 pm-11:59 pm

1 stop8h 42m

Miami

Sat 2/7

9:26 pm-8:57 pm

2 stops26h 31m

$161

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Wed 3/11

10:55 am-11:56 pm

2 stops10h 01m

Key West

Wed 3/18

2:06 pm-9:17 pm

1 stop10h 11m

$314

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Fri 1/9

6:45 am-7:40 pm

1 stop9h 55m

Key West

Tue 1/13

7:10 am-4:13 pm

2 stops12h 03m

$354

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Wed 3/11

10:55 am-11:56 pm

2 stops10h 01m

Key West

Wed 3/18

1:38 pm-9:17 pm

2 stops10h 39m

$359

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Wed 3/11

10:52 am-10:19 pm

1 stop8h 27m

Key West

Wed 3/18

4:45 pm-9:45 pm

1 stop8h 00m

$400

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Fri 1/9

6:45 am-7:40 pm

1 stop9h 55m

Key West

Tue 1/13

2:45 pm-8:04 pm

1 stop8h 19m

$408

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Sun 12/21

11:11 am-1:30 pm

3 stops23h 19m

Key West

Thu 12/25

12:20 pm-10:16 am

3 stops24h 56m

$454

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Fri 1/9

6:25 pm-1:03 pm

3 stops39h 38m

Key West

Tue 1/13

4:15 pm-10:24 pm

1 stop9h 09m

$480

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Thu 12/18

11:11 am-1:30 pm

3 stops23h 19m

Key West

Mon 12/22

2:30 pm-10:27 pm

2 stops10h 57m

$482

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Florida Keys from

How to get the cheapest flight ticket from Santa Ana, California to Florida Keys

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Florida Keys?

The month of September is another great option to travel to Florida Keys, with average flight prices from Santa Ana, California averaging around $371.

What is the cheapest time of day to depart on your flight to Florida Keys?

According to our data, the cheapest time of day to fly to Florida Keys is in the afternoon. momondo users have found flights departing from Santa Ana, California to Florida Keys in the afternoon for as low as $379. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights in the morning are often more expensive with an average ticket price of $1,271.

How far in advance should I book a flight to Florida Keys?

You are more likely to see cheaper flights to Florida Keys from Santa Ana, California when booking weeks ahead of your departure date. In general, you can expect to find flights to Florida Keys for around $442 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Florida Keys from Santa Ana, California for as low as $308 on momondo.

Can stopping save me money on Santa Ana, California to Florida Keys flights?

No. A direct flight is the cheapest option for a flight between Santa Ana, California to Florida Keys.

Cheap Santa Ana, California to Florida Keys flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana, California to Florida Keys

Fastest flight time

7h 01m

Direct flights

None
The fastest flight from Santa Ana, California to Florida Keys takes 7h 01m
There are no direct flights from Santa Ana, California to Florida Keys. There are no popular flight routes from Santa Ana, California to Florida Keys.
Search flight deals

  • When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Florida Keys?

    Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Florida Keys were last updated today.

  • How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to Florida Keys?

  • How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Florida Keys?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santa Ana J. Wayne/Orange Cnty Airport to Florida Keys.

  • What documentation or ID do you need to fly to Florida Keys?

    The necessary travel and health documents for your Florida Keys trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Santa Ana, California to Florida Keys?

Best airlines flying from Santa Ana, California to Florida Keys

Compare and see reviews for airlines that fly from Santa Ana, California to Florida Keys with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $344Free CancellationRating
7.2
11,047 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to Florida Keys?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Santa Ana to Florida Keys for you.

Can I find flights from Santa Ana to Florida Keys with flexible booking policies on momondo?

Flights from Santa Ana to Florida Keys with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Santa Ana to Florida Keys?

momondo provides multiple filters to help you find the best flight to Florida Keys from Santa Ana. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Santa Ana to Florida Keys right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Florida Keys, momondo offers a useful price alert feature which will track prices for flights to Florida Keys from Santa Ana and alert you when they change.

An easier way to manage your Florida Keys trip

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Find better results for your trip to Florida Keys

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