What airlines fly to South Carolina?

American Airlines, Delta and Southwest are the top three most popular airlines that fly to South Carolina from San Antonio according to our data. American Airlines is the first choice among our users, with 41% of people opting to fly with this airline when traveling to South Carolina. Keep in mind that there are 4 different airlines that fly to South Carolina on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from San Antonio to South Carolina?

Delta, United Airlines, and American Airlines are the most popular carriers operating from San Antonio to South Carolina

How many flights depart from San Antonio to South Carolina on average per week?

The number of flights available between San Antonio and South Carolina is 1 per week as of November 2026. The most frequent departure day is Mon, with 100% of weekly flights leaving on this day.

When did momondo last update prices for flights from San Antonio Airport to South Carolina?

Prices for flights from San Antonio Airport to South Carolina were last updated today.

How many operators does momondo search for flights from San Antonio Airport to South Carolina?

As of November 2026, there are 4 operators available to choose from for flights from San Antonio Airport to South Carolina.

How old do you have to be to fly from San Antonio Airport to South Carolina?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from San Antonio Airport to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The necessary travel and health documents for your South Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$162 Cheap Flights from San Antonio to South Carolina in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from San Antonio to South Carolina

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

1:50 pm - 7:25 pmSAT San Antonio-GSP Greenville

4h 35m1 stop Nashville Intl

7:30 am - 12:45 pmGSP Greenville-SAT San Antonio

6h 15m1 stop Baltimore/Washington

$279Southwest

Thu, Feb 4 - Thu, Feb 11

1:45 pm - 7:56 pmSAT San Antonio-GSP Greenville

5h 11m1 stop Atlanta Hartsfield-Jackson

5:40 am - 9:48 amGSP Greenville-SAT San Antonio

5h 08m1 stop Atlanta Hartsfield-Jackson

$279Delta

Tue, Dec 1 - Tue, Dec 8

6:16 am - 1:18 pmSAT San Antonio-GSP Greenville

6h 02m1 stop Atlanta Hartsfield-Jackson

12:18 pm - 5:31 pmGSP Greenville-SAT San Antonio

6h 13m1 stop Atlanta Hartsfield-Jackson

$279Delta

Tue, Dec 1 - Wed, Dec 9

1:50 pm - 7:25 pmSAT San Antonio-GSP Greenville

4h 35m1 stop Nashville Intl

7:15 am - 1:25 pmGSP Greenville-SAT San Antonio

7h 10m2 stops Nashville Intl Dallas Love Field

$284Southwest

Thu, Feb 4 - Wed, Feb 10

5:32 pm - 11:57 pmSAT San Antonio-CHS Charleston

5h 25m1 stop Charlotte Douglas

7:18 pm - 12:07 amCHS Charleston-SAT San Antonio

5h 49m1 stop Dallas/Fort Worth

$339American Airlines

Fri, Dec 4 - Mon, Dec 7

7:00 am - 2:25 pmSAT San Antonio-CHS Charleston

6h 25m1 stop Charlotte Douglas

2:32 pm - 8:55 pmCHS Charleston-SAT San Antonio

7h 23m1 stop Charlotte Douglas

$339American Airlines

Wed, Feb 17 - Sat, Feb 27

5:15 am - 5:48 pmSAT San Antonio-MYR Myrtle Beach Intl

11h 33m2 stops Houston George Bush Intcntl Newark

11:27 am - 11:13 pmMYR Myrtle Beach Intl-SAT San Antonio

12h 46m2 stops Newark Chicago O'Hare Intl

$349United Airlines

Tue, Jan 19 - Tue, Jan 26

9:25 am - 8:03 amSAT San Antonio-MYR Myrtle Beach Intl

21h 38m2 stops Raleigh-Durham Fort Lauderdale

2:46 pm - 11:40 amMYR Myrtle Beach Intl-SAT San Antonio

21h 54m1 stop Orlando

$353Multiple Airlines

Thu, Dec 3 - Thu, Dec 10

1:14 pm - 8:38 amSAT San Antonio-CHS Charleston

18h 24m1 stop Orlando

3:27 pm - 6:01 pmCHS Charleston-SAT San Antonio

27h 34m2 stops Orlando Denver Intl

$366Multiple Airlines

Fri, Dec 4 - Mon, Dec 7

7:05 am - 2:24 pmSAT San Antonio-CAE Columbia Metropolitan

6h 19m1 stop Washington, D.C. Dulles Intl

2:26 pm - 11:14 pmCAE Columbia Metropolitan-SAT San Antonio

9h 48m1 stop Chicago O'Hare Intl

$369United Airlines

Thu, Jan 7 - Sat, Jan 9

Cheap last minute flights

Enter your travel dates to find the best prices.

6:34 am - 7:08 pmSAT San Antonio-CAE Columbia Metropolitan

11h 34m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

5:37 pm - 10:57 pmCAE Columbia Metropolitan-SAT San Antonio

6h 20m1 stop Chicago O'Hare Intl

$469United Airlines

Wed, Nov 4 - Sat, Nov 7

1:15 pm - 9:02 pmSAT San Antonio-CAE Columbia Metropolitan

6h 47m1 stop Chicago O'Hare Intl

5:37 pm - 10:57 pmCAE Columbia Metropolitan-SAT San Antonio

6h 20m1 stop Chicago O'Hare Intl

$501United Airlines

Wed, Nov 4 - Sat, Nov 7

5:30 am - 6:25 pmSAT San Antonio-MYR Myrtle Beach Intl

11h 55m1 stop Baltimore/Washington

3:25 pm - 9:25 pmMYR Myrtle Beach Intl-SAT San Antonio

7h 00m1 stop Baltimore/Washington

$598Southwest

Wed, Nov 4 - Wed, Nov 18

5:30 am - 6:25 pmSAT San Antonio-MYR Myrtle Beach Intl

11h 55m1 stop Baltimore/Washington

3:25 pm - 11:10 pmMYR Myrtle Beach Intl-SAT San Antonio

8h 45m2 stops Baltimore/Washington Nashville Intl

$604Southwest

Wed, Nov 4 - Wed, Nov 18

5:13 pm - 10:05 amSAT San Antonio-MYR Myrtle Beach Intl

15h 52m1 stop Orlando

6:12 pm - 7:25 pmMYR Myrtle Beach Intl-SAT San Antonio

26h 13m2 stops Tampa Denver Intl

$617Multiple Airlines

Mon, Nov 9 - Mon, Nov 16

4:32 pm - 10:54 pmSAT San Antonio-MYR Myrtle Beach Intl

5h 22m1 stop Atlanta Hartsfield-Jackson

6:51 pm - 12:33 amMYR Myrtle Beach Intl-SAT San Antonio

6h 42m1 stop Atlanta Hartsfield-Jackson

$639Delta

Mon, Nov 9 - Mon, Nov 16

6:30 am - 1:33 pmSAT San Antonio-MYR Myrtle Beach Intl

6h 03m1 stop Atlanta Hartsfield-Jackson

6:00 am - 9:59 amMYR Myrtle Beach Intl-SAT San Antonio

4h 59m1 stop Atlanta Hartsfield-Jackson

$639Delta

Mon, Nov 9 - Tue, Nov 17

5:13 pm - 10:05 amSAT San Antonio-MYR Myrtle Beach Intl

15h 52m1 stop Orlando

4:08 pm - 9:34 pmMYR Myrtle Beach Intl-SAT San Antonio

30h 26m2 stops Orlando Las Vegas Harry Reid Intl

$665Multiple Airlines

Mon, Nov 9 - Tue, Nov 17

1:09 pm - 8:07 pmSAT San Antonio-CAE Columbia Metropolitan

5h 58m1 stop Charlotte Douglas

5:10 pm - 10:56 pmCAE Columbia Metropolitan-SAT San Antonio

6h 46m1 stop Dallas/Fort Worth

$712American Airlines

Fri, Nov 6 - Tue, Nov 10

6:00 am - 1:20 pmSAT San Antonio-CAE Columbia Metropolitan

6h 20m1 stop Dallas/Fort Worth

6:02 pm - 10:53 pmCAE Columbia Metropolitan-SAT San Antonio

5h 51m1 stop Charlotte Douglas

$721American Airlines

Thu, Nov 5 - Sun, Nov 8

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American Airlines flights from San Antonio to South Carolina

Our best American Airlines deals on San Antonio to South Carolina flight tickets

American Airlines

Nov 23

SAT5:49 pmSan Antonio

5h 06m

1 stop

CHS11:55 pmCharleston

Dec 1

CHS4:59 pmCharleston

7h 04m

1 stop

SAT11:03 pmSan Antonio

$339

American Airlines

Dec 11

SAT2:05 pmSan Antonio

7h 18m

1 stop

CHS10:23 pmCharleston

Dec 14

CHS7:18 pmCharleston

5h 49m

1 stop

SAT12:07 amSan Antonio

$363

American Airlines

Dec 3

SAT2:05 pmSan Antonio

7h 19m

1 stop

CHS10:24 pmCharleston

Dec 7

CHS7:18 pmCharleston

5h 49m

1 stop

SAT12:07 amSan Antonio

$366

Delta flights from San Antonio to South Carolina

Our best Delta deals on San Antonio to South Carolina flight tickets

Delta

Dec 1

SAT6:16 amSan Antonio

6h 02m

1 stop

GSP1:18 pmGreenville

Dec 9

GSP12:18 pmGreenville

6h 13m

1 stop

SAT5:31 pmSan Antonio

$279

Delta

Nov 24

SAT6:30 pmSan Antonio

4h 08m

1 stop

GSP11:38 pmGreenville

Nov 26

GSP6:00 amGreenville

4h 54m

1 stop

SAT9:54 amSan Antonio

$319

Delta

Jan 19

SAT7:39 amSan Antonio

5h 14m

1 stop

MYR1:53 pmMyrtle Beach Intl

Jan 26

MYR6:00 amMyrtle Beach Intl

4h 54m

1 stop

SAT9:54 amSan Antonio

$339

momondo Fare Finder

Use the filters below to find and compare flights from San Antonio to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San AntonioGreenville

SAT San Antonio - GSP Greenville

SATGSP

San Antonio

Thu 2/4

1:50 pm-7:25 pm

1 stop4h 35m

Greenville

Thu 2/11

7:30 am-12:45 pm

1 stop6h 15m

$279

Quickest round-trip

San AntonioGreenville

SAT San Antonio - GSP Greenville

SATGSP

San Antonio

Tue 12/1

1:45 pm-7:56 pm

1 stop5h 11m

Greenville

Tue 12/8

5:40 am-9:48 am

1 stop5h 08m

$279

San AntonioGreenville

SAT San Antonio - GSP Greenville

SATGSP

San Antonio

Tue 12/1

6:16 am-1:18 pm

1 stop6h 02m

Greenville

Wed 12/9

12:18 pm-5:31 pm

1 stop6h 13m

$279

San AntonioGreenville

SAT San Antonio - GSP Greenville

SATGSP

San Antonio

Thu 2/4

1:50 pm-7:25 pm

1 stop4h 35m

Greenville

Wed 2/10

7:15 am-1:25 pm

2 stops7h 10m

$284

San AntonioCharleston

SAT San Antonio - CHS Charleston

SATCHS

San Antonio

Fri 12/4

5:32 pm-11:57 pm

1 stop5h 25m

Charleston

Mon 12/7

7:18 pm-12:07 am

1 stop5h 49m

$339

San AntonioCharleston

SAT San Antonio - CHS Charleston

SATCHS

San Antonio

Wed 2/17

7:00 am-2:25 pm

1 stop6h 25m

Charleston

Sat 2/27

2:32 pm-8:55 pm

1 stop7h 23m

$339

San AntonioMyrtle Beach

SAT San Antonio - MYR Myrtle Beach Intl

SATMYR

San Antonio

Tue 1/19

5:15 am-5:48 pm

2 stops11h 33m

Myrtle Beach Intl

Tue 1/26

11:27 am-11:13 pm

2 stops12h 46m

$349

San AntonioMyrtle Beach

SAT San Antonio - MYR Myrtle Beach Intl

SATMYR

San Antonio

Thu 12/3

9:25 am-8:03 am

2 stops21h 38m

Myrtle Beach Intl

Thu 12/10

2:46 pm-11:40 am

1 stop21h 54m

$353

San AntonioCharleston

SAT San Antonio - CHS Charleston

SATCHS

San Antonio

Fri 12/4

1:14 pm-8:38 am

1 stop18h 24m

Charleston

Mon 12/7

3:27 pm-6:01 pm

2 stops27h 34m

$366

San AntonioColumbia

SAT San Antonio - CAE Columbia Metropolitan

SATCAE

San Antonio

Thu 1/7

7:05 am-2:24 pm

1 stop6h 19m

Columbia Metropolitan

Sat 1/9

2:26 pm-11:14 pm

1 stop9h 48m

$369

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from San Antonio to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from San Antonio is in January. Flight prices, which tend to average around $324, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of January, then book flights to South Carolina from San Antonio during October instead. Flights to South Carolina in October, while not as cheap as those in January, still average around $407.

Can stopping save me money on San Antonio to South Carolina flights?

You could potentially save up to 39% on your flight if you consider stops on a San Antonio to South Carolina flight.

Cheap San Antonio to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Antonio to South Carolina

Best Price Found	$162
Fastest flight time	2h 43m
Direct flights	None

The best one-way flight to South Carolina from San Antonio in the past 72 hours is $162. The best round-trip flight deal from San Antonio to South Carolina found on momondo in the last 72 hours is $279.

The fastest flight from San Antonio to South Carolina takes 2h 43m

There are no direct flights from San Antonio to South Carolina. There are no popular flight routes from San Antonio to South Carolina.

Search flight deals

Frequently asked questions about flying from San Antonio to South Carolina

When did momondo last update prices for flights from San Antonio Airport to South Carolina?
Prices for flights from San Antonio Airport to South Carolina were last updated today.
How many operators does momondo search for flights from San Antonio Airport to South Carolina?
As of November 2026, there are 4 operators available to choose from for flights from San Antonio Airport to South Carolina.
How old do you have to be to fly from San Antonio Airport to South Carolina?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from San Antonio Airport to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The necessary travel and health documents for your South Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from San Antonio to South Carolina

Compare and see reviews for airlines that fly from San Antonio to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $229	Free Cancellation	Rating 7.8 8,700 reviews	Search Delta flights
United Airlines	PriceFrom $277	Free Cancellation	Rating 7.3 10,460 reviews	Search United Airlines flights
American Airlines	PriceFrom $279	Free Cancellation	Rating 7.0 12,224 reviews	Search American Airlines flights
Southwest	PriceFrom $333	Free Cancellation	Rating 8.0 4,219 reviews	Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from San Antonio to South Carolina?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from San Antonio to South Carolina. momondo saves you time and could save you money on your trip.

Can I find flights from San Antonio to South Carolina with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to South Carolina from San Antonio with this policy.

How can momondo help me find flights from San Antonio to South Carolina?

momondo helps you find the best flight between San Antonio and South Carolina by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from San Antonio to South Carolina right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to South Carolina from San Antonio. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.