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Cheap flights from Roanoke to Key West from $245

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Roanoke to Key West departing on 9/24. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Roanoke to Key West

Cheap round-trip flights

Enter your travel dates to find the best prices.
Allegiant Air Logo
10:51 am - 8:08 amROA  Roanoke-EYW Key West
21h 17m1 stop Tampa St. Petersburg
Allegiant Air Logo
8:36 pm - 3:09 pmEYW  Key West-ROA Roanoke
18h 33m1 stop Orlando Sanford Intl
$245Allegiant Air
Thu, Sep 24 - Thu, Oct 1
Multiple Airlines Logo
3:37 pm - 12:19 pmROA  Roanoke-EYW Key West
20h 42m1 stop Tampa St. Petersburg
Multiple Airlines Logo
10:59 am - 8:51 pmEYW  Key West-ROA Roanoke
9h 52m1 stop Orlando
$288Multiple Airlines
Sun, Jan 31 - Mon, Feb 8
Multiple Airlines Logo
3:37 pm - 2:41 pmROA  Roanoke-EYW Key West
23h 04m1 stop Tampa St. Petersburg
Multiple Airlines Logo
10:59 am - 8:51 pmEYW  Key West-ROA Roanoke
9h 52m1 stop Orlando
$290Multiple Airlines
Sun, Jan 31 - Fri, Feb 5
Multiple Airlines Logo
3:37 pm - 12:19 pmROA  Roanoke-EYW Key West
20h 42m1 stop Tampa St. Petersburg
Multiple Airlines Logo
4:07 pm - 2:51 pmEYW  Key West-ROA Roanoke
22h 44m1 stop Tampa St. Petersburg
$301Multiple Airlines
Sun, Jan 31 - Sat, Feb 6
Delta Logo
6:00 am - 10:58 amROA  Roanoke-EYW Key West
4h 58m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:00 pm - 12:23 amEYW  Key West-ROA Roanoke
6h 23m1 stop Atlanta Hartsfield-Jackson
$319Delta
Sat, Jan 30 - Sat, Feb 6
Delta Logo
6:00 am - 10:58 amROA  Roanoke-EYW Key West
4h 58m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:00 pm - 12:23 amEYW  Key West-ROA Roanoke
6h 23m1 stop Atlanta Hartsfield-Jackson
$319Delta
Mon, Feb 1 - Sat, Feb 6
Delta Logo
6:00 am - 1:08 pmROA  Roanoke-EYW Key West
7h 08m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:00 pm - 12:23 amEYW  Key West-ROA Roanoke
6h 23m1 stop Atlanta Hartsfield-Jackson
$319Delta
Thu, Jan 28 - Fri, Feb 5
American Airlines Logo
1:03 pm - 6:49 pmROA  Roanoke-EYW Key West
5h 46m1 stop Charlotte Douglas
American Airlines Logo
2:15 pm - 6:38 pmEYW  Key West-ROA Roanoke
4h 23m1 stop Charlotte Douglas
$472American Airlines
Fri, Oct 9 - Tue, Oct 13
American Airlines Logo
3:30 pm - 9:47 pmROA  Roanoke-EYW Key West
6h 17m1 stop Charlotte Douglas
American Airlines Logo
6:06 am - 4:21 pmEYW  Key West-ROA Roanoke
10h 15m2 stops Miami New York LaGuardia
$488American Airlines
Sat, Jan 30 - Tue, Feb 9
American Airlines Logo
8:50 am - 7:10 pmROA  Roanoke-EYW Key West
10h 20m2 stops Charlotte Douglas Miami
American Airlines Logo
7:08 am - 12:09 pmEYW  Key West-ROA Roanoke
5h 01m1 stop Charlotte Douglas
$488American Airlines
Wed, Jan 27 - Wed, Feb 3

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Allegiant Air flights from Roanoke to Key West

Our best Allegiant Air deals on Roanoke to Key West flight tickets
Allegiant Air
Sep 24
ROA10:51 amRoanoke
21h 17m
1 stop
EYW8:08 amKey West
Oct 1
EYW8:36 pmKey West
18h 33m
1 stop
ROA3:09 pmRoanoke
$245
Allegiant Air
Aug 23
ROA10:51 amRoanoke
5h 28m
1 stop
EYW4:19 pmKey West
Aug 27
EYW6:21 pmKey West
19h 44m
1 stop
ROA2:05 pmRoanoke
$304
Allegiant Air
Aug 23
ROA10:51 amRoanoke
5h 28m
1 stop
EYW4:19 pmKey West
Aug 26
EYW12:54 pmKey West
21h 07m
1 stop
ROA10:01 amRoanoke
$311

Delta flights from Roanoke to Key West

Our best Delta deals on Roanoke to Key West flight tickets
Delta
Jan 28
ROA6:00 amRoanoke
7h 08m
1 stop
EYW1:08 pmKey West
Feb 5
EYW6:00 pmKey West
6h 23m
1 stop
ROA12:23 amRoanoke
$319
Delta
Aug 28
ROA3:32 pmRoanoke
4h 25m
1 stop
EYW7:57 pmKey West
Sep 1
EYW6:15 pmKey West
6h 12m
1 stop
ROA12:27 amRoanoke
$349
Delta
Jan 27
ROA3:25 pmRoanoke
4h 18m
1 stop
EYW7:43 pmKey West
Feb 5
EYW6:00 pmKey West
6h 23m
1 stop
ROA12:23 amRoanoke
$359

momondo Fare Finder

 
Customize your flight search to find flights from Roanoke to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 13, 2026.
Use the filters below to find and compare flights from Roanoke to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RoanokeKey West

ROA Roanoke - EYW Key West

ROAEYW

Roanoke

Thu 9/24

10:51 am-8:08 am

1 stop21h 17m

Key West

Thu 10/1

8:36 pm-3:09 pm

1 stop18h 33m

$245

RoanokeKey West

ROA Roanoke - EYW Key West

ROAEYW

Roanoke

Sun 1/31

3:37 pm-12:19 pm

1 stop20h 42m

Key West

Mon 2/8

10:59 am-8:51 pm

1 stop9h 52m

$288

RoanokeKey West

ROA Roanoke - EYW Key West

ROAEYW

Roanoke

Sun 1/31

3:37 pm-2:41 pm

1 stop23h 04m

Key West

Fri 2/5

10:59 am-8:51 pm

1 stop9h 52m

$290

RoanokeKey West

ROA Roanoke - EYW Key West

ROAEYW

Roanoke

Sun 1/31

3:37 pm-12:19 pm

1 stop20h 42m

Key West

Sat 2/6

4:07 pm-2:51 pm

1 stop22h 44m

$301

RoanokeKey West

ROA Roanoke - EYW Key West

ROAEYW

Roanoke

Sat 1/30

6:00 am-10:58 am

1 stop4h 58m

Key West

Sat 2/6

6:00 pm-12:23 am

1 stop6h 23m

$319

RoanokeKey West

ROA Roanoke - EYW Key West

ROAEYW

Roanoke

Mon 2/1

6:00 am-10:58 am

1 stop4h 58m

Key West

Sat 2/6

6:00 pm-12:23 am

1 stop6h 23m

$319

RoanokeKey West

ROA Roanoke - EYW Key West

ROAEYW

Roanoke

Thu 1/28

6:00 am-1:08 pm

1 stop7h 08m

Key West

Fri 2/5

6:00 pm-12:23 am

1 stop6h 23m

$319
Quickest round-trip

RoanokeKey West

ROA Roanoke - EYW Key West

ROAEYW

Roanoke

Fri 10/9

1:03 pm-6:49 pm

1 stop5h 46m

Key West

Tue 10/13

2:15 pm-6:38 pm

1 stop4h 23m

$472

RoanokeKey West

ROA Roanoke - EYW Key West

ROAEYW

Roanoke

Sat 1/30

3:30 pm-9:47 pm

1 stop6h 17m

Key West

Tue 2/9

6:06 am-4:21 pm

2 stops10h 15m

$488

RoanokeKey West

ROA Roanoke - EYW Key West

ROAEYW

Roanoke

Wed 1/27

8:50 am-7:10 pm

2 stops10h 20m

Key West

Wed 2/3

7:08 am-12:09 pm

1 stop5h 01m

$488

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Key West from

How to get the cheapest flight ticket from Roanoke to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Key West?

In general, December is the cheapest month to fly from Roanoke to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $318. If you are unable to visit Key West during the month of December, then departing from Roanoke during the month November is also very affordable. Most momondo users find prices during this month for around $380.

When to book flights from Roanoke to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from Roanoke to Key West according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Roanoke to Key West (ROA to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Roanoke to Key West

Fastest flight time

4h 25m

Direct flights

None
The fastest flight from Roanoke to Key West takes 4h 25m
There are no direct flights from Roanoke to Key West. There are no popular flight routes from Roanoke to Key West.
Search flight deals

Frequently asked questions about flying from Roanoke to Key West

  • How far is Roanoke to Key West by plane?

    Key West is 884.8 mi away from Roanoke. In terms of flight time, this usually takes a little over 4h 25m.

  • When did momondo last update prices for flights from Roanoke Airport to Key West Airport?

    Prices for flights from Roanoke Airport to Key West Airport were last updated today.

  • How many operators does momondo search for flights from Roanoke Airport to Key West Airport?

  • How old do you have to be to fly from Roanoke Airport to Key West Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Roanoke Airport to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The travel and health documents required for your trip to Key West Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Key West Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Roanoke to Key West?

Best airlines flying from Roanoke to Key West

Compare and see reviews for airlines that fly from Roanoke to Key West with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $248Free CancellationRating
7.1
11,923 reviews
Search American Airlines flights
DeltaPriceFrom $248Free CancellationRating
7.8
8,502 reviews
Search Delta flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from Roanoke to Key West?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Roanoke to Key West. momondo saves you time and could save you money on your trip.

Can I find flights from Roanoke to Key West with flexible booking policies on momondo?

Yes. All flights to Key West from Roanoke on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Roanoke to Key West?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Key West from Roanoke.

I’m not ready to book a flight from Roanoke to Key West right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Key West from Roanoke. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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