Cheap flights from San Francisco to Rome from $375

The cheapest month to fly to Rome from San Francisco is in February. Flight prices, which tend to average around $629, are often lower during this time because this is during the off-season. If you aren’t able to travel to Rome during the month of February, then flying in October is also cheap. Prices for this month can be found on momondo for an average of $679.

The cheapest day to depart on your flight to Rome is on a Monday when prices can be found for as low as $877. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Friday as prices are generally higher than usual. According to our data, the average ticket price to Rome on Friday is $997.

Fly from San Francisco to Rome Fiumicino for the best San Francisco - Rome flight prices

You are more likely to see cheaper flights to Rome from San Francisco when booking weeks ahead of your departure date. In general, you can expect to find flights to Rome for around $856 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Rome from San Francisco for as low as $749 on momondo.

There are 3 cabin classes available to choose from on San Francisco to Rome flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

No. A direct flight is the cheapest option for a flight between San Francisco to Rome.

TAP AIR PORTUGAL and British Airways are the most popular carriers operating from San Francisco to Rome

ITA Airways, United Airlines and Condor are the top three most popular airlines that fly to Rome from San Francisco according to our data. ITA Airways is the first choice among our users, with 69% of people opting to fly with this airline when traveling to Rome. Keep in mind that there are 17 different airlines that fly to Rome on a routine basis, so you have a few additional options to choose from.

Historically, on average around 20% of flights between San Francisco and Rome have experienced a delay on any given week. The average delay length over the past 12 months has been 144 minutes.

Generally, flights departing in the evening tend to experience fewer delays. Flights at night have, in the past, seen delays more frequently in comparison.

Friday is statistically the day of the week which experiences the fewest number of delays on this flight route. Monday has historically seen more delays on average compared to the rest of the week.

According to our data, ITA Airways have had the least number of delays on this route over the last 12 months; with about 16% of their flights experiencing any sort of delay.

Frankfurt am Main (FRA) was the most common stop: 47% of momondo users choosing 1-stop flights on this route connected there.

Flights via Atlanta (ATL) offer the lowest average round-trip price of $494.

Flights connecting via Paris (CDG) have the shortest average one-way travel time: 14h 13m.

Paris (CDG) has the shortest average layover time for this route: 1h 20m.

The number of flights available between San Francisco and Rome is 1 per day as of March 2026. The most frequent departure time is 4:00PM, with 100% of daily flights leaving in the afternoon.

As of March 2026, there are 8 flights per week flying from San Francisco to Rome. The most common day of the week flights depart is Sat, with 50% of flights taking off on this day.