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Cheap flights from Prague to South Carolina from $485

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Prague to South Carolina departing on 4/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Prague to South Carolina

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
10:25 am - 11:59 pm
PRG
-
CLT
19h 34m2 stops
Multiple Airlines Logo
9:06 am - 9:45 am
CLT
-
PRG
18h 39m2 stops
$621Multiple Airlines
Mon, Jan 12 - Sun, Jan 18
Multiple Airlines Logo
10:25 am - 11:59 pm
PRG
-
CLT
19h 34m2 stops
Multiple Airlines Logo
7:00 am - 9:45 am
CLT
-
PRG
20h 45m3 stops
$662Multiple Airlines
Mon, Jan 12 - Sun, Jan 18
Multiple Airlines Logo
7:35 am - 8:57 pm
PRG
-
CLT
19h 22m2 stops
Multiple Airlines Logo
6:50 pm - 1:05 pm
CLT
-
PRG
12h 15m1 stop
$853Multiple Airlines
Mon, Jan 12 - Sun, Jan 18
Air Canada Logo
7:35 am - 4:17 pm
PRG
-
CLT
14h 42m2 stops
Air Canada Logo
7:50 am - 1:55 pm
CLT
-
PRG
24h 05m2 stops
$867Air Canada
Thu, Feb 5 - Mon, Feb 9
United Airlines Logo
12:10 pm - 11:44 pm
PRG
-
CAE
17h 34m2 stops
United Airlines Logo
2:39 pm - 1:55 pm
CAE
-
PRG
17h 16m2 stops
$869United Airlines
Fri, Feb 13 - Tue, Feb 17
United Airlines Logo
7:35 am - 8:02 pm
PRG
-
CHS
18h 27m2 stops
United Airlines Logo
2:58 pm - 1:55 pm
CHS
-
PRG
16h 57m2 stops
$869United Airlines
Fri, Jan 23 - Tue, Jan 27
American Airlines Logo
10:30 am - 7:05 pm
PRG
-
CLT
14h 35m1 stop
American Airlines Logo
8:25 pm - 2:00 pm
CLT
-
PRG
11h 35m1 stop
$882American Airlines
Thu, Feb 5 - Mon, Feb 9
American Airlines Logo
6:45 am - 4:05 pm
PRG
-
CLT
15h 20m1 stop
American Airlines Logo
6:08 pm - 5:30 pm
CLT
-
PRG
17h 22m2 stops
$887American Airlines
Thu, Feb 5 - Mon, Feb 9
Scandinavian Airlines Logo
10:25 am - 10:12 pm
PRG
-
CLT
17h 47m2 stops
Scandinavian Airlines Logo
11:38 am - 9:45 am
CLT
-
PRG
16h 07m2 stops
$943Scandinavian Airlines
Thu, Feb 5 - Mon, Feb 9
Scandinavian Airlines Logo
10:25 am - 10:22 pm
PRG
-
CHS
17h 57m2 stops
Scandinavian Airlines Logo
6:00 am - 6:40 pm
CHS
-
PRG
30h 40m2 stops
$943Scandinavian Airlines
Fri, Jan 23 - Tue, Jan 27

American Airlines flights from Prague to South Carolina

Our best American Airlines deals on Prague to South Carolina flight tickets
American Airlines
Feb 5
PRG10:30 amVáclav Havel Prague
14h 35m
1 stop
CLT7:05 pmCharlotte Douglas
Feb 9
CLT8:25 pmCharlotte Douglas
11h 35m
1 stop
PRG2:00 pmVáclav Havel Prague
$882
Find similar
American Airlines
Feb 5
PRG6:45 amVáclav Havel Prague
15h 20m
1 stop
CLT4:05 pmCharlotte Douglas
Feb 9
CLT6:08 pmCharlotte Douglas
17h 22m
2 stops
PRG5:30 pmVáclav Havel Prague
$887
Find similar
American Airlines
Jan 22
PRG6:45 amVáclav Havel Prague
17h 15m
2 stops
MYR6:00 pmMyrtle Beach Intl
Jan 25
MYR5:29 pmMyrtle Beach Intl
18h 41m
2 stops
PRG6:10 pmVáclav Havel Prague
$909
Find similar

United Airlines flights from Prague to South Carolina

Our best United Airlines deals on Prague to South Carolina flight tickets
United Airlines
Jan 23
PRG7:35 amVáclav Havel Prague
18h 27m
2 stops
CHS8:02 pmCharleston
Jan 27
CHS2:58 pmCharleston
16h 57m
2 stops
PRG1:55 pmVáclav Havel Prague
$869
Find similar
United Airlines
Jan 23
PRG7:35 amVáclav Havel Prague
37h 13m
2 stops
CHS2:48 pmCharleston
Jan 27
CHS2:58 pmCharleston
16h 57m
2 stops
PRG1:55 pmVáclav Havel Prague
$882
Find similar
United Airlines
Dec 18
PRG7:35 amVáclav Havel Prague
32h 28m
2 stops
CLT10:03 amCharlotte Douglas
Jan 5
CLT10:00 amCharlotte Douglas
21h 05m
2 stops
PRG1:05 pmVáclav Havel Prague
$921
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Prague to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 5, 2025.
Use the filters below to find and compare flights from Prague to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PragueCharlotte

PRG - CLT

PRGCLT

Václav Havel Prague

Mon 1/12

10:25 am-11:59 pm

2 stops19h 34m

Charlotte Douglas

Sun 1/18

9:06 am-9:45 am

2 stops18h 39m

$621

PragueCharlotte

PRG - CLT

PRGCLT

Václav Havel Prague

Mon 1/12

10:25 am-11:59 pm

2 stops19h 34m

Charlotte Douglas

Sun 1/18

7:00 am-9:45 am

3 stops20h 45m

$662

PragueCharlotte

PRG - CLT

PRGCLT

Václav Havel Prague

Mon 1/12

7:35 am-8:57 pm

2 stops19h 22m

Charlotte Douglas

Sun 1/18

6:50 pm-1:05 pm

1 stop12h 15m

$853

PragueCharlotte

PRG - CLT

PRGCLT

Václav Havel Prague

Thu 2/5

7:35 am-4:17 pm

2 stops14h 42m

Charlotte Douglas

Mon 2/9

7:50 am-1:55 pm

2 stops24h 05m

$867

PragueColumbia

PRG - CAE

PRGCAE

Václav Havel Prague

Fri 2/13

12:10 pm-11:44 pm

2 stops17h 34m

Columbia Metropolitan

Tue 2/17

2:39 pm-1:55 pm

2 stops17h 16m

$869

PragueCharleston

PRG - CHS

PRGCHS

Václav Havel Prague

Fri 1/23

7:35 am-8:02 pm

2 stops18h 27m

Charleston

Tue 1/27

2:58 pm-1:55 pm

2 stops16h 57m

$869

PragueCharlotte

PRG - CLT

PRGCLT

Václav Havel Prague

Thu 2/5

10:30 am-7:05 pm

1 stop14h 35m

Charlotte Douglas

Mon 2/9

8:25 pm-2:00 pm

1 stop11h 35m

$882

PragueCharlotte

PRG - CLT

PRGCLT

Václav Havel Prague

Thu 2/5

6:45 am-4:05 pm

1 stop15h 20m

Charlotte Douglas

Mon 2/9

6:08 pm-5:30 pm

2 stops17h 22m

$887

PragueCharlotte

PRG - CLT

PRGCLT

Václav Havel Prague

Thu 2/5

10:25 am-10:12 pm

2 stops17h 47m

Charlotte Douglas

Mon 2/9

11:38 am-9:45 am

2 stops16h 07m

$943

PragueCharleston

PRG - CHS

PRGCHS

Václav Havel Prague

Fri 1/23

10:25 am-10:22 pm

2 stops17h 57m

Charleston

Tue 1/27

6:00 am-6:40 pm

2 stops30h 40m

$943

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to South Carolina from

How to get the cheapest flight ticket from Prague to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Tuesday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $926. The most expensive day to fly to South Carolina is Sunday, with ticket prices averaging around $1,135.

Cheap Prague to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Prague to South Carolina

Fastest flight time

12h 24m

Direct flights

None
The fastest flight from Prague to South Carolina takes 12h 24m
There are no direct flights from Prague to South Carolina. There are no popular flight routes from Prague to South Carolina.
Search flight deals

  • When did momondo last update prices for flights from Václav Havel Prague Airport to South Carolina?

    Prices for flights from Václav Havel Prague Airport to South Carolina are updated daily.

  • How many operators does momondo search for flights from Václav Havel Prague Airport to South Carolina?

  • How old do you have to be to fly from Václav Havel Prague Airport to South Carolina?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Václav Havel Prague Airport to South Carolina.

  • What documentation or ID do you need to fly to South Carolina?

    The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Prague to South Carolina

Compare and see reviews for airlines that fly from Prague to South Carolina with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $810Free CancellationRating
7.9
8,010 reviews
Search Delta flights
United AirlinesPriceFrom $893Free CancellationRating
7.4
9,063 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Prague to South Carolina?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Prague to South Carolina. momondo saves you time and could save you money on your trip.

Can I find flights from Prague to South Carolina with flexible booking policies on momondo?

All flight searches from Prague to South Carolina on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Prague to South Carolina?

Once you have performed a search for Prague to South Carolina flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Prague to South Carolina right now. Can momondo alert me if prices change?

Price alerts on flights to South Carolina from Prague are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your South Carolina trip

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