What is the cheapest airline that flies from Roanoke to South Carolina?

United Airlines, Delta, and American Airlines are the most popular carriers operating from Roanoke to South Carolina

When did momondo last update prices for flights from Roanoke Airport to South Carolina?

Prices for flights from Roanoke Airport to South Carolina are refreshed on a daily basis.

How many operators does momondo search for flights from Roanoke Airport to South Carolina?

As of September 2026, there is 1 operator available to choose from for flights from Roanoke Airport to South Carolina.

How old do you have to be to fly from Roanoke Airport to South Carolina?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Roanoke Airport to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$260 Cheap Flights from Roanoke to South Carolina in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Roanoke to South Carolina

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:00 am - 9:42 amROA Roanoke-CHS Charleston

3h 42m1 stop Atlanta Hartsfield-Jackson

5:55 pm - 12:23 amCHS Charleston-ROA Roanoke

6h 28m1 stop Atlanta Hartsfield-Jackson

$291Delta

Tue, Mar 2 - Wed, Mar 10

3:25 pm - 8:40 pmROA Roanoke-CHS Charleston

5h 15m1 stop Atlanta Hartsfield-Jackson

6:30 am - 10:34 amCHS Charleston-ROA Roanoke

4h 04m1 stop Atlanta Hartsfield-Jackson

$291Delta

Tue, Mar 2 - Sat, Mar 6

6:00 am - 9:42 amROA Roanoke-CHS Charleston

3h 42m1 stop Atlanta Hartsfield-Jackson

9:30 am - 2:40 pmCHS Charleston-ROA Roanoke

5h 10m1 stop Atlanta Hartsfield-Jackson

$291Delta

Wed, Mar 3 - Tue, Mar 9

6:00 am - 9:42 amROA Roanoke-CHS Charleston

3h 42m1 stop Atlanta Hartsfield-Jackson

5:30 am - 10:34 amCHS Charleston-ROA Roanoke

5h 04m1 stop Atlanta Hartsfield-Jackson

$291Delta

Sat, Feb 27 - Wed, Mar 10

3:25 pm - 8:40 pmROA Roanoke-CHS Charleston

5h 15m1 stop Atlanta Hartsfield-Jackson

5:55 pm - 12:23 amCHS Charleston-ROA Roanoke

6h 28m1 stop Atlanta Hartsfield-Jackson

$291Delta

Wed, Mar 3 - Wed, Mar 10

6:00 am - 11:26 amROA Roanoke-CHS Charleston

5h 26m1 stop Atlanta Hartsfield-Jackson

5:30 am - 10:34 amCHS Charleston-ROA Roanoke

5h 04m1 stop Atlanta Hartsfield-Jackson

$291Delta

Sat, Feb 27 - Sat, Mar 6

3:25 pm - 6:54 pmROA Roanoke-CHS Charleston

3h 29m1 stop Atlanta Hartsfield-Jackson

5:30 am - 10:34 amCHS Charleston-ROA Roanoke

5h 04m1 stop Atlanta Hartsfield-Jackson

$291Delta

Sat, Feb 27 - Tue, Mar 9

3:25 pm - 8:40 pmROA Roanoke-CHS Charleston

5h 15m1 stop Atlanta Hartsfield-Jackson

6:30 am - 10:34 amCHS Charleston-ROA Roanoke

4h 04m1 stop Atlanta Hartsfield-Jackson

$291Delta

Wed, Mar 3 - Sat, Mar 6

6:10 pm - 9:50 pmROA Roanoke-CHS Charleston

3h 40m1 stop Charlotte Douglas

5:02 am - 8:31 amCHS Charleston-ROA Roanoke

3h 29m1 stop Charlotte Douglas

$369American Airlines

Fri, Oct 9 - Sun, Oct 11

4:14 pm - 9:53 pmROA Roanoke-CHS Charleston

5h 39m1 stop Charlotte Douglas

6:27 am - 10:30 amCHS Charleston-ROA Roanoke

4h 03m1 stop Charlotte Douglas

$452American Airlines

Fri, Nov 6 - Sun, Nov 8

Cheap last minute flights

Enter your travel dates to find the best prices.

3:27 pm - 6:56 pmROA Roanoke-CHS Charleston

3h 29m1 stop Charlotte Douglas

8:10 am - 1:27 pmCHS Charleston-ROA Roanoke

5h 17m1 stop Charlotte Douglas

$383American Airlines

Fri, Oct 2 - Tue, Oct 6

11:15 am - 4:50 pmROA Roanoke-CHS Charleston

5h 35m1 stop Charlotte Douglas

5:05 am - 8:31 amCHS Charleston-ROA Roanoke

3h 26m1 stop Charlotte Douglas

$383American Airlines

Sat, Oct 3 - Mon, Oct 5

11:15 am - 4:50 pmROA Roanoke-CHS Charleston

5h 35m1 stop Charlotte Douglas

5:02 am - 8:31 amCHS Charleston-ROA Roanoke

3h 29m1 stop Charlotte Douglas

$383American Airlines

Sat, Oct 3 - Thu, Oct 8

11:15 am - 4:50 pmROA Roanoke-CHS Charleston

5h 35m1 stop Charlotte Douglas

5:31 pm - 8:59 pmCHS Charleston-ROA Roanoke

3h 28m1 stop Charlotte Douglas

$393American Airlines

Thu, Oct 1 - Sat, Oct 3

3:27 pm - 6:56 pmROA Roanoke-CHS Charleston

3h 29m1 stop Charlotte Douglas

8:10 am - 1:27 pmCHS Charleston-ROA Roanoke

5h 17m1 stop Charlotte Douglas

$393American Airlines

Fri, Oct 2 - Tue, Oct 6

6:15 am - 9:44 amROA Roanoke-MYR Myrtle Beach Intl

3h 29m1 stop Washington, D.C. Dulles Intl

5:00 pm - 10:59 pmMYR Myrtle Beach Intl-ROA Roanoke

5h 59m1 stop Chicago O'Hare Intl

$459United Airlines

Wed, Sep 30 - Wed, Oct 7

3:27 pm - 6:56 pmROA Roanoke-CHS Charleston

3h 29m1 stop Charlotte Douglas

8:41 pm - 11:51 pmCHS Charleston-ROA Roanoke

3h 10m1 stop Charlotte Douglas

$484American Airlines

Fri, Oct 2 - Sun, Oct 4

6:00 am - 10:07 amROA Roanoke-MYR Myrtle Beach Intl

4h 07m1 stop Atlanta Hartsfield-Jackson

6:58 pm - 12:27 amMYR Myrtle Beach Intl-ROA Roanoke

5h 29m1 stop Atlanta Hartsfield-Jackson

$505Delta

Wed, Sep 30 - Tue, Oct 6

6:00 am - 10:07 amROA Roanoke-MYR Myrtle Beach Intl

4h 07m1 stop Atlanta Hartsfield-Jackson

3:56 pm - 9:51 pmMYR Myrtle Beach Intl-ROA Roanoke

5h 55m1 stop Atlanta Hartsfield-Jackson

$505Delta

Wed, Sep 30 - Sat, Oct 3

6:00 am - 10:07 amROA Roanoke-MYR Myrtle Beach Intl

4h 07m1 stop Atlanta Hartsfield-Jackson

2:16 pm - 10:49 pmMYR Myrtle Beach Intl-ROA Roanoke

8h 33m2 stops Atlanta Hartsfield-Jackson New York LaGuardia

$556Delta

Wed, Sep 30 - Tue, Oct 6

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Delta flights from Roanoke to South Carolina

Our best Delta deals on Roanoke to South Carolina flight tickets

Delta

Feb 27

ROA3:25 pmRoanoke

3h 29m

1 stop

CHS6:54 pmCharleston

Mar 9

CHS5:30 amCharleston

5h 04m

1 stop

ROA10:34 amRoanoke

$291

Delta

Feb 27

ROA6:00 amRoanoke

5h 26m

1 stop

CHS11:26 amCharleston

Mar 8

CHS2:25 pmCharleston

4h 48m

1 stop

ROA7:13 pmRoanoke

$305

Delta

Feb 26

ROA6:00 amRoanoke

3h 42m

1 stop

CHS9:42 amCharleston

Mar 11

CHS5:30 amCharleston

5h 04m

1 stop

ROA10:34 amRoanoke

$319

United Airlines flights from Roanoke to South Carolina

Our best United Airlines deals on Roanoke to South Carolina flight tickets

United Airlines

Oct 9

ROA8:05 pmRoanoke

4h 10m

1 stop

CHS12:15 amCharleston

Oct 13

CHS7:53 pmCharleston

3h 51m

1 stop

ROA11:44 pmRoanoke

$349

United Airlines

Oct 9

ROA8:05 pmRoanoke

4h 10m

1 stop

CHS12:15 amCharleston

Oct 19

CHS7:53 pmCharleston

3h 51m

1 stop

ROA11:44 pmRoanoke

$354

United Airlines

Oct 9

ROA8:05 pmRoanoke

4h 10m

1 stop

CHS12:15 amCharleston

Oct 11

CHS6:00 amCharleston

3h 48m

1 stop

ROA9:48 amRoanoke

$369

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RoanokeCharleston

ROA Roanoke - CHS Charleston

ROACHS

Roanoke

Tue 3/2

6:00 am-9:42 am

1 stop3h 42m

Charleston

Wed 3/10

5:55 pm-12:23 am

1 stop6h 28m

$291

RoanokeCharleston

ROA Roanoke - CHS Charleston

ROACHS

Roanoke

Tue 3/2

3:25 pm-8:40 pm

1 stop5h 15m

Charleston

Sat 3/6

6:30 am-10:34 am

1 stop4h 04m

$291

RoanokeCharleston

ROA Roanoke - CHS Charleston

ROACHS

Roanoke

Wed 3/3

6:00 am-9:42 am

1 stop3h 42m

Charleston

Tue 3/9

9:30 am-2:40 pm

1 stop5h 10m

$291

RoanokeCharleston

ROA Roanoke - CHS Charleston

ROACHS

Roanoke

Sat 2/27

6:00 am-9:42 am

1 stop3h 42m

Charleston

Wed 3/10

5:30 am-10:34 am

1 stop5h 04m

$291

RoanokeCharleston

ROA Roanoke - CHS Charleston

ROACHS

Roanoke

Wed 3/3

3:25 pm-8:40 pm

1 stop5h 15m

Charleston

Wed 3/10

5:55 pm-12:23 am

1 stop6h 28m

$291

RoanokeCharleston

ROA Roanoke - CHS Charleston

ROACHS

Roanoke

Sat 2/27

6:00 am-11:26 am

1 stop5h 26m

Charleston

Sat 3/6

5:30 am-10:34 am

1 stop5h 04m

$291

RoanokeCharleston

ROA Roanoke - CHS Charleston

ROACHS

Roanoke

Sat 2/27

3:25 pm-6:54 pm

1 stop3h 29m

Charleston

Tue 3/9

5:30 am-10:34 am

1 stop5h 04m

$291

RoanokeCharleston

ROA Roanoke - CHS Charleston

ROACHS

Roanoke

Wed 3/3

3:25 pm-8:40 pm

1 stop5h 15m

Charleston

Sat 3/6

6:30 am-10:34 am

1 stop4h 04m

$291

Quickest round-trip

RoanokeCharleston

ROA Roanoke - CHS Charleston

ROACHS

Roanoke

Fri 10/9

6:10 pm-9:50 pm

1 stop3h 40m

Charleston

Sun 10/11

5:02 am-8:31 am

1 stop3h 29m

$369

RoanokeCharleston

ROA Roanoke - CHS Charleston

ROACHS

Roanoke

Fri 11/6

4:14 pm-9:53 pm

1 stop5h 39m

Charleston

Sun 11/8

6:27 am-10:30 am

1 stop4h 03m

$452

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Roanoke to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Roanoke is in January. Flight prices, which tend to average around $228, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of January, then book flights to South Carolina from Roanoke during February instead. Flights to South Carolina in February, while not as cheap as those in January, still average around $298.

Can stopping save me money on Roanoke to South Carolina flights?

You could potentially save up to 25% on your flight if you consider stops on a Roanoke to South Carolina flight.

Cheap Roanoke to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Roanoke to South Carolina

Best Price Found	$260
Fastest flight time	1h 25m
Direct flights	None

The best one-way flight to South Carolina from Roanoke in the past 72 hours is $260. The best round-trip flight deal from Roanoke to South Carolina found on momondo in the last 72 hours is $291.

The fastest flight from Roanoke to South Carolina takes 1h 25m

There are no direct flights from Roanoke to South Carolina. There are no popular flight routes from Roanoke to South Carolina.

Search flight deals

Frequently asked questions about flying from Roanoke to South Carolina

When did momondo last update prices for flights from Roanoke Airport to South Carolina?
Prices for flights from Roanoke Airport to South Carolina are refreshed on a daily basis.
How many operators does momondo search for flights from Roanoke Airport to South Carolina?
As of September 2026, there is 1 operator available to choose from for flights from Roanoke Airport to South Carolina.
How old do you have to be to fly from Roanoke Airport to South Carolina?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Roanoke Airport to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Roanoke to South Carolina

Compare and see reviews for airlines that fly from Roanoke to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $218	Free Cancellation	Rating 7.0 12,097 reviews		Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Roanoke to South Carolina?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Roanoke to South Carolina. momondo saves you time and could save you money on your trip.

Can I find flights from Roanoke to South Carolina with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Roanoke to South Carolina flights to just show those with flexible booking policies.

How can momondo help me find flights from Roanoke to South Carolina?

Once all potential Roanoke to South Carolina flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Roanoke to South Carolina right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Roanoke to South Carolina flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.