Cheap flights from San Francisco Bay Area to St. Louis from $86

In general, September is the cheapest month to fly from San Francisco Bay Area to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $388. The month of October is another great option to travel to St. Louis, with average flight prices from San Francisco Bay Area averaging around $411.

The cheapest day to depart on your flight to St. Louis is on a Thursday when prices can be found for as low as $450. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Monday because tickets tend to average around $568. These prices are subject to change though, so be sure to set up a Price Alert for flights to St. Louis.

Flying to St. Louis from San Francisco Bay Area at noon is the least expensive time of day to depart. momondo users have found prices as low as $382 when looking at flights departing at noon. In the afternoon is when there is more demand to fly to St. Louis, so prices are often more expensive at around $736 per ticket.

Fly from San Francisco to Lambert-St Louis for the best San Francisco Bay Area - Lambert-St Louis flight prices

You are more likely to see cheaper flights to St. Louis from San Francisco Bay Area when booking weeks ahead of your departure date. In general, you can expect to find flights to St. Louis for around $484 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to St. Louis from San Francisco Bay Area for as low as $403 on momondo.

There are 4 cabin classes available to choose from on San Francisco Bay Area to Lambert-St Louis flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Frontier, Delta, and Alaska Airlines are the most popular carriers operating from San Francisco Bay Area to Lambert-St Louis

Southwest, United Airlines and Frontier are the top three most popular airlines that fly to St. Louis from San Francisco Bay Area according to our data. Southwest is the first choice among our users, with 44% of people opting to fly with this airline when traveling to St. Louis. Keep in mind that there are 5 different airlines that fly to St. Louis on a routine basis, so you have a few additional options to choose from.

4 flights are operational daily from San Francisco Bay Area to St. Louis as of April 2026. The most popular departure time for this route is 4:00PM, with 66% of flights per day taking off in the afternoon.

29 flights are operational weekly from San Francisco Bay Area to St. Louis as of April 2026. The most popular departure day for this route is Mon, with 21% of flights per week taking off on this day.