What is the cheapest airline that flies from Roanoke to Iowa?

American Airlines and United Airlines are the most popular carriers operating from Roanoke to Iowa

What airlines fly to Iowa?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Iowa from Roanoke according to our data. American Airlines is the first choice among our users, with 63% of people opting to fly with this airline when traveling to Iowa. Keep in mind that there are 3 different airlines that fly to Iowa on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Roanoke Airport to Iowa?

Prices for flights from Roanoke Airport to Iowa are refreshed on a daily basis.

How many operators does momondo search for flights from Roanoke Airport to Iowa?

As of September 2026, there are 2 operators available to choose from for flights from Roanoke Airport to Iowa.

How old do you have to be to fly from Roanoke Airport to Iowa?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Roanoke Airport to Iowa.

What documentation or ID do you need to fly to Iowa?

The necessary travel and health documents for your Iowa trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$284 Cheap Flights from Roanoke to Iowa in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Roanoke to Iowa

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:15 am - 10:48 amROA Roanoke-DSM Des Moines

5h 33m1 stop Charlotte Douglas

8:07 am - 1:49 pmDSM Des Moines-ROA Roanoke

4h 42m1 stop Charlotte Douglas

$339American Airlines

Fri, Dec 11 - Mon, Dec 14

5:01 am - 10:48 amROA Roanoke-DSM Des Moines

6h 47m1 stop Charlotte Douglas

7:06 am - 12:43 pmDSM Des Moines-ROA Roanoke

4h 37m1 stop Charlotte Douglas

$339American Airlines

Fri, Dec 4 - Sun, Dec 6

6:55 pm - 10:38 pmROA Roanoke-DSM Des Moines

4h 43m1 stop Atlanta Hartsfield-Jackson

11:35 am - 6:15 pmDSM Des Moines-ROA Roanoke

5h 40m1 stop Atlanta Hartsfield-Jackson

$339Delta

Fri, Dec 11 - Sun, Dec 13

6:15 am - 10:48 amROA Roanoke-DSM Des Moines

5h 33m1 stop Charlotte Douglas

9:25 am - 4:22 pmDSM Des Moines-ROA Roanoke

5h 57m1 stop Chicago O'Hare Intl

$339American Airlines

Fri, Dec 11 - Sun, Dec 13

4:14 pm - 12:26 amROA Roanoke-DSM Des Moines

9h 12m2 stops Charlotte Douglas Chicago O'Hare Intl

7:06 am - 12:43 pmDSM Des Moines-ROA Roanoke

4h 37m1 stop Charlotte Douglas

$344American Airlines

Fri, Dec 4 - Sun, Dec 6

5:51 pm - 9:23 pmROA Roanoke-DSM Des Moines

4h 32m1 stop Chicago O'Hare Intl

3:11 pm - 11:44 pmDSM Des Moines-ROA Roanoke

7h 33m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

$359United Airlines

Tue, Oct 13 - Mon, Oct 19

6:38 pm - 10:33 pmROA Roanoke-DSM Des Moines

4h 55m1 stop Atlanta Hartsfield-Jackson

4:07 pm - 9:57 pmDSM Des Moines-ROA Roanoke

4h 50m1 stop Atlanta Hartsfield-Jackson

$369Delta

Tue, Oct 13 - Sat, Oct 17

10:53 am - 2:15 pmROA Roanoke-DSM Des Moines

4h 22m1 stop Chicago O'Hare Intl

1:26 pm - 11:44 pmDSM Des Moines-ROA Roanoke

9h 18m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

$374United Airlines

Tue, Oct 13 - Sat, Oct 17

10:35 am - 9:23 pmROA Roanoke-DSM Des Moines

11h 48m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl

1:26 pm - 11:44 pmDSM Des Moines-ROA Roanoke

9h 18m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

$379United Airlines

Tue, Oct 13 - Sat, Oct 17

10:35 am - 9:23 pmROA Roanoke-DSM Des Moines

11h 48m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl

3:11 pm - 11:44 pmDSM Des Moines-ROA Roanoke

7h 33m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

$394United Airlines

Tue, Oct 13 - Mon, Oct 19

Cheap last minute flights

Enter your travel dates to find the best prices.

5:47 pm - 12:04 amROA Roanoke-DSM Des Moines

7h 17m1 stop Chicago O'Hare Intl

7:41 am - 4:50 pmDSM Des Moines-ROA Roanoke

8h 09m1 stop New York LaGuardia

$540American Airlines

Fri, Oct 2 - Sun, Oct 4

3:27 pm - 12:04 amROA Roanoke-DSM Des Moines

9h 37m2 stops Charlotte Douglas Chicago O'Hare Intl

7:41 am - 4:50 pmDSM Des Moines-ROA Roanoke

8h 09m1 stop New York LaGuardia

$545American Airlines

Fri, Oct 2 - Sun, Oct 4

5:47 pm - 12:04 amROA Roanoke-DSM Des Moines

7h 17m1 stop Chicago O'Hare Intl

7:41 am - 4:50 pmDSM Des Moines-ROA Roanoke

8h 09m1 stop New York LaGuardia

$555American Airlines

Fri, Oct 2 - Sun, Oct 4

5:51 pm - 11:35 pmROA Roanoke-DSM Des Moines

6h 44m1 stop Chicago O'Hare Intl

3:11 pm - 10:59 pmDSM Des Moines-ROA Roanoke

6h 48m1 stop Chicago O'Hare Intl

$574United Airlines

Fri, Oct 2 - Sun, Oct 4

10:35 am - 10:15 pmROA Roanoke-DSM Des Moines

12h 40m2 stops Washington, D.C. Dulles Intl Houston George Bush Intcntl

3:11 pm - 10:59 pmDSM Des Moines-ROA Roanoke

6h 48m1 stop Chicago O'Hare Intl

$580United Airlines

Fri, Oct 2 - Sun, Oct 4

5:47 pm - 12:04 amROA Roanoke-DSM Des Moines

7h 17m1 stop Chicago O'Hare Intl

7:41 am - 4:50 pmDSM Des Moines-ROA Roanoke

8h 09m1 stop New York LaGuardia

$601American Airlines

Fri, Oct 2 - Sun, Oct 4

10:35 am - 10:15 pmROA Roanoke-DSM Des Moines

12h 40m2 stops Washington, D.C. Dulles Intl Houston George Bush Intcntl

3:11 pm - 10:59 pmDSM Des Moines-ROA Roanoke

6h 48m1 stop Chicago O'Hare Intl

$623United Airlines

Fri, Oct 2 - Sun, Oct 4

5:47 pm - 12:04 amROA Roanoke-DSM Des Moines

7h 17m1 stop Chicago O'Hare Intl

7:41 am - 4:50 pmDSM Des Moines-ROA Roanoke

8h 09m1 stop New York LaGuardia

$648American Airlines

Fri, Oct 2 - Sun, Oct 4

10:53 am - 11:48 pmROA Roanoke-DSM Des Moines

13h 55m2 stops Chicago O'Hare Intl Denver Intl

3:11 pm - 10:59 pmDSM Des Moines-ROA Roanoke

6h 48m1 stop Chicago O'Hare Intl

$678United Airlines

Fri, Oct 2 - Sun, Oct 4

10:53 am - 11:48 pmROA Roanoke-DSM Des Moines

13h 55m2 stops Chicago O'Hare Intl Denver Intl

3:11 pm - 10:59 pmDSM Des Moines-ROA Roanoke

6h 48m1 stop Chicago O'Hare Intl

$728United Airlines

Fri, Oct 2 - Sun, Oct 4

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United Airlines flights from Roanoke to Iowa

Our best United Airlines deals on Roanoke to Iowa flight tickets

United Airlines

Oct 13

ROA10:53 amRoanoke

4h 22m

1 stop

DSM2:15 pmDes Moines

Oct 17

DSM1:26 pmDes Moines

9h 18m

2 stops

ROA11:44 pmRoanoke

$374

United Airlines

Oct 13

ROA10:35 amRoanoke

11h 48m

2 stops

DSM9:23 pmDes Moines

Oct 17

DSM1:26 pmDes Moines

9h 18m

2 stops

ROA11:44 pmRoanoke

$379

United Airlines

Dec 5

ROA10:25 amRoanoke

5h 01m

1 stop

DSM2:26 pmDes Moines

Dec 9

DSM3:20 pmDes Moines

4h 44m

1 stop

ROA9:04 pmRoanoke

$439

American Airlines flights from Roanoke to Iowa

Our best American Airlines deals on Roanoke to Iowa flight tickets

American Airlines

Oct 10

ROA6:10 pmRoanoke

6h 48m

1 stop

CID11:58 pmCedar Rapids

Oct 14

CID7:00 amCedar Rapids

4h 33m

1 stop

ROA12:33 pmRoanoke

$437

American Airlines

Oct 13

ROA5:13 pmRoanoke

5h 11m

1 stop

DSM9:24 pmDes Moines

Oct 18

DSM7:08 amDes Moines

4h 25m

1 stop

ROA12:33 pmRoanoke

$464

American Airlines

Oct 10

ROA8:15 amRoanoke

10h 09m

2 stops

CID5:24 pmCedar Rapids

Oct 14

CID7:00 amCedar Rapids

4h 33m

1 stop

ROA12:33 pmRoanoke

$488

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RoanokeDes Moines

ROA Roanoke - DSM Des Moines

ROADSM

Roanoke

Fri 12/11

6:15 am-10:48 am

1 stop5h 33m

Des Moines

Mon 12/14

8:07 am-1:49 pm

1 stop4h 42m

$339

RoanokeDes Moines

ROA Roanoke - DSM Des Moines

ROADSM

Roanoke

Fri 12/4

5:01 am-10:48 am

1 stop6h 47m

Des Moines

Sun 12/6

7:06 am-12:43 pm

1 stop4h 37m

$339

RoanokeDes Moines

ROA Roanoke - DSM Des Moines

ROADSM

Roanoke

Fri 12/11

6:55 pm-10:38 pm

1 stop4h 43m

Des Moines

Sun 12/13

11:35 am-6:15 pm

1 stop5h 40m

$339

RoanokeDes Moines

ROA Roanoke - DSM Des Moines

ROADSM

Roanoke

Fri 12/11

6:15 am-10:48 am

1 stop5h 33m

Des Moines

Sun 12/13

9:25 am-4:22 pm

1 stop5h 57m

$339

RoanokeDes Moines

ROA Roanoke - DSM Des Moines

ROADSM

Roanoke

Fri 12/4

4:14 pm-12:26 am

2 stops9h 12m

Des Moines

Sun 12/6

7:06 am-12:43 pm

1 stop4h 37m

$344

RoanokeDes Moines

ROA Roanoke - DSM Des Moines

ROADSM

Roanoke

Tue 10/13

5:51 pm-9:23 pm

1 stop4h 32m

Des Moines

Mon 10/19

3:11 pm-11:44 pm

2 stops7h 33m

$359

Quickest round-trip

RoanokeDes Moines

ROA Roanoke - DSM Des Moines

ROADSM

Roanoke

Tue 10/13

6:38 pm-10:33 pm

1 stop4h 55m

Des Moines

Sat 10/17

4:07 pm-9:57 pm

1 stop4h 50m

$369

RoanokeDes Moines

ROA Roanoke - DSM Des Moines

ROADSM

Roanoke

Tue 10/13

10:53 am-2:15 pm

1 stop4h 22m

Des Moines

Sat 10/17

1:26 pm-11:44 pm

2 stops9h 18m

$374

RoanokeDes Moines

ROA Roanoke - DSM Des Moines

ROADSM

Roanoke

Tue 10/13

10:35 am-9:23 pm

2 stops11h 48m

Des Moines

Sat 10/17

1:26 pm-11:44 pm

2 stops9h 18m

$379

RoanokeDes Moines

ROA Roanoke - DSM Des Moines

ROADSM

Roanoke

Tue 10/13

10:35 am-9:23 pm

2 stops11h 48m

Des Moines

Mon 10/19

3:11 pm-11:44 pm

2 stops7h 33m

$394

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first

How to get the cheapest flight ticket from Roanoke to Iowa

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Iowa?

The month of September is another great option to travel to Iowa, with average flight prices from Roanoke averaging around $348.

Cheap Roanoke to Iowa flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Roanoke to Iowa

Best Price Found	$284
Fastest flight time	4h 09m
Direct flights	None

The best one-way flight to Iowa from Roanoke in the past 72 hours is $284. The best round-trip flight deal from Roanoke to Iowa found on momondo in the last 72 hours is $339.

The fastest flight from Roanoke to Iowa takes 4h 09m

There are no direct flights from Roanoke to Iowa. There are no popular flight routes from Roanoke to Iowa.

Search flight deals

Frequently asked questions about flying from Roanoke to Iowa

When did momondo last update prices for flights from Roanoke Airport to Iowa?
Prices for flights from Roanoke Airport to Iowa are refreshed on a daily basis.
How many operators does momondo search for flights from Roanoke Airport to Iowa?
As of September 2026, there are 2 operators available to choose from for flights from Roanoke Airport to Iowa.
How old do you have to be to fly from Roanoke Airport to Iowa?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Roanoke Airport to Iowa.
What documentation or ID do you need to fly to Iowa?
The necessary travel and health documents for your Iowa trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Roanoke to Iowa

Compare and see reviews for airlines that fly from Roanoke to Iowa with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $274	Free Cancellation	Rating 7.0 12,097 reviews		Search American Airlines flights
United Airlines	PriceFrom $318	Free Cancellation	Rating 7.4 10,245 reviews		Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Roanoke to Iowa?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Iowa from Roanoke.

Can I find flights from Roanoke to Iowa with flexible booking policies on momondo?

All flight searches from Roanoke to Iowa on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Roanoke to Iowa?

Once you have performed a search for Roanoke to Iowa flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Roanoke to Iowa right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Roanoke to Iowa flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.