What is the cheapest airline that flies from Roanoke to South Carolina?

United Airlines, American Airlines, and Allegiant Air are the most popular carriers operating from Roanoke to South Carolina

How many flights depart from Roanoke to South Carolina on average per week?

48 flights are operational weekly from Roanoke to South Carolina as of May 2026. The most popular departure day for this route is Mon, with 17% of flights per week taking off on this day.

When did momondo last update prices for flights from Roanoke Airport to South Carolina?

Prices for flights from Roanoke Airport to South Carolina are refreshed on a daily basis.

How many operators does momondo search for flights from Roanoke Airport to South Carolina?

As of May 2026, there is 1 operator available to choose from for flights from Roanoke Airport to South Carolina.

How old do you have to be to fly from Roanoke Airport to South Carolina?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Roanoke Airport to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$179 Cheap Flights from Roanoke to South Carolina in 2026

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Find the cheapest flights from Roanoke to South Carolina

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

7:58 pm - 11:59 pm

ROA

CHS

4h 01m

1 stop

12:10 pm - 5:17 pm

CHS

ROA

5h 07m

1 stop

$299American Airlines

Fri, Jun 5 - Thu, Jun 11

7:59 pm - 11:59 pm

ROA

MYR

4h 00m

1 stop

1:54 pm - 7:17 pm

MYR

ROA

5h 23m

1 stop

$305Delta

Thu, Jun 11 - Wed, Jun 17

6:15 am - 10:16 am

ROA

CHS

4h 01m

1 stop

10:00 am - 2:00 pm

CHS

ROA

4h 00m

1 stop

$319United Airlines

Sat, May 30 - Wed, Jun 3

6:40 am - 1:58 pm

ROA

CHS

7h 18m

1 stop

10:19 am - 2:19 pm

CHS

ROA

4h 00m

1 stop

$331United Airlines

Tue, Sep 1 - Sat, Sep 5

7:30 pm - 11:58 pm

ROA

MYR

4h 28m

1 stop

7:57 pm - 12:32 am

MYR

ROA

4h 35m

1 stop

$367Delta

Fri, Jun 5 - Tue, Jun 16

2:33 pm - 6:54 pm

ROA

MYR

4h 21m

1 stop

6:50 am - 2:24 pm

MYR

ROA

7h 34m

2 stops

$372American Airlines

Sat, Jun 6 - Wed, Jun 17

7:30 pm - 11:58 pm

ROA

MYR

4h 28m

1 stop

7:57 pm - 12:32 am

MYR

ROA

4h 35m

1 stop

$377Delta

Fri, Jun 5 - Thu, Jun 18

5:00 am - 10:07 am

ROA

CHS

5h 07m

1 stop

5:00 am - 10:40 am

CHS

ROA

5h 40m

1 stop

$379American Airlines

Thu, Jul 2 - Sun, Jul 5

5:00 am - 8:41 am

ROA

MYR

3h 41m

1 stop

6:06 pm - 10:20 pm

MYR

ROA

4h 14m

1 stop

$386American Airlines

Thu, Jun 18 - Mon, Jun 22

6:15 am - 10:16 am

ROA

CHS

4h 01m

1 stop

7:47 pm - 11:44 pm

CHS

ROA

3h 57m

1 stop

$389United Airlines

Tue, May 26 - Sat, May 30

United Airlines flights from Roanoke to South Carolina

Our best United Airlines deals on Roanoke to South Carolina flight tickets

United Airlines

May 30

ROA6:15 amRoanoke

4h 01m

1 stop

CHS10:16 amCharleston

Jun 3

CHS10:00 amCharleston

4h 00m

1 stop

ROA2:00 pmRoanoke

$319

United Airlines

Sep 1

ROA6:40 amRoanoke

7h 18m

1 stop

CHS1:58 pmCharleston

Sep 5

CHS10:19 amCharleston

4h 00m

1 stop

ROA2:19 pmRoanoke

$331

United Airlines

May 26

ROA6:15 amRoanoke

4h 01m

1 stop

CHS10:16 amCharleston

May 30

CHS7:47 pmCharleston

3h 57m

1 stop

ROA11:44 pmRoanoke

$389

American Airlines flights from Roanoke to South Carolina

Our best American Airlines deals on Roanoke to South Carolina flight tickets

American Airlines

Jun 5

ROA7:58 pmRoanoke

4h 01m

1 stop

CHS11:59 pmCharleston

Jun 11

CHS12:10 pmCharleston

5h 07m

1 stop

ROA5:17 pmRoanoke

$299

American Airlines

May 23

ROA6:04 pmRoanoke

5h 55m

1 stop

CHS11:59 pmCharleston

May 30

CHS5:00 amCharleston

5h 45m

1 stop

ROA10:45 amRoanoke

$333

American Airlines

Jun 6

ROA2:33 pmRoanoke

4h 21m

1 stop

MYR6:54 pmMyrtle Beach Intl

Jun 17

MYR6:50 amMyrtle Beach Intl

7h 34m

2 stops

ROA2:24 pmRoanoke

$372

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RoanokeCharleston

ROA - CHS

ROACHS

Roanoke

Fri 6/5

7:58 pm-11:59 pm

1 stop4h 01m

Charleston

Thu 6/11

12:10 pm-5:17 pm

1 stop5h 07m

$299

RoanokeMyrtle Beach

ROA - MYR

ROAMYR

Roanoke

Thu 6/11

7:59 pm-11:59 pm

1 stop4h 00m

Myrtle Beach Intl

Wed 6/17

1:54 pm-7:17 pm

1 stop5h 23m

$305

RoanokeCharleston

ROA - CHS

ROACHS

Roanoke

Sat 5/30

6:15 am-10:16 am

1 stop4h 01m

Charleston

Wed 6/3

10:00 am-2:00 pm

1 stop4h 00m

$319

RoanokeCharleston

ROA - CHS

ROACHS

Roanoke

Tue 9/1

6:40 am-1:58 pm

1 stop7h 18m

Charleston

Sat 9/5

10:19 am-2:19 pm

1 stop4h 00m

$331

RoanokeMyrtle Beach

ROA - MYR

ROAMYR

Roanoke

Fri 6/5

7:30 pm-11:58 pm

1 stop4h 28m

Myrtle Beach Intl

Tue 6/16

7:57 pm-12:32 am

1 stop4h 35m

$367

RoanokeMyrtle Beach

ROA - MYR

ROAMYR

Roanoke

Sat 6/6

2:33 pm-6:54 pm

1 stop4h 21m

Myrtle Beach Intl

Wed 6/17

6:50 am-2:24 pm

2 stops7h 34m

$372

RoanokeMyrtle Beach

ROA - MYR

ROAMYR

Roanoke

Fri 6/5

7:30 pm-11:58 pm

1 stop4h 28m

Myrtle Beach Intl

Thu 6/18

7:57 pm-12:32 am

1 stop4h 35m

$377

RoanokeCharleston

ROA - CHS

ROACHS

Roanoke

Thu 7/2

5:00 am-10:07 am

1 stop5h 07m

Charleston

Sun 7/5

5:00 am-10:40 am

1 stop5h 40m

$379

Quickest round-trip

RoanokeMyrtle Beach

ROA - MYR

ROAMYR

Roanoke

Thu 6/18

5:00 am-8:41 am

1 stop3h 41m

Myrtle Beach Intl

Mon 6/22

6:06 pm-10:20 pm

1 stop4h 14m

$386

RoanokeCharleston

ROA - CHS

ROACHS

Roanoke

Tue 5/26

6:15 am-10:16 am

1 stop4h 01m

Charleston

Sat 5/30

7:47 pm-11:44 pm

1 stop3h 57m

$389

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Roanoke to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Roanoke is in January. Flight prices, which tend to average around $144, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of January, then book flights to South Carolina from Roanoke during July instead. Flights to South Carolina in July, while not as cheap as those in January, still average around $201.

Can stopping save me money on Roanoke to South Carolina flights?

You could potentially save up to 3% on your flight if you consider stops on a Roanoke to South Carolina flight.

Cheap Roanoke to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Roanoke to South Carolina

Fastest flight time	1h 25m
Direct flights	Mon, Tue, Thu, Fri and Sun
Airports in South Carolina	57 airports

The fastest flight from Roanoke to South Carolina takes 1h 25m

Direct flights go from Roanoke to South Carolina on Monday, Tuesday, Thursday, Friday and Sunday. There are no airlines offering direct flights.

There are 57 airports in South Carolina. From Roanoke there are direct flights to Charlotte Douglas (CLT).

Search flight deals

Frequently asked questions about flying from Roanoke to South Carolina

When did momondo last update prices for flights from Roanoke Airport to South Carolina?
Prices for flights from Roanoke Airport to South Carolina are refreshed on a daily basis.
How many operators does momondo search for flights from Roanoke Airport to South Carolina?
As of May 2026, there is 1 operator available to choose from for flights from Roanoke Airport to South Carolina.
How old do you have to be to fly from Roanoke Airport to South Carolina?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Roanoke Airport to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Roanoke to South Carolina

Compare and see reviews for airlines that fly from Roanoke to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $218	Free Cancellation	Rating 7.1 11,662 reviews		Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Roanoke to South Carolina?

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Can I find flights from Roanoke to South Carolina with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Roanoke to South Carolina flights to just show those with flexible booking policies.

How can momondo help me find flights from Roanoke to South Carolina?

Once all potential Roanoke to South Carolina flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Roanoke to South Carolina right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Roanoke to South Carolina flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.