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Cheap flights from Rochester to Greenville from $161

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Rochester to Greenville departing on 12/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

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American Airlines Logo
11:25 am - 5:56 pmROC-GSP
6h 31m1 stop
American Airlines Logo
6:21 pm - 11:00 pmGSP-ROC
4h 39m1 stop
$321American Airlines
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Thu, Dec 4 - Mon, Dec 8
Southwest Logo
6:10 am - 5:35 pmROC-GSP
11h 25m2 stops
Southwest Logo
6:15 pm - 9:55 pmGSP-ROC
3h 40m1 stop
$326Southwest
Find Deal
Thu, Jan 8 - Mon, Jan 12
Delta Logo
6:17 am - 11:02 amROC-GSP
4h 45m1 stop
Delta Logo
7:25 am - 11:40 amGSP-ROC
4h 15m1 stop
$332Delta
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Wed, Dec 10 - Sun, Dec 14
Southwest Logo
12:20 pm - 8:30 pmROC-GSP
8h 10m1 stop
Southwest Logo
8:00 am - 11:45 amGSP-ROC
3h 45m1 stop
$337Southwest
Find Deal
Tue, Mar 24 - Thu, Mar 26
Southwest Logo
3:50 pm - 7:40 pmROC-GSP
3h 50m1 stop
Southwest Logo
4:45 pm - 10:30 pmGSP-ROC
5h 45m1 stop
$342Southwest
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Fri, Dec 5 - Tue, Dec 9
Southwest Logo
3:50 pm - 7:40 pmROC-GSP
3h 50m1 stop
Southwest Logo
7:40 am - 5:50 pmGSP-ROC
10h 10m2 stops
$347Southwest
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Fri, Dec 5 - Tue, Dec 9
American Airlines Logo
5:06 pm - 11:04 pmROC-GSP
5h 58m2 stops
American Airlines Logo
6:01 am - 11:26 amGSP-ROC
5h 25m2 stops
$352American Airlines
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Fri, Dec 5 - Tue, Dec 9
United Airlines Logo
9:48 pm - 2:58 amROC-GSP
5h 10m1 stop
United Airlines Logo
9:19 am - 4:46 pmGSP-ROC
7h 27m1 stop
$377United Airlines
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Sun, Nov 30 - Sun, Dec 7
Delta Logo
6:30 pm - 11:36 pmROC-GSP
5h 06m1 stop
Delta Logo
6:45 am - 11:35 amGSP-ROC
4h 50m1 stop
$392Delta
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Mon, Apr 6 - Fri, Apr 10
United Airlines Logo
6:00 am - 4:53 pmROC-GSP
10h 53m2 stops
United Airlines Logo
12:19 pm - 10:52 pmGSP-ROC
10h 33m2 stops
$409United Airlines
Find Deal
Thu, Dec 4 - Mon, Dec 8

American Airlines flights from Rochester to Greenville

Our best American Airlines deals on Rochester to Greenville flight tickets
American Airlines
Dec 4
ROC11:25 amGreater Rochester Intl
6h 31m
1 stop
GSP5:56 pmGreenville
Dec 8
GSP6:21 pmGreenville
4h 39m
1 stop
ROC11:00 pmGreater Rochester Intl
$321
Find similar
American Airlines
Dec 5
ROC5:06 pmGreater Rochester Intl
5h 58m
2 stops
GSP11:04 pmGreenville
Dec 9
GSP6:01 amGreenville
5h 25m
2 stops
ROC11:26 amGreater Rochester Intl
$352
Find similar
American Airlines
Jan 8
ROC11:19 amGreater Rochester Intl
7h 48m
2 stops
GSP7:07 pmGreenville
Jan 12
GSP11:00 amGreenville
6h 45m
2 stops
ROC5:45 pmGreater Rochester Intl
$354
Find similar

Southwest flights from Rochester to Greenville

Our best Southwest deals on Rochester to Greenville flight tickets
Southwest
Jan 8
ROC6:10 amGreater Rochester Intl
11h 25m
2 stops
GSP5:35 pmGreenville
Jan 12
GSP6:15 pmGreenville
3h 40m
1 stop
ROC9:55 pmGreater Rochester Intl
$326
Find similar
Southwest
Mar 24
ROC12:20 pmGreater Rochester Intl
8h 10m
1 stop
GSP8:30 pmGreenville
Mar 26
GSP8:00 amGreenville
3h 45m
1 stop
ROC11:45 amGreater Rochester Intl
$337
Find similar
Southwest
Dec 5
ROC3:50 pmGreater Rochester Intl
3h 50m
1 stop
GSP7:40 pmGreenville
Dec 9
GSP4:45 pmGreenville
5h 45m
1 stop
ROC10:30 pmGreater Rochester Intl
$342
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Rochester to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 10, 2025.
Use the filters below to find and compare flights from Rochester to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

RochesterGreenville

ROC - GSP

ROCGSP

Greater Rochester Intl

Thu 12/4

11:25 am-5:56 pm

1 stop6h 31m

Greenville

Mon 12/8

6:21 pm-11:00 pm

1 stop4h 39m

$321

RochesterGreenville

ROC - GSP

ROCGSP

Greater Rochester Intl

Thu 1/8

6:10 am-5:35 pm

2 stops11h 25m

Greenville

Mon 1/12

6:15 pm-9:55 pm

1 stop3h 40m

$326

RochesterGreenville

ROC - GSP

ROCGSP

Greater Rochester Intl

Wed 12/10

6:17 am-11:02 am

1 stop4h 45m

Greenville

Sun 12/14

7:25 am-11:40 am

1 stop4h 15m

$332

RochesterGreenville

ROC - GSP

ROCGSP

Greater Rochester Intl

Tue 3/24

12:20 pm-8:30 pm

1 stop8h 10m

Greenville

Thu 3/26

8:00 am-11:45 am

1 stop3h 45m

$337

RochesterGreenville

ROC - GSP

ROCGSP

Greater Rochester Intl

Fri 12/5

3:50 pm-7:40 pm

1 stop3h 50m

Greenville

Tue 12/9

4:45 pm-10:30 pm

1 stop5h 45m

$342

RochesterGreenville

ROC - GSP

ROCGSP

Greater Rochester Intl

Fri 12/5

3:50 pm-7:40 pm

1 stop3h 50m

Greenville

Tue 12/9

7:40 am-5:50 pm

2 stops10h 10m

$347

RochesterGreenville

ROC - GSP

ROCGSP

Greater Rochester Intl

Fri 12/5

5:06 pm-11:04 pm

2 stops5h 58m

Greenville

Tue 12/9

6:01 am-11:26 am

2 stops5h 25m

$352

RochesterGreenville

ROC - GSP

ROCGSP

Greater Rochester Intl

Sun 11/30

9:48 pm-2:58 am

1 stop5h 10m

Greenville

Sun 12/7

9:19 am-4:46 pm

1 stop7h 27m

$377

RochesterGreenville

ROC - GSP

ROCGSP

Greater Rochester Intl

Mon 4/6

6:30 pm-11:36 pm

1 stop5h 06m

Greenville

Fri 4/10

6:45 am-11:35 am

1 stop4h 50m

$392

RochesterGreenville

ROC - GSP

ROCGSP

Greater Rochester Intl

Thu 12/4

6:00 am-4:53 pm

2 stops10h 53m

Greenville

Mon 12/8

12:19 pm-10:52 pm

2 stops10h 33m

$409

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 18 resultsSorted by cheapest first
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See travel insights to Greenville from

How to get the cheapest flight ticket from Rochester to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Greenville?

The month of July is another great option to travel to Greenville, with average flight prices from Rochester averaging around $316.

What is the cheapest day to depart on your flight to Greenville?

According to our data, Tuesday is the cheapest day to fly to Greenville from Rochester. The lowest ticket price found for a Tuesday departure recently was $304. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. If your travel schedule is flexible, try to avoid departing on a Friday because tickets tend to average around $435. These prices are subject to change though, so be sure to set up a Price Alert for flights to Greenville.

What is the cheapest time of day to depart on your flight to Greenville?

Our most recent data shows that the best time of day to fly to Greenville is at noon. Flights from Rochester to Greenville during this time can be as low as $335. Flights to Greenville are more costly in the afternoon, with an average ticket price of $413. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest Greater Rochester Intl to Greenville flight route?

Fly from Greater Rochester Intl to Greenville for the best Greater Rochester Intl - Greenville flight prices

How far in advance should I book a flight to Greenville?

You are more likely to see cheaper flights to Greenville from Rochester when booking weeks ahead of your departure date. In general, you can expect to find flights to Greenville for around $364 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Greenville from Rochester for as low as $252 on momondo.

What cabin class options are available on Greater Rochester Intl to Greenville flights?

There is only 1 cabin class available to choose from on Greater Rochester Intl to Greenville flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Rochester to Greenville flight prices changed over time?

As of November 2025, prices for Rochester to Greenville flights are approximately 129% more expensive when compared to flights at the same time last year.

When to book flights from Rochester to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from Rochester to Greenville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Rochester to Greenville (ROC to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Rochester to Greenville

Direct flights

None
There are no direct flights from Rochester to Greenville. There are no popular flight routes from Rochester to Greenville.
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  • How far is Greater Rochester Intl to Greenville by plane?

    A flight from Greater Rochester Intl to Greenville will travel around 627.7 mi. 3h 50m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Greater Rochester Intl Airport to Greenville Airport?

    Prices for flights from Greater Rochester Intl Airport to Greenville Airport refresh daily.

  • How many operators does momondo search for flights from Greater Rochester Intl Airport to Greenville Airport?

  • How old do you have to be to fly from Greater Rochester Intl Airport to Greenville Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Greater Rochester Intl Airport to Greenville Airport.

  • What documentation or ID do you need to fly to Greenville Airport?

    The required travel and health documents for your Greenville Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Greenville Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Rochester to Greenville?

  • What is the most popular airline from Rochester to Greenville?

Best airlines flying from Rochester to Greenville

Compare and see reviews for airlines that fly from Rochester to Greenville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $216Free CancellationRating
7.2
11,047 reviews
Search American Airlines flights
DeltaPriceFrom $216Free CancellationRating
7.9
8,004 reviews
Search Delta flights
SouthwestPriceFrom $246Free CancellationRating
8.0
4,238 reviews
Search Southwest flights
United AirlinesPriceFrom $289Free CancellationRating
7.4
9,012 reviews
Search United Airlines flights

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Anderson
Simpsonville
Greenwood
Seneca
Greer
Duncan

Why use momondo?

Why should I use momondo to find a flight deal from Rochester to Greenville?

It is quick and easy to find Rochester to Greenville flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Greenville that suits you.

Can I find flights from Rochester to Greenville with flexible booking policies on momondo?

All flight searches from Rochester to Greenville on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Rochester to Greenville?

Once all potential Rochester to Greenville flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Rochester to Greenville right now. Can momondo alert me if prices change?

Price alerts on flights to Greenville from Rochester are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Greenville trip

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