Cheap flights from San Francisco to Spain from $326

If you don’t want to visit Spain in November, then you should wait until March to fly from San Francisco, when ticket prices are also cheap, with an average price of $575.

The cheapest day to depart from San Francisco to Spain is on a Tuesday when prices can be found for as low as $737. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from San Francisco to Spain for around $925.

Flying to Spain from San Francisco in the evening is the least expensive time of day to depart. momondo users have found prices as low as $703 when looking at flights departing in the evening. In contrast, the most expensive time of day to depart to Spain is in the afternoon when prices are around $870.

Fly from San Francisco to Madrid Barajas for the best San Francisco - Spain flight prices

You are more likely to see cheaper flights to Spain from San Francisco when booking weeks ahead of your departure date. In general, you can expect to find flights to Spain for around $724 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Spain from San Francisco for as low as $649 on momondo.

There are 3 cabin classes available to choose from on San Francisco to Spain flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

British Airways, Delta, and American Airlines are the most popular carriers operating from San Francisco to Spain

United Airlines, TAP AIR PORTUGAL and Iberia are the top three most popular airlines that fly to Spain from San Francisco according to our data. United Airlines is the first choice among our users, with 45% of people opting to fly with this airline when traveling to Spain. Keep in mind that there are 21 different airlines that fly to Spain on a routine basis, so you have a few additional options to choose from.

Historically, on average around 16% of flights between San Francisco and Spain have experienced a delay on any given week. The average delay length over the past 12 months has been 180 minutes.

Generally, flights departing at night tend to experience fewer delays. Flights in the early afternoon have, in the past, seen delays more frequently in comparison.

Monday is statistically the day of the week which experiences the fewest number of delays on this flight route. Saturday has historically seen more delays on average compared to the rest of the week.

According to our data, LEVEL have had the least number of delays on this route over the last 12 months; with about 11% of their flights experiencing any sort of delay.

6 flights are operational daily from San Francisco to Spain as of May 2026. The most popular departure time for this route is 5:00PM, with 100% of flights per day taking off in the afternoon.

As of May 2026, 44 flights take off from San Francisco and land in Spain each week. The most common flight departure day for this route is Tue, with 20% of weekly flights taking off on this day.