How many flights depart from Roanoke to South Carolina on average per week?

48 flights are operational weekly from Roanoke to South Carolina as of December 2025. The most popular departure day for this route is Thu, with 19% of flights per week taking off on this day.

What is the cheapest airline that flies from Roanoke to South Carolina?

Delta is the most popular carrier operating from Roanoke to South Carolina

When did momondo last update prices for flights from Roanoke Airport to South Carolina?

Prices for flights from Roanoke Airport to South Carolina are refreshed on a daily basis.

How many operators does momondo search for flights from Roanoke Airport to South Carolina?

As of December 2025, there is 1 operator available to choose from for flights from Roanoke Airport to South Carolina.

How old do you have to be to fly from Roanoke Airport to South Carolina?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Roanoke Airport to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$122 Cheap Flights from Roanoke to South Carolina in 2025/26

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Find the cheapest flights from Roanoke to South Carolina

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

8:00 am - 3:16 pm

ROA

CHS

7h 16m1 stop

6:10 am - 9:41 am

CHS

ROA

3h 31m1 stop

$193American Airlines

sáb., ene. 10 - jue., ene. 15

7:07 pm - 11:55 pm

ROA

MYR

4h 48m1 stop

6:23 am - 9:41 am

MYR

ROA

3h 18m1 stop

$222American Airlines

vie., ene. 2 - sáb., ene. 10

7:59 pm - 11:54 pm

ROA

CHS

3h 55m1 stop

6:00 am - 9:48 am

CHS

ROA

3h 48m1 stop

$244United Airlines

sáb., may. 2 - mié., may. 6

9:08 am - 3:43 pm

ROA

CHS

6h 35m1 stop

5:10 am - 8:42 am

CHS

ROA

3h 32m1 stop

$269American Airlines

jue., ene. 1 - dom., ene. 4

7:03 pm - 10:50 pm

ROA

MYR

3h 47m1 stop

6:59 pm - 12:08 am

MYR

ROA

5h 09m1 stop

$274Delta

mar., dic. 30 - dom., ene. 4

8:14 am - 3:36 pm

ROA

MYR

7h 22m1 stop

6:23 am - 9:41 am

MYR

ROA

3h 18m1 stop

$282American Airlines

vie., ene. 2 - mié., ene. 7

6:00 am - 9:20 am

ROA

MYR

3h 20m1 stop

12:05 pm - 3:05 pm

MYR

ROA

3h 00m1 stop

$297American Airlines

mar., dic. 30 - mié., ene. 7

7:03 pm - 10:50 pm

ROA

MYR

3h 47m1 stop

6:59 pm - 12:08 am

MYR

ROA

5h 09m1 stop

$303Delta

vie., ene. 2 - dom., ene. 4

7:59 pm - 11:54 pm

ROA

CHS

3h 55m1 stop

6:00 am - 9:48 am

CHS

ROA

3h 48m1 stop

$304United Airlines

sáb., may. 2 - mié., may. 6

8:55 pm - 6:37 pm

ROA

MYR

21h 42m1 stop

6:00 am - 2:55 pm

MYR

ROA

32h 55m2 stops

$314Multiple Airlines

mié., dic. 31 - mié., ene. 7

American Airlines flights from Roanoke to South Carolina

Our best American Airlines deals on Roanoke to South Carolina flight tickets

American Airlines

Jan 10

ROA8:00 amRoanoke

7h 16m

1 stop

CHS3:16 pmCharleston

Jan 15

CHS6:10 amCharleston

3h 31m

1 stop

ROA9:41 amRoanoke

$193

Find similar

American Airlines

Jan 2

ROA7:07 pmRoanoke

4h 48m

1 stop

MYR11:55 pmMyrtle Beach Intl

Jan 10

MYR6:23 amMyrtle Beach Intl

3h 18m

1 stop

ROA9:41 amRoanoke

$222

Find similar

American Airlines

Jan 1

ROA9:08 amRoanoke

6h 35m

1 stop

CHS3:43 pmCharleston

Jan 4

CHS5:10 amCharleston

3h 32m

1 stop

ROA8:42 amRoanoke

$269

Find similar

United Airlines flights from Roanoke to South Carolina

Our best United Airlines deals on Roanoke to South Carolina flight tickets

United Airlines

May 2

ROA7:59 pmRoanoke

3h 55m

1 stop

CHS11:54 pmCharleston

May 6

CHS6:00 amCharleston

3h 48m

1 stop

ROA9:48 amRoanoke

$244

Find similar

United Airlines

May 2

ROA7:59 pmRoanoke

3h 55m

1 stop

CHS11:54 pmCharleston

May 6

CHS6:00 amCharleston

3h 48m

1 stop

ROA9:48 amRoanoke

$304

Find similar

United Airlines

May 2

ROA7:59 pmRoanoke

3h 55m

1 stop

CHS11:54 pmCharleston

May 6

CHS6:00 amCharleston

3h 48m

1 stop

ROA9:48 amRoanoke

$314

Find similar

Fly from

Fly to

Route

Depart

Return

Price

RoanokeCharleston

ROA - CHS

ROACHS

Roanoke

sáb. 1/10

8:00 am-3:16 pm

1 stop7h 16m

Charleston

jue. 1/15

6:10 am-9:41 am

1 stop3h 31m

$193

RoanokeMyrtle Beach

ROA - MYR

ROAMYR

Roanoke

vie. 1/2

7:07 pm-11:55 pm

1 stop4h 48m

Myrtle Beach Intl

sáb. 1/10

6:23 am-9:41 am

1 stop3h 18m

$222

RoanokeCharleston

ROA - CHS

ROACHS

Roanoke

sáb. 5/2

7:59 pm-11:54 pm

1 stop3h 55m

Charleston

mié. 5/6

6:00 am-9:48 am

1 stop3h 48m

$244

RoanokeCharleston

ROA - CHS

ROACHS

Roanoke

jue. 1/1

9:08 am-3:43 pm

1 stop6h 35m

Charleston

dom. 1/4

5:10 am-8:42 am

1 stop3h 32m

$269

RoanokeMyrtle Beach

ROA - MYR

ROAMYR

Roanoke

mar. 12/30

7:03 pm-10:50 pm

1 stop3h 47m

Myrtle Beach Intl

dom. 1/4

6:59 pm-12:08 am

1 stop5h 09m

$274

RoanokeMyrtle Beach

ROA - MYR

ROAMYR

Roanoke

vie. 1/2

8:14 am-3:36 pm

1 stop7h 22m

Myrtle Beach Intl

mié. 1/7

6:23 am-9:41 am

1 stop3h 18m

$282

RoanokeMyrtle Beach

ROA - MYR

ROAMYR

Roanoke

mar. 12/30

6:00 am-9:20 am

1 stop3h 20m

Myrtle Beach Intl

mié. 1/7

12:05 pm-3:05 pm

1 stop3h 00m

$297

RoanokeMyrtle Beach

ROA - MYR

ROAMYR

Roanoke

vie. 1/2

7:03 pm-10:50 pm

1 stop3h 47m

Myrtle Beach Intl

dom. 1/4

6:59 pm-12:08 am

1 stop5h 09m

$303

RoanokeCharleston

ROA - CHS

ROACHS

Roanoke

sáb. 5/2

7:59 pm-11:54 pm

1 stop3h 55m

Charleston

mié. 5/6

6:00 am-9:48 am

1 stop3h 48m

$304

RoanokeMyrtle Beach

ROA - MYR

ROAMYR

Roanoke

mié. 12/31

8:55 pm-6:37 pm

1 stop21h 42m

Myrtle Beach Intl

mié. 1/7

6:00 am-2:55 pm

2 stops32h 55m

$314

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Roanoke to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Saturday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $239. The most expensive day to fly to South Carolina is Monday, with ticket prices averaging around $406.

What is the cheapest time of day to depart on your flight to South Carolina?

Our data shows that the cheapest Roanoke to South Carolina flights are usually those with departure times in the evening. Our users have found flights to South Carolina in the evening for as low as $260. Try not to purchase tickets in the afternoon because they tend to be around $373. Of course, these prices can vary depending on the time of year and what airport you fly to.

Cheap Roanoke to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Roanoke to South Carolina

Fastest flight time	1h 29m
Direct flights	Mon, Tue, Wed, Thu, Fri and Sat
Airports in South Carolina	57 airports

The fastest flight from Roanoke to South Carolina takes 1h 29m

Direct flights go from Roanoke to South Carolina on Monday, Tuesday, Wednesday, Thursday, Friday and Saturday. There are no airlines offering direct flights.

There are 57 airports in South Carolina. From Roanoke there are direct flights to Charlotte Douglas (CLT).

Search flight deals

When did momondo last update prices for flights from Roanoke Airport to South Carolina?
Prices for flights from Roanoke Airport to South Carolina are refreshed on a daily basis.
How many operators does momondo search for flights from Roanoke Airport to South Carolina?
As of December 2025, there is 1 operator available to choose from for flights from Roanoke Airport to South Carolina.
How old do you have to be to fly from Roanoke Airport to South Carolina?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Roanoke Airport to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Roanoke to South Carolina

Compare and see reviews for airlines that fly from Roanoke to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $228	Free Cancellation	Rating 7.2 11,050 reviews		Search American Airlines flights

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Why should I use momondo to find a flight deal from Roanoke to South Carolina?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Roanoke to South Carolina. momondo saves you time and could save you money on your trip.

Can I find flights from Roanoke to South Carolina with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Roanoke to South Carolina flights to just show those with flexible booking policies.

How can momondo help me find flights from Roanoke to South Carolina?

Once all potential Roanoke to South Carolina flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Roanoke to South Carolina right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Roanoke to South Carolina flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.