Latest deals
Insights
FAQs
Reviews
Price Alerts

Cheap flights from Roanoke to South Carolina from $167

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Roanoke to South Carolina departing on 10/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Roanoke to South Carolina

Cheap round-trip flights

Delta Logo
6:00 am - 9:29 amROA-CHS
3h 29m1 stop
Delta Logo
6:30 am - 10:33 amCHS-ROA
4h 03m1 stop
$229Delta
Find Deal
Wed, Feb 18 - Sat, Feb 21
Multiple Airlines Logo
9:12 pm - 7:47 amROA-CLT
10h 35m1 stop
Multiple Airlines Logo
10:05 pm - 8:23 amCLT-ROA
10h 18m1 stop
$240Multiple Airlines
Find Deal
Mon, Oct 20 - Mon, Oct 27
United Airlines Logo
6:20 am - 10:08 amROA-CHS
3h 48m1 stop
United Airlines Logo
2:52 pm - 6:43 pmCHS-ROA
3h 51m1 stop
$250United Airlines
Find Deal
Thu, Nov 6 - Sat, Nov 8
American Airlines Logo
6:00 am - 10:26 amROA-CHS
4h 26m1 stop
American Airlines Logo
6:35 am - 1:58 pmCHS-ROA
7h 23m1 stop
$259American Airlines
Find Deal
Sun, Oct 19 - Sat, Oct 25
Multiple Airlines Logo
9:12 pm - 7:47 amROA-CLT
10h 35m1 stop
Multiple Airlines Logo
5:49 pm - 8:23 amCLT-ROA
14h 34m2 stops
$272Multiple Airlines
Find Deal
Mon, Oct 20 - Mon, Oct 27
Multiple Airlines Logo
9:49 pm - 7:47 amROA-CLT
9h 58m1 stop
Multiple Airlines Logo
7:20 am - 9:04 pmCLT-ROA
13h 44m1 stop
$273Multiple Airlines
Find Deal
Wed, Oct 15 - Fri, Oct 17
United Airlines Logo
6:45 am - 2:07 pmROA-CHS
7h 22m1 stop
United Airlines Logo
7:45 pm - 11:24 pmCHS-ROA
3h 39m1 stop
$289United Airlines
Find Deal
Tue, Oct 21 - Sat, Oct 25
American Airlines Logo
8:30 am - 7:20 pmROA-CHS
10h 50m2 stops
American Airlines Logo
6:27 pm - 11:41 pmCHS-ROA
5h 14m1 stop
$294American Airlines
Find Deal
Wed, Feb 18 - Sat, Feb 21
Delta Logo
7:59 pm - 11:56 pmROA-CHS
3h 57m1 stop
Delta Logo
5:25 am - 10:40 amCHS-ROA
5h 15m1 stop
$298Delta
Find Deal
Mon, Dec 1 - Wed, Dec 10
Allegiant Air Logo
9:20 pm - 2:35 pmROA-MYR
17h 15m2 stops
Allegiant Air Logo
9:02 pm - 8:22 pmMYR-ROA
23h 20m2 stops
$715Allegiant Air
Find Deal
Thu, Oct 9 - Sun, Oct 12

United Airlines flights from Roanoke to South Carolina

Our best United Airlines deals on Roanoke to South Carolina flight tickets
United Airlines
Nov 6
ROA6:20 amRoanoke
3h 48m
1 stop
CHS10:08 amCharleston
Nov 8
CHS2:52 pmCharleston
3h 51m
1 stop
ROA6:43 pmRoanoke
$250
Find similar
United Airlines
Oct 21
ROA6:45 amRoanoke
7h 22m
1 stop
CHS2:07 pmCharleston
Oct 25
CHS7:45 pmCharleston
3h 39m
1 stop
ROA11:24 pmRoanoke
$289
Find similar
United Airlines
Oct 25
ROA3:00 pmRoanoke
3h 57m
1 stop
CLT6:57 pmCharlotte Douglas
Oct 26
CLT6:00 amCharlotte Douglas
3h 47m
1 stop
ROA9:47 amRoanoke
$318
Find similar

American Airlines flights from Roanoke to South Carolina

Our best American Airlines deals on Roanoke to South Carolina flight tickets
American Airlines
Oct 2
ROA8:09 pmRoanoke
3h 56m
1 stop
CHS12:05 amCharleston
Oct 7
CHS11:36 amCharleston
5h 53m
1 stop
ROA5:29 pmRoanoke
$254
Find similar
American Airlines
Oct 19
ROA6:00 amRoanoke
4h 26m
1 stop
CHS10:26 amCharleston
Oct 25
CHS6:35 amCharleston
7h 23m
1 stop
ROA1:58 pmRoanoke
$259
Find similar
American Airlines
Oct 2
ROA8:09 pmRoanoke
3h 56m
1 stop
CHS12:05 amCharleston
Oct 6
CHS5:00 amCharleston
5h 42m
1 stop
ROA10:42 amRoanoke
$269
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Roanoke to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 24, 2025.
Use the filters below to find and compare flights from Roanoke to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

RoanokeCharleston

ROA - CHS

ROACHS

Roanoke

Wed 2/18

6:00 am-9:29 am

1 stop3h 29m

Charleston

Sat 2/21

6:30 am-10:33 am

1 stop4h 03m

$229

RoanokeCharlotte

ROA - CLT

ROACLT

Roanoke

Mon 10/20

9:12 pm-7:47 am

1 stop10h 35m

Charlotte Douglas

Mon 10/27

10:05 pm-8:23 am

1 stop10h 18m

$240

RoanokeCharleston

ROA - CHS

ROACHS

Roanoke

Thu 11/6

6:20 am-10:08 am

1 stop3h 48m

Charleston

Sat 11/8

2:52 pm-6:43 pm

1 stop3h 51m

$250

RoanokeCharleston

ROA - CHS

ROACHS

Roanoke

Sun 10/19

6:00 am-10:26 am

1 stop4h 26m

Charleston

Sat 10/25

6:35 am-1:58 pm

1 stop7h 23m

$259

RoanokeCharlotte

ROA - CLT

ROACLT

Roanoke

Mon 10/20

9:12 pm-7:47 am

1 stop10h 35m

Charlotte Douglas

Mon 10/27

5:49 pm-8:23 am

2 stops14h 34m

$272

RoanokeCharlotte

ROA - CLT

ROACLT

Roanoke

Wed 10/15

9:49 pm-7:47 am

1 stop9h 58m

Charlotte Douglas

Fri 10/17

7:20 am-9:04 pm

1 stop13h 44m

$273

RoanokeCharleston

ROA - CHS

ROACHS

Roanoke

Tue 10/21

6:45 am-2:07 pm

1 stop7h 22m

Charleston

Sat 10/25

7:45 pm-11:24 pm

1 stop3h 39m

$289

RoanokeCharleston

ROA - CHS

ROACHS

Roanoke

Wed 2/18

8:30 am-7:20 pm

2 stops10h 50m

Charleston

Sat 2/21

6:27 pm-11:41 pm

1 stop5h 14m

$294

RoanokeCharleston

ROA - CHS

ROACHS

Roanoke

Mon 12/1

7:59 pm-11:56 pm

1 stop3h 57m

Charleston

Wed 12/10

5:25 am-10:40 am

1 stop5h 15m

$298

RoanokeMyrtle Beach

ROA - MYR

ROAMYR

Roanoke

Thu 10/9

9:20 pm-2:35 pm

2 stops17h 15m

Myrtle Beach Intl

Sun 10/12

9:02 pm-8:22 pm

2 stops23h 20m

$715

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to South Carolina from

How to get the cheapest flight ticket from Roanoke to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Saturday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $239. The most expensive day to fly to South Carolina is Monday, with ticket prices averaging around $406.

What is the cheapest time of day to depart on your flight to South Carolina?

Our data shows that the cheapest Roanoke to South Carolina flights are usually those with departure times in the evening. Our users have found flights to South Carolina in the evening for as low as $260. Try not to purchase tickets in the afternoon because they tend to be around $373. Of course, these prices can vary depending on the time of year and what airport you fly to.

Cheap Roanoke to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Roanoke to South Carolina

Fastest flight time

1h 25m

Direct flights

Every day

Airports in South Carolina

1 airport
The fastest flight from Roanoke to South Carolina takes 1h 25m
Direct flights go from Roanoke to South Carolina every day.
There is 1 airport near South Carolina: Charlotte Douglas (CLT)
Search flight deals

  • When did momondo last update prices for flights from Roanoke Airport to South Carolina?

    Prices for flights from Roanoke Airport to South Carolina are refreshed on a daily basis.

  • How many operators does momondo search for flights from Roanoke Airport to South Carolina?

  • How old do you have to be to fly from Roanoke Airport to South Carolina?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Roanoke Airport to South Carolina.

  • What documentation or ID do you need to fly to South Carolina?

    The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Roanoke to South Carolina

Compare and see reviews for airlines that fly from Roanoke to South Carolina with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $228Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Roanoke to South Carolina?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Roanoke to South Carolina. momondo saves you time and could save you money on your trip.

Can I find flights from Roanoke to South Carolina with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Roanoke to South Carolina flights to just show those with flexible booking policies.

How can momondo help me find flights from Roanoke to South Carolina?

Once all potential Roanoke to South Carolina flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Roanoke to South Carolina right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Roanoke to South Carolina flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your South Carolina trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Fri 10/24
Fri 10/31
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to South Carolina

Popular cities in South Carolina

Popular flights according to clicks in the last 7 days on momondo
Flights to New Yorkfrom $50
Flights to Los Angelesfrom $44
Flights to Miamifrom $49
Flights to Chicagofrom $65
Flights to Orlandofrom $56
Flights to Las Vegasfrom $44
Flights to San Franciscofrom $60
Flights to Washington, D.C.from $56
Flights to Bostonfrom $68
Flights to Atlantafrom $51
Flights to Dallasfrom $60
Flights to Seattlefrom $86