Cheap flights from San Francisco to Rome from $375

The cheapest month to fly to Rome from San Francisco is in February. Flight prices, which tend to average around $636, are often lower during this time because this is during the off-season. If you aren’t able to travel to Rome during the month of February, then flying in January is also cheap. Prices for this month can be found on momondo for an average of $715.

The cheapest day to depart on your flight to Rome is on a Monday when prices can be found for as low as $957. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Friday as prices are generally higher than usual. According to our data, the average ticket price to Rome on Friday is $1,120.

Fly from San Francisco to Rome Fiumicino for the best San Francisco - Rome flight prices

You are more likely to see cheaper flights to Rome from San Francisco when booking weeks ahead of your departure date. In general, you can expect to find flights to Rome for around $936 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Rome from San Francisco for as low as $858 on momondo.

There are 3 cabin classes available to choose from on San Francisco to Rome flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 26% on your flight if you consider stops on a San Francisco to Rome flight.

TAP AIR PORTUGAL is the most popular carrier operating from San Francisco to Rome

ITA Airways, Condor and United Airlines are the top three most popular airlines that fly to Rome from San Francisco according to our data. ITA Airways is the first choice among our users, with 61% of people opting to fly with this airline when traveling to Rome. Keep in mind that there are 11 different airlines that fly to Rome on a routine basis, so you have a few additional options to choose from.

Historically, on average around 23% of flights between San Francisco and Rome have experienced a delay on any given week. The average delay length over the past 12 months has been 144 minutes.

Generally, flights departing in the early afternoon tend to experience fewer delays. Flights in the early afternoon have, in the past, seen delays more frequently in comparison.

Sunday is statistically the day of the week which experiences the fewest number of delays on this flight route. Wednesday has historically seen more delays on average compared to the rest of the week.

According to our data, United Airlines have had the least number of delays on this route over the last 12 months; with about 22% of their flights experiencing any sort of delay.

Frankfurt am Main (FRA) was the most common stop: 56% of momondo users choosing 1-stop flights on this route connected there.

Flights via Calgary (YYC) offer the lowest average round-trip price of $560.

Flights connecting via Calgary (YYC) have the shortest average one-way travel time: 14h 40m.

Frankfurt am Main (FRA) has the shortest average layover time for this route: 1h 45m.

The number of flights available between San Francisco and Rome is 3 per day as of October 2026. The most frequent departure time is 4:00PM, with 100% of daily flights leaving in the afternoon.

As of October 2026, there are 21 flights per week flying from San Francisco to Rome. The most common day of the week flights depart is Mon, with 24% of flights taking off on this day.